Rapid and transient palmitoylation of the tyrosine kinase Lck mediates Fas signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 38, 2015, Pages 11876-11880

  Akimzhanov, Askar M ^a   Boehning, Darren ^a   Snyder, Solomon H ^b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Calcium; Fas; Lck; Protein palmitoylation

Indexed keywords

ACYLTRANSFERASE; CALCIUM ION; FAS ANTIGEN; FAS LIGAND; PALMITIC ACID; PHOSPHOLIPASE C GAMMA1; PROTEIN DHHC21; PROTEIN KINASE LCK; PROTEIN KINASE ZAP 70; UNCLASSIFIED DRUG; 1,2-BIS(2-AMINOPHENOXY)ETHANE N,N,N',N'-TETRAACETIC ACID ACETOXYMETHYL ESTER; 1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N',N'-TETRAACETIC ACID; CALCIUM; EGTAZIC ACID; FAS PROTEIN, HUMAN; PHOSPHOLIPASE C GAMMA;

APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME KINETICS; HUMAN; HUMAN CELL; LIPID RAFT; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TURNOVER TIME; ANALOGS AND DERIVATIVES; CELL MEMBRANE; DRUG EFFECTS; HELA CELL LINE; INTRACELLULAR SPACE; JURKAT CELL LINE; LIPOYLATION; METABOLISM; PROTEIN TRANSPORT; STAINING; T LYMPHOCYTE; TEMPERATURE;

ACYLTRANSFERASES; ANTIGENS, CD95; APOPTOSIS; CALCIUM; EGTAZIC ACID; ENZYME ACTIVATION; HELA CELLS; HUMANS; INTRACELLULAR SPACE; JURKAT CELLS; LIPOYLATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE MICRODOMAINS; PALMITIC ACID; PHOSPHOLIPASE C GAMMA; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; STAINING AND LABELING; T-LYMPHOCYTES; TEMPERATURE;

EID: 84942938808     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1509929112     Document Type: Article

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