-
1
-
-
84906882822
-
Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013
-
Ng M, Fleming T, Robinson M et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2014; 384: 766–781.
-
(2014)
Lancet
, vol.384
, pp. 766-781
-
-
Ng, M.1
Fleming, T.2
Robinson, M.3
-
2
-
-
74549140993
-
Prevalence and trends in obesity among US adults, 1999–2008
-
Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999–2008. JAMA 2010; 303: 235–241.
-
(2010)
JAMA
, vol.303
, pp. 235-241
-
-
Flegal, K.M.1
Carroll, M.D.2
Ogden, C.L.3
Curtin, L.R.4
-
3
-
-
0034630441
-
Overweight, obesity, and health risk
-
National Task Force on the Prevention and Treatment of Obesity. Overweight, obesity, and health risk. Arch Intern Med 2000; 160: 898–904.
-
(2000)
Arch Intern Med
, vol.160
, pp. 898-904
-
-
-
4
-
-
33847013242
-
Health risks associated with overweight and obesity
-
Kopelman P. Health risks associated with overweight and obesity. Obes Rev 2007; 8(Suppl. 1): 13–17.
-
(2007)
Obes Rev
, vol.8
, pp. 13-17
-
-
Kopelman, P.1
-
5
-
-
35848935201
-
Cause-specific excess deaths associated with underweight, overweight, and obesity
-
Flegal KM, Graubard BI, Williamson DF, Gail MH. Cause-specific excess deaths associated with underweight, overweight, and obesity. JAMA 2007; 298: 2028–2037.
-
(2007)
JAMA
, vol.298
, pp. 2028-2037
-
-
Flegal, K.M.1
Graubard, B.I.2
Williamson, D.F.3
Gail, M.H.4
-
6
-
-
84883141056
-
The complex interaction between obesity, metabolic syndrome and reproductive axis: a narrative review
-
Michalakis K, Mintziori G, Kaprara A, Tarlatzis BC, Goulis DG. The complex interaction between obesity, metabolic syndrome and reproductive axis: a narrative review. Metabolism 2013; 62: 457–478.
-
(2013)
Metabolism
, vol.62
, pp. 457-478
-
-
Michalakis, K.1
Mintziori, G.2
Kaprara, A.3
Tarlatzis, B.C.4
Goulis, D.G.5
-
7
-
-
84892476014
-
Diabetes and cancer: two diseases with obesity as a common risk factor
-
Garg SK, Maurer H, Reed K, Selagamsetty R. Diabetes and cancer: two diseases with obesity as a common risk factor. Diabetes Obes Metab 2014; 16: 97–110.
-
(2014)
Diabetes Obes Metab
, vol.16
, pp. 97-110
-
-
Garg, S.K.1
Maurer, H.2
Reed, K.3
Selagamsetty, R.4
-
8
-
-
84904395452
-
Nonalcoholic fatty liver disease and polycystic ovary syndrome
-
Vassilatou E. Nonalcoholic fatty liver disease and polycystic ovary syndrome. World J Gastroenterol 2014; 20: 8351–8363.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 8351-8363
-
-
Vassilatou, E.1
-
9
-
-
75649088159
-
Benefits of moderate weight loss in patients with type 2 diabetes
-
Fujioka K. Benefits of moderate weight loss in patients with type 2 diabetes. Diabetes Obes Metab 2010; 12: 186–194.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 186-194
-
-
Fujioka, K.1
-
10
-
-
79960969194
-
Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes
-
Wing RR, Lang W, Wadden TA et al. Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes. Diabetes Care 2011; 34: 1481–1486.
-
(2011)
Diabetes Care
, vol.34
, pp. 1481-1486
-
-
Wing, R.R.1
Lang, W.2
Wadden, T.A.3
-
11
-
-
84891919414
-
Long-term drug treatment for obesity: a systematic and clinical review
-
Yanovski SZ, Yanovski JA. Long-term drug treatment for obesity: a systematic and clinical review. JAMA 2014; 311: 74–86.
-
(2014)
JAMA
, vol.311
, pp. 74-86
-
-
Yanovski, S.Z.1
Yanovski, J.A.2
-
12
-
-
84940559645
-
Weight management in type 2 diabetes: current and emerging approaches to treatment
-
Van Gaal L, Scheen A. Weight management in type 2 diabetes: current and emerging approaches to treatment. Diabetes Care 2015; 38: 1161–1172.
-
(2015)
Diabetes Care
, vol.38
, pp. 1161-1172
-
-
Van Gaal, L.1
Scheen, A.2
-
13
-
-
84928347829
-
Next generation of weight management medications: implications for diabetes and CVD risk
-
Wharton S, Serodio KJ. Next generation of weight management medications: implications for diabetes and CVD risk. Curr Cardiol Rep 2015; 17: 35.
-
(2015)
Curr Cardiol Rep
, vol.17
, pp. 35
-
-
Wharton, S.1
Serodio, K.J.2
-
14
-
-
84863412995
-
Maintained intentional weight loss reduces cardiovascular outcomes: results from the Sibutramine Cardiovascular OUTcomes (SCOUT) trial
-
Caterson ID, Finer N, Coutinho W et al. Maintained intentional weight loss reduces cardiovascular outcomes: results from the Sibutramine Cardiovascular OUTcomes (SCOUT) trial. Diabetes Obes Metab 2012; 14: 523–530.
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 523-530
-
-
Caterson, I.D.1
Finer, N.2
Coutinho, W.3
-
15
-
-
84924933736
-
New medications for treatment of obesity: metabolic and cardiovascular effects
-
Pucci A, Finer N. New medications for treatment of obesity: metabolic and cardiovascular effects. Can J Cardiol 2015; 31: 142–152.
-
(2015)
Can J Cardiol
, vol.31
, pp. 142-152
-
-
Pucci, A.1
Finer, N.2
-
16
-
-
84906938411
-
Lifelong patterns of BMI and cardiovascular phenotype in individuals aged 60-64 years in the 1946 British birth cohort study: an epidemiological study
-
Charakida M, Khan T, Johnson W et al. Lifelong patterns of BMI and cardiovascular phenotype in individuals aged 60-64 years in the 1946 British birth cohort study: an epidemiological study. Lancet Diabetes Endocrinol 2014; 2: 648–654.
-
(2014)
Lancet Diabetes Endocrinol
, vol.2
, pp. 648-654
-
-
Charakida, M.1
Khan, T.2
Johnson, W.3
-
17
-
-
80052203917
-
Quantification of the effect of energy imbalance on bodyweight
-
Hall KD, Sacks G, Chandramohan D et al. Quantification of the effect of energy imbalance on bodyweight. Lancet 2011; 378: 826–837.
-
(2011)
Lancet
, vol.378
, pp. 826-837
-
-
Hall, K.D.1
Sacks, G.2
Chandramohan, D.3
-
18
-
-
84857873337
-
Lifestyle modification for obesity: new developments in diet, physical activity, and behavior therapy
-
Wadden TA, Webb VL, Moran CH, Bailer BA. Lifestyle modification for obesity: new developments in diet, physical activity, and behavior therapy. Circulation 2012; 125: 1157–1170.
-
(2012)
Circulation
, vol.125
, pp. 1157-1170
-
-
Wadden, T.A.1
Webb, V.L.2
Moran, C.H.3
Bailer, B.A.4
-
19
-
-
65449152558
-
American College of Sports Medicine position stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults
-
Donnelly JE, Blair SN, Jakicic JM et al. American College of Sports Medicine position stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc 2009; 41: 459–471.
-
(2009)
Med Sci Sports Exerc
, vol.41
, pp. 459-471
-
-
Donnelly, J.E.1
Blair, S.N.2
Jakicic, J.M.3
-
20
-
-
84880323061
-
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes
-
Look ARG, Wing RR, Bolin P et al. Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med 2013; 369: 145–154.
-
(2013)
N Engl J Med
, vol.369
, pp. 145-154
-
-
Look, A.R.G.1
Wing, R.R.2
Bolin, P.3
-
21
-
-
84875650236
-
Managing obesity in primary care practice: a narrative review
-
Carvajal R, Wadden TA, Tsai AG, Peck K, Moran CH. Managing obesity in primary care practice: a narrative review. Ann N Y Acad Sci 2013; 1281: 191–206.
-
(2013)
Ann N Y Acad Sci
, vol.1281
, pp. 191-206
-
-
Carvajal, R.1
Wadden, T.A.2
Tsai, A.G.3
Peck, K.4
Moran, C.H.5
-
22
-
-
84907414954
-
Mechanisms of weight regain following weight Loss
-
Blomain ES, Dirhan DA, Valentino MA, Kim GW, Waldman SA. Mechanisms of weight regain following weight Loss. ISRN Obes 2013; 2013: 210524.
-
(2013)
ISRN Obes
, vol.2013
, pp. 210524
-
-
Blomain, E.S.1
Dirhan, D.A.2
Valentino, M.A.3
Kim, G.W.4
Waldman, S.A.5
-
23
-
-
84897891370
-
The effectiveness and risks of bariatric surgery: an updated systematic review and meta-analysis, 2003–2012
-
Chang SH, Stoll CR, Song J, Varela JE, Eagon CJ, Colditz GA. The effectiveness and risks of bariatric surgery: an updated systematic review and meta-analysis, 2003–2012. JAMA Surg 2014; 149: 275–287.
-
(2014)
JAMA Surg
, vol.149
, pp. 275-287
-
-
Chang, S.H.1
Stoll, C.R.2
Song, J.3
Varela, J.E.4
Eagon, C.J.5
Colditz, G.A.6
-
24
-
-
84928829892
-
Systematic review on reoperative bariatric surgery: American Society for Metabolic and Bariatric Surgery Revision Task Force
-
Brethauer SA, Kothari S, Sudan R et al. Systematic review on reoperative bariatric surgery: American Society for Metabolic and Bariatric Surgery Revision Task Force. Surg Obes Relat Dis 2014; 10: 952–972.
-
(2014)
Surg Obes Relat Dis
, vol.10
, pp. 952-972
-
-
Brethauer, S.A.1
Kothari, S.2
Sudan, R.3
-
25
-
-
78649946434
-
[Drug treatment of obesity–current situation and perspectives]
-
[Article in Czech].
-
Hainer V. [Drug treatment of obesity–current situation and perspectives]. Cas Lek Cesk 2010; 149: 513–519 [Article in Czech].
-
(2010)
Cas Lek Cesk
, vol.149
, pp. 513-519
-
-
Hainer, V.1
-
26
-
-
84862582505
-
Anti-obesity drugs: a review about their effects and safety
-
Kang JG, Park CY. Anti-obesity drugs: a review about their effects and safety. Diabetes Metab J 2012; 36: 13–25.
-
(2012)
Diabetes Metab J
, vol.36
, pp. 13-25
-
-
Kang, J.G.1
Park, C.Y.2
-
27
-
-
84860163107
-
Anti-obesity drugs: a review about their effects and their safety
-
Derosa G, Maffioli P. Anti-obesity drugs: a review about their effects and their safety. Expert Opin Drug Saf 2012; 11: 459–471.
-
(2012)
Expert Opin Drug Saf
, vol.11
, pp. 459-471
-
-
Derosa, G.1
Maffioli, P.2
-
29
-
-
84898987526
-
Pharmacotherapy for obesity: novel agents and paradigms
-
Manning S, Pucci A, Finer N. Pharmacotherapy for obesity: novel agents and paradigms. Ther Adv Chronic Dis 2014; 5: 135–148.
-
(2014)
Ther Adv Chronic Dis
, vol.5
, pp. 135-148
-
-
Manning, S.1
Pucci, A.2
Finer, N.3
-
31
-
-
0032511601
-
Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 39
-
UK Prospective Diabetes Study Group. Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 39. BMJ 1998; 317: 713–720.
-
(1998)
BMJ
, vol.317
, pp. 713-720
-
-
-
32
-
-
39749202259
-
Management of type 2 diabetes in the obese patient: current concerns and emerging therapies
-
Krentz AJ. Management of type 2 diabetes in the obese patient: current concerns and emerging therapies. Curr Med Res Opin 2008; 24: 401–417.
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 401-417
-
-
Krentz, A.J.1
-
33
-
-
84901849274
-
Combating the dual burden: therapeutic targeting of common pathways in obesity and type 2 diabetes
-
Scheen AJ, Van Gaal LF. Combating the dual burden: therapeutic targeting of common pathways in obesity and type 2 diabetes. Lancet Diabetes Endocrinol 2014; 2: 911–922.
-
(2014)
Lancet Diabetes Endocrinol
, vol.2
, pp. 911-922
-
-
Scheen, A.J.1
Van Gaal, L.F.2
-
35
-
-
33947678206
-
Thermogenic and metabolic antiobesity drugs: rationale and opportunities
-
Clapham JC, Arch JR. Thermogenic and metabolic antiobesity drugs: rationale and opportunities. Diabetes Obes Metab 2007; 9: 259–275.
-
(2007)
Diabetes Obes Metab
, vol.9
, pp. 259-275
-
-
Clapham, J.C.1
Arch, J.R.2
-
37
-
-
34249743161
-
Dinitrophenol and obesity: an early twentieth-century regulatory dilemma
-
Colman E. Dinitrophenol and obesity: an early twentieth-century regulatory dilemma. Regul Toxicol Pharmacol 2007; 48: 115–117.
-
(2007)
Regul Toxicol Pharmacol
, vol.48
, pp. 115-117
-
-
Colman, E.1
-
38
-
-
84959484123
-
Weight management in obesitypast and present
-
Haslam D. Weight management in obesitypast and present. Int J Clin Pract 2016; 70: 206–217.
-
(2016)
Int J Clin Pract
, vol.70
, pp. 206-217
-
-
Haslam, D.1
-
40
-
-
63249123940
-
Review paper: current strategies in the development of anti-obesity drugs and their safety concerns
-
Elangbam CS. Review paper: current strategies in the development of anti-obesity drugs and their safety concerns. Vet Pathol 2009; 46: 10–24.
-
(2009)
Vet Pathol
, vol.46
, pp. 10-24
-
-
Elangbam, C.S.1
-
41
-
-
84865630915
-
Developing new drugs for diabetes and cardiometabolic disorders: a changing paradigm
-
Krentz AJ, Morrow L, Hompesch M. Developing new drugs for diabetes and cardiometabolic disorders: a changing paradigm. Drugs 2012; 72: 1709–1711.
-
(2012)
Drugs
, vol.72
, pp. 1709-1711
-
-
Krentz, A.J.1
Morrow, L.2
Hompesch, M.3
-
42
-
-
78649922972
-
Drug-induced valvulopathy: an update
-
Elangbam CS. Drug-induced valvulopathy: an update. Toxicol Pathol 2010; 38: 837–848.
-
(2010)
Toxicol Pathol
, vol.38
, pp. 837-848
-
-
Elangbam, C.S.1
-
43
-
-
77952585245
-
-
Available from URL, Accessed 1 October 2015.
-
Food and Drug Administration. Guidance for industry developing products for weight management, 2007. Available from URL: http://www.fda.gov/downloads/Drugs/Guidances/ucm071612.pdf. Accessed 1 October 2015.
-
(2007)
Guidance for industry developing products for weight management
-
-
-
44
-
-
84860330219
-
Food and drug administration's obesity drug guidance document: a short history
-
Colman E. Food and drug administration's obesity drug guidance document: a short history. Circulation 2012; 125: 2156–2164.
-
(2012)
Circulation
, vol.125
, pp. 2156-2164
-
-
Colman, E.1
-
45
-
-
34547669158
-
Drug treatments for obesity: where are we heading and how do we get there?
-
Sonnenberg G, Matfin G, Reinhardt RR. Drug treatments for obesity: where are we heading and how do we get there? Br J Diabetes Vasc Dis 2007; 7: 111–118.
-
(2007)
Br J Diabetes Vasc Dis
, vol.7
, pp. 111-118
-
-
Sonnenberg, G.1
Matfin, G.2
Reinhardt, R.R.3
-
46
-
-
79960692144
-
-
EMA/CHMP/311805/2014. Available from URL, Accessed 1 October 2015.
-
European Medicines Agency. Guideline on clinical evaluation of medicinal products used in weight control, EMA/CHMP/311805/2014. Available from URL: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2014/07/WC500170278.pdf. Accessed 1 October 2015.
-
Guideline on clinical evaluation of medicinal products used in weight control
-
-
-
49
-
-
84913614397
-
Modern obesity pharmacotherapy: weighing cardiovascular risk and benefit
-
Cunningham JW, Wiviott SD. Modern obesity pharmacotherapy: weighing cardiovascular risk and benefit. Clin Cardiol 2014; 37: 693–699.
-
(2014)
Clin Cardiol
, vol.37
, pp. 693-699
-
-
Cunningham, J.W.1
Wiviott, S.D.2
-
50
-
-
85010923198
-
-
Washington DC,, Accessed 1 October 2015.
-
Ferguson C, David S, Divine L et al. The George Washington University, School of Public Health and Health Services, Department of Health Policy. Obesity drug outcome measures. A consensus report of considerations regarding pharmacologic intervention. Washington DC, 2012. Accessed 1 October 2015.
-
(2012)
Obesity drug outcome measures. A consensus report of considerations regarding pharmacologic intervention
-
-
Ferguson, C.1
David, S.2
Divine, L.3
-
51
-
-
84892490445
-
Obesity drug outcome measures: results of a multi-stakeholder critical dialogue
-
Kahan S, Ferguson C, David S, Divine L. Obesity drug outcome measures: results of a multi-stakeholder critical dialogue. Curr Obes Rep 2013; 2: 128–133.
-
(2013)
Curr Obes Rep
, vol.2
, pp. 128-133
-
-
Kahan, S.1
Ferguson, C.2
David, S.3
Divine, L.4
-
53
-
-
70349308687
-
A new glucagon and GLP-1 co-agonist eliminates obesity in rodents
-
Day JW, Ottaway N, Patterson JT et al. A new glucagon and GLP-1 co-agonist eliminates obesity in rodents. Nat Chem Biol 2009; 5: 749–757.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 749-757
-
-
Day, J.W.1
Ottaway, N.2
Patterson, J.T.3
-
54
-
-
27744444882
-
X-PERT: weight reduction with orlistat in obese subjects receiving a mildly or moderately reduced-energy diet: early response to treatment predicts weight maintenance
-
Toplak H, Ziegler O, Keller U et al. X-PERT: weight reduction with orlistat in obese subjects receiving a mildly or moderately reduced-energy diet: early response to treatment predicts weight maintenance. Diabetes Obes Metab 2005; 7: 699–708.
-
(2005)
Diabetes Obes Metab
, vol.7
, pp. 699-708
-
-
Toplak, H.1
Ziegler, O.2
Keller, U.3
-
55
-
-
33646002321
-
Prediction of response to sibutramine therapy in obese non-diabetic and diabetic patients
-
Finer N, Ryan DH, Renz CL, Hewkin AC. Prediction of response to sibutramine therapy in obese non-diabetic and diabetic patients. Diabetes Obes Metab 2006; 8: 206–213.
-
(2006)
Diabetes Obes Metab
, vol.8
, pp. 206-213
-
-
Finer, N.1
Ryan, D.H.2
Renz, C.L.3
Hewkin, A.C.4
-
56
-
-
84891671541
-
The safety and efficacy of lorcaserin in the management of obesity
-
Hess R, Cross LB. The safety and efficacy of lorcaserin in the management of obesity. Postgrad Med 2013; 125: 62–72.
-
(2013)
Postgrad Med
, vol.125
, pp. 62-72
-
-
Hess, R.1
Cross, L.B.2
-
57
-
-
84883752404
-
New options for the treatment of obesity and type 2 diabetes mellitus (narrative review)
-
Henry RR, Chilton R, Garvey WT. New options for the treatment of obesity and type 2 diabetes mellitus (narrative review). J Diabetes Complications 2013; 27: 508–518.
-
(2013)
J Diabetes Complications
, vol.27
, pp. 508-518
-
-
Henry, R.R.1
Chilton, R.2
Garvey, W.T.3
-
58
-
-
84898426835
-
Update on obesity pharmacotherapy
-
Bray GA, Ryan DH. Update on obesity pharmacotherapy. Ann N Y Acad Sci 2014; 1311: 1–13.
-
(2014)
Ann N Y Acad Sci
, vol.1311
, pp. 1-13
-
-
Bray, G.A.1
Ryan, D.H.2
-
59
-
-
84945459858
-
Current and emerging medications for overweight or obesity in people with comorbidities
-
Fujioka K. Current and emerging medications for overweight or obesity in people with comorbidities. Diabetes Obes Metab 2015; 17: 1021–1032.
-
(2015)
Diabetes Obes Metab
, vol.17
, pp. 1021-1032
-
-
Fujioka, K.1
-
60
-
-
84907697527
-
Early weight loss while on lorcaserin, diet and exercise as a predictor of week 52 weight-loss outcomes
-
Smith SR, O'Neil PM, Astrup A et al. Early weight loss while on lorcaserin, diet and exercise as a predictor of week 52 weight-loss outcomes. Obesity (Silver Spring) 2014; 22: 2137–2146.
-
(2014)
Obesity (Silver Spring)
, vol.22
, pp. 2137-2146
-
-
Smith, S.R.1
O'Neil, P.M.2
Astrup, A.3
-
61
-
-
84887239084
-
Targeting hyperglycaemia with anti-obesity drugs: time for a paradigm shift?
-
Krentz AJ, Hompesch M. Targeting hyperglycaemia with anti-obesity drugs: time for a paradigm shift? Drugs 2013; 73: 1649–1651.
-
(2013)
Drugs
, vol.73
, pp. 1649-1651
-
-
Krentz, A.J.1
Hompesch, M.2
-
62
-
-
0035496358
-
Hypertension in obesity
-
Redon J. Hypertension in obesity. Nutr Metab Cardiovasc Dis 2001; 11: 344–353.
-
(2001)
Nutr Metab Cardiovasc Dis
, vol.11
, pp. 344-353
-
-
Redon, J.1
-
63
-
-
6344226830
-
Pathophysiology and treatment of obesity hypertension
-
Wofford MR, Hall JE. Pathophysiology and treatment of obesity hypertension. Curr Pharm Des 2004; 10: 3621–3637.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 3621-3637
-
-
Wofford, M.R.1
Hall, J.E.2
-
64
-
-
84908871564
-
Non-alcoholic fatty liver disease and obesity: biochemical, metabolic and clinical presentations
-
Milic S, Lulic D, Stimac D. Non-alcoholic fatty liver disease and obesity: biochemical, metabolic and clinical presentations. World J Gastroenterol 2014; 20: 9330–9337.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 9330-9337
-
-
Milic, S.1
Lulic, D.2
Stimac, D.3
-
65
-
-
84858629872
-
Drug treatment of obesity in cardiovascular disease
-
Charakida M, Finer N. Drug treatment of obesity in cardiovascular disease. Am J Cardiovasc Drugs 2012; 12: 93–104.
-
(2012)
Am J Cardiovasc Drugs
, vol.12
, pp. 93-104
-
-
Charakida, M.1
Finer, N.2
-
66
-
-
79959230873
-
Pharmacological treatment of obesity in children and adolescents: present and future
-
Iughetti L, China M, Berri R, Predieri B. Pharmacological treatment of obesity in children and adolescents: present and future. J Obes 2011; 2011: 928165.
-
(2011)
J Obes
, vol.2011
, pp. 928165
-
-
Iughetti, L.1
China, M.2
Berri, R.3
Predieri, B.4
-
67
-
-
84900558759
-
Combination phentermine/topiramate for obesity treatment in primary care: a review
-
Xiong GL, Gadde KM. Combination phentermine/topiramate for obesity treatment in primary care: a review. Postgrad Med 2014; 126: 110–116.
-
(2014)
Postgrad Med
, vol.126
, pp. 110-116
-
-
Xiong, G.L.1
Gadde, K.M.2
-
68
-
-
80053469487
-
Using the edmonton obesity staging system to predict mortality in a population-representative cohort of people with overweight and obesity
-
Padwal RS, Pajewski NM, Allison DB, Sharma AM. Using the edmonton obesity staging system to predict mortality in a population-representative cohort of people with overweight and obesity. CMAJ 2011; 183: E1059–E1066.
-
(2011)
CMAJ
, vol.183
, pp. E1059-E1066
-
-
Padwal, R.S.1
Pajewski, N.M.2
Allison, D.B.3
Sharma, A.M.4
-
69
-
-
84867773387
-
The FDA's assessment of two drugs for chronic weight management
-
Colman E, Golden J, Roberts M, Egan A, Weaver J, Rosebraugh C. The FDA's assessment of two drugs for chronic weight management. N Engl J Med 2012; 367: 1577–1579.
-
(2012)
N Engl J Med
, vol.367
, pp. 1577-1579
-
-
Colman, E.1
Golden, J.2
Roberts, M.3
Egan, A.4
Weaver, J.5
Rosebraugh, C.6
-
74
-
-
0035057728
-
Anorectic drugs and pulmonary hypertension from the bedside to the bench
-
Michelakis ED, Weir EK. Anorectic drugs and pulmonary hypertension from the bedside to the bench. Am J Med Sci 2001; 321: 292–299.
-
(2001)
Am J Med Sci
, vol.321
, pp. 292-299
-
-
Michelakis, E.D.1
Weir, E.K.2
-
75
-
-
0033547771
-
Aminorex to fen/phen: an epidemic foretold
-
Fishman AP. Aminorex to fen/phen: an epidemic foretold. Circulation 1999; 99: 156–161.
-
(1999)
Circulation
, vol.99
, pp. 156-161
-
-
Fishman, A.P.1
-
76
-
-
0026518794
-
Long-term weight control study. I (weeks 0 to 34). The enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placebo
-
Weintraub M, Sundaresan PR, Madan M et al. Long-term weight control study. I (weeks 0 to 34). The enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placebo. Clin Pharmacol Ther 1992; 51: 586–594.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 586-594
-
-
Weintraub, M.1
Sundaresan, P.R.2
Madan, M.3
-
77
-
-
0032504983
-
A population-based study of appetite-suppressant drugs and the risk of cardiac-valve regurgitation
-
Jick H, Vasilakis C, Weinrauch LA, Meier CR, Jick SS, Derby LE. A population-based study of appetite-suppressant drugs and the risk of cardiac-valve regurgitation. N Engl J Med 1998; 339: 719–724.
-
(1998)
N Engl J Med
, vol.339
, pp. 719-724
-
-
Jick, H.1
Vasilakis, C.2
Weinrauch, L.A.3
Meier, C.R.4
Jick, S.S.5
Derby, L.E.6
-
78
-
-
0034700436
-
Phenylpropanolamine and the risk of hemorrhagic stroke
-
Kernan WN, Viscoli CM, Brass LM et al. Phenylpropanolamine and the risk of hemorrhagic stroke. N Engl J Med 2000; 343: 1826–1832.
-
(2000)
N Engl J Med
, vol.343
, pp. 1826-1832
-
-
Kernan, W.N.1
Viscoli, C.M.2
Brass, L.M.3
-
79
-
-
0035106314
-
Phenylpropanolamine and stroke: the study, the FDA ruling, the implications
-
13–19, 23.
-
Mersfelder TL. Phenylpropanolamine and stroke: the study, the FDA ruling, the implications. Cleve Clin J Med 2001; 68: 208–219, 13–19, 23.
-
(2001)
Cleve Clin J Med
, vol.68
, pp. 208-219
-
-
Mersfelder, T.L.1
-
80
-
-
0034890568
-
Long-term pharmacotherapy of obesity 2000: a review of efficacy and safety
-
Glazer G. Long-term pharmacotherapy of obesity 2000: a review of efficacy and safety. Arch Intern Med 2001; 161: 1814–1824.
-
(2001)
Arch Intern Med
, vol.161
, pp. 1814-1824
-
-
Glazer, G.1
-
81
-
-
85047695511
-
Pharmacotherapy for obesity: a quantitative analysis of four decades of published randomized clinical trials
-
Haddock CK, Poston WS, Dill PL, Foreyt JP, Ericsson M. Pharmacotherapy for obesity: a quantitative analysis of four decades of published randomized clinical trials. Int J Obes Relat Metab Disord 2002; 26: 262–273.
-
(2002)
Int J Obes Relat Metab Disord
, vol.26
, pp. 262-273
-
-
Haddock, C.K.1
Poston, W.S.2
Dill, P.L.3
Foreyt, J.P.4
Ericsson, M.5
-
82
-
-
67649563560
-
The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation
-
Di Marzo V, Ligresti A, Cristino L. The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation. Int J Obes (Lond) 2009; 33(Suppl. 2): S18–S24.
-
(2009)
Int J Obes (Lond)
, vol.33
, pp. S18-S24
-
-
Di Marzo, V.1
Ligresti, A.2
Cristino, L.3
-
83
-
-
61649095188
-
The role of the endocannabinoid system in lipogenesis and fatty acid metabolism
-
Vettor R, Pagano C. The role of the endocannabinoid system in lipogenesis and fatty acid metabolism. Best Pract Res Clin Endocrinol Metab 2009; 23: 51–63.
-
(2009)
Best Pract Res Clin Endocrinol Metab
, vol.23
, pp. 51-63
-
-
Vettor, R.1
Pagano, C.2
-
84
-
-
61749097782
-
Use of cannabinoid CB1 receptor antagonists for the treatment of metabolic disorders
-
Scheen AJ, Paquot N. Use of cannabinoid CB1 receptor antagonists for the treatment of metabolic disorders. Best Pract Res Clin Endocrinol Metab 2009; 23: 103–116.
-
(2009)
Best Pract Res Clin Endocrinol Metab
, vol.23
, pp. 103-116
-
-
Scheen, A.J.1
Paquot, N.2
-
85
-
-
33645502759
-
The pharmacology of cannabinoid receptors and their ligands: an overview
-
Pertwee RG. The pharmacology of cannabinoid receptors and their ligands: an overview. Int J Obes (Lond) 2006; 30(Suppl. 1): S13–S18.
-
(2006)
Int J Obes (Lond)
, vol.30
, pp. S13-S18
-
-
Pertwee, R.G.1
-
86
-
-
78549281113
-
The neutral cannabinoid CB(1) receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat
-
Cluny NL, Chambers AP, Vemuri VK et al. The neutral cannabinoid CB(1) receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat. Pharmacol Biochem Behav 2011; 97: 537–543.
-
(2011)
Pharmacol Biochem Behav
, vol.97
, pp. 537-543
-
-
Cluny, N.L.1
Chambers, A.P.2
Vemuri, V.K.3
-
87
-
-
78650960433
-
An overview of the metabolic effects of rimonabant in randomized controlled trials: potential for other cannabinoid 1 receptor blockers in obesity
-
Christopoulou FD, Kiortsis DN. An overview of the metabolic effects of rimonabant in randomized controlled trials: potential for other cannabinoid 1 receptor blockers in obesity. J Clin Pharm Ther 2011; 36: 10–18.
-
(2011)
J Clin Pharm Ther
, vol.36
, pp. 10-18
-
-
Christopoulou, F.D.1
Kiortsis, D.N.2
-
88
-
-
84857425784
-
Pharmacotherapies for obesity: past, current, and future therapies
-
Ioannides-Demos LL, Piccenna L, McNeil JJ. Pharmacotherapies for obesity: past, current, and future therapies. J Obes 2011; 2011: 179674.
-
(2011)
J Obes
, vol.2011
, pp. 179674
-
-
Ioannides-Demos, L.L.1
Piccenna, L.2
McNeil, J.J.3
-
90
-
-
36048995288
-
Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials
-
Christensen R, Kristensen PK, Bartels EM, Bliddal H, Astrup A. Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials. Lancet 2007; 370: 1706–1713.
-
(2007)
Lancet
, vol.370
, pp. 1706-1713
-
-
Christensen, R.1
Kristensen, P.K.2
Bartels, E.M.3
Bliddal, H.4
Astrup, A.5
-
91
-
-
77952290161
-
A clinical trial assessing the safety and efficacy of taranabant, a CB1R inverse agonist, in obese and overweight patients: a high-dose study
-
Aronne LJ, Tonstad S, Moreno M et al. A clinical trial assessing the safety and efficacy of taranabant, a CB1R inverse agonist, in obese and overweight patients: a high-dose study. Int J Obes (Lond) 2010; 34: 919–935.
-
(2010)
Int J Obes (Lond)
, vol.34
, pp. 919-935
-
-
Aronne, L.J.1
Tonstad, S.2
Moreno, M.3
-
92
-
-
37449007904
-
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake
-
Addy C, Wright H, Van Laere K et al. The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake. Cell Metab 2008; 7: 68–78.
-
(2008)
Cell Metab
, vol.7
, pp. 68-78
-
-
Addy, C.1
Wright, H.2
Van Laere, K.3
-
93
-
-
77955472298
-
A clinical trial assessing the safety and efficacy of the CB1R inverse agonist taranabant in obese and overweight patients: low-dose study
-
Proietto J, Rissanen A, Harp JB et al. A clinical trial assessing the safety and efficacy of the CB1R inverse agonist taranabant in obese and overweight patients: low-dose study. Int J Obes (Lond) 2010; 34: 1243–1254.
-
(2010)
Int J Obes (Lond)
, vol.34
, pp. 1243-1254
-
-
Proietto, J.1
Rissanen, A.2
Harp, J.B.3
-
94
-
-
84866415138
-
JD-5006 and JD-5037: peripherally restricted (PR) cannabinoid-1 receptor blockers related to SLV-319 (Ibipinabant) as metabolic disorder therapeutics devoid of CNS liabilities
-
Chorvat RJ, Berbaum J, Seriacki K, McElroy JF. JD-5006 and JD-5037: peripherally restricted (PR) cannabinoid-1 receptor blockers related to SLV-319 (Ibipinabant) as metabolic disorder therapeutics devoid of CNS liabilities. Bioorg Med Chem Lett 2012; 22: 6173–6180.
-
(2012)
Bioorg Med Chem Lett
, vol.22
, pp. 6173-6180
-
-
Chorvat, R.J.1
Berbaum, J.2
Seriacki, K.3
McElroy, J.F.4
-
95
-
-
0030993522
-
Sibutramine–a review of clinical efficacy
-
discussion 7–9.
-
Lean ME. Sibutramine–a review of clinical efficacy. Int J Obes Relat Metab Disord 1997; 21(Suppl. 1): S30–S36; discussion 7–9.
-
(1997)
Int J Obes Relat Metab Disord
, vol.21
, pp. S30-S36
-
-
Lean, M.E.1
-
96
-
-
0034289861
-
An assessment of the safety and efficacy of sibutramine, an anti-obesity drug with a novel mechanism of action
-
Nisoli E, Carruba MO. An assessment of the safety and efficacy of sibutramine, an anti-obesity drug with a novel mechanism of action. Obes Rev 2000; 1: 127–139.
-
(2000)
Obes Rev
, vol.1
, pp. 127-139
-
-
Nisoli, E.1
Carruba, M.O.2
-
99
-
-
36849095595
-
Cardiovascular responses to weight management and sibutramine in high-risk subjects: an analysis from the SCOUT trial
-
Torp-Pedersen C, Caterson I, Coutinho W et al. Cardiovascular responses to weight management and sibutramine in high-risk subjects: an analysis from the SCOUT trial. Eur Heart J 2007; 28: 2915–2923.
-
(2007)
Eur Heart J
, vol.28
, pp. 2915-2923
-
-
Torp-Pedersen, C.1
Caterson, I.2
Coutinho, W.3
-
100
-
-
77957292772
-
Cardiovascular risk-benefit profile of sibutramine
-
Scheen AJ. Cardiovascular risk-benefit profile of sibutramine. Am J Cardiovasc Drugs 2010; 10: 321–334.
-
(2010)
Am J Cardiovasc Drugs
, vol.10
, pp. 321-334
-
-
Scheen, A.J.1
-
101
-
-
77956284607
-
Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects
-
James WP, Caterson ID, Coutinho W et al. Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N Engl J Med 2010; 363: 905–917.
-
(2010)
N Engl J Med
, vol.363
, pp. 905-917
-
-
James, W.P.1
Caterson, I.D.2
Coutinho, W.3
-
102
-
-
77954633777
-
Drug management of obesity–efficacy versus safety
-
Astrup A. Drug management of obesity–efficacy versus safety. N Engl J Med 2010; 363: 288–290.
-
(2010)
N Engl J Med
, vol.363
, pp. 288-290
-
-
Astrup, A.1
-
103
-
-
80052487982
-
Is there a path for approval of an antiobesity drug: what did the Sibutramine Cardiovascular Outcomes Trial find?
-
Downey M, Still C, Sharma AM. Is there a path for approval of an antiobesity drug: what did the Sibutramine Cardiovascular Outcomes Trial find? Curr Opin Endocrinol Diabetes Obes 2011; 18: 321–327.
-
(2011)
Curr Opin Endocrinol Diabetes Obes
, vol.18
, pp. 321-327
-
-
Downey, M.1
Still, C.2
Sharma, A.M.3
-
104
-
-
0032752435
-
Orlistat: a review of its use in the management of obesity
-
Hvizdos KM, Markham A. Orlistat: a review of its use in the management of obesity. Drugs 1999; 58: 743–760.
-
(1999)
Drugs
, vol.58
, pp. 743-760
-
-
Hvizdos, K.M.1
Markham, A.2
-
105
-
-
37549037023
-
Orlistat-associated adverse effects and drug interactions: a critical review
-
Filippatos TD, Derdemezis CS, Gazi IF, Nakou ES, Mikhailidis DP, Elisaf MS. Orlistat-associated adverse effects and drug interactions: a critical review. Drug Saf 2008; 31: 53–65.
-
(2008)
Drug Saf
, vol.31
, pp. 53-65
-
-
Filippatos, T.D.1
Derdemezis, C.S.2
Gazi, I.F.3
Nakou, E.S.4
Mikhailidis, D.P.5
Elisaf, M.S.6
-
106
-
-
84862674296
-
Effect of anti-obesity drug on cardiovascular risk factors: a systematic review and meta-analysis of randomized controlled trials
-
Zhou YH, Ma XQ, Wu C et al. Effect of anti-obesity drug on cardiovascular risk factors: a systematic review and meta-analysis of randomized controlled trials. PLoS One 2012; 7: e39062.
-
(2012)
PLoS One
, vol.7
-
-
Zhou, Y.H.1
Ma, X.Q.2
Wu, C.3
-
109
-
-
84877624422
-
Orlistat and the risk of acute liver injury: self controlled case series study in UK Clinical Practice Research Datalink
-
Douglas IJ, Langham J, Bhaskaran K, Brauer R, Smeeth L. Orlistat and the risk of acute liver injury: self controlled case series study in UK Clinical Practice Research Datalink. BMJ 2013; 346: f1936.
-
(2013)
BMJ
, vol.346
, pp. f1936
-
-
Douglas, I.J.1
Langham, J.2
Bhaskaran, K.3
Brauer, R.4
Smeeth, L.5
-
110
-
-
84877606571
-
Orlistat: should we worry about liver inflammation?
-
Wilding J. Orlistat: should we worry about liver inflammation? BMJ 2013; 346: f2777.
-
(2013)
BMJ
, vol.346
, pp. f2777
-
-
Wilding, J.1
-
111
-
-
33646483917
-
A double-blind randomized placebo-controlled trial of orlistat for the treatment of nonalcoholic fatty liver disease
-
Zelber-Sagi S, Kessler A, Brazowsky E et al. A double-blind randomized placebo-controlled trial of orlistat for the treatment of nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol 2006; 4: 639–644.
-
(2006)
Clin Gastroenterol Hepatol
, vol.4
, pp. 639-644
-
-
Zelber-Sagi, S.1
Kessler, A.2
Brazowsky, E.3
-
112
-
-
79958846395
-
Benfluorex: analysis of a drug-related public health crisis
-
Menard J. Benfluorex: analysis of a drug-related public health crisis. Diabetes Metab 2011; 37: 169–175.
-
(2011)
Diabetes Metab
, vol.37
, pp. 169-175
-
-
Menard, J.1
-
113
-
-
61649119330
-
Fenfluramine-like cardiovascular side-effects of benfluorex
-
Boutet K, Frachon I, Jobic Y et al. Fenfluramine-like cardiovascular side-effects of benfluorex. Eur Respir J 2009; 33: 684–688.
-
(2009)
Eur Respir J
, vol.33
, pp. 684-688
-
-
Boutet, K.1
Frachon, I.2
Jobic, Y.3
-
114
-
-
84868541077
-
Pulmonary hypertension associated with benfluorex exposure
-
Savale L, Chaumais MC, Cottin V et al. Pulmonary hypertension associated with benfluorex exposure. Eur Respir J 2012; 40: 1164–1172.
-
(2012)
Eur Respir J
, vol.40
, pp. 1164-1172
-
-
Savale, L.1
Chaumais, M.C.2
Cottin, V.3
-
115
-
-
79952481679
-
Mediator scandal rocks French medical community
-
Mullard A. Mediator scandal rocks French medical community. Lancet 2011; 377: 890–892.
-
(2011)
Lancet
, vol.377
, pp. 890-892
-
-
Mullard, A.1
-
116
-
-
84879076972
-
Drug-induced valvular heart disease: an update
-
Andrejak M, Tribouilloy C. Drug-induced valvular heart disease: an update. Arch Cardiovasc Dis 2013; 106: 333–339.
-
(2013)
Arch Cardiovasc Dis
, vol.106
, pp. 333-339
-
-
Andrejak, M.1
Tribouilloy, C.2
-
117
-
-
84903781242
-
Adverse effects of benfluorex on heart valves and pulmonary circulation
-
Szymanski C, Andrejak M, Peltier M, Marechaux S, Tribouilloy C. Adverse effects of benfluorex on heart valves and pulmonary circulation. Pharmacoepidemiol Drug Saf 2014; 23: 679–686.
-
(2014)
Pharmacoepidemiol Drug Saf
, vol.23
, pp. 679-686
-
-
Szymanski, C.1
Andrejak, M.2
Peltier, M.3
Marechaux, S.4
Tribouilloy, C.5
-
118
-
-
84862534255
-
Echocardiographic evidence for valvular toxicity of benfluorex: a double-blind randomised trial in patients with type 2 diabetes mellitus
-
Derumeaux G, Ernande L, Serusclat A et al. Echocardiographic evidence for valvular toxicity of benfluorex: a double-blind randomised trial in patients with type 2 diabetes mellitus. PLoS One 2012; 7: e38273.
-
(2012)
PLoS One
, vol.7
-
-
Derumeaux, G.1
Ernande, L.2
Serusclat, A.3
-
119
-
-
85011005640
-
Benfluorex and mortality: a fresh perspective
-
Available from URL, Accessed dd mm yyyy.
-
Harvey N, Judge A. Benfluorex and mortality: a fresh perspective. Epidem Res Int 2013. Available from URL: http://dxdoiorg/101155/2013/490309. Accessed dd mm yyyy.
-
(2013)
Epidem Res Int
-
-
Harvey, N.1
Judge, A.2
-
121
-
-
84875819284
-
-
London, European Medicines Agency, Availablefrom URL, Accessed 1 November 2015.
-
European Medicines Agency. Refusal of the Marketing Authorisation for Qsiva (phentermine/topiramate), London: European Medicines Agency, 2012. Availablefrom URL: http://www.ema.europa.eu/docs/en_GB/document_library/Summary_of_opinion_-_Initial_authorisation/human/002350/WC500134085.pdf Accessed 1 November 2015.
-
(2012)
Refusal of the Marketing Authorisation for Qsiva (phentermine/topiramate)
-
-
-
122
-
-
67649379367
-
Serotonergic drugs and valvular heart disease
-
Rothman RB, Baumann MH. Serotonergic drugs and valvular heart disease. Expert Opin Drug Saf 2009; 8: 317–329.
-
(2009)
Expert Opin Drug Saf
, vol.8
, pp. 317-329
-
-
Rothman, R.B.1
Baumann, M.H.2
-
123
-
-
84880792594
-
Combination therapy with naltrexone and bupropion for obesity reduces total and visceral adiposity
-
Smith SR, Fujioka K, Gupta AK et al. Combination therapy with naltrexone and bupropion for obesity reduces total and visceral adiposity. Diabetes Obes Metab 2013; 15: 863–866.
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 863-866
-
-
Smith, S.R.1
Fujioka, K.2
Gupta, A.K.3
-
124
-
-
77956057548
-
Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
-
Greenway FL, Fujioka K, Plodkowski RA et al. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. Lancet 2010; 376: 595–605.
-
(2010)
Lancet
, vol.376
, pp. 595-605
-
-
Greenway, F.L.1
Fujioka, K.2
Plodkowski, R.A.3
-
125
-
-
79952752855
-
Regulation of appetite to treat obesity
-
Kim GW, Lin JE, Valentino MA, Colon-Gonzalez F, Waldman SA. Regulation of appetite to treat obesity. Exp Rev Clin Pharmacol 2011; 4: 243–259.
-
(2011)
Exp Rev Clin Pharmacol
, vol.4
, pp. 243-259
-
-
Kim, G.W.1
Lin, J.E.2
Valentino, M.A.3
Colon-Gonzalez, F.4
Waldman, S.A.5
-
126
-
-
84891869792
-
Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes
-
Hollander P, Gupta AK, Plodkowski R et al. Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes. Diabetes Care 2013; 36: 4022–4029.
-
(2013)
Diabetes Care
, vol.36
, pp. 4022-4029
-
-
Hollander, P.1
Gupta, A.K.2
Plodkowski, R.3
-
128
-
-
70350619609
-
Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study
-
Astrup A, Rossner S, Van Gaal L et al. Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study. Lancet 2009; 374: 1606–1616.
-
(2009)
Lancet
, vol.374
, pp. 1606-1616
-
-
Astrup, A.1
Rossner, S.2
Van Gaal, L.3
-
129
-
-
84862207266
-
Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide
-
Astrup A, Carraro R, Finer N et al. Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide. Int J Obes (Lond) 2012; 36: 843–854.
-
(2012)
Int J Obes (Lond)
, vol.36
, pp. 843-854
-
-
Astrup, A.1
Carraro, R.2
Finer, N.3
-
130
-
-
84899906592
-
Tolerability of nausea and vomiting and associations with weight loss in a randomized trial of liraglutide in obese, non-diabetic adults
-
Lean ME, Carraro R, Finer N et al. Tolerability of nausea and vomiting and associations with weight loss in a randomized trial of liraglutide in obese, non-diabetic adults. Int J Obes (Lond) 2014; 38: 689–697.
-
(2014)
Int J Obes (Lond)
, vol.38
, pp. 689-697
-
-
Lean, M.E.1
Carraro, R.2
Finer, N.3
-
131
-
-
84887840117
-
Weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight loss: the SCALE Maintenance randomized study
-
Wadden TA, Hollander P, Klein S et al. Weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight loss: the SCALE Maintenance randomized study. Int J Obes (Lond) 2013; 37: 1443–1451.
-
(2013)
Int J Obes (Lond)
, vol.37
, pp. 1443-1451
-
-
Wadden, T.A.1
Hollander, P.2
Klein, S.3
-
132
-
-
84896731936
-
Pancreatic safety of incretin-based drugs–FDA and EMA assessment
-
Egan AG, Blind E, Dunder K et al. Pancreatic safety of incretin-based drugs–FDA and EMA assessment. N Engl J Med 2014; 370: 794–797.
-
(2014)
N Engl J Med
, vol.370
, pp. 794-797
-
-
Egan, A.G.1
Blind, E.2
Dunder, K.3
-
133
-
-
85010994774
-
-
Available from, Accessed 1 November
-
Liraglutide 3.0 mg for Weight Management Briefing Document. Available from URL: http://www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials/drugs/endocrinologicandmetabolicdrugsadvisorycommittee/ucm413318.pdf Accessed 1 November 2015.
-
(2015)
Liraglutide 3.0 mg for Weight Management Briefing Document
-
-
-
134
-
-
84873554686
-
Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis
-
Robinson LE, Holt TA, Rees K, Randeva HS, O'Hare JP. Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis. BMJ Open 2013; 3:e001986.
-
(2013)
BMJ Open
, vol.3
-
-
Robinson, L.E.1
Holt, T.A.2
Rees, K.3
Randeva, H.S.4
O'Hare, J.P.5
-
135
-
-
84886946727
-
Design of the liraglutide effect and action in diabetes: evaluation of cardiovascular outcome results (LEADER) trial
-
Marso SP, Poulter NR, Nissen SE et al. Design of the liraglutide effect and action in diabetes: evaluation of cardiovascular outcome results (LEADER) trial. Am Heart J 2013; 166: 823–830.e5.
-
(2013)
Am Heart J
, vol.166
, pp. 823-830.e5
-
-
Marso, S.P.1
Poulter, N.R.2
Nissen, S.E.3
-
136
-
-
84936166069
-
A randomized, controlled trial of 3.0 mg of liraglutide in weight management
-
Pi-Sunyer X, Astrup A, Fujioka K et al. A randomized, controlled trial of 3.0 mg of liraglutide in weight management. N Engl J Med 2015; 373: 11–22.
-
(2015)
N Engl J Med
, vol.373
, pp. 11-22
-
-
Pi-Sunyer, X.1
Astrup, A.2
Fujioka, K.3
-
137
-
-
84930929005
-
Anti-obesity pharmacotherapy: the intercontinental regulatory divide
-
Krentz AJ, Fujioka K, Hompesch M. Anti-obesity pharmacotherapy: the intercontinental regulatory divide. Drugs 2015; 75: 931–933.
-
(2015)
Drugs
, vol.75
, pp. 931-933
-
-
Krentz, A.J.1
Fujioka, K.2
Hompesch, M.3
-
138
-
-
84884189792
-
When EMA and FDA decisions conflict: differences in patients or in regulation?
-
Wolfe SM. When EMA and FDA decisions conflict: differences in patients or in regulation? BMJ 2013; 347: f5140.
-
(2013)
BMJ
, vol.347
, pp. f5140
-
-
Wolfe, S.M.1
-
140
-
-
84930928930
-
The new era of drug therapy for obesity: the evidence and the expectations
-
Jones BJ, Bloom SR. The new era of drug therapy for obesity: the evidence and the expectations. Drugs 2015; 75: 935–945.
-
(2015)
Drugs
, vol.75
, pp. 935-945
-
-
Jones, B.J.1
Bloom, S.R.2
-
141
-
-
84908241953
-
Thermogenic adipocytes: from cells to physiology and medicine
-
Diaz MB, Herzig S, Vegiopoulos A. Thermogenic adipocytes: from cells to physiology and medicine. Metabolism 2014; 63: 1238–1249.
-
(2014)
Metabolism
, vol.63
, pp. 1238-1249
-
-
Diaz, M.B.1
Herzig, S.2
Vegiopoulos, A.3
-
142
-
-
0037066575
-
Beta(3)-Adrenoceptor agonists: potential, pitfalls and progress
-
Arch JR. Beta(3)-Adrenoceptor agonists: potential, pitfalls and progress. Eur J Pharmacol 2002; 440: 99–107.
-
(2002)
Eur J Pharmacol
, vol.440
, pp. 99-107
-
-
Arch, J.R.1
-
143
-
-
84920627180
-
Activation of human brown adipose tissue by a beta3-adrenergic receptor agonist
-
Cypess AM, Weiner LS, Roberts-Toler C et al. Activation of human brown adipose tissue by a beta3-adrenergic receptor agonist. Cell Metab 2015; 21: 33–38.
-
(2015)
Cell Metab
, vol.21
, pp. 33-38
-
-
Cypess, A.M.1
Weiner, L.S.2
Roberts-Toler, C.3
-
144
-
-
84926226439
-
A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis
-
Hsiao WC, Shia KS, Wang YT et al. A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis. Diabetes Obes Metab 2015; 17: 495–504.
-
(2015)
Diabetes Obes Metab
, vol.17
, pp. 495-504
-
-
Hsiao, W.C.1
Shia, K.S.2
Wang, Y.T.3
-
145
-
-
84910124802
-
Novel mathematical models for investigating topics in obesity
-
Dawson JA, Hall KD, Thomas DM, Hardin JW, Allison DB, Heymsfield SB. Novel mathematical models for investigating topics in obesity. Adv Nutr 2014; 5: 561–562.
-
(2014)
Adv Nutr
, vol.5
, pp. 561-562
-
-
Dawson, J.A.1
Hall, K.D.2
Thomas, D.M.3
Hardin, J.W.4
Allison, D.B.5
Heymsfield, S.B.6
-
146
-
-
84928923102
-
Predicting successful long-term weight loss from short-term weight-loss outcomes: new insights from a dynamic energy balance model (the POUNDS Lost study)
-
Thomas DM, Ivanescu AE, Martin CK et al. Predicting successful long-term weight loss from short-term weight-loss outcomes: new insights from a dynamic energy balance model (the POUNDS Lost study). Am J Clin Nutr 2015; 101: 449–454.
-
(2015)
Am J Clin Nutr
, vol.101
, pp. 449-454
-
-
Thomas, D.M.1
Ivanescu, A.E.2
Martin, C.K.3
-
147
-
-
84928104942
-
Safety and tolerability of medications approved for chronic weight management
-
Fujioka K. Safety and tolerability of medications approved for chronic weight management. Obesity (Silver Spring) 2015; 23(Suppl. 1): S7–S11.
-
(2015)
Obesity (Silver Spring)
, vol.23
, pp. S7-S11
-
-
Fujioka, K.1
|