Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

Acta Neuropathologica

Volumn 122, Issue 3, 2011, Pages 293-311

  Merlini, Mario ^a,b   Meyer, Eric P ^a   Ulmann Schuler, Alexandra ^a   Nitsch, Roger M ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

Author keywords

Alzheimer's disease; Astrocytes; Cerebral glucose metabolism; Congophilic amyloid angiopathy

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CARRIER PROTEIN; GLUCOSE; GLUCOSE TRANSPORTER 1; LACTATE TRANSPORTER; LACTIC ACID; UNCLASSIFIED DRUG;

AMYLOID PLAQUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BEHAVIOR DISORDER; BLOOD BRAIN BARRIER; BLOOD VESSEL OCCLUSION; BRAIN BLOOD VESSEL; BRAIN METABOLISM; CELL LOSS; CELL SWELLING; CEREBROVASCULAR DISEASE; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; FAMILIAL DISEASE; GLUCOSE TRANSPORT; HISTOPATHOLOGY; IN VIVO STUDY; METABOLIC DISORDER; MOUSE; NERVE CELL LESION; NERVE CELL STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; TRANSGENIC MOUSE; VASCULAR AMYLOIDOSIS; VASCULAR SMOOTH MUSCLE;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIGENS, CD31; ASTROCYTES; BASEMENT MEMBRANE; BLOOD-BRAIN BARRIER; BRAIN; CELL CULTURE TECHNIQUES; CEREBRAL AMYLOID ANGIOPATHY; CEREBRAL ARTERIES; CEREBROVASCULAR DISORDERS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DYSTROGLYCANS; ENDOTHELIUM; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; HEMORRHAGE; HUMANS; LACTASE; LAMININ; MICE; MICE, TRANSGENIC; MICRODIALYSIS; MICROSCOPY, ELECTRON, SCANNING; MONOCARBOXYLIC ACID TRANSPORTERS; MUSCLE, SMOOTH; PLAQUE, AMYLOID; SYMPORTERS;

EID: 80054711185     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0834-y     Document Type: Article

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