Luteolin inhibits viral-induced inflammatory response in RAW264.7 cells via suppression of STAT1/3 dependent NF-κB and activation of HO-1

Free Radical Biology and Medicine

Volumn 95, Issue , 2016, Pages 180-189

  Liu, Cheng Wei ^a   Lin, Hui Wen ^b,c   Yang, Deng Jye ^d   Chen, Shih Yin ^c   Tseng, Jung Kai ^b,c   Chang, Tien Jye ^e   Chang, Yuan Yen ^d  

^a MINGDAO UNIVERSITY   (Taiwan)

^b ASIA UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

HO 1; Luteolin; NF B; Nrf2; Pseudorabies virus (PRV); STAT1 3

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIVIRUS AGENT; CYCLOOXYGENASE 2; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTATE DEHYDROGENASE; LUTEOLIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTOPORPHYRIN TIN; STAT1 PROTEIN; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; HERBACEOUS AGENT; HMOX1 PROTEIN, MOUSE; MEMBRANE PROTEIN; NFE2L2 PROTEIN, MOUSE; STAT1 PROTEIN, MOUSE; STAT3 PROTEIN, MOUSE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CELL DEATH; CELL LINE RAW 264.7; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CYTOKINE PRODUCTION; DOSE RESPONSE; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; MTT ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PSEUDORABIES; PSEUDORABIES VIRUS; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION; VIRUS REPLICATION; ANIMAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; INFLAMMATION; MOUSE; PATHOGENICITY; PHOSPHORYLATION; RAW 264.7 CELL LINE; VIROLOGY;

ANIMALS; ANTIOXIDANTS; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; HERPESVIRUS 1, SUID; INFLAMMATION; LUTEOLIN; MEMBRANE PROTEINS; MICE; NF-E2-RELATED FACTOR 2; NF-KAPPA B; PHOSPHORYLATION; RAW 264.7 CELLS; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR;

EID: 84962045275     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2016.03.019     Document Type: Article

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