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Volumn 3, Issue 10, 2012, Pages

The adaptor protein FADD and the initiator caspase-8 mediate activation of NF-κB by TRAIL

Author keywords

Death receptor; DISC; NF B; p65; Signaling

Indexed keywords

CASPASE 8; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FLICE INHIBITORY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RECEPTOR INTERACTING PROTEIN 140; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 84870478634     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.154     Document Type: Article
Times cited : (49)

References (40)
  • 1
    • 0031405585 scopus 로고    scopus 로고
    • TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB
    • Schneider P, Thome M, Burns K, Bodmer JL, Hofmann K, Kataoka T et al. TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB. Immunity 1997; 7: 831-836.
    • (1997) Immunity , vol.7 , pp. 831-836
    • Schneider, P.1    Thome, M.2    Burns, K.3    Bodmer, J.L.4    Hofmann, K.5    Kataoka, T.6
  • 2
    • 77956170550 scopus 로고    scopus 로고
    • New insights into apoptosis signaling by Apo2L/TRAIL
    • Gonzalvez F, Ashkenazi A. New insights into apoptosis signaling by Apo2L/TRAIL. Oncogene 2010; 29: 4752-4765.
    • (2010) Oncogene , vol.29 , pp. 4752-4765
    • Gonzalvez, F.1    Ashkenazi, A.2
  • 3
    • 3543096349 scopus 로고    scopus 로고
    • NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP
    • Kreuz S, Siegmund D, Rumpf JJ, Samel D, Leverkus M, Janssen O et al. NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP. J Cell Biol 2004; 166: 369-380.
    • (2004) J Cell Biol , vol.166 , pp. 369-380
    • Kreuz, S.1    Siegmund, D.2    Rumpf, J.J.3    Samel, D.4    Leverkus, M.5    Janssen, O.6
  • 4
    • 23944514831 scopus 로고    scopus 로고
    • FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells
    • Pellegrini M, Bath S, Marsden VS, Huang DC, Metcalf D, Harris AW et al. FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells. Blood 2005; 106: 1581-1589.
    • (2005) Blood , vol.106 , pp. 1581-1589
    • Pellegrini, M.1    Bath, S.2    Marsden, V.S.3    Huang, D.C.4    Metcalf, D.5    Harris, A.W.6
  • 5
    • 7144263731 scopus 로고    scopus 로고
    • FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis
    • Yeh WC, Pompa JL, McCurrach ME, Shu HB, Elia AJ, Shahinian A et al. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 1998; 279: 1954-1958.
    • (1998) Science , vol.279 , pp. 1954-1958
    • Yeh, W.C.1    Pompa, J.L.2    McCurrach, M.E.3    Shu, H.B.4    Elia, A.J.5    Shahinian, A.6
  • 6
    • 79952810024 scopus 로고    scopus 로고
    • Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
    • Oberst A, Dillon CP, Weinlich R, McCormick LL, Fitzgerald P, Pop C et al. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 2011; 471: 363-367.
    • (2011) Nature , vol.471 , pp. 363-367
    • Oberst, A.1    Dillon, C.P.2    Weinlich, R.3    McCormick, L.L.4    Fitzgerald, P.5    Pop, C.6
  • 8
    • 0036848180 scopus 로고    scopus 로고
    • Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart
    • Sakamaki K, Inoue T, Asano M, Sudo K, Kazama H, Sakagami J et al. Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart. Cell Death Differ 2002; 9: 1196-1206.
    • (2002) Cell Death Differ , vol.9 , pp. 1196-1206
    • Sakamaki, K.1    Inoue, T.2    Asano, M.3    Sudo, K.4    Kazama, H.5    Sakagami, J.6
  • 9
    • 0038414629 scopus 로고    scopus 로고
    • TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways
    • Secchiero P, Gonelli A, Carnevale E, Milani D, Pandolfi A, Zella D et al. TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways. Circulation 2003; 107: 2250-2256.
    • (2003) Circulation , vol.107 , pp. 2250-2256
    • Secchiero, P.1    Gonelli, A.2    Carnevale, E.3    Milani, D.4    Pandolfi, A.5    Zella, D.6
  • 10
    • 0031810458 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappaB activation attenuates apoptosis resistance in lymphoid cells
    • Jeremias I, Kupatt C, Baumann B, Herr I, Wirth T, Debatin KM. Inhibition of nuclear factor kappaB activation attenuates apoptosis resistance in lymphoid cells. Blood 1998; 91: 4624-4631.
    • (1998) Blood , vol.91 , pp. 4624-4631
    • Jeremias, I.1    Kupatt, C.2    Baumann, B.3    Herr, I.4    Wirth, T.5    Debatin, K.M.6
  • 11
    • 0038339094 scopus 로고    scopus 로고
    • TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB
    • Ehrhardt H, Fulda S, Schmid I, Hiscott J, Debatin KM, Jeremias I. TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB. Oncogene 2003; 22: 3842-3852.
    • (2003) Oncogene , vol.22 , pp. 3842-3852
    • Ehrhardt, H.1    Fulda, S.2    Schmid, I.3    Hiscott, J.4    Debatin, K.M.5    Jeremias, I.6
  • 12
    • 24744462114 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand-mediated proliferation of tumor cells with receptorproximal apoptosis defects
    • Baader E, Toloczko A, Fuchs U, Schmid I, Beltinger C, Ehrhardt H et al. Tumor necrosis factor-related apoptosis-inducing ligand-mediated proliferation of tumor cells with receptorproximal apoptosis defects. Cancer Res 2005; 65: 7888-7895.
    • (2005) Cancer Res , vol.65 , pp. 7888-7895
    • Baader, E.1    Toloczko, A.2    Fuchs, U.3    Schmid, I.4    Beltinger, C.5    Ehrhardt, H.6
  • 13
    • 0033821215 scopus 로고    scopus 로고
    • The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase
    • Lin Y, Devin A, Cook A, Keane MM, Kelliher M, Lipkowitz S et al. The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase. Mol Cell Biol 2000; 20: 6638-6645.
    • (2000) Mol Cell Biol , vol.20 , pp. 6638-6645
    • Lin, Y.1    Devin, A.2    Cook, A.3    Keane, M.M.4    Kelliher, M.5    Lipkowitz, S.6
  • 14
    • 79960341239 scopus 로고    scopus 로고
    • TRADD is critical for resistance to TRAIL-induced cell death through NF-kappaB activation
    • Kim JY, Lee JY, Kim DG, Koo GB, Yu JW, Kim YS. TRADD is critical for resistance to TRAIL-induced cell death through NF-kappaB activation. FEBS Lett 2011; 585: 2144-2150.
    • (2011) FEBS Lett , vol.585 , pp. 2144-2150
    • Kim, J.Y.1    Lee, J.Y.2    Kim, D.G.3    Koo, G.B.4    Yu, J.W.5    Kim, Y.S.6
  • 15
    • 38949176077 scopus 로고    scopus 로고
    • The viral oncoprotein LMP1 exploits TRADD for signaling by masking its apoptotic activity
    • Schneider F, Neugebauer J, Griese J, Liefold N, Kutz H, Briseno C et al. The viral oncoprotein LMP1 exploits TRADD for signaling by masking its apoptotic activity. PLoS Biol 2008; 6: e8.
    • (2008) PLoS Biol , vol.6
    • Schneider, F.1    Neugebauer, J.2    Griese, J.3    Liefold, N.4    Kutz, H.5    Briseno, C.6
  • 16
    • 0031939402 scopus 로고    scopus 로고
    • A fusion of the EBV latent membrane protein-1 (LMP1) transmembrane domains to the CD40 cytoplasmic domain is similar to LMP1 in constitutive activation of epidermal growth factor receptor expression, nuclear factor-kappa B, and stress-activated protein kinase
    • Hatzivassiliou E, Miller WE, Raab-Traub N, Kieff E, Mosialos G. A fusion of the EBV latent membrane protein-1 (LMP1) transmembrane domains to the CD40 cytoplasmic domain is similar to LMP1 in constitutive activation of epidermal growth factor receptor expression, nuclear factor-kappa B, and stress-activated protein kinase. J Immunol 1998; 160: 1116-1121.
    • (1998) J Immunol , vol.160 , pp. 1116-1121
    • Hatzivassiliou, E.1    Miller, W.E.2    Raab-Traub, N.3    Kieff, E.4    Mosialos, G.5
  • 17
    • 0031406386 scopus 로고    scopus 로고
    • Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway
    • Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity 1997; 7: 821-830.
    • (1997) Immunity , vol.7 , pp. 821-830
    • Chaudhary, P.M.1    Eby, M.2    Jasmin, A.3    Bookwalter, A.4    Murray, J.5    Hood, L.6
  • 19
    • 0034617304 scopus 로고    scopus 로고
    • Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL
    • Bodmer JL, Meier P, Tschopp J, Schneider P. Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL. J Biol Chem 2000; 275: 20632-20637.
    • (2000) J Biol Chem , vol.275 , pp. 20632-20637
    • Bodmer, J.L.1    Meier, P.2    Tschopp, J.3    Schneider, P.4
  • 20
    • 34548125801 scopus 로고    scopus 로고
    • Overexpression and refolding of thioredoxin/TRAIL fusion from inclusion bodies and further purification of TRAIL after cleavage by enteropeptidase
    • Gasparian ME, Ostapchenko VG, Yagolovich AV, Tsygannik IN, Chernyak BV, Dolgikh DA et al. Overexpression and refolding of thioredoxin/TRAIL fusion from inclusion bodies and further purification of TRAIL after cleavage by enteropeptidase. Biotechnol Lett 2007; 29: 1567-1573.
    • (2007) Biotechnol Lett , vol.29 , pp. 1567-1573
    • Gasparian, M.E.1    Ostapchenko, V.G.2    Yagolovich, A.V.3    Tsygannik, I.N.4    Chernyak, B.V.5    Dolgikh, D.A.6
  • 22
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • Hsu H, Shu HB, Pan MG, Goeddel DV. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 1996; 84: 299-308.
    • (1996) Cell , vol.84 , pp. 299-308
    • Hsu, H.1    Shu, H.B.2    Pan, M.G.3    Goeddel, D.V.4
  • 23
    • 33744517489 scopus 로고    scopus 로고
    • Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis
    • Muppidi JR, Lobito AA, Ramaswamy M, Yang JK, Wang L, Wu H et al. Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis. Cell Death Differ 2006; 13: 1641-1650.
    • (2006) Cell Death Differ , vol.13 , pp. 1641-1650
    • Muppidi, J.R.1    Lobito, A.A.2    Ramaswamy, M.3    Yang, J.K.4    Wang, L.5    Wu, H.6
  • 24
    • 33748195107 scopus 로고    scopus 로고
    • A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules
    • Banaszynski LA, Chen LC, Maynard-Smith LA, Ooi AG, Wandless TJ. A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules. Cell 2006; 126: 995-1004.
    • (2006) Cell , vol.126 , pp. 995-1004
    • Banaszynski, L.A.1    Chen, L.C.2    Maynard-Smith, L.A.3    Ooi, A.G.4    Wandless, T.J.5
  • 25
    • 5944233768 scopus 로고    scopus 로고
    • Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
    • Holler N, Zaru R, Micheau O, Thome M, Attinger A, Valitutti S et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 2000; 1: 489-495.
    • (2000) Nat Immunol , vol.1 , pp. 489-495
    • Holler, N.1    Zaru, R.2    Micheau, O.3    Thome, M.4    Attinger, A.5    Valitutti, S.6
  • 26
    • 0029858348 scopus 로고    scopus 로고
    • RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis
    • Ting AT, Pimentel-Muinos FX, Seed B. RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis. EMBO J 1996; 15: 6189-6196.
    • (1996) EMBO J , vol.15 , pp. 6189-6196
    • Ting, A.T.1    Pimentel-Muinos, F.X.2    Seed, B.3
  • 27
    • 11144224085 scopus 로고    scopus 로고
    • CFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes
    • Wachter T, Sprick M, Hausmann D, Kerstan A, McPherson K, Stassi G et al. cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes. J Biol Chem 2004; 279: 52824-52834.
    • (2004) J Biol Chem , vol.279 , pp. 52824-52834
    • Wachter, T.1    Sprick, M.2    Hausmann, D.3    Kerstan, A.4    McPherson, K.5    Stassi, G.6
  • 28
    • 79955761920 scopus 로고    scopus 로고
    • Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95-and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex
    • Kavuri SM, Geserick P, Berg D, Dimitrova DP, Feoktistova M, Siegmund D et al. Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95-and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex. J Biol Chem 2011; 286: 16631-16646.
    • (2011) J Biol Chem , vol.286 , pp. 16631-16646
    • Kavuri, S.M.1    Geserick, P.2    Berg, D.3    Dimitrova, D.P.4    Feoktistova, M.5    Siegmund, D.6
  • 29
    • 0032505127 scopus 로고    scopus 로고
    • Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade
    • Juo P, Kuo CJ, Yuan J, Blenis J. Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade. Curr Biol 1998; 8: 1001-1008.
    • (1998) Curr Biol , vol.8 , pp. 1001-1008
    • Juo, P.1    Kuo, C.J.2    Yuan, J.3    Blenis, J.4
  • 30
    • 77949405660 scopus 로고    scopus 로고
    • Dynamics within the CD95 death-inducing signaling complex decide life and death of cells
    • Neumann L, Pforr C, Beaudouin J, Pappa A, Fricker N, Krammer PH et al. Dynamics within the CD95 death-inducing signaling complex decide life and death of cells. Mol Syst Biol 2010; 6: 352.
    • (2010) Mol Syst Biol , vol.6 , pp. 352
    • Neumann, L.1    Pforr, C.2    Beaudouin, J.3    Pappa, A.4    Fricker, N.5    Krammer, P.H.6
  • 31
    • 58149154792 scopus 로고    scopus 로고
    • Tumour necrosis factorrelated apoptosis-inducing ligand (TRAIL)-induced chemokine release in both TRAIL-resistant and TRAIL-sensitive cells via nuclear factor kappa B
    • Tang W, Wang W, Zhang Y, Liu S, Liu Y, Zheng D. Tumour necrosis factorrelated apoptosis-inducing ligand (TRAIL)-induced chemokine release in both TRAIL-resistant and TRAIL-sensitive cells via nuclear factor kappa B. FEBS J 2009; 276: 581-593.
    • (2009) FEBS J , vol.276 , pp. 581-593
    • Tang, W.1    Wang, W.2    Zhang, Y.3    Liu, S.4    Liu, Y.5    Zheng, D.6
  • 32
    • 28844441555 scopus 로고    scopus 로고
    • Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
    • Varfolomeev E, Maecker H, Sharp D, Lawrence D, Renz M, Vucic D et al. Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J Biol Chem 2005; 280: 40599-40608.
    • (2005) J Biol Chem , vol.280 , pp. 40599-40608
    • Varfolomeev, E.1    Maecker, H.2    Sharp, D.3    Lawrence, D.4    Renz, M.5    Vucic, D.6
  • 33
    • 79954618079 scopus 로고    scopus 로고
    • The role of TRADD in TRAIL-induced apoptosis and signaling
    • Cao X, Pobezinskaya YL, Morgan MJ, Liu Z-g. The role of TRADD in TRAIL-induced apoptosis and signaling. FASEB J 2011; 25: 1353-1358.
    • (2011) FASEB J , vol.25 , pp. 1353-1358
    • Cao, X.1    Pobezinskaya, Y.L.2    Morgan, M.J.3    Liu, Z.-G.4
  • 34
    • 54049086943 scopus 로고    scopus 로고
    • Pursuing different 'TRADDes': TRADD signaling induced by TNF-receptor 1 and the Epstein-Barr virus oncoprotein LMP1
    • Kieser A. Pursuing different 'TRADDes': TRADD signaling induced by TNF-receptor 1 and the Epstein-Barr virus oncoprotein LMP1. Biol Chem 2008; 389: 1261-1271.
    • (2008) Biol Chem , vol.389 , pp. 1261-1271
    • Kieser, A.1
  • 35
    • 79952498248 scopus 로고    scopus 로고
    • TNFR1-induced activation of the classical NF-κB pathway
    • Wajant H, Scheurich P. TNFR1-induced activation of the classical NF-κB pathway. FEBS J 2011; 278: 862-876.
    • (2011) FEBS J , vol.278 , pp. 862-876
    • Wajant, H.1    Scheurich, P.2
  • 36
    • 0036143575 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells
    • Choi C, Kutsch O, Park J, Zhou T, Seol DW, Benveniste EN. Tumor necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells. Mol Cell Biol 2002; 22: 724-736.
    • (2002) Mol Cell Biol , vol.22 , pp. 724-736
    • Choi, C.1    Kutsch, O.2    Park, J.3    Zhou, T.4    Seol, D.W.5    Benveniste, E.N.6
  • 37
    • 0035860696 scopus 로고    scopus 로고
    • Modulation of tumor necrosis factor apoptosis-inducing ligand-induced NF-kappa B activation by inhibition of apical caspases
    • Harper N, Farrow SN, Kaptein A, Cohen GM, MacFarlane M. Modulation of tumor necrosis factor apoptosis-inducing ligand-induced NF-kappa B activation by inhibition of apical caspases. J Biol Chem 2001; 276: 34743-34752.
    • (2001) J Biol Chem , vol.276 , pp. 34743-34752
    • Harper, N.1    Farrow, S.N.2    Kaptein, A.3    Cohen, G.M.4    MacFarlane, M.5
  • 38
    • 0034637585 scopus 로고    scopus 로고
    • Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of fas-associated death domain protein (FADD)
    • Wajant H, Haas E, Schwenzer R, Mühlenbeck F, Kreuz S, Schubert G et al. Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of fas-associated death domain protein (FADD). J Biol Chem 2000; 275: 24357-24366.
    • (2000) J Biol Chem , vol.275 , pp. 24357-24366
    • Wajant, H.1    Haas, E.2    Schwenzer, R.3    Mühlenbeck, F.4    Kreuz, S.5    Schubert, G.6
  • 39
  • 40
    • 33750370438 scopus 로고    scopus 로고
    • Distinct signaling pathways in TRAIL-versus tumor necrosis factor-induced apoptosis
    • Jin Z, El-Deiry WS. Distinct signaling pathways in TRAIL-versus tumor necrosis factor-induced apoptosis. Mol Cell Biol 2006; 26: 8136-8148.
    • (2006) Mol Cell Biol , vol.26 , pp. 8136-8148
    • Jin, Z.1    El-Deiry, W.S.2


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