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Volumn 20, Issue 28, 2014, Pages 9330-9337

Non-alcoholic fatty liver disease and obesity: Biochemical, metabolic and clinical presentations

Author keywords

Fatty liver; Insulin resistance; Intra abdominal fat; Metabolism; Non alcoholic fatty liver disease; Obesity

Indexed keywords

ADIPOCYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN;

EID: 84908871564     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v20.i28.9330     Document Type: Article
Times cited : (396)

References (101)
  • 1
    • 84877247095 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease, diabetes mellitus and cardiovascular disease: Newer data
    • [PMID: 23653642]
    • Mavrogiannaki AN, Migdalis IN. Nonalcoholic Fatty liver disease, diabetes mellitus and cardiovascular disease: newer data. Int J Endocrinol 2013; 2013: 450639 [PMID: 23653642 DOI: 10.1155/2013/450639]
    • (2013) Int J Endocrinol , vol.2013 , pp. 450639
    • Mavrogiannaki, A.N.1    Migdalis, I.N.2
  • 2
    • 84862883948 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease/steatohepatitis: Epidemiology, pathogenesis, clinical presentation and treatment
    • [PMID: 22722431]
    • Milić S, Stimac D. Nonalcoholic fatty liver disease/steatohepatitis: epidemiology, pathogenesis, clinical presentation and treatment. Dig Dis 2012; 30: 158-162 [PMID: 22722431 DOI: 10.1159/000336669]
    • (2012) Dig Dis , vol.30 , pp. 158-162
    • Milić, S.1    Stimac, D.2
  • 3
    • 68049142588 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease pathogenesis: The present and the future
    • [PMID: 19223251]
    • Petta S, Muratore C, Craxì A. Non-alcoholic fatty liver disease pathogenesis: the present and the future. Dig Liver Dis 2009; 41: 615-625 [PMID: 19223251 DOI: 10.1016/j.dld.2009.01.004]
    • (2009) Dig Liver Dis , vol.41 , pp. 615-625
    • Petta, S.1    Muratore, C.2    Craxì, A.3
  • 6
    • 84869436442 scopus 로고    scopus 로고
    • Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review
    • [PMID: 23041539]
    • White DL, Kanwal F, El-Serag HB. Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review. Clin Gastroenterol Hepatol 2012; 10: 1342-1359.e2 [PMID: 23041539 DOI: 10.1016/j.cgh.2012.10.00]
    • (2012) Clin Gastroenterol Hepatol , vol.10 , pp. 1342-1359
    • White, D.L.1    Kanwal, F.2    El-Serag, H.B.3
  • 7
    • 0033019013 scopus 로고    scopus 로고
    • Cryptogenic cirrhosis: Clinical characterization and risk factors for underlying disease
    • [PMID: 10051466]
    • Caldwell SH, Oelsner DH, Iezzoni JC, Hespenheide EE, Battle EH, Driscoll CJ. Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease. Hepatology 1999; 29: 664-669 [PMID: 10051466 DOI: 10.1002/hep.510290347]
    • (1999) Hepatology , vol.29 , pp. 664-669
    • Caldwell, S.H.1    Oelsner, D.H.2    Iezzoni, J.C.3    Hespenheide, E.E.4    Battle, E.H.5    Driscoll, C.J.6
  • 8
    • 84859393575 scopus 로고    scopus 로고
    • Prevalence of prediabetes and diabetes and metabolic profile of patients with nonalcoholic fatty liver disease (NAFLD)
    • [PMID: 22374640]
    • Ortiz-Lopez C, Lomonaco R, Orsak B, Finch J, Chang Z, Kochunov VG, Hardies J, Cusi K. Prevalence of prediabetes and diabetes and metabolic profile of patients with nonalcoholic fatty liver disease (NAFLD). Diabetes Care 2012; 35: 873-878 [PMID: 22374640 DOI: 10.2337/dc11-1849]
    • (2012) Diabetes Care , vol.35 , pp. 873-878
    • Ortiz-Lopez, C.1    Lomonaco, R.2    Orsak, B.3    Finch, J.4    Chang, Z.5    Kochunov, V.G.6    Hardies, J.7    Cusi, K.8
  • 9
    • 84859448472 scopus 로고    scopus 로고
    • Metabolic syndrome and risk factors for non-alcoholic fatty liver disease
    • [PMID: 22481692]
    • Souza MR, Diniz Mde F, Medeiros-Filho JE, Araújo MS. Metabolic syndrome and risk factors for non-alcoholic fatty liver disease. Arq Gastroenterol 2012; 49: 89-96 [PMID: 22481692 DOI: 10.1590/S0004-28032012000100015]
    • (2012) Arq Gastroenterol , vol.49 , pp. 89-96
    • Souza, M.R.1    Diniz Mde, F.2    Medeiros-Filho, J.E.3    Araújo, M.S.4
  • 10
    • 84878930738 scopus 로고    scopus 로고
    • Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
    • [PMID: 23507799]
    • Anstee QM, Targher G, Day CP. Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis. Nat Rev Gastroenterol Hepatol 2013; 10: 330-344 [PMID: 23507799 DOI: 10.1038/nrgastro.2013.41]
    • (2013) Nat Rev Gastroenterol Hepatol , vol.10 , pp. 330-344
    • Anstee, Q.M.1    Targher, G.2    Day, C.P.3
  • 11
    • 84881232944 scopus 로고    scopus 로고
    • Cardiovascular and systemic risk in nonalcoholic fatty liver disease - Atherosclerosis as a major player in the natural course of NAFLD
    • [PMID: 23432668]
    • Lonardo A, Sookoian S, Chonchol M, Loria P, Targher G. Cardiovascular and systemic risk in nonalcoholic fatty liver disease - atherosclerosis as a major player in the natural course of NAFLD. Curr Pharm Des 2013; 19: 5177-5192 [PMID: 23432668 DOI: 10.2174/13816128130301]
    • (2013) Curr Pharm des , vol.19 , pp. 5177-5192
    • Lonardo, A.1    Sookoian, S.2    Chonchol, M.3    Loria, P.4    Targher, G.5
  • 13
    • 67649882494 scopus 로고    scopus 로고
    • Endocrine and liver interaction: The role of endocrine pathways in NASH
    • [PMID: 19347015]
    • Loria P, Carulli L, Bertolotti M, Lonardo A. Endocrine and liver interaction: the role of endocrine pathways in NASH. Nat Rev Gastroenterol Hepatol 2009; 6: 236-247 [PMID: 19347015 DOI: 10.1038/nrgastro.2009.33]
    • (2009) Nat Rev Gastroenterol Hepatol , vol.6 , pp. 236-247
    • Loria, P.1    Carulli, L.2    Bertolotti, M.3    Lonardo, A.4
  • 14
    • 79960029926 scopus 로고    scopus 로고
    • Systematic review: The epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults
    • [PMID: 21623852]
    • Vernon G, Baranova A, Younossi ZM. Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Aliment Pharmacol Ther 2011; 34: 274-285 [PMID: 21623852 DOI: 10.1111/j.1365-2036.2011.04724.x]
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 274-285
    • Vernon, G.1    Baranova, A.2    Younossi, Z.M.3
  • 15
    • 84876526683 scopus 로고    scopus 로고
    • The impact of bariatric surgery on psychological health
    • [PMID: 23606952]
    • Kubik JF, Gill RS, Laffin M, Karmali S. The impact of bariatric surgery on psychological health. J Obes 2013; 2013: 837989 [PMID: 23606952 DOI: 10.1155/2013/83798]
    • (2013) J Obes , vol.2013 , pp. 837989
    • Kubik, J.F.1    Gill, R.S.2    Laffin, M.3    Karmali, S.4
  • 16
    • 0034569866 scopus 로고    scopus 로고
    • Report of a WHO consultation
    • 1-253 [PMID: 11234459]
    • Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser 2000; 894: i-xii, 1-253 [PMID: 11234459]
    • (2000) World Health Organ Tech Rep ser , vol.894 , pp. i-xii
  • 17
    • 79951558318 scopus 로고    scopus 로고
    • National, regional, and global trends in body-mass index since 1980: Systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants
    • [PMID: 21295846]
    • Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, Farzadfar F, Riley LM, Ezzati M. National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants. Lancet 2011; 377: 557-567 [PMID: 21295846 DOI: 10.1016/S0140-6736(10)62037-5]
    • (2011) Lancet , vol.377 , pp. 557-567
    • Finucane, M.M.1    Stevens, G.A.2    Cowan, M.J.3    Danaei, G.4    Lin, J.K.5    Paciorek, C.J.6    Singh, G.M.7    Gutierrez, H.R.8    Lu, Y.9    Bahalim, A.N.10    Farzadfar, F.11    Riley, L.M.12    Ezzati, M.13
  • 18
  • 19
    • 0345447504 scopus 로고    scopus 로고
    • Prevalence and correlates of overweight and obesity among older adults: Findings from the Canadian National Population Health Survey
    • [PMID: 14630884]
    • Kaplan MS, Huguet N, Newsom JT, McFarland BH, Lindsay J. Prevalence and correlates of overweight and obesity among older adults: findings from the Canadian National Population Health Survey. J Gerontol A Biol Sci Med Sci 2003; 58: 1018-1030 [PMID: 14630884 DOI: 10.1093/gerona/58.11. M1018]
    • (2003) J Gerontol A Biol Sci Med Sci , vol.58 , pp. 1018-1030
    • Kaplan, M.S.1    Huguet, N.2    Newsom, J.T.3    McFarland, B.H.4    Lindsay, J.5
  • 20
    • 84858701950 scopus 로고    scopus 로고
    • The interaction of hepatic lipid and glucose metabolism in liver diseases
    • [PMID: 22173168]
    • Bechmann LP, Hannivoort RA, Gerken G, Hotamisligil GS, Trauner M, Canbay A. The interaction of hepatic lipid and glucose metabolism in liver diseases. J Hepatol 2012; 56: 952-964 [PMID: 22173168 DOI: 10.1016/j.jhep.2011.08.025]
    • (2012) J Hepatol , vol.56 , pp. 952-964
    • Bechmann, L.P.1    Hannivoort, R.A.2    Gerken, G.3    Hotamisligil, G.S.4    Trauner, M.5    Canbay, A.6
  • 21
    • 78650486196 scopus 로고    scopus 로고
    • Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: A prospective study
    • [PMID: 20858492]
    • Williams CD, Stengel J, Asike MI, Torres DM, Shaw J, Contreras M, Landt CL, Harrison SA. Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study. Gastroenterology 2011; 140: 124-131 [PMID: 20858492 DOI: 10.1053/j.gastro.2010.09.038]
    • (2011) Gastroenterology , vol.140 , pp. 124-131
    • Williams, C.D.1    Stengel, J.2    Asike, M.I.3    Torres, D.M.4    Shaw, J.5    Contreras, M.6    Landt, C.L.7    Harrison, S.A.8
  • 24
    • 0942268772 scopus 로고    scopus 로고
    • Insulin resistance and ferritin as major determinants of nonalcoholic fatty liver disease in apparently healthy obese patients
    • [PMID: 14610526]
    • Hsiao TJ, Chen JC, Wang JD. Insulin resistance and ferritin as major determinants of nonalcoholic fatty liver disease in apparently healthy obese patients. Int J Obes Relat Metab Disord 2004; 28: 167-172 [PMID: 14610526 DOI: 10.1038/sj.ijo.0802519]
    • (2004) Int J Obes Relat Metab Disord , vol.28 , pp. 167-172
    • Hsiao, T.J.1    Chen, J.C.2    Wang, J.D.3
  • 28
    • 80052840577 scopus 로고    scopus 로고
    • The metabolically benign and malignant fatty liver
    • [PMID: 21788578]
    • Stefan N, Häring HU. The metabolically benign and malignant fatty liver. Diabetes 2011; 60: 2011-2017 [PMID: 21788578 DOI: 10.2337/db11-0231]
    • (2011) Diabetes , vol.60 , pp. 2011-2017
    • Stefan, N.1    Häring, H.U.2
  • 29
    • 77958546532 scopus 로고    scopus 로고
    • Obesity affects the liver - The link between adipocytes and hepatocytes
    • [PMID: 21042023]
    • Wree A, Kahraman A, Gerken G, Canbay A. Obesity affects the liver - the link between adipocytes and hepatocytes. Digestion 2011; 83: 124-133 [PMID: 21042023 DOI: 10.1159/000318741]
    • (2011) Digestion , vol.83 , pp. 124-133
    • Wree, A.1    Kahraman, A.2    Gerken, G.3    Canbay, A.4
  • 30
    • 77952517940 scopus 로고    scopus 로고
    • Clinical physiology of NAFLD: A critical overview of pathogenesis and treatment
    • Lonardo A, Caldwell SH, Loria P. Clinical physiology of NAFLD: a critical overview of pathogenesis and treatment. Expert Rev Endocrinol Metab 2010; 5: 403-423 [DOI: 10.1586/eem.10.5]
    • (2010) Expert Rev Endocrinol Metab , vol.5 , pp. 403-423
    • Lonardo, A.1    Caldwell, S.H.2    Loria, P.3
  • 31
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
    • [PMID: 15685173]
    • Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med 2005; 11: 183-190 [PMID: 15685173 DOI: 10.1038/nm1166]
    • (2005) Nat Med , vol.11 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3    Melendez, P.A.4    Hansen, L.5    Lee, J.6    Shoelson, S.E.7
  • 32
    • 29044447292 scopus 로고    scopus 로고
    • Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver
    • [PMID: 16306362]
    • Boden G, She P, Mozzoli M, Cheung P, Gumireddy K, Reddy P, Xiang X, Luo Z, Ruderman N. Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver. Diabetes 2005; 54: 3458-3465 [PMID: 16306362 DOI: 10.2337/diabetes.54.12.3458]
    • (2005) Diabetes , vol.54 , pp. 3458-3465
    • Boden, G.1    She, P.2    Mozzoli, M.3    Cheung, P.4    Gumireddy, K.5    Reddy, P.6    Xiang, X.7    Luo, Z.8    Ruderman, N.9
  • 34
    • 40549135297 scopus 로고    scopus 로고
    • Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: Lessons from genetically engineered mice
    • [PMID: 18317565]
    • Postic C, Girard J. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J Clin Invest 2008; 118: 829-838 [PMID: 18317565 DOI: 10.1172/JCI34275]
    • (2008) J Clin Invest , vol.118 , pp. 829-838
    • Postic, C.1    Girard, J.2
  • 36
    • 34250356015 scopus 로고    scopus 로고
    • Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis
    • [PMID: 17476695]
    • Yamaguchi K, Yang L, McCall S, Huang J, Yu XX, Pandey SK, Bhanot S, Monia BP, Li YX, Diehl AM. Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. Hepatology 2007; 45: 1366-1374 [PMID: 17476695 DOI: 10.1002/hep.21655]
    • (2007) Hepatology , vol.45 , pp. 1366-1374
    • Yamaguchi, K.1    Yang, L.2    McCall, S.3    Huang, J.4    Yu, X.X.5    Pandey, S.K.6    Bhanot, S.7    Monia, B.P.8    Li, Y.X.9    Diehl, A.M.10
  • 37
    • 3142723189 scopus 로고    scopus 로고
    • Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse
    • [PMID: 15240880]
    • Ueki K, Kondo T, Tseng YH, Kahn CR. Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse. Proc Natl Acad Sci USA 2004; 101: 10422-10427 [PMID: 15240880 DOI: 10.1073/pnas.0402511101]
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10422-10427
    • Ueki, K.1    Kondo, T.2    Tseng, Y.H.3    Kahn, C.R.4
  • 38
    • 57349101675 scopus 로고    scopus 로고
    • A stress signaling pathway in adipose tissue regulates hepatic insulin resistance
    • [PMID: 19056984]
    • Sabio G, Das M, Mora A, Zhang Z, Jun JY, Ko HJ, Barrett T, Kim JK, Davis RJ. A stress signaling pathway in adipose tissue regulates hepatic insulin resistance. Science 2008; 322: 1539-1543 [PMID: 19056984 DOI: 10.1126/science.1160794]
    • (2008) Science , vol.322 , pp. 1539-1543
    • Sabio, G.1    Das, M.2    Mora, A.3    Zhang, Z.4    Jun, J.Y.5    Ko, H.J.6    Barrett, T.7    Kim, J.K.8    Davis, R.J.9
  • 39
    • 80955141082 scopus 로고    scopus 로고
    • The human plasma lipidome
    • [PMID: 22070478]
    • Quehenberger O, Dennis EA. The human plasma lipidome. N Engl J Med 2011; 365: 1812-1823 [PMID: 22070478 DOI: 10.1056/NEJMra1104901]
    • (2011) N Engl J Med , vol.365 , pp. 1812-1823
    • Quehenberger, O.1    Dennis, E.A.2
  • 40
    • 84878261341 scopus 로고    scopus 로고
    • Fatty liver: A link to cardiovascular disease-its natural history, pathogenesis, and treatment
    • [PMID: 23227282]
    • Monsour HP, Frenette CT, Wyne K. Fatty liver: a link to cardiovascular disease-its natural history, pathogenesis, and treatment. Methodist Debakey Cardiovasc J 2012; 8: 21-25 [PMID: 23227282]
    • (2012) Methodist Debakey Cardiovasc J , vol.8 , pp. 21-25
    • Monsour, H.P.1    Frenette, C.T.2    Wyne, K.3
  • 41
    • 79959672175 scopus 로고    scopus 로고
    • Adiponectin, a key adipokine in obesity related liver diseases
    • [PMID: 21734787]
    • Buechler C, Wanninger J, Neumeier M. Adiponectin, a key adipokine in obesity related liver diseases. World J Gastroenterol 2011; 17: 2801-2811 [PMID: 21734787 DOI: 10.3748/wjg. v17.i23.2801]
    • (2011) World J Gastroenterol , vol.17 , pp. 2801-2811
    • Buechler, C.1    Wanninger, J.2    Neumeier, M.3
  • 42
    • 0033586747 scopus 로고    scopus 로고
    • The role of leptin in human obesity and disease: A review of current evidence
    • [PMID: 10215564]
    • Mantzoros CS. The role of leptin in human obesity and disease: a review of current evidence. Ann Intern Med 1999; 130: 671-680 [PMID: 10215564 DOI: 10.7326/0003-4819-130-8-199904200-00014]
    • (1999) Ann Intern Med , vol.130 , pp. 671-680
    • Mantzoros, C.S.1
  • 43
    • 0036329894 scopus 로고    scopus 로고
    • Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: A manifestation of lipotoxicity?
    • [PMID: 12143049]
    • Chitturi S, Farrell G, Frost L, Kriketos A, Lin R, Fung C, Liddle C, Samarasinghe D, George J. Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: a manifestation of lipotoxicity? Hepatology 2002; 36: 403-409 [PMID: 12143049 DOI: 10.1053/jhep.2002.34738]
    • (2002) Hepatology , vol.36 , pp. 403-409
    • Chitturi, S.1    Farrell, G.2    Frost, L.3    Kriketos, A.4    Lin, R.5    Fung, C.6    Liddle, C.7    Samarasinghe, D.8    George, J.9
  • 44
    • 48049105312 scopus 로고    scopus 로고
    • Serum leptin and soluble leptin receptor in non-alcoholic fatty liver disease
    • [PMID: 18473416]
    • Huang XD, Fan Y, Zhang H, Wang P, Yuan JP, Li MJ, Zhan XY. Serum leptin and soluble leptin receptor in non-alcoholic fatty liver disease. World J Gastroenterol 2008; 14: 2888-2893 [PMID: 18473416 DOI: 10.3748/wjg.14.2888]
    • (2008) World J Gastroenterol , vol.14 , pp. 2888-2893
    • Huang, X.D.1    Fan, Y.2    Zhang, H.3    Wang, P.4    Yuan, J.P.5    Li, M.J.6    Zhan, X.Y.7
  • 46
    • 33747034520 scopus 로고    scopus 로고
    • Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory elementbinding protein-1c
    • [PMID: 16804073]
    • Biddinger SB, Miyazaki M, Boucher J, Ntambi JM, Kahn CR. Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory elementbinding protein-1c. Diabetes 2006; 55: 2032-2041 [PMID: 16804073 DOI: 10.2337/db05-0742]
    • (2006) Diabetes , vol.55 , pp. 2032-2041
    • Biddinger, S.B.1    Miyazaki, M.2    Boucher, J.3    Ntambi, J.M.4    Kahn, C.R.5
  • 47
    • 0348230958 scopus 로고    scopus 로고
    • Obesity is associated with macrophage accumulation in adipose tissue
    • [PMID: 14679176]
    • Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003; 112: 1796-1808 [PMID: 14679176 DOI: 10.1172/JCI19246]
    • (2003) J Clin Invest , vol.112 , pp. 1796-1808
    • Weisberg, S.P.1    McCann, D.2    Desai, M.3    Rosenbaum, M.4    Leibel, R.L.5    Ferrante, A.W.6
  • 48
    • 70350787404 scopus 로고    scopus 로고
    • The effects of adiponectin on interleukin-6 and MCP-1 secretion in lipopolysaccharide-treated 3T3-L1 adipocytes: Role of the NF-kappaB pathway
    • [PMID: 19885628]
    • Zoico E, Garbin U, Olioso D, Mazzali G, Fratta Pasini AM, Di Francesco V, Sepe A, Cominacini L, Zamboni M. The effects of adiponectin on interleukin-6 and MCP-1 secretion in lipopolysaccharide-treated 3T3-L1 adipocytes: role of the NF-kappaB pathway. Int J Mol Med 2009; 24: 847-851 [PMID: 19885628 DOI: 10.3892/ijmm-00000302]
    • (2009) Int J Mol Med , vol.24 , pp. 847-851
    • Zoico, E.1    Garbin, U.2    Olioso, D.3    Mazzali, G.4    Fratta Pasini, A.M.5    Di Francesco, V.6    Sepe, A.7    Cominacini, L.8    Zamboni, M.9
  • 50
    • 0037059013 scopus 로고    scopus 로고
    • Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
    • [PMID: 12456889]
    • Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang Cc Cc, Itani SI, Lodish HF, Ruderman NB. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci USA 2002; 99: 16309-16313 [PMID: 12456889 DOI: 10.1073/pnas.222657499]
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16309-16313
    • Tomas, E.1    Tsao, T.S.2    Saha, A.K.3    Murrey, H.E.4    Zhang, C.C.5    Itani, S.I.6    Lodish, H.F.7    Ruderman, N.B.8
  • 51
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • [PMID: 12840063]
    • Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003; 112: 91-100 [PMID: 12840063 DOI: 10.1172/JCI17797]
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6
  • 52
    • 30044431801 scopus 로고    scopus 로고
    • From fat to inflammation
    • [PMID: 16401483]
    • Day CP. From fat to inflammation. Gastroenterology 2006; 130: 207-210 [PMID: 16401483 DOI: 10.1053/j.gastro.2005.11.017]
    • (2006) Gastroenterology , vol.130 , pp. 207-210
    • Day, C.P.1
  • 53
    • 0031959714 scopus 로고    scopus 로고
    • Ecological control of the gastrointestinal tract. The role of probiotic flora
    • [PMID: 9505873]
    • Bengmark S. Ecological control of the gastrointestinal tract. The role of probiotic flora. Gut 1998; 42: 2-7 [PMID: 9505873 DOI: 10.1136/gut.42.1.2]
    • (1998) Gut , vol.42 , pp. 2-7
    • Bengmark, S.1
  • 54
    • 0016793479 scopus 로고
    • Endogenous ethanol production and hepatic disease following jejunoileal bypass for morbid obesity
    • [PMID: 1190105]
    • Mezey E, Imbembo AL, Potter JJ, Rent KC, Lombardo R, Holt PR. Endogenous ethanol production and hepatic disease following jejunoileal bypass for morbid obesity. Am J Clin Nutr 1975; 28: 1277-1283 [PMID: 1190105]
    • (1975) Am J Clin Nutr , vol.28 , pp. 1277-1283
    • Mezey, E.1    Imbembo, A.L.2    Potter, J.J.3    Rent, K.C.4    Lombardo, R.5    Holt, P.R.6
  • 55
    • 0023763151 scopus 로고
    • Intestinal gram-negative bacterial overgrowth in vivo augments the in vitro response of Kupffer cells to endotoxin
    • [PMID: 3052329]
    • Billiar TR, Maddaus MA, West MA, Curran RD, Wells CA, Simmons RL. Intestinal gram-negative bacterial overgrowth in vivo augments the in vitro response of Kupffer cells to endotoxin. Ann Surg 1988; 208: 532-540 [PMID: 3052329 DOI: 10.1097/00000658-198810000-00015]
    • (1988) Ann Surg , vol.208 , pp. 532-540
    • Billiar, T.R.1    Maddaus, M.A.2    West, M.A.3    Curran, R.D.4    Wells, C.A.5    Simmons, R.L.6
  • 56
    • 0037879075 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease: Lumen-liver interactions and possible role for probiotics
    • [PMID: 12713883]
    • Solga SF, Diehl AM. Non-alcoholic fatty liver disease: lumen-liver interactions and possible role for probiotics. J Hepatol 2003; 38: 681-687 [PMID: 12713883 DOI: 10.1016/S0168-8278(03)00097-7]
    • (2003) J Hepatol , vol.38 , pp. 681-687
    • Solga, S.F.1    Diehl, A.M.2
  • 60
    • 84871826394 scopus 로고    scopus 로고
    • Obesity, visceral fat, and NAFLD: Querying the Role of adipokines in the progression of nonalcoholic fatty liver disease
    • [PMID: 21991518]
    • Mirza MS. Obesity, Visceral Fat, and NAFLD: Querying the Role of Adipokines in the Progression of Nonalcoholic Fatty Liver Disease. ISRN Gastroenterol 2011; 2011: 592404 [PMID: 21991518 DOI: 10.5402/2011/592404]
    • (2011) ISRN Gastroenterol , vol.2011 , pp. 592404
    • Mirza, M.S.1
  • 61
    • 84880008350 scopus 로고    scopus 로고
    • The expanding role of fish models in understanding non-alcoholic fatty liver disease
    • [PMID: 23720231]
    • Asaoka Y, Terai S, Sakaida I, Nishina H. The expanding role of fish models in understanding non-alcoholic fatty liver disease. Dis Model Mech 2013; 6: 905-914 [PMID: 23720231 DOI: 10.1242/dmm.011981]
    • (2013) Dis Model Mech , vol.6 , pp. 905-914
    • Asaoka, Y.1    Terai, S.2    Sakaida, I.3    Nishina, H.4
  • 62
    • 33745784213 scopus 로고    scopus 로고
    • Thematic review series: Patientoriented research. Free fatty acid metabolism in human obesity
    • [PMID: 16685078]
    • Koutsari C, Jensen MD. Thematic review series: patientoriented research. Free fatty acid metabolism in human obesity. J Lipid Res 2006; 47: 1643-1650 [PMID: 16685078 DOI: 10.1194/jlr.R600011-JLR200]
    • (2006) J Lipid Res , vol.47 , pp. 1643-1650
    • Koutsari, C.1    Jensen, M.D.2
  • 63
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • [PMID: 15864352]
    • Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 2005; 115: 1343-1351 [PMID: 15864352 DOI: 10.1172/JCI23621]
    • (2005) J Clin Invest , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 64
    • 57349116780 scopus 로고    scopus 로고
    • Causes and metabolic consequences of Fatty liver
    • [PMID: 18723451]
    • Stefan N, Kantartzis K, Häring HU. Causes and metabolic consequences of Fatty liver. Endocr Rev 2008; 29: 939-960 [PMID: 18723451 DOI: 10.1210/er.2008-0009]
    • (2008) Endocr Rev , vol.29 , pp. 939-960
    • Stefan, N.1    Kantartzis, K.2    Häring, H.U.3
  • 66
    • 33747128923 scopus 로고    scopus 로고
    • Thematic review series: Patientoriented research. Recent advances in liver triacylglycerol and fatty acid metabolism using stable isotope labeling techniques
    • [PMID: 16741290]
    • Parks EJ, Hellerstein MK. Thematic review series: patientoriented research. Recent advances in liver triacylglycerol and fatty acid metabolism using stable isotope labeling techniques. J Lipid Res 2006; 47: 1651-1660 [PMID: 16741290 DOI: 10.1194/jlr.R600018-JLR200]
    • (2006) J Lipid Res , vol.47 , pp. 1651-1660
    • Parks, E.J.1    Hellerstein, M.K.2
  • 67
    • 33745897922 scopus 로고    scopus 로고
    • Translocation of long chain fatty acids across the plasma membrane-lipid rafts and fatty acid transport proteins
    • [PMID: 16477381]
    • Ehehalt R, Füllekrug J, Pohl J, Ring A, Herrmann T, Stremmel W. Translocation of long chain fatty acids across the plasma membrane-lipid rafts and fatty acid transport proteins. Mol Cell Biochem 2006; 284: 135-140 [PMID: 16477381 DOI: 10.1007/s11010-005-9034-1]
    • (2006) Mol Cell Biochem , vol.284 , pp. 135-140
    • Ehehalt, R.1    Füllekrug, J.2    Pohl, J.3    Ring, A.4    Herrmann, T.5    Stremmel, W.6
  • 68
    • 33845542745 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
    • [PMID: 17130651]
    • Morino K, Petersen KF, Shulman GI. Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction. Diabetes 2006; 55 Suppl 2: S9-S15 [PMID: 17130651 DOI: 10.2337/db06-S002]
    • (2006) Diabetes , vol.55 , pp. S9-S15
    • Morino, K.1    Petersen, K.F.2    Shulman, G.I.3
  • 69
    • 18244370762 scopus 로고    scopus 로고
    • Inflammation, stress, and diabetes
    • [PMID: 15864338]
    • Wellen KE, Hotamisligil GS. Inflammation, stress, and diabetes. J Clin Invest 2005; 115: 1111-1119 [PMID: 15864338 DOI: 10.1172/JCI25102]
    • (2005) J Clin Invest , vol.115 , pp. 1111-1119
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 70
    • 33750584214 scopus 로고    scopus 로고
    • TLR4 links innate immunity and fatty acid-induced insulin resistance
    • [PMID: 17053832]
    • Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 2006; 116: 3015-3025 [PMID: 17053832 DOI: 10.1172/JCI28898]
    • (2006) J Clin Invest , vol.116 , pp. 3015-3025
    • Shi, H.1    Kokoeva, M.V.2    Inouye, K.3    Tzameli, I.4    Yin, H.5    Flier, J.S.6
  • 71
    • 84857383028 scopus 로고    scopus 로고
    • Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass
    • [PMID: 22363740]
    • Knebel B, Haas J, Hartwig S, Jacob S, Köllmer C, Nitzgen U, Muller-Wieland D, Kotzka J. Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass. PLoS One 2012; 7: e31812 [PMID: 22363740 DOI: 10.1371/journal.pone.003181]
    • (2012) PLoS One , vol.7 , pp. e31812
    • Knebel, B.1    Haas, J.2    Hartwig, S.3    Jacob, S.4    Köllmer, C.5    Nitzgen, U.6    Muller-Wieland, D.7    Kotzka, J.8
  • 72
    • 0037216466 scopus 로고    scopus 로고
    • Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets
    • [PMID: 12499321]
    • Schwarz JM, Linfoot P, Dare D, Aghajanian K. Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets. Am J Clin Nutr 2003; 77: 43-50 [PMID: 12499321]
    • (2003) Am J Clin Nutr , vol.77 , pp. 43-50
    • Schwarz, J.M.1    Linfoot, P.2    Dare, D.3    Aghajanian, K.4
  • 73
    • 0032726283 scopus 로고    scopus 로고
    • Effects of a low-fat, high-carbohydrate diet on VLDLtriglyceride assembly, production, and clearance
    • [PMID: 10525047]
    • Parks EJ, Krauss RM, Christiansen MP, Neese RA, Hellerstein MK. Effects of a low-fat, high-carbohydrate diet on VLDLtriglyceride assembly, production, and clearance. J Clin Invest 1999; 104: 1087-1096 [PMID: 10525047 DOI: 10.1172/JCI6572]
    • (1999) J Clin Invest , vol.104 , pp. 1087-1096
    • Parks, E.J.1    Krauss, R.M.2    Christiansen, M.P.3    Neese, R.A.4    Hellerstein, M.K.5
  • 74
    • 0036217052 scopus 로고    scopus 로고
    • Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
    • [PMID: 11943743]
    • Lewis GF, Carpentier A, Adeli K, Giacca A. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev 2002; 23: 201-229 [PMID: 11943743 DOI: 10.1210/er.23.2.201]
    • (2002) Endocr Rev , vol.23 , pp. 201-229
    • Lewis, G.F.1    Carpentier, A.2    Adeli, K.3    Giacca, A.4
  • 76
    • 0036312905 scopus 로고    scopus 로고
    • Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men
    • [PMID: 12107194]
    • Seppälä-Lindroos A, Vehkavaara S, Häkkinen AM, Goto T, Westerbacka J, Sovijärvi A, Halavaara J, Yki-Järvinen H. Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. J Clin Endocrinol Metab 2002; 87: 3023-3028 [PMID: 12107194 DOI: 10.1210/jc.87.7.3023]
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3023-3028
    • Seppälä-Lindroos, A.1    Vehkavaara, S.2    Häkkinen, A.M.3    Goto, T.4    Westerbacka, J.5    Sovijärvi, A.6    Halavaara, J.7    Yki-Järvinen, H.8
  • 78
    • 0038607416 scopus 로고    scopus 로고
    • Congenital generalized lipodystrophy: Significance of triglyceride biosynthetic pathways
    • [PMID: 12826327]
    • Agarwal AK, Garg A. Congenital generalized lipodystrophy: significance of triglyceride biosynthetic pathways. Trends Endocrinol Metab 2003; 14: 214-221 [PMID: 12826327 DOI: 10.1016/S1043-2760(03)00078-X]
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 214-221
    • Agarwal, A.K.1    Garg, A.2
  • 79
    • 84872671526 scopus 로고    scopus 로고
    • Liver and diabetes. A vicious circle
    • [PMID: 23332087]
    • Loria P, Lonardo A, Anania F. Liver and diabetes. A vicious circle. Hepatol Res 2013; 43: 51-64 [PMID: 23332087 DOI: 10.1111/j.1872-034X.2012.01031.x]
    • (2013) Hepatol Res , vol.43 , pp. 51-64
    • Loria, P.1    Lonardo, A.2    Anania, F.3
  • 80
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • [PMID: 17167474]
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006; 444: 860-867 [PMID: 17167474 DOI: 10.1038/nature05485]
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 81
    • 33745861300 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • [PMID: 16823477]
    • Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest 2006; 116: 1793-1801 [PMID: 16823477 DOI: 10.1172/JCI29069]
    • (2006) J Clin Invest , vol.116 , pp. 1793-1801
    • Shoelson, S.E.1    Lee, J.2    Goldfine, A.B.3
  • 82
    • 7044231192 scopus 로고    scopus 로고
    • Biomedicine. Insulin resistance takes a trip through the ER
    • [PMID: 15486283]
    • Muoio DM, Newgard CB. Biomedicine. Insulin resistance takes a trip through the ER. Science 2004; 306: 425-426 [PMID: 15486283 DOI: 10.1126/science.1104680]
    • (2004) Science , vol.306 , pp. 425-426
    • Muoio, D.M.1    Newgard, C.B.2
  • 84
    • 18844389970 scopus 로고    scopus 로고
    • NASH: A mitochondrial disease
    • [PMID: 15885365]
    • Pessayre D, Fromenty B. NASH: a mitochondrial disease. J Hepatol 2005; 42: 928-940 [PMID: 15885365 DOI: 10.1016/j.jhep.2005.03.004]
    • (2005) J Hepatol , vol.42 , pp. 928-940
    • Pessayre, D.1    Fromenty, B.2
  • 85
    • 33646128472 scopus 로고    scopus 로고
    • 'Endocrine NAFLD' a hormonocentric perspective of nonalcoholic fatty liver disease pathogenesis
    • [PMID: 16618516]
    • Lonardo A, Carani C, Carulli N, Loria P. 'Endocrine NAFLD' a hormonocentric perspective of nonalcoholic fatty liver disease pathogenesis. J Hepatol 2006; 44: 1196-1207 [PMID: 16618516 DOI: 10.1016/j.jhep.2006.03.005]
    • (2006) J Hepatol , vol.44 , pp. 1196-1207
    • Lonardo, A.1    Carani, C.2    Carulli, N.3    Loria, P.4
  • 86
    • 84887014853 scopus 로고    scopus 로고
    • Diagnosis and management of non-alcoholic fatty liver disease and related metabolic disorders: Consensus statement from the Study Group of Liver and Metabolism, Chinese Society of Endocrinology
    • [PMID: 23560695]
    • Gao X, Fan JG. Diagnosis and management of non-alcoholic fatty liver disease and related metabolic disorders: consensus statement from the Study Group of Liver and Metabolism, Chinese Society of Endocrinology. J Diabetes 2013; 5: 406-415 [PMID: 23560695 DOI: 10.1111/1753-0407.12056]
    • (2013) J Diabetes , vol.5 , pp. 406-415
    • Gao, X.1    Fan, J.G.2
  • 87
    • 84876522373 scopus 로고    scopus 로고
    • Current concepts and management approaches in nonalcoholic fatty liver disease
    • [PMID: 23576902]
    • Attar BM, Van Thiel DH. Current concepts and management approaches in nonalcoholic fatty liver disease. Scientific World Journal 2013; 2013: 481893 [PMID: 23576902 DOI: 10.1155/2013/481893]
    • (2013) Scientific World Journal , vol.2013 , pp. 481893
    • Attar, B.M.1    Van Thiel, D.H.2
  • 92
    • 10844246291 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentrations are closely associated with nonalcoholic hepatic steatosis in obese individuals
    • [PMID: 15579183]
    • Targher G, Bertolini L, Scala L, Poli F, Zenari L, Falezza G. Decreased plasma adiponectin concentrations are closely associated with nonalcoholic hepatic steatosis in obese individuals. Clin Endocrinol (Oxf) 2004; 61: 700-703 [PMID: 15579183 DOI: 10.1111/j.1365-2265.2004.02151.x]
    • (2004) Clin Endocrinol (Oxf) , vol.61 , pp. 700-703
    • Targher, G.1    Bertolini, L.2    Scala, L.3    Poli, F.4    Zenari, L.5    Falezza, G.6
  • 93
    • 34547539428 scopus 로고    scopus 로고
    • Usefulness of a combined evaluation of the serum adiponectin level, HOMA-IR, and serum type IV collagen 7S level to predict the early stage of nonalcoholic steatohepatitis
    • [PMID: 17511754]
    • Shimada M, Kawahara H, Ozaki K, Fukura M, Yano H, Tsuchishima M, Tsutsumi M, Takase S. Usefulness of a combined evaluation of the serum adiponectin level, HOMA-IR, and serum type IV collagen 7S level to predict the early stage of nonalcoholic steatohepatitis. Am J Gastroenterol 2007; 102: 1931-1938 [PMID: 17511754 DOI: 10.1111/j.1572-0241.2007.01322.x]
    • (2007) Am J Gastroenterol , vol.102 , pp. 1931-1938
    • Shimada, M.1    Kawahara, H.2    Ozaki, K.3    Fukura, M.4    Yano, H.5    Tsuchishima, M.6    Tsutsumi, M.7    Takase, S.8
  • 96
    • 12144259379 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy to measure hepatic triglyceride content: Prevalence of hepatic steatosis in the general population
    • [PMID: 15339742]
    • Szczepaniak LS, Nurenberg P, Leonard D, Browning JD, Reingold JS, Grundy S, Hobbs HH, Dobbins RL. Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. Am J Physiol Endocrinol Metab 2005; 288: E462-E468 [PMID: 15339742 DOI: 10.1152/ajpendo.00064.2004]
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. E462-E468
    • Szczepaniak, L.S.1    Nurenberg, P.2    Leonard, D.3    Browning, J.D.4    Reingold, J.S.5    Grundy, S.6    Hobbs, H.H.7    Dobbins, R.L.8
  • 97
    • 71849092184 scopus 로고    scopus 로고
    • Validity of real time ultrasound in the diagnosis of hepatic steatosis: A prospective study
    • [PMID: 19846234]
    • Dasarathy S, Dasarathy J, Khiyami A, Joseph R, Lopez R, McCullough AJ. Validity of real time ultrasound in the diagnosis of hepatic steatosis: a prospective study. J Hepatol 2009; 51: 1061-1067 [PMID: 19846234 DOI: 10.1016/j.jhep.2009.09.00]
    • (2009) J Hepatol , vol.51 , pp. 1061-1067
    • Dasarathy, S.1    Dasarathy, J.2    Khiyami, A.3    Joseph, R.4    Lopez, R.5    McCullough, A.J.6
  • 98
    • 84875273697 scopus 로고    scopus 로고
    • Hepatic angiogenesis and fibrosis are common features in morbidly obese patients
    • [PMID: 23519653]
    • Ciupińska-Kajor M, Hartleb M, Kajor M, Kukla M, Wyleżoł M, Lange D, Liszka L. Hepatic angiogenesis and fibrosis are common features in morbidly obese patients. Hepatol Int 2013; 7: 233-240 [PMID: 23519653 DOI: 10.1007/s12072-011-9320-9]
    • (2013) Hepatol Int , vol.7 , pp. 233-240
    • Ciupińska-Kajor, M.1    Hartleb, M.2    Kajor, M.3    Kukla, M.4    Wylezoł, M.5    Lange, D.6    Liszka, L.7
  • 99
    • 84874597977 scopus 로고    scopus 로고
    • Bariatric surgery as potential treatment for nonalcoholic fatty liver disease: A future treatment by choice or by chance?
    • [PMID: 23431426]
    • Hafeez S, Ahmed MH. Bariatric surgery as potential treatment for nonalcoholic fatty liver disease: a future treatment by choice or by chance? J Obes 2013; 2013: 839275 [PMID: 23431426 DOI: 10.1155/2013/839275]
    • (2013) J Obes , vol.2013 , pp. 839275
    • Hafeez, S.1    Ahmed, M.H.2
  • 101
    • 75449094816 scopus 로고    scopus 로고
    • Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications
    • [PMID: 20041406]
    • Fabbrini E, Sullivan S, Klein S. Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications. Hepatology 2010; 51: 679-689 [PMID: 20041406 DOI: 10.1002/hep.23280]
    • (2010) Hepatology , vol.51 , pp. 679-689
    • Fabbrini, E.1    Sullivan, S.2    Klein, S.3


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