메뉴 건너뛰기




Volumn 16, Issue 3, 2014, Pages 334-351

Glioma virus therapies between bench and bedside

Author keywords

gene therapy; glioblastoma; oncolysis

Indexed keywords

GENE THERAPY; GLIOBLASTOMA; ONCOLYSIS;

EID: 84894265821     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/not310     Document Type: Article
Times cited : (65)

References (158)
  • 3
    • 84889680011 scopus 로고    scopus 로고
    • Adult cerebellar glioblastoma: Understanding survival and prognostic factors using a population-based database from 1973 to 2009
    • Adams H, Chaichana KL, Avendaño J, et al. Adult cerebellar glioblastoma: understanding survival and prognostic factors using a population-based database from 1973 to 2009.World Neurosurg. 2013;80:e237-e243.
    • (2013) World Neurosurg , vol.80
    • Adams, H.1    Chaichana, K.L.2    Avendaño, J.3
  • 4
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987-996.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    Van Den Bent, M.J.3
  • 5
    • 84879831552 scopus 로고    scopus 로고
    • Tailored therapy in diffuse gliomas: Using molecular classifiers to optimize clinical management
    • Taylor JW, Chi AS, Cahill DP. Tailored therapy in diffuse gliomas: using molecular classifiers to optimize clinical management. Oncol Williston Park N. 2013;27:504-514.
    • (2013) Oncol Williston Park N. , vol.27 , pp. 504-514
    • Taylor, J.W.1    Chi, A.S.2    Cahill, D.P.3
  • 6
    • 77955653868 scopus 로고    scopus 로고
    • Advanced MRI and PET imaging for assessment of treatment response in patients with gliomas
    • Dhermain FG, Hau P, Lanfermann H, et al. Advanced MRI and PET imaging for assessment of treatment response in patients with gliomas. Lancet Neurol. 2010;9:906-920.
    • (2010) Lancet Neurol , vol.9 , pp. 906-920
    • Dhermain, F.G.1    Hau, P.2    Lanfermann, H.3
  • 7
    • 84908233470 scopus 로고    scopus 로고
    • Intraoperative fluorescenceguided resection of high-grade gliomas: A comparison of the present techniques and evolution of future strategies
    • doi:10.1016/j.wneu.2013.06.014
    • Li Y, Rey-Dios R, Roberts DW, et al. Intraoperative fluorescenceguided resection of high-grade gliomas: a comparison of the present techniques and evolution of future strategies. World Neurosurg. 2013; doi:10.1016/j.wneu.2013. 06.014.
    • (2013) World Neurosurg
    • Li, Y.1    Rey-Dios, R.2    Roberts, D.W.3
  • 8
    • 84858609055 scopus 로고    scopus 로고
    • The role of BCNU polymer wafers (Gliadel) in the treatment of malignant glioma
    • Nagpal S. The role of BCNU polymer wafers (Gliadel) in the treatment of malignant glioma. Neurosurg Clin N Am. 2012;23: 289-295, ix.
    • (2012) Neurosurg Clin N Am , vol.23 , Issue.289-295
    • Nagpal, S.1
  • 9
    • 0015218266 scopus 로고
    • Regression of Burkitt's lymphoma in association with measles infection
    • Bluming AZ, Ziegler JL. Regression of Burkitt's lymphoma in association with measles infection. Lancet. 1971;2:105-106.
    • (1971) Lancet , vol.2 , pp. 105-106
    • Bluming, A.Z.1    Ziegler, J.L.2
  • 10
    • 33947245441 scopus 로고    scopus 로고
    • History of oncolytic viruses: Genesis to genetic engineering
    • Kelly E, Russell SJ. History of oncolytic viruses: genesis to genetic engineering. Mol Ther J Am Soc Gene Ther. 2007;15:651-659.
    • (2007) Mol Ther J Am Soc Gene Ther , vol.15 , pp. 651-659
    • Kelly, E.1    Russell, S.J.2
  • 11
    • 58849107795 scopus 로고    scopus 로고
    • Clinical testing of engineered oncolytic measles virus strains in the treatment of cancer: An overview
    • Msaouel P, Dispenzieri A, Galanis E. Clinical testing of engineered oncolytic measles virus strains in the treatment of cancer: an overview. Curr Opin Mol Ther. 2009;11:43-53.
    • (2009) Curr Opin Mol Ther , vol.11 , pp. 43-53
    • Msaouel, P.1    Dispenzieri, A.2    Galanis, E.3
  • 12
    • 84872683809 scopus 로고    scopus 로고
    • The art of gene therapy for glioma: A review of the challenging road to the bedside
    • Tobias A, Ahmed A, Moon K-S, et al. The art of gene therapy for glioma: a review of the challenging road to the bedside. J Neurol Neurosurg Psychiatry. 2013;84:213-222.
    • (2013) J Neurol Neurosurg Psychiatry. , vol.84 , pp. 213-222
    • Tobias, A.1    Ahmed, A.2    Moon, K.-S.3
  • 14
    • 84869073204 scopus 로고    scopus 로고
    • The gene therapy journey for hemophilia: Are we there yet?
    • High KA. The gene therapy journey for hemophilia: are we there yet? Blood. 2012;120:4482-4487.
    • (2012) Blood , vol.120 , pp. 4482-4487
    • High, K.A.1
  • 15
    • 84877852228 scopus 로고    scopus 로고
    • First gene therapy approved
    • Moran N. First gene therapy approved. Nat Biotechnol. 2012;30: 1153.
    • (2012) Nat Biotechnol , vol.30 , pp. 1153
    • Moran, N.1
  • 16
    • 0031949646 scopus 로고    scopus 로고
    • Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene
    • Yang L, Hwang R, Chiang Y, et al. Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene. Clin Cancer Res. 1998;4:731-741.
    • (1998) Clin Cancer Res , vol.4 , pp. 731-741
    • Yang, L.1    Hwang, R.2    Chiang, Y.3
  • 17
    • 0028864786 scopus 로고
    • The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro
    • Fick J, Barker FG 2nd, Dazin P, et al. The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro. Proc Natl Acad Sci USA. 1995;92:11071-11075.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11071-11075
    • Fick, J.1    Barker, I.I.F.G.2    Dazin, P.3
  • 18
    • 0034694011 scopus 로고    scopus 로고
    • A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
    • Rainov NG. A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum Gene Ther. 2000;11:2389-2401.
    • (2000) Hum Gene Ther , vol.11 , pp. 2389-2401
    • Rainov, N.G.1
  • 19
    • 2442767029 scopus 로고    scopus 로고
    • A phase I/II study of herpes simplex virus type 1 thymidine kinase suicide gene therapy for recurrent glioblastoma
    • Study Group on Gene Therapy for Glioblastoma
    • Klatzmann D, Valé ry CA, Bensimon G, et al. A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma. Hum Gene Ther. 1998;9:2595-2604.
    • (1998) Hum Gene Ther , vol.9 , pp. 2595-2604
    • Klatzmann, D.1    Valéry, C.A.2    Bensimon, G.3
  • 20
    • 0033588816 scopus 로고    scopus 로고
    • A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir
    • GLI328 European-Canadian Study Group
    • Shand N, Weber F, Mariani L, et al. A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group. Hum Gene Ther. 1999;10:2325-2335.
    • (1999) Hum Gene Ther , vol.10 , pp. 2325-2335
    • Shand, N.1    Weber, F.2    Mariani, L.3
  • 21
    • 0031463632 scopus 로고    scopus 로고
    • Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
    • Ram Z, Culver KW, Oshiro EM, et al. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nat Med. 1997;3:1354-1361.
    • (1997) Nat Med , vol.3 , pp. 1354-1361
    • Ram, Z.1    Culver, K.W.2    Oshiro, E.M.3
  • 22
    • 0033000339 scopus 로고    scopus 로고
    • Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: A pilot study in humans
    • Palù G, Cavaggioni A, Calvi P, et al. Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans. Gene Ther. 1999;6(3):330-337.
    • (1999) Gene Ther , vol.6 , Issue.3 , pp. 330-337
    • Palù, G.1    Cavaggioni, A.2    Calvi, P.3
  • 23
    • 0034329438 scopus 로고    scopus 로고
    • Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses
    • Sandmair AM, Loimas S, Puranen P, et al. Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses. Hum Gene Ther. 2000;11:2197-2205.
    • (2000) Hum Gene Ther , vol.11 , pp. 2197-2205
    • Sandmair, A.M.1    Loimas, S.2    Puranen, P.3
  • 24
    • 17344371681 scopus 로고    scopus 로고
    • Betagalactosidase gene transfer to human malignant glioma in vivo using replication-deficient retroviruses and adenoviruses
    • Puumalainen AM, Vapalahti M, Agrawal RS, et al. Betagalactosidase gene transfer to human malignant glioma in vivo using replication-deficient retroviruses and adenoviruses. Hum Gene Ther. 1998;9:1769-1774.
    • (1998) Hum Gene Ther , vol.9 , pp. 1769-1774
    • Puumalainen, A.M.1    Vapalahti, M.2    Agrawal, R.S.3
  • 25
    • 7044235842 scopus 로고    scopus 로고
    • AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: A randomised, controlled study
    • Immonen A, Vapalahti M, Tyynelä K, et al. AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study. Mol Ther. 2004;10: 967-972.
    • (2004) Mol Ther , vol.10 , pp. 967-972
    • Immonen, A.1    Vapalahti, M.2    Tyynelä, K.3
  • 26
    • 80053061789 scopus 로고    scopus 로고
    • Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma
    • Chiocca EA, Aguilar LK, Bell SD, et al. Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma. J Clin Oncol. 2011;29:3611-3619.
    • (2011) J Clin Oncol. , vol.29 , pp. 3611-3619
    • Chiocca, E.A.1    Aguilar, L.K.2    Bell, S.D.3
  • 27
    • 0035106088 scopus 로고    scopus 로고
    • Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis
    • Agard C, Ligeza C, Dupas B, et al. Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis. Cancer Gene Ther. 2001;8:128-136.
    • (2001) Cancer Gene Ther , vol.8 , pp. 128-136
    • Agard, C.1    Ligeza, C.2    Dupas, B.3
  • 28
    • 79960379942 scopus 로고    scopus 로고
    • Cytotoxic immunotherapy strategies for cancer: Mechanisms and clinical development
    • Aguilar LK, Guzik BW, Aguilar-Cordova E. Cytotoxic immunotherapy strategies for cancer: mechanisms and clinical development. J Cell Biochem. 2011;112:1969-1977.
    • (2011) J Cell Biochem , vol.112 , pp. 1969-1977
    • Aguilar, L.K.1    Guzik, B.W.2    Aguilar-Cordova, E.3
  • 29
    • 0032848688 scopus 로고    scopus 로고
    • Cancer gene therapy with HSV-tk/GCV system depends on T-cell-mediated immune responses and causes apoptotic death of tumor cells in vivo
    • Kuriyama S, Kikukawa M, Masui K, et al. Cancer gene therapy with HSV-tk/GCV system depends on T-cell-mediated immune responses and causes apoptotic death of tumor cells in vivo. Int J Cancer. 1999;83:374-380.
    • (1999) Int J Cancer , vol.83 , pp. 374-380
    • Kuriyama, S.1    Kikukawa, M.2    Masui, K.3
  • 30
    • 0035199415 scopus 로고    scopus 로고
    • Prostate-specific antigen response and systemic T cell activation after in situ gene therapy in prostate cancer patients failing radiotherapy
    • Miles BJ, Shalev M, Aguilar-Cordova E, et al. Prostate-specific antigen response and systemic T cell activation after in situ gene therapy in prostate cancer patients failing radiotherapy. Hum Gene Ther. 2001;12:1955-1967.
    • (2001) Hum Gene Ther , vol.12 , pp. 1955-1967
    • Miles, B.J.1    Shalev, M.2    Aguilar-Cordova, E.3
  • 31
    • 0028075655 scopus 로고
    • Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component
    • Vile RG, Nelson JA, Castleden S, et al. Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component. Cancer Res. 1994;54: 6228-6234.
    • (1994) Cancer Res , vol.54 , pp. 6228-6234
    • Vile, R.G.1    Nelson, J.A.2    Castleden, S.3
  • 32
    • 0034991065 scopus 로고    scopus 로고
    • Enhanced therapeutic effect of HSV-tk+GCV gene therapy and ionizing radiation for prostate cancer
    • Chhikara M, Huang H, Vlachaki MT, et al. Enhanced therapeutic effect of HSV-tk+GCV gene therapy and ionizing radiation for prostate cancer. Mol Ther. 2001;3:536-542.
    • (2001) Mol Ther , vol.3 , pp. 536-542
    • Chhikara, M.1    Huang, H.2    Vlachaki, M.T.3
  • 33
    • 33646009996 scopus 로고    scopus 로고
    • Sustained long-term immune responses after in situ gene therapy combined with radiotherapy and hormonal therapy in prostate cancer patients
    • Fujita T, Teh BS, Timme TL, et al. Sustained long-term immune responses after in situ gene therapy combined with radiotherapy and hormonal therapy in prostate cancer patients. Int J Radiat Oncol Biol Phys. 2006;65:84-90.
    • (2006) Int J Radiat Oncol Biol Phys , vol.65 , pp. 84-90
    • Fujita, T.1    Teh, B.S.2    Timme, T.L.3
  • 34
    • 39849092406 scopus 로고    scopus 로고
    • A phase i trial of Ad.hIFN-beta gene therapy for glioma
    • Chiocca EA, Smith KM, McKinney B, et al. A phase I trial of Ad.hIFN-beta gene therapy for glioma. Mol Ther. 2008;16: 618-626.
    • (2008) Mol Ther , vol.16 , pp. 618-626
    • Chiocca, E.A.1    Smith, K.M.2    McKinney, B.3
  • 35
    • 0025945333 scopus 로고
    • Intravenous recombinant interferon beta in patients with recurrent malignant gliomas: A phase I/II study
    • Yung WK, Prados M, Levin VA, et al. Intravenous recombinant interferon beta in patients with recurrent malignant gliomas: a phase I/II study. J Clin Oncol. 1991;9:1945-1949.
    • (1991) J Clin Oncol , vol.9 , pp. 1945-1949
    • Yung, W.K.1    Prados, M.2    Levin, V.A.3
  • 36
    • 30644457691 scopus 로고    scopus 로고
    • Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: Biological and clinical results
    • Colombo F, Barzon L, Franchin E, et al. Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: biological and clinical results. Cancer Gene Ther. 2005;12:835-848.
    • (2005) Cancer Gene Ther , vol.12 , pp. 835-848
    • Colombo, F.1    Barzon, L.2    Franchin, E.3
  • 37
    • 22944441622 scopus 로고    scopus 로고
    • Recombinant interleukin-2 enhanced the antitumor effect of ADV/RSV-HSV-tk/ACV therapy in a murine bladder cancer model
    • Terao S, Shirakawa T, Goda K, et al. Recombinant interleukin-2 enhanced the antitumor effect of ADV/RSV-HSV-tk/ACV therapy in a murine bladder cancer model. Anticancer Res. 2005;25: 2757-2760.
    • (2005) Anticancer Res , vol.25 , pp. 2757-2760
    • Terao, S.1    Shirakawa, T.2    Goda, K.3
  • 38
    • 78650000243 scopus 로고    scopus 로고
    • Prevention of intrahepatic metastasis of liver cancer by suicide gene therapy and chemokine ligand 2/monocyte chemoattractant protein-1 delivery in mice
    • Kakinoki K, Nakamoto Y, Kagaya T, et al. Prevention of intrahepatic metastasis of liver cancer by suicide gene therapy and chemokine ligand 2/monocyte chemoattractant protein-1 delivery in mice. J Gene Med. 2010;12:1002-1013.
    • (2010) J Gene Med , vol.12 , pp. 1002-1013
    • Kakinoki, K.1    Nakamoto, Y.2    Kagaya, T.3
  • 39
    • 70349941137 scopus 로고    scopus 로고
    • Antiglioma immunological memory in response to conditional cytotoxic/immune-stimulatory gene therapy: Humoral and cellular immunity lead to tumor regression
    • Ghulam Muhammad AKM, Candolfi M, King GD, et al. Antiglioma immunological memory in response to conditional cytotoxic/immune-stimulatory gene therapy: humoral and cellular immunity lead to tumor regression. Clin Cancer Res. 2009;15: 6113-6127.
    • (2009) Clin Cancer Res , vol.15 , pp. 6113-6127
    • Ghulam Muhammad, A.K.M.1    Candolfi, M.2    King, G.D.3
  • 40
    • 85027929861 scopus 로고    scopus 로고
    • Combined Flt3L/TK gene therapy induces immunological surveillance which mediates an immune response against a surrogate brain tumor neoantigen
    • King GD, Muhammad AKMG, Larocque D, et al. Combined Flt3L/TK gene therapy induces immunological surveillance which mediates an immune response against a surrogate brain tumor neoantigen. Mol Ther. 2011;19:1793-1801.
    • (2011) Mol Ther. , vol.19 , pp. 1793-1801
    • King, G.D.1    Muhammad, A.K.M.G.2    Larocque, D.3
  • 41
    • 84875634078 scopus 로고    scopus 로고
    • Safety profile, efficacy, and biodistribution of a bicistronic high-capacity adenovirus vector encoding a combined immunostimulation and cytotoxic gene therapy as a prelude to a phase i clinical trial for glioblastoma
    • Puntel M, Akm GM, Farrokhi C, et al. Safety profile, efficacy, and biodistribution of a bicistronic high-capacity adenovirus vector encoding a combined immunostimulation and cytotoxic gene therapy as a prelude to a phase I clinical trial for glioblastoma. Toxicol Appl Pharmacol. 2013;268:318-330.
    • (2013) Toxicol Appl Pharmacol. , vol.268 , pp. 318-330
    • Puntel, M.1    Akm, G.M.2    Farrokhi, C.3
  • 42
    • 33747273605 scopus 로고    scopus 로고
    • A pilot study of dose-intensified procarbazine, CCNU, vincristine for poor prognosis brain tumors utilizing fibronectin-assisted, retroviralmediated modification of CD34+ peripheral blood cells with O6-methylguanine DNA methyltransferase
    • Cornetta K, Croop J, Dropcho E, et al. A pilot study of dose-intensified procarbazine, CCNU, vincristine for poor prognosis brain tumors utilizing fibronectin-assisted, retroviralmediated modification of CD34+ peripheral blood cells with O6-methylguanine DNA methyltransferase. Cancer Gene Ther. 2006;13:886-895.
    • (2006) Cancer Gene Ther , vol.13 , pp. 886-895
    • Cornetta, K.1    Croop, J.2    Dropcho, E.3
  • 43
    • 0032813030 scopus 로고    scopus 로고
    • Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment
    • Maze R, Kurpad C, Pegg AE, et al. Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment. J Pharmacol Exp Ther. 1999;290:1467-1474.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 1467-1474
    • Maze, R.1    Kurpad, C.2    Pegg, A.E.3
  • 44
    • 1942469956 scopus 로고    scopus 로고
    • MGMT: Its role in cancer aetiology and cancer therapeutics
    • Gerson SL. MGMT: its role in cancer aetiology and cancer therapeutics. Nat Rev Cancer. 2004;4:296-307.
    • (2004) Nat Rev Cancer , vol.4 , pp. 296-307
    • Gerson, S.L.1
  • 45
    • 10744232285 scopus 로고    scopus 로고
    • In vivo selection of human hematopoietic cells in a xenograft model using combined pharmacologic and genetic manipulations
    • Pollok KE, Hartwell JR, Braber A, et al. In vivo selection of human hematopoietic cells in a xenograft model using combined pharmacologic and genetic manipulations. Hum Gene Ther. 2003; 14:1703-1714.
    • (2003) Hum Gene Ther , vol.14 , pp. 1703-1714
    • Pollok, K.E.1    Hartwell, J.R.2    Braber, A.3
  • 46
    • 33644852717 scopus 로고    scopus 로고
    • China approves world's first oncolytic virus therapy for cancer treatment
    • Garber K. China approves world's first oncolytic virus therapy for cancer treatment. J Natl Cancer Inst. 2006;98:298-300.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 298-300
    • Garber, K.1
  • 48
    • 84886101402 scopus 로고    scopus 로고
    • Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model
    • Huang TT, Hlavaty J, Ostertag D, et al. Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model. Cancer Gene Ther. 2013;20:544-551.
    • (2013) Cancer Gene Ther. , vol.20 , pp. 544-551
    • Huang, T.T.1    Hlavaty, J.2    Ostertag, D.3
  • 49
    • 0028108469 scopus 로고
    • Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
    • Huber BE, Austin EA, Richards CA, et al. Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Proc Natl Acad Sci USA. 1994;91: 8302-8306.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8302-8306
    • Huber, B.E.1    Austin, E.A.2    Richards, C.A.3
  • 50
    • 84867077136 scopus 로고    scopus 로고
    • Design and selection of Toca 511 for clinical use: Modified retroviral replicating vector with improved stability and gene expression
    • Perez OD, Logg CR, Hiraoka K, et al. Design and selection of Toca 511 for clinical use: modified retroviral replicating vector with improved stability and gene expression. Mol Ther. 2012;20:1689-1698.
    • (2012) Mol Ther , vol.20 , pp. 1689-1698
    • Perez, O.D.1    Logg, C.R.2    Hiraoka, K.3
  • 51
    • 0029665612 scopus 로고    scopus 로고
    • Selective in vitro replication of herpes simplex virus type 1 (HSV-1) ICP34.5 null mutants in primary human CNS tumours-evaluation of a potentially effective clinical therapy
    • McKie EA, MacLean AR, Lewis AD, et al. Selective in vitro replication of herpes simplex virus type 1 (HSV-1) ICP34.5 null mutants in primary human CNS tumours-evaluation of a potentially effective clinical therapy. Br J Cancer. 1996;74:745-752.
    • (1996) Br J Cancer , vol.74 , pp. 745-752
    • McKie, E.A.1    MacLean, A.R.2    Lewis, A.D.3
  • 52
    • 12944272092 scopus 로고    scopus 로고
    • Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma
    • Rampling R, Cruickshank G, Papanastassiou V, et al. Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma. Gene Ther. 2000;7:859-866.
    • (2000) Gene Ther , vol.7 , pp. 859-866
    • Rampling, R.1    Cruickshank, G.2    Papanastassiou, V.3
  • 53
    • 85047699172 scopus 로고    scopus 로고
    • The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: A proof of principle study
    • Papanastassiou V, Rampling R, Fraser M, et al. The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study. Gene Ther. 2002;9: 398-406.
    • (2002) Gene Ther , vol.9 , pp. 398-406
    • Papanastassiou, V.1    Rampling, R.2    Fraser, M.3
  • 54
    • 8844274068 scopus 로고    scopus 로고
    • HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: Safety data and long-term survival
    • Harrow S, Papanastassiou V, Harland J, et al. HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: safety data and long-term survival. Gene Ther. 2004;11:1648-1658.
    • (2004) Gene Ther , vol.11 , pp. 1648-1658
    • Harrow, S.1    Papanastassiou, V.2    Harland, J.3
  • 55
    • 0029023868 scopus 로고
    • Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
    • Mineta T, Rabkin SD, Yazaki T, et al. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat Med. 1995;1:938-943.
    • (1995) Nat Med , vol.1 , pp. 938-943
    • Mineta, T.1    Rabkin, S.D.2    Yazaki, T.3
  • 56
    • 47049091164 scopus 로고    scopus 로고
    • Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16
    • Aghi M, Visted T, Depinho RA, et al. Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16. Oncogene. 2008;27: 4249-4254.
    • (2008) Oncogene , vol.27 , pp. 4249-4254
    • Aghi, M.1    Visted, T.2    Depinho, R.A.3
  • 57
    • 12944315014 scopus 로고    scopus 로고
    • Conditionally replicating herpes simplex virus mutant G207 for the treatment of malignant glioma: Results of a phase i trial
    • Markert JM, Medlock MD, Rabkin SD, et al. Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial. Gene Ther. 2000;7:867-874.
    • (2000) Gene Ther , vol.7 , pp. 867-874
    • Markert, J.M.1    Medlock, M.D.2    Rabkin, S.D.3
  • 58
    • 58149237728 scopus 로고    scopus 로고
    • Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM
    • Markert JM, Liechty PG, Wang W, et al. Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM. Mol Ther. 2009;17:199-207.
    • (2009) Mol Ther , vol.17 , pp. 199-207
    • Markert, J.M.1    Liechty, P.G.2    Wang, W.3
  • 59
    • 0035933088 scopus 로고    scopus 로고
    • Oncolytic herpes simplex virus vector with enhanced MHC class i presentation and tumor cell killing
    • Todo T, Martuza RL, Rabkin SD, et al. Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing. Proc Natl Acad Sci USA. 2001;98:6396-6401.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6396-6401
    • Todo, T.1    Martuza, R.L.2    Rabkin, S.D.3
  • 60
    • 7044228126 scopus 로고    scopus 로고
    • A phase i open-label, dose-escalation, multi-institutional trial of injection with an E1B-attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting
    • Chiocca EA, Abbed KM, Tatter S, et al. A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. Mol Ther. 2004;10:958-966.
    • (2004) Mol Ther , vol.10 , pp. 958-966
    • Chiocca, E.A.1    Abbed, K.M.2    Tatter, S.3
  • 61
    • 19944363519 scopus 로고    scopus 로고
    • Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity
    • O'Shea CC, Johnson L, Bagus B, et al. Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity. Cancer Cell. 2004;6:611-623.
    • (2004) Cancer Cell , vol.6 , pp. 611-623
    • O'Shea, C.C.1    Johnson, L.2    Bagus, B.3
  • 62
    • 22244479672 scopus 로고    scopus 로고
    • Heat shock phenocopies E1B-55 K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic viral therapy
    • O'Shea CC, Soria C, Bagus B, et al. Heat shock phenocopies E1B-55 K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic viral therapy. Cancer Cell. 2005;8:61-74.
    • (2005) Cancer Cell , vol.8 , pp. 61-74
    • O'Shea, C.C.1    Soria, C.2    Bagus, B.3
  • 63
    • 84855866162 scopus 로고    scopus 로고
    • Response to intra-arterial oncolytic virotherapy with the herpes virus NV1020 evaluated by [18F]fluorodeoxyglucose positron emission tomography and computed tomography
    • Sze DY, Iagaru AH, Gambhir SS, et al. Response to intra-arterial oncolytic virotherapy with the herpes virus NV1020 evaluated by [18F]fluorodeoxyglucose positron emission tomography and computed tomography. Hum Gene Ther. 2012;23:91-97.
    • (2012) Hum Gene Ther , vol.23 , pp. 91-97
    • Sze, D.Y.1    Iagaru, A.H.2    Gambhir, S.S.3
  • 64
    • 28844468988 scopus 로고    scopus 로고
    • Phase I/II trial of intravenous NDV-HUJ oncolytic virus in recurrent glioblastoma multiforme
    • Freeman AI, Zakay-Rones Z, Gomori JM, et al. Phase I/II trial of intravenous NDV-HUJ oncolytic virus in recurrent glioblastoma multiforme. Mol Ther. 2006;13:221-228.
    • (2006) Mol Ther , vol.13 , pp. 221-228
    • Freeman, A.I.1    Zakay-Rones, Z.2    Gomori, J.M.3
  • 65
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
    • Wolchok JD, Hoos A, O'Day S, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res. 2009;15:7412-7420.
    • (2009) Clin Cancer Res , vol.15 , pp. 7412-7420
    • Wolchok, J.D.1    Hoos, A.2    O'Day, S.3
  • 66
    • 84856114191 scopus 로고    scopus 로고
    • Application of novel response/progression measures for surgically delivered therapies for gliomas: Response Assessment in Neuro-Oncology (RANO) working group
    • VogelbaumMA, Jost S, Aghi MK, et al. Application of novel response/progression measures for surgically delivered therapies for gliomas: Response Assessment in Neuro-Oncology (RANO) working group. Neurosurgery. 2012;70:234-243.
    • (2012) Neurosurgery , vol.70 , pp. 234-243
    • Vogelbaum, M.A.1    Jost, S.2    Aghi, M.K.3
  • 67
    • 84884248472 scopus 로고    scopus 로고
    • Early pseudoprogression following chemoradiotherapy in glioblastoma patients: The value of RANO evaluation
    • Article ID 690585
    • Linhares P, Carvalho B, Figueiredo R, et al. Early pseudoprogression following chemoradiotherapy in glioblastoma patients: the value of RANO evaluation. J Oncol. 2013;2013:Article ID 690585.
    • (2013) J Oncol. 2013
    • Linhares, P.1    Carvalho, B.2    Figueiredo, R.3
  • 68
    • 0038288854 scopus 로고    scopus 로고
    • Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway
    • Fueyo J, Alemany R, Gomez-Manzano C, et al. Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway. J Natl Cancer Inst. 2003;95:652-660.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 652-660
    • Fueyo, J.1    Alemany, R.2    Gomez-Manzano, C.3
  • 69
    • 84885001986 scopus 로고    scopus 로고
    • Panorama from the oncolytic virotherapy summit
    • Pol JG, Marguerie M, Arulanandam R, et al. Panorama from the Oncolytic Virotherapy Summit. Mol Ther. 2013;21:1814-1818.
    • (2013) Mol Ther. , vol.21 , pp. 1814-1818
    • Pol, J.G.1    Marguerie, M.2    Arulanandam, R.3
  • 70
    • 77953508940 scopus 로고    scopus 로고
    • Preparing an oncolytic poliovirus recombinant for clinical application against glioblastoma multiforme
    • Goetz C, Gromeier M. Preparing an oncolytic poliovirus recombinant for clinical application against glioblastoma multiforme. Cytokine Growth Factor Rev. 2010;21:197-203.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 197-203
    • Goetz, C.1    Gromeier, M.2
  • 71
    • 0032515141 scopus 로고    scopus 로고
    • Reovirus therapy of tumors with activated Ras pathway
    • Coffey MC, Strong JE, Forsyth PA, et al. Reovirus therapy of tumors with activated Ras pathway. Science. 1998;282:1332-1334.
    • (1998) Science , vol.282 , pp. 1332-1334
    • Coffey, M.C.1    Strong, J.E.2    Forsyth, P.A.3
  • 72
    • 39849099798 scopus 로고    scopus 로고
    • A phase i trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas
    • Forsyth P, Roldán G, George D, et al. A phase I trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas. Mol Ther. 2008;16:627-632.
    • (2008) Mol Ther , vol.16 , pp. 627-632
    • Forsyth, P.1    Roldán, G.2    George, D.3
  • 73
    • 0742287881 scopus 로고    scopus 로고
    • Parvovirus H-1 infection of human glioma cells leads to complete viral replication and efficient cell killing
    • Herrero Y, Calle M, Cornelis JJ, et al. Parvovirus H-1 infection of human glioma cells leads to complete viral replication and efficient cell killing. Int J Cancer. 2004;109:76-84.
    • (2004) Int J Cancer , vol.109 , pp. 76-84
    • Herrero, Y.1    Calle, M.2    Cornelis, J.J.3
  • 74
    • 84858608281 scopus 로고    scopus 로고
    • Phase I/IIa study of intratumoral/intracerebral or intravenous/ intracerebral administration of parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol
    • Geletneky K, Huesing J, Rommelaere J, et al. Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol. BMC Cancer. 2012;12:99.
    • (2012) BMC Cancer , vol.12 , pp. 99
    • Geletneky, K.1    Huesing, J.2    Rommelaere, J.3
  • 75
    • 76249123546 scopus 로고    scopus 로고
    • Phase i trial of intraperitoneal administration of an oncolytic measles virus strain engineered to express carcinoembryonic antigen for recurrent ovarian cancer
    • Galanis E, Hartmann LC, Cliby WA, et al. Phase I trial of intraperitoneal administration of an oncolytic measles virus strain engineered to express carcinoembryonic antigen for recurrent ovarian cancer. Cancer Res. 2010;70:875-882.
    • (2010) Cancer Res , vol.70 , pp. 875-882
    • Galanis, E.1    Hartmann, L.C.2    Cliby, W.A.3
  • 76
    • 84865487983 scopus 로고    scopus 로고
    • Convection-enhanced delivery: From mechanisms to clinical drug delivery for diseases of the central nervous system
    • Saito R, Tominaga T. Convection-enhanced delivery: from mechanisms to clinical drug delivery for diseases of the central nervous system. Neurol Med Chir (Tokyo). 2012;52:531-538.
    • (2012) Neurol Med Chir (Tokyo) , vol.52 , pp. 531-538
    • Saito, R.1    Tominaga, T.2
  • 77
    • 70349932734 scopus 로고    scopus 로고
    • Reovirus: Rationale and clinical trial update
    • Lal R, Harris D, Postel-Vinay S, et al. Reovirus: rationale and clinical trial update. Curr Opin Mol Ther. 2009;11:532-539.
    • (2009) Curr Opin Mol Ther , vol.11 , pp. 532-539
    • Lal, R.1    Harris, D.2    Postel-Vinay, S.3
  • 78
    • 80052406557 scopus 로고    scopus 로고
    • Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans
    • Breitbach CJ, Burke J, Jonker D, et al. Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans. Nature. 2011;477:99-102.
    • (2011) Nature. , vol.477 , pp. 99-102
    • Breitbach, C.J.1    Burke, J.2    Jonker, D.3
  • 79
    • 0032814773 scopus 로고    scopus 로고
    • Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses
    • Ikeda K, Ichikawa T, Wakimoto H, et al. Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses. Nat Med. 1999;5:881-887.
    • (1999) Nat Med , vol.5 , pp. 881-887
    • Ikeda, K.1    Ichikawa, T.2    Wakimoto, H.3
  • 80
    • 0033997183 scopus 로고    scopus 로고
    • Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant
    • Ikeda K, Wakimoto H, Ichikawa T, et al. Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication- conditional herpes simplex virus mutant. J Virol. 2000;74:4765-4775.
    • (2000) J Virol , vol.74 , pp. 4765-4775
    • Ikeda, K.1    Wakimoto, H.2    Ichikawa, T.3
  • 81
    • 0036199737 scopus 로고    scopus 로고
    • The complement response against an oncolytic virus is species-specific in its activation pathways
    • Wakimoto H, Ikeda K, Abe T, et al. The complement response against an oncolytic virus is species-specific in its activation pathways. Mol Ther. 2002;5:275-282.
    • (2002) Mol Ther , vol.5 , pp. 275-282
    • Wakimoto, H.1    Ikeda, K.2    Abe, T.3
  • 82
    • 77956585904 scopus 로고    scopus 로고
    • Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficacy
    • Short JJ, Rivera AA,Wu H, et al. Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficacy. Mol Cancer Ther. 2010;9:2536-2544.
    • (2010) Mol Cancer Ther , vol.9 , pp. 2536-2544
    • Short, J.J.1    Rivera, A.A.2    Wu, H.3
  • 84
    • 67650675099 scopus 로고    scopus 로고
    • Pharmacologic and chemical adjuvants in tumor virotherapy
    • Alvarez-Breckenridge C, Kaur B, Chiocca EA. Pharmacologic and chemical adjuvants in tumor virotherapy. Chem Rev. 2009;109: 3125-3140.
    • (2009) Chem Rev , vol.109 , pp. 3125-3140
    • Alvarez-Breckenridge, C.1    Kaur, B.2    Chiocca, E.A.3
  • 85
    • 79952960255 scopus 로고    scopus 로고
    • Pharmacological interventions for improving adenovirus usage in gene therapy
    • Haisma HJ, Bellu AR. Pharmacological interventions for improving adenovirus usage in gene therapy. Mol Pharm. 2011;8:50-55.
    • (2011) Mol Pharm. , vol.8 , pp. 50-55
    • Haisma, H.J.1    Bellu, A.R.2
  • 86
    • 84863112893 scopus 로고    scopus 로고
    • Virus chimeras for gene therapy, vaccination, and oncolysis: Adenoviruses and beyond
    • Kaufmann JK, Nettelbeck DM. Virus chimeras for gene therapy, vaccination, and oncolysis: adenoviruses and beyond. Trends Mol Med. 2012;18:365-376.
    • (2012) Trends Mol Med , vol.18 , pp. 365-376
    • Kaufmann, J.K.1    Nettelbeck, D.M.2
  • 87
    • 84861195591 scopus 로고    scopus 로고
    • Pharmacokinetic study of neural stem cell-based cell carrier for oncolytic virotherapy: Targeted delivery of the therapeutic payload in an orthotopic brain tumor model
    • Thaci B, Ahmed AU, Ulasov IV, et al. Pharmacokinetic study of neural stem cell-based cell carrier for oncolytic virotherapy: targeted delivery of the therapeutic payload in an orthotopic brain tumor model. Cancer Gene Ther. 2012;19:431-442.
    • (2012) Cancer Gene Ther , vol.19 , pp. 431-442
    • Thaci, B.1    Ahmed, A.U.2    Ulasov, I.V.3
  • 88
    • 84872681869 scopus 로고    scopus 로고
    • Optimizing patient derived mesenchymal stem cells as virus carriers for a phase i clinical trial in ovarian cancer
    • Mader EK, Butler G, Dowdy SC, et al. Optimizing patient derived mesenchymal stem cells as virus carriers for a phase I clinical trial in ovarian cancer. J Transl Med. 2013;11:20.
    • (2013) J Transl Med. , vol.11 , pp. 20
    • Mader, E.K.1    Butler, G.2    Dowdy, S.C.3
  • 89
    • 84878335302 scopus 로고    scopus 로고
    • Neural stem cell-mediated enzyme/prodrug therapy for glioma: Preclinical studies
    • Aboody KS, Najbauer J, Metz MZ, et al. Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies. Sci Transl Med. 2013;5:184ra59.
    • (2013) Sci Transl Med. , vol.5
    • Aboody, K.S.1    Najbauer, J.2    Metz, M.Z.3
  • 90
    • 84883438714 scopus 로고    scopus 로고
    • The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma
    • Tobias AL, Thaci B, Auffinger B, et al. The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma. Stem Cells Transl Med. 2013;2:655-666.
    • (2013) Stem Cells Transl Med. , vol.2 , pp. 655-666
    • Tobias, A.L.1    Thaci, B.2    Auffinger, B.3
  • 91
    • 84857364081 scopus 로고    scopus 로고
    • Targeted entry of enveloped viruses: Measles and herpes simplex virus i
    • Navaratnarajah CK, Miest TS, Carfi A, et al. Targeted entry of enveloped viruses: measles and herpes simplex virus I. Curr Opin Virol. 2012;2:43-49.
    • (2012) Curr Opin Virol , vol.2 , pp. 43-49
    • Navaratnarajah, C.K.1    Miest, T.S.2    Carfi, A.3
  • 92
    • 0345687967 scopus 로고    scopus 로고
    • Retargeting of adenoviral infection to melanoma: Combining genetic ablation of native tropism with a recombinant bispecific single-chain diabody (scDb) adapter that binds to fiber knob and HMWMAA
    • Nettelbeck DM, Rivera AA, Kupsch J, et al. Retargeting of adenoviral infection to melanoma: combining genetic ablation of native tropism with a recombinant bispecific single-chain diabody (scDb) adapter that binds to fiber knob and HMWMAA. Int J Cancer. 2004; 108:136-145.
    • (2004) Int J Cancer , vol.108 , pp. 136-145
    • Nettelbeck, D.M.1    Rivera, A.A.2    Kupsch, J.3
  • 93
    • 0344188096 scopus 로고    scopus 로고
    • An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
    • Bischoff JR, Kirn DH, Williams A, et al. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science. 1996;274:373-376.
    • (1996) Science , vol.274 , pp. 373-376
    • Bischoff, J.R.1    Kirn, D.H.2    Williams, A.3
  • 94
    • 61649088631 scopus 로고    scopus 로고
    • MicroRNAs and the regulation of vector tropism
    • Kelly EJ, Russell SJ. MicroRNAs and the regulation of vector tropism. Mol Ther. 2009;17:409-416.
    • (2009) Mol Ther , vol.17 , pp. 409-416
    • Kelly, E.J.1    Russell, S.J.2
  • 95
    • 79957889064 scopus 로고    scopus 로고
    • MicroRNA-sensitive oncolytic measles viruses for cancer-specific vector tropism
    • Leber MF, Bossow S, Leonard VHJ, et al. MicroRNA-sensitive oncolytic measles viruses for cancer-specific vector tropism. Mol Ther. 2011;19:1097-1106.
    • (2011) Mol Ther. , vol.19 , pp. 1097-1106
    • Leber, M.F.1    Bossow, S.2    Leonard, V.H.J.3
  • 96
    • 84871984467 scopus 로고    scopus 로고
    • Attenuation of Semliki Forest virus neurovirulence by microRNA-mediated detargeting
    • Ylösmä ki E, Martikainen M, Hinkkanen A, et al. Attenuation of Semliki Forest virus neurovirulence by microRNA-mediated detargeting. J Virol. 2013;87:335-344.
    • (2013) J Virol , vol.87 , pp. 335-344
    • Ylösmä Ki, E.1    Martikainen, M.2    Hinkkanen, A.3
  • 98
    • 84883189850 scopus 로고    scopus 로고
    • MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells
    • Peruzzi P, Bronisz A, Nowicki MO, et al. MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells. Neuro-Oncol. 2013;15:1212-1224.
    • (2013) Neuro-Oncol. , vol.15 , pp. 1212-1224
    • Peruzzi, P.1    Bronisz, A.2    Nowicki, M.O.3
  • 99
    • 65749089629 scopus 로고    scopus 로고
    • Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis
    • Dorer DE, Nettelbeck DM. Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis. Adv Drug Deliv Rev. 2009; 61:554-571.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 554-571
    • Dorer, D.E.1    Nettelbeck, D.M.2
  • 100
    • 34548565837 scopus 로고    scopus 로고
    • Improved glioblastoma treatment with Ad5/35 fiber chimeric conditionally replicating adenoviruses
    • Hoffmann D, Meyer B, Wildner O. Improved glioblastoma treatment with Ad5/35 fiber chimeric conditionally replicating adenoviruses. J Gene Med. 2007;9:764-778.
    • (2007) J Gene Med , vol.9 , pp. 764-778
    • Hoffmann, D.1    Meyer, B.2    Wildner, O.3
  • 101
    • 29944447647 scopus 로고    scopus 로고
    • Enhanced therapeutic efficacy of G207 for the treatment of glioma through Musashi1 promoter retargeting of gamma34.5-mediated virulence
    • Kanai R, Tomita H, Shinoda A, et al. Enhanced therapeutic efficacy of G207 for the treatment of glioma through Musashi1 promoter retargeting of gamma34.5-mediated virulence. Gene Ther. 2006; 13:106-116.
    • (2006) Gene Ther , vol.13 , pp. 106-116
    • Kanai, R.1    Tomita, H.2    Shinoda, A.3
  • 102
    • 16844366956 scopus 로고    scopus 로고
    • An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor
    • Kambara H, Okano H, Chiocca EA, et al. An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor. Cancer Res. 2005;65:2832-2839.
    • (2005) Cancer Res , vol.65 , pp. 2832-2839
    • Kambara, H.1    Okano, H.2    Chiocca, E.A.3
  • 103
    • 84887116567 scopus 로고    scopus 로고
    • DNA demethylating agents synergize with oncolytic HSV1 against malignant gliomas
    • Okemoto K, Kasai K, Wagner B, et al. DNA demethylating agents synergize with oncolytic HSV1 against malignant gliomas. Clin Cancer Res. 2013;19:5952-5959.
    • (2013) Clin Cancer Res. , vol.19 , pp. 5952-5959
    • Okemoto, K.1    Kasai, K.2    Wagner, B.3
  • 104
    • 0842325802 scopus 로고    scopus 로고
    • Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population
    • Brat DJ, Castellano-Sanchez AA, Hunter SB, et al. Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population. Cancer Res. 2004;64:920-927.
    • (2004) Cancer Res , vol.64 , pp. 920-927
    • Brat, D.J.1    Castellano-Sanchez, A.A.2    Hunter, S.B.3
  • 105
    • 79251591038 scopus 로고    scopus 로고
    • Glioblastoma, cancer stem cells and hypoxia
    • Bar EE. Glioblastoma, cancer stem cells and hypoxia. Brain Pathol. 2011;21:119-129.
    • (2011) Brain Pathol. , vol.21 , pp. 119-129
    • Bar, E.E.1
  • 106
    • 0036399291 scopus 로고    scopus 로고
    • New oncolytic adenoviruses with hypoxia-and estrogen receptor-regulated replication
    • Hernandez-Alcoceba R, Pihalja M, Qian D, et al. New oncolytic adenoviruses with hypoxia-and estrogen receptor-regulated replication. Hum Gene Ther. 2002;13:1737-1750.
    • (2002) Hum Gene Ther , vol.13 , pp. 1737-1750
    • Hernandez-Alcoceba, R.1    Pihalja, M.2    Qian, D.3
  • 107
    • 11144229120 scopus 로고    scopus 로고
    • Cancer therapy with a replicating oncolytic adenovirus targeting the hypoxic microenvironment of tumors
    • Post DE, Devi NS, Li Z, et al. Cancer therapy with a replicating oncolytic adenovirus targeting the hypoxic microenvironment of tumors. Clin Cancer Res. 2004;10:8603-8612.
    • (2004) Clin Cancer Res , vol.10 , pp. 8603-8612
    • Post, D.E.1    Devi, N.S.2    Li, Z.3
  • 108
    • 78751631362 scopus 로고    scopus 로고
    • Development of an oncolytic herpes simplex virus using a tumor-specific HIF-responsive promoter
    • Longo SL, Griffith C, Glass A, et al. Development of an oncolytic herpes simplex virus using a tumor-specific HIF-responsive promoter. Cancer Gene Ther. 2011;18:123-134.
    • (2011) Cancer Gene Ther. , vol.18 , pp. 123-134
    • Longo, S.L.1    Griffith, C.2    Glass, A.3
  • 109
    • 0034880629 scopus 로고    scopus 로고
    • A hypoxia-regulated adeno-associated virus vector for cancer-specific gene therapy
    • Ruan H, Su H, Hu L, et al. A hypoxia-regulated adeno-associated virus vector for cancer-specific gene therapy. Neoplasia. 2001;3: 255-263.
    • (2001) Neoplasia , vol.3 , pp. 255-263
    • Ruan, H.1    Su, H.2    Hu, L.3
  • 110
    • 58149214278 scopus 로고    scopus 로고
    • Hypoxia enhances the replication of oncolytic herpes simplex virus
    • Aghi MK, Liu T-C, Rabkin S, et al. Hypoxia enhances the replication of oncolytic herpes simplex virus. Mol Ther. 2009;17:51-56.
    • (2009) Mol Ther , vol.17 , pp. 51-56
    • Aghi, M.K.1    Liu, T.-C.2    Rabkin, S.3
  • 111
    • 49249105564 scopus 로고    scopus 로고
    • Overcoming the extracellular matrix barrier to improve intratumoral spread and therapeutic potential of oncolytic virotherapy
    • Yun C-O. Overcoming the extracellular matrix barrier to improve intratumoral spread and therapeutic potential of oncolytic virotherapy. Curr Opin Mol Ther. 2008;10:356-361.
    • (2008) Curr Opin Mol Ther , vol.10 , pp. 356-361
    • Yun, C.-O.1
  • 112
    • 79952594233 scopus 로고    scopus 로고
    • Losartan inhibits collagen i synthesis and improves the distribution and efficacy of nanotherapeutics in tumors
    • Diop-Frimpong B, Chauhan VP, Krane S, et al. Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors. Proc Natl Acad Sci USA. 2011;108: 2909-2914.
    • (2011) Proc Natl Acad Sci USA. , vol.108 , pp. 2909-2914
    • Diop-Frimpong, B.1    Chauhan, V.P.2    Krane, S.3
  • 113
    • 77955403005 scopus 로고    scopus 로고
    • Hyaluronidase expression by an oncolytic adenovirus enhances its intratumoral spread and suppresses tumor growth
    • Guedan S, Rojas JJ, Gros A, et al. Hyaluronidase expression by an oncolytic adenovirus enhances its intratumoral spread and suppresses tumor growth. Mol Ther. 2010;18:1275-1283.
    • (2010) Mol Ther , vol.18 , pp. 1275-1283
    • Guedan, S.1    Rojas, J.J.2    Gros, A.3
  • 114
    • 79952719169 scopus 로고    scopus 로고
    • Chondroitinase ABC I-mediated enhancement of oncolytic virus spread and antitumor efficacy
    • Dmitrieva N, Yu L, Viapiano M, et al. Chondroitinase ABC I-mediated enhancement of oncolytic virus spread and antitumor efficacy. Clin Cancer Res. 2011;17:1362-1372.
    • (2011) Clin Cancer Res. , vol.17 , pp. 1362-1372
    • Dmitrieva, N.1    Yu, L.2    Viapiano, M.3
  • 115
    • 84890870665 scopus 로고    scopus 로고
    • Switching a replication-defective adenoviral vector into a replication-competent, oncolytic adenovirus
    • Nakashima H, Chiocca EA. Switching a replication-defective adenoviral vector into a replication-competent, oncolytic adenovirus. J Virol. 2014;88:345-353.
    • (2014) J Virol. , vol.88 , pp. 345-353
    • Nakashima, H.1    Chiocca, E.A.2
  • 116
    • 84874771300 scopus 로고    scopus 로고
    • Using clinically approved cyclophosphamide regimens to control the humoral immune response to oncolytic viruses
    • Peng K-W, Myers R, Greenslade A, et al. Using clinically approved cyclophosphamide regimens to control the humoral immune response to oncolytic viruses. Gene Ther. 2013;20: 255-261.
    • (2013) Gene Ther. , vol.20 , pp. 255-261
    • Peng, K.-W.1    Myers, R.2    Greenslade, A.3
  • 117
    • 33748088164 scopus 로고    scopus 로고
    • Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses
    • Fulci G, Breymann L, Gianni D, et al. Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses. Proc Natl Acad Sci USA. 2006;103:12873-12878.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12873-12878
    • Fulci, G.1    Breymann, L.2    Gianni, D.3
  • 118
    • 77950480974 scopus 로고    scopus 로고
    • Treatment of chronic lymphocytic leukemia with genetically targeted autologous T cells: Case report of an unforeseen adverse event in a phase i clinical trial
    • Brentjens R, Yeh R, Bernal Y, et al. Treatment of chronic lymphocytic leukemia with genetically targeted autologous T cells: case report of an unforeseen adverse event in a phase I clinical trial. Mol Ther. 2010;18:666-668.
    • (2010) Mol Ther , vol.18 , pp. 666-668
    • Brentjens, R.1    Yeh, R.2    Bernal, Y.3
  • 119
    • 84870909657 scopus 로고    scopus 로고
    • NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors
    • Alvarez-Breckenridge CA, Yu J, Price R, et al. NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors. Nat Med. 2012;18:1827-1834.
    • (2012) Nat Med , vol.18 , pp. 1827-1834
    • Alvarez-Breckenridge, C.A.1    Yu, J.2    Price, R.3
  • 120
    • 35148871720 scopus 로고    scopus 로고
    • Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses
    • Fulci G, Dmitrieva N, Gianni D, et al. Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Res. 2007;67:9398-9406.
    • (2007) Cancer Res , vol.67 , pp. 9398-9406
    • Fulci, G.1    Dmitrieva, N.2    Gianni, D.3
  • 121
    • 79952361112 scopus 로고    scopus 로고
    • Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-kB mediated and supports innate and adaptive anti-tumour immune priming
    • Steele L, Errington F, Prestwich R, et al. Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-kB mediated and supports innate and adaptive anti-tumour immune priming. Mol Cancer. 2011;10:20.
    • (2011) Mol Cancer. , vol.10 , pp. 20
    • Steele, L.1    Errington, F.2    Prestwich, R.3
  • 122
    • 67650375869 scopus 로고    scopus 로고
    • Immune-mediated antitumor activity of reovirus is required for therapy and is independent of direct viral oncolysis and replication
    • Prestwich RJ, Ilett EJ, Errington F, et al. Immune-mediated antitumor activity of reovirus is required for therapy and is independent of direct viral oncolysis and replication. Clin Cancer Res. 2009;15:4374-4381.
    • (2009) Clin Cancer Res , vol.15 , pp. 4374-4381
    • Prestwich, R.J.1    Ilett, E.J.2    Errington, F.3
  • 123
    • 76749162295 scopus 로고    scopus 로고
    • Single-cycle viral gene expression, rather than progressive replication and oncolysis, is required for VSV therapy of B16 melanoma
    • Galivo F, Diaz RM, Wongthida P, et al. Single-cycle viral gene expression, rather than progressive replication and oncolysis, is required for VSV therapy of B16 melanoma. Gene Ther. 2010;17: 158-170.
    • (2010) Gene Ther , vol.17 , pp. 158-170
    • Galivo, F.1    Diaz, R.M.2    Wongthida, P.3
  • 124
    • 84863717012 scopus 로고    scopus 로고
    • Activation of a glioma-specific immune response by oncolytic parvovirus Minute Virus of Mice infection
    • Grekova SP, Raykov Z, Zawatzky R, et al. Activation of a glioma-specific immune response by oncolytic parvovirus Minute Virus of Mice infection. Cancer Gene Ther. 2012;19:468-475.
    • (2012) Cancer Gene Ther , vol.19 , pp. 468-475
    • Grekova, S.P.1    Raykov, Z.2    Zawatzky, R.3
  • 125
    • 63649137545 scopus 로고    scopus 로고
    • Targeting the intratumoral dendritic cells by the oncolytic adenoviral vaccine expressing RANTES elicits potent antitumor immunity
    • Lapteva N, Aldrich M, Weksberg D, et al. Targeting the intratumoral dendritic cells by the oncolytic adenoviral vaccine expressing RANTES elicits potent antitumor immunity. J Immunother. 2009; 32:145-156.
    • (2009) J Immunother , vol.32 , pp. 145-156
    • Lapteva, N.1    Aldrich, M.2    Weksberg, D.3
  • 126
    • 0037295403 scopus 로고    scopus 로고
    • ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties
    • Liu BL, Robinson M, Han Z-Q, et al. ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties. Gene Ther. 2003;10:292-303.
    • (2003) Gene Ther , vol.10 , pp. 292-303
    • Liu, B.L.1    Robinson, M.2    Han, Z.-Q.3
  • 127
    • 33746916507 scopus 로고    scopus 로고
    • Systemic armed oncolytic and immunologic therapy for cancer with JX-594, a targeted poxvirus expressing GM-CSF
    • Kim JH, Oh JY, Park BH, et al. Systemic armed oncolytic and immunologic therapy for cancer with JX-594, a targeted poxvirus expressing GM-CSF. Mol Ther. 2006;14:361-370.
    • (2006) Mol Ther , vol.14 , pp. 361-370
    • Kim, J.H.1    Oh, J.Y.2    Park, B.H.3
  • 128
    • 57649125119 scopus 로고    scopus 로고
    • An oncolytic adenovirus expressing granulocyte macrophage colony-stimulating factor shows improved specificity and efficacy for treating human solid tumors
    • Lei N, Shen FB, Chang JH, et al. An oncolytic adenovirus expressing granulocyte macrophage colony-stimulating factor shows improved specificity and efficacy for treating human solid tumors. Cancer Gene Ther. 2009;16:33-43.
    • (2009) Cancer Gene Ther , vol.16 , pp. 33-43
    • Lei, N.1    Shen, F.B.2    Chang, J.H.3
  • 129
    • 78049461363 scopus 로고    scopus 로고
    • Efficacy and safety/toxicity study of recombinant vaccinia virus JX-594 in two immunocompetent animal models of glioma
    • Lun X, Chan J, Zhou H, et al. Efficacy and safety/toxicity study of recombinant vaccinia virus JX-594 in two immunocompetent animal models of glioma. Mol Ther. 2010;18:1927-1936.
    • (2010) Mol Ther , vol.18 , pp. 1927-1936
    • Lun, X.1    Chan, J.2    Zhou, H.3
  • 130
    • 34047262198 scopus 로고    scopus 로고
    • Oncolytic immunovirotherapy for melanoma using vesicular stomatitis virus
    • Diaz RM, Galivo F, Kottke T, et al. Oncolytic immunovirotherapy for melanoma using vesicular stomatitis virus. Cancer Res. 2007;67: 2840-2848.
    • (2007) Cancer Res , vol.67 , pp. 2840-2848
    • Diaz, R.M.1    Galivo, F.2    Kottke, T.3
  • 131
    • 79960125220 scopus 로고    scopus 로고
    • Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors
    • Kottke T, Errington F, Pulido J, et al. Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors. Nat Med. 2011;17:854-859.
    • (2011) Nat Med. , vol.17 , pp. 854-859
    • Kottke, T.1    Errington, F.2    Pulido, J.3
  • 132
    • 84859646663 scopus 로고    scopus 로고
    • Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma
    • Pulido J, Kottke T, Thompson J, et al. Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma. Nat Biotechnol. 2012;30:337-343.
    • (2012) Nat Biotechnol , vol.30 , pp. 337-343
    • Pulido, J.1    Kottke, T.2    Thompson, J.3
  • 133
    • 84881310761 scopus 로고    scopus 로고
    • Functional cloning of recurrence-specific antigens identifies molecular targets to treat tumor relapse
    • Boisgerault N, Kottke T, Pulido J, et al. Functional cloning of recurrence-specific antigens identifies molecular targets to treat tumor relapse. Mol Ther. 2013;21:1507-1516.
    • (2013) Mol Ther. , vol.21 , pp. 1507-1516
    • Boisgerault, N.1    Kottke, T.2    Pulido, J.3
  • 134
    • 84875215925 scopus 로고    scopus 로고
    • T cells redirected to EphA2 for the immunotherapy of glioblastoma
    • Chow KKH, Naik S, Kakarla S, et al. T cells redirected to EphA2 for the immunotherapy of glioblastoma. Mol Ther. 2013;21:629-637.
    • (2013) Mol Ther. , vol.21 , pp. 629-637
    • Chow, K.K.H.1    Naik, S.2    Kakarla, S.3
  • 135
    • 0032414023 scopus 로고    scopus 로고
    • Role of fibronectin-stimulated tumor cell migration in glioma invasion in vivo: Clinical significance of fibronectin and fibronectin receptor expressed in human glioma tissues
    • Ohnishi T, Hiraga S, Izumoto S, et al. Role of fibronectin-stimulated tumor cell migration in glioma invasion in vivo: clinical significance of fibronectin and fibronectin receptor expressed in human glioma tissues. Clin Exp Metastasis. 1998;16:729-741.
    • (1998) Clin Exp Metastasis , vol.16 , pp. 729-741
    • Ohnishi, T.1    Hiraga, S.2    Izumoto, S.3
  • 136
    • 70450200778 scopus 로고    scopus 로고
    • The case of oncolytic viruses versus the immune system: Waiting on the judgment of Solomon
    • Prestwich RJ, Errington F, Diaz RM, et al. The case of oncolytic viruses versus the immune system: waiting on the judgment of Solomon. Hum Gene Ther. 2009;20:1119-1132.
    • (2009) Hum Gene Ther , vol.20 , pp. 1119-1132
    • Prestwich, R.J.1    Errington, F.2    Diaz, R.M.3
  • 137
    • 84862766580 scopus 로고    scopus 로고
    • A review of the role of stem cells in the development and treatment of glioma
    • Heywood RM, Marcus HJ, Ryan DJ, et al. A review of the role of stem cells in the development and treatment of glioma. Acta Neurochir (Wien). 2012;154:951-969.
    • (2012) Acta Neurochir (Wien) , vol.154 , pp. 951-969
    • Heywood, R.M.1    Marcus, H.J.2    Ryan, D.J.3
  • 138
    • 84872542148 scopus 로고    scopus 로고
    • Specific elimination of CD133+ tumor cells with targeted oncolytic measles virus
    • Bach P, Abel T, Hoffmann C, et al. Specific elimination of CD133+ tumor cells with targeted oncolytic measles virus. Cancer Res. 2013;73:865-874.
    • (2013) Cancer Res. , vol.73 , pp. 865-874
    • Bach, P.1    Abel, T.2    Hoffmann, C.3
  • 139
    • 84871925433 scopus 로고    scopus 로고
    • Multimechanistic tumor targeted oncolytic virus overcomes resistance in brain tumors
    • Tamura K, Wakimoto H, Agarwal AS, et al. Multimechanistic tumor targeted oncolytic virus overcomes resistance in brain tumors. Mol Ther. 2013;21:68-77.
    • (2013) Mol Ther. , vol.21 , pp. 68-77
    • Tamura, K.1    Wakimoto, H.2    Agarwal, A.S.3
  • 140
    • 84884186952 scopus 로고    scopus 로고
    • YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells
    • Mantwill K, Naumann U, Seznec J, et al. YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells. J Transl Med. 2013;11:216.
    • (2013) J Transl Med. , vol.11 , pp. 216
    • Mantwill, K.1    Naumann, U.2    Seznec, J.3
  • 141
    • 63949085760 scopus 로고    scopus 로고
    • Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo
    • Ulasov IV, Sonabend AM, Nandi S, et al. Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo. Br J Cancer. 2009;100:1154-1164.
    • (2009) Br J Cancer , vol.100 , pp. 1154-1164
    • Ulasov, I.V.1    Sonabend, A.M.2    Nandi, S.3
  • 142
    • 84855486345 scopus 로고    scopus 로고
    • Oncolytic virus-mediatedmanipulation of DNA damage responses: Synergy with chemotherapy in killing glioblastoma stem cells
    • Kanai R, Rabkin SD, Yip S, et al. Oncolytic virus-mediatedmanipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells. J Natl Cancer Inst. 2012;104:42-55.
    • (2012) J Natl Cancer Inst , vol.104 , pp. 42-55
    • Kanai, R.1    Rabkin, S.D.2    Yip, S.3
  • 143
    • 84890127325 scopus 로고    scopus 로고
    • Improved therapeutic effect on malignant glioma with adenoviral suicide gene therapy combined with temozolomide
    • doi:10.1038/gt.2013-46
    • Stedt H, Samaranayake H, Pikkarainen J, et al. Improved therapeutic effect on malignant glioma with adenoviral suicide gene therapy combined with temozolomide. Gene Ther. 2013;20: 1165-1171. doi:10.1038/gt.2013-46.
    • (2013) Gene Ther. , vol.20 , pp. 1165-1171
    • Stedt, H.1    Samaranayake, H.2    Pikkarainen, J.3
  • 144
    • 50549097330 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors augment antitumor efficacy of herpes-based oncolytic viruses
    • Otsuki A, Patel A, Kasai K, et al. Histone deacetylase inhibitors augment antitumor efficacy of herpes-based oncolytic viruses. Mol Ther. 2008;16:1546-1555.
    • (2008) Mol Ther , vol.16 , pp. 1546-1555
    • Otsuki, A.1    Patel, A.2    Kasai, K.3
  • 145
    • 78651234760 scopus 로고    scopus 로고
    • Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors
    • MacTavish H, Diallo J-S, Huang B, et al. Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors. PloS One. 2010;5:e14462.
    • (2010) PloS One , vol.5
    • MacTavish, H.1    Diallo, J.-S.2    Huang, B.3
  • 146
    • 84867740230 scopus 로고    scopus 로고
    • Enhanced antitumor efficacy of telomerase-specific oncolytic adenovirus with valproic acid against human cancer cells
    • Watanabe Y, Hashimoto Y, Kagawa S, et al. Enhanced antitumor efficacy of telomerase-specific oncolytic adenovirus with valproic acid against human cancer cells. Cancer Gene Ther. 2012;19: 767-772.
    • (2012) Cancer Gene Ther , vol.19 , pp. 767-772
    • Watanabe, Y.1    Hashimoto, Y.2    Kagawa, S.3
  • 147
    • 84874768191 scopus 로고    scopus 로고
    • Anti-angiogenic therapy increases intratumoral adenovirus distribution by inducing collagen degradation
    • Thaci B, Ulasov IV, Ahmed AU, et al. Anti-angiogenic therapy increases intratumoral adenovirus distribution by inducing collagen degradation. Gene Ther. 2013;20:318-327.
    • (2013) Gene Ther. , vol.20 , pp. 318-327
    • Thaci, B.1    Ulasov, I.V.2    Ahmed, A.U.3
  • 148
    • 84856957895 scopus 로고    scopus 로고
    • Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma
    • Zhang W, Fulci G, Buhrman JS, et al. Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma. Mol Ther. 2012;20:37-45.
    • (2012) Mol Ther , vol.20 , pp. 37-45
    • Zhang, W.1    Fulci, G.2    Buhrman, J.S.3
  • 149
    • 79957881687 scopus 로고    scopus 로고
    • A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells
    • Kanai R, Wakimoto H, Martuza RL, et al. A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells. Clin Cancer Res. 2011;17:3686-3696.
    • (2011) Clin Cancer Res. , vol.17 , pp. 3686-3696
    • Kanai, R.1    Wakimoto, H.2    Martuza, R.L.3
  • 150
    • 84882454089 scopus 로고    scopus 로고
    • HSV-NIS, an oncolytic herpes simplex virus type 1 encoding human sodium iodide symporter for preclinical prostate cancer radiovirotherapy
    • Li H, Nakashima H, Decklever TD, et al. HSV-NIS, an oncolytic herpes simplex virus type 1 encoding human sodium iodide symporter for preclinical prostate cancer radiovirotherapy. Cancer Gene Ther. 2013;20:478-485.
    • (2013) Cancer Gene Ther. , vol.20 , pp. 478-485
    • Li, H.1    Nakashima, H.2    Decklever, T.D.3
  • 151
    • 84883225023 scopus 로고    scopus 로고
    • An oncolytic vaccinia virus expressing the human sodium iodine symporter prolongs survival and facilitates SPECT/CT imaging in an orthotopic model of malignant pleural mesothelioma
    • Belin LJ, Ady JW, Lewis C, et al. An oncolytic vaccinia virus expressing the human sodium iodine symporter prolongs survival and facilitates SPECT/CT imaging in an orthotopic model of malignant pleural mesothelioma. Surgery. 2013;154: 486-495.
    • (2013) Surgery. , vol.154 , pp. 486-495
    • Belin, L.J.1    Ady, J.W.2    Lewis, C.3
  • 152
    • 84860184807 scopus 로고    scopus 로고
    • Effective radiovirotherapy for malignant gliomas by using oncolytic measles virus strains encoding the sodium iodide symporter (MV-NIS)
    • Opyrchal M, Allen C, Iankov I, et al. Effective radiovirotherapy for malignant gliomas by using oncolytic measles virus strains encoding the sodium iodide symporter (MV-NIS). Hum Gene Ther. 2012;23:419-427.
    • (2012) Hum Gene Ther , vol.23 , pp. 419-427
    • Opyrchal, M.1    Allen, C.2    Iankov, I.3
  • 153
    • 10744233353 scopus 로고    scopus 로고
    • Treatment of progressive or recurrent glioblastoma multiforme in adults with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration: A phase I/II multi-institutional trial
    • Prados MD, McDermott M, Chang SM, et al. Treatment of progressive or recurrent glioblastoma multiforme in adults with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration: a phase I/II multi-institutional trial. J Neurooncol. 2003;65: 269-278.
    • (2003) J Neurooncol , vol.65 , pp. 269-278
    • Prados, M.D.1    McDermott, M.2    Chang, S.M.3
  • 154
    • 85047697641 scopus 로고    scopus 로고
    • Phase i trial of adenovirus-mediated p53 gene therapy for recurrent glioma: Biological and clinical results
    • Lang FF, Bruner JM, Fuller GN, et al. Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results. J Clin Oncol. 2003;21:2508-2518.
    • (2003) J Clin Oncol , vol.21 , pp. 2508-2518
    • Lang, F.F.1    Bruner, J.M.2    Fuller, G.N.3
  • 155
    • 0346243603 scopus 로고    scopus 로고
    • Adenovirus/herpes simplex-thymidine kinase/ganciclovir complex: Preliminary results of a phase i trial in patients with recurrent malignant gliomas
    • Germano IM, Fable J, Gultekin SH, et al. Adenovirus/herpes simplex-thymidine kinase/ganciclovir complex: preliminary results of a phase I trial in patients with recurrent malignant gliomas. J Neurooncol. 2003;65:279-289.
    • (2003) J Neurooncol , vol.65 , pp. 279-289
    • Germano, I.M.1    Fable, J.2    Gultekin, S.H.3
  • 156
    • 0037812853 scopus 로고    scopus 로고
    • Treatment of relapsed malignant glioma with an adenoviral vector containing the herpes simplex thymidine kinase gene followed by ganciclovir
    • Smitt PS, Driesse M, Wolbers J, et al. Treatment of relapsed malignant glioma with an adenoviral vector containing the herpes simplex thymidine kinase gene followed by ganciclovir. Mol Ther. 2003;7:851-858.
    • (2003) Mol Ther , vol.7 , pp. 851-858
    • Smitt, P.S.1    Driesse, M.2    Wolbers, J.3
  • 157
    • 0034136802 scopus 로고    scopus 로고
    • Phase i study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors
    • Trask TW, Trask RP, Aguilar-Cordova E, et al. Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors. Mol Ther. 2000;1:195-203.
    • (2000) Mol Ther , vol.1 , pp. 195-203
    • Trask, T.W.1    Trask, R.P.2    Aguilar-Cordova, E.3
  • 158
    • 0033957146 scopus 로고    scopus 로고
    • Treatment of progressive or recurrent pediatric malignant supratentorial brain tumors with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration
    • Packer RJ, Raffel C, Villablanca JG, et al. Treatment of progressive or recurrent pediatric malignant supratentorial brain tumors with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration. J Neurosurg. 2000;92:249-254.
    • (2000) J Neurosurg , vol.92 , pp. 249-254
    • Packer, R.J.1    Raffel, C.2    Villablanca, J.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.