Interleukin-1β induces cyclooxygenase-2 and prostaglandin E2 synthesis in human neuroblastoma cells: Involvement of p38 mitogen-activated protein kinase and nuclear factor-κB

Journal of Neurochemistry

Volumn 75, Issue 5, 2000, Pages 2020-2028

  Fiebich, B L ^a   Mueksch, B ^a   Boehringer, M ^a   Hull, M ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Alzheimer's disease; Cyclooxygenase; Nonsteroidal antiinflammatory drugs; Prostaglandin E2; Reactive oxygen intermediates; SK N SH neuroblastoma cells

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN E2; SCAVENGER; SYNAPTOPHYSIN; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)IMIDAZOLE; ANTIINFLAMMATORY AGENT; DEXAMETHASONE; DRUG DERIVATIVE; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; INTERLEUKIN 1; ISOENZYME; MEMBRANE PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NONSTEROID ANTIINFLAMMATORY AGENT; PROLINE; PROLINEDITHIOCARBAMATE; PROSTAGLANDIN SYNTHASE; PTGS2 PROTEIN, HUMAN; PYRIDINE DERIVATIVE; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMIC ACID; REACTIVE OXYGEN METABOLITE; THIOCARBAMIC ACID DERIVATIVE;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; INFLAMMATION; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; BIOSYNTHESIS; CELL CULTURE; DOSE RESPONSE; DRUG ANTAGONISM; GENETICS; METABOLISM; NEUROBLASTOMA; SIGNAL TRANSDUCTION;

ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYCLOOXYGENASE 2; DEXAMETHASONE; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; HUMANS; IMIDAZOLES; INTERLEUKIN-1; ISOENZYMES; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROBLASTOMA; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROLINE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRIDINES; PYRROLIDINES; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SIGNAL TRANSDUCTION; THIOCARBAMATES; TUMOR CELLS, CULTURED;

EID: 0033623371     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0752020.x     Document Type: Article

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