-
1
-
-
0015859467
-
Principles that govern the folding of protein chains
-
Anfinsen, C.B. Principles that govern the folding of protein chains. Science 1973, 181, 223-230.
-
(1973)
Science
, vol.181
, pp. 223-230
-
-
Anfinsen, C.B.1
-
2
-
-
0015875323
-
Structure-function relationships at the active site of nuclease-T'
-
Sanchez, G.R.; Chaiken, I.M.; Anfinsen, C.B. Structure-function relationships at the active site of nuclease-T'. J. Biol. Chem. 1973, 248, 3653-3659.
-
(1973)
J. Biol. Chem.
, vol.248
, pp. 3653-3659
-
-
Sanchez, G.R.1
Chaiken, I.M.2
Anfinsen, C.B.3
-
3
-
-
33748525221
-
Evolution of enzyme superfamilies
-
Glasner, M.E.; Gerlt, J.A.; Babbitt, P.C. Evolution of enzyme superfamilies. Curr. Opin. Chem. Biol. 2006, 10, 492-497.
-
(2006)
Curr. Opin. Chem. Biol.
, vol.10
, pp. 492-497
-
-
Glasner, M.E.1
Gerlt, J.A.2
Babbitt, P.C.3
-
4
-
-
36749091070
-
-
Oxford University Press: New York, NY, USA
-
Frey, P.A.; Hegeman, A.D. Enzymatic Reaction Mechanisms; Oxford University Press: New York, NY, USA, 2007; pp. 126-188.
-
(2007)
Enzymatic Reaction Mechanisms
, pp. 126-188
-
-
Frey, P.A.1
Hegeman, A.D.2
-
5
-
-
0016997305
-
Haemoglobin: Structure, function and synthesis
-
Perutz, M.F. Haemoglobin: Structure, function and synthesis. Br. Med. Bull. 1976, 32, 193-194.
-
(1976)
Br. Med. Bull.
, vol.32
, pp. 193-194
-
-
Perutz, M.F.1
-
7
-
-
0034161331
-
Flavoenzymes: Diverse catalysts with recurrent features
-
Fraaije, M.W.; Mattevi, A. Flavoenzymes: Diverse catalysts with recurrent features. Trends Biochem. Sci. 2000, 25, 126-132.
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 126-132
-
-
Fraaije, M.W.1
Mattevi, A.2
-
8
-
-
33745991798
-
Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts
-
Van Berkel, W.J.; Kamerbeek, N.M.; Fraaije, M.W. Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts. J. Biotechnol. 2006, 124, 670-689.
-
(2006)
J. Biotechnol.
, vol.124
, pp. 670-689
-
-
van Berkel, W.J.1
Kamerbeek, N.M.2
Fraaije, M.W.3
-
9
-
-
34447500880
-
The diverse roles of flavin coenzymes-nature's most versatile thespians
-
Mansoorabadi, S.O.; Thibodeaux, C.J.; Liu, H.W. The diverse roles of flavin coenzymes-nature's most versatile thespians. J. Org. Chem. 2007, 72, 6329-6342.
-
(2007)
J. Org. Chem.
, vol.72
, pp. 6329-6342
-
-
Mansoorabadi, S.O.1
Thibodeaux, C.J.2
Liu, H.W.3
-
10
-
-
0033851115
-
The chemical and biological versatility of riboflavin
-
Massey, V. The chemical and biological versatility of riboflavin. Biochem. Soc. Trans. 2000, 28, 283-296.
-
(2000)
Biochem. Soc. Trans.
, vol.28
, pp. 283-296
-
-
Massey, V.1
-
12
-
-
0028108347
-
Activation of molecular oxygen by flavins and flavoproteins
-
Massey, V. Activation of molecular oxygen by flavins and flavoproteins. J. Biol. Chem. 1994, 269, 22459-22462.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 22459-22462
-
-
Massey, V.1
-
13
-
-
1942485882
-
Carbanion versus hydride transfer mechanisms in flavoprotein-catalyzed dehydrogenations
-
Fitzpatrick, P.F. Carbanion versus hydride transfer mechanisms in flavoprotein-catalyzed dehydrogenations. Bioorg. Chem. 2004, 32, 125-139.
-
(2004)
Bioorg. Chem.
, vol.32
, pp. 125-139
-
-
Fitzpatrick, P.F.1
-
14
-
-
0344583742
-
Analysis of the role of the active site residue Arg98 in the flavoprotein tryptophan 2-monooxygenase, a member of the L-amino oxidase family
-
Sobrado, P.; Fitzpatrick, P.F. Analysis of the role of the active site residue Arg98 in the flavoprotein tryptophan 2-monooxygenase, a member of the L-amino oxidase family. Biochemistry 2003, 42, 13826-13832.
-
(2003)
Biochemistry
, vol.42
, pp. 13826-13832
-
-
Sobrado, P.1
Fitzpatrick, P.F.2
-
15
-
-
77955251194
-
Aspergillus fumigatus SidA is a highly specific ornithine hydroxylase with bound flavin cofactor
-
Chocklett, S.W.; Sobrado, P. Aspergillus fumigatus SidA is a highly specific ornithine hydroxylase with bound flavin cofactor. Biochemistry 2010, 49, 6777-6783.
-
(2010)
Biochemistry
, vol.49
, pp. 6777-6783
-
-
Chocklett, S.W.1
Sobrado, P.2
-
16
-
-
0036919327
-
Flavoenzymes that catalyse reactions with no net redox change
-
Bornemann, S. Flavoenzymes that catalyse reactions with no net redox change. Nat. Prod. Rep. 2002, 19, 761-772.
-
(2002)
Nat. Prod. Rep.
, vol.19
, pp. 761-772
-
-
Bornemann, S.1
-
17
-
-
0032944057
-
A unique reaction in a common pathway: Mechanism and function of chorismate synthase in the shikimate pathway
-
Macheroux, P.; Schmid, J.; Amrhein, N.; Schaller, A. A unique reaction in a common pathway: Mechanism and function of chorismate synthase in the shikimate pathway. Planta 1999, 207, 325-334.
-
(1999)
Planta
, vol.207
, pp. 325-334
-
-
McHeroux, P.1
Schmid, J.2
Amrhein, N.3
Schaller, A.4
-
18
-
-
0030034327
-
Escherichia coli chorismate synthase
-
Bornemann, S.; Lowe, D.J.; Thorneley, R.N. Escherichia coli chorismate synthase. Biochem. Soc. Trans. 1996, 24, 84-88.
-
(1996)
Biochem. Soc. Trans.
, vol.24
, pp. 84-88
-
-
Bornemann, S.1
Lowe, D.J.2
Thorneley, R.N.3
-
19
-
-
0014668342
-
Stereochemistry of chorismic acid biosynthesis
-
Hill, R.K.; Newkome, G.R. Stereochemistry of chorismic acid biosynthesis. J. Am. Chem. Soc. 1969, 91, 5893-5894.
-
(1969)
J. Am. Chem. Soc.
, vol.91
, pp. 5893-5894
-
-
Hill, R.K.1
Newkome, G.R.2
-
20
-
-
0015500357
-
Stereochemistry of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase reaction and the chorismate synthetase reaction
-
Floss, H.G.; Onderka, D.K.; Carroll, M. Stereochemistry of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase reaction and the chorismate synthetase reaction. J. Biol. Chem. 1972, 247, 736-744.
-
(1972)
J. Biol. Chem.
, vol.247
, pp. 736-744
-
-
Floss, H.G.1
Onderka, D.K.2
Carroll, M.3
-
21
-
-
0014668324
-
Steric course of the chorismate synthetase reaction and the 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthetase reaction
-
Onderka, D.K.; Floss, H.G. Steric course of the chorismate synthetase reaction and the 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthetase reaction. J. Am. Chem. Soc. 1969, 91, 5894-5896.
-
(1969)
J. Am. Chem. Soc.
, vol.91
, pp. 5894-5896
-
-
Onderka, D.K.1
Floss, H.G.2
-
22
-
-
0017803293
-
Purification and properties of chorismate synthase from
-
Hasan, N.; Nester, E.W. Purification and properties of chorismate synthase from Bacillus subtilis. J. Biol. Chem. 1978, 253, 4993-4998.
-
(1978)
Bacillus subtilis. J. Biol. Chem.
, vol.253
, pp. 4993-4998
-
-
Hasan, N.1
Nester, E.W.2
-
23
-
-
0029088830
-
Escherichia coli chorismate synthase catalyzes the conversion of (6S)-6-fluoro-5-enolpyruvylshikimate-3-phosphate to 6-fluorochorismate. Implications for the enzyme mechanism and the antimicrobial action of (6S)-6-fluoroshikimate
-
Bornemann, S.; Ramjee, M.K.; Balasubramanian, S.; Abell, C.; Coggins, J.R.; Lowe, D.J.; Thorneley, R.N. Escherichia coli chorismate synthase catalyzes the conversion of (6S)-6-fluoro-5-enolpyruvylshikimate-3-phosphate to 6-fluorochorismate. Implications for the enzyme mechanism and the antimicrobial action of (6S)-6-fluoroshikimate. J. Biol. Chem. 1995, 270, 22811-22815.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 22811-22815
-
-
Bornemann, S.1
Ramjee, M.K.2
Balasubramanian, S.3
Abell, C.4
Coggins, J.R.5
Lowe, D.J.6
Thorneley, R.N.7
-
24
-
-
0005948379
-
Stereochemistry of 1,4-conjugate elimination reactions
-
Hill, R.K.; Bock, M.G. Stereochemistry of 1,4-conjugate elimination reactions. J. Am. Chem. Soc. 1978, 100, 637-639.
-
(1978)
J. Am. Chem. Soc.
, vol.100
, pp. 637-639
-
-
Hill, R.K.1
Bock, M.G.2
-
25
-
-
0029743937
-
The transient kinetics of Escherichia coli chorismate synthase: Substrate consumption, product formation, phosphate dissociation, and characterization of a flavin intermediate
-
Bornemann, S.; Lowe, D.J.; Thorneley, R.N. The transient kinetics of Escherichia coli chorismate synthase: Substrate consumption, product formation, phosphate dissociation, and characterization of a flavin intermediate. Biochemistry 1996, 35, 9907-9916.
-
(1996)
Biochemistry
, vol.35
, pp. 9907-9916
-
-
Bornemann, S.1
Lowe, D.J.2
Thorneley, R.N.3
-
26
-
-
1542304728
-
Mechanism of chorismate synthase. Role of the two invariant histidine residues in the active site
-
Kitzing, K.; Auweter, S.; Amrhein, N.; Macheroux, P. Mechanism of chorismate synthase. Role of the two invariant histidine residues in the active site. J. Biol. Chem. 2004, 279, 9451-9461.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 9451-9461
-
-
Kitzing, K.1
Auweter, S.2
Amrhein, N.3
McHeroux, P.4
-
27
-
-
33947681716
-
Mutagenic analysis of an invariant aspartate residue in chorismate synthase supports its role as an active site base
-
Rauch, G.; Ehammer, H.; Bornemann, S.; Macheroux, P. Mutagenic analysis of an invariant aspartate residue in chorismate synthase supports its role as an active site base. Biochemistry 2007, 46, 3768-3774.
-
(2007)
Biochemistry
, vol.46
, pp. 3768-3774
-
-
Rauch, G.1
Ehammer, H.2
Bornemann, S.3
McHeroux, P.4
-
28
-
-
0344868502
-
The structure of chorismate synthase reveals a novel flavin binding site fundamental to a unique chemical reaction
-
Maclean, J.; Ali, S. The structure of chorismate synthase reveals a novel flavin binding site fundamental to a unique chemical reaction. Structure 2003, 11, 1499-1511.
-
(2003)
Structure
, vol.11
, pp. 1499-1511
-
-
McLean, J.1
Ali, S.2
-
29
-
-
0029967883
-
Studies with flavin analogs provide evidence that a protonated reduced FMN is the substrate-induced transient intermediate in the reaction of Escherichia coli chorismate synthase
-
Macheroux, P.; Bornemann, S.; Ghisla, S.; Thorneley, R.N. Studies with flavin analogs provide evidence that a protonated reduced FMN is the substrate-induced transient intermediate in the reaction of Escherichia coli chorismate synthase. J. Biol. Chem. 1996, 271, 25850-25858.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 25850-25858
-
-
McHeroux, P.1
Bornemann, S.2
Ghisla, S.3
Thorneley, R.N.4
-
30
-
-
0025134148
-
Chorismate synthase. Pre-steady-state kinetics of phosphate release from 5-enolpyruvylshikimate 3-phosphate
-
Hawkes, T.R.; Lewis, T.; Coggins, J.R.; Mousdale, D.M.; Lowe, D.J.; Thorneley, R.N. Chorismate synthase. Pre-steady-state kinetics of phosphate release from 5-enolpyruvylshikimate 3-phosphate. Biochem. J. 1990, 265, 899-902.
-
(1990)
Biochem. J.
, vol.265
, pp. 899-902
-
-
Hawkes, T.R.1
Lewis, T.2
Coggins, J.R.3
Mousdale, D.M.4
Lowe, D.J.5
Thorneley, R.N.6
-
31
-
-
0034680841
-
Studies with substrate and cofactor analogues provide evidence for a radical mechanism in the chorismate synthase reaction
-
Osborne, A.; Thorneley, R.N.; Abell, C.; Bornemann, S. Studies with substrate and cofactor analogues provide evidence for a radical mechanism in the chorismate synthase reaction. J. Biol. Chem. 2000, 275, 35825-35830.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35825-35830
-
-
Osborne, A.1
Thorneley, R.N.2
Abell, C.3
Bornemann, S.4
-
32
-
-
0035947670
-
Chorismate synthase from the hyperthermophile Thermotoga maritima combines thermostability and increased rigidity with catalytic and spectral properties similar to mesophilic counterparts
-
Fitzpatrick, T.B.; Killer, P.; Thomas, R.M.; Jelesarov, I.; Amrhein, N.; Macheroux, P. Chorismate synthase from the hyperthermophile Thermotoga maritima combines thermostability and increased rigidity with catalytic and spectral properties similar to mesophilic counterparts. J. Biol. Chem. 2001, 276, 18052-18059.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18052-18059
-
-
Fitzpatrick, T.B.1
Killer, P.2
Thomas, R.M.3
Jelesarov, I.4
Amrhein, N.5
McHeroux, P.6
-
33
-
-
0030065765
-
Binding of the oxidized, reduced, and radical flavin species to chorismate synthase. An investigation by spectrophotometry, fluorimetry, and electron paramagnetic resonance and electron nuclear double resonance spectroscopy
-
Macheroux, P.; Petersen, J.; Bornemann, S.; Lowe, D.J.; Thorneley, R.N. Binding of the oxidized, reduced, and radical flavin species to chorismate synthase. An investigation by spectrophotometry, fluorimetry, and electron paramagnetic resonance and electron nuclear double resonance spectroscopy. Biochemistry 1996, 35, 1643-1652.
-
(1996)
Biochemistry
, vol.35
, pp. 1643-1652
-
-
McHeroux, P.1
Petersen, J.2
Bornemann, S.3
Lowe, D.J.4
Thorneley, R.N.5
-
34
-
-
0014514120
-
One-electron reactions in biochemical systems as studied by pulse radiolysis. II. Riboflavin
-
Land, E.J.; Swallow, A.J. One-electron reactions in biochemical systems as studied by pulse radiolysis. II. Riboflavin. Biochemistry 1969, 8, 2117-2125.
-
(1969)
Biochemistry
, vol.8
, pp. 2117-2125
-
-
Land, E.J.1
Swallow, A.J.2
-
35
-
-
40749096084
-
Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity
-
Rauch, G.; Ehammer, H.; Bornemann, S.; Macheroux, P. Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity. FEBS J. 2008, 275, 1464-1473.
-
(2008)
FEBS J.
, vol.275
, pp. 1464-1473
-
-
Rauch, G.1
Ehammer, H.2
Bornemann, S.3
McHeroux, P.4
-
36
-
-
0037394552
-
Diversity of the biosynthesis of the isoprene units
-
Kuzuyama, T.; Seto, H. Diversity of the biosynthesis of the isoprene units. Nat. Prod. Rep. 2003, 20, 171-183.
-
(2003)
Nat. Prod. Rep.
, vol.20
, pp. 171-183
-
-
Kuzuyama, T.1
Seto, H.2
-
37
-
-
33748360507
-
Escherichia coli type I isopentenyl diphosphate isomerase: Structural and catalytic roles for divalent metals
-
Lee, S.; Poulter, C.D. Escherichia coli type I isopentenyl diphosphate isomerase: Structural and catalytic roles for divalent metals. J. Am. Chem. Soc. 2006, 128, 11545-11550.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 11545-11550
-
-
Lee, S.1
Poulter, C.D.2
-
38
-
-
0041866630
-
Zinc is an essential cofactor for type I isopentenyl diphosphate:Dimethylallyl diphosphate isomerase
-
Carrigan, C.N.; Poulter, C.D. Zinc is an essential cofactor for type I isopentenyl diphosphate:dimethylallyl diphosphate isomerase. J. Am. Chem. Soc. 2003, 125, 9008-9009.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 9008-9009
-
-
Carrigan, C.N.1
Poulter, C.D.2
-
39
-
-
0038485617
-
Catalytic mechanism of Escherichia coli isopentenyl diphosphate isomerase involves Cys-67, Glu-116, and Tyr-104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitors
-
Wouters, J.; Oudjama, Y.; Barkley, S.J.; Tricot, C.; Stalon, V.; Droogmans, L.; Poulter, C.D. Catalytic mechanism of Escherichia coli isopentenyl diphosphate isomerase involves Cys-67, Glu-116, and Tyr-104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitors. J. Biol. Chem. 2003, 278, 11903-11908.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11903-11908
-
-
Wouters, J.1
Oudjama, Y.2
Barkley, S.J.3
Tricot, C.4
Stalon, V.5
Droogmans, L.6
Poulter, C.D.7
-
40
-
-
0346458808
-
Crystal structure of the C67A mutant of isopentenyl diphosphate isomerase complexed with a mechanism-based irreversible inhibitor
-
Wouters, J.; Oudjama, Y.; Stalon, V.; Droogmans, L.; Poulter, C.D. Crystal structure of the C67A mutant of isopentenyl diphosphate isomerase complexed with a mechanism-based irreversible inhibitor. Proteins 2004, 54, 216-221.
-
(2004)
Proteins
, vol.54
, pp. 216-221
-
-
Wouters, J.1
Oudjama, Y.2
Stalon, V.3
Droogmans, L.4
Poulter, C.D.5
-
41
-
-
34447555863
-
Characterization and mechanistic studies of type II isopentenyl diphosphate:Dimethylallyl diphosphate isomerase from Staphylococcus aureus
-
Kittleman, W.; Thibodeaux, C.J.; Liu, Y.N.; Zhang, H.; Liu, H.W. Characterization and mechanistic studies of type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Staphylococcus aureus. Biochemistry 2007, 46, 8401-8413.
-
(2007)
Biochemistry
, vol.46
, pp. 8401-8413
-
-
Kittleman, W.1
Thibodeaux, C.J.2
Liu, Y.N.3
Zhang, H.4
Liu, H.W.5
-
42
-
-
34347243472
-
Type-2 isopentenyl diphosphate isomerase. Mechanistic studies with cyclopropyl and epoxy analogues
-
Johnston, J.B.; Walker, J.R.; Rothman, S.C.; Poulter, C.D. Type-2 isopentenyl diphosphate isomerase. Mechanistic studies with cyclopropyl and epoxy analogues. J. Am. Chem. Soc. 2007, 129, 7740-7741.
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 7740-7741
-
-
Johnston, J.B.1
Walker, J.R.2
Rothman, S.C.3
Poulter, C.D.4
-
43
-
-
41849091915
-
Type II isopentenyl diphosphate isomerase: Irreversible inactivation by covalent modification of flavin
-
Rothman, S.C.; Johnston, J.B.; Lee, S.; Walker, J.R.; Poulter, C.D. Type II isopentenyl diphosphate isomerase: Irreversible inactivation by covalent modification of flavin. J. Am. Chem. Soc.2008, 130, 4906-4913.
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 4906-4913
-
-
Rothman, S.C.1
Johnston, J.B.2
Lee, S.3
Walker, J.R.4
Poulter, C.D.5
-
44
-
-
39749154761
-
Evidence for the involvement of acid/base chemistry in the reaction catalyzed by the type II isopentenyl diphosphate/dimethylallyl diphosphate isomerase from Staphylococcus aureus
-
Thibodeaux, C.J.; Mansoorabadi, S.O.; Kittleman, W.; Chang, W.C.; Liu, H.W. Evidence for the involvement of acid/base chemistry in the reaction catalyzed by the type II isopentenyl diphosphate/dimethylallyl diphosphate isomerase from Staphylococcus aureus. Biochemistry 2008, 47, 2547-2558.
-
(2008)
Biochemistry
, vol.47
, pp. 2547-2558
-
-
Thibodeaux, C.J.1
Mansoorabadi, S.O.2
Kittleman, W.3
Chang, W.C.4
Liu, H.W.5
-
45
-
-
29244458419
-
Reduced flavin: NMR investigation of N5-H exchange mechanism, estimation of ionisation constants and assessment of properties as biological catalyst
-
Macheroux, P.; Ghisla, S.; Sanner, C.; Ruterjans, H.; Muller, F. Reduced flavin: NMR investigation of N5-H exchange mechanism, estimation of ionisation constants and assessment of properties as biological catalyst. BMC Biochemistry 2005, 6, 26.
-
(2005)
BMC Biochemistry
, vol.6
, pp. 26
-
-
McHeroux, P.1
Ghisla, S.2
Sanner, C.3
Ruterjans, H.4
Muller, F.5
-
46
-
-
66149104732
-
New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase
-
Unno, H.; Yamashita, S.; Ikeda, Y.; Sekiguchi, S.Y.; Yoshida, N.; Yoshimura, T.; Kusunoki, M.; Nakayama, T.; Nishino, T.; Hemmi, H. New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. J. Biol. Chem. 2009, 284, 9160-9167.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 9160-9167
-
-
Unno, H.1
Yamashita, S.2
Ikeda, Y.3
Sekiguchi, S.Y.4
Yoshida, N.5
Yoshimura, T.6
Kusunoki, M.7
Nakayama, T.8
Nishino, T.9
Hemmi, H.10
-
47
-
-
50849124455
-
Crystal structure of type 2 isopentenyl diphosphate isomerase from Thermus thermophilus in complex with inorganic pyrophosphate
-
De Ruyck, J.; Pouyez, J.; Rothman, S.C.; Poulter, D.; Wouters, J. Crystal structure of type 2 isopentenyl diphosphate isomerase from Thermus thermophilus in complex with inorganic pyrophosphate. Biochemistry 2008, 47, 9051-9053.
-
(2008)
Biochemistry
, vol.47
, pp. 9051-9053
-
-
de Ruyck, J.1
Pouyez, J.2
Rothman, S.C.3
Poulter, D.4
Wouters, J.5
-
48
-
-
77955806280
-
Linear free energy relationships demonstrate a catalytic role for the flavin mononucleotide coenzyme of the type II isopentenyl diphosphate:Dimethylallyl diphosphate isomerase
-
Thibodeaux, C.J.; Chang, W.C.; Liu, H.W. Linear free energy relationships demonstrate a catalytic role for the flavin mononucleotide coenzyme of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase. J. Am. Chem. Soc. 2010, 132, 9994-9996.
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 9994-9996
-
-
Thibodeaux, C.J.1
Chang, W.C.2
Liu, H.W.3
-
49
-
-
84155174687
-
Stereochemical studies of the type II isopentenyl diphosphate-dimethylallyl diphosphate isomerase implicate the FMN coenzyme in substrate protonation
-
Calveras, J.; Thibodeaux, C.J.; Mansoorabadi, S.O.; Liu, H.W. Stereochemical studies of the type II isopentenyl diphosphate-dimethylallyl diphosphate isomerase implicate the FMN coenzyme in substrate protonation. Chembiochem 2012, 13, 42-46.
-
(2012)
Chembiochem
, vol.13
, pp. 42-46
-
-
Calveras, J.1
Thibodeaux, C.J.2
Mansoorabadi, S.O.3
Liu, H.W.4
-
50
-
-
20444477920
-
Eukaryotic UDP-galactopyranose mutase (GLF gene) in microbial and metazoal pathogens
-
Beverley, S.M.; Owens, K.L.; Showalter, M.; Griffith, C.L.; Doering, T.L.; Jones, V.C.; McNeil, M.R. Eukaryotic UDP-galactopyranose mutase (GLF gene) in microbial and metazoal pathogens. Eukaryotic Cell 2005, 4, 1147-1154.
-
(2005)
Eukaryotic Cell
, vol.4
, pp. 1147-1154
-
-
Beverley, S.M.1
Owens, K.L.2
Showalter, M.3
Griffith, C.L.4
Doering, T.L.5
Jones, V.C.6
McNeil, M.R.7
-
51
-
-
0037301077
-
Galactofuranose metabolism: A potential target for antimicrobial chemotherapy
-
Pedersen, L.L.; Turco, S.J. Galactofuranose metabolism: A potential target for antimicrobial chemotherapy. Cell Mol. Life Sci. 2003, 60, 259-266.
-
(2003)
Cell Mol. Life Sci.
, vol.60
, pp. 259-266
-
-
Pedersen, L.L.1
Turco, S.J.2
-
52
-
-
0034971311
-
Cell wall core galactofuran synthesis is essential for growth of mycobacteria
-
Pan, F.; Jackson, M.; Ma, Y.; McNeil, M. Cell wall core galactofuran synthesis is essential for growth of mycobacteria. J. Bacteriol. 2001, 183, 3991-3998.
-
(2001)
J. Bacteriol.
, vol.183
, pp. 3991-3998
-
-
Pan, F.1
Jackson, M.2
Ma, Y.3
McNeil, M.4
-
53
-
-
48949102782
-
Contribution of galactofuranose to the virulence of the opportunistic pathogen Aspergillus fumigatus
-
Schmalhorst, P.S.; Krappmann, S.; Vervecken, W.; Rohde, M.; Muller, M.; Braus, G.H.; Contreras, R.; Braun, A.; Bakker, H.; Routier, F.H. Contribution of galactofuranose to the virulence of the opportunistic pathogen Aspergillus fumigatus. Eukaryotic Cell 2008, 7, 1268-1277.
-
(2008)
Eukaryotic Cell
, vol.7
, pp. 1268-1277
-
-
Schmalhorst, P.S.1
Krappmann, S.2
Vervecken, W.3
Rohde, M.4
Muller, M.5
Braus, G.H.6
Contreras, R.7
Braun, A.8
Bakker, H.9
Routier, F.H.10
-
54
-
-
34249852365
-
Targeted gene deletion of Leishmania major UDP-galactopyranose mutase leads to attenuated virulence
-
Kleczka, B.; Lamerz, A.C.; van Zandbergen, G.; Wenzel, A.; Gerardy-Schahn, R.; Wiese, M.; Routier, F.H. Targeted gene deletion of Leishmania major UDP-galactopyranose mutase leads to attenuated virulence. J. Biol. Chem. 2007, 282, 10498-10505.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 10498-10505
-
-
Kleczka, B.1
Lamerz, A.C.2
van Zandbergen, G.3
Wenzel, A.4
Gerardy-Schahn, R.5
Wiese, M.6
Routier, F.H.7
-
55
-
-
84858653974
-
Biosynthesis of galactofuranose in kinetoplastids: Novel therapeutic targets for treating leishmaniasis and chagas' disease
-
Oppenheimer, M.; Valenciano, A.L.; Sobrado, P. Biosynthesis of galactofuranose in kinetoplastids: Novel therapeutic targets for treating leishmaniasis and chagas' disease. Enzyme Res. 2011, 2011, 415976.
-
(2011)
Enzyme Res.
, vol.2011
, pp. 415976
-
-
Oppenheimer, M.1
Valenciano, A.L.2
Sobrado, P.3
-
56
-
-
0031590269
-
The surface glycoconjugates of trypanosomatid parasites
-
Ferguson, M.A. The surface glycoconjugates of trypanosomatid parasites. Philos. Trans. Roy. Soc. London 1997, 352, 1295-1302.
-
(1997)
Philos. Trans. Roy. Soc. London
, vol.352
, pp. 1295-1302
-
-
Ferguson, M.A.1
-
57
-
-
84870715804
-
Functional Expression and Purification of UDP-Galactopyranose Mutase from Trypanosoma cruzi
-
In Frago, S., Gomez-Moreno, C., Medina, M., Eds.; Prensas Universitarias de Zaragoza: Zarazoza, Spain
-
Sobrado, P. Functional Expression and Purification of UDP-Galactopyranose Mutase from Trypanosoma cruzi. In Flavins and Flavoproteins; Frago, S., Gomez-Moreno, C., Medina, M., Eds.; Prensas Universitarias de Zaragoza: Zarazoza, Spain, 2008; pp. 509-513.
-
(2008)
Flavins and Flavoproteins
, pp. 509-513
-
-
Sobrado, P.1
-
58
-
-
84858591359
-
Crystal structures and small-angle X-ray scattering analysis of UDP-galactopyranose mutase from the pathogenic fungus
-
Dhatwalia, R.; Singh, H.; Oppenheimer, M.; Karr, D.B.; Nix, J.C.; Sobrado, P.; Tanner, J.J. Crystal structures and small-angle X-ray scattering analysis of UDP-galactopyranose mutase from the pathogenic fungus Aspergillus fumigatus. J. Biol. Chem. 2012, 287, 9041-9051.
-
(2012)
Aspergillus fumigatus. J. Biol. Chem.
, vol.287
, pp. 9041-9051
-
-
Dhatwalia, R.1
Singh, H.2
Oppenheimer, M.3
Karr, D.B.4
Nix, J.C.5
Sobrado, P.6
Tanner, J.J.7
-
59
-
-
84862529810
-
Crystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme Activation
-
Dhatwalia, R.; Singh, H.; Oppenheimer, M.; Sobrado, P.; Tanner, J.J. Crystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme Activation. Biochemistry 2012, 51, 4968-4979.
-
(2012)
Biochemistry
, vol.51
, pp. 4968-4979
-
-
Dhatwalia, R.1
Singh, H.2
Oppenheimer, M.3
Sobrado, P.4
Tanner, J.J.5
-
60
-
-
17444429638
-
Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state
-
Beis, K.; Srikannathasan, V.; Liu, H.; Fullerton, S.W.; Bamford, V.A.; Sanders, D.A.; Whitfield, C.; McNeil, M.R.; Naismith, J.H. Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state. J. Mol. Biol. 2005, 348, 971-982.
-
(2005)
J. Mol. Biol.
, vol.348
, pp. 971-982
-
-
Beis, K.1
Srikannathasan, V.2
Liu, H.3
Fullerton, S.W.4
Bamford, V.A.5
Sanders, D.A.6
Whitfield, C.7
McNeil, M.R.8
Naismith, J.H.9
-
61
-
-
0034815662
-
UDP-galactopyranose mutase has a novel structure and mechanism
-
Sanders, D.A.; Staines, A.G.; McMahon, S.A.; McNeil, M.R.; Whitfield, C.; Naismith, J.H. UDP-galactopyranose mutase has a novel structure and mechanism. Nat. Struct. Biol. 2001, 8, 858-863.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 858-863
-
-
Sanders, D.A.1
Staines, A.G.2
McMahon, S.A.3
McNeil, M.R.4
Whitfield, C.5
Naismith, J.H.6
-
62
-
-
70349620864
-
X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin
-
Gruber, T.D.; Westler, W.M.; Kiessling, L.L.; Forest, K.T. X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin. Biochemistry 2009, 48, 9171-9173.
-
(2009)
Biochemistry
, vol.48
, pp. 9171-9173
-
-
Gruber, T.D.1
Westler, W.M.2
Kiessling, L.L.3
Forest, K.T.4
-
63
-
-
34250211471
-
Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues
-
Chad, J.M.; Sarathy, K.P.; Gruber, T.D.; Addala, E.; Kiessling, L.L.; Sanders, D.A. Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues. Biochemistry 2007, 46, 6723-6732.
-
(2007)
Biochemistry
, vol.46
, pp. 6723-6732
-
-
Chad, J.M.1
Sarathy, K.P.2
Gruber, T.D.3
Addala, E.4
Kiessling, L.L.5
Sanders, D.A.6
-
64
-
-
84858635325
-
Chemical mechanism of UDP-galactopyranose mutase from Trypanosoma cruzi: A potential drug target against Chagas' disease
-
Oppenheimer, M.; Valenciano, A.L.; Kizjakina, K.; Qi, J.; Sobrado, P. Chemical mechanism of UDP-galactopyranose mutase from Trypanosoma cruzi: A potential drug target against Chagas' disease. PLoS One 2012, 7, e32918.
-
(2012)
PLoS One
, vol.7
-
-
Oppenheimer, M.1
Valenciano, A.L.2
Kizjakina, K.3
Qi, J.4
Sobrado, P.5
-
65
-
-
79954615170
-
Isolation and characterization of functional Leishmania major virulence factor UDP-galactopyranose mutase
-
Oppenheimer, M.; Valenciano, A.L.; Sobrado, P. Isolation and characterization of functional Leishmania major virulence factor UDP-galactopyranose mutase. Biochem. Biophys. Res. Commun. 2011, 407, 552-556.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.407
, pp. 552-556
-
-
Oppenheimer, M.1
Valenciano, A.L.2
Sobrado, P.3
-
66
-
-
77956189386
-
Characterization of recombinant UDP-galactopyranose mutase from Aspergillus fumigatus
-
Oppenheimer, M.; Poulin, M.B.; Lowary, T.L.; Helm, R.F.; Sobrado, P. Characterization of recombinant UDP-galactopyranose mutase from Aspergillus fumigatus. Arch. Biochem. Biophys. 2010, 502, 31-38.
-
(2010)
Arch. Biochem. Biophys.
, vol.502
, pp. 31-38
-
-
Oppenheimer, M.1
Poulin, M.B.2
Lowary, T.L.3
Helm, R.F.4
Sobrado, P.5
-
67
-
-
0034721448
-
Studies of UDP-Galactopyranose mutase from Escherichia coli: An unusual role of reduced fad in its catalysis
-
Zhang, Q.; Liu, H.-W. Studies of UDP-Galactopyranose mutase from Escherichia coli: An unusual role of reduced fad in its catalysis. J. Am. CHem. Soc. 2000, 122, 9065-9070.
-
(2000)
J. Am. CHem. Soc.
, vol.122
, pp. 9065-9070
-
-
Zhang, Q.1
Liu, H.-W.2
-
68
-
-
0033612742
-
Positional Isotope Exchange Catalyzed by UDP-Galactopyranose Mutase
-
Barlow, J.N.; Girvin, M.E.; Blanchard, J. S Positional Isotope Exchange Catalyzed by UDP-Galactopyranose Mutase. J. Am. Chem. Soc. 1999, 121, 6968-6969.
-
(1999)
J. Am. Chem. Soc
, vol.121
, pp. 6968-6969
-
-
Barlow, J.N.1
Girvin, M.E.2
Blanchard, J.S.3
-
69
-
-
0034833650
-
Mechanistic investigation of UDP-galactopyranose mutase from Escherichia coli using 2-and 3-fluorinated UDP-galactofuranose as probes
-
Zhang, Q.; Liu, H. Mechanistic investigation of UDP-galactopyranose mutase from Escherichia coli using 2-and 3-fluorinated UDP-galactofuranose as probes. J. Am. Chem. Soc. 2001, 123, 6756-6766.
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 6756-6766
-
-
Zhang, Q.1
Liu, H.2
-
70
-
-
0344407501
-
Potentiometric analysis of UDP-galactopyranose mutase: Stabilization of the flavosemiquinone by substrate
-
Fullerton, S.W.; Daff, S.; Sanders, D.A.; Ingledew, W.J.; Whitfield, C.; Chapman, S.K.; Naismith, J.H. Potentiometric analysis of UDP-galactopyranose mutase: Stabilization of the flavosemiquinone by substrate. Biochemistry 2003, 42, 2104-2109.
-
(2003)
Biochemistry
, vol.42
, pp. 2104-2109
-
-
Fullerton, S.W.1
Daff, S.2
Sanders, D.A.3
Ingledew, W.J.4
Whitfield, C.5
Chapman, S.K.6
Naismith, J.H.7
-
71
-
-
0242468752
-
Reconstitution of UDP-galactopyranose mutase with 1-deaza-FAD and 5-deaza-FAD: Analysis and mechanistic implications
-
Huang, Z.; Zhang, Q.; Liu, H.W. Reconstitution of UDP-galactopyranose mutase with 1-deaza-FAD and 5-deaza-FAD: Analysis and mechanistic implications. Bioorg. Chem. 2003, 31, 494-502.
-
(2003)
Bioorg. Chem.
, vol.31
, pp. 494-502
-
-
Huang, Z.1
Zhang, Q.2
Liu, H.W.3
-
72
-
-
2542428317
-
A unique catalytic mechanism for UDP-galactopyranose mutase
-
Soltero-Higgin, M.; Carlson, E.E.; Gruber, T.D.; Kiessling, L.L. A unique catalytic mechanism for UDP-galactopyranose mutase. Nat. Struct. Mol. Biol. 2004, 11, 539-543.
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 539-543
-
-
Soltero-Higgin, M.1
Carlson, E.E.2
Gruber, T.D.3
Kiessling, L.L.4
-
73
-
-
31344462988
-
1,4-Anhydrogalactopyranose is not an intermediate of the mutase catalyzed UDP-galactopyranose/furanose interconversion
-
Caravano, A.; Sinay, P.; Vincent, S.P. 1,4-Anhydrogalactopyranose is not an intermediate of the mutase catalyzed UDP-galactopyranose/furanose interconversion. Bioorg. Med. Chem. Lett. 2006, 16, 1123-1125.
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 1123-1125
-
-
Caravano, A.1
Sinay, P.2
Vincent, S.P.3
-
74
-
-
0034612999
-
Enzymatic synthesis of UDP-(3-deoxy-3-fluoro)-D-galactose and UDP-(2-deoxy-2-fluoro)-D-galactose and substrate activity with UDP-galactopyranose mutase
-
Barlow, J.N.; Blanchard, J.S. Enzymatic synthesis of UDP-(3-deoxy-3-fluoro)-D-galactose and UDP-(2-deoxy-2-fluoro)-D-galactose and substrate activity with UDP-galactopyranose mutase. Carbohydr. Res. 2000, 328, 473-480.
-
(2000)
Carbohydr. Res.
, vol.328
, pp. 473-480
-
-
Barlow, J.N.1
Blanchard, J.S.2
-
75
-
-
70449674082
-
Structural basis of substrate binding to UDP-galactopyranose mutase: Crystal structures in the reduced and oxidized state complexed with UDP-galactopyranose and UDP
-
Partha, S.K.; van Straaten, K.E.; Sanders, D.A. Structural basis of substrate binding to UDP-galactopyranose mutase: Crystal structures in the reduced and oxidized state complexed with UDP-galactopyranose and UDP. J. Mol. Biol. 2009, 394, 864-877.
-
(2009)
J. Mol. Biol.
, vol.394
, pp. 864-877
-
-
Partha, S.K.1
van Straaten, K.E.2
Sanders, D.A.3
-
76
-
-
84859516039
-
Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatus
-
Van Straaten, K.E.; Routier, F.H.; Sanders, D.A. Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatus. J. Biol. Chem. 2012, 287, 10780-10790.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 10780-10790
-
-
van Straaten, K.E.1
Routier, F.H.2
Sanders, D.A.3
-
77
-
-
84863115242
-
Nucleophilic participation of reduced flavin coenzyme in mechanism of UDP-galactopyranose mutase
-
Sun, H.G.; Ruszczycky, M.W.; Chang, W.C.; Thibodeaux, C.J.; Liu, H.W. Nucleophilic participation of reduced flavin coenzyme in mechanism of UDP-galactopyranose mutase. J. Biol. Chem. 2012, 287, 4602-4608.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 4602-4608
-
-
Sun, H.G.1
Ruszczycky, M.W.2
Chang, W.C.3
Thibodeaux, C.J.4
Liu, H.W.5
-
78
-
-
0002336062
-
The Enzymatic Converstion of UDP-Galactopyranose to UDP-Galactofuranose
-
In Frey, P.A., Norththrop, D.B., Eds.; IOS Press: Amsterdam, The Netherland
-
Barlow, J.N.; Marcinkeviciene, J.; Blancherd, J.S. The Enzymatic Converstion of UDP-Galactopyranose to UDP-Galactofuranose. In Enzymatic Mechanims; Frey, P.A., Norththrop, D.B., Eds.; IOS Press: Amsterdam, The Netherland, 1999; pp. 98-106.
-
(1999)
Enzymatic Mechanims
, pp. 98-106
-
-
Barlow, J.N.1
Marcinkeviciene, J.2
Blancherd, J.S.3
-
79
-
-
0014919124
-
Acyl dihydroxyacetone phosphate: Precursor of alkyl ethers
-
Hajra, A.K. Acyl dihydroxyacetone phosphate: Precursor of alkyl ethers. Biochem. Biophys. Res. Commun. 1970, 39, 1037-1044.
-
(1970)
Biochem. Biophys. Res. Commun.
, vol.39
, pp. 1037-1044
-
-
Hajra, A.K.1
-
80
-
-
0024222978
-
Aberration in de novo ether lipid biosynthesis in peroxisomal disorders
-
Van den Bosch, H.; Schalkwijk, C.G.; Schrakamp, G.; Wanders, R.J.; Schutgens, R.B.; Schram, A.W.; Tager, J.M. Aberration in de novo ether lipid biosynthesis in peroxisomal disorders. Prog. Clin. Biol. Res. 1988, 282, 139-150.
-
(1988)
Prog. Clin. Biol. Res.
, vol.282
, pp. 139-150
-
-
van den Bosch, H.1
Schalkwijk, C.G.2
Schrakamp, G.3
Wanders, R.J.4
Schutgens, R.B.5
Schram, A.W.6
Tager, J.M.7
-
82
-
-
0034096194
-
Alkyl-dihydroxyacetonephosphate synthase. Presence and role of flavin adenine dinucleotide
-
De Vet, E.C.; Hilkes, Y.H.; Fraaije, M.W.; van den Bosch, H. Alkyl-dihydroxyacetonephosphate synthase. Presence and role of flavin adenine dinucleotide. J. Biol. Chem. 2000, 275, 6276-6283.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6276-6283
-
-
de Vet, E.C.1
Hilkes, Y.H.2
Fraaije, M.W.3
van den Bosch, H.4
-
83
-
-
0026735060
-
Biochemistry of peroxisomes
-
Van den Bosch, H.; Schutgens, R.B.; Wanders, R.J.; Tager, J.M. Biochemistry of peroxisomes. Annu. Rev. Biochem. 1992, 61, 157-197.
-
(1992)
Annu. Rev. Biochem.
, vol.61
, pp. 157-197
-
-
Van den Bosch, H.1
Schutgens, R.B.2
Wanders, R.J.3
Tager, J.M.4
-
84
-
-
0032693473
-
Ether lipid biosynthesis: Alkyl-dihydroxyacetonephosphate synthase protein deficiency leads to reduced dihydroxyacetonephosphate acyltransferase activities
-
De Vet, E.C.; Ijlst, L.; Oostheim, W.; Dekker, C.; Moser, H.W.; van Den Bosch, H.; Wanders, R.J. Ether lipid biosynthesis: Alkyl-dihydroxyacetonephosphate synthase protein deficiency leads to reduced dihydroxyacetonephosphate acyltransferase activities. J. Lipid Res. 1999, 40, 1998-2003.
-
(1999)
J. Lipid Res.
, vol.40
, pp. 1998-2003
-
-
de Vet, E.C.1
Ijlst, L.2
Oostheim, W.3
Dekker, C.4
Moser, H.W.5
van Den Bosch, H.6
Wanders, R.J.7
-
85
-
-
0042832489
-
Natural history of rhizomelic chondrodysplasia punctata
-
White, A.L.; Modaff, P.; Holland-Morris, F.; Pauli, R.M. Natural history of rhizomelic chondrodysplasia punctata. Am. J Med. Genet. 2003, 118A, 332-342.
-
(2003)
Am. J Med. Genet.
, vol.118 A
, pp. 332-342
-
-
White, A.L.1
Modaff, P.2
Holland-Morris, F.3
Pauli, R.M.4
-
86
-
-
34249898356
-
The crucial step in ether phospholipid biosynthesis: Structural basis of a noncanonical reaction associated with a peroxisomal disorder
-
Razeto, A.; Mattiroli, F.; Carpanelli, E.; Aliverti, A.; Pandini, V.; Coda, A.; Mattevi, A. The crucial step in ether phospholipid biosynthesis: Structural basis of a noncanonical reaction associated with a peroxisomal disorder. Structure 2007, 15, 683-692.
-
(2007)
Structure
, vol.15
, pp. 683-692
-
-
Razeto, A.1
Mattiroli, F.2
Carpanelli, E.3
Aliverti, A.4
Pandini, V.5
Coda, A.6
Mattevi, A.7
-
87
-
-
0033521696
-
Characterization of recombinant guinea pig alkyl-dihydroxyacetonephosphate synthase expressed in Escherichia coli. Kinetics, chemical modification and mutagenesis
-
De Vet, E.C.; van den Bosch, H. Characterization of recombinant guinea pig alkyl-dihydroxyacetonephosphate synthase expressed in Escherichia coli. Kinetics, chemical modification and mutagenesis. Biochim. Biophys. Acta 1999, 1436, 299-306.
-
(1999)
Biochim. Biophys. Acta
, vol.1436
, pp. 299-306
-
-
de Vet, E.C.1
van den Bosch, H.2
-
88
-
-
0032515348
-
Nucleotide sequence of a cDNA clone encoding a Caenorhabditis elegans homolog of mammalian alkyl-dihydroxyacetonephosphate synthase: Evolutionary switching of peroxisomal targeting signals
-
De Vet, E.C.; Prinsen, H.C.; van den Bosch, H. Nucleotide sequence of a cDNA clone encoding a Caenorhabditis elegans homolog of mammalian alkyl-dihydroxyacetonephosphate synthase: Evolutionary switching of peroxisomal targeting signals. Biochem. Biophys. Res. Commun. 1998, 242, 277-281.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.242
, pp. 277-281
-
-
de Vet, E.C.1
Prinsen, H.C.2
van den Bosch, H.3
-
89
-
-
0032573571
-
Nucleotide sequence of alkyl-dihydroxyacetonephosphate synthase cDNA from Dictyostelium discoideum
-
De Vet, E.C.; van den Bosch, H. Nucleotide sequence of alkyl-dihydroxyacetonephosphate synthase cDNA from Dictyostelium discoideum. Biochem. Biophys. Res. Commun. 1998, 252, 629-633.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.252
, pp. 629-633
-
-
de Vet, E.C.1
van den Bosch, H.2
-
90
-
-
0031576030
-
Nucleotide sequence of human alkyl-dihydroxyacetonephosphate synthase cDNA reveals the presence of a peroxisomal targeting signal 2
-
De Vet, E.C.; van den Broek, B.T.; van den Bosch, H. Nucleotide sequence of human alkyl-dihydroxyacetonephosphate synthase cDNA reveals the presence of a peroxisomal targeting signal 2. Biochim. Biophys. Acta 1997, 1346, 25-29.
-
(1997)
Biochim. Biophys. Acta
, vol.1346
, pp. 25-29
-
-
de Vet, E.C.1
van den Broek, B.T.2
van den Bosch, H.3
-
91
-
-
0020479415
-
Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism
-
Brown, A.J.; Snyder, F. Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism. J. Biol. Chem. 1982, 257, 8835-8839.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 8835-8839
-
-
Brown, A.J.1
Snyder, F.2
-
92
-
-
0018675816
-
Solubilization of alkyldihydroxyacetone-P synthase from Ehrlich ascites cell microsomal membranes
-
Brown, A.J.; Snyder, F. Solubilization of alkyldihydroxyacetone-P synthase from Ehrlich ascites cell microsomal membranes. Biochem. Biophys. Res. Commun. 1979, 90, 278-284.
-
(1979)
Biochem. Biophys. Res. Commun.
, vol.90
, pp. 278-284
-
-
Brown, A.J.1
Snyder, F.2
-
93
-
-
0016658056
-
The formation of tritiated O-alkyl lipid from acyldihydroxyacetone phosphate in the presence of tritiated water
-
Friedberg, S.J.; Heifetz, A. The formation of tritiated O-alkyl lipid from acyldihydroxyacetone phosphate in the presence of tritiated water. Biochemistry 1975, 14, 570-574.
-
(1975)
Biochemistry
, vol.14
, pp. 570-574
-
-
Friedberg, S.J.1
Heifetz, A.2
-
94
-
-
0015240201
-
Loss of hydrogen from dihydroxyacetone phosphate during glyceryl ether synthesis
-
Friedberg, S.J.; Heifetz, A.; Greene, R.C. Loss of hydrogen from dihydroxyacetone phosphate during glyceryl ether synthesis. J. Biol. Chem. 1971, 246, 5822-5827.
-
(1971)
J. Biol. Chem.
, vol.246
, pp. 5822-5827
-
-
Friedberg, S.J.1
Heifetz, A.2
Greene, R.C.3
-
95
-
-
0015514412
-
Studies on the mechanism of O-alkyl lipid synthesis
-
Friedberg, S.J.; Heifetz, A.; Greene, R.C. Studies on the mechanism of O-alkyl lipid synthesis. Biochemistry 1972, 11, 297-301.
-
(1972)
Biochemistry
, vol.11
, pp. 297-301
-
-
Friedberg, S.J.1
Heifetz, A.2
Greene, R.C.3
-
96
-
-
0022330703
-
Alkyldihydroxyacetonephosphate synthase mechanism: 18O studies of fatty acid release from acyldihydroxyacetone phosphate
-
Brown, A.J.; Glish, G.L.; McBay, E.H.; Snyder, F. Alkyldihydroxyacetonephosphate synthase mechanism: 18O studies of fatty acid release from acyldihydroxyacetone phosphate. Biochemistry 1985, 24, 8012-8016.
-
(1985)
Biochemistry
, vol.24
, pp. 8012-8016
-
-
Brown, A.J.1
Glish, G.L.2
McBay, E.H.3
Snyder, F.4
-
97
-
-
0020674635
-
The mechanism of ether bond formation in O-alkyl lipid synthesis in Ehrlich ascites tumor. Unusual cleavage of the fatty acid moiety of acyl dihydroxyacetone phosphate
-
Friedberg, S.J.; Weintraub, S.T.; Singer, M.R.; Greene, R.C. The mechanism of ether bond formation in O-alkyl lipid synthesis in Ehrlich ascites tumor. Unusual cleavage of the fatty acid moiety of acyl dihydroxyacetone phosphate. J. Biol. Chem. 1983, 258, 136-142.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 136-142
-
-
Friedberg, S.J.1
Weintraub, S.T.2
Singer, M.R.3
Greene, R.C.4
-
98
-
-
0032104191
-
A novel oxidoreductase family sharing a conserved FAD-binding domain
-
Fraaije, M.W.; van Berkel, W.J.; Benen, J.A.; Visser, J.; Mattevi, A. A novel oxidoreductase family sharing a conserved FAD-binding domain. Trends Biochem. Sci. 1998, 23, 206-207.
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 206-207
-
-
Fraaije, M.W.1
van Berkel, W.J.2
Benen, J.A.3
Visser, J.4
Mattevi, A.5
-
99
-
-
34548437444
-
Identifying a recombinant alkyldihydroxyacetonephosphate synthase suited for crystallographic studies
-
Razeto, A.; Mattiroli, F.; Bossi, R.; Coda, A.; Mattevi, A. Identifying a recombinant alkyldihydroxyacetonephosphate synthase suited for crystallographic studies. Protein Expr. Purif. 2007, 55, 343-351.
-
(2007)
Protein Expr. Purif.
, vol.55
, pp. 343-351
-
-
Razeto, A.1
Mattiroli, F.2
Bossi, R.3
Coda, A.4
Mattevi, A.5
-
100
-
-
0032574753
-
Biochemical and physical characterization of the active FAD-containing form of nitroalkane oxidase from Fusarium oxysporum
-
Gadda, G.; Fitzpatrick, P.F. Biochemical and physical characterization of the active FAD-containing form of nitroalkane oxidase from Fusarium oxysporum. Biochemistry 1998, 37, 6154-6164.
-
(1998)
Biochemistry
, vol.37
, pp. 6154-6164
-
-
Gadda, G.1
Fitzpatrick, P.F.2
-
101
-
-
0031054970
-
Identification of the naturally occurring flavin of nitroalkane oxidase from fusarium oxysporum as a 5-nitrobutyl-FAD and conversion of the enzyme to the active FAD-containing form
-
Gadda, G.; Edmondson, R.D.; Russell, D.H.; Fitzpatrick, P.F. Identification of the naturally occurring flavin of nitroalkane oxidase from fusarium oxysporum as a 5-nitrobutyl-FAD and conversion of the enzyme to the active FAD-containing form. J. Biol. Chem. 1997, 272, 5563-5570.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5563-5570
-
-
Gadda, G.1
Edmondson, R.D.2
Russell, D.H.3
Fitzpatrick, P.F.4
-
102
-
-
65249182105
-
Crystal Structures of Intermediates in the Nitroalkane Oxidase Reaction
-
Heroux, A.; Bozinovski, D.M.; Valley, M.P.; Fitzpatrick, P.F.; Orville, A.M. Crystal Structures of Intermediates in the Nitroalkane Oxidase Reaction. Biochemistry 2009, 48, 3407-3416.
-
(2009)
Biochemistry
, vol.48
, pp. 3407-3416
-
-
Heroux, A.1
Bozinovski, D.M.2
Valley, M.P.3
Fitzpatrick, P.F.4
Orville, A.M.5
-
103
-
-
31544467044
-
Crystal structures of nitroalkane oxidase: Insights into the reaction mechanism from a covalent complex of the flavoenzyme trapped during turnover
-
Nagpal, A.; Valley, M.P.; Fitzpatrick, P.F.; Orville, A.M. Crystal structures of nitroalkane oxidase: Insights into the reaction mechanism from a covalent complex of the flavoenzyme trapped during turnover. Biochemistry 2006, 45, 1138-1150.
-
(2006)
Biochemistry
, vol.45
, pp. 1138-1150
-
-
Nagpal, A.1
Valley, M.P.2
Fitzpatrick, P.F.3
Orville, A.M.4
-
104
-
-
9744277560
-
Nitroalkane oxidase, a carbanion-forming flavoprotein homologous to acyl-CoA dehydrogenase
-
Fitzpatrick, P.F.; Orville, A.M.; Nagpal, A.; Valley, M.P. Nitroalkane oxidase, a carbanion-forming flavoprotein homologous to acyl-CoA dehydrogenase. Arch. Biochem. Biophys. 2005, 433, 157-165.
-
(2005)
Arch. Biochem. Biophys.
, vol.433
, pp. 157-165
-
-
Fitzpatrick, P.F.1
Orville, A.M.2
Nagpal, A.3
Valley, M.P.4
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