메뉴 건너뛰기




Volumn 124, Issue 4, 2014, Pages 1622-1635

Fibrotic extracellular matrix activates a profibrotic positive feedback loop

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA 29; SCLEROPROTEIN; TRANSCRIPTOME;

EID: 84897507640     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI71386     Document Type: Article
Times cited : (446)

References (62)
  • 1
    • 0028926188 scopus 로고
    • Mechanical properties of the extracellular matrix influence fibronectin fibril assembly in vitro
    • Halliday NL, Tomasek JJ. Mechanical properties of the extracellular matrix influence fibronectin fibril assembly in vitro. Exp Cell Res. 1995;217(1):109-117.
    • (1995) Exp Cell Res , vol.217 , Issue.1 , pp. 109-117
    • Halliday, N.L.1    Tomasek, J.J.2
  • 2
    • 0344074569 scopus 로고    scopus 로고
    • Cell locomotion and focal adhesions are regulated by the mechanical properties of the substrate
    • Pelham RJ Jr, Wang Y. Cell locomotion and focal adhesions are regulated by the mechanical properties of the substrate. Biol Bull. 1998;194(3):348-350. (Pubitemid 28338467)
    • (1998) Biological Bulletin , vol.194 , Issue.3 , pp. 348-350
    • Pelham Jr., R.J.1    Wang, Y.-L.2
  • 3
    • 0023695630 scopus 로고
    • Influence of the extracellular matrix on the proliferative response of human skin fibroblasts to serum and purified platelet-derived growth factor
    • Rhudy RW, McPherson JM. Influence of the extracellular matrix on the proliferative response of human skin fibroblasts to serum and purified platelet-derived growth factor. J Cell Physiol. 1988;137(1):185-191.
    • (1988) J Cell Physiol , vol.137 , Issue.1 , pp. 185-191
    • Rhudy, R.W.1    McPherson, J.M.2
  • 4
    • 0019230340 scopus 로고
    • Cell proliferation and migration on collagen substrata in vitro
    • Schor SL. Cell proliferation and migration on collagen substrata in vitro. J Cell Sci. 1980;41(1):159-175. (Pubitemid 10054369)
    • (1980) Journal of Cell Science , vol.41 , pp. 159-175
    • Schor, S.L.1
  • 5
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • DOI 10.1038/nature03096
    • Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004;432(7015):332-337. (Pubitemid 39551661)
    • (2004) Nature , vol.432 , Issue.7015 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 6
    • 33646384428 scopus 로고    scopus 로고
    • Fibroblasts in cancer
    • Kalluri R, Zeisberg M. Fibroblasts in cancer. Nat Rev. 2006;6(5):392-401.
    • (2006) Nat Rev , vol.6 , Issue.5 , pp. 392-401
    • Kalluri, R.1    Zeisberg, M.2
  • 7
    • 0037052448 scopus 로고    scopus 로고
    • Development: Stromal effects on mammary gland development and breast cancer
    • DOI 10.1126/science.1067431
    • Wiseman BS, Werb Z. Stromal effects on mammary gland development and breast cancer. Science 2002;296(5570):1046-1049. (Pubitemid 34517108)
    • (2002) Science , vol.296 , Issue.5570 , pp. 1046-1049
    • Wiseman, B.S.1    Werb, Z.2
  • 8
    • 84863702343 scopus 로고    scopus 로고
    • Mechanisms of fibrosis: Therapeutic translation for fibrotic disease
    • Wynn TA, Ramalingam TR. Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat Med. 2012;18(7):1028-1040.
    • (2012) Nat Med , vol.18 , Issue.7 , pp. 1028-1040
    • Wynn, T.A.1    Ramalingam, T.R.2
  • 9
    • 84859073207 scopus 로고    scopus 로고
    • Recent developments in myofibroblast biology: Paradigms for connective tissue remodeling
    • Hinz B, et al. Recent developments in myofibroblast biology: paradigms for connective tissue remodeling. Am J Pathol. 2012;180(4):1340-1355.
    • (2012) Am J Pathol , vol.180 , Issue.4 , pp. 1340-1355
    • Hinz, B.1
  • 10
    • 0035895243 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
    • Selman M, et al. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med. 2001;134(2):136-151. (Pubitemid 32096342)
    • (2001) Annals of Internal Medicine , vol.134 , Issue.2 , pp. 136-151
    • Selman, M.1    King Jr., T.E.2    Pardo, A.3
  • 11
    • 9344223323 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: New insights into pathogenesis
    • DOI 10.1016/j.ccm.2004.04.003, PII S0272523104000474
    • Noble PW, et al. Idiopathic pulmonary fibrosis: new insights into pathogenesis. Clin Chest Med. 2004;25(4):749-758. (Pubitemid 39556507)
    • (2004) Clinics in Chest Medicine , vol.25 , Issue.4 SPEC.ISS. , pp. 749-758
    • Noble, P.W.1    Homer, R.J.2
  • 12
    • 82755161052 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis
    • King TE, Pardo A, Selman M. Idiopathic pulmonary fibrosis. Lancet. 2011;378(9807):1949-1961.
    • (2011) Lancet , vol.378 , Issue.9807 , pp. 1949-1961
    • King, T.E.1    Pardo, A.2    Selman, M.3
  • 15
    • 33644985711 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Natural history and prognosis
    • Noble PW. Idiopathic pulmonary fibrosis: natural history and prognosis. Clin Chest Med. 2006;27(1):S11-S16.
    • (2006) Clin Chest Med , vol.27 , Issue.1
    • Noble, P.W.1
  • 20
    • 25444467151 scopus 로고    scopus 로고
    • Growth factors in idiopathic pulmonary fibrosis: Relative roles
    • Allen JT, Spiteri MA. Growth factors in idiopathic pulmonary fibrosis: relative roles. Respir Res. 2001;3:13.
    • (2001) Respir Res , vol.3 , pp. 13
    • Allen, J.T.1    Spiteri, M.A.2
  • 21
    • 58849094483 scopus 로고    scopus 로고
    • Mmp expression and abnormal lung permeability are important determinants of outcome in ipf
    • McKeown S, Richter AG, O'Kane C, McAuley DF, Thickett D. Mmp expression and abnormal lung permeability are important determinants of outcome in ipf. Eur Respir J. 2009;33(1):77-84.
    • (2009) Eur Respir J , vol.33 , Issue.1 , pp. 77-84
    • McKeown, S.1    Richter, A.G.2    O'Kane, C.3    McAuley, D.F.4    Thickett, D.5
  • 22
    • 13244254138 scopus 로고    scopus 로고
    • Insulin-like growth factor binding proteins 3 and 5 are overexpressed in idiopathic pulmonary fibrosis and contribute to extracellular matrix deposition
    • Pilewski JM, Liu L, Henry AC, Knauer AV, Feghali- Bostwick CA. Insulin-like growth factor binding proteins 3 and 5 are overexpressed in idiopathic pulmonary fibrosis and contribute to extracellular matrix deposition. Am J Pathol. 2005;166(2):399-407. (Pubitemid 40189037)
    • (2005) American Journal of Pathology , vol.166 , Issue.2 , pp. 399-407
    • Pilewski, J.M.1    Liu, L.2    Henry, A.C.3    Knauer, A.V.4    Feghali-Bostwick, C.A.5
  • 23
  • 24
    • 78649737455 scopus 로고    scopus 로고
    • The extracellular matrix at a glance
    • Frantz C, Stewart KM, Weaver VM. The extracellular matrix at a glance. J Cell Sci. 2010;123(24):4195-4200.
    • (2010) J Cell Sci , vol.123 , Issue.24 , pp. 4195-4200
    • Frantz, C.1    Stewart, K.M.2    Weaver, V.M.3
  • 25
    • 0034038922 scopus 로고    scopus 로고
    • Role of mechanical factors in modulating cardiac fibroblast function and extracellular matrix synthesis
    • DOI 10.1016/S0008-6363(00)00030-4, PII S0008636300000304
    • MacKenna D, Summerour SR, Villarreal FJ. Role of mechanical factors in modulating cardiac fibroblast function and extracellular matrix synthesis. Cardiovasc Res. 2000;46(2):257-263. (Pubitemid 30204597)
    • (2000) Cardiovascular Research , vol.46 , Issue.2 , pp. 257-263
    • MacKenna, D.1    Summerour, S.R.2    Villarreal, F.J.3
  • 26
    • 84874609382 scopus 로고    scopus 로고
    • Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
    • Zhou Y, et al. Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis. J Clin Invest. 2013;123(3):1096-1108.
    • (2013) J Clin Invest , vol.123 , Issue.3 , pp. 1096-1108
    • Zhou, Y.1
  • 28
    • 52449088850 scopus 로고    scopus 로고
    • Fibrotic myofibroblasts manifest genome-wide derangements of translational control
    • Larsson O, et al. Fibrotic myofibroblasts manifest genome-wide derangements of translational control. PLoS One 2008;3(9): e3220.
    • (2008) PLoS One , vol.3 , Issue.9
    • Larsson, O.1
  • 29
    • 77955638726 scopus 로고    scopus 로고
    • Genomic phenotype of non-cultured pulmonary fibroblasts in idiopathic pulmonary fibrosis
    • Emblom-Callahan M, et al. Genomic phenotype of non-cultured pulmonary fibroblasts in idiopathic pulmonary fibrosis. Genomics 2010;96(3):134-145.
    • (2010) Genomics , vol.96 , Issue.3 , pp. 134-145
    • Emblom-Callahan, M.1
  • 30
    • 67650721786 scopus 로고    scopus 로고
    • Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis
    • Konishi K, et al. Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2009;180(2):167-175.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.2 , pp. 167-175
    • Konishi, K.1
  • 31
    • 62549134121 scopus 로고    scopus 로고
    • Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
    • Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science 2009;324(5924):218-223.
    • (2009) Science , vol.324 , Issue.5924 , pp. 218-223
    • Ingolia, N.T.1    Ghaemmaghami, S.2    Newman, J.R.3    Weissman, J.S.4
  • 32
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B Stat Methodol. 1995;57(1):289-300.
    • (1995) J R Stat Soc Ser B Stat Methodol , vol.57 , Issue.1 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 33
    • 70450164273 scopus 로고    scopus 로고
    • Wnt5a is a regulator of fibroblast proliferation and resistance to apoptosis
    • Vuga L, et al. Wnt5a is a regulator of fibroblast proliferation and resistance to apoptosis. Am J Respir Cell Mol Biol. 2009;41(5):583-589.
    • (2009) Am J Respir Cell Mol Biol , vol.41 , Issue.5 , pp. 583-589
    • Vuga, L.1
  • 34
    • 78650723802 scopus 로고    scopus 로고
    • Identification of differential translation in genome wide studies
    • Larsson O, Sonenberg N, Nadon R. Identification of differential translation in genome wide studies. Proc Natl Acad Sci U S A. 2010;107(50):21487-21492.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.50 , pp. 21487-21492
    • Larsson, O.1    Sonenberg, N.2    Nadon, R.3
  • 35
    • 79955753537 scopus 로고    scopus 로고
    • anota: Analysis of differential translation in genome-wide studies
    • Larsson O, Sonenberg N, Nadon R. anota: analysis of differential translation in genome-wide studies. Bioinformatics 2011;27(10):1440-1441.
    • (2011) Bioinformatics , vol.27 , Issue.10 , pp. 1440-1441
    • Larsson, O.1    Sonenberg, N.2    Nadon, R.3
  • 36
    • 84878600428 scopus 로고    scopus 로고
    • Genome-wide analysis of host mrna translation during hepatitis c virus infection
    • Colman H, et al. Genome-wide analysis of host mrna translation during hepatitis c virus infection. J Virol. 2013;87(12):6668-6677.
    • (2013) J Virol , vol.87 , Issue.12 , pp. 6668-6677
    • Colman, H.1
  • 38
    • 84868274448 scopus 로고    scopus 로고
    • Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation
    • Booth A, et al. Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation. Am J Respir Crit Care Med. 2012;186(9):866-876.
    • (2012) Am J Respir Crit Care Med , vol.186 , Issue.9 , pp. 866-876
    • Booth, A.1
  • 39
    • 60149091189 scopus 로고    scopus 로고
    • Regulation of translation initiation in eukaryotes: Mechanisms and biological targets
    • Sonenberg N, Hinnebusch AG. Regulation of translation initiation in eukaryotes: mechanisms and biological targets. Cell. 2009;136(4):731-745.
    • (2009) Cell , vol.136 , Issue.4 , pp. 731-745
    • Sonenberg, N.1    Hinnebusch, A.G.2
  • 40
    • 80051655553 scopus 로고    scopus 로고
    • mir-29 is a major regulator of genes associated with pulmonary fibrosis
    • Cushing L, et al. mir-29 is a major regulator of genes associated with pulmonary fibrosis. Am J Respir Cell Mol Biol. 2011;45(2):287-294.
    • (2011) Am J Respir Cell Mol Biol , vol.45 , Issue.2 , pp. 287-294
    • Cushing, L.1
  • 41
    • 79952790398 scopus 로고    scopus 로고
    • Micrornas in idiopathic pulmonary fibrosis
    • Pandit K, Milosevic J, Kaminski N. Micrornas in idiopathic pulmonary fibrosis. Transl Res. 2011;157(4):191-199.
    • (2011) Transl Res , vol.157 , Issue.4 , pp. 191-199
    • Pandit, K.1    Milosevic, J.2    Kaminski, N.3
  • 42
    • 79956322553 scopus 로고    scopus 로고
    • Global quantification of mammalian gene expression control
    • Schwanhäusser B, et al. Global quantification of mammalian gene expression control. Nature. 2011;473(7347):337-342.
    • (2011) Nature , vol.473 , Issue.7347 , pp. 337-342
    • Schwanhäusser, B.1
  • 43
    • 79959338409 scopus 로고    scopus 로고
    • A micro rna processing defect in rapidly progressing idiopathic pulmonary fibrosis
    • Oak SR, et al. A micro rna processing defect in rapidly progressing idiopathic pulmonary fibrosis. PloS One. 2011;6(6):e21253.
    • (2011) PloS One , vol.6 , Issue.6
    • Oak, S.R.1
  • 44
    • 77952946050 scopus 로고    scopus 로고
    • Microrna-29, a key regulator of collagen expression in systemic sclerosis
    • Maurer B, et al. Microrna-29, a key regulator of collagen expression in systemic sclerosis. Arthritis Rheum. 2010;62(6):1733-1743.
    • (2010) Arthritis Rheum , vol.62 , Issue.6 , pp. 1733-1743
    • Maurer, B.1
  • 45
    • 79960946532 scopus 로고    scopus 로고
    • Tgf-β/smad3 signaling promotes renal fibrosis by inhibiting mir-29
    • Qin W, et al. Tgf-β/smad3 signaling promotes renal fibrosis by inhibiting mir-29. J Am Soc Nephrol. 2011;22(8):1462-1474.
    • (2011) J Am Soc Nephrol , vol.22 , Issue.8 , pp. 1462-1474
    • Qin, W.1
  • 46
    • 51349141401 scopus 로고    scopus 로고
    • Dysregulation of micrornas after myocardial infarction reveals a role of mir-29 in cardiac fibrosis
    • Van Rooij E, et al. Dysregulation of micrornas after myocardial infarction reveals a role of mir-29 in cardiac fibrosis. Proc Natl Acad Sci U S A. 2008;105(35):13027-13032.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.35 , pp. 13027-13032
    • Van Rooij, E.1
  • 47
    • 84861916258 scopus 로고    scopus 로고
    • mir-29 inhibits bleomycin-induced pulmonary fibrosis in mice
    • Xiao J, et al. mir-29 inhibits bleomycin-induced pulmonary fibrosis in mice. Mol Ther. 2012;20(6):1251-1260.
    • (2012) Mol Ther , vol.20 , Issue.6 , pp. 1251-1260
    • Xiao, J.1
  • 48
    • 84876270973 scopus 로고    scopus 로고
    • Mir-29 mediates tgf? 1- induced extracellular matrix synthesis through activation of pi3k-akt pathway in human lung fibroblasts
    • Yang T, et al. Mir-29 mediates tgf ? 1- induced extracellular matrix synthesis through activation of pi3k-akt pathway in human lung fibroblasts. J Cell Biochem. 2013;114(6):1336-1342.
    • (2013) J Cell Biochem , vol.114 , Issue.6 , pp. 1336-1342
    • Yang, T.1
  • 49
    • 58149177166 scopus 로고    scopus 로고
    • Reactome knowledgebase of human biological pathways and processes
    • Matthews L, et al. Reactome knowledgebase of human biological pathways and processes. Nucleic Acids Res. 2009;37(suppl 1):D619-D622.
    • (2009) Nucleic Acids Res , vol.37 , Issue.SUPPL. 1
    • Matthews, L.1
  • 50
    • 0022608759 scopus 로고
    • Repopulation of a human alveolar matrix by adult rat type II pneumocytes in vitro. A novel system for type II pneumocyte culture
    • Lwebuga-Mukasa JS, Ingbar DH, Madri JA. Repopulation of a human alveolar matrix by adult rat type ii pneumocytes in vitro: a novel system for type ii pneumocyte culture. Exp Cell Res. 1986;162(2):423-435. (Pubitemid 16131242)
    • (1986) Experimental Cell Research , vol.162 , Issue.2 , pp. 423-435
    • Lwebuga-Mukasa, J.S.1    Ingbar, D.H.2    Madri, J.A.3
  • 53
    • 0348143180 scopus 로고    scopus 로고
    • A random variance model for detection of differential gene expression in small microarray experiments
    • DOI 10.1093/bioinformatics/btg345
    • Wright GW, Simon RM. A random variance model for detection of differential gene expression in small microarray experiments. Bioinformatics 2003;19(18):2448-2455. (Pubitemid 38016644)
    • (2003) Bioinformatics , vol.19 , Issue.18 , pp. 2448-2455
    • Wright, G.W.1    Simon, R.M.2
  • 55
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • DOI 10.1016/j.cell.2004.12.035, PII S0092867404012607
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microrna targets. Cell. 2005;120(1):15-20. (Pubitemid 40094598)
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 56
    • 0023711798 scopus 로고
    • Calcium phosphate-mediated gene transfer: A highly efficient transfection system for stably transforming cells with plasmid dna
    • Chen C, Okayama H. Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid dna. Biotechniques. 1987;6(7):632-638.
    • (1987) Biotechniques , vol.6 , Issue.7 , pp. 632-638
    • Chen, C.1    Okayama, H.2
  • 57
  • 58
    • 0031686754 scopus 로고    scopus 로고
    • High-titer human immunodeficiency virus type 1-based vector systems for gene delivery into nondividing cells
    • Mochizuki H, Schwartz JP, Tanaka K, Brady RO, Reiser J. High-titer human immunodeficiency virus type 1-based vector systems for gene delivery into nondividing cells. J Virol. 1998;72(11):8873-8883. (Pubitemid 28471831)
    • (1998) Journal of Virology , vol.72 , Issue.11 , pp. 8873-8883
    • Mochizuki, H.1    Schwartz, J.P.2    Tanaka, K.3    Brady, R.O.4    Reiser, J.5
  • 62
    • 79951936473 scopus 로고    scopus 로고
    • Creating higher titer lentivirus with caffeine
    • Ellis BL, Potts PR, Porteus MH. Creating higher titer lentivirus with caffeine. Hum Gene Ther. 2010;22(1):93-100.
    • (2010) Hum Gene Ther , vol.22 , Issue.1 , pp. 93-100
    • Ellis, B.L.1    Potts, P.R.2    Porteus, M.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.