New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition

Nature

Volumn 522, Issue 7557, 2015, Pages 497-501

  Payne, Karl A P ^a   White, Mark D ^a   Fisher, Karl ^a   Khara, Basile ^a   Bailey, Samuel S ^a   Parker, David ^b   Rattray, Nicholas J W ^a   Trivedi, Drupad K ^a   Goodacre, Royston ^a   Beveridge, Rebecca ^a   Barran, Perdita ^a   Rigby, Stephen E J ^a   Scrutton, Nigel S ^a   Hay, Sam ^a   Leys, David ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b Westhollow Technology Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BETA UNSATURATED FATTY ACID; BACTERIAL PROTEIN; CARBOXYLYASE; UBID PROTEIN; UBIQUINONE; UBIX PROTEIN; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID; 3-OCTAPRENYL-4-HYDROXYBENZOATE CARBOXY-LYASE; ALKENE; ESCHERICHIA COLI PROTEIN; LIGAND; PHENYLACRYLIC ACID DECARBOXYLASE; RIBOFLAVIN DERIVATIVE; UBIX PROTEIN, E COLI;

AROMATIC HYDROCARBON; BACTERIUM; BIOCHEMISTRY; BIODEGRADATION; CATALYSIS; CRYSTAL STRUCTURE; DECARBOXYLATION; ENZYME ACTIVITY; FUNGUS; GENE EXPRESSION; HYDROCARBON; MICROBIAL ACTIVITY;

1,3 DIPOLAR CYCLOADDITION; ARTICLE; BIOSYNTHESIS; CATALYSIS; COENZYME; COVALENT BOND; CRYSTAL STRUCTURE; CYCLOADDITION; DECARBOXYLATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME SUBSTRATE COMPLEX; FUNGAL GENOME; HYDROGEN BOND; ISOMERIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTON TRANSPORT; STRUCTURAL HOMOLOGY; SULFOXIDATION; ASPERGILLUS NIGER; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; ISOMERISM; METABOLISM; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS);

ALKENES; ASPERGILLUS NIGER; BIOCATALYSIS; CARBOXY-LYASES; CRYSTALLOGRAPHY, X-RAY; CYCLOADDITION REACTION; DECARBOXYLATION; ESCHERICHIA COLI PROTEINS; FLAVINS; ISOMERISM; LIGANDS; MODELS, MOLECULAR; UBIQUINONE;

EID: 84933073520     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14560     Document Type: Article

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