Crystal Structures of Monoamine Oxidase B in Complex with Four Inhibitors of the N-Propargylaminoindan Class

Journal of Medicinal Chemistry

Volumn 47, Issue 7, 2004, Pages 1767-1774

  Binda, Claudia ^a   Hubálek, Frantisek ^b   Li, Min ^b   Herzig, Yaacov ^c   Sterling, Jeffrey ^c   Edmondson, Dale E ^b   Mattevi, Andrea ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Research and Development Division   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

6 HYDROXY N PROPARGYLAMINE 1 AMINOINDAN; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; MEMBRANE ENZYME; MONOAMINE OXIDASE B INHIBITOR; N METHYL N PROPARGYLAMINOINDAN; NEUROTRANSMITTER; RASAGILINE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; DRUG BINDING; DRUG CONFORMATION; DRUG DESIGN; DRUG SELECTIVITY; DRUG STRUCTURE; HYDROGEN BOND;

ALKYNES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; INDANS; KINETICS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 12144289182     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm031087c     Document Type: Article

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