-
1
-
-
0029119711
-
Effect of pravastatin on outcomes after cardiac transplantation
-
Kobashigawa JA, Katznelson S, Laks H et al (1995) Effect of pravastatin on outcomes after cardiac transplantation. N Engl J Med 333:621-627
-
(1995)
N Engl J Med
, vol.333
, pp. 621-627
-
-
Kobashigawa, J.A.1
Katznelson, S.2
Laks, H.3
-
2
-
-
33947509525
-
The immunopa-thology of multiple sclerosis. An overview
-
Lassmann H, Brück W, Lucchinetti CF (2007) The immunopa-thology of multiple sclerosis. An overview. Brain Pathol 17:210-218
-
(2007)
Brain Pathol
, vol.17
, pp. 210-218
-
-
Lassmann, H.1
Brück, W.2
Lucchinetti, C.F.3
-
3
-
-
0033538533
-
Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin
-
DOI 10.1016/S0304-3940(99)00414-0, PII S0304394099004140
-
Stanislaus R, Pahan K, Singh AK, Singh I (1999) Amelioration of experimental allergic encephalomyelitis in Lewis rats by lova-statin. Neurosci Lett 269:71-74 (Pubitemid 29335415)
-
(1999)
Neuroscience Letters
, vol.269
, Issue.2
, pp. 71-74
-
-
Stanislaus, R.1
Pahan, K.2
Singh, A.K.3
Singh, I.4
-
4
-
-
0035888090
-
Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis
-
DOI 10.1002/jnr.1207
-
Stanislaus R, Singh AK, Singh I (2001) Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis. J Neurosci Res 66:155-162 (Pubitemid 32912284)
-
(2001)
Journal of Neuroscience Research
, vol.66
, Issue.2
, pp. 155-162
-
-
Stanislaus, R.1
Singh, A.K.2
Singh, I.3
-
5
-
-
0037038402
-
The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease
-
DOI 10.1038/nature01158
-
Youssef S, Stuve O, Patarroyo JC et al (2002) The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature 420:78-84 (Pubitemid 35291443)
-
(2002)
Nature
, vol.420
, Issue.6911
, pp. 78-84
-
-
Youssef, S.1
Stuve, O.2
Patarroyo, J.O.3
Ruiz, P.J.4
Radosevich, J.L.5
Mi Hur, E.6
Bravo, M.7
Mitchell, D.J.8
Sobel, R.A.9
Stelnman, L.10
Zamvil, S.S.11
-
6
-
-
40849089388
-
Therapeutic potential of statins in multiple sclerosis: Immune modulation, neuroprotection and neurorepair
-
DOI 10.2217/14796708.3.2.153
-
Markovic-Plese S, Singh AK, Singh I (2008) Therapeutic potential of statins in multiple sclerosis: immune modulation, neuroprotection and neurorepair. Future Neurol 3:153-167 (Pubitemid 351395069)
-
(2008)
Future Neurology
, vol.3
, Issue.2
, pp. 153-167
-
-
Markovic-Plese, S.1
Singh, A.K.2
Singh, I.3
-
7
-
-
58149377174
-
Negative impact of statins on oligodendrocytes and myelin formation in vitro and in vivo
-
Klopfleisch S, Merkler D, Schmitz M et al (2008) Negative impact of statins on oligodendrocytes and myelin formation in vitro and in vivo. J Neurosci 28:13609-13614
-
(2008)
J Neurosci
, vol.28
, pp. 13609-13614
-
-
Klopfleisch, S.1
Merkler, D.2
Schmitz, M.3
-
8
-
-
65649133589
-
Statin therapy inhibits remyelination in the central nervous system
-
Miron VE, Zehntner SP, Kuhlmann T et al (2009) Statin therapy inhibits remyelination in the central nervous system. Am J Pathol 174:1880-1890
-
(2009)
Am J Pathol
, vol.174
, pp. 1880-1890
-
-
Miron, V.E.1
Zehntner, S.P.2
Kuhlmann, T.3
-
9
-
-
2442561768
-
Oral simvastatin treatment in relapsing-remitting multiple sclerosis
-
DOI 10.1016/S0140-6736(04)16205-3, PII S0140673604162053
-
Vollmer T, Key L, Durkalski V et al (2004) Oral simvastatin treatment in relapsing-remitting multiple sclerosis. Lancet 363:1607-1608 (Pubitemid 38625664)
-
(2004)
Lancet
, vol.363
, Issue.9421
, pp. 1607-1608
-
-
Vollmer, T.1
Key, L.2
Durkalski, V.3
Tyor, W.4
Corboy, J.5
Markovic-Plese, S.6
Preiningerova, J.7
Rizzo, M.8
Singh, I.9
-
10
-
-
44849127754
-
Oral high-dose ator-vastatin treatment in relapsing-remitting multiple sclerosis
-
Paul F, Waiczies S, Wuerfel J et al (2008) Oral high-dose ator-vastatin treatment in relapsing-remitting multiple sclerosis. PLoS ONE 3:e1928
-
(2008)
PLoS ONE
, vol.3
-
-
Paul, F.1
Waiczies, S.2
Wuerfel, J.3
-
11
-
-
77955023091
-
Simvastatin treatment in patients with relapsing-remitting multiple sclerosis receiving interferon beta 1a: A double-blind randomized controlled trial
-
Togha M, Karvigh SA, Nabavi M et al (2010) Simvastatin treatment in patients with relapsing-remitting multiple sclerosis receiving interferon beta 1a: a double-blind randomized controlled trial. Mult Scler 16:848-854
-
(2010)
Mult Scler
, vol.16
, pp. 848-854
-
-
Togha, M.1
Karvigh, S.A.2
Nabavi, M.3
-
12
-
-
56549086423
-
Combining beta interferon and atorvastatin may increase disease activity in multiple sclerosis
-
Birnbaum G, Cree B, Altafullah I, Zinser M, Reder AT (2008) Combining beta interferon and atorvastatin may increase disease activity in multiple sclerosis. Neurology 71:1390-1395
-
(2008)
Neurology
, vol.71
, pp. 1390-1395
-
-
Birnbaum, G.1
Cree, B.2
Altafullah, I.3
Zinser, M.4
Reder, A.T.5
-
13
-
-
67649488058
-
Effect of statins on clinical and molecular responses to intramuscular interferon beta-1a
-
Rudick RA, Pace A, Rani MR et al (2009) Effect of statins on clinical and molecular responses to intramuscular interferon beta-1a. Neurology 72:1989-1993
-
(2009)
Neurology
, vol.72
, pp. 1989-1993
-
-
Rudick, R.A.1
Pace, A.2
Rani, M.R.3
-
14
-
-
77954688218
-
Atorvastatin combined to interferon to verify the efficacy (ACTIVE) in relapsing-remitting active multiple sclerosis patients: A longitudinal controlled trial of combination therapy
-
Lanzillo R, Orefice G, Quarantelli M et al (2010) Atorvastatin combined to interferon to verify the efficacy (ACTIVE) in relapsing-remitting active multiple sclerosis patients: a longitudinal controlled trial of combination therapy. Mult Scler 16:450-454
-
(2010)
Mult Scler
, vol.16
, pp. 450-454
-
-
Lanzillo, R.1
Orefice, G.2
Quarantelli, M.3
-
15
-
-
79960341237
-
Simvastatin as add-on therapy to interferon beta-1a for relapsing-remitting multiple sclerosis (SIMCOMBIN study): A placebo-controlled randomised phase 4 trial
-
Sorensen PS, Lycke J, Erälinna JP et al (2011) Simvastatin as add-on therapy to interferon beta-1a for relapsing-remitting multiple sclerosis (SIMCOMBIN study): a placebo-controlled randomised phase 4 trial. Lancet Neurol 10:691-701
-
(2011)
Lancet Neurol
, vol.10
, pp. 691-701
-
-
Sorensen, P.S.1
Lycke, J.2
Erälinna, J.P.3
-
16
-
-
0027418515
-
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial
-
IFNB Multiple Sclerosis Study Group
-
IFNB Multiple Sclerosis Study Group (1993) Interferon beta-lb is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 43:655-661
-
(1993)
Neurology
, vol.43
, pp. 655-661
-
-
-
17
-
-
74049148874
-
SWiss atorvastatin and interferon beta-1b trial in multiple sclerosis (SWABIMS)-rationale, design and methodology
-
SWABIMS Study Group
-
Kamm CP, Mattle HP, SWABIMS Study Group (2009) SWiss atorvastatin and interferon beta-1b trial in multiple sclerosis (SWABIMS)-rationale, design and methodology. Trials 14:110-115
-
(2009)
Trials
, vol.14
, pp. 110-115
-
-
Kamm, C.P.1
Mattle, H.P.2
-
19
-
-
0021035886
-
Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
-
Kurtzke JF (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33:1444-1452 (Pubitemid 14237132)
-
(1983)
Neurology
, vol.33
, Issue.11
, pp. 1444-1452
-
-
Kurtzke, J.F.1
-
20
-
-
0032837796
-
The multiple sclerosis functional composite measure (MSFC): An integrated approach to MS clinical outcome assessment
-
Fischer JS, Rudick RA, Cutter GR, Reingold SC (1999) The multiple sclerosis functional composite measure (MSFC). An integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler 5:244-250 (Pubitemid 29405620)
-
(1999)
Multiple Sclerosis
, vol.5
, Issue.4
, pp. 244-250
-
-
Fischer, J.S.1
Rudick, R.A.2
Cutter, G.R.3
Reingold, S.C.4
-
21
-
-
0034533147
-
Statins as a newly recognized type of immunomodulator
-
DOI 10.1038/82219
-
Kwak B, Mulhaupt F, Myit S, Mach F (2000) Statins as a newly recognized type of immunomodulator. Nat Med 6:1399-1402 (Pubitemid 32001026)
-
(2000)
Nature Medicine
, vol.6
, Issue.12
, pp. 1399-1402
-
-
Kwak, B.1
Mulhaupt, F.2
Myit, S.3
Mach, F.4
-
22
-
-
36749013849
-
Atorvastatin: A safety and tolerability profile
-
Arca M (2007) Atorvastatin: a safety and tolerability profile. Drugs 67(1):63-69
-
(2007)
Drugs
, vol.67
, Issue.1
, pp. 63-69
-
-
Arca, M.1
-
23
-
-
0034771462
-
Safety of HMG-CoA reductase inhibitors: Focus on atorvastatin
-
DOI 10.1023/A:1011908004965
-
Bernini F, Poli A, Paoletti R (2001) Safety of HMG-CoA reductase inhibitors: focus on atorvastatin. Cardiovasc Drugs Ther 15:211-218 (Pubitemid 33010603)
-
(2001)
Cardiovascular Drugs and Therapy
, vol.15
, Issue.3
, pp. 211-218
-
-
Bernini, F.1
Poli, A.2
Paoletti, R.3
-
24
-
-
15944410609
-
Intensive lipid lowering with atorvastatin in patients with stable coronary disease
-
DOI 10.1056/NEJMoa050461
-
LaRosa JC, Grundy SM, Waters DD et al (2005) Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med 352:1425-1435 (Pubitemid 40471450)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.14
, pp. 1425-1435
-
-
LaRosa, J.C.1
Grundy, S.M.2
Waters, D.D.3
Shear, C.4
Barter, P.5
Fruchart, J.-C.6
Gotto, A.M.7
Greten, H.8
Kastelein, J.J.P.9
Shepherd, J.10
Wenger, N.K.11
-
25
-
-
84883491080
-
-
Geneva: International Conference on Harmo-nisation of Technical Requirements for Registration of Pharmaceuticals for Human Use, June 10 Accessed January 8, 2010
-
ICH harmonised tripartite guideline-guideline for good clinical practice: E6(R1). Geneva: International Conference on Harmo-nisation of Technical Requirements for Registration of Pharmaceuticals for Human Use, June 10, 1996. Accessed January 8, 2010, at http://www.ich.org/LOB/media/MEDIA482.pdf
-
(1996)
ICH Harmonised Tripartite Guideline-guideline for Good Clinical Practice: E6(R1)
-
-
-
27
-
-
20444501009
-
Unified segmentation
-
DOI 10.1016/j.neuroimage.2005.02.018, PII S1053811905001102
-
Ashburner J, Friston KJ (2005) Unified segmentation. Neuroim-age 26:839-851 (Pubitemid 40825026)
-
(2005)
NeuroImage
, vol.26
, Issue.3
, pp. 839-851
-
-
Ashburner, J.1
Friston, K.J.2
-
28
-
-
55049090803
-
Cross-validation of brain segmentation by SPM5 and SIENAX
-
Lee H, Prohovnik I (2008) Cross-validation of brain segmentation by SPM5 and SIENAX. Psychiatry Res 164:172-177
-
(2008)
Psychiatry Res
, vol.164
, pp. 172-177
-
-
Lee, H.1
Prohovnik, I.2
-
29
-
-
59649119762
-
A novel method for analyzing DSCE-images with an application to tumor grading
-
Slotboom J, Schaer R, Ozdoba C et al (2008) A novel method for analyzing DSCE-images with an application to tumor grading. Invest Radiol 43:843-853
-
(2008)
Invest Radiol
, vol.43
, pp. 843-853
-
-
Slotboom, J.1
Schaer, R.2
Ozdoba, C.3
-
30
-
-
0003997295
-
Thirty-fifth report
-
WHO Expert Committee on Biological Standardization
-
WHO Expert Committee on Biological Standardization (1985) Thirty-fifth report. World Health Organ Tech Rep Ser 725:1-140
-
(1985)
World Health Organ Tech Rep Ser
, vol.725
, pp. 1-140
-
-
-
31
-
-
0036329631
-
Differential effects of three interferon betas on neutralising antibodies in patients with multiple sclerosis: A follow up study in an independent laboratory
-
Bertolotto A, Malucchi S, Sala A et al (2002) Differential effects of three interferon betas on neutralising antibodies in patients with multiple sclerosis: a follow up study in an independent laboratory. J Neurol Neurosurg Psychiatry 73:148-153
-
(2002)
J Neurol Neurosurg Psychiatry
, vol.73
, pp. 148-153
-
-
Bertolotto, A.1
Malucchi, S.2
Sala, A.3
-
32
-
-
0027521002
-
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo- controlled trial
-
Paty DW, Li DK, The UBC MS/MRI Study Group and the IFNB Multiple Sclerosis Study Group (1993) Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 43:662-667 (Pubitemid 23121952)
-
(1993)
Neurology
, vol.43
, Issue.4
, pp. 662-667
-
-
Paty, D.W.1
Li, D.K.B.2
-
33
-
-
0037044284
-
Statins as immunomodulators: Comparison with interferon-beta 1b in MS
-
Neuhaus O, Strasser-Fuchs S, Fazekas F et al (2002) Statins as immunomodulators: comparison with interferon-beta 1b in MS. Neurology 59:990-997
-
(2002)
Neurology
, vol.59
, pp. 990-997
-
-
Neuhaus, O.1
Strasser-Fuchs, S.2
Fazekas, F.3
-
34
-
-
39749119452
-
Statins block interferon signaling in human immune cells: Potential loss of the therapeutic effect of IFN-B in multiple sclerosis
-
Dhawan N, Reder AT (2007) Statins block interferon signaling in human immune cells: potential loss of the therapeutic effect of IFN-B in multiple sclerosis. Neurology 68(suppl 1):A364
-
(2007)
Neurology
, vol.68
, Issue.SUPPL. 1
-
-
Dhawan, N.1
Reder, A.T.2
-
35
-
-
2942622588
-
Different effects of simvastatin and interferon beta on the proteolytic activity of matrix metalloproteinases
-
DOI 10.1001/archneur.61.6.929
-
Kieseier BC, Archelos JJ, Hartung HP (2004) Different effects of simvastatin and interferon beta on the proteolytic activity of matrix metalloproteinases. Arch Neurol 61:929-932 (Pubitemid 38747335)
-
(2004)
Archives of Neurology
, vol.61
, Issue.6
, pp. 929-932
-
-
Kieseier, B.C.1
Archelos, J.J.2
Hartung, H.-P.3
-
36
-
-
77950209814
-
Vascular comor-bidity is associated with more rapid disability progression in multiple sclerosis
-
Marrie RA, Rudick R, Horwitz R et al (2010) Vascular comor-bidity is associated with more rapid disability progression in multiple sclerosis. Neurology 74:1041-1047
-
(2010)
Neurology
, vol.74
, pp. 1041-1047
-
-
Marrie, R.A.1
Rudick, R.2
Horwitz, R.3
-
37
-
-
60549108178
-
Comorbidity delays diagnosis and increases disability at diagnosis in MS
-
Marrie RA, Horwitz R, Cutter G et al (2009) Comorbidity delays diagnosis and increases disability at diagnosis in MS. Neurology 72:117-124
-
(2009)
Neurology
, vol.72
, pp. 117-124
-
-
Marrie, R.A.1
Horwitz, R.2
Cutter, G.3
|