메뉴 건너뛰기




Volumn 9, Issue 1, 2016, Pages 13-29

Current and emerging uses of statins in clinical therapeutics: A review

Author keywords

Adverse effects; Atherosclerotic cardiovascular disease; Autoimmune and chronic inflammatory diseases; Cancer; Low density lipoprotein cholesterol; Statins

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN;

EID: 85013422908     PISSN: None     EISSN: 11786353     Source Type: Journal    
DOI: 10.4137/LPI.S37450     Document Type: Article
Times cited : (126)

References (191)
  • 1
    • 84938057928 scopus 로고    scopus 로고
    • Global overview of the epidemiology of atherosclerotic cardiovascular disease
    • Barquera S, Pedroza-Tobias A, Medina C, et al. Global overview of the epidemiology of atherosclerotic cardiovascular disease. Arch Med Res. 2015;46(5):328-338.
    • (2015) Arch Med Res. , vol.46 , Issue.5 , pp. 328-338
    • Barquera, S.1    Pedroza-Tobias, A.2    Medina, C.3
  • 3
    • 84897970506 scopus 로고    scopus 로고
    • 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    • Stone NJ, Robinson JG, Lichtenstein AH, et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;129(25 suppl 2): S1-S45.
    • (2014) Circulation. , vol.129 , Issue.2 , pp. S1-S45
    • Stone, N.J.1    Robinson, J.G.2    Lichtenstein, A.H.3
  • 4
    • 77955114517 scopus 로고    scopus 로고
    • A historical perspective on the discovery of statins
    • Endo A. A historical perspective on the discovery of statins. Proc Jpn Acad Ser B Phys Biol Sci. 2010;86(5):484-493.
    • (2010) Proc Jpn Acad Ser B Phys Biol Sci. , vol.86 , Issue.5 , pp. 484-493
    • Endo, A.1
  • 5
    • 4644327186 scopus 로고    scopus 로고
    • Cardiovascular disease: different strategies for primary and secondary prevention?
    • Hobbs FD. Cardiovascular disease: different strategies for primary and secondary prevention? Heart. 2004;90(10):1217-1223.
    • (2004) Heart. , vol.90 , Issue.10 , pp. 1217-1223
    • Hobbs, F.D.1
  • 6
    • 84898721405 scopus 로고    scopus 로고
    • Application of new cholesterol guidelines to a population-based sample
    • Pencina MJ, Navar-Boggan AM, D'Agostino RB Sr, et al. Application of new cholesterol guidelines to a population-based sample. N Engl J Med. 2014;370(15): 1422-1431.
    • (2014) N Engl J Med. , vol.370 , Issue.15 , pp. 1422-1431
    • Pencina, M.J.1    Navar-Boggan, A.M.2    D'Agostino R.B, Sr.3
  • 8
    • 84960810749 scopus 로고    scopus 로고
    • New therapeutic approaches to the treatment of dyslipidemia
    • Rader DJ. New therapeutic approaches to the treatment of dyslipidemia. Cell Metab. 2016;23(3):405-412.
    • (2016) Cell Metab. , vol.23 , Issue.3 , pp. 405-412
    • Rader, D.J.1
  • 9
    • 84971340474 scopus 로고    scopus 로고
    • Introduction to lipids and lipoproteins
    • [Updated 2015 Jun 10]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al editors. Endotext. [Internet] South Dartmouth, MA: MDText.com, Inc.; 2000.
    • Feingold KR, Grunfeld C. Introduction to lipids and lipoproteins. [Updated 2015 Jun 10]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al editors. Endotext. [Internet] South Dartmouth, MA: MDText.com, Inc.; 2000.
    • Feingold, K.R.1    Grunfeld, C.2
  • 11
    • 84933673677 scopus 로고    scopus 로고
    • Efficacy and safety of LDL-lowering therapy among men and women: metaanalysis of individual data from 174,000 participants in 27 randomised trials
    • Cholesterol Treatment Trialists' (CTT) Collaboration, Fulcher J, O'Connell R, et al. Efficacy and safety of LDL-lowering therapy among men and women: metaanalysis of individual data from 174,000 participants in 27 randomised trials. Lancet. 2015;385(9976):1397-1405.
    • (2015) Lancet. , vol.385 , Issue.9976 , pp. 1397-1405
    • Fulcher, J.1    O'Connell, R.2
  • 12
    • 84908505976 scopus 로고    scopus 로고
    • Resistance and intolerance to statins
    • Reiner Z. Resistance and intolerance to statins. Nutr Metab Cardiovasc Dis. 2014; 24(10):1057-1066.
    • (2014) Nutr Metab Cardiovasc Dis. , vol.24 , Issue.10 , pp. 1057-1066
    • Reiner, Z.1
  • 13
    • 84925351969 scopus 로고    scopus 로고
    • Lipid lowering with PCSK9 inhibitors
    • Dadu RT, Ballantyne CM. Lipid lowering with PCSK9 inhibitors. Nat Rev Cardiol. 2014;11(10):563-575.
    • (2014) Nat Rev Cardiol. , vol.11 , Issue.10 , pp. 563-575
    • Dadu, R.T.1    Ballantyne, C.M.2
  • 14
    • 34548328972 scopus 로고    scopus 로고
    • Effectiveness of altering serum cholesterol levels without drugs
    • Rosenthal RL. Effectiveness of altering serum cholesterol levels without drugs. Proc (Bayl Univ Med Cent). 2000;13(4):351-355.
    • (2000) Proc (Bayl Univ Med Cent). , vol.13 , Issue.4 , pp. 351-355
    • Rosenthal, R.L.1
  • 15
    • 0026551567 scopus 로고
    • Effects of weight-loss by exercise and by diet on apolipoproteins A-I and A-II and the particle- size distribution of high-density lipoproteins in men
    • Williams PT, Krauss RM, Vranizan KM, Albers JJ, Wood PD. Effects of weight-loss by exercise and by diet on apolipoproteins A-I and A-II and the particle- size distribution of high-density lipoproteins in men. Metabolism. 1992;41(4): 441-449.
    • (1992) Metabolism. , vol.41 , Issue.4 , pp. 441-449
    • Williams, P.T.1    Krauss, R.M.2    Vranizan, K.M.3    Albers, J.J.4    Wood, P.D.5
  • 16
    • 84887828771 scopus 로고    scopus 로고
    • 'Mediterranean' dietary pattern for the primary prevention of cardiovascular disease
    • Rees K, Hartley L, Flowers N, et al. 'Mediterranean' dietary pattern for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2013;(8): CD009825.
    • (2013) Cochrane Database Syst Rev. , Issue.8
    • Rees, K.1    Hartley, L.2    Flowers, N.3
  • 17
    • 0028897716 scopus 로고
    • Women and men with hypercholesterolemia respond similarly to an American Heart Association step 1 diet
    • Geil PB, Anderson JW, Gustafson NJ. Women and men with hypercholesterolemia respond similarly to an American Heart Association step 1 diet. J Am Diet Assoc. 1995;95(4):436-441.
    • (1995) J Am Diet Assoc. , vol.95 , Issue.4 , pp. 436-441
    • Geil, P.B.1    Anderson, J.W.2    Gustafson, N.J.3
  • 18
    • 62749121591 scopus 로고    scopus 로고
    • Comparative effects of three popular diets on lipids, endothelial function, and C-reactive protein during weight maintenance
    • Miller M, Beach V, Sorkin JD, et al. Comparative effects of three popular diets on lipids, endothelial function, and C-reactive protein during weight maintenance. J Am Diet Assoc. 2009;109(4):713-717.
    • (2009) J Am Diet Assoc. , vol.109 , Issue.4 , pp. 713-717
    • Miller, M.1    Beach, V.2    Sorkin, J.D.3
  • 19
    • 0035528772 scopus 로고    scopus 로고
    • Statins: mechanism of action and effects
    • Stancu C, Sima A. Statins: mechanism of action and effects. J Cell Mol Med. 2001;5(4):378-387.
    • (2001) J Cell Mol Med. , vol.5 , Issue.4 , pp. 378-387
    • Stancu, C.1    Sima, A.2
  • 20
    • 84908289985 scopus 로고    scopus 로고
    • Low-risk diet and lifestyle habits in the primary prevention of myocardial infarction in men: a populationbased prospective cohort study
    • Akesson A, Larsson SC, Discacciati A, Wolk A. Low-risk diet and lifestyle habits in the primary prevention of myocardial infarction in men: a populationbased prospective cohort study. J Am Coll Cardiol. 2014;64(13):1299-1306.
    • (2014) J Am Coll Cardiol. , vol.64 , Issue.13 , pp. 1299-1306
    • Akesson, A.1    Larsson, S.C.2    Discacciati, A.3    Wolk, A.4
  • 21
    • 85006216306 scopus 로고    scopus 로고
    • Comparative effectiveness of personalized lifestyle management strategies for cardiovascular disease risk reduction
    • Chu P, Pandya A, Salomon JA, Goldie SJ, Hunink MG. Comparative effectiveness of personalized lifestyle management strategies for cardiovascular disease risk reduction. J Am Heart Assoc. 2016;4(3):e002737.
    • (2016) J Am Heart Assoc. , vol.4 , Issue.3
    • Chu, P.1    Pandya, A.2    Salomon, J.A.3    Goldie, S.J.4    Hunink, M.G.5
  • 22
    • 84936154718 scopus 로고    scopus 로고
    • The national physical activity plan: a call to action from the American Heart Association: a science advisory from the American Heart Association
    • Kraus WE, Bittner V, Appel L, et al. The national physical activity plan: a call to action from the American Heart Association: a science advisory from the American Heart Association. Circulation. 2015;131(21):1932-1940.
    • (2015) Circulation. , vol.131 , Issue.21 , pp. 1932-1940
    • Kraus, W.E.1    Bittner, V.2    Appel, L.3
  • 23
    • 84925283913 scopus 로고    scopus 로고
    • Cardiovascular health and protection against CVD: more than the sum of the parts?
    • Lloyd-Jones DM. Cardiovascular health and protection against CVD: more than the sum of the parts? Circulation. 2014;130(19):1671-1673.
    • (2014) Circulation. , vol.130 , Issue.19 , pp. 1671-1673
    • Lloyd-Jones, D.M.1
  • 24
    • 59549089180 scopus 로고    scopus 로고
    • Statin adverse effects: a review of the literature and evidence for a mitochondrial mechanism
    • Golomb BA, Evans MA. Statin adverse effects: a review of the literature and evidence for a mitochondrial mechanism. Am J Cardiovasc Drugs. 2008;8(6):373-418.
    • (2008) Am J Cardiovasc Drugs. , vol.8 , Issue.6 , pp. 373-418
    • Golomb, B.A.1    Evans, M.A.2
  • 25
    • 84927742065 scopus 로고    scopus 로고
    • Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on assessment, aetiology and management
    • Stroes ES, Thompson PD, Corsini A, et al. Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on assessment, aetiology and management. Eur Heart J. 2015;36(17): 1012-1022.
    • (2015) Eur Heart J. , vol.36 , Issue.17 , pp. 1012-1022
    • Stroes, E.S.1    Thompson, P.D.2    Corsini, A.3
  • 26
    • 0035807113 scopus 로고    scopus 로고
    • Bayer pulls cerivastatin (Baycol) from market
    • Wooltorton E. Bayer pulls cerivastatin (Baycol) from market. CMAJ. 2001; 165(5):632.
    • (2001) CMAJ. , vol.165 , Issue.5 , pp. 632
    • Wooltorton, E.1
  • 27
    • 79960864934 scopus 로고    scopus 로고
    • Weighing the benefits of high-dose simvastatin against the risk of myopathy
    • Egan A, Colman E. Weighing the benefits of high-dose simvastatin against the risk of myopathy. N Engl J Med. 2011;365(4):285-287.
    • (2011) N Engl J Med. , vol.365 , Issue.4 , pp. 285-287
    • Egan, A.1    Colman, E.2
  • 28
    • 84933524872 scopus 로고    scopus 로고
    • Statin use and risk of diabetes mellitus
    • Chogtu B, Magazine R, Bairy KL. Statin use and risk of diabetes mellitus. World J Diabetes. 2015;6(2):352-357.
    • (2015) World J Diabetes. , vol.6 , Issue.2 , pp. 352-357
    • Chogtu, B.1    Magazine, R.2    Bairy, K.L.3
  • 29
    • 34249864128 scopus 로고    scopus 로고
    • Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial
    • Look ARG, Pi-Sunyer X, Blackburn G, et al. Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial. Diabetes Care. 2007;30(6):1374-1383.
    • (2007) Diabetes Care. , vol.30 , Issue.6 , pp. 1374-1383
    • Look, A.R.G.1    Pi-Sunyer, X.2    Blackburn, G.3
  • 31
    • 84881329514 scopus 로고    scopus 로고
    • Statin therapy and new-onset diabetes: molecular mechanisms and clinical relevance
    • Banach M, Malodobra-Mazur M, Gluba A, Katsiki N, Rysz J, Dobrzyn A. Statin therapy and new-onset diabetes: molecular mechanisms and clinical relevance. Curr Pharm Des. 2013;19(27):4904-4912.
    • (2013) Curr Pharm Des. , vol.19 , Issue.27 , pp. 4904-4912
    • Banach, M.1    Malodobra-Mazur, M.2    Gluba, A.3    Katsiki, N.4    Rysz, J.5    Dobrzyn, A.6
  • 32
    • 84878773567 scopus 로고    scopus 로고
    • Risk of incident diabetes among patients treated with statins: population based study
    • Carter AA, Gomes T, Camacho X, Juurlink DN, Shah BR, Mamdani MM. Risk of incident diabetes among patients treated with statins: population based study. BMJ. 2013;346:f2610.
    • (2013) BMJ. , vol.346
    • Carter, A.A.1    Gomes, T.2    Camacho, X.3    Juurlink, D.N.4    Shah, B.R.5    Mamdani, M.M.6
  • 33
    • 84868091600 scopus 로고    scopus 로고
    • Statins and risk of new-onset diabetes mellitus
    • Shah RV, Goldfine AB. Statins and risk of new-onset diabetes mellitus. Circulation. 2012;126(18):e282-e284.
    • (2012) Circulation. , vol.126 , Issue.18 , pp. 282-284
    • Shah, R.V.1    Goldfine, A.B.2
  • 34
    • 56749106312 scopus 로고    scopus 로고
    • Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
    • Ridker PM, Danielson E, Fonseca FA, et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med. 2008; 359(21):2195-2207.
    • (2008) N Engl J Med. , vol.359 , Issue.21 , pp. 2195-2207
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3
  • 36
    • 79959428660 scopus 로고    scopus 로고
    • Risk of incident diabetes with intensivedose compared with moderate-dose statin therapy: a meta-analysis
    • Preiss D, Seshasai SR, Welsh P, et al. Risk of incident diabetes with intensivedose compared with moderate-dose statin therapy: a meta-analysis. JAMA. 2011; 305(24):2556-2564.
    • (2011) JAMA. , vol.305 , Issue.24 , pp. 2556-2564
    • Preiss, D.1    Seshasai, S.R.2    Welsh, P.3
  • 37
    • 84955445737 scopus 로고    scopus 로고
    • Statins and its hepatic effects: newer data, implications, and changing recommendations
    • Jose J. Statins and its hepatic effects: newer data, implications, and changing recommendations. J Pharm Bioallied Sci. 2016;8(1):23-28.
    • (2016) J Pharm Bioallied Sci. , vol.8 , Issue.1 , pp. 23-28
    • Jose, J.1
  • 38
    • 84904698842 scopus 로고    scopus 로고
    • Spectrum of statin hepatotoxicity: experience of the drug-induced liver injury network
    • Russo MW, Hoofnagle JH, Gu J, et al. Spectrum of statin hepatotoxicity: experience of the drug-induced liver injury network. Hepatology. 2014;60(2): 679-686.
    • (2014) Hepatology. , vol.60 , Issue.2 , pp. 679-686
    • Russo, M.W.1    Hoofnagle, J.H.2    Gu, J.3
  • 40
    • 84881414412 scopus 로고    scopus 로고
    • Drug-drug interactions between HMG-CoA reductase inhibitors (statins) and antiviral protease inhibitors
    • Chauvin B, Drouot S, Barrail-Tran A, Taburet AM. Drug-drug interactions between HMG-CoA reductase inhibitors (statins) and antiviral protease inhibitors. Clin Pharmacokinet. 2013;52(10):815-831.
    • (2013) Clin Pharmacokinet. , vol.52 , Issue.10 , pp. 815-831
    • Chauvin, B.1    Drouot, S.2    Barrail-Tran, A.3    Taburet, A.M.4
  • 42
    • 84866131000 scopus 로고    scopus 로고
    • Lipid-lowering effect of fluvastatin in relation to cytochrome P450 2C9 variant alleles frequently distributed in the Czech population
    • Buzkova H, Pechandova K, Danzig V, et al. Lipid-lowering effect of fluvastatin in relation to cytochrome P450 2C9 variant alleles frequently distributed in the Czech population. Med Sci Monit. 2012;18(8):CR512-CR517.
    • (2012) Med Sci Monit. , vol.18 , Issue.8 , pp. 512-517
    • Buzkova, H.1    Pechandova, K.2    Danzig, V.3
  • 43
    • 81055140354 scopus 로고    scopus 로고
    • Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study
    • Elens L, Becker ML, Haufroid V, et al. Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study. Pharmacogenet Genomics. 2011;21(12):861-866.
    • (2011) Pharmacogenet Genomics. , vol.21 , Issue.12 , pp. 861-866
    • Elens, L.1    Becker, M.L.2    Haufroid, V.3
  • 44
    • 79960633918 scopus 로고    scopus 로고
    • Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs
    • Wang D, Guo Y, Wrighton SA, Cooke GE, Sadee W. Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs. Pharmacogenomics J. 2011;11(4):274-286.
    • (2011) Pharmacogenomics J. , vol.11 , Issue.4 , pp. 274-286
    • Wang, D.1    Guo, Y.2    Wrighton, S.A.3    Cooke, G.E.4    Sadee, W.5
  • 45
    • 84907968532 scopus 로고    scopus 로고
    • Creatine kinase elevation caused by a combination of fluvastatin and telmisartan in a patient heterozygous for the CYP2C93 and ABCC2-24C
    • Meyer zu Schwabedissen HE, Siegmund W, Kroemer HK, Rollnik JD. Creatine kinase elevation caused by a combination of fluvastatin and telmisartan in a patient heterozygous for the CYP2C93 and ABCC2-24C. T variants: a case report. BMC Res Notes. 2014;7:688.
    • (2014) T variants: a case report. BMC Res Notes. , vol.7 , pp. 688
    • Meyer zu Schwabedissen, H.E.1    Siegmund, W.2    Kroemer, H.K.3    Rollnik, J.D.4
  • 46
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy-a genomewide study
    • Group SC, Link E, Parish S, et al. SLCO1B1 variants and statin-induced myopathy-a genomewide study. N Engl J Med. 2008;359(8):789-799.
    • (2008) N Engl J Med. , vol.359 , Issue.8 , pp. 789-799
    • Group, S.C.1    Link, E.2    Parish, S.3
  • 47
    • 84884507686 scopus 로고    scopus 로고
    • Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentrations in routine clinical care
    • DeGorter MK, Tirona RG, Schwarz UI, et al. Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentrations in routine clinical care. Circ Cardiovasc Genet. 2013;6(4):400-408.
    • (2013) Circ Cardiovasc Genet. , vol.6 , Issue.4 , pp. 400-408
    • DeGorter, M.K.1    Tirona, R.G.2    Schwarz, U.I.3
  • 48
    • 84887338132 scopus 로고    scopus 로고
    • Drug interactions with statins
    • Causevic-Ramosevac A, Semiz S. Drug interactions with statins. Acta Pharm. 2013;63(3):277-293.
    • (2013) Acta Pharm. , vol.63 , Issue.3 , pp. 277-293
    • Causevic-Ramosevac, A.1    Semiz, S.2
  • 49
    • 84874778743 scopus 로고    scopus 로고
    • Grapefruit-medication interactions: forbidden fruit or avoidable consequences?
    • Bailey DG, Dresser G, Arnold JM. Grapefruit-medication interactions: forbidden fruit or avoidable consequences? CMAJ. 2013;185(4):309-316.
    • (2013) CMAJ. , vol.185 , Issue.4 , pp. 309-316
    • Bailey, D.G.1    Dresser, G.2    Arnold, J.M.3
  • 50
    • 3142523464 scopus 로고    scopus 로고
    • Effects of regular consumption of grapefruit juice on the pharmacokinetics of simvastatin
    • Lilja JJ, Neuvonen M, Neuvonen PJ. Effects of regular consumption of grapefruit juice on the pharmacokinetics of simvastatin. Br J Clin Pharmacol. 2004;58(1): 56-60.
    • (2004) Br J Clin Pharmacol. , vol.58 , Issue.1 , pp. 56-60
    • Lilja, J.J.1    Neuvonen, M.2    Neuvonen, P.J.3
  • 51
    • 1342330817 scopus 로고    scopus 로고
    • Statin-associated rhabdomyolysis triggered by grapefruit consumption
    • Dreier JP, Endres M. Statin-associated rhabdomyolysis triggered by grapefruit consumption. Neurology. 2004;62(4):670.
    • (2004) Neurology. , vol.62 , Issue.4 , pp. 670
    • Dreier, J.P.1    Endres, M.2
  • 52
    • 79951867093 scopus 로고    scopus 로고
    • Rhabdomyolysis in a prostate cancer patient taking ketoconazole and simvastatin: case report and review of the literature
    • Watkins JL, Atkinson BJ, Pagliaro LC. Rhabdomyolysis in a prostate cancer patient taking ketoconazole and simvastatin: case report and review of the literature. Ann Pharmacother. 2011;45(2):e9.
    • (2011) Ann Pharmacother. , vol.45 , Issue.2
    • Watkins, J.L.1    Atkinson, B.J.2    Pagliaro, L.C.3
  • 53
    • 80051810218 scopus 로고    scopus 로고
    • Rhabdomyolysis-induced acute renal failure due to itraconazole and simvastatin association
    • Roques S, Lytrivi M, Rusu D, Devriendt J, De Bels D. Rhabdomyolysis-induced acute renal failure due to itraconazole and simvastatin association. Drug Metabol Drug Interact. 2011;26(2):79-80.
    • (2011) Drug Metabol Drug Interact. , vol.26 , Issue.2 , pp. 79-80
    • Roques, S.1    Lytrivi, M.2    Rusu, D.3    Devriendt, J.4    De Bels, D.5
  • 54
    • 79960961358 scopus 로고    scopus 로고
    • Concomitant use of simvastatin and amiodarone resulting in severe rhabdomyolysis: a case report and review of the literature
    • Marot A, Morelle J, Chouinard VA, Jadoul M, Lambert M, Demoulin N. Concomitant use of simvastatin and amiodarone resulting in severe rhabdomyolysis: a case report and review of the literature. Acta Clin Belg. 2011;66(2):134-136.
    • (2011) Acta Clin Belg. , vol.66 , Issue.2 , pp. 134-136
    • Marot, A.1    Morelle, J.2    Chouinard, V.A.3    Jadoul, M.4    Lambert, M.5    Demoulin, N.6
  • 55
    • 33646241551 scopus 로고    scopus 로고
    • Simvastatin-amiodarone interaction resulting in rhabdomyolysis, azotemia, and possible hepatotoxicity
    • Ricaurte B, Guirguis A, Taylor HC, Zabriskie D. Simvastatin-amiodarone interaction resulting in rhabdomyolysis, azotemia, and possible hepatotoxicity. Ann Pharmacother. 2006;40(4):753-757.
    • (2006) Ann Pharmacother. , vol.40 , Issue.4 , pp. 753-757
    • Ricaurte, B.1    Guirguis, A.2    Taylor, H.C.3    Zabriskie, D.4
  • 56
    • 84880317056 scopus 로고    scopus 로고
    • Rhabdomyolysis and acute kidney injury secondary to interaction between simvastatin and cyclosporine
    • Scarfia RV, Clementi A, Granata A. Rhabdomyolysis and acute kidney injury secondary to interaction between simvastatin and cyclosporine. Ren Fail. 2013; 35(7):1056-1057.
    • (2013) Ren Fail. , vol.35 , Issue.7 , pp. 1056-1057
    • Scarfia, R.V.1    Clementi, A.2    Granata, A.3
  • 57
    • 34548321209 scopus 로고    scopus 로고
    • Simvastatin-induced rhabdomyolysis following cyclosporine treatment for uveitis
    • Lasocki A, Vote B, Fassett R, Zamir E. Simvastatin-induced rhabdomyolysis following cyclosporine treatment for uveitis. Ocul Immunol Inflamm. 2007;15(4): 345-346.
    • (2007) Ocul Immunol Inflamm. , vol.15 , Issue.4 , pp. 345-346
    • Lasocki, A.1    Vote, B.2    Fassett, R.3    Zamir, E.4
  • 58
    • 70350048926 scopus 로고    scopus 로고
    • Impact of OATP transporters on pharmacokinetics
    • Kalliokoski A, Niemi M. Impact of OATP transporters on pharmacokinetics. Br J Pharmacol. 2009;158(3):693-705.
    • (2009) Br J Pharmacol. , vol.158 , Issue.3 , pp. 693-705
    • Kalliokoski, A.1    Niemi, M.2
  • 60
    • 0345708294 scopus 로고    scopus 로고
    • Comparison of the efficacy of rosuvastatin versus atorvastatin, simvastatin, and pravastatin in achieving lipid goals: results from the STELLAR trial
    • McKenney JM, Jones PH, Adamczyk MA, et al. Comparison of the efficacy of rosuvastatin versus atorvastatin, simvastatin, and pravastatin in achieving lipid goals: results from the STELLAR trial. Curr Med Res Opin. 2003;19(8):689-698.
    • (2003) Curr Med Res Opin. , vol.19 , Issue.8 , pp. 689-698
    • McKenney, J.M.1    Jones, P.H.2    Adamczyk, M.A.3
  • 61
    • 84884474355 scopus 로고    scopus 로고
    • Comparative tolerability and harms of individual statins: a study-level network meta-analysis of 246 955 participants from 135 randomized, controlled trials
    • Naci H, Brugts J, Ades T. Comparative tolerability and harms of individual statins: a study-level network meta-analysis of 246 955 participants from 135 randomized, controlled trials. Circ Cardiovasc Qual Outcomes. 2013;6(4): 390-399.
    • (2013) Circ Cardiovasc Qual Outcomes. , vol.6 , Issue.4 , pp. 390-399
    • Naci, H.1    Brugts, J.2    Ades, T.3
  • 62
    • 84960834625 scopus 로고    scopus 로고
    • A VOYAGER meta-analysis of the impact of statin therapy on low-density lipoprotein cholesterol and triglyceride levels in patients with hypertriglyceridemia
    • Karlson BW, Palmer MK, Nicholls SJ, Lundman P, Barter PJ. A VOYAGER meta-analysis of the impact of statin therapy on low-density lipoprotein cholesterol and triglyceride levels in patients with hypertriglyceridemia. Am J Cardiol. 2016;117(9):1444-1448.
    • (2016) Am J Cardiol. , vol.117 , Issue.9 , pp. 1444-1448
    • Karlson, B.W.1    Palmer, M.K.2    Nicholls, S.J.3    Lundman, P.4    Barter, P.J.5
  • 63
    • 84865197598 scopus 로고    scopus 로고
    • A survey of the FDA's AERS database regarding muscle and tendon adverse events linked to the statin drug class
    • Hoffman KB, Kraus C, Dimbil M, Golomb BA. A survey of the FDA's AERS database regarding muscle and tendon adverse events linked to the statin drug class. PLoS One. 2012;7(8):e42866.
    • (2012) PLoS One. , vol.7 , Issue.8
    • Hoffman, K.B.1    Kraus, C.2    Dimbil, M.3    Golomb, B.A.4
  • 64
    • 32444444724 scopus 로고    scopus 로고
    • Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients-the PRIMO study
    • Bruckert E, Hayem G, Dejager S, Yau C, Begaud B. Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients-the PRIMO study. Cardiovasc Drugs Ther. 2005;19(6):403-414.
    • (2005) Cardiovasc Drugs Ther. , vol.19 , Issue.6 , pp. 403-414
    • Bruckert, E.1    Hayem, G.2    Dejager, S.3    Yau, C.4    Begaud, B.5
  • 65
    • 84872093145 scopus 로고    scopus 로고
    • Effect of statins on skeletal muscle function
    • Parker BA, Capizzi JA, Grimaldi AS, et al. Effect of statins on skeletal muscle function. Circulation. 2013;127(1):96-103.
    • (2013) Circulation. , vol.127 , Issue.1 , pp. 96-103
    • Parker, B.A.1    Capizzi, J.A.2    Grimaldi, A.S.3
  • 68
    • 0342981862 scopus 로고    scopus 로고
    • The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
    • Sacks FM, Pfeffer MA, Moye LA, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators. N Engl J Med. 1996; 335(14):1001-1009.
    • (1996) Cholesterol and Recurrent Events Trial investigators. N Engl J Med. , vol.335 , Issue.14 , pp. 1001-1009
    • Sacks, F.M.1    Pfeffer, M.A.2    Moye, L.A.3
  • 69
    • 33646354412 scopus 로고    scopus 로고
    • Statin therapy and autoimmune disease: from protein prenylation to immunomodulation
    • Greenwood J, Steinman L, Zamvil SS. Statin therapy and autoimmune disease: from protein prenylation to immunomodulation. Nat Rev Immunol. 2006;6(5): 358-370.
    • (2006) Nat Rev Immunol. , vol.6 , Issue.5 , pp. 358-370
    • Greenwood, J.1    Steinman, L.2    Zamvil, S.S.3
  • 70
    • 84906789715 scopus 로고    scopus 로고
    • Statins: from cholesterol-lowering drugs to novel immunomodulators for the treatment of Th17-mediated autoimmune diseases
    • Ulivieri C, Baldari CT. Statins: from cholesterol-lowering drugs to novel immunomodulators for the treatment of Th17-mediated autoimmune diseases. Pharmacol Res. 2014;88:41-52.
    • (2014) Pharmacol Res. , vol.88 , pp. 41-52
    • Ulivieri, C.1    Baldari, C.T.2
  • 73
    • 0034948339 scopus 로고    scopus 로고
    • Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site
    • Weitz-Schmidt G, Welzenbach K, Brinkmann V, et al. Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site. Nat Med. 2001;7(6):687-692.
    • (2001) Nat Med. , vol.7 , Issue.6 , pp. 687-692
    • Weitz-Schmidt, G.1    Welzenbach, K.2    Brinkmann, V.3
  • 74
    • 84886547277 scopus 로고    scopus 로고
    • Statins as modulators of regulatory T-cell biology
    • Forero-Pena DA, Gutierrez FR. Statins as modulators of regulatory T-cell biology. Mediators Inflamm. 2013;2013:167086.
    • (2013) Mediators Inflamm. , vol.2013 , pp. 167086
    • Forero-Pena, D.A.1    Gutierrez, F.R.2
  • 75
    • 0037038402 scopus 로고    scopus 로고
    • The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease
    • Youssef S, Stuve O, Patarroyo JC, et al. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature. 2002;420(6911):78-84.
    • (2002) Nature. , vol.420 , Issue.6911 , pp. 78-84
    • Youssef, S.1    Stuve, O.2    Patarroyo, J.C.3
  • 76
    • 84943198862 scopus 로고    scopus 로고
    • Inflammatory bowel disease: an archetype disorder of outer environment sensor systems
    • Actis GC, Rosina F. Inflammatory bowel disease: an archetype disorder of outer environment sensor systems. World J Gastrointest Pharmacol Ther. 2013;4(3): 41-46.
    • (2013) World J Gastrointest Pharmacol Ther. , vol.4 , Issue.3 , pp. 41-46
    • Actis, G.C.1    Rosina, F.2
  • 77
    • 84894487816 scopus 로고    scopus 로고
    • Statins as regulators of redox state in the vascular endothelium: beyond lipid lowering
    • Margaritis M, Channon KM, Antoniades C. Statins as regulators of redox state in the vascular endothelium: beyond lipid lowering. Antioxid Redox Signal. 2014;20(8):1198-1215.
    • (2014) Antioxid Redox Signal. , vol.20 , Issue.8 , pp. 1198-1215
    • Margaritis, M.1    Channon, K.M.2    Antoniades, C.3
  • 78
    • 84896542936 scopus 로고    scopus 로고
    • Th17 and regulatory T cell balance in autoimmune and inflammatory diseases
    • Noack M, Miossec P. Th17 and regulatory T cell balance in autoimmune and inflammatory diseases. Autoimmun Rev. 2014;13(6):668-677.
    • (2014) Autoimmun Rev. , vol.13 , Issue.6 , pp. 668-677
    • Noack, M.1    Miossec, P.2
  • 79
    • 84872130535 scopus 로고    scopus 로고
    • Anti-inflammatory therapy in chronic disease: challenges and opportunities
    • Tabas I, Glass CK. Anti-inflammatory therapy in chronic disease: challenges and opportunities. Science. 2013;339(6116):166-172.
    • (2013) Science. , vol.339 , Issue.6116 , pp. 166-172
    • Tabas, I.1    Glass, C.K.2
  • 80
    • 84907598207 scopus 로고    scopus 로고
    • Role of statins in the treatment of multiple sclerosis
    • Ciurleo R, Bramanti P, Marino S. Role of statins in the treatment of multiple sclerosis. Pharmacol Res. 2014;87:133-143.
    • (2014) Pharmacol Res. , vol.87 , pp. 133-143
    • Ciurleo, R.1    Bramanti, P.2    Marino, S.3
  • 81
    • 84985946870 scopus 로고    scopus 로고
    • Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis
    • Martin R, Sospedra M, Rosito M, Engelhardt B. Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis. Eur J Immunol. 2016;46:2078-2090.
    • (2016) Eur J Immunol. , vol.46 , pp. 2078-2090
    • Martin, R.1    Sospedra, M.2    Rosito, M.3    Engelhardt, B.4
  • 82
    • 84903318797 scopus 로고    scopus 로고
    • Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MSSTAT): a randomised, placebo-controlled, phase 2 trial
    • Chataway J, Schuerer N, Alsanousi A, et al. Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MSSTAT): a randomised, placebo-controlled, phase 2 trial. Lancet. 2014;383(9936): 2213-2221.
    • (2014) Lancet. , vol.383 , Issue.9936 , pp. 2213-2221
    • Chataway, J.1    Schuerer, N.2    Alsanousi, A.3
  • 83
    • 77954688218 scopus 로고    scopus 로고
    • Atorvastatin combined to interferon to verify the efficacy (ACTIVE) in relapsing-remitting active multiple sclerosis patients: a longitudinal controlled trial of combination therapy
    • Lanzillo R, Orefice G, Quarantelli M, et al. Atorvastatin combined to interferon to verify the efficacy (ACTIVE) in relapsing-remitting active multiple sclerosis patients: a longitudinal controlled trial of combination therapy. Mult Scler. 2010;16(4):450-454.
    • (2010) Mult Scler. , vol.16 , Issue.4 , pp. 450-454
    • Lanzillo, R.1    Orefice, G.2    Quarantelli, M.3
  • 84
    • 79960341237 scopus 로고    scopus 로고
    • Simvastatin as add-on therapy to interferon beta-1a for relapsing-remitting multiple sclerosis (SIMCOMBIN study): a placebo-controlled randomised phase 4 trial
    • Sorensen PS, Lycke J, Eralinna JP, et al. Simvastatin as add-on therapy to interferon beta-1a for relapsing-remitting multiple sclerosis (SIMCOMBIN study): a placebo-controlled randomised phase 4 trial. Lancet Neurol. 2011;10(8): 691-701.
    • (2011) Lancet Neurol. , vol.10 , Issue.8 , pp. 691-701
    • Sorensen, P.S.1    Lycke, J.2    Eralinna, J.P.3
  • 85
    • 84912575574 scopus 로고    scopus 로고
    • Atorvastatin calcium in combination with methylprednisolone for the treatment of multiple sclerosis relapse
    • Li XL, Zhang ZC, Zhang B, et al. Atorvastatin calcium in combination with methylprednisolone for the treatment of multiple sclerosis relapse. Int Immunopharmacol. 2014;23(2):546-549.
    • (2014) Int Immunopharmacol. , vol.23 , Issue.2 , pp. 546-549
    • Li, X.L.1    Zhang, Z.C.2    Zhang, B.3
  • 86
    • 77955023091 scopus 로고    scopus 로고
    • Simvastatin treatment in patients with relapsing-remitting multiple sclerosis receiving interferon beta 1a: a double-blind randomized controlled trial
    • Togha M, Karvigh SA, Nabavi M, et al. Simvastatin treatment in patients with relapsing-remitting multiple sclerosis receiving interferon beta 1a: a double-blind randomized controlled trial. Mult Scler. 2010;16(7):848-854.
    • (2010) Mult Scler. , vol.16 , Issue.7 , pp. 848-854
    • Togha, M.1    Karvigh, S.A.2    Nabavi, M.3
  • 87
    • 84868195949 scopus 로고    scopus 로고
    • Atorvastatin added to interferon beta for relapsing multiple sclerosis: a randomized controlled trial
    • Kamm CP, El-Koussy M, Humpert S, et al. Atorvastatin added to interferon beta for relapsing multiple sclerosis: a randomized controlled trial. J Neurol. 2012;259(11):2401-2413.
    • (2012) J Neurol. , vol.259 , Issue.11 , pp. 2401-2413
    • Kamm, C.P.1    El-Koussy, M.2    Humpert, S.3
  • 88
    • 84939933682 scopus 로고    scopus 로고
    • Statin treatment in multiple sclerosis: a systematic review and meta-analysis
    • Pihl-Jensen G, Tsakiri A, Frederiksen JL. Statin treatment in multiple sclerosis: a systematic review and meta-analysis. CNS Drugs. 2015;29(4):277-291.
    • (2015) CNS Drugs. , vol.29 , Issue.4 , pp. 277-291
    • Pihl-Jensen, G.1    Tsakiri, A.2    Frederiksen, J.L.3
  • 89
    • 84951919076 scopus 로고    scopus 로고
    • Immunopathogenesis of IBD: current state of the art
    • de Souza HS, Fiocchi C. Immunopathogenesis of IBD: current state of the art. Nat Rev Gastroenterol Hepatol. 2016;13(1):13-27.
    • (2016) Nat Rev Gastroenterol Hepatol. , vol.13 , Issue.1 , pp. 13-27
    • de Souza, H.S.1    Fiocchi, C.2
  • 92
    • 84860672665 scopus 로고    scopus 로고
    • Statins are associated with reduced use of steroids in inflammatory bowel disease: a retrospective cohort study
    • Crockett SD, Hansen RA, Sturmer T, et al. Statins are associated with reduced use of steroids in inflammatory bowel disease: a retrospective cohort study. Inflamm Bowel Dis. 2012;18(6):1048-1056.
    • (2012) Inflamm Bowel Dis. , vol.18 , Issue.6 , pp. 1048-1056
    • Crockett, S.D.1    Hansen, R.A.2    Sturmer, T.3
  • 93
    • 56749161704 scopus 로고    scopus 로고
    • Use of atorvastatin as an anti-inflammatory treatment in Crohn's disease
    • Grip O, Janciauskiene S, Bredberg A. Use of atorvastatin as an anti-inflammatory treatment in Crohn's disease. Br J Pharmacol. 2008;155(7):1085-1092.
    • (2008) Br J Pharmacol. , vol.155 , Issue.7 , pp. 1085-1092
    • Grip, O.1    Janciauskiene, S.2    Bredberg, A.3
  • 94
    • 65549131046 scopus 로고    scopus 로고
    • Atorvastatin reduces plasma levels of chemokine (CXCL10) in patients with Crohn's disease
    • Grip O, Janciauskiene S. Atorvastatin reduces plasma levels of chemokine (CXCL10) in patients with Crohn's disease. PLoS One. 2009;4(5):e5263.
    • (2009) PLoS One. , vol.4 , Issue.5
    • Grip, O.1    Janciauskiene, S.2
  • 96
    • 84965178992 scopus 로고    scopus 로고
    • Cardiovascular risk in rheumatoid arthritis: assessment, management and next steps
    • Zegkos T, Kitas G, Dimitroulas T. Cardiovascular risk in rheumatoid arthritis: assessment, management and next steps. Ther Adv Musculoskelet Dis. 2016;8(3): 86-101.
    • (2016) Ther Adv Musculoskelet Dis. , vol.8 , Issue.3 , pp. 86-101
    • Zegkos, T.1    Kitas, G.2    Dimitroulas, T.3
  • 98
    • 84928609082 scopus 로고    scopus 로고
    • The impact of statins therapy on disease activity and inflammatory factor in patients with rheumatoid arthritis: a meta-analysis
    • Lv S, Liu Y, Zou Z, et al. The impact of statins therapy on disease activity and inflammatory factor in patients with rheumatoid arthritis: a meta-analysis. Clin Exp Rheumatol. 2015;33(1):69-76.
    • (2015) Clin Exp Rheumatol. , vol.33 , Issue.1 , pp. 69-76
    • Lv, S.1    Liu, Y.2    Zou, Z.3
  • 99
    • 84992648197 scopus 로고    scopus 로고
    • Statins and risk of rheumatoid arthritis-a nested case-control study
    • [Epub ahead of print].
    • Tascilar K, Dell'Aniello S, Hudson M, Suissa S. Statins and risk of rheumatoid arthritis-a nested case-control study. Arthritis Rheumatol. 2016. [Epub ahead of print].
    • (2016) Arthritis Rheumatol
    • Tascilar, K.1    Dell'Aniello, S.2    Hudson, M.3    Suissa, S.4
  • 100
    • 84967268209 scopus 로고    scopus 로고
    • Effect of atorvastatin on the disease activity and severity of rheumatoid arthritis: double-blind randomized controlled trial
    • Mowla K, Rajai E, Ghorbani A, Dargahi-Malamir M, Bahadoram M, Mohammadi S. Effect of atorvastatin on the disease activity and severity of rheumatoid arthritis: double-blind randomized controlled trial. J Clin Diagn Res. 2016;10(5):OC32-OC36.
    • (2016) J Clin Diagn Res. , vol.10 , Issue.5 , pp. 32-36
    • Mowla, K.1    Rajai, E.2    Ghorbani, A.3    Dargahi-Malamir, M.4    Bahadoram, M.5    Mohammadi, S.6
  • 101
    • 84925451300 scopus 로고    scopus 로고
    • The antiinflammatory properties of simvastatin can benefit statin-naive rheumatoid arthritis patients with associated risks for cardiovascular disease
    • Komolafe AO, Ally MMTM, Van Tonder JJ, Greeff OBW. The antiinflammatory properties of simvastatin can benefit statin-naive rheumatoid arthritis patients with associated risks for cardiovascular disease. S Afr Fam Pract. 2015;57(1):28-30.
    • (2015) S Afr Fam Pract. , vol.57 , Issue.1 , pp. 28-30
    • Komolafe, A.O.1    Ally, M.M.T.M.2    Van Tonder, J.J.3    Greeff, O.B.W.4
  • 103
    • 84877821946 scopus 로고    scopus 로고
    • Emerging and critical issues in the pathogenesis of lupus
    • Gatto M, Zen M, Ghirardello A, et al. Emerging and critical issues in the pathogenesis of lupus. Autoimmun Rev. 2013;12(4):523-536.
    • (2013) Autoimmun Rev. , vol.12 , Issue.4 , pp. 523-536
    • Gatto, M.1    Zen, M.2    Ghirardello, A.3
  • 104
    • 84969963435 scopus 로고    scopus 로고
    • Update on cardiovascular disease in lupus
    • Lewandowski LB, Kaplan MJ. Update on cardiovascular disease in lupus. Curr Opin Rheumatol. 2016;28(5):468-476.
    • (2016) Curr Opin Rheumatol. , vol.28 , Issue.5 , pp. 468-476
    • Lewandowski, L.B.1    Kaplan, M.J.2
  • 105
    • 84959098170 scopus 로고    scopus 로고
    • Statin impact on disease activity and C-reactive protein concentrations in systemic lupus erythematosus patients: a systematic review and meta-analysis of controlled trials
    • Sahebkar A, Rathouska J, Derosa G, Maffioli P, Nachtigal P. Statin impact on disease activity and C-reactive protein concentrations in systemic lupus erythematosus patients: a systematic review and meta-analysis of controlled trials. Autoimmun Rev. 2016;15(4):344-353.
    • (2016) Autoimmun Rev. , vol.15 , Issue.4 , pp. 344-353
    • Sahebkar, A.1    Rathouska, J.2    Derosa, G.3    Maffioli, P.4    Nachtigal, P.5
  • 106
    • 84940785004 scopus 로고    scopus 로고
    • Statin reduces mortality and morbidity in systemic lupus erythematosus patients with hyperlipidemia: a nationwide population-based cohort study
    • Yu HH, Chen PC, Yang YH, et al. Statin reduces mortality and morbidity in systemic lupus erythematosus patients with hyperlipidemia: a nationwide population-based cohort study. Atherosclerosis. 2015;243(1):11-18.
    • (2015) Atherosclerosis. , vol.243 , Issue.1 , pp. 11-18
    • Yu, H.H.1    Chen, P.C.2    Yang, Y.H.3
  • 107
    • 33845629866 scopus 로고    scopus 로고
    • Lupus erythematosus and other autoimmune diseases related to statin therapy: a systematic review
    • Noel B. Lupus erythematosus and other autoimmune diseases related to statin therapy: a systematic review. J Eur Acad Dermatol Venereol. 2007;21(1):17-24.
    • (2007) J Eur Acad Dermatol Venereol. , vol.21 , Issue.1 , pp. 17-24
    • Noel, B.1
  • 108
    • 84904251017 scopus 로고    scopus 로고
    • Statins as a potential risk factor for autoimmune diseases: a case report and review
    • John SG, Thorn J, Sobonya R. Statins as a potential risk factor for autoimmune diseases: a case report and review. Am J Ther. 2014;21(4):e94-e96.
    • (2014) Am J Ther. , vol.21 , Issue.4 , pp. 94-96
    • John, S.G.1    Thorn, J.2    Sobonya, R.3
  • 110
    • 84984890217 scopus 로고    scopus 로고
    • Prevention of acute exacerbations of COPD: American College of Chest Physicians and Canadian Thoracic Society Guideline
    • Criner GJ, Bourbeau J, Diekemper RL, et al. Prevention of acute exacerbations of COPD: American College of Chest Physicians and Canadian Thoracic Society Guideline. Chest. 2015;147(4):894-942.
    • (2015) Chest. , vol.147 , Issue.4 , pp. 894-942
    • Criner, G.J.1    Bourbeau, J.2    Diekemper, R.L.3
  • 111
    • 84901817055 scopus 로고    scopus 로고
    • Simvastatin for the prevention of exacerbations in moderate-to-severe COPD
    • Criner GJ, Connett JE, Aaron SD, et al. Simvastatin for the prevention of exacerbations in moderate-to-severe COPD. N Engl J Med. 2014;370(23):2201-2210.
    • (2014) N Engl J Med. , vol.370 , Issue.23 , pp. 2201-2210
    • Criner, G.J.1    Connett, J.E.2    Aaron, S.D.3
  • 112
    • 84930924025 scopus 로고    scopus 로고
    • Rosuvastatin treatment in stable chronic obstructive pulmonary disease (RODEO): a randomized controlled trial
    • Neukamm A, Hoiseth AD, Einvik G, et al. Rosuvastatin treatment in stable chronic obstructive pulmonary disease (RODEO): a randomized controlled trial. J Intern Med. 2015;278(1):59-67.
    • (2015) J Intern Med. , vol.278 , Issue.1 , pp. 59-67
    • Neukamm, A.1    Hoiseth, A.D.2    Einvik, G.3
  • 113
    • 19444364509 scopus 로고    scopus 로고
    • Statins and the risk of colorectal cancer
    • Poynter JN, Gruber SB, Higgins PD, et al. Statins and the risk of colorectal cancer. N Engl J Med. 2005;352(21):2184-2192.
    • (2005) N Engl J Med. , vol.352 , Issue.21 , pp. 2184-2192
    • Poynter, J.N.1    Gruber, S.B.2    Higgins, P.D.3
  • 114
    • 84868550230 scopus 로고    scopus 로고
    • Statin use and reduced cancer-related mortality
    • Nielsen SF, Nordestgaard BG, Bojesen SE. Statin use and reduced cancer-related mortality. N Engl J Med. 2012;367(19):1792-1802.
    • (2012) N Engl J Med. , vol.367 , Issue.19 , pp. 1792-1802
    • Nielsen, S.F.1    Nordestgaard, B.G.2    Bojesen, S.E.3
  • 116
    • 84894265324 scopus 로고    scopus 로고
    • Statins and the risk of colorectal cancer: an updated systematic review and meta-analysis of 40 studies
    • Lytras T, Nikolopoulos G, Bonovas S. Statins and the risk of colorectal cancer: an updated systematic review and meta-analysis of 40 studies. World J Gastroenterol. 2014;20(7):1858-1870.
    • (2014) World J Gastroenterol. , vol.20 , Issue.7 , pp. 1858-1870
    • Lytras, T.1    Nikolopoulos, G.2    Bonovas, S.3
  • 117
    • 84867641427 scopus 로고    scopus 로고
    • Statin use and association with colorectal cancer survival and risk: case control study with prescription data linkage
    • Lakha F, Theodoratou E, Farrington SM, et al. Statin use and association with colorectal cancer survival and risk: case control study with prescription data linkage. BMC Cancer. 2012;12:487.
    • (2012) BMC Cancer. , vol.12 , pp. 487
    • Lakha, F.1    Theodoratou, E.2    Farrington, S.M.3
  • 120
    • 79955761349 scopus 로고    scopus 로고
    • The associations between statin use and prostate cancer screening, prostate size, high-grade prostatic intraepithelial neoplasia (PIN), and prostate cancer
    • Fowke JH, Motley SS, Barocas DA, et al. The associations between statin use and prostate cancer screening, prostate size, high-grade prostatic intraepithelial neoplasia (PIN), and prostate cancer. Cancer Causes Control. 2011;22(3):417-426.
    • (2011) Cancer Causes Control. , vol.22 , Issue.3 , pp. 417-426
    • Fowke, J.H.1    Motley, S.S.2    Barocas, D.A.3
  • 121
    • 84925356385 scopus 로고    scopus 로고
    • The risk of prostate cancer for men on aspirin, statin or antidiabetic medications
    • Nordstrom T, Clements M, Karlsson R, Adolfsson J, Gronberg H. The risk of prostate cancer for men on aspirin, statin or antidiabetic medications. Eur J Cancer. 2015;51(6):725-733.
    • (2015) Eur J Cancer. , vol.51 , Issue.6 , pp. 725-733
    • Nordstrom, T.1    Clements, M.2    Karlsson, R.3    Adolfsson, J.4    Gronberg, H.5
  • 122
    • 77955875455 scopus 로고    scopus 로고
    • Prostate cancer and PSA among statin users in the Finnish prostate cancer screening trial
    • Murtola TJ, Tammela TL, Maattanen L, et al. Prostate cancer and PSA among statin users in the Finnish prostate cancer screening trial. Int J Cancer. 2010;127(7):1650-1659.
    • (2010) Int J Cancer. , vol.127 , Issue.7 , pp. 1650-1659
    • Murtola, T.J.1    Tammela, T.L.2    Maattanen, L.3
  • 123
    • 33845864688 scopus 로고    scopus 로고
    • Statin drugs and risk of advanced prostate cancer
    • Platz EA, Leitzmann MF, Visvanathan K, et al. Statin drugs and risk of advanced prostate cancer. J Natl Cancer Inst. 2006;98(24):1819-1825.
    • (2006) J Natl Cancer Inst. , vol.98 , Issue.24 , pp. 1819-1825
    • Platz, E.A.1    Leitzmann, M.F.2    Visvanathan, K.3
  • 124
    • 84894229646 scopus 로고    scopus 로고
    • Statin use and risk of prostate cancer: a Danish population-based case-control study, 1997-2010
    • Jespersen CG, Norgaard M, Friis S, Skriver C, Borre M. Statin use and risk of prostate cancer: a Danish population-based case-control study, 1997-2010. Cancer Epidemiol. 2014;38(1):42-47.
    • (2014) Cancer Epidemiol. , vol.38 , Issue.1 , pp. 42-47
    • Jespersen, C.G.1    Norgaard, M.2    Friis, S.3    Skriver, C.4    Borre, M.5
  • 125
    • 84947492288 scopus 로고    scopus 로고
    • A randomised, double-blind, placebocontrolled multi-centre phase III trial of XELIRI/FOLFIRI plus simvastatin for patients with metastatic colorectal cancer
    • Lim SH, Kim TW, Hong YS, et al. A randomised, double-blind, placebocontrolled multi-centre phase III trial of XELIRI/FOLFIRI plus simvastatin for patients with metastatic colorectal cancer. Br J Cancer. 2015;113(10):1421-1426.
    • (2015) Br J Cancer. , vol.113 , Issue.10 , pp. 1421-1426
    • Lim, S.H.1    Kim, T.W.2    Hong, Y.S.3
  • 126
    • 84947484398 scopus 로고    scopus 로고
    • Safety and efficacy of the addition of simvastatin to cetuximab in previously treated KRAS mutant metastatic colorectal cancer patients
    • Baas JM, Krens LL, ten Tije AJ, et al. Safety and efficacy of the addition of simvastatin to cetuximab in previously treated KRAS mutant metastatic colorectal cancer patients. Invest New Drugs. 2015;33(6):1242-1247.
    • (2015) Invest New Drugs. , vol.33 , Issue.6 , pp. 1242-1247
    • Baas, J.M.1    Krens, L.L.2    ten Tije, A.J.3
  • 127
    • 84884564996 scopus 로고    scopus 로고
    • Mortality and recurrence risk in relation to the use of lipid-lowering drugs in a prospective breast cancer patient cohort
    • Nickels S, Vrieling A, Seibold P, et al. Mortality and recurrence risk in relation to the use of lipid-lowering drugs in a prospective breast cancer patient cohort. PLoS One. 2013;8(9):e75088.
    • (2013) PLoS One. , vol.8 , Issue.9
    • Nickels, S.1    Vrieling, A.2    Seibold, P.3
  • 128
    • 84908192085 scopus 로고    scopus 로고
    • Statin use and breast cancer survival: a nationwide cohort study from Finland
    • Murtola TJ, Visvanathan K, Artama M, Vainio H, Pukkala E. Statin use and breast cancer survival: a nationwide cohort study from Finland. PLoS One. 2014; 9(10):e110231.
    • (2014) PLoS One. , vol.9 , Issue.10
    • Murtola, T.J.1    Visvanathan, K.2    Artama, M.3    Vainio, H.4    Pukkala, E.5
  • 129
    • 84891107346 scopus 로고    scopus 로고
    • Statin use may improve clinicopathological characteristics and recurrence risk of invasive breast cancer
    • Sendur MA, Aksoy S, Yazici O, Ozdemir NY, Zengin N, Altundag K. Statin use may improve clinicopathological characteristics and recurrence risk of invasive breast cancer. Med Oncol. 2014;31(2):835.
    • (2014) Med Oncol. , vol.31 , Issue.2 , pp. 835
    • Sendur, M.A.1    Aksoy, S.2    Yazici, O.3    Ozdemir, N.Y.4    Zengin, N.5    Altundag, K.6
  • 130
    • 80054078528 scopus 로고    scopus 로고
    • Statin prescriptions and breast cancer recurrence risk: a Danish nationwide prospective cohort study
    • Ahern TP, Pedersen L, Tarp M, et al. Statin prescriptions and breast cancer recurrence risk: a Danish nationwide prospective cohort study. J Natl Cancer Inst. 2011;103(19):1461-1468.
    • (2011) J Natl Cancer Inst. , vol.103 , Issue.19 , pp. 1461-1468
    • Ahern, T.P.1    Pedersen, L.2    Tarp, M.3
  • 131
    • 84982960859 scopus 로고    scopus 로고
    • Statin use at the time of initiation of androgen deprivation therapy and time to progression in patients with hormone-sensitive prostate cancer
    • Harshman LC, Wang X, Nakabayashi M, et al. Statin use at the time of initiation of androgen deprivation therapy and time to progression in patients with hormone-sensitive prostate cancer. JAMA Oncol. 2015;1(4):495-504.
    • (2015) JAMA Oncol. , vol.1 , Issue.4 , pp. 495-504
    • Harshman, L.C.1    Wang, X.2    Nakabayashi, M.3
  • 132
    • 84962385271 scopus 로고    scopus 로고
    • Statin use and prostate cancer aggressiveness: results from the population-based north carolina-louisiana prostate cancer project
    • Allott EH, Farnan L, Steck SE, et al. Statin use and prostate cancer aggressiveness: results from the population-based north carolina-louisiana prostate cancer project. Cancer Epidemiol Biomarkers Prev. 2016;25(4):670-677.
    • (2016) Cancer Epidemiol Biomarkers Prev. , vol.25 , Issue.4 , pp. 670-677
    • Allott, E.H.1    Farnan, L.2    Steck, S.E.3
  • 133
    • 84894664208 scopus 로고    scopus 로고
    • Use of statins and the risk of death in patients with prostate cancer
    • Yu O, Eberg M, Benayoun S, et al. Use of statins and the risk of death in patients with prostate cancer. J Clin Oncol. 2014;32(1):5-11.
    • (2014) J Clin Oncol. , vol.32 , Issue.1 , pp. 5-11
    • Yu, O.1    Eberg, M.2    Benayoun, S.3
  • 134
    • 84879421132 scopus 로고    scopus 로고
    • Statin use in relation to prostate cancer outcomes in a population-based patient cohort study
    • Geybels MS, Wright JL, Holt SK, Kolb S, Feng Z, Stanford JL. Statin use in relation to prostate cancer outcomes in a population-based patient cohort study. Prostate. 2013;73(11):1214-1222.
    • (2013) Prostate. , vol.73 , Issue.11 , pp. 1214-1222
    • Geybels, M.S.1    Wright, J.L.2    Holt, S.K.3    Kolb, S.4    Feng, Z.5    Stanford, J.L.6
  • 137
    • 84964796090 scopus 로고    scopus 로고
    • Disentangling the association between statins, cholesterol, and colorectal cancer: a nested case-control study
    • Mamtani R, Lewis JD, Scott FI, et al. Disentangling the association between statins, cholesterol, and colorectal cancer: a nested case-control study. PLoS Med. 2016;13(4):e1002007.
    • (2016) PLoS Med. , vol.13 , Issue.4
    • Mamtani, R.1    Lewis, J.D.2    Scott, F.I.3
  • 139
    • 84920944831 scopus 로고    scopus 로고
    • Colorectal cancer heterogeneity and targeted therapy: a case for molecular disease subtypes
    • Linnekamp JF, Wang X, Medema JP, Vermeulen L. Colorectal cancer heterogeneity and targeted therapy: a case for molecular disease subtypes. Cancer Res. 2015;75(2):245-249.
    • (2015) Cancer Res. , vol.75 , Issue.2 , pp. 245-249
    • Linnekamp, J.F.1    Wang, X.2    Medema, J.P.3    Vermeulen, L.4
  • 140
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-674.
    • (2011) Cell. , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 141
  • 144
    • 75149127674 scopus 로고    scopus 로고
    • Statins and breast cancer in postmenopausal women without hormone therapy
    • Eaton M, Eklof J, Beal JR, Sahmoun AE. Statins and breast cancer in postmenopausal women without hormone therapy. Anticancer Res. 2009;29(12):5143-5148.
    • (2009) Anticancer Res. , vol.29 , Issue.12 , pp. 5143-5148
    • Eaton, M.1    Eklof, J.2    Beal, J.R.3    Sahmoun, A.E.4
  • 146
    • 77950813460 scopus 로고    scopus 로고
    • Genetic variation in 3-hydroxy- 3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer
    • Lipkin SM, Chao EC, Moreno V, et al. Genetic variation in 3-hydroxy- 3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer. Cancer Prev Res (Phila). 2010;3(5):597-603.
    • (2010) Cancer Prev Res (Phila). , vol.3 , Issue.5 , pp. 597-603
    • Lipkin, S.M.1    Chao, E.C.2    Moreno, V.3
  • 148
    • 72449163475 scopus 로고    scopus 로고
    • Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer
    • Garwood ER, Kumar AS, Baehner FL, et al. Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer. Breast Cancer Res Treat. 2010;119(1):137-144.
    • (2010) Breast Cancer Res Treat. , vol.119 , Issue.1 , pp. 137-144
    • Garwood, E.R.1    Kumar, A.S.2    Baehner, F.L.3
  • 149
    • 84856235374 scopus 로고    scopus 로고
    • A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer
    • Higgins MJ, Prowell TM, Blackford AL, et al. A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer. Breast Cancer Res Treat. 2012;131(3):915-924.
    • (2012) Breast Cancer Res Treat. , vol.131 , Issue.3 , pp. 915-924
    • Higgins, M.J.1    Prowell, T.M.2    Blackford, A.L.3
  • 150
    • 84942895453 scopus 로고    scopus 로고
    • Global transcriptional changes following statin treatment in breast cancer
    • Bjarnadottir O, Kimbung S, Johansson I, et al. Global transcriptional changes following statin treatment in breast cancer. Clin Cancer Res. 2015;21(15):3402-3411.
    • (2015) Clin Cancer Res. , vol.21 , Issue.15 , pp. 3402-3411
    • Bjarnadottir, O.1    Kimbung, S.2    Johansson, I.3
  • 151
    • 85013393277 scopus 로고    scopus 로고
    • 2
    • What Is a Stroke. 2016. Available at: http://www.nhlbi.nih.gov/health/healthtopics/topics/stroke.
  • 153
    • 85013393267 scopus 로고    scopus 로고
    • Association between statin use and short-term outcome based on severity of ischemic stroke: a cohort study
    • PLoS One
    • Song B, Wang Y, Zhao X, et al. Association between statin use and short-term outcome based on severity of ischemic stroke: a cohort study. PLoS One.
    • Song, B.1    Wang, Y.2    Zhao, X.3
  • 155
    • 64349105221 scopus 로고    scopus 로고
    • Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention
    • Amarenco P, Labreuche J. Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention. Lancet Neurol. 2009;8(5):453-463.
    • (2009) Lancet Neurol. , vol.8 , Issue.5 , pp. 453-463
    • Amarenco, P.1    Labreuche, J.2
  • 156
    • 84855344320 scopus 로고    scopus 로고
    • Statin use during ischemic stroke hospitalization is strongly associated with improved poststroke survival
    • Flint AC, Kamel H, Navi BB, et al. Statin use during ischemic stroke hospitalization is strongly associated with improved poststroke survival. Stroke. 2012; 43(1):147-154.
    • (2012) Stroke. , vol.43 , Issue.1 , pp. 147-154
    • Flint, A.C.1    Kamel, H.2    Navi, B.B.3
  • 157
    • 79954598755 scopus 로고    scopus 로고
    • Statin use prior to ischemic stroke onset is associated with decreased in-hospital mortality
    • Hassan Y, Al-Jabi SW, Aziz NA, Looi I, Zyoud SH. Statin use prior to ischemic stroke onset is associated with decreased in-hospital mortality. Fundam Clin Pharmacol. 2011;25(3):388-394.
    • (2011) Fundam Clin Pharmacol. , vol.25 , Issue.3 , pp. 388-394
    • Hassan, Y.1    Al-Jabi, S.W.2    Aziz, N.A.3    Looi, I.4    Zyoud, S.H.5
  • 158
    • 21844470512 scopus 로고    scopus 로고
    • Statin administration prior to ischaemic stroke onset and survival: exploratory evidence from matched treatment-control study
    • Aslanyan S, Weir CJ, McInnes GT, Reid JL, Walters MR, Lees KR. Statin administration prior to ischaemic stroke onset and survival: exploratory evidence from matched treatment-control study. Eur J Neurol. 2005;12(7):493-498.
    • (2005) Eur J Neurol. , vol.12 , Issue.7 , pp. 493-498
    • Aslanyan, S.1    Weir, C.J.2    McInnes, G.T.3    Reid, J.L.4    Walters, M.R.5    Lees, K.R.6
  • 159
    • 84989229121 scopus 로고    scopus 로고
    • Effect of pre-stroke statin use on stroke severity and early functional recovery: a retrospective cohort study
    • Choi JC, Lee JS, Park TH, et al. Effect of pre-stroke statin use on stroke severity and early functional recovery: a retrospective cohort study. BMC Neurol. 2015; 15:120.
    • (2015) BMC Neurol. , vol.15 , pp. 120
    • Choi, J.C.1    Lee, J.S.2    Park, T.H.3
  • 160
    • 0032555154 scopus 로고    scopus 로고
    • Stroke protection by 3-hydroxy-3- methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase
    • Endres M, Laufs U, Huang Z, et al. Stroke protection by 3-hydroxy-3- methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proc Natl Acad Sci U S A. 1998;95(15):8880-8885.
    • (1998) Proc Natl Acad Sci U S A. , vol.95 , Issue.15 , pp. 8880-8885
    • Endres, M.1    Laufs, U.2    Huang, Z.3
  • 161
    • 0035073930 scopus 로고    scopus 로고
    • Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice
    • Amin-Hanjani S, Stagliano NE, Yamada M, Huang PL, Liao JK, Moskowitz MA. Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice. Stroke. 2001;32(4):980-986.
    • (2001) Stroke. , vol.32 , Issue.4 , pp. 980-986
    • Amin-Hanjani, S.1    Stagliano, N.E.2    Yamada, M.3    Huang, P.L.4    Liao, J.K.5    Moskowitz, M.A.6
  • 162
    • 21044435497 scopus 로고    scopus 로고
    • Protective effects of statins involving both eNOS and tPA in focal cerebral ischemia
    • Asahi M, Huang Z, Thomas S, et al. Protective effects of statins involving both eNOS and tPA in focal cerebral ischemia. J Cereb Blood Flow Metab. 2005;25(6): 722-729.
    • (2005) J Cereb Blood Flow Metab. , vol.25 , Issue.6 , pp. 722-729
    • Asahi, M.1    Huang, Z.2    Thomas, S.3
  • 163
    • 0038443056 scopus 로고    scopus 로고
    • Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke
    • Chen J, Zhang ZG, Li Y, et al. Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke. Ann Neurol 2003;53:743-751. Ann Neurol. 2005; 58(5):818-818.
    • (2003) Ann Neurol, Ann Neurol , vol.53 , Issue.5 , pp. 818-818
    • Chen, J.1    Zhang, Z.G.2    Li, Y.3
  • 164
    • 67649118113 scopus 로고    scopus 로고
    • Statins and ischemic stroke severity: cytoprotection
    • Goldstein LB. Statins and ischemic stroke severity: cytoprotection. Curr Atheroscler Rep. 2009;11(4):296-300.
    • (2009) Curr Atheroscler Rep. , vol.11 , Issue.4 , pp. 296-300
    • Goldstein, L.B.1
  • 165
    • 79956070020 scopus 로고    scopus 로고
    • Prospects of statins in Parkinson disease
    • Roy A, Pahan K. Prospects of statins in Parkinson disease. Neuroscientist. 2011; 17(3):244-255.
    • (2011) Neuroscientist. , vol.17 , Issue.3 , pp. 244-255
    • Roy, A.1    Pahan, K.2
  • 166
    • 84928434453 scopus 로고    scopus 로고
    • Cholesterol, statins, and dementia: what the cardiologist should know
    • Wanamaker BL, Swiger KJ, Blumenthal RS, Martin SS. Cholesterol, statins, and dementia: what the cardiologist should know. Clin Cardiol. 2015;38(4):243-250.
    • (2015) Clin Cardiol. , vol.38 , Issue.4 , pp. 243-250
    • Wanamaker, B.L.1    Swiger, K.J.2    Blumenthal, R.S.3    Martin, S.S.4
  • 167
    • 84866702836 scopus 로고    scopus 로고
    • alpha-Synuclein in Parkinson's disease
    • Stefanis L. alpha-Synuclein in Parkinson's disease. Cold Spring Harb Perspect Med. 2012;2(2):a009399.
    • (2012) Cold Spring Harb Perspect Med. , vol.2 , Issue.2
    • Stefanis, L.1
  • 168
    • 84947042506 scopus 로고    scopus 로고
    • Cholesterol-a putative endogenous contributor towards Parkinson's disease
    • Paul R, Choudhury A, Borah A. Cholesterol-a putative endogenous contributor towards Parkinson's disease. Neurochem Int. 2015;90:125-133.
    • (2015) Neurochem Int. , vol.90 , pp. 125-133
    • Paul, R.1    Choudhury, A.2    Borah, A.3
  • 169
    • 84962159996 scopus 로고    scopus 로고
    • Statin use and the risk of Parkinson's disease: an updated meta-analysis
    • Bai S, Song Y, Huang X, et al. Statin use and the risk of Parkinson's disease: an updated meta-analysis. PLoS One. 2016;11(3):e0152564.
    • (2016) PLoS One. , vol.11 , Issue.3
    • Bai, S.1    Song, Y.2    Huang, X.3
  • 170
    • 85016581638 scopus 로고    scopus 로고
    • Confounding of the association between statins and Parkinson disease: systematic review and meta-analysis
    • [Epub ahead of print].
    • Bykov K, Yoshida K, Weisskopf MG, Gagne JJ. Confounding of the association between statins and Parkinson disease: systematic review and meta-analysis. Pharmacoepidemiol Drug Saf. 2016. [Epub ahead of print].
    • (2016) Pharmacoepidemiol Drug Saf
    • Bykov, K.1    Yoshida, K.2    Weisskopf, M.G.3    Gagne, J.J.4
  • 171
    • 77954556989 scopus 로고    scopus 로고
    • Can statins prevent or help treat Alzheimer's disease?
    • McGuinness B, Passmore P. Can statins prevent or help treat Alzheimer's disease? J Alzheimers Dis. 2010;20(3):925-933.
    • (2010) J Alzheimers Dis. , vol.20 , Issue.3 , pp. 925-933
    • McGuinness, B.1    Passmore, P.2
  • 173
    • 84894226758 scopus 로고    scopus 로고
    • Statin therapy reduces the Mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation
    • Parihar SP, Guler R, Khutlang R, et al. Statin therapy reduces the Mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation. J Infect Dis. 2014;209(5):754-763.
    • (2014) J Infect Dis. , vol.209 , Issue.5 , pp. 754-763
    • Parihar, S.P.1    Guler, R.2    Khutlang, R.3
  • 174
    • 42449120103 scopus 로고    scopus 로고
    • Statin (cerivastatin) protects mice against sepsis-related death via reduced proinflammatory cytokines and enhanced bacterial clearance
    • Chaudhry MZ, Wang JH, Blankson S, Redmond HP. Statin (cerivastatin) protects mice against sepsis-related death via reduced proinflammatory cytokines and enhanced bacterial clearance. Surg Infect (Larchmt). 2008;9(2):183-194.
    • (2008) Surg Infect (Larchmt). , vol.9 , Issue.2 , pp. 183-194
    • Chaudhry, M.Z.1    Wang, J.H.2    Blankson, S.3    Redmond, H.P.4
  • 175
    • 84884557138 scopus 로고    scopus 로고
    • Simvastatin enhances protection against Listeria monocytogenes infection in mice by counteracting Listeria-induced phagosomal escape
    • Parihar SP, Guler R, Lang DM, Suzuki H, Marais AD, Brombacher F. Simvastatin enhances protection against Listeria monocytogenes infection in mice by counteracting Listeria-induced phagosomal escape. PLoS One. 2013;8(9):e75490.
    • (2013) PLoS One. , vol.8 , Issue.9
    • Parihar, S.P.1    Guler, R.2    Lang, D.M.3    Suzuki, H.4    Marais, A.D.5    Brombacher, F.6
  • 176
    • 84874629217 scopus 로고    scopus 로고
    • Statins inhibit in vitro virulence phenotypes of Pseudomonas aeruginosa
    • Hennessy E, Mooij MJ, Legendre C, et al. Statins inhibit in vitro virulence phenotypes of Pseudomonas aeruginosa. J Antibiot (Tokyo). 2013;66(2):99-101.
    • (2013) J Antibiot (Tokyo). , vol.66 , Issue.2 , pp. 99-101
    • Hennessy, E.1    Mooij, M.J.2    Legendre, C.3
  • 177
    • 31844451010 scopus 로고    scopus 로고
    • Anti-inflammatory effects of statins: clinical evidence and basic mechanisms
    • Jain MK, Ridker PM. Anti-inflammatory effects of statins: clinical evidence and basic mechanisms. Nat Rev Drug Discov. 2005;4(12):977-987.
    • (2005) Nat Rev Drug Discov. , vol.4 , Issue.12 , pp. 977-987
    • Jain, M.K.1    Ridker, P.M.2
  • 178
    • 84908246815 scopus 로고    scopus 로고
    • Current perspectives in HIV post-exposure prophylaxis
    • Sultan B, Benn P, Waters L. Current perspectives in HIV post-exposure prophylaxis. HIV AIDS (Auckl). 2014;6:147-158.
    • (2014) HIV AIDS (Auckl). , vol.6 , pp. 147-158
    • Sultan, B.1    Benn, P.2    Waters, L.3
  • 179
    • 0033873920 scopus 로고    scopus 로고
    • Hyperlipidemia associated with HIV protease inhibitor use: pathophysiology, prevalence, risk factors and treatment
    • Penzak SR, Chuck SK. Hyperlipidemia associated with HIV protease inhibitor use: pathophysiology, prevalence, risk factors and treatment. Scand J Infect Dis. 2000;32(2):111-123.
    • (2000) Scand J Infect Dis. , vol.32 , Issue.2 , pp. 111-123
    • Penzak, S.R.1    Chuck, S.K.2
  • 180
    • 84930181169 scopus 로고    scopus 로고
    • A systematic review of the usefulness of statin therapy in HIV-infected patients
    • Feinstein MJ, Achenbach CJ, Stone NJ, Lloyd-Jones DM. A systematic review of the usefulness of statin therapy in HIV-infected patients. Am J Cardiol. 2015; 115(12):1760-1766.
    • (2015) Am J Cardiol. , vol.115 , Issue.12 , pp. 1760-1766
    • Feinstein, M.J.1    Achenbach, C.J.2    Stone, N.J.3    Lloyd-Jones, D.M.4
  • 181
    • 0033813398 scopus 로고    scopus 로고
    • Safety and efficacy of HMG-CoA reductase inhibitors for treatment of hyperlipidemia in patients with HIV infection
    • Penzak SR, Chuck SK, Stajich GV. Safety and efficacy of HMG-CoA reductase inhibitors for treatment of hyperlipidemia in patients with HIV infection. Pharmacotherapy. 2000;20(9):1066-1071.
    • (2000) Pharmacotherapy. , vol.20 , Issue.9 , pp. 1066-1071
    • Penzak, S.R.1    Chuck, S.K.2    Stajich, G.V.3
  • 182
    • 4344566427 scopus 로고    scopus 로고
    • Statins inhibit HIV-1 infection by down-regulating Rho activity
    • del Real G, Jimenez-Baranda S, Mira E, et al. Statins inhibit HIV-1 infection by down-regulating Rho activity. J Exp Med. 2004;200(4):541-547.
    • (2004) J Exp Med. , vol.200 , Issue.4 , pp. 541-547
    • del Real, G.1    Jimenez-Baranda, S.2    Mira, E.3
  • 183
    • 32944456977 scopus 로고    scopus 로고
    • Statins could be used to control replication of some viruses, including HIV-1
    • Gilbert C, Bergeron M, Methot S, Giguere JF, Tremblay MJ. Statins could be used to control replication of some viruses, including HIV-1. Viral Immunol. 2005;18(3):474-489.
    • (2005) Viral Immunol. , vol.18 , Issue.3 , pp. 474-489
    • Gilbert, C.1    Bergeron, M.2    Methot, S.3    Giguere, J.F.4    Tremblay, M.J.5
  • 184
    • 85013403319 scopus 로고    scopus 로고
    • NIH Medline Plus Magazine
    • Understanding Cholesterol and Heart Health. NIH Medline Plus Magazine.Available at: www.medlineplus.gov185.
  • 185
    • 84925518081 scopus 로고    scopus 로고
    • Rosuvastatin pharmacokinetics and pharmacogenetics in Caucasian and Asian subjects residing in the United States.
    • Birmingham BK, Bujac SR, Elsby R, et al. Rosuvastatin pharmacokinetics and pharmacogenetics in Caucasian and Asian subjects residing in the United States. Eur J Clin Pharmacol. 2015;71(3):329-340.
    • (2015) Eur J Clin Pharmacol. , vol.71 , Issue.3 , pp. 329-340
    • Birmingham, B.K.1    Bujac, S.R.2    Elsby, R.3
  • 186
    • 84867036526 scopus 로고    scopus 로고
    • Pediatric pharmacogenomics: a systematic assessment of ontogeny and genetic variation to guide the design of statin studies in children
    • Wagner J, Leeder JS. Pediatric pharmacogenomics: a systematic assessment of ontogeny and genetic variation to guide the design of statin studies in children. Pediatr Clin North Am. 2012;59(5):1017-1037.
    • (2012) Pediatr Clin North Am. , vol.59 , Issue.5 , pp. 1017-1037
    • Wagner, J.1    Leeder, J.S.2
  • 188
    • 84949321606 scopus 로고    scopus 로고
    • The agenda for familial hypercholesterolemia: a scientific statement from the American Heart Association
    • Gidding SS, Champagne MA, de Ferranti SD, et al. The agenda for familial hypercholesterolemia: a scientific statement from the American Heart Association. Circulation. 2015;132(22):2167-2192.
    • (2015) Circulation. , vol.132 , Issue.22 , pp. 2167-2192
    • Gidding, S.S.1    Champagne, M.A.2    de Ferranti, S.D.3
  • 189
    • 84903717113 scopus 로고    scopus 로고
    • Lipid, blood pressure and kidney update 2013
    • Banach M, Serban C, Aronow WS, et al. Lipid, blood pressure and kidney update 2013. Int Urol Nephrol. 2014;46(5):947-961.
    • (2014) Int Urol Nephrol. , vol.46 , Issue.5 , pp. 947-961
    • Banach, M.1    Serban, C.2    Aronow, W.S.3
  • 190
    • 0003878910 scopus 로고    scopus 로고
    • Are You Taking the Right Treatment for Your High Cholesterol? Consumer Reports. Available at: www.ConsumerReports.org191.
    • Consumer Reports
  • 191
    • 85013443566 scopus 로고    scopus 로고
    • Institute for Clinical and Economic Review. PCSK9 Inhibitors for Treatment of High Cholesterol: Effectiveness, Value, and Value-Based Price Benchmarks Draft Report. 2015. Available at: https://icer-review.org/wp-content/uploads/2016/01/ Final-Report-for-Posting-11-24-15-1.pdf
    • (2015)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.