메뉴 건너뛰기




Volumn 75, Issue 4, 2014, Pages 322-329

The role of TLR2, TLR4 and CD36 in macrophage activation and foam cell formation in response to oxLDL in humans

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN; CD86 ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; OXIDIZED LOW DENSITY LIPOPROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

EID: 84895509356     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2014.01.012     Document Type: Article
Times cited : (110)

References (35)
  • 1
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 2002, 420:868-874.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 2
    • 79251580687 scopus 로고    scopus 로고
    • Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity
    • Miller Y.I., Choi S.H., Wiesner P., Fang L., Harkewicz R., Hartvigsen K., et al. Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circ Res 2011, 108:235-348.
    • (2011) Circ Res , vol.108 , pp. 235-348
    • Miller, Y.I.1    Choi, S.H.2    Wiesner, P.3    Fang, L.4    Harkewicz, R.5    Hartvigsen, K.6
  • 3
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001, 1135-1145.
    • (2001) Nat Rev Immunol , pp. 1135-1145
    • Medzhitov, R.1
  • 4
    • 34548442991 scopus 로고    scopus 로고
    • Coordinating TLR-activated signaling pathways in cells of the immune system
    • Bannered A., Gerondakis S. Coordinating TLR-activated signaling pathways in cells of the immune system. Immunol Cell Biol 2007, 85:420-424.
    • (2007) Immunol Cell Biol , vol.85 , pp. 420-424
    • Bannered, A.1    Gerondakis, S.2
  • 5
    • 77955851805 scopus 로고    scopus 로고
    • The effects of ox-LDL in human atherosclerosis may be mediated in part via the toll-like receptor 4 pathway
    • Geng H., Wang A., Rong G., Zhu B., Deng Y., Chen J., et al. The effects of ox-LDL in human atherosclerosis may be mediated in part via the toll-like receptor 4 pathway. Mol Cell Biochem 2010, 342:201-206.
    • (2010) Mol Cell Biochem , vol.342 , pp. 201-206
    • Geng, H.1    Wang, A.2    Rong, G.3    Zhu, B.4    Deng, Y.5    Chen, J.6
  • 6
    • 77954760594 scopus 로고    scopus 로고
    • Activation of TLR2 and TLR4 by minimally modified low-density lipoprotein in human macrophages and monocytes triggers the inflammatory response
    • Chávez-Sánchez L., Madrid-Miller A., Chávez-Rueda K., Legorreta-Haquet M.V., Tesoro-Cruz E., Blanco-Favela F. Activation of TLR2 and TLR4 by minimally modified low-density lipoprotein in human macrophages and monocytes triggers the inflammatory response. Hum Immunol 2010, 71:737-744.
    • (2010) Hum Immunol , vol.71 , pp. 737-744
    • Chávez-Sánchez, L.1    Madrid-Miller, A.2    Chávez-Rueda, K.3    Legorreta-Haquet, M.V.4    Tesoro-Cruz, E.5    Blanco-Favela, F.6
  • 7
    • 0033847712 scopus 로고    scopus 로고
    • LDL Oxidized -induced NF-kappa B activation and subsequent expression of proinflammatory genes are defective in monocyte-derived macrophages from CD36-deficient patients
    • Janabi M., Yamashita S., Hirano K., Sakai N., Hiraoka H., Matsumoto K., et al. LDL Oxidized -induced NF-kappa B activation and subsequent expression of proinflammatory genes are defective in monocyte-derived macrophages from CD36-deficient patients. Arterioscler Thromb Vasc Biol 2000, 20:1953-1960.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1953-1960
    • Janabi, M.1    Yamashita, S.2    Hirano, K.3    Sakai, N.4    Hiraoka, H.5    Matsumoto, K.6
  • 8
    • 0035021877 scopus 로고    scopus 로고
    • Monocytes influence the fate of T cells challenged with oxidised low density lipoproteins towards apoptosis or MHC-restricted proliferation
    • Fortun A., Khalil A., Gagné D., Douziech N., Kuntz C., Jay-Gerin J.P., et al. Monocytes influence the fate of T cells challenged with oxidised low density lipoproteins towards apoptosis or MHC-restricted proliferation. Atherosclerosis 2001, 156:11-21.
    • (2001) Atherosclerosis , vol.156 , pp. 11-21
    • Fortun, A.1    Khalil, A.2    Gagné, D.3    Douziech, N.4    Kuntz, C.5    Jay-Gerin, J.P.6
  • 9
    • 34547868877 scopus 로고    scopus 로고
    • 'Danger' effect of low-density lipoprotein (LDL) and oxidized LDL on human immature dendritic cells
    • Zaguri R., Verbovetski I., Atallah M., Trahtemberg U., Krispin A., Nahari E., et al. 'Danger' effect of low-density lipoprotein (LDL) and oxidized LDL on human immature dendritic cells. Clin Exp Immunol 2007, 149(3):543-552.
    • (2007) Clin Exp Immunol , vol.149 , Issue.3 , pp. 543-552
    • Zaguri, R.1    Verbovetski, I.2    Atallah, M.3    Trahtemberg, U.4    Krispin, A.5    Nahari, E.6
  • 10
    • 27644568878 scopus 로고    scopus 로고
    • Modulation of atherosclerosis in mice by toll-like receptor 2
    • Mullick A.E., Tobias P.S., Curtiss L.K. Modulation of atherosclerosis in mice by toll-like receptor 2. J Clin Invest 2005, 115:3149-3156.
    • (2005) J Clin Invest , vol.115 , pp. 3149-3156
    • Mullick, A.E.1    Tobias, P.S.2    Curtiss, L.K.3
  • 12
    • 67650266902 scopus 로고    scopus 로고
    • Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake
    • Choi S.H., Harkewicz R., Lee J.H., Boullier A., Almazan F., Li A.C., et al. Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake. Circ Res 2009, 104:1355-1363.
    • (2009) Circ Res , vol.104 , pp. 1355-1363
    • Choi, S.H.1    Harkewicz, R.2    Lee, J.H.3    Boullier, A.4    Almazan, F.5    Li, A.C.6
  • 13
    • 38049029104 scopus 로고    scopus 로고
    • Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids
    • Liu X., Ukai T., Yumoto H., Davey M., Goswami S., Gibson F.C., et al. Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids. Atherosclerosis 2008, 196:146-154.
    • (2008) Atherosclerosis , vol.196 , pp. 146-154
    • Liu, X.1    Ukai, T.2    Yumoto, H.3    Davey, M.4    Goswami, S.5    Gibson, F.C.6
  • 15
    • 0034101821 scopus 로고    scopus 로고
    • Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice
    • Febbraio M., Podrez E.A., Smith J.D., Hajjar D.P., Hazen S.L., Hoff H.F., et al. Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice. J Clin Invest 2000, 105:1049-1056.
    • (2000) J Clin Invest , vol.105 , pp. 1049-1056
    • Febbraio, M.1    Podrez, E.A.2    Smith, J.D.3    Hajjar, D.P.4    Hazen, S.L.5    Hoff, H.F.6
  • 17
    • 0346037268 scopus 로고    scopus 로고
    • Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages
    • Kunjathoor V.V., Febbraio M., Podrez E.A., Moore K.J., Andersson L., Koehn S., et al. Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages. J Biol Chem 2002, 277:49982-49988.
    • (2002) J Biol Chem , vol.277 , pp. 49982-49988
    • Kunjathoor, V.V.1    Febbraio, M.2    Podrez, E.A.3    Moore, K.J.4    Andersson, L.5    Koehn, S.6
  • 18
    • 23644435612 scopus 로고    scopus 로고
    • Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice
    • Moore K.J., Kunjathoor V.V., Koehn S.L., Manning J.J., Tseng A.A., Silver J.M., et al. Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice. J Clin Invest 2005, 115:2192-2201.
    • (2005) J Clin Invest , vol.115 , pp. 2192-2201
    • Moore, K.J.1    Kunjathoor, V.V.2    Koehn, S.L.3    Manning, J.J.4    Tseng, A.A.5    Silver, J.M.6
  • 21
    • 80054714613 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates oxidized LDL-induced macrophage differentiation to foam cells
    • Howell K.W., Meng X., Fullerton D.A., Jin C., Reece T.B., Cleveland J.C. Toll-like receptor 4 mediates oxidized LDL-induced macrophage differentiation to foam cells. J Surg Res 2011, 171:e27-e31.
    • (2011) J Surg Res , vol.171
    • Howell, K.W.1    Meng, X.2    Fullerton, D.A.3    Jin, C.4    Reece, T.B.5    Cleveland, J.C.6
  • 22
    • 33646882893 scopus 로고    scopus 로고
    • Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis
    • Roelofs M.F., Boelens W.C., Joosten L.A., Abdollahi-Roodsaz S., Geurts J., Wunderink L.U., et al. Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis. J Immunol 2006, 176:7021-7027.
    • (2006) J Immunol , vol.176 , pp. 7021-7027
    • Roelofs, M.F.1    Boelens, W.C.2    Joosten, L.A.3    Abdollahi-Roodsaz, S.4    Geurts, J.5    Wunderink, L.U.6
  • 24
    • 34548160715 scopus 로고    scopus 로고
    • Enhanced levels of oxidized low-density lipoprotein prime monocytes to cytokine overproduction via upregulation of CD14 and toll-like receptor 4 in unstable angina
    • Pasini A.F., Anselmi M., Garbin U., Franchi E., Stranieri C., Nava M.C., et al. Enhanced levels of oxidized low-density lipoprotein prime monocytes to cytokine overproduction via upregulation of CD14 and toll-like receptor 4 in unstable angina. Arterioscler Thromb Vasc Biol 2007, 27:1991-1997.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1991-1997
    • Pasini, A.F.1    Anselmi, M.2    Garbin, U.3    Franchi, E.4    Stranieri, C.5    Nava, M.C.6
  • 25
    • 84880777411 scopus 로고    scopus 로고
    • CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
    • Sheedy F.J., Grebe A., Rayner K.J., Kalantari P., Ramkhelawon B., Carpenter S.B., et al. CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation. Nat Immunol 2013, 14:812-820.
    • (2013) Nat Immunol , vol.14 , pp. 812-820
    • Sheedy, F.J.1    Grebe, A.2    Rayner, K.J.3    Kalantari, P.4    Ramkhelawon, B.5    Carpenter, S.B.6
  • 26
    • 0034194473 scopus 로고    scopus 로고
    • CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex
    • Masternak K., Muhlethaler-Mottet A., Villard J., Zufferey M., Steimle V., et al. CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex. Genes Dev 2000, 14:1156-1166.
    • (2000) Genes Dev , vol.14 , pp. 1156-1166
    • Masternak, K.1    Muhlethaler-Mottet, A.2    Villard, J.3    Zufferey, M.4    Steimle, V.5
  • 27
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg A.M. CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002, 20:709-760.
    • (2002) Annu Rev Immunol , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 28
    • 34247224360 scopus 로고    scopus 로고
    • Toll-like receptor 2-mediated dendritic cell activation by a Porphyromonas gingivalis synthetic lipopeptide
    • Asai Y., Makimura Y., Ogawa T. Toll-like receptor 2-mediated dendritic cell activation by a Porphyromonas gingivalis synthetic lipopeptide. J Med Microbiol 2007, 56:459-465.
    • (2007) J Med Microbiol , vol.56 , pp. 459-465
    • Asai, Y.1    Makimura, Y.2    Ogawa, T.3
  • 29
    • 0035865232 scopus 로고    scopus 로고
    • Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2
    • Hertz C.J., Kiertscher S.M., Godowski P.J., Bouis D.A., Norgard M.V., Roth M.D., et al. Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2. J Immunol 2001, 166:2444-2450.
    • (2001) J Immunol , vol.166 , pp. 2444-2450
    • Hertz, C.J.1    Kiertscher, S.M.2    Godowski, P.J.3    Bouis, D.A.4    Norgard, M.V.5    Roth, M.D.6
  • 30
    • 77954760985 scopus 로고    scopus 로고
    • Immunomodulatory nanoparticles as adjuvants and allergen-delivery system to human dendritic cells: implications for specific immunotherapy
    • Broos S., Lundberg K., Akagi T., Kadowaki K., Akashi M., Greiff L., et al. Immunomodulatory nanoparticles as adjuvants and allergen-delivery system to human dendritic cells: implications for specific immunotherapy. Vaccine 2010, 28:5075-5085.
    • (2010) Vaccine , vol.28 , pp. 5075-5085
    • Broos, S.1    Lundberg, K.2    Akagi, T.3    Kadowaki, K.4    Akashi, M.5    Greiff, L.6
  • 31
    • 82255191977 scopus 로고    scopus 로고
    • TLR-dependent T cell activation in autoimmunity
    • Mills K.H. TLR-dependent T cell activation in autoimmunity. Nat Rev Immunol 2011, 11:807-822.
    • (2011) Nat Rev Immunol , vol.11 , pp. 807-822
    • Mills, K.H.1
  • 33
    • 63749108516 scopus 로고    scopus 로고
    • Interferon gamma: a master regulator of atherosclerosis
    • McLaren J.E., Ramji D.P. Interferon gamma: a master regulator of atherosclerosis. Cytokine Growth Factor Rev 2009, 20:125-135.
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 125-135
    • McLaren, J.E.1    Ramji, D.P.2
  • 35
    • 75649087741 scopus 로고    scopus 로고
    • CD36 ligands promote sterile inflammation through assembly of a toll-like receptor 4 and 6 heterodimer
    • Stewart C.R., Stuart L.M., Wilkinson K., van Gils J.M., Deng J., Halle A., et al. CD36 ligands promote sterile inflammation through assembly of a toll-like receptor 4 and 6 heterodimer. Nat Immunol 2010, 11:155-161.
    • (2010) Nat Immunol , vol.11 , pp. 155-161
    • Stewart, C.R.1    Stuart, L.M.2    Wilkinson, K.3    van Gils, J.M.4    Deng, J.5    Halle, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.