Frequent loss of chromosome 9, homozygous CDKN2A/p14ARF/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas

Oncogene

Volumn 26, Issue 7, 2007, Pages 1088-1097

  Weber, R G ^a,b   Hoischen, A ^a   Ehrler, M ^a,b   Zipper, P ^c   Kaulich, K ^c   Blaschke, B ^c   Becker, A J ^a   Weber Mangal, S ^d   Jauch, A ^d   Radlwimmer, B ^e   Schramm, J ^f   Wiestler, O D ^e   Lichter, P ^e   Reifenberger, G ^c  

^a UNIVERSITY OF BONN   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^f UNIVERSITY OF BONN   (Germany)

Author keywords

Comparative genomic hybridization; DNA microarray; Molecular genetics; Pleomorphic xanthoastrocytomas; Tumorsuppressor gene

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2B; DNA; MESSENGER RNA; PROTEIN; PROTEIN P14; PROTEIN PATCHED; PROTEIN TSC1; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; ASTROCYTOMA; CHILD; CHROMOSOME 12Q; CHROMOSOME 17; CHROMOSOME 18; CHROMOSOME 19; CHROMOSOME 20; CHROMOSOME 21Q; CHROMOSOME 22; CHROMOSOME 2P; CHROMOSOME 4; CHROMOSOME 4P; CHROMOSOME 5; CHROMOSOME 7; CHROMOSOME 8; CHROMOSOME 9; CHROMOSOME 9P; CHROMOSOME 9Q; CHROMOSOME LOSS; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE DELETION; GENE LOCUS; GENE MAPPING; GENE MUTATION; GENETIC GAIN; GENETIC TRANSCRIPTION; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLECULAR WEIGHT; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PLEOMORPHIC XANTHOASTROCYTOMA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN METHYLATION; TISSUE SECTION; TUMOR CELL; X CHROMOSOME;

ADOLESCENT; ADULT; ASTROCYTOMA; CHILD; CHILD, PRESCHOOL; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 9; CYCLIN-DEPENDENT KINASE INHIBITOR P15; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FEMALE; GENE DELETION; HOMOZYGOTE; HUMANS; MALE; MIDDLE AGED; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P14ARF; TUMOR SUPPRESSOR PROTEINS;

EID: 33847053161     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1209851     Document Type: Article

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