-
1
-
-
27644546807
-
Brain metastases: Epidemiology and pathophysiology
-
Gavrilovic, I. T. & Posner, J. B. Brain metastases: epidemiology and pathophysiology. J. Neurooncol. 75, 5-14 (2005).
-
(2005)
J. Neurooncol.
, vol.75
, pp. 5-14
-
-
Gavrilovic, I.T.1
Posner, J.B.2
-
2
-
-
76049128595
-
Estimates of cancer incidence and mortality in Europe in 2008
-
Ferlay, J., Parkin, D. M. & Steliarova-Foucher, E. Estimates of cancer incidence and mortality in Europe in 2008. Eur. J. Cancer 46, 765-781 (2010).
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 765-781
-
-
Ferlay, J.1
Parkin, D.M.2
Steliarova-Foucher, E.3
-
3
-
-
84929620816
-
CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2007-2011
-
Ostrom, Q. T. et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol. 16, iv1-iv63 (2014).
-
(2014)
Neuro Oncol.
, vol.16
, pp. iv1-iv63
-
-
Ostrom, Q.T.1
-
4
-
-
80052783811
-
Epidemiological study of primary intracranial tumors: A regional survey in Kumamoto prefecture in southern Japan - 20-year study
-
Nakamura, H., Makino, K., Yano, S., Kuratsu, J. & Kumamoto Brain Tumor Research Group. Epidemiological study of primary intracranial tumors: a regional survey in Kumamoto prefecture in southern Japan - 20-year study. Int. J. Clin. Oncol. 16, 314-321 (2011).
-
(2011)
Int. J. Clin. Oncol.
, vol.16
, pp. 314-321
-
-
Nakamura, H.1
Makino, K.2
Yano, S.3
Kuratsu, J.4
-
5
-
-
0024207655
-
The incidence of intracranial gliomas in southern Finland
-
Kallio, M. The incidence of intracranial gliomas in southern Finland. Acta Neurol. Scand. 78, 480-483 (1988).
-
(1988)
Acta Neurol. Scand.
, vol.78
, pp. 480-483
-
-
Kallio, M.1
-
6
-
-
53949091844
-
Brain tumor epidemiology: Consensus from the Brain Tumor Epidemiology Consortium
-
Bondy, M. L. et al. Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Cancer 113, 1953-1968 (2008).
-
(2008)
Cancer
, vol.113
, pp. 1953-1968
-
-
Bondy, M.L.1
-
9
-
-
0023741159
-
Tumors of the brain and nervous system after radiotherapy in childhood
-
Ron, E. et al. Tumors of the brain and nervous system after radiotherapy in childhood. N. Engl. J. Med. 319, 1033-1039 (1988).
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 1033-1039
-
-
Ron, E.1
-
10
-
-
15544375367
-
Long-term follow-up for brain tumor development after childhood exposure to ionizing radiation for tinea capitis
-
Sadetzki, S. et al. Long-term follow-up for brain tumor development after childhood exposure to ionizing radiation for tinea capitis. Radiat. Res. 163, 424-432 (2005).
-
(2005)
Radiat. Res.
, vol.163
, pp. 424-432
-
-
Sadetzki, S.1
-
11
-
-
33750591336
-
New primary neoplasms of the central nervous system in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study
-
Neglia, J. P. et al. New primary neoplasms of the central nervous system in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J. Natl Cancer Inst. 98, 1528-1537 (2006).
-
(2006)
J. Natl Cancer Inst.
, vol.98
, pp. 1528-1537
-
-
Neglia, J.P.1
-
12
-
-
0026506806
-
Risk of second brain tumour after conservative surgery and radiotherapy for pituitary adenoma
-
Brada, M. et al. Risk of second brain tumour after conservative surgery and radiotherapy for pituitary adenoma. BMJ 304, 1343-1346 (1992).
-
(1992)
BMJ
, vol.304
, pp. 1343-1346
-
-
Brada, M.1
-
13
-
-
14044257956
-
Risk of second brain tumor after conservative surgery and radiotherapy for pituitary adenoma: Update after an additional 10 years
-
Minniti, G., Traish, D., Ashley, S., Gonsalves, A. & Brada, M. Risk of second brain tumor after conservative surgery and radiotherapy for pituitary adenoma: update after an additional 10 years. J. Clin. Endocrinol. Metab. 90, 800-804 (2005).
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, pp. 800-804
-
-
Minniti, G.1
Traish, D.2
Ashley, S.3
Gonsalves, A.4
Brada, M.5
-
14
-
-
77953394987
-
Brain tumour risk in relation to mobile telephone use: Results of the INTERPHONE international case-control study
-
INTERPHONE Study Group. Brain tumour risk in relation to mobile telephone use: results of the INTERPHONE international case-control study. Int. J. Epidemiol. 39, 675-694 (2010).
-
(2010)
Int. J. Epidemiol.
, vol.39
, pp. 675-694
-
-
-
15
-
-
84902489371
-
The epidemiology of glioma in adults: A "state of the science" review
-
Ostrom, Q. T. et al. The epidemiology of glioma in adults: a "state of the science" review. Neuro Oncol. 16, 896-913 (2014).
-
(2014)
Neuro Oncol.
, vol.16
, pp. 896-913
-
-
Ostrom, Q.T.1
-
16
-
-
35548956467
-
Atopy and risk of brain tumors: A meta-analysis
-
Linos, E., Raine, T., Alonso, A. & Michaud, D. Atopy and risk of brain tumors: a meta-analysis. J. Natl Cancer Inst. 99, 1544-1550 (2007).
-
(2007)
J. Natl Cancer Inst.
, vol.99
, pp. 1544-1550
-
-
Linos, E.1
Raine, T.2
Alonso, A.3
Michaud, D.4
-
17
-
-
78649635096
-
Nervous system tumors associated with familial tumor syndromes
-
Ohgaki, H., Kim, Y. H. & Steinbach, J. P. Nervous system tumors associated with familial tumor syndromes. Curr. Opin. Neurol. 23, 583-591 (2010).
-
(2010)
Curr. Opin. Neurol.
, vol.23
, pp. 583-591
-
-
Ohgaki, H.1
Kim, Y.H.2
Steinbach, J.P.3
-
18
-
-
84930462553
-
Germline mutations in shelterin complex genes are associated with familial glioma
-
Bainbridge, M. N. et al. Germline mutations in shelterin complex genes are associated with familial glioma. J. Natl Cancer Inst. 107, 384 (2015).
-
(2015)
J. Natl Cancer Inst.
, vol.107
, pp. 384
-
-
Bainbridge, M.N.1
-
19
-
-
68149180890
-
Genome-wide association study identifies five susceptibility loci for glioma
-
Shete, S. et al. Genome-wide association study identifies five susceptibility loci for glioma. Nat. Genet. 41, 899-904 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 899-904
-
-
Shete, S.1
-
20
-
-
68149180891
-
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility
-
Wrensch, M. et al. Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nat. Genet. 41, 905-908 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 905-908
-
-
Wrensch, M.1
-
21
-
-
84866932650
-
A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation
-
Jenkins, R. B. et al. A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. Nat. Genet. 44, 1122-1125 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 1122-1125
-
-
Jenkins, R.B.1
-
22
-
-
84877146580
-
Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology
-
Rice, T. et al. Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology. Neuro Oncol. 15, 535-541 (2013).
-
(2013)
Neuro Oncol.
, vol.15
, pp. 535-541
-
-
Rice, T.1
-
23
-
-
80055009292
-
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
-
Stacey, S. N. et al. A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat. Genet. 43, 1098-1103 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 1098-1103
-
-
Stacey, S.N.1
-
24
-
-
77954513404
-
A comprehensive study of the association between the EGFR and ERBB2 genes and glioma risk
-
Andersson, U. et al. A comprehensive study of the association between the EGFR and ERBB2 genes and glioma risk. Acta Oncol. 49, 767-775 (2010).
-
(2010)
Acta Oncol.
, vol.49
, pp. 767-775
-
-
Andersson, U.1
-
25
-
-
84877898030
-
Deciphering the 8q24.21 association for glioma
-
Enciso-Mora, V. et al. Deciphering the 8q24.21 association for glioma. Hum. Mol. Genet. 22, 2293-2302 (2013).
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 2293-2302
-
-
Enciso-Mora, V.1
-
26
-
-
84904101984
-
Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk
-
Walsh, K. M. et al. Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. Nat. Genet. 46, 731-735 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 731-735
-
-
Walsh, K.M.1
-
27
-
-
84870988159
-
Genome-wide association study of glioma and meta-analysis
-
Rajaraman, P. et al. Genome-wide association study of glioma and meta-analysis. Hum. Genet. 131, 1877-1888 (2012).
-
(2012)
Hum. Genet.
, vol.131
, pp. 1877-1888
-
-
Rajaraman, P.1
-
28
-
-
0038711739
-
Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras
-
Yunoue, S. et al. Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras. J. Biol. Chem. 278, 26958-26969 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26958-26969
-
-
Yunoue, S.1
-
29
-
-
43049124130
-
BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas
-
Pfister, S. et al. BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas. J. Clin. Invest. 118, 1739-1749 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1739-1749
-
-
Pfister, S.1
-
30
-
-
55349107544
-
Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
-
Jones, D. T. et al. Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas. Cancer Res. 68, 8673-8677 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 8673-8677
-
-
Jones, D.T.1
-
31
-
-
84880983541
-
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
-
Jones, D. T. et al. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nat. Genet. 45, 927-932 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 927-932
-
-
Jones, D.T.1
-
32
-
-
84878723078
-
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
-
Zhang, J. et al. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat. Genet. 45, 602-612 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 602-612
-
-
Zhang, J.1
-
33
-
-
79953308458
-
An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice
-
Gronych, J. et al. An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice. J. Clin. Invest. 121, 1344-1348 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1344-1348
-
-
Gronych, J.1
-
34
-
-
85017267355
-
Selumetinib in treating young patients with recurrent or refractory low grade glioma
-
National Cancer Institute [online]
-
National Cancer Institute. Selumetinib in treating young patients with recurrent or refractory low grade glioma. ClinicalTrials.gov [online], https:// clinicaltrials.gov/ct2/show/NCT01089101 (2010).
-
(2010)
ClinicalTrials.gov
-
-
-
35
-
-
79960397029
-
Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas
-
Jacob, K. et al. Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas. Clin. Cancer Res. 17, 4650-4660 (2011).
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 4650-4660
-
-
Jacob, K.1
-
36
-
-
79957880389
-
BRAF activation induces transformation and then senescence in human neural stem cells: A pilocytic astrocytoma model
-
Raabe, E. H. et al. BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. Clin. Cancer Res. 17, 3590-3599 (2011).
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 3590-3599
-
-
Raabe, E.H.1
-
37
-
-
79954441895
-
Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
-
Schindler, G. et al. Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. Acta Neuropathol. 121, 397-405 (2011).
-
(2011)
Acta Neuropathol.
, vol.121
, pp. 397-405
-
-
Schindler, G.1
-
38
-
-
33847053161
-
Frequent loss of chromosome 9, homozygous CDKN2A/p14ARF/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas
-
Weber, R. G. et al. Frequent loss of chromosome 9, homozygous CDKN2A/p14ARF/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas. Oncogene 26, 1088-1097 (2007).
-
(2007)
Oncogene
, vol.26
, pp. 1088-1097
-
-
Weber, R.G.1
-
39
-
-
84898540842
-
BRAF-mutated pleomorphic xanthoastrocytoma is associated with temporal location, reticulin fiber deposition and CD34 expression
-
Koelsche, C. et al. BRAF-mutated pleomorphic xanthoastrocytoma is associated with temporal location, reticulin fiber deposition and CD34 expression. Brain Pathol. 24, 221-229 (2014).
-
(2014)
Brain Pathol.
, vol.24
, pp. 221-229
-
-
Koelsche, C.1
-
40
-
-
75149150689
-
Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation
-
Robinson, J. P. et al. Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation. Oncogene 29, 335-344 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 335-344
-
-
Robinson, J.P.1
-
41
-
-
84861918640
-
Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy
-
Huillard, E. et al. Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. Proc. Natl Acad. Sci. USA 109, 8710-8715 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 8710-8715
-
-
Huillard, E.1
-
42
-
-
10044259616
-
Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: Biallelic inactivation of TSC1 or TSC2 leads to mTOR activation
-
Chan, J. A. et al. Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation. J. Neuropathol. Exp. Neurol. 63, 1236-1242 (2004).
-
(2004)
J. Neuropathol. Exp. Neurol.
, vol.63
, pp. 1236-1242
-
-
Chan, J.A.1
-
43
-
-
80051495791
-
Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle
-
Zhou, J. et al. Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle. Genes Dev. 25, 1595-1600 (2011).
-
(2011)
Genes Dev.
, vol.25
, pp. 1595-1600
-
-
Zhou, J.1
-
44
-
-
78049510428
-
Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis
-
Krueger, D. A. et al. Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis. N. Engl. J. Med. 363, 1801-1811 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1801-1811
-
-
Krueger, D.A.1
-
45
-
-
84925231101
-
Everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: 2-year open-label extension of the randomised EXIST-1 study
-
Franz, D. N. et al. Everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: 2-year open-label extension of the randomised EXIST-1 study. Lancet Oncol. 15, 1513-1520 (2014).
-
(2014)
Lancet Oncol.
, vol.15
, pp. 1513-1520
-
-
Franz, D.N.1
-
46
-
-
84919921568
-
Farewell to oligoastrocytoma: In situ molecular genetics favor classification as either oligodendroglioma or astrocytoma
-
Sahm, F. et al. Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma. Acta Neuropathol. 128, 551-559 (2014).
-
(2014)
Acta Neuropathol.
, vol.128
, pp. 551-559
-
-
Sahm, F.1
-
47
-
-
84904247565
-
Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas
-
Killela, P. J. et al. Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas. Oncotarget 5, 1515-1525 (2014).
-
(2014)
Oncotarget
, vol.5
, pp. 1515-1525
-
-
Killela, P.J.1
-
48
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan, H. et al. IDH1 and IDH2 mutations in gliomas. N. Engl. J. Med. 360, 765-773 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 765-773
-
-
Yan, H.1
-
49
-
-
56749156414
-
Analysis of the IDH1 codon 132 mutation in brain tumors
-
Balss, J. et al. Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol. 116, 597-602 (2008).
-
(2008)
Acta Neuropathol.
, vol.116
, pp. 597-602
-
-
Balss, J.1
-
50
-
-
67349220062
-
Selective acquisition of IDH1 R132C mutations in astrocytomas associated with Li-Fraumeni syndrome
-
Watanabe, T., Vital, A., Nobusawa, S., Kleihues, P. & Ohgaki, H. Selective acquisition of IDH1 R132C mutations in astrocytomas associated with Li-Fraumeni syndrome. Acta Neuropathol. 117, 653-656 (2009).
-
(2009)
Acta Neuropathol.
, vol.117
, pp. 653-656
-
-
Watanabe, T.1
Vital, A.2
Nobusawa, S.3
Kleihues, P.4
Ohgaki, H.5
-
51
-
-
77954697566
-
Isocitrate dehydrogenase 1 and 2 mutations in cancer: Alterations at a crossroads of cellular metabolism
-
Reitman, Z. J. & Yan, H. Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. J. Natl Cancer Inst. 102, 932-941 (2010).
-
(2010)
J. Natl Cancer Inst.
, vol.102
, pp. 932-941
-
-
Reitman, Z.J.1
Yan, H.2
-
52
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases
-
Xu, W. et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell 19, 17-30 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 17-30
-
-
Xu, W.1
-
53
-
-
84858796263
-
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
-
Turcan, S. et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 483, 479-483 (2012).
-
(2012)
Nature
, vol.483
, pp. 479-483
-
-
Turcan, S.1
-
54
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
Noushmehr, H. et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 17, 510-522 (2010).
-
(2010)
Cancer Cell
, vol.17
, pp. 510-522
-
-
Noushmehr, H.1
-
55
-
-
84866480031
-
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function
-
Sasaki, M. et al. D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 26, 2038-2049 (2012).
-
(2012)
Genes Dev.
, vol.26
, pp. 2038-2049
-
-
Sasaki, M.1
-
56
-
-
80052608062
-
Mutations in CIC and FUBP1 contribute to human oligodendroglioma
-
Bettegowda, C. et al. Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science 333, 1453-1455 (2011).
-
(2011)
Science
, vol.333
, pp. 1453-1455
-
-
Bettegowda, C.1
-
57
-
-
84866411339
-
CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas
-
Sahm, F. et al. CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas. Acta Neuropathol. 123, 853-860 (2012).
-
(2012)
Acta Neuropathol.
, vol.123
, pp. 853-860
-
-
Sahm, F.1
-
58
-
-
0029736825
-
Characterization of genomic alterations associated with glioma progression by comparative genomic hybridization
-
Weber, R. G. et al. Characterization of genomic alterations associated with glioma progression by comparative genomic hybridization. Oncogene 13, 983-994 (1996).
-
(1996)
Oncogene
, vol.13
, pp. 983-994
-
-
Weber, R.G.1
-
59
-
-
4944255253
-
Genetic pathways to glioblastoma: A population-based study
-
Ohgaki, H. et al. Genetic pathways to glioblastoma: a population-based study. Cancer Res. 64, 6892-6899 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 6892-6899
-
-
Ohgaki, H.1
-
60
-
-
84875113616
-
A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1
-
Klink, B. et al. A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1. PLoS ONE 8, e59773 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e59773
-
-
Klink, B.1
-
61
-
-
78650261624
-
Oligodendroglioma cell lines containing t(1;19)(q10;p10)
-
Kelly, J. J. et al. Oligodendroglioma cell lines containing t(1;19)(q10;p10). Neuro Oncol. 12, 745-755 (2010).
-
(2010)
Neuro Oncol.
, vol.12
, pp. 745-755
-
-
Kelly, J.J.1
-
62
-
-
84859553853
-
An in vivo patient-derived model of endogenous IDH1-mutant glioma
-
Luchman, H. A. et al. An in vivo patient-derived model of endogenous IDH1-mutant glioma. Neuro Oncol. 14, 184-191 (2012).
-
(2012)
Neuro Oncol.
, vol.14
, pp. 184-191
-
-
Luchman, H.A.1
-
63
-
-
84877632013
-
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
-
Rohle, D. et al. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science 340, 626-630 (2013).
-
(2013)
Science
, vol.340
, pp. 626-630
-
-
Rohle, D.1
-
64
-
-
84877866746
-
Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1
-
Ramkissoon, L. A. et al. Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. Proc. Natl Acad. Sci. USA 110, 8188-8193 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 8188-8193
-
-
Ramkissoon, L.A.1
-
65
-
-
84867606428
-
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
-
Sturm, D. et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 22, 425-437 (2012).
-
(2012)
Cancer Cell
, vol.22
, pp. 425-437
-
-
Sturm, D.1
-
66
-
-
84917692890
-
Molecular pathways in gliomagenesis and their relevance to neuropathologic diagnosis
-
Appin, C. L. & Brat, D. J. Molecular pathways in gliomagenesis and their relevance to neuropathologic diagnosis. Adv. Anat. Pathol. 22, 50-58 (2015).
-
(2015)
Adv. Anat. Pathol.
, vol.22
, pp. 50-58
-
-
Appin, C.L.1
Brat, D.J.2
-
67
-
-
84885074034
-
The somatic genomic landscape of glioblastoma
-
Brennan, C. W. et al. The somatic genomic landscape of glioblastoma. Cell 155, 462-477 (2013).
-
(2013)
Cell
, vol.155
, pp. 462-477
-
-
Brennan, C.W.1
-
68
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455, 1061-1068 (2008).
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
69
-
-
0026446102
-
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
-
Plate, K. H., Breier, G., Weich, H. A. & Risau, W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359, 845-848 (1992).
-
(1992)
Nature
, vol.359
, pp. 845-848
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
Risau, W.4
-
70
-
-
84925596863
-
Transforming growth factor-β pathway activity in glioblastoma
-
Frei, K. et al. Transforming growth factor-β pathway activity in glioblastoma. Oncotarget 6, 5963-5977 (2015).
-
(2015)
Oncotarget
, vol.6
, pp. 5963-5977
-
-
Frei, K.1
-
71
-
-
84899526966
-
The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
-
Wu, G. et al. The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. Nat. Genet. 46, 444-450 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 444-450
-
-
Wu, G.1
-
72
-
-
84899570180
-
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
-
Buczkowicz, P. et al. Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations. Nat. Genet. 46, 451-456 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 451-456
-
-
Buczkowicz, P.1
-
73
-
-
84961291627
-
Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma
-
Hashizume, R. et al. Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma. Nat. Med. 20, 1394-1396 (2014).
-
(2014)
Nat. Med.
, vol.20
, pp. 1394-1396
-
-
Hashizume, R.1
-
74
-
-
0032801037
-
Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas
-
Ebert, C. et al. Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas. Am. J. Pathol. 155, 627-632 (1999).
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 627-632
-
-
Ebert, C.1
-
75
-
-
84896721467
-
C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma
-
Parker, M. et al. C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma. Nature 506, 451-455 (2014).
-
(2014)
Nature
, vol.506
, pp. 451-455
-
-
Parker, M.1
-
76
-
-
84896739200
-
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
-
Mack, S. C. et al. Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Nature 506, 445-450 (2014).
-
(2014)
Nature
, vol.506
, pp. 445-450
-
-
Mack, S.C.1
-
77
-
-
84862644933
-
A prognostic gene expression signature in infratentorial ependymoma
-
Wani, K. et al. A prognostic gene expression signature in infratentorial ependymoma. Acta Neuropathol. 123, 727-738 (2012).
-
(2012)
Acta Neuropathol.
, vol.123
, pp. 727-738
-
-
Wani, K.1
-
78
-
-
80051580421
-
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma
-
Witt, H. et al. Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell 20, 143-157 (2011).
-
(2011)
Cancer Cell
, vol.20
, pp. 143-157
-
-
Witt, H.1
-
79
-
-
84929178049
-
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups
-
Pajtler, K. W. et al. Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups. Cancer Cell 27, 728-743 (2015).
-
(2015)
Cancer Cell
, vol.27
, pp. 728-743
-
-
Pajtler, K.W.1
-
80
-
-
80052714649
-
Molecular imaging of gliomas with PET: Opportunities and limitations
-
la Fougère, C., Suchorska, B., Bartenstein, P., Kreth, F. W. & Tonn, J. C. Molecular imaging of gliomas with PET: opportunities and limitations. Neuro Oncol. 13, 806-819 (2011).
-
(2011)
Neuro Oncol.
, vol.13
, pp. 806-819
-
-
La Fougère, C.1
Suchorska, B.2
Bartenstein, P.3
Kreth, F.W.4
Tonn, J.C.5
-
81
-
-
34347207046
-
-
World Health Organization. eds Louis, D. N., Ohgaki, H., Wiestler, O. D. & Cavenee, W. K. WHO Publications
-
World Health Organization. WHO Classification of Tumours of the Central Nervous System (eds Louis, D. N., Ohgaki, H., Wiestler, O. D. & Cavenee, W. K.) (WHO Publications, 2007)
-
(2007)
WHO Classification of Tumours of the Central Nervous System
-
-
-
82
-
-
84880791777
-
Molecular neuro-oncology in clinical practice: A new horizon
-
Weller, M. et al. Molecular neuro-oncology in clinical practice: a new horizon. Lancet Oncol. 14, e370-e379 (2013).
-
(2013)
Lancet Oncol.
, vol.14
, pp. e370-e379
-
-
Weller, M.1
-
83
-
-
84904902698
-
EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma
-
Weller, M. et al. EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma. Lancet Oncol. 15, e395-e403 (2014).
-
(2014)
Lancet Oncol.
, vol.15
, pp. e395-e403
-
-
Weller, M.1
-
84
-
-
84904419561
-
Molecular stereotactic biopsy technique improves diagnostic accuracy and enables personalized treatment strategies in glioma patients
-
Eigenbrod, S. et al. Molecular stereotactic biopsy technique improves diagnostic accuracy and enables personalized treatment strategies in glioma patients. Acta Neurochir. (Wien) 156, 1427-1440 (2014).
-
(2014)
Acta Neurochir. (Wien)
, vol.156
, pp. 1427-1440
-
-
Eigenbrod, S.1
-
85
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons, D. W. et al. An integrated genomic analysis of human glioblastoma multiforme. Science 321, 1807-1812 (2008).
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
-
86
-
-
84874091180
-
The definition of primary and secondary glioblastoma
-
Ohgaki, H. & Kleihues, P. The definition of primary and secondary glioblastoma. Clin. Cancer Res. 19, 764-772 (2013).
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 764-772
-
-
Ohgaki, H.1
Kleihues, P.2
-
87
-
-
70449518400
-
Monoclonal antibody specific for IDH1 R132H mutation
-
Capper, D., Zentgraf, H., Balss, J., Hartmann, C. & von Deimling, A. Monoclonal antibody specific for IDH1 R132H mutation. Acta Neuropathol. 118, 599-601 (2009).
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 599-601
-
-
Capper, D.1
Zentgraf, H.2
Balss, J.3
Hartmann, C.4
Von Deimling, A.5
-
88
-
-
77953028158
-
Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing
-
Felsberg, J. et al. Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing. Acta Neuropathol. 119, 501-507 (2010).
-
(2010)
Acta Neuropathol.
, vol.119
, pp. 501-507
-
-
Felsberg, J.1
-
89
-
-
84929712325
-
ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma
-
Reuss, D. E. et al. ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma. Acta Neuropathol. 129, 133-146 (2015).
-
(2015)
Acta Neuropathol.
, vol.129
, pp. 133-146
-
-
Reuss, D.E.1
-
90
-
-
84868019401
-
Personalized care in neuro-oncology coming of age: Why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice
-
Weller, M. et al. Personalized care in neuro-oncology coming of age: why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice. Neuro Oncol. 14, iv100-iv108 (2012).
-
(2012)
Neuro Oncol.
, vol.14
, pp. iv100-iv108
-
-
Weller, M.1
-
91
-
-
75149166496
-
MGMT promoter methylation in malignant gliomas: Ready for personalized medicine?
-
Weller, M. et al. MGMT promoter methylation in malignant gliomas: ready for personalized medicine? Nat. Rev. Neurol. 6, 39-51 (2010).
-
(2010)
Nat. Rev. Neurol.
, vol.6
, pp. 39-51
-
-
Weller, M.1
-
92
-
-
84904070681
-
MGMT testing - The challenges for biomarker-based glioma treatment
-
Wick, W. et al. MGMT testing - the challenges for biomarker-based glioma treatment. Nat. Rev. Neurol. 10, 372-385 (2014).
-
(2014)
Nat. Rev. Neurol.
, vol.10
, pp. 372-385
-
-
Wick, W.1
-
93
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi, M. E. et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N. Engl. J. Med. 352, 997-1003 (2005).
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
-
94
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp, R. et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 10, 459-466 (2009).
-
(2009)
Lancet Oncol.
, vol.10
, pp. 459-466
-
-
Stupp, R.1
-
95
-
-
84865558322
-
Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: The Nordic randomised, phase 3 trial
-
Malmstrom, A. et al. Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial. Lancet Oncol. 13, 916-926 (2012).
-
(2012)
Lancet Oncol.
, vol.13
, pp. 916-926
-
-
Malmstrom, A.1
-
96
-
-
84863091424
-
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: The NOA-08 randomised, phase 3 trial
-
Wick, W. et al. Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial. Lancet Oncol. 13, 707-715 (2012).
-
(2012)
Lancet Oncol.
, vol.13
, pp. 707-715
-
-
Wick, W.1
-
97
-
-
84866542816
-
MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status
-
Bady, P. et al. MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status. Acta Neuropathol. 124, 547-560 (2012).
-
(2012)
Acta Neuropathol.
, vol.124
, pp. 547-560
-
-
Bady, P.1
-
98
-
-
84927177508
-
TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations
-
Labussiere, M. et al. TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations. Br. J. Cancer 111, 2024-2032 (2014).
-
(2014)
Br. J. Cancer
, vol.111
, pp. 2024-2032
-
-
Labussiere, M.1
-
99
-
-
84888229904
-
Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation
-
Wick, W. et al. Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation. Neurology 81, 1515-1522 (2013).
-
(2013)
Neurology
, vol.81
, pp. 1515-1522
-
-
Wick, W.1
-
100
-
-
84939952838
-
Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome-and transcriptome-wide profiling improves stratification of prognostically distinct patient groups
-
Weller, M. et al. Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome-and transcriptome-wide profiling improves stratification of prognostically distinct patient groups. Acta Neuropathol. 129, 679-693 (2015).
-
(2015)
Acta Neuropathol.
, vol.129
, pp. 679-693
-
-
Weller, M.1
-
101
-
-
84929129626
-
Mutational landscape and clonal architecture in grade II and III gliomas
-
Suzuki, H. et al. Mutational landscape and clonal architecture in grade II and III gliomas. Nat. Genet. 47, 458-468 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 458-468
-
-
Suzuki, H.1
-
102
-
-
84932628860
-
A comprehensive, integrative genomic analysis of diffuse lower-grade gliomas study of ICT-107 immunotherapy in glioblastoma multiforme (GBM)
-
The Cancer Genome Atlas Research Network
-
The Cancer Genome Atlas Research Network. A comprehensive, integrative genomic analysis of diffuse lower-grade gliomas study of ICT-107 immunotherapy in glioblastoma multiforme (GBM). N. Engl. J. Med. 372, 2481-2498 (2015).
-
(2015)
N. Engl. J. Med.
, vol.372
, pp. 2481-2498
-
-
-
103
-
-
84932649039
-
Glioma groups based on 1p/19q, IDH, and TERT promoter mutations in tumors
-
Eckel-Passow, J. E. et al. Glioma groups based on 1p/19q, IDH, and TERT promoter mutations in tumors. N. Engl. J. Med. 372, 2499-2508 (2015).
-
(2015)
N. Engl. J. Med.
, vol.372
, pp. 2499-2508
-
-
Eckel-Passow, J.E.1
-
104
-
-
3042757984
-
Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance
-
Aldape, K. D. et al. Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance. J. Neuropathol. Exp. Neurol. 63, 700-707 (2004).
-
(2004)
J. Neuropathol. Exp. Neurol.
, vol.63
, pp. 700-707
-
-
Aldape, K.D.1
-
105
-
-
84870065591
-
Epidermal growth factor receptor: A re-emerging target in glioblastoma
-
Hegi, M. E., Rajakannu, P. & Weller, M. Epidermal growth factor receptor: a re-emerging target in glioblastoma. Curr. Opin. Neurol. 25, 774-779 (2012).
-
(2012)
Curr. Opin. Neurol.
, vol.25
, pp. 774-779
-
-
Hegi, M.E.1
Rajakannu, P.2
Weller, M.3
-
106
-
-
78149254368
-
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
-
Sampson, J. H. et al. Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. J. Clin. Oncol. 28, 4722-4729 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 4722-4729
-
-
Sampson, J.H.1
-
107
-
-
68349088073
-
Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma
-
Korshunov, A. et al. Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma. Acta Neuropathol. 118, 401-405 (2009).
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 401-405
-
-
Korshunov, A.1
-
108
-
-
82955249323
-
Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas
-
Tian, Y. et al. Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas. J. Mol. Diagn. 13, 669-677 (2011).
-
(2011)
J. Mol. Diagn.
, vol.13
, pp. 669-677
-
-
Tian, Y.1
-
109
-
-
84655167688
-
BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants
-
Lin, A. et al. BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants. J. Neuropathol. Exp. Neurol. 71, 66-72 (2012).
-
(2012)
J. Neuropathol. Exp. Neurol.
, vol.71
, pp. 66-72
-
-
Lin, A.1
-
110
-
-
79959580390
-
Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody
-
Capper, D. et al. Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody. Acta Neuropathol. 122, 11-19 (2011).
-
(2011)
Acta Neuropathol.
, vol.122
, pp. 11-19
-
-
Capper, D.1
-
111
-
-
79958744743
-
Screening for symptomatic optic pathway glioma in children with neurofibromatosis type 1
-
author reply 818-819
-
Gutmann, D. H., Listernick, R. & Ferner, R. E. Screening for symptomatic optic pathway glioma in children with neurofibromatosis type 1. Eye (Lond.) 25, 818; author reply 818-819 (2011).
-
(2011)
Eye (Lond.)
, vol.25
, pp. 818
-
-
Gutmann, D.H.1
Listernick, R.2
Ferner, R.E.3
-
112
-
-
84902163692
-
Silent diffuse low-grade glioma: Toward screening and preventive treatment?
-
Mandonnet, E. et al. Silent diffuse low-grade glioma: toward screening and preventive treatment? Cancer 120, 1758-1762 (2014).
-
(2014)
Cancer
, vol.120
, pp. 1758-1762
-
-
Mandonnet, E.1
-
113
-
-
35748975181
-
Incidental findings on brain MRI in the general population
-
Vernooij, M. W. et al. Incidental findings on brain MRI in the general population. N. Engl. J. Med. 357, 1821-1828 (2007).
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 1821-1828
-
-
Vernooij, M.W.1
-
114
-
-
84856114191
-
Application of novel response/ progression measures for surgically delivered therapies for gliomas: Response Assessment in Neuro-Oncology (RANO) Working Group
-
discussion 243-244
-
Vogelbaum, M. A. et al. Application of novel response/ progression measures for surgically delivered therapies for gliomas: Response Assessment in Neuro-Oncology (RANO) Working Group. Neurosurgery 70, 234-243; discussion 243-244 (2012).
-
(2012)
Neurosurgery
, vol.70
, pp. 234-243
-
-
Vogelbaum, M.A.1
-
115
-
-
77951625266
-
Updated response assessment criteria for high-grade gliomas: Response Assessment in Neuro-Oncology Working Group
-
Wen, P. Y. et al. Updated response assessment criteria for high-grade gliomas: Response Assessment in Neuro-Oncology Working Group. J. Clin. Oncol. 28, 1963-1972 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 1963-1972
-
-
Wen, P.Y.1
-
116
-
-
79956061552
-
Response Assessment in Neuro-Oncology criteria: Implementation challenges in multicenter neuro-oncology trials
-
Pope, W. B. & Hessel, C. Response Assessment in Neuro-Oncology criteria: implementation challenges in multicenter neuro-oncology trials. AJNR Am. J. Neuroradiol. 32, 794-797 (2011).
-
(2011)
AJNR Am. J. Neuroradiol.
, vol.32
, pp. 794-797
-
-
Pope, W.B.1
Hessel, C.2
-
117
-
-
84455185238
-
Pseudoprogression and pseudoresponse: Imaging challenges in the assessment of posttreatment glioma
-
Hygino da Cruz, L. C. Jr et al. Pseudoprogression and pseudoresponse: imaging challenges in the assessment of posttreatment glioma. AJNR Am. J. Neuroradiol. 32, 1978-1985 (2011).
-
(2011)
AJNR Am. J. Neuroradiol.
, vol.32
, pp. 1978-1985
-
-
Hygino da Cruz, L.C.1
-
118
-
-
84875175029
-
Response assessment criteria for glioblastoma: Practical adaptation and implementation in clinical trials of antiangiogenic therapy
-
Chinot, O. L. et al. Response assessment criteria for glioblastoma: practical adaptation and implementation in clinical trials of antiangiogenic therapy. Curr. Neurol. Neurosci. Rep. 13, 347 (2013).
-
(2013)
Curr. Neurol. Neurosci. Rep.
, vol.13
, pp. 347
-
-
Chinot, O.L.1
-
119
-
-
84878129123
-
Comparison of susceptibility weighted imaging and TOF-angiography for the detection of thrombi in acute stroke
-
Radbruch, A. et al. Comparison of susceptibility weighted imaging and TOF-angiography for the detection of thrombi in acute stroke. PLoS ONE 8, e63459 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e63459
-
-
Radbruch, A.1
-
120
-
-
84906855037
-
Primary central nervous system lymphoma and atypical glioblastoma: Multiparametric differentiation by using diffusion-, perfusion-, and susceptibility-weighted MR imaging
-
Kickingereder, P. et al. Primary central nervous system lymphoma and atypical glioblastoma: multiparametric differentiation by using diffusion-, perfusion-, and susceptibility-weighted MR imaging. Radiology 272, 843-850 (2014).
-
(2014)
Radiology
, vol.272
, pp. 843-850
-
-
Kickingereder, P.1
-
121
-
-
84898435813
-
Pretreatment ADC histogram analysis is a predictive imaging biomarker for bevacizumab treatment but not chemotherapy in recurrent glioblastoma
-
Ellingson, B. M. et al. Pretreatment ADC histogram analysis is a predictive imaging biomarker for bevacizumab treatment but not chemotherapy in recurrent glioblastoma. AJNR Am. J. Neuroradiol. 35, 673-679 (2014).
-
(2014)
AJNR Am. J. Neuroradiol.
, vol.35
, pp. 673-679
-
-
Ellingson, B.M.1
-
122
-
-
84862098770
-
Comparison between intensity normalization techniques for dynamic susceptibility contrast (DSC)-MRI estimates of cerebral blood volume (CBV) in human gliomas
-
Ellingson, B. M. et al. Comparison between intensity normalization techniques for dynamic susceptibility contrast (DSC)-MRI estimates of cerebral blood volume (CBV) in human gliomas. J. Magn. Reson. Imaging 35, 1472-1477 (2012).
-
(2012)
J. Magn. Reson. Imaging
, vol.35
, pp. 1472-1477
-
-
Ellingson, B.M.1
-
123
-
-
78649632130
-
Steroids in neurooncology: Actions, indications, side-effects
-
Roth, P., Wick, W. & Weller, M. Steroids in neurooncology: actions, indications, side-effects. Curr. Opin. Neurol. 23, 597-602 (2010).
-
(2010)
Curr. Opin. Neurol.
, vol.23
, pp. 597-602
-
-
Roth, P.1
Wick, W.2
Weller, M.3
-
124
-
-
84865568082
-
Epilepsy meets cancer: When, why, and what to do about it?
-
Weller, M., Stupp, R. & Wick, W. Epilepsy meets cancer: when, why, and what to do about it? Lancet Oncol. 13, e375-e382 (2012).
-
(2012)
Lancet Oncol.
, vol.13
, pp. e375-e382
-
-
Weller, M.1
Stupp, R.2
Wick, W.3
-
125
-
-
84921596103
-
Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas
-
Karajannis, M. A. et al. Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas. Neuro Oncol. 16, 1408-1416 (2014).
-
(2014)
Neuro Oncol.
, vol.16
, pp. 1408-1416
-
-
Karajannis, M.A.1
-
126
-
-
84873653141
-
Everolimus long-term safety and efficacy in subependymal giant cell astrocytoma
-
Krueger, D. A. et al. Everolimus long-term safety and efficacy in subependymal giant cell astrocytoma. Neurology 80, 574-580 (2013).
-
(2013)
Neurology
, vol.80
, pp. 574-580
-
-
Krueger, D.A.1
-
127
-
-
84885059781
-
Salvage therapy with BRAF inhibitors for recurrent pleomorphic xanthoastrocytoma: A retrospective case series
-
Chamberlain, M. C. Salvage therapy with BRAF inhibitors for recurrent pleomorphic xanthoastrocytoma: a retrospective case series. J. Neurooncol. 114, 237-240 (2013).
-
(2013)
J. Neurooncol.
, vol.114
, pp. 237-240
-
-
Chamberlain, M.C.1
-
128
-
-
84963593691
-
Successful treatment of a progressive BRAF V600E-mutated anaplastic pleomorphic xanthoastrocytoma with vemurafenib monotherapy
-
Lee, E. Q., Ruland, S., LeBoeuf, N. R., Wen, P. Y. & Santagata, S. Successful treatment of a progressive BRAF V600E-mutated anaplastic pleomorphic xanthoastrocytoma with vemurafenib monotherapy. J. Clin. Oncol. http://dx.doi.org/10.1200/ JCO.2013.51.1766 (2014).
-
(2014)
J. Clin. Oncol.
-
-
Lee, E.Q.1
Ruland, S.2
LeBoeuf, N.R.3
Wen, P.Y.4
Santagata, S.5
-
129
-
-
34249915554
-
Panel review of anaplastic oligodendroglioma from European Organization for Research and Treatment of Cancer Trial 26951: Assessment of consensus in diagnosis, influence of 1p/19q loss, and correlations with outcome
-
Kros, J. M. et al. Panel review of anaplastic oligodendroglioma from European Organization for Research and Treatment of Cancer Trial 26951: assessment of consensus in diagnosis, influence of 1p/19q loss, and correlations with outcome. J. Neuropathol. Exp. Neurol. 66, 545-551 (2007).
-
(2007)
J. Neuropathol. Exp. Neurol.
, vol.66
, pp. 545-551
-
-
Kros, J.M.1
-
130
-
-
14744272782
-
Survival rates in patients with low-grade glioma after intraoperative magnetic resonance image guidance
-
Claus, E. B. et al. Survival rates in patients with low-grade glioma after intraoperative magnetic resonance image guidance. Cancer 103, 1227-1233 (2005).
-
(2005)
Cancer
, vol.103
, pp. 1227-1233
-
-
Claus, E.B.1
-
131
-
-
38949200071
-
Seizure characteristics and control following resection in 332 patients with low-grade gliomas
-
Chang, E. F. et al. Seizure characteristics and control following resection in 332 patients with low-grade gliomas. J. Neurosurg. 108, 227-235 (2008).
-
(2008)
J. Neurosurg.
, vol.108
, pp. 227-235
-
-
Chang, E.F.1
-
132
-
-
84893825333
-
Epileptic seizures in diffuse low-grade gliomas in adults
-
Pallud, J. et al. Epileptic seizures in diffuse low-grade gliomas in adults. Brain 137, 449-462 (2014).
-
(2014)
Brain
, vol.137
, pp. 449-462
-
-
Pallud, J.1
-
133
-
-
84864056416
-
Impact of intraoperative stimulation brain mapping on glioma surgery outcome: A meta-analysis
-
De Witt Hamer, P. C., Robles, S. G., Zwinderman, A. H., Duffau, H. & Berger, M. S. Impact of intraoperative stimulation brain mapping on glioma surgery outcome: a meta-analysis. J. Clin. Oncol. 30, 2559-2565 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 2559-2565
-
-
De Witt Hamer, P.C.1
Robles, S.G.2
Zwinderman, A.H.3
Duffau, H.4
Berger, M.S.5
-
134
-
-
41649090186
-
Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas
-
Smith, J. S. et al. Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas. J. Clin. Oncol. 26, 1338-1345 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 1338-1345
-
-
Smith, J.S.1
-
135
-
-
84870946553
-
Low-grade glioma surgery in eloquent areas: Volumetric analysis of extent of resection and its impact on overall survival. A single-institution experience in 190 patients: Clinical article
-
Ius, T. et al. Low-grade glioma surgery in eloquent areas: volumetric analysis of extent of resection and its impact on overall survival. A single-institution experience in 190 patients: clinical article. J. Neurosurg. 117, 1039-1052 (2012).
-
(2012)
J. Neurosurg.
, vol.117
, pp. 1039-1052
-
-
Ius, T.1
-
136
-
-
84868667212
-
Comparison of a strategy favoring early surgical resection versus a strategy favoring watchful waiting in low-grade gliomas
-
Jakola, A. S. et al. Comparison of a strategy favoring early surgical resection versus a strategy favoring watchful waiting in low-grade gliomas. JAMA 308, 1881-1888 (2012).
-
(2012)
JAMA
, vol.308
, pp. 1881-1888
-
-
Jakola, A.S.1
-
137
-
-
0037089635
-
Prognostic factors for survival in adult patients with cerebral low-grade glioma
-
Pignatti, F. et al. Prognostic factors for survival in adult patients with cerebral low-grade glioma. J. Clin. Oncol. 20, 2076-2084 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 2076-2084
-
-
Pignatti, F.1
-
138
-
-
79961129343
-
Validation of EORTC prognostic factors for adults with low-grade glioma: A report using intergroup 86-72-51
-
Daniels, T. B. et al. Validation of EORTC prognostic factors for adults with low-grade glioma: a report using intergroup 86-72-51. Int. J. Radiat. Oncol. Biol. Phys. 81, 218-224 (2011).
-
(2011)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.81
, pp. 218-224
-
-
Daniels, T.B.1
-
139
-
-
77955817286
-
Guidelines on management of low-grade gliomas: Report of an EFNS-EANO Task Force
-
Soffietti, R. et al. Guidelines on management of low-grade gliomas: report of an EFNS-EANO Task Force. Eur. J. Neurol. 17, 1124-1133 (2010).
-
(2010)
Eur. J. Neurol.
, vol.17
, pp. 1124-1133
-
-
Soffietti, R.1
-
140
-
-
24944439786
-
Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: The EORTC 22845 randomised trial
-
van den Bent, M. J. et al. Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial. Lancet 366, 985-990 (2005).
-
(2005)
Lancet
, vol.366
, pp. 985-990
-
-
Van Den Bent, M.J.1
-
141
-
-
84865785710
-
Randomized trial of radiation therapy plus procarbazine, lomustine, and vincristine chemotherapy for supratentorial adult low-grade glioma: Initial results of RTOG 9802
-
Shaw, E. G. et al. Randomized trial of radiation therapy plus procarbazine, lomustine, and vincristine chemotherapy for supratentorial adult low-grade glioma: initial results of RTOG 9802. J. Clin. Oncol. 30, 3065-3070 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 3065-3070
-
-
Shaw, E.G.1
-
142
-
-
84873345824
-
Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: Long-term follow-up of EORTC brain tumor group study 26951
-
van den Bent, M. J. et al. Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951. J. Clin. Oncol. 31, 344-350 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 344-350
-
-
Van Den Bent, M.J.1
-
143
-
-
84873338121
-
Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: Long-term results of RTOG 9402
-
Cairncross, G. et al. Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402. J. Clin. Oncol. 31, 337-343 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 337-343
-
-
Cairncross, G.1
-
144
-
-
84910149887
-
Temozolomide chemotherapy versus radiotherapy in molecularly characterized (1p loss) low-grade glioma: A randomized phase III intergroup study by the EORTC/NCIC-CTG/TROG/MRC-CTU (EORTC 22033-26033)
-
Baumert, B. G. et al. Temozolomide chemotherapy versus radiotherapy in molecularly characterized (1p loss) low-grade glioma: a randomized phase III intergroup study by the EORTC/NCIC-CTG/TROG/MRC-CTU (EORTC 22033-26033). J. Clin. Oncol. Abstr. 31, 2007 (2013).
-
(2013)
J. Clin. Oncol. Abstr.
, vol.31
, pp. 2007
-
-
Baumert, B.G.1
-
145
-
-
73349134695
-
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide
-
Wick, W. et al. NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. J. Clin. Oncol. 27, 5874-5880 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 5874-5880
-
-
Wick, W.1
-
146
-
-
85017248113
-
Radiation therapy with or without temozolomide in treating patients with anaplastic glioma
-
National Cancer Institute [online]
-
National Cancer Institute. Radiation therapy with or without temozolomide in treating patients with anaplastic glioma. ClinicalTrials.gov [online], https:// clinicaltrials.gov/ct2/show/NCT00626990?term= NCT00626990&rank=1 (2008).
-
(2008)
ClinicalTrials.gov
-
-
-
147
-
-
84886744421
-
Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT inhibitor decitabine
-
Turcan, S. et al. Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT inhibitor decitabine. Oncotarget 4, 1729-1736 (2013).
-
(2013)
Oncotarget
, vol.4
, pp. 1729-1736
-
-
Turcan, S.1
-
148
-
-
84857725402
-
Exploiting the mutanome for tumor vaccination
-
Castle, J. C. et al. Exploiting the mutanome for tumor vaccination. Cancer Res. 72, 1081-1091 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 1081-1091
-
-
Castle, J.C.1
-
149
-
-
84906557615
-
A vaccine targeting mutant IDH1 induces antitumour immunity
-
Schumacher, T. et al. A vaccine targeting mutant IDH1 induces antitumour immunity. Nature 512, 324-327 (2014).
-
(2014)
Nature
, vol.512
, pp. 324-327
-
-
Schumacher, T.1
-
150
-
-
84888300327
-
Immunological challenges for peptide-based immunotherapy in glioblastoma
-
Mohme, M., Neidert, M. C., Regli, L., Weller, M. & Martin, R. Immunological challenges for peptide-based immunotherapy in glioblastoma. Cancer Treat. Rev. 40, 248-258 (2014).
-
(2014)
Cancer Treat. Rev.
, vol.40
, pp. 248-258
-
-
Mohme, M.1
Neidert, M.C.2
Regli, L.3
Weller, M.4
Martin, R.5
-
151
-
-
84863006570
-
Immunotherapy for glioma: Promises and challenges
-
Han, S. J., Zygourakis, C., Lim, M. & Parsa, A. T. Immunotherapy for glioma: promises and challenges. Neurosurg. Clin. N. Am. 23, 357-370 (2012).
-
(2012)
Neurosurg. Clin. N. Am.
, vol.23
, pp. 357-370
-
-
Han, S.J.1
Zygourakis, C.2
Lim, M.3
Parsa, A.T.4
-
152
-
-
79960001570
-
An extent of resection threshold for newly diagnosed glioblastomas
-
Sanai, N., Polley, M. Y., McDermott, M. W., Parsa, A. T. & Berger, M. S. An extent of resection threshold for newly diagnosed glioblastomas. J. Neurosurg. 115, 3-8 (2011).
-
(2011)
J. Neurosurg.
, vol.115
, pp. 3-8
-
-
Sanai, N.1
Polley, M.Y.2
McDermott, M.W.3
Parsa, A.T.4
Berger, M.S.5
-
153
-
-
33645986455
-
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: A randomised controlled multicentre phase III trial
-
Stummer, W. et al. Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol. 7, 392-401 (2006).
-
(2006)
Lancet Oncol.
, vol.7
, pp. 392-401
-
-
Stummer, W.1
-
154
-
-
42449087356
-
Extent of resection and survival in glioblastoma multiforme: Identification of and adjustment for bias
-
discussion 564-576
-
Stummer, W. et al. Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias. Neurosurgery 62, 564-576; discussion 564-576 (2008).
-
(2008)
Neurosurgery
, vol.62
, pp. 564-576
-
-
Stummer, W.1
-
155
-
-
84891785971
-
Dose-dense temozolomide for newly diagnosed glioblastoma: A randomized phase III clinical trial
-
Gilbert, M. R. et al. Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial. J. Clin. Oncol. 31, 4085-4091 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 4085-4091
-
-
Gilbert, M.R.1
-
156
-
-
84908563697
-
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): A multicentre, randomised, open-label, phase 3 trial
-
Stupp, R. et al. Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol. 15, 1100-1108 (2014).
-
(2014)
Lancet Oncol.
, vol.15
, pp. 1100-1108
-
-
Stupp, R.1
-
157
-
-
84894114159
-
A randomized trial of bevacizumab for newly diagnosed glioblastoma
-
Gilbert, M. R. et al. A randomized trial of bevacizumab for newly diagnosed glioblastoma. N. Engl. J. Med. 370, 699-708 (2014).
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 699-708
-
-
Gilbert, M.R.1
-
158
-
-
84894194756
-
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma
-
Chinot, O. L. et al. Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma. N. Engl. J. Med. 370, 709-722 (2014).
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 709-722
-
-
Chinot, O.L.1
-
159
-
-
23144452287
-
High failure rate in spinal ependymomas with long-term follow-up
-
Gomez, D. R. et al. High failure rate in spinal ependymomas with long-term follow-up. Neuro Oncol. 7, 254-259 (2005).
-
(2005)
Neuro Oncol.
, vol.7
, pp. 254-259
-
-
Gomez, D.R.1
-
160
-
-
4143069338
-
Preliminary results from a phase II trial of conformal radiation therapy and evaluation of radiation-related CNS effects for pediatric patients with localized ependymoma
-
Merchant, T. E. et al. Preliminary results from a phase II trial of conformal radiation therapy and evaluation of radiation-related CNS effects for pediatric patients with localized ependymoma. J. Clin. Oncol. 22, 3156-3162 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 3156-3162
-
-
Merchant, T.E.1
-
161
-
-
0033958949
-
Combined postoperative irradiation and chemotherapy for anaplastic ependymomas in childhood: Results of the German prospective trials HIT 88/89 and HIT 91
-
Timmermann, B. et al. Combined postoperative irradiation and chemotherapy for anaplastic ependymomas in childhood: results of the German prospective trials HIT 88/89 and HIT 91. Int. J. Radiat. Oncol. Biol. Phys. 46, 287-295 (2000).
-
(2000)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.46
, pp. 287-295
-
-
Timmermann, B.1
-
162
-
-
20544467924
-
A multicenter retrospective study of chemotherapy for recurrent intracranial ependymal tumors in adults by the Gruppo Italiano Cooperativo di Neuro-Oncologia
-
Brandes, A. A. et al. A multicenter retrospective study of chemotherapy for recurrent intracranial ependymal tumors in adults by the Gruppo Italiano Cooperativo di Neuro-Oncologia. Cancer 104, 143-148 (2005).
-
(2005)
Cancer
, vol.104
, pp. 143-148
-
-
Brandes, A.A.1
-
163
-
-
85017214974
-
Dose-dense temozolomide + lapatinib for recurrent ependymoma
-
M. D. Anderson Cancer Center [online]
-
M. D. Anderson Cancer Center. Dose-dense temozolomide + lapatinib for recurrent ependymoma. ClinicalTrials.gov [online], https://clinicaltrials.gov/ ct2/show/NCT00826241?term=NCT00826241& rank=1 (2009).
-
(2009)
ClinicalTrials.gov
-
-
-
164
-
-
85017216100
-
Everolimus for children with recurrent or progressive ependymoma
-
University of Texas Southwestern Medical Center [online]
-
University of Texas Southwestern Medical Center. Everolimus for children with recurrent or progressive ependymoma. ClinicalTrials.gov [online], https:// clinicaltrials.gov/ct2/show/NCT02155920?term= NCT02155920&rank=1 (2014).
-
(2014)
ClinicalTrials.gov
-
-
-
165
-
-
85017212873
-
Carboplatin and bevacizumab for recurrent ependymoma
-
M. D. Anderson Cancer Center [online]
-
M. D. Anderson Cancer Center. Carboplatin and bevacizumab for recurrent ependymoma. ClinicalTrials.gov [online], https://clinicaltrials.gov/ ct2/show/NCT01295944?term=NCT01295944& rank=1 (2011).
-
(2011)
ClinicalTrials.gov
-
-
-
166
-
-
85017225030
-
Carboplatin as a radiosensitizer in treating childhood ependymoma
-
Ann & Robert H Lurie Children's Hospital of Chicago [online]
-
Ann & Robert H Lurie Children's Hospital of Chicago. Carboplatin as a radiosensitizer in treating childhood ependymoma. ClinicalTrials.gov [online], https:// clinicaltrials.gov/ct2/show/NCT01088035?term= NCT01088035&rank=1 (2010).
-
(2010)
ClinicalTrials.gov
-
-
-
167
-
-
84906773010
-
Health-related quality of life or quantity of life: A difficult trade-off in primary brain tumors?
-
Dirven, L., Reijneveld, J. C. & Taphoorn, M. J. Health-related quality of life or quantity of life: a difficult trade-off in primary brain tumors? Semin. Oncol. 41, 541-552 (2014).
-
(2014)
Semin. Oncol.
, vol.41
, pp. 541-552
-
-
Dirven, L.1
Reijneveld, J.C.2
Taphoorn, M.J.3
-
168
-
-
84868024273
-
Neurocognitive functioning in adult WHO grade II gliomas: Impact of old and new treatment modalities
-
Klein, M. Neurocognitive functioning in adult WHO grade II gliomas: impact of old and new treatment modalities. Neuro Oncol. 14, iv17-iv24 (2012).
-
(2012)
Neuro Oncol.
, vol.14
, pp. iv17-iv24
-
-
Klein, M.1
-
169
-
-
28044460508
-
Health-related quality of life in patients with glioblastoma: A randomised controlled trial
-
Taphoorn, M. J. et al. Health-related quality of life in patients with glioblastoma: a randomised controlled trial. Lancet Oncol. 6, 937-944 (2005).
-
(2005)
Lancet Oncol.
, vol.6
, pp. 937-944
-
-
Taphoorn, M.J.1
-
170
-
-
78449297440
-
Computer-based assessment of cognitive functions in brain tumor patients
-
Fliessbach, K. et al. Computer-based assessment of cognitive functions in brain tumor patients. J. Neurooncol. 100, 427-437 (2010).
-
(2010)
J. Neurooncol.
, vol.100
, pp. 427-437
-
-
Fliessbach, K.1
-
171
-
-
68249131500
-
Cognitive and radiological effects of radiotherapy in patients with low-grade glioma: Long-term follow-up
-
Douw, L. et al. Cognitive and radiological effects of radiotherapy in patients with low-grade glioma: long-term follow-up. Lancet Neurol. 8, 810-818 (2009).
-
(2009)
Lancet Neurol.
, vol.8
, pp. 810-818
-
-
Douw, L.1
-
172
-
-
0027407786
-
The Functional Assessment of Cancer Therapy scale: Development and validation of the general measure
-
Cella, D. F. et al. The Functional Assessment of Cancer Therapy scale: development and validation of the general measure. J. Clin. Oncol. 11, 570-579 (1993).
-
(1993)
J. Clin. Oncol.
, vol.11
, pp. 570-579
-
-
Cella, D.F.1
-
174
-
-
34547574155
-
The prognostic value of health-related quality-of-life data in predicting survival in glioblastoma cancer patients: Results from an international randomised phase III EORTC Brain Tumour and Radiation Oncology Groups, and NCIC Clinical Trials Group study
-
Mauer, M. et al. The prognostic value of health-related quality-of-life data in predicting survival in glioblastoma cancer patients: results from an international randomised phase III EORTC Brain Tumour and Radiation Oncology Groups, and NCIC Clinical Trials Group study. Br. J. Cancer 97, 302-307 (2007).
-
(2007)
Br. J. Cancer
, vol.97
, pp. 302-307
-
-
Mauer, M.1
-
175
-
-
84868029117
-
Neuro-oncology and palliative care: A challenging interface
-
Lin, E., Rosenthal, M. A., Le, B. H. & Eastman, P. Neuro-oncology and palliative care: a challenging interface. Neuro Oncol. 14, iv3-iv7 (2012).
-
(2012)
Neuro Oncol.
, vol.14
, pp. iv3-iv7
-
-
Lin, E.1
Rosenthal, M.A.2
Le, B.H.3
Eastman, P.4
-
176
-
-
84902668801
-
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
-
Patel, A. P. et al. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science 344, 1396-1401 (2014).
-
(2014)
Science
, vol.344
, pp. 1396-1401
-
-
Patel, A.P.1
-
177
-
-
85027948565
-
International Society of Neuropathology - Haarlem consensus guidelines for nervous system tumor classification and grading
-
Louis, D. N. et al. International Society of Neuropathology - Haarlem consensus guidelines for nervous system tumor classification and grading. Brain Pathol. 24, 429-435 (2014).
-
(2014)
Brain Pathol.
, vol.24
, pp. 429-435
-
-
Louis, D.N.1
-
178
-
-
84905675587
-
Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma
-
Ozawa, T. et al. Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma. Cancer Cell 26, 288-300 (2014).
-
(2014)
Cancer Cell
, vol.26
, pp. 288-300
-
-
Ozawa, T.1
-
179
-
-
84874598318
-
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
-
Sottoriva, A. et al. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proc. Natl Acad. Sci. USA 110, 4009-4014 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 4009-4014
-
-
Sottoriva, A.1
-
180
-
-
85017247508
-
Phase III study of rindopepimut/ GM-CSF in patients with newly diagnosed glioblastoma (ACT IV)
-
Celldex Therapeutics [online]
-
Celldex Therapeutics. Phase III study of rindopepimut/ GM-CSF in patients with newly diagnosed glioblastoma (ACT IV). ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/results?term= NCT01480479&Search=Search (2011).
-
(2011)
ClinicalTrials.gov
-
-
-
181
-
-
85017282391
-
Study of a drug [DCVax®-L] to treat newly diagnosed GBM brain cancer
-
Northwest Biotherapeutics [online]
-
Northwest Biotherapeutics. Study of a drug [DCVax®-L] to treat newly diagnosed GBM brain cancer. ClinicalTrials.gov [online], https://clinicaltrials.gov/ ct2/show/NCT00045968?term=NCT00045968& rank=1 (2002).
-
(2002)
ClinicalTrials.gov
-
-
-
182
-
-
84975204817
-
A randomized double blind placebo-controlled phase 2 trial of dendritic cell (DC) vaccine ICT-107 following standard treatment in newly diagnosed patients with GBM
-
Wen, P. et al. A randomized double blind placebo-controlled phase 2 trial of dendritic cell (DC) vaccine ICT-107 following standard treatment in newly diagnosed patients with GBM. Neuro Oncol. Abstr. 16, v22 (2014).
-
(2014)
Neuro Oncol. Abstr.
, vol.16
, pp. v22
-
-
Wen, P.1
-
183
-
-
84860209098
-
Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy
-
Dutoit, V. et al. Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy. Brain 135, 1042-1054 (2012).
-
(2012)
Brain
, vol.135
, pp. 1042-1054
-
-
Dutoit, V.1
-
184
-
-
84885659334
-
The regulatory landscape for actively personalized cancer immunotherapies
-
Britten, C. M. et al. The regulatory landscape for actively personalized cancer immunotherapies. Nat. Biotech. 31, 880-882 (2013).
-
(2013)
Nat. Biotech.
, vol.31
, pp. 880-882
-
-
Britten, C.M.1
-
185
-
-
85017215230
-
GAPVAC Phase I trial in newly diagnosed glioblastoma patients
-
immatics Biotechnologies GmbH [online]
-
immatics Biotechnologies GmbH. GAPVAC Phase I trial in newly diagnosed glioblastoma patients. ClinicalTrials.gov [online], https://clinicaltrials.gov/ ct2/show/NCT02149225?term=NCT02149225& rank=1 (2014).
-
(2014)
ClinicalTrials.gov
-
-
-
186
-
-
84961288435
-
First-in-human dose study of the novel transforming growth factor-β receptor I kinase inhibitor LY2157299 monohydrate in patients with advanced cancer and glioma
-
Rodon, J. et al. First-in-human dose study of the novel transforming growth factor-β receptor I kinase inhibitor LY2157299 monohydrate in patients with advanced cancer and glioma. Clin. Cancer Res. 21, 553-560 (2015).
-
(2015)
Clin. Cancer Res.
, vol.21
, pp. 553-560
-
-
Rodon, J.1
-
187
-
-
84895900553
-
Phase I study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the oral inhibitor of indoleamine 2,3-dioxygenase (IDO1) INCB024360 in patients (pts) with advanced malignancies
-
Beatty, G. L. et al. Phase I study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the oral inhibitor of indoleamine 2,3-dioxygenase (IDO1) INCB024360 in patients (pts) with advanced malignancies. J. Clin. Oncol. Abstr. 31, 3025 (2013).
-
(2013)
J. Clin. Oncol. Abstr.
, vol.31
, pp. 3025
-
-
Beatty, G.L.1
-
188
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi, F. S. et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363, 711-723 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
-
189
-
-
84874605864
-
Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma
-
Ribas, A. et al. Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. J. Clin. Oncol. 31, 616-622 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 616-622
-
-
Ribas, A.1
-
190
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok, J. D. et al. Nivolumab plus ipilimumab in advanced melanoma. N. Engl. J. Med. 369, 122-133 (2013).
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
-
191
-
-
84925045090
-
Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients
-
Mitchell, D. A. et al. Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients. Nature 519, 366-369 (2015).
-
(2015)
Nature
, vol.519
, pp. 366-369
-
-
Mitchell, D.A.1
-
192
-
-
84894265821
-
Glioma virus therapies between bench and bedside
-
Kaufmann, J. K. & Chiocca, E. A. Glioma virus therapies between bench and bedside. Neuro Oncol. 16, 334-351 (2014).
-
(2014)
Neuro Oncol.
, vol.16
, pp. 334-351
-
-
Kaufmann, J.K.1
Chiocca, E.A.2
-
193
-
-
84924422346
-
Interim analysis of the EF-14 Trial: A prospective, multi-center trial of NovoTTF-100A together with temozolomide compared to temozolomide alone in patients with newly diagnosed GBM
-
Stupp, R. et al. Interim analysis of the EF-14 Trial: a prospective, multi-center trial of NovoTTF-100A together with temozolomide compared to temozolomide alone in patients with newly diagnosed GBM. Neuro Oncol. Abstr. 16, v167 (2014).
-
(2014)
Neuro Oncol. Abstr.
, vol.16
, pp. v167
-
-
Stupp, R.1
-
194
-
-
84860487114
-
Phase 2 trial design in neuro-oncology revisited: A report from the RANO group
-
Galanis, E. et al. Phase 2 trial design in neuro-oncology revisited: a report from the RANO group. Lancet Oncol. 13, e196-e204 (2012).
-
(2012)
Lancet Oncol.
, vol.13
, pp. e196-e204
-
-
Galanis, E.1
-
195
-
-
85032136408
-
A phase 1 study evaluating ABT-414 with temozolomide (TMZ) or concurrent radiotherapy (RT) and TMZ in glioblastoma (GBM)
-
Gan, H. K. et al. A phase 1 study evaluating ABT-414 with temozolomide (TMZ) or concurrent radiotherapy (RT) and TMZ in glioblastoma (GBM). Neuro Oncol. Abstr. 16, v83 (2014).
-
(2014)
Neuro Oncol. Abstr.
, vol.16
, pp. v83
-
-
Gan, H.K.1
|