Molecular stereotactic biopsy technique improves diagnostic accuracy and enables personalized treatment strategies in glioma patients

Acta Neurochirurgica

Volumn 156, Issue 8, 2014, Pages 1427-1440

  Eigenbrod, Sabina ^a   Trabold, Raimund ^a   Brucker, David ^a   Erös, Christian ^a   Egensperger, Rupert ^a   La Fougere, Christian ^a   Göbel, Werner ^b   Rühm, Adrian ^a   Kretzschmar, Hans A ^a   Tonn, Jörg C ^a   Herms, Jochen ^a   Giese, Armin ^a   Kreth, Friedrich W ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b Karl Storz GmbH and Co KG   (Germany)

Author keywords

Biomarkers; Glioma; IDH1 2; MGMT; Molecular stereotactic biopsy

Indexed keywords

BIOLOGICAL MARKER; DNA; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; TEMOZOLOMIDE; DNA METHYLTRANSFERASE; MGMT PROTEIN, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN;

ADJUVANT CHEMOTHERAPY; ADULT; ARTICLE; BRACHYTHERAPY; BRAIN TUMOR; CANCER PALLIATIVE THERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CHROMOSOME 19Q; CHROMOSOME 1P; CHROMOSOME DELETION; CRYOPRESERVATION; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; FEMALE; GENETIC ANALYSIS; GLIOBLASTOMA; GLIOMA; GLIOSARCOMA; HETEROZYGOSITY LOSS; HISTOLOGY; HUMAN; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; METHYLATION; MOLECULAR DIAGNOSIS; MOLECULAR STEREOTACTIC BIOPSY; MORBIDITY; MUTATION; NEUROPATHOLOGIST; PATHOLOGIST; PHOTODYNAMIC THERAPY; PILOCYTIC ASTROCYTOMA; POLYMERASE CHAIN REACTION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROMOTER REGION; PROSPECTIVE STUDY; REPRODUCIBILITY; STEREOTACTIC BIOPSY; WORKFLOW; AGE; BIOPSY; BRAIN NEOPLASMS; DNA METHYLATION; GENETICS; MIDDLE AGED; PATHOLOGY; PERSONALIZED MEDICINE; PROGNOSIS; STEREOTACTIC PROCEDURE; YOUNG ADULT;

ADULT; AGE FACTORS; BIOPSY; BRAIN NEOPLASMS; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; FEMALE; GLIOMA; HUMANS; INDIVIDUALIZED MEDICINE; MALE; MIDDLE AGED; MUTATION; PROGNOSIS; PROMOTER REGIONS, GENETIC; REPRODUCIBILITY OF RESULTS; STEREOTAXIC TECHNIQUES; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS; YOUNG ADULT;

EID: 84904419561     PISSN: 00016268     EISSN: 09420940     Source Type: Journal    
DOI: 10.1007/s00701-014-2073-1     Document Type: Article

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