Mechanism underlying IκB kinase activation mediated by the linear ubiquitin chain assembly complex

Molecular and Cellular Biology

Volumn 34, Issue 7, 2014, Pages 1322-1335

  Fujita, Hiroaki ^a,b   Rahighi, Simin ^c,d   Akita, Mariko ^a   Kato, Ryuichi ^c   Sasaki, Yoshiteru ^b   Wakatsuki, Soichi ^c,d,e   Iwaia, Kazuhiro ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c INSTITUTE OF MATERIALS STRUCTURE SCIENCE   (Japan)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HOIL IL PROTEIN; HOIP PROTEIN; I KAPPA B KINASE; I KAPPA B KINASE 2; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGASE; LINEAR UBIQUITIN CHAIN ASSEMBLY COMPLEX LIGASE; MUTANT PROTEIN; POLYUBIQUITIN; SHARPIN PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CC2 LZ DOMAIN; CONJUGATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; EMBRYO; ENZYME ACTIVATION; ENZYME SUBUNIT; IKK2 KINASE DOMAIN; IN VITRO STUDY; LINEAR POLYUBIQUITINATION; MOLECULAR RECOGNITION; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; NPL4 ZINC FINGER 1 DOMAIN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELLS, CULTURED; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; I-KAPPA B KINASE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; NF-KAPPA B; PHOSPHORYLATION; POLYUBIQUITIN; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; UBIQUITIN-PROTEIN LIGASES;

EID: 84895822094     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01538-13     Document Type: Article

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