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Volumn 389, Issue 10082, 2017, Pages 1941-1952

Idiopathic pulmonary fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; NINTEDANIB; PIRFENIDONE; PLACEBO;

EID: 85016515883     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(17)30866-8     Document Type: Review
Times cited : (1386)

References (140)
  • 1
    • 79151482545 scopus 로고    scopus 로고
    • Cancer incidence in five continents
    • (accessed Oct 1, 2016).
    • International Agency for Research on Cancer. Cancer incidence in five continents. http://www.iarc.fr/en/publications/pdfs-online/epi/sp164/CI5volX_Full.pdf, 2014 (accessed Oct 1, 2016).
    • (2014)
  • 2
    • 84940645409 scopus 로고    scopus 로고
    • Global incidence and mortality of idiopathic pulmonary fibrosis: a systematic review
    • Hutchinson, J, Fogarty, A, Hubbard, R, McKeever, T, Global incidence and mortality of idiopathic pulmonary fibrosis: a systematic review. Eur Resp J 46 (2015), 795–806.
    • (2015) Eur Resp J , vol.46 , pp. 795-806
    • Hutchinson, J.1    Fogarty, A.2    Hubbard, R.3    McKeever, T.4
  • 3
    • 84977120300 scopus 로고    scopus 로고
    • Epidemiology and survival of idiopathic pulmonary fibrosis from national data in Canada
    • Hopkins, RB, Fell, C, Dion, G, Kolb, M, Epidemiology and survival of idiopathic pulmonary fibrosis from national data in Canada. Eur Respir J 48 (2016), 187–195.
    • (2016) Eur Respir J , vol.48 , pp. 187-195
    • Hopkins, R.B.1    Fell, C.2    Dion, G.3    Kolb, M.4
  • 4
    • 79952717349 scopus 로고    scopus 로고
    • An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management
    • Raghu, G, Collard, HR, Egan, JJ, et al., for the ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis Study Group. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 183 (2011), 788–824.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 788-824
    • Raghu, G.1    Collard, H.R.2    Egan, J.J.3
  • 5
    • 0034011982 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS)
    • American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med 161 (2000), 646–664.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 646-664
  • 7
    • 79951844263 scopus 로고    scopus 로고
    • Clinical course and prediction of survival in idiopathic pulmonary fibrosis
    • Ley, B, Collard, HR, King, TE, Clinical course and prediction of survival in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 183 (2011), 431–440.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 431-440
    • Ley, B.1    Collard, H.R.2    King, T.E.3
  • 8
    • 0035895243 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy
    • Selman, M, King, TE, Pardo, A for the American Thoracic Society Study Group European Respiratory Society Study Group, American College of Chest Physicians Study Group. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 134 (2001), 136–151.
    • (2001) Ann Intern Med , vol.134 , pp. 136-151
    • Selman, M.1    King, T.E.2    Pardo, A.3
  • 9
    • 84861394764 scopus 로고    scopus 로고
    • Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis
    • Anstrom, KJ, King, TE Jr, Lasky, JA, Martinez, FJ, for the Idiopathic Pulmonary Fibrosis Clinical Research Network Study Group. Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis. N Engl J Med 366 (2012), 1968–1977.
    • (2012) N Engl J Med , vol.366 , pp. 1968-1977
    • Anstrom, K.J.1    King, T.E.2    Lasky, J.A.3    Martinez, F.J.4
  • 11
    • 0035462744 scopus 로고    scopus 로고
    • Occupational dust exposure and the aetiology of cryptogenic fibrosing alveolitis
    • Hubbard, R, Occupational dust exposure and the aetiology of cryptogenic fibrosing alveolitis. Eur Respir J Suppl 18 (2001), 119s–121s.
    • (2001) Eur Respir J Suppl , vol.18 , pp. 119s-121s
    • Hubbard, R.1
  • 12
    • 33744908816 scopus 로고    scopus 로고
    • Is idiopathic pulmonary fibrosis an environmental disease?
    • Taskar, VS, Coultas, DB, Is idiopathic pulmonary fibrosis an environmental disease?. Proc Am Thorac Soc 3 (2006), 293–298.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 293-298
    • Taskar, V.S.1    Coultas, D.B.2
  • 13
    • 34047188508 scopus 로고    scopus 로고
    • Telomerase mutations in families with idiopathic pulmonary fibrosis
    • Armanios, MY, Chen, JJ, Cogan, JD, et al. Telomerase mutations in families with idiopathic pulmonary fibrosis. N Engl J Med 356 (2007), 1317–1326.
    • (2007) N Engl J Med , vol.356 , pp. 1317-1326
    • Armanios, M.Y.1    Chen, J.J.2    Cogan, J.D.3
  • 14
    • 34250614359 scopus 로고    scopus 로고
    • Adult-onset pulmonary fibrosis caused by mutations in telomerase
    • Tsakiri, KD, Cronkhite, JT, Kuan, PJ, et al. Adult-onset pulmonary fibrosis caused by mutations in telomerase. Proc Natl Acad Sci USA 104 (2007), 7552–7557.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 7552-7557
    • Tsakiri, K.D.1    Cronkhite, J.T.2    Kuan, P.J.3
  • 15
    • 58149159548 scopus 로고    scopus 로고
    • Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer
    • Wang, Y, Kuan, PJ, Xing, C, et al. Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer. Am J Hum Genet 84 (2009), 52–59.
    • (2009) Am J Hum Genet , vol.84 , pp. 52-59
    • Wang, Y.1    Kuan, P.J.2    Xing, C.3
  • 16
    • 0035931973 scopus 로고    scopus 로고
    • A mutation in the surfactant protein C gene associated with familial interstitial lung disease
    • Nogee, LM, Dunbar, AE, Wert, SE, Askin, F, Hamvas, A, Whitsett, JA, A mutation in the surfactant protein C gene associated with familial interstitial lung disease. N Engl J Med 344 (2001), 573–579.
    • (2001) N Engl J Med , vol.344 , pp. 573-579
    • Nogee, L.M.1    Dunbar, A.E.2    Wert, S.E.3    Askin, F.4    Hamvas, A.5    Whitsett, J.A.6
  • 17
    • 84929130078 scopus 로고    scopus 로고
    • Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening
    • Stuart, BD, Choi, J, Zaidi, S, et al. Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening. Nat Genet 47 (2015), 512–517.
    • (2015) Nat Genet , vol.47 , pp. 512-517
    • Stuart, B.D.1    Choi, J.2    Zaidi, S.3
  • 18
    • 84924787997 scopus 로고    scopus 로고
    • Rare variants in RTEL1 are associated with familial interstitial pneumonia
    • Cogan, JD, Kropski, JA, Zhao, M, et al. Rare variants in RTEL1 are associated with familial interstitial pneumonia. Am J Respir Crit Care Med 191 (2015), 646–655.
    • (2015) Am J Respir Crit Care Med , vol.191 , pp. 646-655
    • Cogan, J.D.1    Kropski, J.A.2    Zhao, M.3
  • 19
    • 84872054447 scopus 로고    scopus 로고
    • Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis
    • Kropski, JA, Lawson, WE, Young, LR, Blackwell, TS, Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis. Dis Model Mech 6 (2012), 9–17.
    • (2012) Dis Model Mech , vol.6 , pp. 9-17
    • Kropski, J.A.1    Lawson, W.E.2    Young, L.R.3    Blackwell, T.S.4
  • 20
    • 84878686854 scopus 로고    scopus 로고
    • Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
    • Fingerlin, TE, Murphy, E, Zhang, W, et al. Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nat Genet 45 (2013), 613–620.
    • (2013) Nat Genet , vol.45 , pp. 613-620
    • Fingerlin, T.E.1    Murphy, E.2    Zhang, W.3
  • 21
    • 84880043679 scopus 로고    scopus 로고
    • Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study
    • Noth, I, Zhang, Y, Ma, SF, et al. Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study. Lancet Respir Med 1 (2013), 309–317.
    • (2013) Lancet Respir Med , vol.1 , pp. 309-317
    • Noth, I.1    Zhang, Y.2    Ma, S.F.3
  • 22
    • 84988664684 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: a genetic disease that involves mucociliary dysfunction of the peripheral airways
    • Evans, CM, Fingerlin, TE, Schwarz, MI, et al. Idiopathic pulmonary fibrosis: a genetic disease that involves mucociliary dysfunction of the peripheral airways. Physiol Rev 96 (2016), 1567–1591.
    • (2016) Physiol Rev , vol.96 , pp. 1567-1591
    • Evans, C.M.1    Fingerlin, T.E.2    Schwarz, M.I.3
  • 23
    • 79955146233 scopus 로고    scopus 로고
    • A common MUC5B promoter polymorphism and pulmonary fibrosis
    • Seibold, MA, Wise, AL, Speer, MC, et al. A common MUC5B promoter polymorphism and pulmonary fibrosis. N Engl J Med 364 (2011), 1503–1512.
    • (2011) N Engl J Med , vol.364 , pp. 1503-1512
    • Seibold, M.A.1    Wise, A.L.2    Speer, M.C.3
  • 24
    • 84878599042 scopus 로고    scopus 로고
    • MUC5B promoter polymorphism and interstitial lung abnormalities
    • Hunninghake, GM, Hatabu, H, Okajima, Y, et al. MUC5B promoter polymorphism and interstitial lung abnormalities. N Engl J Med 368 (2013), 2192–2200.
    • (2013) N Engl J Med , vol.368 , pp. 2192-2200
    • Hunninghake, G.M.1    Hatabu, H.2    Okajima, Y.3
  • 25
    • 84928329158 scopus 로고    scopus 로고
    • The MUC5B promoter polymorphism is associated with IPF in a Mexican cohort but is rare among Asian ancestries
    • Peljto, AL, Selman, M, Kim, DS, et al. The MUC5B promoter polymorphism is associated with IPF in a Mexican cohort but is rare among Asian ancestries. Chest 147 (2015), 460–464.
    • (2015) Chest , vol.147 , pp. 460-464
    • Peljto, A.L.1    Selman, M.2    Kim, D.S.3
  • 26
    • 84876281483 scopus 로고    scopus 로고
    • Mucin 5B promoter polymorphism is associated with idiopathic pulmonary fibrosis but not with development of lung fibrosis in systemic sclerosis or sarcoidosis
    • Stock, CJ, Sato, H, Fonseca, C, et al. Mucin 5B promoter polymorphism is associated with idiopathic pulmonary fibrosis but not with development of lung fibrosis in systemic sclerosis or sarcoidosis. Thorax 68 (2013), 436–441.
    • (2013) Thorax , vol.68 , pp. 436-441
    • Stock, C.J.1    Sato, H.2    Fonseca, C.3
  • 27
    • 79955144623 scopus 로고    scopus 로고
    • A variant in the promoter of MUC5B and idiopathic pulmonary fibrosis
    • Zhang, Y, Noth, I, Garcia, JGN, Kaminski, N, A variant in the promoter of MUC5B and idiopathic pulmonary fibrosis. N Engl J Med 364 (2011), 1576–1577.
    • (2011) N Engl J Med , vol.364 , pp. 1576-1577
    • Zhang, Y.1    Noth, I.2    Garcia, J.G.N.3    Kaminski, N.4
  • 28
    • 84892563951 scopus 로고    scopus 로고
    • Muc5b is required for airway defence
    • Roy, MG, Livraghi-Butrico, A, Fletcher, AA, et al. Muc5b is required for airway defence. Nature 505 (2015), 412–416.
    • (2015) Nature , vol.505 , pp. 412-416
    • Roy, M.G.1    Livraghi-Butrico, A.2    Fletcher, A.A.3
  • 29
    • 84918777951 scopus 로고    scopus 로고
    • The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis
    • Molyneaux, PL, Cox, MJ, Willis-Owen, SAG, et al. The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 190 (2014), 906–913.
    • (2014) Am J Respir Crit Care Med , vol.190 , pp. 906-913
    • Molyneaux, P.L.1    Cox, M.J.2    Willis-Owen, S.A.G.3
  • 30
    • 84988719552 scopus 로고    scopus 로고
    • MUC5B promoter variant rs35705950 affects MUC5B expression in the distal airways in idiopathic pulmonary fibrosis
    • Nakano, Y, Yang, IV, Walts, A, et al. MUC5B promoter variant rs35705950 affects MUC5B expression in the distal airways in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 193 (2016), 464–466.
    • (2016) Am J Respir Crit Care Med , vol.193 , pp. 464-466
    • Nakano, Y.1    Yang, I.V.2    Walts, A.3
  • 31
    • 84878600828 scopus 로고    scopus 로고
    • Association between the MUC5B promoter polymorphism and survival in patients with idiopathic pulmonary fibrosis
    • Peljto, AL, Zhang, Y, Fingerlin, TE, et al. Association between the MUC5B promoter polymorphism and survival in patients with idiopathic pulmonary fibrosis. JAMA 309 (2013), 2232–2239.
    • (2013) JAMA , vol.309 , pp. 2232-2239
    • Peljto, A.L.1    Zhang, Y.2    Fingerlin, T.E.3
  • 32
    • 84896319764 scopus 로고    scopus 로고
    • Alveolar progenitor and stem cells in lung development, renewal and cancer
    • Desai, TJ, Brownfield, DG, Krasnow, MA, Alveolar progenitor and stem cells in lung development, renewal and cancer. Nature 507 (2014), 190–194.
    • (2014) Nature , vol.507 , pp. 190-194
    • Desai, T.J.1    Brownfield, D.G.2    Krasnow, M.A.3
  • 33
    • 84855511323 scopus 로고    scopus 로고
    • Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition
    • Rock, JR, Barkauskas, CE, Cronce, MJ, et al. Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition. Proc Natl Acad Sci USA 108 (2011), E1475–E1483.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. E1475-E1483
    • Rock, J.R.1    Barkauskas, C.E.2    Cronce, M.J.3
  • 34
    • 85055609527 scopus 로고    scopus 로고
    • Telomere dysfunction in alveolar epithelial cells causes lung remodeling and fibrosis
    • Naikawadi, RP, Disayabutr, S, Mallavia, B, et al. Telomere dysfunction in alveolar epithelial cells causes lung remodeling and fibrosis. JCI Insight, 1, 2016, e86704.
    • (2016) JCI Insight , vol.1 , pp. e86704
    • Naikawadi, R.P.1    Disayabutr, S.2    Mallavia, B.3
  • 35
    • 51349113450 scopus 로고    scopus 로고
    • Short telomeres are a risk factor for idiopathic pulmonary fibrosis
    • Alder, JK, Chen, JJ, Lancaster, L, et al. Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proc Natl Acad Sci USA 105 (2008), 13051–13056.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13051-13056
    • Alder, J.K.1    Chen, J.J.2    Lancaster, L.3
  • 36
    • 84922948913 scopus 로고    scopus 로고
    • Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease
    • Kropski, JA, Pritchett, JM, Zoz, DF, et al. Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease. Am J Respir Crit Care Med 191 (2015), 417–426.
    • (2015) Am J Respir Crit Care Med , vol.191 , pp. 417-426
    • Kropski, J.A.1    Pritchett, J.M.2    Zoz, D.F.3
  • 37
    • 84989814118 scopus 로고    scopus 로고
    • Hyaluronan and TLR4 promote surfactant-protein-C- positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice
    • Liang, J, Zhang, Y, Xie, T, et al. Hyaluronan and TLR4 promote surfactant-protein-C- positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice. Nat Med 22 (2016), 1285–1293.
    • (2016) Nat Med , vol.22 , pp. 1285-1293
    • Liang, J.1    Zhang, Y.2    Xie, T.3
  • 38
    • 65249088418 scopus 로고    scopus 로고
    • WNT1-inducible signaling protein–1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis
    • Königshoff, M, Kramer, M, Balsara, N, et al. WNT1-inducible signaling protein–1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. J Clin Invest 119 (2009), 772–787.
    • (2009) J Clin Invest , vol.119 , pp. 772-787
    • Königshoff, M.1    Kramer, M.2    Balsara, N.3
  • 39
    • 0037385280 scopus 로고    scopus 로고
    • Expression of the developmental Sonic hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes
    • Stewart, GA, Hoyne, GF, Ahmad, SA, et al. Expression of the developmental Sonic hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes. J Pathol 199 (2003), 488–495.
    • (2003) J Pathol , vol.199 , pp. 488-495
    • Stewart, G.A.1    Hoyne, G.F.2    Ahmad, S.A.3
  • 40
    • 33846000634 scopus 로고    scopus 로고
    • Epithelial-mesenchymal interactions in pulmonary fibrosis
    • Horowitz, JC, Thannickal, VJ, Epithelial-mesenchymal interactions in pulmonary fibrosis. Semin Respir Crit Care Med 27 (2006), 600–612.
    • (2006) Semin Respir Crit Care Med , vol.27 , pp. 600-612
    • Horowitz, J.C.1    Thannickal, V.J.2
  • 41
    • 84886304100 scopus 로고    scopus 로고
    • Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis
    • Hung, C, Linn, G, Chow, Y-H, et al. Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis. Am J Respir Crit Care Med 188 (2013), 820–830.
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. 820-830
    • Hung, C.1    Linn, G.2    Chow, Y.-H.3
  • 42
    • 77955914547 scopus 로고    scopus 로고
    • Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
    • Liu, F, Mih, JD, Shea, BS, et al. Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression. J Cell Biol 190 (2010), 693–706.
    • (2010) J Cell Biol , vol.190 , pp. 693-706
    • Liu, F.1    Mih, J.D.2    Shea, B.S.3
  • 43
    • 84868274448 scopus 로고    scopus 로고
    • Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation
    • Booth, AJ, Hadley, R, Cornett, AM, et al. Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation. Am J Respir Crit Care Med 186 (2012), 866–876.
    • (2012) Am J Respir Crit Care Med , vol.186 , pp. 866-876
    • Booth, A.J.1    Hadley, R.2    Cornett, A.M.3
  • 44
    • 84897507640 scopus 로고    scopus 로고
    • Fibrotic extracellular matrix activates a profibrotic positive feedback loop
    • Parker, MW, Rossi, D, Peterson, M, et al. Fibrotic extracellular matrix activates a profibrotic positive feedback loop. J Clin Invest 124 (2014), 1622–1635.
    • (2014) J Clin Invest , vol.124 , pp. 1622-1635
    • Parker, M.W.1    Rossi, D.2    Peterson, M.3
  • 45
    • 84928719514 scopus 로고    scopus 로고
    • Matrix, mesenchyme, and mechanotransduction
    • Tschumperlin, DJ, Matrix, mesenchyme, and mechanotransduction. Ann Am Thorac Soc 12 (2015), S24–S29.
    • (2015) Ann Am Thorac Soc , vol.12 , pp. S24-S29
    • Tschumperlin, D.J.1
  • 46
    • 84983288553 scopus 로고    scopus 로고
    • Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis
    • Chen, H, Qu, J, Huang, X, et al. Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis. Nat Commun 7 (2016), 1–12.
    • (2016) Nat Commun , vol.7 , pp. 1-12
    • Chen, H.1    Qu, J.2    Huang, X.3
  • 47
    • 84865121019 scopus 로고    scopus 로고
    • Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction
    • Huang, X, Yang, N, Fiore, VF, et al. Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction. Am J Respir Cell Mol Biol 47 (2012), 340–348.
    • (2012) Am J Respir Cell Mol Biol , vol.47 , pp. 340-348
    • Huang, X.1    Yang, N.2    Fiore, V.F.3
  • 48
    • 37249044357 scopus 로고    scopus 로고
    • Myofibroblast contraction activates latent TGF- 1 from the extracellular matrix
    • Wipff, PJ, Rifkin, DB, Meister, JJ, Hinz, B, Myofibroblast contraction activates latent TGF- 1 from the extracellular matrix. J Cell Biol 179 (2007), 1311–1323.
    • (2007) J Cell Biol , vol.179 , pp. 1311-1323
    • Wipff, P.J.1    Rifkin, D.B.2    Meister, J.J.3    Hinz, B.4
  • 49
    • 84874609382 scopus 로고    scopus 로고
    • Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
    • Zhou, Y, Huang, X, Hecker, L, et al. Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis. J Clin Invest 123 (2013), 1096–1108.
    • (2013) J Clin Invest , vol.123 , pp. 1096-1108
    • Zhou, Y.1    Huang, X.2    Hecker, L.3
  • 50
    • 0242500879 scopus 로고    scopus 로고
    • Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis
    • Chilosi, M, Poletti, V, Zamò, A, et al. Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis. Am J Pathol 162 (2003), 1495–1502.
    • (2003) Am J Pathol , vol.162 , pp. 1495-1502
    • Chilosi, M.1    Poletti, V.2    Zamò, A.3
  • 51
    • 0031862237 scopus 로고    scopus 로고
    • Number and proliferation of basal and parabasal cells in normal human airway epithelium
    • Boers, JE, Ambergen, AW, Thunnissen, FB, Number and proliferation of basal and parabasal cells in normal human airway epithelium. Am J Respir Crit Care Med 157 (1998), 2000–2006.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 2000-2006
    • Boers, J.E.1    Ambergen, A.W.2    Thunnissen, F.B.3
  • 52
    • 1542319868 scopus 로고    scopus 로고
    • Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium
    • Hong, KU, Reynolds, SD, Watkins, S, Fuchs, E, Stripp, BR, Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol 164 (2004), 577–588.
    • (2004) Am J Pathol , vol.164 , pp. 577-588
    • Hong, K.U.1    Reynolds, S.D.2    Watkins, S.3    Fuchs, E.4    Stripp, B.R.5
  • 53
    • 0036798845 scopus 로고    scopus 로고
    • Abnormal re-epithelialization and lung remodeling in idiopathic pulmonary fibrosis: the role of ΔN-p63
    • Chilosi, M, Poletti, V, Murer, B, et al. Abnormal re-epithelialization and lung remodeling in idiopathic pulmonary fibrosis: the role of ΔN-p63. Lab Invest 82 (2002), 1335–1345.
    • (2002) Lab Invest , vol.82 , pp. 1335-1345
    • Chilosi, M.1    Poletti, V.2    Murer, B.3
  • 54
    • 84945195455 scopus 로고    scopus 로고
    • Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis
    • Korfei, M, Skwarna, S, Henneke, I, et al. Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis. Thorax 70 (2015), 1022–1032.
    • (2015) Thorax , vol.70 , pp. 1022-1032
    • Korfei, M.1    Skwarna, S.2    Henneke, I.3
  • 55
    • 84887454672 scopus 로고    scopus 로고
    • Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis
    • Yang, IV, Coldren, CD, Leach, SM, et al. Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis. Thorax 68 (2013), 114–121.
    • (2013) Thorax , vol.68 , pp. 114-121
    • Yang, I.V.1    Coldren, C.D.2    Leach, S.M.3
  • 56
    • 0035482002 scopus 로고    scopus 로고
    • Predicting survival in idiopathic pulmonary fibrosis: scoring system and survival model
    • King, T, Tooze, J, Schwarz, M, Brown, K, Cherniack, R, Predicting survival in idiopathic pulmonary fibrosis: scoring system and survival model. Am J Respir Crit Care Med 164 (2001), 1171–1181.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1171-1181
    • King, T.1    Tooze, J.2    Schwarz, M.3    Brown, K.4    Cherniack, R.5
  • 57
    • 0034011982 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS)
    • American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med 161 (2000), 646–664.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 646-664
  • 58
    • 0037080547 scopus 로고    scopus 로고
    • American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias
    • American Thoracic Society, European Respiratory Society. American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med 165 (2002), 277–304.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 277-304
  • 60
    • 84881669432 scopus 로고    scopus 로고
    • An official American Thoracic Society/European Respiratory Society statement: update of the international multidisciplinary classification of the idiopathic interstitial pneumonias
    • Travis, WD, Costabel, U, Hansell, DM, et al. An official American Thoracic Society/European Respiratory Society statement: update of the international multidisciplinary classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med 188 (2013), 733–748.
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. 733-748
    • Travis, W.D.1    Costabel, U.2    Hansell, D.M.3
  • 61
    • 10744220627 scopus 로고    scopus 로고
    • Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia
    • Hunninghake, GW, Lynch, DA, Galvin, JR, et al. Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia. Chest 124 (2003), 1215–1223.
    • (2003) Chest , vol.124 , pp. 1215-1223
    • Hunninghake, G.W.1    Lynch, D.A.2    Galvin, J.R.3
  • 62
    • 84979695447 scopus 로고    scopus 로고
    • In-hospital mortality following surgical lung biopsy for interstitial lung disease in the USA: 2000–2011
    • Hutchinson, JP, Fogarty, AW, McKeever, TM, Hubbard, RB, In-hospital mortality following surgical lung biopsy for interstitial lung disease in the USA: 2000–2011. Am J Respir Crit Care Med 193 (2016), 1161–1167.
    • (2016) Am J Respir Crit Care Med , vol.193 , pp. 1161-1167
    • Hutchinson, J.P.1    Fogarty, A.W.2    McKeever, T.M.3    Hubbard, R.B.4
  • 63
    • 77953077453 scopus 로고    scopus 로고
    • Clinical predictors of a diagnosis of idiopathic pulmonary fibrosis
    • Fell, CD, Martinez, FJ, Liu, LX, et al. Clinical predictors of a diagnosis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 181 (2010), 832–837.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 832-837
    • Fell, C.D.1    Martinez, F.J.2    Liu, L.X.3
  • 64
    • 85019556332 scopus 로고    scopus 로고
    • The use of pretest probability increases the value of high-resolution CT in diagnosing usual interstitial pneumonia
    • published online Jan 12.
    • Brownell, R, Moua, T, Henry, TS, et al. The use of pretest probability increases the value of high-resolution CT in diagnosing usual interstitial pneumonia. Thorax, 2017, 10.1136/thoraxjnl-2016-209671 published online Jan 12.
    • (2017) Thorax
    • Brownell, R.1    Moua, T.2    Henry, T.S.3
  • 65
    • 85089912056 scopus 로고    scopus 로고
    • Three-dimensional characterization of fibroblast foci in idiopathic pulmonary fibrosis
    • Jones, MG, Fabre, A, Schneider, P, et al. Three-dimensional characterization of fibroblast foci in idiopathic pulmonary fibrosis. JCI Insight, 1, 2016, e86375.
    • (2016) JCI Insight , vol.1 , pp. e86375
    • Jones, M.G.1    Fabre, A.2    Schneider, P.3
  • 67
    • 5144222998 scopus 로고    scopus 로고
    • Idiopathic interstitial pneumonia: what is the effect of a multidisciplinary approach to diagnosis?
    • Flaherty, KR, King, TE Jr, Raghu, G, et al. Idiopathic interstitial pneumonia: what is the effect of a multidisciplinary approach to diagnosis?. Am J Respir Crit Care Med 170 (2004), 904–910.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 904-910
    • Flaherty, K.R.1    King, T.E.2    Raghu, G.3
  • 68
    • 84880571484 scopus 로고    scopus 로고
    • Prevalence and prognosis of unclassifiable interstitial lung disease
    • Ryerson, CJ, Urbania, TH, Richeldi, L, et al. Prevalence and prognosis of unclassifiable interstitial lung disease. Eur Respir J 42 (2013), 750–757.
    • (2013) Eur Respir J , vol.42 , pp. 750-757
    • Ryerson, C.J.1    Urbania, T.H.2    Richeldi, L.3
  • 69
    • 80051819865 scopus 로고    scopus 로고
    • Ascertainment of individual risk of mortality for patients with idiopathic pulmonary fibrosis
    • Bois du, RM, Weycker, D, Albera, C, et al. Ascertainment of individual risk of mortality for patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 184 (2011), 459–466.
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 459-466
    • Bois du, R.M.1    Weycker, D.2    Albera, C.3
  • 70
    • 84861162888 scopus 로고    scopus 로고
    • A multidimensional index and staging system for idiopathic pulmonary fibrosis
    • Ley, B, Ryerson, CJ, Vittinghoff, E, et al. A multidimensional index and staging system for idiopathic pulmonary fibrosis. Ann Intern Med 156 (2012), 684–691.
    • (2012) Ann Intern Med , vol.156 , pp. 684-691
    • Ley, B.1    Ryerson, C.J.2    Vittinghoff, E.3
  • 71
    • 0037383987 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: a composite physiologic index derived from disease extent observed by computed tomography
    • Wells, AU, Desai, SR, Rubens, MB, et al. Idiopathic pulmonary fibrosis: a composite physiologic index derived from disease extent observed by computed tomography. Am J Respir Crit Care Med 167 (2003), 962–969.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 962-969
    • Wells, A.U.1    Desai, S.R.2    Rubens, M.B.3
  • 72
    • 85020205489 scopus 로고    scopus 로고
    • Genetic evaluation and testing of patients and families with idiopathic pulmonary fibrosis
    • published online Oct 27.
    • Kropski, JA, Young, LR, Cogan, JD, et al. Genetic evaluation and testing of patients and families with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med, 2016, 10.1164/rccm.201609-1820PP published online Oct 27.
    • (2016) Am J Respir Crit Care Med
    • Kropski, J.A.1    Young, L.R.2    Cogan, J.D.3
  • 74
    • 84900443034 scopus 로고    scopus 로고
    • Telomeropathies: an emerging spectrum disorder
    • Holohan, B, Wright, WE, Shay, JW, Telomeropathies: an emerging spectrum disorder. J Cell Biol 205 (2014), 289–299.
    • (2014) J Cell Biol , vol.205 , pp. 289-299
    • Holohan, B.1    Wright, W.E.2    Shay, J.W.3
  • 76
    • 84938125365 scopus 로고    scopus 로고
    • An official ATS/ERS/JRS/ALAT clinical practice guideline: treatment of idiopathic pulmonary fibrosis. An update of the 2011 clinical practice guideline
    • Raghu, G, Rochwerg, B, Zhang, Y, et al. An official ATS/ERS/JRS/ALAT clinical practice guideline: treatment of idiopathic pulmonary fibrosis. An update of the 2011 clinical practice guideline. Am J Respir Crit Care Med 192 (2015), e3–19.
    • (2015) Am J Respir Crit Care Med , vol.192 , pp. e3-19
    • Raghu, G.1    Rochwerg, B.2    Zhang, Y.3
  • 77
    • 84943260551 scopus 로고    scopus 로고
    • Comorbidities in idiopathic pulmonary fibrosis patients: a systematic literature review
    • Raghu, G, Behr, J, Stowasser, S, Comorbidities in idiopathic pulmonary fibrosis patients: a systematic literature review. Eur Respir J 46 (2015), 1113–1130.
    • (2015) Eur Respir J , vol.46 , pp. 1113-1130
    • Raghu, G.1    Behr, J.2    Stowasser, S.3
  • 78
    • 84878438261 scopus 로고    scopus 로고
    • The impact of emphysema in pulmonary fibrosis
    • Cottin, V, The impact of emphysema in pulmonary fibrosis. Eur Respir Rev 22 (2013), 153–157.
    • (2013) Eur Respir Rev , vol.22 , pp. 153-157
    • Cottin, V.1
  • 79
    • 70049102004 scopus 로고    scopus 로고
    • Obstructive sleep apnea is common in idiopathic pulmonary fibrosis
    • Lancaster, LH, Mason, WR, Parnell, JA, et al. Obstructive sleep apnea is common in idiopathic pulmonary fibrosis. Chest 136 (2009), 772–778.
    • (2009) Chest , vol.136 , pp. 772-778
    • Lancaster, L.H.1    Mason, W.R.2    Parnell, J.A.3
  • 80
    • 75149155845 scopus 로고    scopus 로고
    • Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome
    • Cottin, V, Le Pavec, J, Prevot, G, et al. Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome. Eur Respir J 35 (2010), 105–111.
    • (2010) Eur Respir J , vol.35 , pp. 105-111
    • Cottin, V.1    Le Pavec, J.2    Prevot, G.3
  • 81
    • 84877297353 scopus 로고    scopus 로고
    • Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial
    • Raghu, G, Behr, J, Brown, KK, et al. Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial. Ann Intern Med 158 (2013), 641–649.
    • (2013) Ann Intern Med , vol.158 , pp. 641-649
    • Raghu, G.1    Behr, J.2    Brown, K.K.3
  • 82
    • 79959886642 scopus 로고    scopus 로고
    • An investigator-driven study of everolimus in surgical lung biopsy confirmed idiopathic pulmonary fibrosis
    • Malouf, MA, Hopkins, P, Snell, G, Glanville, A, An investigator-driven study of everolimus in surgical lung biopsy confirmed idiopathic pulmonary fibrosis. Respirology 16 (2011), 776–783.
    • (2011) Respirology , vol.16 , pp. 776-783
    • Malouf, M.A.1    Hopkins, P.2    Snell, G.3    Glanville, A.4
  • 83
    • 84863450246 scopus 로고    scopus 로고
    • A placebo-controlled randomized trial of warfarin in idiopathic pulmonary fibrosis
    • Noth, I, Anstrom, KJ, Calvert, SB, et al. A placebo-controlled randomized trial of warfarin in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 186 (2012), 88–95.
    • (2012) Am J Respir Crit Care Med , vol.186 , pp. 88-95
    • Noth, I.1    Anstrom, K.J.2    Calvert, S.B.3
  • 84
    • 80051566676 scopus 로고    scopus 로고
    • BUILD-3: a randomized, controlled trial of bosentan in idiopathic pulmonary fibrosis
    • King, TE Jr, Brown, KK, Raghu, G, et al. BUILD-3: a randomized, controlled trial of bosentan in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 184 (2011), 92–99.
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 92-99
    • King, T.E.1    Brown, K.K.2    Raghu, G.3
  • 86
    • 84888166435 scopus 로고    scopus 로고
    • Macitentan for the treatment of idiopathic pulmonary fibrosis: the randomised controlled MUSIC trial
    • Raghu, G, Million-Rousseau, R, Morganti, A, Perchenet, L, Behr, J, for the MUSIC study group. Macitentan for the treatment of idiopathic pulmonary fibrosis: the randomised controlled MUSIC trial. Eur Respir J 42 (2013), 1622–1632.
    • (2013) Eur Respir J , vol.42 , pp. 1622-1632
    • Raghu, G.1    Million-Rousseau, R.2    Morganti, A.3    Perchenet, L.4    Behr, J.5
  • 87
    • 84901746607 scopus 로고    scopus 로고
    • Randomized trial of acetylcysteine in idiopathic pulmonary fibrosis
    • Martinez, FJ, de Andrade, JA, Anstrom, KJ, King, TE Jr, Raghu, G, for the Idiopathic Pulmonary Fibrosis Clinical Research Network Study Group. Randomized trial of acetylcysteine in idiopathic pulmonary fibrosis. N Engl J Med 370 (2014), 2093–2101.
    • (2014) N Engl J Med , vol.370 , pp. 2093-2101
    • Martinez, F.J.1    de Andrade, J.A.2    Anstrom, K.J.3    King, T.E.4    Raghu, G.5
  • 89
    • 84901810710 scopus 로고    scopus 로고
    • Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis
    • Richeldi, L, Bois du, RM, Raghu, G, et al. Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis. N Engl J Med 370 (2014), 2071–2082.
    • (2014) N Engl J Med , vol.370 , pp. 2071-2082
    • Richeldi, L.1    Bois du, R.M.2    Raghu, G.3
  • 90
    • 84901759236 scopus 로고    scopus 로고
    • A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis
    • King, TE Jr, Bradford, WZ, Castro-Bernardini, S, et al. A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis. N Engl J Med 370 (2014), 2083–2092.
    • (2014) N Engl J Med , vol.370 , pp. 2083-2092
    • King, T.E.1    Bradford, W.Z.2    Castro-Bernardini, S.3
  • 91
    • 79956341531 scopus 로고    scopus 로고
    • Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials
    • Noble, PW, Albera, C, Bradford, WZ, et al. Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. Lancet 377 (2011), 1760–1769.
    • (2011) Lancet , vol.377 , pp. 1760-1769
    • Noble, P.W.1    Albera, C.2    Bradford, W.Z.3
  • 92
    • 49649123154 scopus 로고    scopus 로고
    • BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy
    • Hilberg, F, Roth, GJ, Krssak, M, et al. BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy. Cancer Res 68 (2008), 4774–4782.
    • (2008) Cancer Res , vol.68 , pp. 4774-4782
    • Hilberg, F.1    Roth, G.J.2    Krssak, M.3
  • 93
    • 34248177260 scopus 로고    scopus 로고
    • Inhibition of PDGF, VEGF and FGF signalling attenuates fibrosis
    • Chaudhary, NI, Roth, GJ, Hilberg, F, et al. Inhibition of PDGF, VEGF and FGF signalling attenuates fibrosis. Eur Respir J 29 (2007), 976–985.
    • (2007) Eur Respir J , vol.29 , pp. 976-985
    • Chaudhary, N.I.1    Roth, G.J.2    Hilberg, F.3
  • 94
    • 80053091084 scopus 로고    scopus 로고
    • Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis
    • Richeldi, L, Costabel, U, Selman, M, et al. Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis. N Engl J Med 365 (2011), 1079–1087.
    • (2011) N Engl J Med , vol.365 , pp. 1079-1087
    • Richeldi, L.1    Costabel, U.2    Selman, M.3
  • 95
    • 84975801947 scopus 로고    scopus 로고
    • Efficacy of nintedanib in idiopathic pulmonary fibrosis across prespecified subgroups in INPULSIS
    • Costabel, U, Inoue, Y, Richeldi, L, et al. Efficacy of nintedanib in idiopathic pulmonary fibrosis across prespecified subgroups in INPULSIS. Am J Respir Crit Care Med 193 (2016), 178–185.
    • (2016) Am J Respir Crit Care Med , vol.193 , pp. 178-185
    • Costabel, U.1    Inoue, Y.2    Richeldi, L.3
  • 96
    • 0031738215 scopus 로고    scopus 로고
    • Pirfenidone: a novel pharmacological agent that inhibits leiomyoma cell proliferation and collagen production
    • Lee, BS, Margolin, SB, Nowak, RA, Pirfenidone: a novel pharmacological agent that inhibits leiomyoma cell proliferation and collagen production. J Clin Endocrinol Metab 83 (1998), 219–223.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 219-223
    • Lee, B.S.1    Margolin, S.B.2    Nowak, R.A.3
  • 98
    • 77951160564 scopus 로고    scopus 로고
    • Pirfenidone in idiopathic pulmonary fibrosis
    • Taniguchi, H, Ebina, M, Kondoh, Y, et al. Pirfenidone in idiopathic pulmonary fibrosis. Eur Respir J 35 (2010), 821–829.
    • (2010) Eur Respir J , vol.35 , pp. 821-829
    • Taniguchi, H.1    Ebina, M.2    Kondoh, Y.3
  • 99
    • 84954305088 scopus 로고    scopus 로고
    • Pirfenidone for idiopathic pulmonary fibrosis: analysis of pooled data from three multinational phase 3 trials
    • Noble, PW, Bradford, WZ, Costabel, U, et al. Pirfenidone for idiopathic pulmonary fibrosis: analysis of pooled data from three multinational phase 3 trials. Eur Respir J 47 (2016), 27–30.
    • (2016) Eur Respir J , vol.47 , pp. 27-30
    • Noble, P.W.1    Bradford, W.Z.2    Costabel, U.3
  • 100
    • 85018811809 scopus 로고    scopus 로고
    • Pirfenidone. Annex I: summary of product characteristics
    • (accessed Oct 1, 2016).
    • European Medicines Agency. Pirfenidone. Annex I: summary of product characteristics. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002154/WC500103049.pdf, 2015 (accessed Oct 1, 2016).
    • (2015)
  • 101
    • 84976585919 scopus 로고    scopus 로고
    • Nintedanib. Annex I: summary of product characteristics
    • (accessed Oct 1, 2016).
    • European Medicines Agency. Nintedanib. Annex I: summary of product characteristics. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002569/WC500179970.pdf, 2015 (accessed Oct 1, 2016).
    • (2015)
  • 102
    • 84884952345 scopus 로고    scopus 로고
    • Understanding and managing toxicities of vascular endothelial growth factor (VEGF) inhibitors
    • Schmidinger, M, Understanding and managing toxicities of vascular endothelial growth factor (VEGF) inhibitors. EJC Suppl 11 (2013), 172–191.
    • (2013) EJC Suppl , vol.11 , pp. 172-191
    • Schmidinger, M.1
  • 103
    • 84906805808 scopus 로고    scopus 로고
    • Lung transplantation in idiopathic pulmonary fibrosis: a systematic review of the literature
    • Kistler, KD, Nalysnyk, L, Rotella, P, Esser, D, Lung transplantation in idiopathic pulmonary fibrosis: a systematic review of the literature. BMC Pulm Med, 14, 2014, 788.
    • (2014) BMC Pulm Med , vol.14 , pp. 788
    • Kistler, K.D.1    Nalysnyk, L.2    Rotella, P.3    Esser, D.4
  • 105
    • 84988966334 scopus 로고    scopus 로고
    • Acute exacerbation of idiopathic pulmonary fibrosis. An international working group report
    • Collard, HR, Ryerson, CJ, Corte, TJ, et al. Acute exacerbation of idiopathic pulmonary fibrosis. An international working group report. Am J Respir Crit Care Med 194 (2016), 265–275.
    • (2016) Am J Respir Crit Care Med , vol.194 , pp. 265-275
    • Collard, H.R.1    Ryerson, C.J.2    Corte, T.J.3
  • 106
    • 28144449401 scopus 로고    scopus 로고
    • Histopathologic features and outcome of patients with acute exacerbation of idiopathic pulmonary fibrosis undergoing surgical lung biopsy
    • Parambil, J, Myers, J, Ryu, JH, Histopathologic features and outcome of patients with acute exacerbation of idiopathic pulmonary fibrosis undergoing surgical lung biopsy. Chest 128 (2015), 3310–3315.
    • (2015) Chest , vol.128 , pp. 3310-3315
    • Parambil, J.1    Myers, J.2    Ryu, J.H.3
  • 107
    • 79953652811 scopus 로고    scopus 로고
    • Acute exacerbation of idiopathic pulmonary fibrosis: incidence, risk factors and outcome
    • Song, JW, Hong, SB, Lim, CM, Koh, Y, Kim, DS, Acute exacerbation of idiopathic pulmonary fibrosis: incidence, risk factors and outcome. Eur Respir J 37 (2011), 356–363.
    • (2011) Eur Respir J , vol.37 , pp. 356-363
    • Song, J.W.1    Hong, S.B.2    Lim, C.M.3    Koh, Y.4    Kim, D.S.5
  • 108
    • 84863440748 scopus 로고    scopus 로고
    • Specialist palliative care is more than drugs: a retrospective study of ILD patients
    • Bajwah, S, Higginson, IJ, Ross, JR, et al. Specialist palliative care is more than drugs: a retrospective study of ILD patients. Lung 190 (2012), 215–220.
    • (2012) Lung , vol.190 , pp. 215-220
    • Bajwah, S.1    Higginson, I.J.2    Ross, J.R.3
  • 109
    • 84881546403 scopus 로고    scopus 로고
    • Interventions to improve symptoms and quality of life of patients with fibrotic interstitial lung disease: a systematic review of the literature
    • Bajwah, S, Ross, JR, Peacock, JL, et al. Interventions to improve symptoms and quality of life of patients with fibrotic interstitial lung disease: a systematic review of the literature. Thorax 68 (2013), 867–879.
    • (2013) Thorax , vol.68 , pp. 867-879
    • Bajwah, S.1    Ross, J.R.2    Peacock, J.L.3
  • 111
    • 84893659678 scopus 로고    scopus 로고
    • Pulmonary rehabilitation improves long-term outcomes in interstitial lung disease: a prospective cohort study
    • Ryerson, CJ, Cayou, C, Topp, F, et al. Pulmonary rehabilitation improves long-term outcomes in interstitial lung disease: a prospective cohort study. Respir Med 108 (2014), 203–210.
    • (2014) Respir Med , vol.108 , pp. 203-210
    • Ryerson, C.J.1    Cayou, C.2    Topp, F.3
  • 113
    • 79960681581 scopus 로고    scopus 로고
    • Benefits of pulmonary rehabilitation in idiopathic pulmonary fibrosis
    • Swigris, JJ, Fairclough, DL, Morrison, M, et al. Benefits of pulmonary rehabilitation in idiopathic pulmonary fibrosis. Respir Care 56 (2011), 783–789.
    • (2011) Respir Care , vol.56 , pp. 783-789
    • Swigris, J.J.1    Fairclough, D.L.2    Morrison, M.3
  • 114
    • 85008698220 scopus 로고    scopus 로고
    • Effect of nintedanib in subgroups of idiopathic pulmonary fibrosis by diagnostic criteria
    • Raghu, G, Wells, AU, Nicholson, AG, et al. Effect of nintedanib in subgroups of idiopathic pulmonary fibrosis by diagnostic criteria. Am J Respir Crit Care Med 195 (2017), 78–85.
    • (2017) Am J Respir Crit Care Med , vol.195 , pp. 78-85
    • Raghu, G.1    Wells, A.U.2    Nicholson, A.G.3
  • 115
    • 84966474593 scopus 로고    scopus 로고
    • Multicentre evaluation of multidisciplinary team meeting agreement on diagnosis in diffuse parenchymal lung disease: a case-cohort study
    • Walsh, SLF, Wells, AU, Desai, SR, et al. Multicentre evaluation of multidisciplinary team meeting agreement on diagnosis in diffuse parenchymal lung disease: a case-cohort study. Lancet Respir Med 4 (2016), 557–565.
    • (2016) Lancet Respir Med , vol.4 , pp. 557-565
    • Walsh, S.L.F.1    Wells, A.U.2    Desai, S.R.3
  • 116
    • 84957917892 scopus 로고    scopus 로고
    • Interobserver agreement for the ATS/ERS/JRS/ALAT criteria for a UIP pattern on CT
    • Walsh, SLF, Calandriello, L, Sverzellati, N, Wells, AU, Hansell, DM, for the UIP Observer Consort Study Group. Interobserver agreement for the ATS/ERS/JRS/ALAT criteria for a UIP pattern on CT. Thorax 71 (2016), 45–51.
    • (2016) Thorax , vol.71 , pp. 45-51
    • Walsh, S.L.F.1    Calandriello, L.2    Sverzellati, N.3    Wells, A.U.4    Hansell, D.M.5
  • 117
    • 84981351583 scopus 로고    scopus 로고
    • Bronchoscopic lung cryobiopsy increases diagnostic confidence in the multidisciplinary diagnosis of idiopathic pulmonary fibrosis
    • Tomassetti, S, Wells, AU, Costabel, U, et al. Bronchoscopic lung cryobiopsy increases diagnostic confidence in the multidisciplinary diagnosis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 193 (2016), 745–752.
    • (2016) Am J Respir Crit Care Med , vol.193 , pp. 745-752
    • Tomassetti, S.1    Wells, A.U.2    Costabel, U.3
  • 118
    • 84992560601 scopus 로고    scopus 로고
    • Diagnostic yield and complications of transbronchial lung cryobiopsy for interstitial lung disease: a systematic review and meta-analysis
    • Johannson, KA, Marcoux, VS, Ronksley, PE, Ryerson, CJ, Diagnostic yield and complications of transbronchial lung cryobiopsy for interstitial lung disease: a systematic review and meta-analysis. Ann Am Thorac Soc 13 (2016), 1828–1838.
    • (2016) Ann Am Thorac Soc , vol.13 , pp. 1828-1838
    • Johannson, K.A.1    Marcoux, V.S.2    Ronksley, P.E.3    Ryerson, C.J.4
  • 119
    • 84925427675 scopus 로고    scopus 로고
    • Forced vital capacity in idiopathic pulmonary fibrosis—FDA review of pirfenidone and nintedanib
    • Karimi-Shah, BA, Chowdhury, BA, Forced vital capacity in idiopathic pulmonary fibrosis—FDA review of pirfenidone and nintedanib. N Engl J Med 372 (2015), 1189–1191.
    • (2015) N Engl J Med , vol.372 , pp. 1189-1191
    • Karimi-Shah, B.A.1    Chowdhury, B.A.2
  • 120
    • 84986182380 scopus 로고    scopus 로고
    • Efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis with more preserved lung function
    • Albera, C, Fagan, EA, Glassberg, MK, et al. Efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis with more preserved lung function. Eur Respir J 48 (2016), 843–851.
    • (2016) Eur Respir J , vol.48 , pp. 843-851
    • Albera, C.1    Fagan, E.A.2    Glassberg, M.K.3
  • 121
    • 84961700565 scopus 로고    scopus 로고
    • Effect of continued treatment with pirfenidone following clinically meaningful declines in forced vital capacity: analysis of data from three phase 3 trials in patients with idiopathic pulmonary fibrosis
    • Nathan, SD, Albera, C, Bradford, WZ, et al. Effect of continued treatment with pirfenidone following clinically meaningful declines in forced vital capacity: analysis of data from three phase 3 trials in patients with idiopathic pulmonary fibrosis. Thorax 71 (2016), 429–435.
    • (2016) Thorax , vol.71 , pp. 429-435
    • Nathan, S.D.1    Albera, C.2    Bradford, W.Z.3
  • 122
    • 85018844466 scopus 로고    scopus 로고
    • Technology appraisal guidance TA282. Pirfenidone for treating idioapthic pulmonary fibrosis
    • (accessed Oct 1, 2016).
    • National Institute for Health and Care Excellence. Technology appraisal guidance TA282. Pirfenidone for treating idioapthic pulmonary fibrosis. https://www.nice.org.uk/guidance/ta282, 2013 (accessed Oct 1, 2016).
    • (2013)
  • 123
    • 84952037891 scopus 로고    scopus 로고
    • TOLLIP, MUC5B and the response to N-acetylcysteine among Individuals with idiopathic pulmonary fibrosis
    • Oldham, JM, Ma, SF, Martinez, FJ, et al. TOLLIP, MUC5B and the response to N-acetylcysteine among Individuals with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 192 (2015), 1475–1482.
    • (2015) Am J Respir Crit Care Med , vol.192 , pp. 1475-1482
    • Oldham, J.M.1    Ma, S.F.2    Martinez, F.J.3
  • 125
    • 77950183611 scopus 로고    scopus 로고
    • Does chronic microaspiration cause idiopathic pulmonary fibrosis?
    • Lee, JS, Collard, HR, Raghu, G, et al. Does chronic microaspiration cause idiopathic pulmonary fibrosis?. Am J Med 123 (2010), 304–311.
    • (2010) Am J Med , vol.123 , pp. 304-311
    • Lee, J.S.1    Collard, H.R.2    Raghu, G.3
  • 126
    • 84455201657 scopus 로고    scopus 로고
    • Gastroesophageal reflux therapy is associated with longer survival in patients with idiopathic pulmonary fibrosis
    • Lee, JS, Ryu, JH, Elicker, BM, et al. Gastroesophageal reflux therapy is associated with longer survival in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 184 (2011), 1390–1394.
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 1390-1394
    • Lee, J.S.1    Ryu, J.H.2    Elicker, B.M.3
  • 127
    • 84881367867 scopus 로고    scopus 로고
    • Anti-acid treatment and disease progression in idiopathic pulmonary fibrosis: an analysis of data from three randomised controlled trials
    • Lee, JS, Collard, HR, Anstrom, KJ, et al. Anti-acid treatment and disease progression in idiopathic pulmonary fibrosis: an analysis of data from three randomised controlled trials. Lancet Respir Med 1 (2013), 369–376.
    • (2013) Lancet Respir Med , vol.1 , pp. 369-376
    • Lee, J.S.1    Collard, H.R.2    Anstrom, K.J.3
  • 128
    • 84961876871 scopus 로고    scopus 로고
    • Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis
    • Kreuter, M, Wuyts, W, Renzoni, E, et al. Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis. Lancet Respir Med 4 (2016), 381–389.
    • (2016) Lancet Respir Med , vol.4 , pp. 381-389
    • Kreuter, M.1    Wuyts, W.2    Renzoni, E.3
  • 129
    • 84986237632 scopus 로고    scopus 로고
    • Laparoscopic anti-reflux surgery for idiopathic pulmonary fibrosis at a single centre
    • Raghu, G, Morrow, E, Collins, BF, et al. Laparoscopic anti-reflux surgery for idiopathic pulmonary fibrosis at a single centre. Eur Respir J 48 (2016), 826–832.
    • (2016) Eur Respir J , vol.48 , pp. 826-832
    • Raghu, G.1    Morrow, E.2    Collins, B.F.3
  • 130
    • 84903993583 scopus 로고    scopus 로고
    • Lung microbiome and disease progression in idiopathic pulmonary fibrosis: an analysis of the COMET study
    • Han, MK, Zhou, Y, Murray, S, et al. Lung microbiome and disease progression in idiopathic pulmonary fibrosis: an analysis of the COMET study. Lancet Respir Med 2 (2014), 548–646.
    • (2014) Lancet Respir Med , vol.2 , pp. 548-646
    • Han, M.K.1    Zhou, Y.2    Murray, S.3
  • 131
    • 84872677109 scopus 로고    scopus 로고
    • Treating idiopathic pulmonary fibrosis with the addition of co-trimoxazole: a randomised controlled trial
    • Shulgina, LL, Cahn, APA, Chilvers, ERE, et al. Treating idiopathic pulmonary fibrosis with the addition of co-trimoxazole: a randomised controlled trial. Thorax 68 (2013), 155–162.
    • (2013) Thorax , vol.68 , pp. 155-162
    • Shulgina, L.L.1    Cahn, A.P.A.2    Chilvers, E.R.E.3
  • 132
    • 38049014787 scopus 로고    scopus 로고
    • A double blind randomised placebo controlled pilot study of oral co-trimoxazole in advanced fibrotic lung disease
    • Varney, VA, Parnell, HM, Salisbury, DT, Ratnatheepan, S, Tayar, RB, A double blind randomised placebo controlled pilot study of oral co-trimoxazole in advanced fibrotic lung disease. Pulm Pharmacol Ther 21 (2008), 178–187.
    • (2008) Pulm Pharmacol Ther , vol.21 , pp. 178-187
    • Varney, V.A.1    Parnell, H.M.2    Salisbury, D.T.3    Ratnatheepan, S.4    Tayar, R.B.5
  • 133
    • 84930865108 scopus 로고    scopus 로고
    • Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study
    • Jenkins, RG, Simpson, JK, Saini, G, et al. Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study. Lancet Respir Med 3 (2015), 462–472.
    • (2015) Lancet Respir Med , vol.3 , pp. 462-472
    • Jenkins, R.G.1    Simpson, J.K.2    Saini, G.3
  • 134
    • 43249084804 scopus 로고    scopus 로고
    • MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis
    • Rosas, IO, Richards, TJ, Konishi, K, et al. MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis. PLoS Med, 5, 2008, e93.
    • (2008) PLoS Med , vol.5 , pp. e93
    • Rosas, I.O.1    Richards, T.J.2    Konishi, K.3
  • 135
    • 84890478294 scopus 로고    scopus 로고
    • The toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis
    • O'Dwyer, DN, Armstrong, ME, Trujillo, G, et al. The toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 188 (2013), 1442–1450.
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. 1442-1450
    • O'Dwyer, D.N.1    Armstrong, M.E.2    Trujillo, G.3
  • 136
    • 84885467568 scopus 로고    scopus 로고
    • Peripheral blood mononuclear cell gene expression profiles predict poor outcome in idiopathic pulmonary fibrosis
    • Herazo-Maya, JD, Noth, I, Duncan, SR, et al. Peripheral blood mononuclear cell gene expression profiles predict poor outcome in idiopathic pulmonary fibrosis. Sci Transl Med, 5, 2013, 205ra136.
    • (2013) Sci Transl Med , vol.5 , pp. 205ra136
    • Herazo-Maya, J.D.1    Noth, I.2    Duncan, S.R.3
  • 137
    • 65249160219 scopus 로고    scopus 로고
    • Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis
    • Prasse, A, Probst, C, Bargagli, E, et al. Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 179 (2009), 717–723.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 717-723
    • Prasse, A.1    Probst, C.2    Bargagli, E.3
  • 138
    • 84965062194 scopus 로고    scopus 로고
    • Safety and tolerability of acetylcysteine and pirfenidone combination therapy in idiopathic pulmonary fibrosis: a randomised, double-blind, placebo-controlled, phase 2 trial
    • Behr, J, Bendstrup, E, Crestani, B, et al. Safety and tolerability of acetylcysteine and pirfenidone combination therapy in idiopathic pulmonary fibrosis: a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Respir Med 4 (2016), 445–453.
    • (2016) Lancet Respir Med , vol.4 , pp. 445-453
    • Behr, J.1    Bendstrup, E.2    Crestani, B.3
  • 139
    • 84928998844 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of nintedanib and pirfenidone in idiopathic pulmonary fibrosis
    • Ogura, A, Taniguchi, H, Azuma, A, et al. Safety and pharmacokinetics of nintedanib and pirfenidone in idiopathic pulmonary fibrosis. Eur Respir J 45 (2015), 1382–1392.
    • (2015) Eur Respir J , vol.45 , pp. 1382-1392
    • Ogura, A.1    Taniguchi, H.2    Azuma, A.3
  • 140
    • 84925060829 scopus 로고    scopus 로고
    • Fibrosis—a common pathway to organ injury and failure
    • Rockey, DC, Bell, PD, Hill, JA, Fibrosis—a common pathway to organ injury and failure. N Engl J Med 372 (2015), 1138–1149.
    • (2015) N Engl J Med , vol.372 , pp. 1138-1149
    • Rockey, D.C.1    Bell, P.D.2    Hill, J.A.3


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