Selective acquisition of IDH1 R132C mutations in astrocytomas associated with Li-Fraumeni syndrome

Acta Neuropathologica

Volumn 117, Issue 6, 2009, Pages 653-656

  Watanabe, Takuya ^a   Vital, Anne ^b   Nobusawa, Sumihito ^a   Kleihues, Paul ^c   Ohgaki, Hiroko ^a  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b UMR 5287   (France)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Astrocytoma; IDH1 mutation; Li Fraumeni syndrome; TP53 germline mutation

Indexed keywords

ISOCITRATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE 1; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTOMA; CLINICAL ARTICLE; FAMILIAL CANCER; GENE MUTATION; HUMAN; MISSENSE MUTATION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SOMATIC MUTATION;

ASTROCYTOMA; BRAIN NEOPLASMS; FAMILY; FEMALE; GENES, P53; GERM-LINE MUTATION; HUMANS; ISOCITRATE DEHYDROGENASE; LI-FRAUMENI SYNDROME; MALE; MUTATION, MISSENSE; PEDIGREE; SEQUENCE ANALYSIS, DNA;

EID: 67349220062     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-009-0528-x     Document Type: Article

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