The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death

EMBO Journal

Volumn 36, Issue 9, 2017, Pages 1147-1166

  Lafont, Elodie ^a   Kantari Mimoun, Chahrazade ^a   Draber, Peter ^a   De Miguel, Diego ^a   Hartwig, Torsten ^a   Reichert, Matthias ^a   Kupka, Sebastian ^a   Shimizu, Yutaka ^a   Taraborrelli, Lucia ^a   Spit, Maureen ^a   Sprick, Martin R ^b   Walczak, Henning ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Hi STEM Heidelberg Institute for Stem Cell Technology and Experimental Medicine GmbH   (Germany)

Author keywords

cell death; LUBAC; NF B; TRAIL; ubiquitin

Indexed keywords

CASPASE 10; CASPASE 8; CIAP1 PROTEIN; CIAP2 PROTEIN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; HOIP PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LINEAR UBIQUITIN CHAIN ASSEMBLY COMPLEX; MLKL PROTEIN; PROTEIN; RIPK1 PROTEIN; RIPK3 PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; TNFSF10 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR; UBIQUITIN PROTEIN LIGASE;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE ACTIVATION; HUMAN; HUMAN CELL; NECROPTOSIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PROTEIN TARGETING; UBIQUITINATION; CELL LINE; METABOLISM; TRANSCRIPTION INITIATION;

CELL DEATH; CELL LINE; HUMANS; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSCRIPTIONAL ACTIVATION; UBIQUITIN-PROTEIN LIGASES;

EID: 85014084788     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201695699     Document Type: Article

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