메뉴 건너뛰기




Volumn 1, Issue 8, 2015, Pages

Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEINS; LIVING SYSTEMS STUDIES; MEDICAL PROBLEMS; PROTEINS; TISSUE HOMEOSTASIS;

EID: 84976284861     PISSN: None     EISSN: 23752548     Source Type: Journal    
DOI: 10.1126/sciadv.1500472     Document Type: Article
Times cited : (116)

References (31)
  • 2
    • 0030669036 scopus 로고    scopus 로고
    • Thepathogenesisofsenileplaques
    • D.W.Dicksen,Thepathogenesisofsenileplaques.J.Neuropathol.Exp.Neurol.56,321–339(1997).
    • (1997) J.Neuropathol.Exp.Neurol. , vol.56 , pp. 321-339
    • Dicksen, D.W.1
  • 3
    • 0024231238 scopus 로고
    • Isolation and chemical characterization of Alzheimer’s disease paired helical filament cytoskeletons: Differentiation from amyloid plaque core protein
    • A. E. Roher, K. C. Palmer, V. Chau, M. J. Ball, Isolation and chemical characterization of Alzheimer’s disease paired helical filament cytoskeletons: Differentiation from amyloid plaque core protein. J. Cell Biol. 107, 2703–2716 (1988).
    • (1988) J. Cell Biol. , vol.107 , pp. 2703-2716
    • Roher, A.E.1    Palmer, K.C.2    Chau, V.3    Ball, M.J.4
  • 6
    • 84866664048 scopus 로고    scopus 로고
    • Neurovascular defects and faulty amyloid-b vascular clearance in Alzheimer’s disease
    • A. P. Sagare, R. D. Bell, B. V. Zlokovic, Neurovascular defects and faulty amyloid-b vascular clearance in Alzheimer’s disease. J. Alzheimers Dis. 33 (Suppl. 1), S87–S100 (2013).
    • (2013) J. Alzheimers Dis. , vol.33 , pp. S87-S100
    • Sagare, A.P.1    Bell, R.D.2    Zlokovic, B.V.3
  • 7
    • 84865592640 scopus 로고    scopus 로고
    • The pathophysiology and clinical presentation of cerebral amyloid angiopathy
    • E. Auriel, S. M. Greenberg, The pathophysiology and clinical presentation of cerebral amyloid angiopathy. Curr. Atheroscler. Rep. 14, 343–350 (2012).
    • (2012) Curr. Atheroscler. Rep. , vol.14 , pp. 343-350
    • Auriel, E.1    Greenberg, S.M.2
  • 9
    • 84889872057 scopus 로고    scopus 로고
    • Development, maintenance and disruption of the blood-brain barrier
    • B. Obermeier, R. Daneman, R. M. Ransohoff, Development, maintenance and disruption of the blood-brain barrier. Nat. Med. 19, 1584–1596 (2013).
    • (2013) Nat. Med. , vol.19 , pp. 1584-1596
    • Obermeier, B.1    Daneman, R.2    Ransohoff, R.M.3
  • 10
    • 78149456928 scopus 로고    scopus 로고
    • The mouse blood-brain barrier transcriptome: A new resource for understanding the development and function of brain endothelial cells
    • R. Daneman, L. Zhou, D. Agalliu, J. D. Cahoy, A. Kaushal, B. A. Barres, The mouse blood-brain barrier transcriptome: A new resource for understanding the development and function of brain endothelial cells. PLOS One 5, e13741 (2010).
    • (2010) PLOS One , vol.5 , pp. e13741
    • Daneman, R.1    Zhou, L.2    Agalliu, D.3    Cahoy, J.D.4    Kaushal, A.5    Barres, B.A.6
  • 11
    • 84875191169 scopus 로고    scopus 로고
    • Transporters of the blood–brain and blood–CSF interfaces in development and in the adult
    • N. R. Saunders, R. Daneman, K. M. Dziegielewska, S. A. Liddelow, Transporters of the blood–brain and blood–CSF interfaces in development and in the adult. Mol. Aspects Med. 34, 742–752 (2013).
    • (2013) Mol. Aspects Med. , vol.34 , pp. 742-752
    • Saunders, N.R.1    Daneman, R.2    Dziegielewska, K.M.3    Liddelow, S.A.4
  • 15
    • 80052330506 scopus 로고    scopus 로고
    • Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer’s disease
    • K. E. Biron, D. L. Dickstein, R. Gopaul, W. A. Jeffries, Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer’s disease. PLOS One 6, e23789 (2011).
    • (2011) PLOS One , vol.6
    • Biron, K.E.1    Dickstein, D.L.2    Gopaul, R.3    Jeffries, W.A.4
  • 17
    • 0030799122 scopus 로고    scopus 로고
    • Amyloid b-protein fibrillogenesis: Detection of a protofibrillar intermediate
    • D. M. Walsh, A. Lomakin, G. B. Benedek, M. M. Condron, D. B. Teplow, Amyloid b-protein fibrillogenesis: Detection of a protofibrillar intermediate. J. Biol. Chem. 272, 22364–22372 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 22364-22372
    • Walsh, D.M.1    Lomakin, A.2    Benedek, G.B.3    Condron, M.M.4    Teplow, D.B.5
  • 20
    • 0035863055 scopus 로고    scopus 로고
    • Age-dependent changes in brain, CSF, and plasma amyloid b protein in the Tg2576 transgenic mouse model of Alzheimer’s disease
    • T. Kawarabayashi, L. H. Younkin, T. C. Saido, M. Shoji, K. H. Ashe, S. G. Younkin, Age-dependent changes in brain, CSF, and plasma amyloid b protein in the Tg2576 transgenic mouse model of Alzheimer’s disease. J. Neurosci. 21, 372–381 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 372-381
    • Kawarabayashi, T.1    Younkin, L.H.2    Saido, T.C.3    Shoji, M.4    Ashe, K.H.5    Younkin, S.G.6
  • 21
    • 33947668266 scopus 로고    scopus 로고
    • T-maze alternation in the rodent
    • R. M. J. Deacon, J. N. P. Rawlins, T-maze alternation in the rodent. Nat. Protoc. 1, 7–12 (2006).
    • (2006) Nat. Protoc. , vol.1 , pp. 7-12
    • Deacon, R.M.J.1    Rawlins, J.N.P.2
  • 22
    • 38449122953 scopus 로고    scopus 로고
    • Distribution of amyloid precursor protein and amyloid-b immunoreactivity in DBA/2J glaucomatous mouse retinas
    • D. Goldblum, A. Kipfer-Kauer, G.-M. Sarra, S. Wolf, B. E. Frueh, Distribution of amyloid precursor protein and amyloid-b immunoreactivity in DBA/2J glaucomatous mouse retinas. Invest. Ophthalmol. Vis. Sci. 48, 5085–5090 (2007).
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 5085-5090
    • Goldblum, D.1    Kipfer-Kauer, A.2    Sarra, G.-M.3    Wolf, S.4    Frueh, B.E.5
  • 23
    • 84896726518 scopus 로고    scopus 로고
    • ApoE and Ab in Alzheimer’s disease: Accidental encounters or partners?
    • T. Kanekiyo, H. Xu, G. Bu, ApoE and Ab in Alzheimer’s disease: Accidental encounters or partners? Neuron 81, 740–754 (2014).
    • (2014) Neuron , vol.81 , pp. 740-754
    • Kanekiyo, T.1    Xu, H.2    Bu, G.3
  • 25
    • 84865526718 scopus 로고    scopus 로고
    • Lifelong management of amyloid-beta metabolism to prevent Alzheimer’s disease
    • S. Gandy, Lifelong management of amyloid-beta metabolism to prevent Alzheimer’s disease. N. Engl. J. Med. 367, 864–865 (2012).
    • (2012) N. Engl. J. Med. , vol.367 , pp. 864-865
    • Gandy, S.1
  • 28
    • 77954711307 scopus 로고    scopus 로고
    • Amyloid-b-induced occludin down-regulation and increased permeability in human brain endothelial cells is mediated by MAPK activation
    • L. M. Tai, K. A. Holloway, D. K. Male, A. J. Loughlin, I. A. Romero, Amyloid-b-induced occludin down-regulation and increased permeability in human brain endothelial cells is mediated by MAPK activation. J. Cell. Mol. Med. 14, 1101–1112 (2010).
    • (2010) J. Cell. Mol. Med. , vol.14 , pp. 1101-1112
    • Tai, L.M.1    Holloway, K.A.2    Male, D.K.3    Loughlin, A.J.4    Romero, I.A.5
  • 29
    • 80052266213 scopus 로고    scopus 로고
    • The amyloid cascade hypothesis for Alzheimer’s disease: An appraisal for the development of therapeutics
    • E. Karran, M. Mercken, B. De Strooper, The amyloid cascade hypothesis for Alzheimer’s disease: An appraisal for the development of therapeutics. Nat. Rev. Drug Discov. 10, 698–712 (2011).
    • (2011) Nat. Rev. Drug Discov. , vol.10 , pp. 698-712
    • Karran, E.1    Mercken, M.2    De Strooper, B.3
  • 30
    • 84898728701 scopus 로고    scopus 로고
    • Interpreting Alzheimer’s disease clinical trials in light of the effects on amyloid-b
    • J. H. Toyn, M. K. Ahlijanian, Interpreting Alzheimer’s disease clinical trials in light of the effects on amyloid-b. Alzheimers Res. Ther. 6, 14 (2014).
    • (2014) Alzheimers Res. Ther. , vol.6 , pp. 14
    • Toyn, J.H.1    Ahlijanian, M.K.2
  • 31
    • 84859434098 scopus 로고    scopus 로고
    • The levels of water-soluble and triton-soluble Ab are increased in Alzheimer’s disease brain
    • J. M. McDonald, N. J. Cairns, L. Taylor-Reinwald, D. Holtzman, D. M. Walsh, The levels of water-soluble and triton-soluble Ab are increased in Alzheimer’s disease brain. Brain Res. 1450, 138–147 (2012).
    • (2012) Brain Res. , vol.1450 , pp. 138-147
    • McDonald, J.M.1    Cairns, N.J.2    Taylor-Reinwald, L.3    Holtzman, D.4    Walsh, D.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.