-
1
-
-
0021759003
-
Reinvestigation of the structure of oxidized and reduced flavin: carbon-13 and nitrogen-15 nuclear magnetic resonance study
-
Moonen, C.T., et al. Reinvestigation of the structure of oxidized and reduced flavin: carbon-13 and nitrogen-15 nuclear magnetic resonance study. Biochemistry 23 (1984), 4859–4867.
-
(1984)
Biochemistry
, vol.23
, pp. 4859-4867
-
-
Moonen, C.T.1
-
2
-
-
84903294538
-
Flavins
-
G.C.K. Roberts Springer
-
Gadda, G., Flavins. Roberts, G.C.K., (eds.) Encyclopedia of Biophysics, 2013, Springer, 771–775.
-
(2013)
Encyclopedia of Biophysics
, pp. 771-775
-
-
Gadda, G.1
-
3
-
-
84870925950
-
Flavoenzymes: versatile catalysts in biosynthetic pathways
-
Walsh, C.T., Wencewicz, T.A., Flavoenzymes: versatile catalysts in biosynthetic pathways. Nat. Prod. Rep. 30 (2013), 175–200.
-
(2013)
Nat. Prod. Rep.
, vol.30
, pp. 175-200
-
-
Walsh, C.T.1
Wencewicz, T.A.2
-
4
-
-
0005948684
-
Isolierung eines neuen gelben Ferments
-
Haas, E., Isolierung eines neuen gelben Ferments. Biochem. Z. 298 (1938), 378–390.
-
(1938)
Biochem. Z.
, vol.298
, pp. 378-390
-
-
Haas, E.1
-
5
-
-
0011365375
-
Action mechanism of the old yellow enzyme
-
Nakamura, T., et al. Action mechanism of the old yellow enzyme. J. Biochem. 57 (1965), 554–564.
-
(1965)
J. Biochem.
, vol.57
, pp. 554-564
-
-
Nakamura, T.1
-
6
-
-
0017831143
-
Chemical approaches to the study of enzymes catalyzing redox transformations
-
Walsh, C., Chemical approaches to the study of enzymes catalyzing redox transformations. Annu. Rev. Biochem. 47 (1978), 881–931.
-
(1978)
Annu. Rev. Biochem.
, vol.47
, pp. 881-931
-
-
Walsh, C.1
-
7
-
-
0036919327
-
Flavoenzymes that catalyse reactions with no net redox change
-
Bornemann, S., Flavoenzymes that catalyse reactions with no net redox change. Nat. Prod. Rep. 19 (2002), 761–772.
-
(2002)
Nat. Prod. Rep.
, vol.19
, pp. 761-772
-
-
Bornemann, S.1
-
8
-
-
0035987236
-
‘New uses for an old enzyme’ – the old yellow enzyme family of flavoenzymes
-
Williams, R.E., Bruce, N.C., ‘New uses for an old enzyme’ – the old yellow enzyme family of flavoenzymes. Microbiology 148 (2002), 1607–1614.
-
(2002)
Microbiology
, vol.148
, pp. 1607-1614
-
-
Williams, R.E.1
Bruce, N.C.2
-
9
-
-
16244383493
-
Predicting enzyme function from protein sequence
-
Minshull, J., et al. Predicting enzyme function from protein sequence. Curr. Opin. Chem. Biol. 9 (2005), 202–209.
-
(2005)
Curr. Opin. Chem. Biol.
, vol.9
, pp. 202-209
-
-
Minshull, J.1
-
10
-
-
79960570256
-
Flavogenomics–a genomic and structural view of flavin-dependent proteins
-
Macheroux, P., et al. Flavogenomics–a genomic and structural view of flavin-dependent proteins. FEBS J. 278 (2011), 2625–2634.
-
(2011)
FEBS J.
, vol.278
, pp. 2625-2634
-
-
Macheroux, P.1
-
12
-
-
84921436886
-
Flavins and flavoproteins: applications in medicine
-
Jortzik, E., et al. Flavins and flavoproteins: applications in medicine. Methods Mol. Biol. 1146 (2014), 113–157.
-
(2014)
Methods Mol. Biol.
, vol.1146
, pp. 113-157
-
-
Jortzik, E.1
-
13
-
-
0029038909
-
Introduction: flavoprotein structure and mechanism
-
Massey, V., Introduction: flavoprotein structure and mechanism. FASEB J. 9 (1995), 473–475.
-
(1995)
FASEB J.
, vol.9
, pp. 473-475
-
-
Massey, V.1
-
14
-
-
68149166459
-
Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain
-
Stuehr, D.J., et al. Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain. FEBS J. 276 (2009), 3959–3974.
-
(2009)
FEBS J.
, vol.276
, pp. 3959-3974
-
-
Stuehr, D.J.1
-
15
-
-
84962556232
-
Electron bifurcation
-
Peters, J.W., et al. Electron bifurcation. Curr. Opin. Chem. Biol. 31 (2016), 146–152.
-
(2016)
Curr. Opin. Chem. Biol.
, vol.31
, pp. 146-152
-
-
Peters, J.W.1
-
16
-
-
0034161331
-
Flavoenzymes: diverse catalysts with recurrent features
-
Fraaije, M., Mattevi, A., Flavoenzymes: diverse catalysts with recurrent features. Trends Biochem. Sci. 25 (2000), 126–132.
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 126-132
-
-
Fraaije, M.1
Mattevi, A.2
-
17
-
-
34047180214
-
New frontiers in structural flavoenzymology
-
De Colibus, L., Mattevi, A., New frontiers in structural flavoenzymology. Curr. Opin. Struc. Biol. 16 (2006), 722–728.
-
(2006)
Curr. Opin. Struc. Biol.
, vol.16
, pp. 722-728
-
-
De Colibus, L.1
Mattevi, A.2
-
18
-
-
0017879559
-
The structure of the flavoenzyme glutathione reductase
-
Schulz, G.E., et al. The structure of the flavoenzyme glutathione reductase. Nature 273 (1978), 120–124.
-
(1978)
Nature
, vol.273
, pp. 120-124
-
-
Schulz, G.E.1
-
19
-
-
0023041821
-
Prediction of the occurrence of the ADP-binding βαβ-fold in proteins, using an amino acid sequence fingerprint
-
Wierenga, R.K., et al. Prediction of the occurrence of the ADP-binding βαβ-fold in proteins, using an amino acid sequence fingerprint. J. Mol. Biol. 187 (1986), 101–107.
-
(1986)
J. Mol. Biol.
, vol.187
, pp. 101-107
-
-
Wierenga, R.K.1
-
20
-
-
84857807074
-
Blending Baeyer-Villiger monooxygenases: using a robust BVMO as a scaffold for creating chimeric enzymes with novel catalytic properties
-
van Beek, H.L., et al. Blending Baeyer-Villiger monooxygenases: using a robust BVMO as a scaffold for creating chimeric enzymes with novel catalytic properties. Chem. Commun. 48 (2012), 3288–3290.
-
(2012)
Chem. Commun.
, vol.48
, pp. 3288-3290
-
-
van Beek, H.L.1
-
21
-
-
84870713545
-
Noncanonical reactions of flavoenzymes
-
Sobrado, P., Noncanonical reactions of flavoenzymes. Int. J. Mol. Sci. 13 (2012), 16751–16768.
-
(2012)
Int. J. Mol. Sci.
, vol.13
, pp. 16751-16768
-
-
Sobrado, P.1
-
22
-
-
84954567664
-
Unusual flavoenzyme catalysis in marine bacteria
-
Teufel, R., et al. Unusual flavoenzyme catalysis in marine bacteria. Curr. Opin. Chem. Biol. 31 (2016), 31–39.
-
(2016)
Curr. Opin. Chem. Biol.
, vol.31
, pp. 31-39
-
-
Teufel, R.1
-
23
-
-
0014200553
-
Reduktive photoalkylierung des flavinkerns und flavinkatalysierte photodecarboxylierung von phenylacetat studien in der flavinreihe
-
Walker, W.H., et al. Reduktive photoalkylierung des flavinkerns und flavinkatalysierte photodecarboxylierung von phenylacetat studien in der flavinreihe. Helv. Chim. Acta 50 (1967), 2269–2279.
-
(1967)
Helv. Chim. Acta
, vol.50
, pp. 2269-2279
-
-
Walker, W.H.1
-
24
-
-
0015785951
-
Direct evidence for carbanions and covalent n5-flavin-carbanion adducts as catalytic intermediates in the oxidation of nitroethane by D-amino acid oxidase
-
Porter, D.J.T., et al. Direct evidence for carbanions and covalent n5-flavin-carbanion adducts as catalytic intermediates in the oxidation of nitroethane by D-amino acid oxidase. J. Biol. Chem. 248 (1973), 4400–4416.
-
(1973)
J. Biol. Chem.
, vol.248
, pp. 4400-4416
-
-
Porter, D.J.T.1
-
25
-
-
0015926842
-
Reaction of sulfite with isoalloxazines
-
Hevesi, L., Bruice, T.C., Reaction of sulfite with isoalloxazines. Biochemistry 12 (1973), 290–297.
-
(1973)
Biochemistry
, vol.12
, pp. 290-297
-
-
Hevesi, L.1
Bruice, T.C.2
-
26
-
-
0014669771
-
Studies on milk xanthine oxidase: some spectral and kinetic properties
-
Massey, V., et al. Studies on milk xanthine oxidase: some spectral and kinetic properties. J. Biol. Chem. 244 (1969), 1682–1691.
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 1682-1691
-
-
Massey, V.1
-
27
-
-
0032619605
-
UV-visible spectroscopy as a tool to study flavoproteins
-
Macheroux, P., UV-visible spectroscopy as a tool to study flavoproteins. Methods Mol. Biol. 131 (1999), 1–7.
-
(1999)
Methods Mol. Biol.
, vol.131
, pp. 1-7
-
-
Macheroux, P.1
-
28
-
-
0242696227
-
Plant adenosine 5′-phosphosulfate reductase is a novel iron-sulfur protein
-
Kopriva, S., et al. Plant adenosine 5′-phosphosulfate reductase is a novel iron-sulfur protein. J. Biol. Chem. 276 (2001), 42881–42886.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42881-42886
-
-
Kopriva, S.1
-
29
-
-
33644670560
-
Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5′-phosphosulfate reductase based on the structural characterization of different enzymatic states
-
Schiffer, A., et al. Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5′-phosphosulfate reductase based on the structural characterization of different enzymatic states. Biochemistry 45 (2006), 2960–2967.
-
(2006)
Biochemistry
, vol.45
, pp. 2960-2967
-
-
Schiffer, A.1
-
30
-
-
0022863121
-
Identifications of the true carbon-13 nuclear magnetic resonance spectrum of the stable intermediate II in bacterial luciferase
-
Vervoort, J., et al. Identifications of the true carbon-13 nuclear magnetic resonance spectrum of the stable intermediate II in bacterial luciferase. Biochemistry 25 (1986), 8062–8067.
-
(1986)
Biochemistry
, vol.25
, pp. 8062-8067
-
-
Vervoort, J.1
-
31
-
-
33646348711
-
To be or not to be an oxidase: challenging the oxygen reactivity of flavoenzymes
-
Mattevi, A., To be or not to be an oxidase: challenging the oxygen reactivity of flavoenzymes. Trends Biochem. Sci. 31 (2006), 276–283.
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 276-283
-
-
Mattevi, A.1
-
32
-
-
84865435786
-
The enigmatic reaction of flavins with oxygen
-
Chaiyen, P., et al. The enigmatic reaction of flavins with oxygen. Trends Biochem. Sci. 37 (2012), 373–380.
-
(2012)
Trends Biochem. Sci.
, vol.37
, pp. 373-380
-
-
Chaiyen, P.1
-
33
-
-
84957582098
-
Handbook of Flavoproteins
-
De Gruyter
-
Hille, R., et al. Handbook of Flavoproteins. 2012, De Gruyter.
-
(2012)
-
-
Hille, R.1
-
34
-
-
4344593011
-
Identification of inhibitors for UDP-galactopyranose mutase
-
Soltero-Higgin, M., Identification of inhibitors for UDP-galactopyranose mutase. J. Am. Chem. Soc. 34 (2004), 10532–11263.
-
(2004)
J. Am. Chem. Soc.
, vol.34
, pp. 10532-11263
-
-
Soltero-Higgin, M.1
-
35
-
-
84944743977
-
Virtual screening for UDP-galactopyranose mutase ligands identifies a new class of antimycobacterial agents
-
Kincaid, V.A., et al. Virtual screening for UDP-galactopyranose mutase ligands identifies a new class of antimycobacterial agents. ACS Chem. Biol. 10 (2015), 2209–2218.
-
(2015)
ACS Chem. Biol.
, vol.10
, pp. 2209-2218
-
-
Kincaid, V.A.1
-
36
-
-
70449674082
-
Structural basis of substrate binding to UDP-galactopyranose mutase: crystal structures in the reduced and oxidized state complexed with UDP-galactopyranose and UDP
-
Partha, S.K., et al. Structural basis of substrate binding to UDP-galactopyranose mutase: crystal structures in the reduced and oxidized state complexed with UDP-galactopyranose and UDP. J. Mol. Biol. 394 (2009), 864–877.
-
(2009)
J. Mol. Biol.
, vol.394
, pp. 864-877
-
-
Partha, S.K.1
-
37
-
-
84868674867
-
Reversible and efficient inhibition of UDP-galactopyranose mutase by electrophilic, constrained and unsaturated UDP-galactitol analogues
-
Ansiaux, C., et al. Reversible and efficient inhibition of UDP-galactopyranose mutase by electrophilic, constrained and unsaturated UDP-galactitol analogues. Chem. Eur. J. 18 (2012), 14860–14866.
-
(2012)
Chem. Eur. J.
, vol.18
, pp. 14860-14866
-
-
Ansiaux, C.1
-
38
-
-
84893714579
-
Structure, mechanism, and dynamics of UDP-galactopyranose mutase
-
Tanner, J.J., et al. Structure, mechanism, and dynamics of UDP-galactopyranose mutase. Arch. Biochem. Biophys. 544 (2014), 128–141.
-
(2014)
Arch. Biochem. Biophys.
, vol.544
, pp. 128-141
-
-
Tanner, J.J.1
-
39
-
-
0034833650
-
Mechanistic investigation of UDP-galactopyranose mutase from Escherichia coli using 2- and 3-fluorinated UDP-galactofuranose as probes
-
Zhang, Q., Liu, H.-W., Mechanistic investigation of UDP-galactopyranose mutase from Escherichia coli using 2- and 3-fluorinated UDP-galactofuranose as probes. J. Am. Chem. Soc. 123 (2001), 6756–6766.
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 6756-6766
-
-
Zhang, Q.1
Liu, H.-W.2
-
40
-
-
84858635325
-
Chemical mechanism of UDP-galactopyranose mutase from Trypanosoma cruzi: a potential drug target against Chagas’ disease
-
Oppenheimer, M., et al. Chemical mechanism of UDP-galactopyranose mutase from Trypanosoma cruzi: a potential drug target against Chagas’ disease. PLoS One, 7, 2012, e32918.
-
(2012)
PLoS One
, vol.7
, pp. e32918
-
-
Oppenheimer, M.1
-
41
-
-
84958730031
-
In crystallo capture of a covalent intermediate in the UDP-galactopyranose mutase reaction
-
Mehra-Chaudhary, R., In crystallo capture of a covalent intermediate in the UDP-galactopyranose mutase reaction. Biochemistry 55 (2016), 833–836.
-
(2016)
Biochemistry
, vol.55
, pp. 833-836
-
-
Mehra-Chaudhary, R.1
-
42
-
-
84883819129
-
Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity
-
Benjamin, D.I., et al. Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity. Proc. Natl. Acad. Sci. U. S. A. 110 (2013), 14912–14917.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 14912-14917
-
-
Benjamin, D.I.1
-
43
-
-
84947909618
-
Discovery of inhibitors for the ether lipid-generating enzyme AGPS as Anti-cancer agents
-
Piano, V., et al. Discovery of inhibitors for the ether lipid-generating enzyme AGPS as Anti-cancer agents. ACS Chem. Biol. 10 (2015), 2589–2597.
-
(2015)
ACS Chem. Biol.
, vol.10
, pp. 2589-2597
-
-
Piano, V.1
-
44
-
-
34249898356
-
The crucial step in ether phospholipid biosynthesis: structural basis of a noncanonical reaction associated with a peroxisomal disorder
-
Razeto, A., et al. The crucial step in ether phospholipid biosynthesis: structural basis of a noncanonical reaction associated with a peroxisomal disorder. Structure 15 (2007), 683–692.
-
(2007)
Structure
, vol.15
, pp. 683-692
-
-
Razeto, A.1
-
45
-
-
84869210790
-
Precursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysis
-
Nenci, S., et al. Precursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysis. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 18791–18796.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 18791-18796
-
-
Nenci, S.1
-
46
-
-
44549085227
-
The growing VAO flavoprotein family
-
Leferink, N.G., et al. The growing VAO flavoprotein family. Arch. Biochem. Biophys. 474 (2008), 292–301.
-
(2008)
Arch. Biochem. Biophys.
, vol.474
, pp. 292-301
-
-
Leferink, N.G.1
-
47
-
-
22844445708
-
Identification of a novel gene encoding a flavin-dependent tRNA:m5U methyltransferase in bacteria–evolutionary implications
-
Urbonavicius, J., et al. Identification of a novel gene encoding a flavin-dependent tRNA:m5U methyltransferase in bacteria–evolutionary implications. Nucleic Acids Res. 33 (2005), 3955–3964.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 3955-3964
-
-
Urbonavicius, J.1
-
48
-
-
0037025191
-
An alternative flavin-dependent mechanism for thymidylate synthesis
-
Myllykallio, H., et al. An alternative flavin-dependent mechanism for thymidylate synthesis. Science 297 (2002), 105–107.
-
(2002)
Science
, vol.297
, pp. 105-107
-
-
Myllykallio, H.1
-
49
-
-
0004107159
-
Metabolism of Nucleotides, Nucleosides and Nucleobases in Microorganisms
-
Academic Press
-
Munch-Petersen, A., Metabolism of Nucleotides, Nucleosides and Nucleobases in Microorganisms. 1983, Academic Press.
-
(1983)
-
-
Munch-Petersen, A.1
-
50
-
-
66349097175
-
Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase
-
Nishimasu, H., et al. Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 8180–8185.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 8180-8185
-
-
Nishimasu, H.1
-
51
-
-
84866860266
-
Folate binding site of flavin-dependent thymidylate synthase
-
Koehn, E.M., et al. Folate binding site of flavin-dependent thymidylate synthase. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 15722–15727.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 15722-15727
-
-
Koehn, E.M.1
-
52
-
-
80054714992
-
Insights into folate/FAD-dependent tRNA methyltransferase mechanism: role of two highly conserved cysteines in catalysis
-
Hamdane, D., et al. Insights into folate/FAD-dependent tRNA methyltransferase mechanism: role of two highly conserved cysteines in catalysis. J. Biol. Chem. 286 (2011), 36268–36280.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 36268-36280
-
-
Hamdane, D.1
-
53
-
-
84870665611
-
FAD/Folate-dependent tRNA methyltransferase: flavin as a new methyl-transfer agent
-
Hamdane, D., et al. FAD/Folate-dependent tRNA methyltransferase: flavin as a new methyl-transfer agent. J. Am. Chem. Soc. 134 (2012), 19739–19745.
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 19739-19745
-
-
Hamdane, D.1
-
54
-
-
84890544860
-
Activation of a unique flavin-dependent tRNA-methylating agent
-
Hamdane, D., et al. Activation of a unique flavin-dependent tRNA-methylating agent. Biochemistry 52 (2013), 8949–8956.
-
(2013)
Biochemistry
, vol.52
, pp. 8949-8956
-
-
Hamdane, D.1
-
55
-
-
84975060712
-
Deprotonations in the reaction of flavin-dependent thymidylate synthase
-
Stull, F.W., et al. Deprotonations in the reaction of flavin-dependent thymidylate synthase. Biochemistry 55 (2016), 3261–3269.
-
(2016)
Biochemistry
, vol.55
, pp. 3261-3269
-
-
Stull, F.W.1
-
56
-
-
84906222459
-
Detection of intermediates in the oxidative half-reaction of the FAD-dependent thymidylate synthase from Thermotoga maritima: carbon transfer without covalent pyrimidine activation
-
Conrad, J.A., et al. Detection of intermediates in the oxidative half-reaction of the FAD-dependent thymidylate synthase from Thermotoga maritima: carbon transfer without covalent pyrimidine activation. Biochemistry 53 (2014), 5199–5207.
-
(2014)
Biochemistry
, vol.53
, pp. 5199-5207
-
-
Conrad, J.A.1
-
57
-
-
84956629678
-
An unprecedented mechanism of nucleotide methylation in organisms containing thyX
-
Mishanina, T.V., et al. An unprecedented mechanism of nucleotide methylation in organisms containing thyX. Science 351 (2016), 507–510.
-
(2016)
Science
, vol.351
, pp. 507-510
-
-
Mishanina, T.V.1
-
58
-
-
84958983372
-
Biosynthesis of coenzyme Q in eukaryotes
-
Kawamukai, M., Biosynthesis of coenzyme Q in eukaryotes. Biosci. Biotechnol. Biochem. 80 (2015), 23–33.
-
(2015)
Biosci. Biotechnol. Biochem.
, vol.80
, pp. 23-33
-
-
Kawamukai, M.1
-
59
-
-
84933073520
-
New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition
-
Payne, K.A., et al. New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition. Nature 522 (2015), 497–501.
-
(2015)
Nature
, vol.522
, pp. 497-501
-
-
Payne, K.A.1
-
60
-
-
85015310184
-
-
Oxidative maturation and structural characterization of prenylated-FMN binding by UbiD, a decarboxylase involved in bacterial ubiquinone biosynthesis. Published online January 5.
-
Marshall, S.A. et al. (2017) Oxidative maturation and structural characterization of prenylated-FMN binding by UbiD, a decarboxylase involved in bacterial ubiquinone biosynthesis. J. Biol. Chem. Published online January 5, 2017. http://dx.doi.org/jbc.M116.762732.
-
(2017)
J. Biol. Chem.
-
-
Marshall, S.A.1
-
61
-
-
84933056649
-
UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis
-
White, M.D., et al. UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis. Nature 522 (2015), 502–506.
-
(2015)
Nature
, vol.522
, pp. 502-506
-
-
White, M.D.1
-
62
-
-
84944276688
-
Natural 1,3-dipolar cycloadditions
-
Baunach, M., Hertweck, C., Natural 1,3-dipolar cycloadditions. Angew. Chem. Int. Ed. Engl. 54 (2015), 12550–12552.
-
(2015)
Angew. Chem. Int. Ed. Engl.
, vol.54
, pp. 12550-12552
-
-
Baunach, M.1
Hertweck, C.2
-
63
-
-
84973154405
-
Sweating the assets of flavin cofactors: new insight of chemical versatility from knowledge of structure and mechanism
-
Leys, D., Scrutton, N.S., Sweating the assets of flavin cofactors: new insight of chemical versatility from knowledge of structure and mechanism. Curr. Opin. Struc. Biol. 41 (2016), 19–26.
-
(2016)
Curr. Opin. Struc. Biol.
, vol.41
, pp. 19-26
-
-
Leys, D.1
Scrutton, N.S.2
-
64
-
-
84893737023
-
Flavin dependent monooxygenases
-
Huijbers, M.M., et al. Flavin dependent monooxygenases. Arch. Biochem. Biophys. 544 (2014), 2–17.
-
(2014)
Arch. Biochem. Biophys.
, vol.544
, pp. 2-17
-
-
Huijbers, M.M.1
-
65
-
-
0037149649
-
Mutational analysis of the enterocin Favorskii biosynthetic rearrangement
-
Xiang, L.K., et al. Mutational analysis of the enterocin Favorskii biosynthetic rearrangement. Org. Lett. 4 (2002), 957–960.
-
(2002)
Org. Lett.
, vol.4
, pp. 957-960
-
-
Xiang, L.K.1
-
66
-
-
8144227951
-
EncM, a versatile enterocin biosynthetic enzyme involved in Favorskii oxidative rearrangement, aldol condensation, and heterocycle-forming reactions
-
Xiang, L., et al. EncM, a versatile enterocin biosynthetic enzyme involved in Favorskii oxidative rearrangement, aldol condensation, and heterocycle-forming reactions. Proc. Natl. Acad. Sci. U. S. A. 101 (2004), 15609–15614.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 15609-15614
-
-
Xiang, L.1
-
67
-
-
84888645117
-
Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement
-
Teufel, R., et al. Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement. Nature 503 (2013), 552–556.
-
(2013)
Nature
, vol.503
, pp. 552-556
-
-
Teufel, R.1
-
68
-
-
84935041606
-
Biochemical establishment and characterization of EncM's flavin-N5-oxide cofactor
-
Teufel, R., et al. Biochemical establishment and characterization of EncM's flavin-N5-oxide cofactor. J. Am. Chem. Soc. 137 (2015), 8078–8085.
-
(2015)
J. Am. Chem. Soc.
, vol.137
, pp. 8078-8085
-
-
Teufel, R.1
-
69
-
-
84971542390
-
Dibenzothiophene catabolism proceeds via a flavin-N5-oxide intermediate
-
Adak, S., Begley, T.P., Dibenzothiophene catabolism proceeds via a flavin-N5-oxide intermediate. J. Am. Chem. Soc. 138 (2016), 6424–6426.
-
(2016)
J. Am. Chem. Soc.
, vol.138
, pp. 6424-6426
-
-
Adak, S.1
Begley, T.P.2
-
70
-
-
84893737023
-
Flavin dependent monooxygenases
-
Huijbers, M.M., et al. Flavin dependent monooxygenases. Arch. Biochem. Biophys. 544 (2014), 2–17.
-
(2014)
Arch. Biochem. Biophys.
, vol.544
, pp. 2-17
-
-
Huijbers, M.M.1
-
71
-
-
66149173641
-
Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases
-
Edmondson, D.E., et al. Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases. Biochemistry 48 (2009), 4220–4230.
-
(2009)
Biochemistry
, vol.48
, pp. 4220-4230
-
-
Edmondson, D.E.1
-
72
-
-
0011669498
-
A new approach to the analysis of the interaction between monoamineoxidase and its substrates and inhibitors
-
Zeller, E.A., A new approach to the analysis of the interaction between monoamineoxidase and its substrates and inhibitors. Annu. N. Y. Acad. Sci. 107 (1963), 811–821.
-
(1963)
Annu. N. Y. Acad. Sci.
, vol.107
, pp. 811-821
-
-
Zeller, E.A.1
-
73
-
-
0017228490
-
Structure of flavin adducts with acetylenic substrates: chemistry of monoamine oxidase and lactate oxidase inhibition
-
Gärtner, B., et al. Structure of flavin adducts with acetylenic substrates: chemistry of monoamine oxidase and lactate oxidase inhibition. Eur. J. Biochem. 63 (1976), 211–221.
-
(1976)
Eur. J. Biochem.
, vol.63
, pp. 211-221
-
-
Gärtner, B.1
-
74
-
-
12144289182
-
Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class
-
Binda, C., et al. Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class. J. Med. Chem. 47 (2004), 1767–1774.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 1767-1774
-
-
Binda, C.1
-
75
-
-
12144287240
-
Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues
-
Hubálek, F., et al. Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues. J. Med. Chem. 47 (2004), 1760–1766.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 1760-1766
-
-
Hubálek, F.1
-
76
-
-
84961644830
-
LSD1 inhibitors: a patent review (2010–2015)
-
Stazi, G., et al. LSD1 inhibitors: a patent review (2010–2015). Expert. Opin. Ther. Pat. 26 (2016), 565–580.
-
(2016)
Expert. Opin. Ther. Pat.
, vol.26
, pp. 565-580
-
-
Stazi, G.1
-
77
-
-
84975687645
-
Irreversible LSD1 inhibitors: application of tranylcypromine and its derivatives in cancer treatment
-
Zheng, Y.C., et al. Irreversible LSD1 inhibitors: application of tranylcypromine and its derivatives in cancer treatment. Curr. Top. Med. Chem. 16 (2016), 2179–2188.
-
(2016)
Curr. Top. Med. Chem.
, vol.16
, pp. 2179-2188
-
-
Zheng, Y.C.1
-
78
-
-
77952355653
-
Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2
-
Binda, C., et al. Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2. J. Am. Chem. Soc. 132 (2010), 6827–6833.
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 6827-6833
-
-
Binda, C.1
-
79
-
-
84896135274
-
Flavin-dependent thymidylate synthase as a drug target for deadly microbes: mutational study and a strategy for inhibitor design
-
Mathews, I.I., Flavin-dependent thymidylate synthase as a drug target for deadly microbes: mutational study and a strategy for inhibitor design. J. Bioterror. Biodef., 12, 2013, 004.
-
(2013)
J. Bioterror. Biodef.
, vol.12
, pp. 004
-
-
Mathews, I.I.1
-
80
-
-
1942522084
-
Profiling enzyme activities in vivo using click chemistry methods
-
Speers, A.E., Cravatt, B.F., Profiling enzyme activities in vivo using click chemistry methods. Chem. Biol. 11 (2004), 535–546.
-
(2004)
Chem. Biol.
, vol.11
, pp. 535-546
-
-
Speers, A.E.1
Cravatt, B.F.2
-
81
-
-
84863672926
-
Activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of monoamine oxidase inhibitors
-
Krysiak, J.M., et al. Activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of monoamine oxidase inhibitors. Angew. Chem. Int. Ed. 51 (2012), 7035–7040.
-
(2012)
Angew. Chem. Int. Ed.
, vol.51
, pp. 7035-7040
-
-
Krysiak, J.M.1
|