Gastroesophageal reflux therapy is associated with longer survival in patients with idiopathic pulmonary fibrosis

American Journal of Respiratory and Critical Care Medicine

Volumn 184, Issue 12, 2011, Pages 1390-1394

  Lee, Joyce S ^a   Ryu, Jay H ^b   Elicker, Brett M ^a   Lydell, Carmen P ^a   Jones, Kirk D ^a   Wolters, Paul J ^a   King Jr , Talmadge E ^a   Collard, Harold R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Idiopathic interstitial pneumonia; Pulmonary fibrosis; Respiratory aspiration; Survival

Indexed keywords

ACETYLCYSTEINE; AZATHIOPRINE; HISTAMINE H2 RECEPTOR ANTAGONIST; PREDNISONE; PROTON PUMP INHIBITOR; WARFARIN;

AGED; ARTICLE; ASPIRATION; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; COUGHING; DISEASE ASSOCIATION; DYSPNEA; FEMALE; FIBROSING ALVEOLITIS; GASTROESOPHAGEAL REFLUX; HEARTBURN; HUMAN; INTERSTITIAL LUNG DISEASE; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; PREDICTOR VARIABLE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCORING SYSTEM; STOMACH FUNDOPLICATION; SURVIVAL TIME; TOTAL LUNG CAPACITY; UNIVERSITY HOSPITAL;

AGED; CASE-CONTROL STUDIES; COMORBIDITY; FEMALE; FUNDOPLICATION; GASTROESOPHAGEAL REFLUX; HISTAMINE H2 ANTAGONISTS; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MALE; PROPORTIONAL HAZARDS MODELS; PROTON PUMP INHIBITORS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 84455201657     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201101-0138OC     Document Type: Article

References (16)

1. Raghu G, Collard HR, Egan JJ, Martinez FJ, Behr J, Brown KK, Colby TV, Cordier JF, Flaherty KR, Lasky JA, et al. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 2011;183:788-824.
2. Selman M, King TE, Pardo A. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 2001;134:136-151. (Pubitemid 32096342)
3. Mays EE, Dubois JJ, Hamilton GB. Pulmonary fibrosis associated with tracheobronchial aspiration. A study of the frequency of hiatal hernia and gastroesophageal reflux in interstitial pulmonary fibrosis of obscure etiology. Chest 1976;69:512-515.
4. Lee JS, Collard HR, Raghu G, Sweet MP, Hays SR, Campos GM, Golden JA, King TE Jr. Does chronic microaspiration cause idiopathic pulmonary fibrosis? Am J Med 2010;123:304-311.
5. Raghu G, Yang ST, Spada C, Hayes J, Pellegrini CA. Sole treatment of acid gastroesophageal reflux in idiopathic pulmonary fibrosis: a case series. Chest 2006;129:794-800.
6. Pearson JE, Wilson RS. Diffuse pulmonary fibrosis and hiatus hernia. Thorax 1971;26:300-305.
7. Downing TE, Sporn TA, Bollinger RR, Davis RD, Parker W, Lin SS. Pulmonary histopathology in an experimental model of chronic aspiration is independent of acidity. Exp Biol Med (Maywood) 2008; 233:1202-1212.
8. Appel JZ III, Lee SM, Hartwig MG, Li B, Hsieh CC, Cantu E III, Yoon Y, Lin SS, Parker W, Davis RD. Characterization of the innate immune response to chronic aspiration in a novel rodent model. Respir Res 2007;8:87.
9. Linden PA, Gilbert RJ, Yeap BY, Boyle K, Deykin A, Jaklitsch MT, Sugarbaker DJ, Bueno R. Laparoscopic fundoplication in patients with end-stage lung disease awaiting transplantation. J Thorac Cardiovasc Surg 2006;131:438-446. (Pubitemid 43121569)
10. Tobin RW, Pope CE II, Pellegrini CA, Emond MJ, Sillery J, Raghu G. Increased prevalence of gastroesophageal reflux in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 1998;158: 1804-1808. (Pubitemid 29008818)
11. Patti MG, Tedesco P, Golden J, Hays S, Hoopes C, Meneghetti A, Damani T, Way LW. Idiopathic pulmonary fibrosis: How often is it really idiopathic? J Gastrointest Surg 2005;9:1053-1056, discussion 1056-1058.
12. Raghu G, Freudenberger TD, Yang S, Curtis JR, Spada C, Hayes J, Sillery JK, Pope CE II, Pellegrini CA. High prevalence of abnormal acid gastro-oesophageal reflux in idiopathic pulmonary fibrosis. Eur Respir J 2006;27:136-142. (Pubitemid 43092677)
13. Salvioli B, Belmonte G, Stanghellini V, Baldi E, Fasano L, Pacilli AM, De Giorgio R, Barbara G, Bini L, Cogliandro R, et al. Gastrooesophageal reflux and interstitial lung disease. Dig Liver Dis 2006; 38:879-884. (Pubitemid 44743373)
14. Sweet MP, Patti MG, Leard LE, Golden JA, Hays SR, Hoopes C, Theodore PR. Gastroesophageal reflux in patients with idiopathic pulmonary fibrosis referred for lung transplantation. J Thorac Cardiovasc Surg 2007;133:1078-1084. (Pubitemid 46435907)
15. Best AC, Meng J, Lynch AM, Bozic CM, Miller D, Grunwald GK, Lynch DA. Idiopathic pulmonary fibrosis: physiologic tests, quantitative CT indexes, and CT visual scores as predictors of mortality. Radiology 2008;246:935-940.
16. Savarino E, Bazzica M, Zentilin P, Pohl D, Parodi A, Cittadini G, Negrini S, Indiveri F, Tutuian R, Savarino V, et al. Gastroesophageal reflux and pulmonary fibrosis in scleroderma: a study using pH-impedance monitoring. Am J Respir Crit Care Med 2009;179:408-413.