Luteolin inhibits fibrillary β-amyloid1-40 -induced inflammation in a human blood-brain barrier mode by suppressing the p38 MAPK-mediated NF-eκB signaling pathways

Molecules

Volumn 22, Issue 3, 2017, Pages

  Zhang, Jun Xia ^a   Xing, Jian Guo ^b   Wang, Lin Lin ^a   Jiang, Hai Lun ^a   Guo, Shui Long ^c,d   Liu, Rui ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b Xinjiang Institute of Materia Medica   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases   (China)

Author keywords

Alzheimer's disease; Amyloid peptides; Blood brain barrier; Cyclooxygenase 2; Cytokine; Fibrillar amyloid ; Luteolin; Mitogen activated protein kinases; Nuclear factor b; Peptides

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUTEOLIN; NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT;

APOPTOSIS; ASTROCYTE; BIOLOGICAL MODEL; BLOOD BRAIN BARRIER; BRAIN; CELL CULTURE; CELL SURVIVAL; COCULTURE; CYTOLOGY; DRUG EFFECTS; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; HUMAN; IMMUNOLOGY; METABOLISM; SIGNAL TRANSDUCTION; VASCULARIZATION;

AMYLOID BETA-PEPTIDES; APOPTOSIS; ASTROCYTES; BLOOD-BRAIN BARRIER; BRAIN; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOKINES; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; LUTEOLIN; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; NEUROPROTECTIVE AGENTS; NF-KAPPA B; PEPTIDE FRAGMENTS;

EID: 85014495048     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules22030334     Document Type: Article

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