메뉴 건너뛰기




Volumn 4, Issue JUN, 2016, Pages

Biomaterials for the treatment of alzheimer's disease

Author keywords

Alzheimer's disease; Biomaterials; Delivery systems; Liposomes; Nanoparticles; Scaffolds

Indexed keywords

BIOMATERIALS; DISEASE CONTROL; LIPOSOMES; NANOPARTICLES; NEURODEGENERATIVE DISEASES; SCAFFOLDS; SCAFFOLDS (BIOLOGY);

EID: 85012205249     PISSN: None     EISSN: 22964185     Source Type: Journal    
DOI: 10.3389/fbioe.2016.00049     Document Type: Review
Times cited : (54)

References (71)
  • 1
    • 46149107512 scopus 로고    scopus 로고
    • Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta
    • Adlard, P. A., Cherny, R. A., Finkelstein, D. I., Gautier, E., Robb, E., Cortes, M., et al. (2008). Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta. Neuron 59, 43-55. doi:10.1016/j.neuron.2008.06.018
    • (2008) Neuron , vol.59 , pp. 43-55
    • Adlard, P.A.1    Cherny, R.A.2    Finkelstein, D.I.3    Gautier, E.4    Robb, E.5    Cortes, M.6
  • 2
    • 84858225391 scopus 로고    scopus 로고
    • Alzheimer's disease facts and figures
    • Alzheimer's Association. (2012). Alzheimer's disease facts and figures. Alzheimers Dement. 8, 131-168. doi:10.1016/j.jalz.2012.02.001
    • (2012) Alzheimers Dement , vol.8 , pp. 131-168
  • 3
    • 84886600387 scopus 로고    scopus 로고
    • Therapeutics of Alzheimer's disease: past, present and future
    • Anand, R., Gill, K. D., and Mahdi, A. A. (2014). Therapeutics of Alzheimer's disease: past, present and future. Neuropharmacology 76(Pt A), 27-50. doi:10.1016/j.neuropharm.2013.07.004
    • (2014) Neuropharmacology , vol.76 , pp. 27-50
    • Anand, R.1    Gill, K.D.2    Mahdi, A.A.3
  • 4
    • 61749103704 scopus 로고    scopus 로고
    • Protective effect of quercetin in primary neurons against Abeta(1-42): relevance to Alzheimer's disease
    • Ansari, M. A., Abdul, H. M., Joshi, G., Opii, W. O., and Butterfield, D. A. (2009). Protective effect of quercetin in primary neurons against Abeta(1-42): relevance to Alzheimer's disease. J. Nutr. Biochem. 20, 269-275. doi:10.1016/j.jnutbio.2008.03.002
    • (2009) J. Nutr. Biochem , vol.20 , pp. 269-275
    • Ansari, M.A.1    Abdul, H.M.2    Joshi, G.3    Opii, W.O.4    Butterfield, D.A.5
  • 5
    • 84907512825 scopus 로고    scopus 로고
    • A critical analysis of the 'amyloid cascade hypothesis'
    • Armstrong, R. A. (2014). A critical analysis of the 'amyloid cascade hypothesis'. Folia Neuropathol. 3, 211-225. doi:10.5114/fn.2014.45562
    • (2014) Folia Neuropathol , vol.3 , pp. 211-225
    • Armstrong, R.A.1
  • 6
    • 84885456781 scopus 로고    scopus 로고
    • Review article what causes Alzheimer's disease?
    • Armstrong, R. A. (2013). Review article what causes Alzheimer's disease? Folia Neuropathol. 51, 169-188. doi:10.5114/fn.2013.37702
    • (2013) Folia Neuropathol , vol.51 , pp. 169-188
    • Armstrong, R.A.1
  • 7
    • 53549135761 scopus 로고    scopus 로고
    • A study of rivastigmine liposomes for delivery into the brain through intranasal route
    • Arumugam, K., Subramanian, G. S., Mallayasamy, S. R., Averineni, R. K., Reddy, M. S., and Udupa, N. (2008). A study of rivastigmine liposomes for delivery into the brain through intranasal route. Acta Pharm. 58, 287-297. doi:10.2478/v10007-008-0014-3
    • (2008) Acta Pharm , vol.58 , pp. 287-297
    • Arumugam, K.1    Subramanian, G.S.2    Mallayasamy, S.R.3    Averineni, R.K.4    Reddy, M.S.5    Udupa, N.6
  • 8
    • 2342471420 scopus 로고    scopus 로고
    • The blood-brain barrier: an overview: structure, regulation, and clinical implications
    • Ballabh, P., Braun, A., and Nedergaard, M. (2004). The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol. Dis. 16, 1-13. doi:10.1016/j.nbd.2003.12.016
    • (2004) Neurobiol. Dis , vol.16 , pp. 1-13
    • Ballabh, P.1    Braun, A.2    Nedergaard, M.3
  • 9
    • 34548427504 scopus 로고    scopus 로고
    • Active targeting of brain tumors using nanocarriers
    • Beduneau, A., Saulnier, P., and Benoit, J. P. (2007). Active targeting of brain tumors using nanocarriers. Biomaterials 28, 4947-4967. doi:10.1016/j.biomaterials.2007.06.011
    • (2007) Biomaterials , vol.28 , pp. 4947-4967
    • Beduneau, A.1    Saulnier, P.2    Benoit, J.P.3
  • 12
    • 84861235844 scopus 로고    scopus 로고
    • Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells
    • Brunholz, S., Sisodia, S., Lorenzo, A., Deyts, C., Kins, S., and Morfini, G. (2012). Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells. Exp. Brain Res. 217, 353-364. doi:10.1007/s00221-011-2870-1
    • (2012) Exp. Brain Res , vol.217 , pp. 353-364
    • Brunholz, S.1    Sisodia, S.2    Lorenzo, A.3    Deyts, C.4    Kins, S.5    Morfini, G.6
  • 13
    • 79956323181 scopus 로고    scopus 로고
    • The binding affinity of anti-Abeta1-42 MAb-decorated nanoliposomes to Abeta1-42 peptides in vitro and to amyloid deposits in post-mortem tissue
    • Canovi, M., Markoutsa, E., Lazar, A. N., Pampalakis, G., Clemente, C., Re, F., et al. (2011). The binding affinity of anti-Abeta1-42 MAb-decorated nanoliposomes to Abeta1-42 peptides in vitro and to amyloid deposits in post-mortem tissue. Biomaterials 32, 5489-5497. doi:10.1016/j.biomaterials.2011.04.020
    • (2011) Biomaterials , vol.32 , pp. 5489-5497
    • Canovi, M.1    Markoutsa, E.2    Lazar, A.N.3    Pampalakis, G.4    Clemente, C.5    Re, F.6
  • 14
    • 0034964390 scopus 로고    scopus 로고
    • Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice
    • Cherny, R. A., Atwood, C. S., Xilinas, M. E., Gray, D. N., Jones, W. D., McLean, C. A., et al. (2001). Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron 30, 665-676. doi:10.1016/S0896-6273(01)00317-8
    • (2001) Neuron , vol.30 , pp. 665-676
    • Cherny, R.A.1    Atwood, C.S.2    Xilinas, M.E.3    Gray, D.N.4    Jones, W.D.5    McLean, C.A.6
  • 15
    • 77951776829 scopus 로고    scopus 로고
    • Alzheimer's disease: strategies for disease modification
    • Citron, M. (2010). Alzheimer's disease: strategies for disease modification. Nat. Rev. Drug Discov. 9, 387-398. doi:10.1038/nrd2896
    • (2010) Nat. Rev. Drug Discov , vol.9 , pp. 387-398
    • Citron, M.1
  • 16
    • 84884930643 scopus 로고    scopus 로고
    • Molecular structure of RADA16-I designer self-assembling peptide nanofibers
    • Cormier, A. R., Pang, X., Zimmerman, M. I., Zhou, H.-X., and Paravastu, A. K. (2013). Molecular structure of RADA16-I designer self-assembling peptide nanofibers. ACS Nano 7, 7562-7572. doi:10.1021/nn401562f
    • (2013) ACS Nano , vol.7 , pp. 7562-7572
    • Cormier, A.R.1    Pang, X.2    Zimmerman, M.I.3    Zhou, H.-X.4    Paravastu, A.K.5
  • 17
    • 84958102343 scopus 로고    scopus 로고
    • Designer self-assemble peptides maximize the therapeutic benefits of neural stem cell transplantation for Alzheimer's disease via enhancing neuron differentiation and paracrine action
    • Cui, G. H., Shao, S. J., Yang, J. J., Liu, J. R., and Guo, H. D. (2016). Designer self-assemble peptides maximize the therapeutic benefits of neural stem cell transplantation for Alzheimer's disease via enhancing neuron differentiation and paracrine action. Mol. Neurobiol. 53, 1108-1123. doi:10.1007/s12035-014-9069-y
    • (2016) Mol. Neurobiol , vol.53 , pp. 1108-1123
    • Cui, G.H.1    Shao, S.J.2    Yang, J.J.3    Liu, J.R.4    Guo, H.D.5
  • 18
    • 12344251715 scopus 로고    scopus 로고
    • Novel d-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases
    • Cui, Z., Lockman, P. R., Atwood, C. S., Hsu, C.-H., Gupte, A., Allen, D. D., et al. (2005). Novel d-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases. Eur. J. Pharm. Biopharm. 59, 263-272. doi:10.1016/j.ejpb.2004.07.009
    • (2005) Eur. J. Pharm. Biopharm , vol.59 , pp. 263-272
    • Cui, Z.1    Lockman, P.R.2    Atwood, C.S.3    Hsu, C.-H.4    Gupte, A.5    Allen, D.D.6
  • 19
    • 79955077392 scopus 로고    scopus 로고
    • Drug delivery strategies for Alzheimer's disease treatment
    • Di Stefano, A., Iannitelli, A., Laserra, S., and Sozio, P. (2011). Drug delivery strategies for Alzheimer's disease treatment. Expert Opin. Drug Deliv. 8, 581-603. doi:10.1517/17425247.2011.561311
    • (2011) Expert Opin. Drug Deliv , vol.8 , pp. 581-603
    • Di Stefano, A.1    Iannitelli, A.2    Laserra, S.3    Sozio, P.4
  • 20
    • 78649777075 scopus 로고    scopus 로고
    • Liposome-incorporated DHA increases neuronal survival by enhancing non-amyloidogenic APP processing
    • Eckert, G. P., Chang, S., Eckmann, J., Copanaki, E., Hagl, S., Hener, U., et al. (2011). Liposome-incorporated DHA increases neuronal survival by enhancing non-amyloidogenic APP processing. Biochim. Biophys. Acta 1808, 236-243. doi:10.1016/j.bbamem.2010.10.014
    • (2011) Biochim. Biophys. Acta , vol.1808 , pp. 236-243
    • Eckert, G.P.1    Chang, S.2    Eckmann, J.3    Copanaki, E.4    Hagl, S.5    Hener, U.6
  • 21
  • 22
    • 84920145312 scopus 로고    scopus 로고
    • Gold-nanoparticle-based multifunctional amyloid-β inhibitor against Alzheimer's disease
    • Gao, N., Sun, H., Dong, K., Ren, J., and Qu, X. (2015). Gold-nanoparticle-based multifunctional amyloid-β inhibitor against Alzheimer's disease. Chemistry 21, 829-835. doi:10.1002/chem.201404562
    • (2015) Chemistry , vol.21 , pp. 829-835
    • Gao, N.1    Sun, H.2    Dong, K.3    Ren, J.4    Qu, X.5
  • 23
    • 77953962852 scopus 로고    scopus 로고
    • Lipid-based nanoparticles with high binding affinity for amyloid-beta1-42 peptide
    • Gobbi, M., Re, F., Canovi, M., Beeg, M., Gregori, M., Sesana, S., et al. (2010). Lipid-based nanoparticles with high binding affinity for amyloid-beta1-42 peptide. Biomaterials 31, 6519-6529. doi:10.1016/j.biomaterials.2010.04.044
    • (2010) Biomaterials , vol.31 , pp. 6519-6529
    • Gobbi, M.1    Re, F.2    Canovi, M.3    Beeg, M.4    Gregori, M.5    Sesana, S.6
  • 24
    • 49149118299 scopus 로고    scopus 로고
    • Liposome research in drug delivery: the early days
    • Gregoriadis, G. (2008). Liposome research in drug delivery: the early days. J. Drug Target. 16, 520-524. doi:10.1080/10611860802228350
    • (2008) J. Drug Target , vol.16 , pp. 520-524
    • Gregoriadis, G.1
  • 25
    • 61849127257 scopus 로고    scopus 로고
    • Recombinant human NGF-loaded microspheres promote survival of basal forebrain cholinergic neurons and improve memory impairments of spatial learning in the rat model of Alzheimer's disease with fimbria-fornix lesion
    • Gu, H., Long, D., Song, C., and Li, X. (2009). Recombinant human NGF-loaded microspheres promote survival of basal forebrain cholinergic neurons and improve memory impairments of spatial learning in the rat model of Alzheimer's disease with fimbria-fornix lesion. Neurosci. Lett. 453, 204-209. doi:10.1016/j.neulet.2009.02.027
    • (2009) Neurosci. Lett , vol.453 , pp. 204-209
    • Gu, H.1    Long, D.2    Song, C.3    Li, X.4
  • 26
    • 0035829720 scopus 로고    scopus 로고
    • Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila
    • Gunawardena, S., and Goldstein, L. S. (2001). Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. Neuron 32, 389-401. doi:10.1016/S0896-6273(01)00496-2
    • (2001) Neuron , vol.32 , pp. 389-401
    • Gunawardena, S.1    Goldstein, L.S.2
  • 27
    • 84966715143 scopus 로고    scopus 로고
    • Research progress in animal models and stem cell therapy for Alzheimer's disease
    • Han, F., Wang, W., and Chen, C. (2015). Research progress in animal models and stem cell therapy for Alzheimer's disease. J. Neurorestoratol. 3, 11-12. doi:10.2147/jn.s74160
    • (2015) J. Neurorestoratol , vol.3 , pp. 11-12
    • Han, F.1    Wang, W.2    Chen, C.3
  • 28
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease-progress and problems on the road to therapeutics
    • Hardy, J., and Selkoe, D. J. (2002). The amyloid hypothesis of Alzheimer's disease-progress and problems on the road to therapeutics. Science 297, 353-356. doi:10.1126/science.1072994
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 29
    • 0034612266 scopus 로고    scopus 로고
    • Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds
    • Holmes, T. C., de Lacalle, S., Su, X., Liu, G., Rich, A., et al. (2000). Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds. Proc. Natl. Acad. Sci. U.S.A. 97, 6728-6733. doi:10.1073/pnas.97.12.6728
    • (2000) Proc. Natl. Acad. Sci. U.S.A , vol.97 , pp. 6728-6733
    • Holmes, T.C.1    de Lacalle, S.2    Su, X.3    Liu, G.4    Rich, A.5
  • 30
    • 84916631997 scopus 로고    scopus 로고
    • New drug treatments show neuroprotective effects in Alzheimer's and Parkinson's diseases
    • Hölscher, C. (2014). New drug treatments show neuroprotective effects in Alzheimer's and Parkinson's diseases. Neural. Regen. Res. 9, 1870-1873. doi:10.4103/1673-5374.145342
    • (2014) Neural. Regen. Res , vol.9 , pp. 1870-1873
    • Hölscher, C.1
  • 32
    • 84892885865 scopus 로고    scopus 로고
    • Allopregnanolone as regenerative therapeutic for Alzheimer's disease: translational development and clinical promise
    • Irwin, R. W., and Brinton, R. D. (2014). Allopregnanolone as regenerative therapeutic for Alzheimer's disease: translational development and clinical promise. Prog. Neurobiol. 113, 40-55. doi:10.1016/j.pneurobio.2013.08.004
    • (2014) Prog. Neurobiol , vol.113 , pp. 40-55
    • Irwin, R.W.1    Brinton, R.D.2
  • 33
    • 66549104205 scopus 로고    scopus 로고
    • Bridging physiology and pathology in AD
    • Kim, D., and Tsai, L. H. (2009). Bridging physiology and pathology in AD. Cell 137, 997-1000. doi:10.1016/j.cell.2009.05.042
    • (2009) Cell , vol.137 , pp. 997-1000
    • Kim, D.1    Tsai, L.H.2
  • 34
    • 84918591171 scopus 로고    scopus 로고
    • A review on Alzheimer's disease pathophysiology and its management: an update
    • Kumar, A., Singh, A., and Ekavali. (2015). A review on Alzheimer's disease pathophysiology and its management: an update. Pharmacol. Rep. 67, 195-203. doi:10.1016/j.pharep.2014.09.004
    • (2015) Pharmacol. Rep , vol.67 , pp. 195-203
    • Kumar, A.1    Singh, A.2    Ekavali3
  • 37
    • 84947648721 scopus 로고    scopus 로고
    • Nanoparticle-mediated growth factor delivery systems: a new way to treat Alzheimer's disease
    • Lauzon, M. A., Daviau, A., Marcos, B., and Faucheux, N. (2015). Nanoparticle-mediated growth factor delivery systems: a new way to treat Alzheimer's disease. J. Control Release 206, 187-205. doi:10.1016/j.jconrel.2015.03.024
    • (2015) J. Control Release , vol.206 , pp. 187-205
    • Lauzon, M.A.1    Daviau, A.2    Marcos, B.3    Faucheux, N.4
  • 38
    • 84866512594 scopus 로고    scopus 로고
    • Covalent bonding of GYIGSR to EVAL membrane surface to improve migration and adhesion of cultured neural stem/precursor cells
    • Li, Y., Liao, Y., Chang, H., and Young, T. (2013). Covalent bonding of GYIGSR to EVAL membrane surface to improve migration and adhesion of cultured neural stem/precursor cells. Colloids Surf. B Biointerfaces 102, 53-62. doi:10.1016/j.colsurfb.2012.08.054
    • (2013) Colloids Surf. B Biointerfaces , vol.102 , pp. 53-62
    • Li, Y.1    Liao, Y.2    Chang, H.3    Young, T.4
  • 39
    • 33748202940 scopus 로고    scopus 로고
    • Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance
    • Liu, G., Men, P., Harris, P. L., Rolston, R. K., Perry, G., and Smith, M. A. (2006). Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance. Neurosci. Lett. 406, 189-193. doi:10.1016/j.neulet.2006.07.020
    • (2006) Neurosci. Lett , vol.406 , pp. 189-193
    • Liu, G.1    Men, P.2    Harris, P.L.3    Rolston, R.K.4    Perry, G.5    Smith, M.A.6
  • 40
    • 64049104164 scopus 로고    scopus 로고
    • Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease
    • Liu, G., Men, P., Kudo, W., Perry, G., and Smith, M. A. (2009). Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease. Neurosci. Lett. 455, 187-190. doi:10.1016/j.neulet.2009.03.064
    • (2009) Neurosci. Lett , vol.455 , pp. 187-190
    • Liu, G.1    Men, P.2    Kudo, W.3    Perry, G.4    Smith, M.A.5
  • 41
    • 84869875871 scopus 로고    scopus 로고
    • Biodegradable PLGA-b-PEG polymeric nanoparticles: synthesis, properties, and nanomedical applications as drug delivery system
    • Locatelli, E., and Franchini, M. C. (2012). Biodegradable PLGA-b-PEG polymeric nanoparticles: synthesis, properties, and nanomedical applications as drug delivery system. J. Nanopart. Res. 14, 1316. doi:10.1007/s11051-012-1316-4
    • (2012) J. Nanopart. Res , vol.14 , pp. 1316
    • Locatelli, E.1    Franchini, M.C.2
  • 43
    • 33745377482 scopus 로고    scopus 로고
    • Quercetin reverses d-galactose induced neurotoxicity in mouse brain
    • Lu, J., Zheng, Y. L., Luo, L., Wu, D. M., Sun, D. X., and Feng, Y. J. (2006). Quercetin reverses d-galactose induced neurotoxicity in mouse brain. Behav. Brain Res. 171, 251-260. doi:10.1016/j.bbr.2006.03.043
    • (2006) Behav. Brain Res , vol.171 , pp. 251-260
    • Lu, J.1    Zheng, Y.L.2    Luo, L.3    Wu, D.M.4    Sun, D.X.5    Feng, Y.J.6
  • 44
    • 67650642274 scopus 로고    scopus 로고
    • Nanotechnological applications for the treatment of neurodegenerative disorders
    • Modi, G., Pillay, V., Choonara, Y. E., Ndesendo, V. M., du Toit, L. C., and Naidoo, D. (2009). Nanotechnological applications for the treatment of neurodegenerative disorders. Prog. Neurobiol. 88, 272-285. doi:10.1016/j.pneurobio.2009.05.002
    • (2009) Prog. Neurobiol , vol.88 , pp. 272-285
    • Modi, G.1    Pillay, V.2    Choonara, Y.E.3    Ndesendo, V.M.4    du Toit, L.C.5    Naidoo, D.6
  • 45
    • 78650300340 scopus 로고    scopus 로고
    • Curcumin-decorated nanoliposomes with very high affinity for amyloid-beta1-42 peptide
    • Mourtas, S., Canovi, M., Zona, C., Aurilia, D., Niarakis, A., La Ferla, B., et al. (2011). Curcumin-decorated nanoliposomes with very high affinity for amyloid-beta1-42 peptide. Biomaterials 32, 1635-1645. doi:10.1016/j.biomaterials.2010.10.027
    • (2011) Biomaterials , vol.32 , pp. 1635-1645
    • Mourtas, S.1    Canovi, M.2    Zona, C.3    Aurilia, D.4    Niarakis, A.5    La Ferla, B.6
  • 46
    • 34547473731 scopus 로고    scopus 로고
    • Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice
    • Muhs, A., Hickman, D. T., Pihlgren, M., Chuard, N., Giriens, V., Meerschman, C., et al. (2007). Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice. Proc. Natl. Acad. Sci. U.S.A. 104, 9810-9815. doi:10.1073/pnas.0703137104
    • (2007) Proc. Natl. Acad. Sci. U.S.A , vol.104 , pp. 9810-9815
    • Muhs, A.1    Hickman, D.T.2    Pihlgren, M.3    Chuard, N.4    Giriens, V.5    Meerschman, C.6
  • 47
    • 84872730067 scopus 로고    scopus 로고
    • Alzheimer's therapeutics: continued clinical failures question the validity of the amyloid hypothesis-but what lies beyond?
    • Mullane, K., and Williams, M. (2013). Alzheimer's therapeutics: continued clinical failures question the validity of the amyloid hypothesis-but what lies beyond? Biochem. Pharmacol. 85, 289-305. doi:10.1016/j.bcp.2012.11.014
    • (2013) Biochem. Pharmacol , vol.85 , pp. 289-305
    • Mullane, K.1    Williams, M.2
  • 48
    • 84888289680 scopus 로고    scopus 로고
    • Trafficking in neurons: searching for new targets for Alzheimer's disease future therapies
    • Musardo, S., Saraceno, C., Pelucchi, S., and Marcello, E. (2013). Trafficking in neurons: searching for new targets for Alzheimer's disease future therapies. Eur. J. Pharmacol. 719, 84-106. doi:10.1016/j.ejphar.2013.07.019
    • (2013) Eur. J. Pharmacol , vol.719 , pp. 84-106
    • Musardo, S.1    Saraceno, C.2    Pelucchi, S.3    Marcello, E.4
  • 49
    • 79958761285 scopus 로고    scopus 로고
    • New perspective for the treatment of Alzheimer diseases: liposomal rivastigmine formulations
    • Mutlu, N. B., Degim, Z., Yilmaz, S., Eiz, D., and Nacar, A. (2011). New perspective for the treatment of Alzheimer diseases: liposomal rivastigmine formulations. Drug Dev. Ind. Pharm. 37, 775-789. doi:10.3109/03639045.2010.541262
    • (2011) Drug Dev. Ind. Pharm , vol.37 , pp. 775-789
    • Mutlu, N.B.1    Degim, Z.2    Yilmaz, S.3    Eiz, D.4    Nacar, A.5
  • 50
    • 69249217640 scopus 로고    scopus 로고
    • Biomaterials for promoting brain protection, repair and regeneration
    • Orive, G., Anitua, E., Pedraz, J. L., and Emerich, D. F. (2009). Biomaterials for promoting brain protection, repair and regeneration. Nat. Rev. Neurosci. 10, 682-692. doi:10.1038/nrn2685
    • (2009) Nat. Rev. Neurosci , vol.10 , pp. 682-692
    • Orive, G.1    Anitua, E.2    Pedraz, J.L.3    Emerich, D.F.4
  • 51
    • 77953483358 scopus 로고    scopus 로고
    • Neuroprotective effect of quercetin encapsulated liposomes: a novel therapeutic strategy against Alzheimer's disease
    • Phachonpai, W., Wattanathorn, J., Muchimapura, S., Tong-Un, T., and Preechagoon, D. (2010). Neuroprotective effect of quercetin encapsulated liposomes: a novel therapeutic strategy against Alzheimer's disease. Am. J. Appl. Sci. 7, 480-485. doi:10.3844/ajassp.2010.480.485
    • (2010) Am. J. Appl. Sci , vol.7 , pp. 480-485
    • Phachonpai, W.1    Wattanathorn, J.2    Muchimapura, S.3    Tong-Un, T.4    Preechagoon, D.5
  • 52
    • 33646473959 scopus 로고    scopus 로고
    • Therapeutic potential of controlled drug delivery systems in neurodegenerative diseases
    • Popovic, N., and Brundin, P. (2006). Therapeutic potential of controlled drug delivery systems in neurodegenerative diseases. Int. J. Pharm. 314, 120-126. doi:10.1016/j.ijpharm.2005.09.040
    • (2006) Int. J. Pharm , vol.314 , pp. 120-126
    • Popovic, N.1    Brundin, P.2
  • 53
    • 0037070606 scopus 로고    scopus 로고
    • Direct interaction of soluble human recombinant tau protein with Abeta 1-42 results in tau aggregation and hyperphosphorylation by tau protein kinase II
    • Ranka, K. B., Pauleya, A. M., Bhattacharyaa, K., Wanga, Z., Evansa, D. B., Flecka, T. J., et al. (2002). Direct interaction of soluble human recombinant tau protein with Abeta 1-42 results in tau aggregation and hyperphosphorylation by tau protein kinase II. FEBS Lett. 514, 263-268. doi:10.1016/S0014-5793(02)02376-1
    • (2002) FEBS Lett , vol.514 , pp. 263-268
    • Ranka, K.B.1    Pauleya, A.M.2    Bhattacharyaa, K.3    Wanga, Z.4    Evansa, D.B.5    Flecka, T.J.6
  • 54
    • 10744224267 scopus 로고    scopus 로고
    • Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Aβ amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial
    • Ritchie, C. W., Bush, A. I., Mackinnon, A., Macfarlane, S., Mastwyk, M., and Tammer, A. (2003). Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Aβ amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Arch. Neurol. 60, 1685-1691. doi:10.1001/archneur.60.12.1685
    • (2003) Arch. Neurol , vol.60 , pp. 1685-1691
    • Ritchie, C.W.1    Bush, A.I.2    Mackinnon, A.3    Macfarlane, S.4    Mastwyk, M.5    Tammer, A.6
  • 55
    • 0031983322 scopus 로고    scopus 로고
    • Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: an interim analysis of the results of a US multicenter open label extension study
    • Rogers, S., and Friedhoff, L. (1998). Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: an interim analysis of the results of a US multicenter open label extension study. Eur. Neuropsychopharmacol. 8, 67-75. doi:10.1016/S0924-977X(97)00079-5
    • (1998) Eur. Neuropsychopharmacol , vol.8 , pp. 67-75
    • Rogers, S.1    Friedhoff, L.2
  • 56
    • 27744599588 scopus 로고    scopus 로고
    • Targeted nanoparticles for drug delivery through the blood-brain barrier for Alzheimer's disease
    • Roney, C., Kulkarni, P., Arora, V., Antich, P., Bonte, F., Wu, A., et al. (2005). Targeted nanoparticles for drug delivery through the blood-brain barrier for Alzheimer's disease. J. Control Release 108, 193-214. doi:10.1016/j.jconrel.2005.07.024
    • (2005) J. Control Release , vol.108 , pp. 193-214
    • Roney, C.1    Kulkarni, P.2    Arora, V.3    Antich, P.4    Bonte, F.5    Wu, A.6
  • 57
    • 49149124343 scopus 로고    scopus 로고
    • Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
    • Shankar, G. M., Li, S., Mehta, T. H., Garcia-Munoz, A., Shepardson, N. E., Smith, I., et al. (2008). Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat. Med. 14, 837-842. doi:10.1038/nm1782
    • (2008) Nat. Med , vol.14 , pp. 837-842
    • Shankar, G.M.1    Li, S.2    Mehta, T.H.3    Garcia-Munoz, A.4    Shepardson, N.E.5    Smith, I.6
  • 58
    • 0034961245 scopus 로고    scopus 로고
    • Liposomal antioxidants in combating ischemia-reperfusion injury in rat brain
    • Sinha, J., Das, N., and Basu, M. K. (2001). Liposomal antioxidants in combating ischemia-reperfusion injury in rat brain. Biomed. Pharmacother. 55, 264-271. doi:10.1016/S0753-3322(01)00060-9
    • (2001) Biomed. Pharmacother , vol.55 , pp. 264-271
    • Sinha, J.1    Das, N.2    Basu, M.K.3
  • 59
    • 84861311174 scopus 로고    scopus 로고
    • Liposomes for targeted delivery of active agents against neurodegenerative diseases (Alzheimer's disease and Parkinson's disease)
    • Spuch, C., and Navarro, C. (2011). Liposomes for targeted delivery of active agents against neurodegenerative diseases (Alzheimer's disease and Parkinson's disease). J. Drug Deliv. 2011, 469679. doi:10.1155/2011/469679
    • (2011) J. Drug Deliv , vol.2011
    • Spuch, C.1    Navarro, C.2
  • 60
    • 84953387445 scopus 로고    scopus 로고
    • Cellular uptake and intracellular degradation of poly(alkyl cyanoacrylate) nanoparticles
    • Sulheim, E., Baghirov, H., von Haartman, E., Boe, A., Aslund, A. K., Morch, Y., et al. (2016). Cellular uptake and intracellular degradation of poly(alkyl cyanoacrylate) nanoparticles. J. Nanobiotechnology. 14, 1. doi:10.1186/s12951-015-0156-7
    • (2016) J. Nanobiotechnology , vol.14 , pp. 1
    • Sulheim, E.1    Baghirov, H.2    von Haartman, E.3    Boe, A.4    Aslund, A.K.5    Morch, Y.6
  • 61
    • 0037728833 scopus 로고    scopus 로고
    • Inhibition of protein phosphatase 2A-and protein phosphatase 1-induced tau hyperphosphorylation and impairment of spatial memory retention in rats
    • Sun, L., Liu, S. Y., Zhou, X. W., Wang, X. C., Liu, R., Wang, Q., et al. (2003). Inhibition of protein phosphatase 2A-and protein phosphatase 1-induced tau hyperphosphorylation and impairment of spatial memory retention in rats. Neuroscience 118, 1175-1182. doi:10.1016/S0306-4522(02)00697-8
    • (2003) Neuroscience , vol.118 , pp. 1175-1182
    • Sun, L.1    Liu, S.Y.2    Zhou, X.W.3    Wang, X.C.4    Liu, R.5    Wang, Q.6
  • 62
    • 84938088147 scopus 로고    scopus 로고
    • Protein aggregation in Alzheimer's disease: a beta and tau and their potential roles in the pathogenesis of AD
    • Thal, D. R., and Fandrich, M. (2015). Protein aggregation in Alzheimer's disease: a beta and tau and their potential roles in the pathogenesis of AD. Acta Neuropathol. 129, 163-165. doi:10.1007/s00401-015-1387-2
    • (2015) Acta Neuropathol , vol.129 , pp. 163-165
    • Thal, D.R.1    Fandrich, M.2
  • 63
    • 57649221135 scopus 로고    scopus 로고
    • Amyloid precursor protein trafficking, processing, and function
    • Thinakaran, G., and Koo, E. H. (2008). Amyloid precursor protein trafficking, processing, and function. J. Biol. Chem. 283, 29615-29619. doi:10.1074/jbc. R800019200
    • (2008) J. Biol. Chem , vol.283 , pp. 29615-29619
    • Thinakaran, G.1    Koo, E.H.2
  • 64
    • 3242740239 scopus 로고    scopus 로고
    • Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration
    • Thorne, R. G., Pronk, G. J., Padmanabhan, V., and Frey, W. H. (2004). Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration. Neuroscience 127, 481-496. doi:10.1016/j.neuroscience.2004.05.029
    • (2004) Neuroscience , vol.127 , pp. 481-496
    • Thorne, R.G.1    Pronk, G.J.2    Padmanabhan, V.3    Frey, W.H.4
  • 65
    • 73849114860 scopus 로고    scopus 로고
    • Intranasal administration of quercetin liposome decreases anxiety-like behaviour and increases spatial memory
    • Wattanathorn, J., Phachonpai, W., Pripem, S., and Suthiparinyanont, S. (2007). Intranasal administration of quercetin liposome decreases anxiety-like behaviour and increases spatial memory. Am. J. Agric. Biol. Sci. 2, 31-33. doi:10.3844/ajabssp.2007.31.35
    • (2007) Am. J. Agric. Biol. Sci , vol.2 , pp. 31-33
    • Wattanathorn, J.1    Phachonpai, W.2    Pripem, S.3    Suthiparinyanont, S.4
  • 66
    • 69249206554 scopus 로고    scopus 로고
    • On the nature of biomaterials
    • Williams, D. F. (2009). On the nature of biomaterials. Biomaterials 30, 5897-5909. doi:10.1016/j.biomaterials.2009.07.027
    • (2009) Biomaterials , vol.30 , pp. 5897-5909
    • Williams, D.F.1
  • 67
    • 68249161435 scopus 로고    scopus 로고
    • Brain targeting PBCA nanoparticles and the blood-brain barrier
    • Wilson, B. (2009). Brain targeting PBCA nanoparticles and the blood-brain barrier. Nanomedicine 4, 499-502. doi:10.2217/nnm.09.29
    • (2009) Nanomedicine , vol.4 , pp. 499-502
    • Wilson, B.1
  • 69
    • 84890299023 scopus 로고    scopus 로고
    • Intranasal nanoparticles of basic fibroblast growth factor for brain delivery to treat Alzheimer's disease
    • Zhang, C., Chen, J., Feng, C., Shao, X., Liu, Q., Zhang, Q., et al. (2014a). Intranasal nanoparticles of basic fibroblast growth factor for brain delivery to treat Alzheimer's disease. Int. J. Pharm. 461, 192-202. doi:10.1016/j.ijpharm.2013.11.049
    • (2014) Int. J. Pharm , vol.461 , pp. 192-202
    • Zhang, C.1    Chen, J.2    Feng, C.3    Shao, X.4    Liu, Q.5    Zhang, Q.6
  • 70
    • 84890128743 scopus 로고    scopus 로고
    • Effects of neural stem cells on synaptic proteins and memory in a mouse model of Alzheimer's disease
    • Zhang, W., Wang, G. M., Wang, P. J., Zhang, Q., and Sha, S. H. (2014b). Effects of neural stem cells on synaptic proteins and memory in a mouse model of Alzheimer's disease. J. Neurosci. Res. 92, 185-194. doi:10.1002/jnr.23299
    • (2014) J. Neurosci. Res , vol.92 , pp. 185-194
    • Zhang, W.1    Wang, G.M.2    Wang, P.J.3    Zhang, Q.4    Sha, S.H.5
  • 71
    • 33846317458 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of donepezil-sustained release microparticles for the treatment of Alzheimer's disease
    • Zhang, P., Chen, L., Gu, W., Xu, Z., Gao, Y., and Li, Y. (2007). In vitro and in vivo evaluation of donepezil-sustained release microparticles for the treatment of Alzheimer's disease. Biomaterials 28, 1882-1888. doi:10.1016/j.biomaterials.2006.12.016
    • (2007) Biomaterials , vol.28 , pp. 1882-1888
    • Zhang, P.1    Chen, L.2    Gu, W.3    Xu, Z.4    Gao, Y.5    Li, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.