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Volumn 311, Issue 1, 2014, Pages 74-86

Long-term drug treatment for obesity: A systematic and clinical review

Author keywords

[No Author keywords available]

Indexed keywords

AMFEPRAMONE; BENZPHETAMINE; DOSPAN; LORCASERIN; METFORMIN; NALTREXONE; PHENDIMETRAZINE; PHENDIMETRAZINE TARTRATE; PHENTERMINE; PHENTERMINE PLUS TOPIRAMATE; PHENTERMINE RESIN; PLACEBO; QYSMIA; SEROTONIN RECEPTOR; SULFONYLUREA; TETRAHYDROLIPSTATIN; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; ANTIOBESITY AGENT;

EID: 84891919414     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2013.281361     Document Type: Review
Times cited : (696)

References (100)
  • 2
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention ormetformin
    • Diabetes Prevention Program Research Group
    • Knowler WC, Barrett-Connor E, Fowler SE, et al; Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention ormetformin. N Engl J Med. 2002;346(6):393-403.
    • (2002) N Engl J Med , vol.346 , Issue.6 , pp. 393-403
    • Knowler, W.C.1    Barrett-Connor, E.2    Fowler, S.E.3
  • 3
    • 84877803696 scopus 로고    scopus 로고
    • Pharmacologic treatment options for obesity: What is old is new again
    • Ryan DH, Bray GA. Pharmacologic treatment options for obesity: what is old is new again. Curr Hypertens Rep. 2013;15(3):182-189.
    • (2013) Curr Hypertens Rep , vol.15 , Issue.3 , pp. 182-189
    • Ryan, D.H.1    Bray, G.A.2
  • 4
    • 84868098172 scopus 로고    scopus 로고
    • Screening for and management of obesity in adults: US Preventive Services Task Force recommendation statement
    • US Preventive Services Task Force
    • Moyer VA; US Preventive Services Task Force. Screening for and management of obesity in adults: US Preventive Services Task Force recommendation statement. Ann Intern Med. 2012;157(5):373-378.
    • (2012) Ann Intern Med , vol.157 , Issue.5 , pp. 373-378
    • Moyer, V.A.1
  • 6
    • 79960969194 scopus 로고    scopus 로고
    • Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes
    • Look AHEAD Research Group
    • Wing RR, Lang W, Wadden TA, et al; Look AHEAD Research Group. Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes. Diabetes Care. 2011;34(7):1481-1486.
    • (2011) Diabetes Care , vol.34 , Issue.7 , pp. 1481-1486
    • Wing, R.R.1    Lang, W.2    Wadden, T.A.3
  • 7
    • 84882349072 scopus 로고    scopus 로고
    • Managing obesity in primary care practice: An overview with perspective from the POWER-UP study
    • POWER-UP Research Group Lond
    • Wadden TA, Volger S, Tsai AG, et al; POWER-UP Research Group. Managing obesity in primary care practice: an overview with perspective from the POWER-UP study. Int J Obes (Lond). 2013;37(suppl 1):S3-S11.
    • (2013) Int J Obes , vol.37 , Issue.SUPPL. 1
    • Wadden, T.A.1    Volger, S.2    Tsai, A.G.3
  • 8
    • 84860890296 scopus 로고    scopus 로고
    • The impact of extended care on the long-term maintenance of weight loss: A systematic review and meta-analysis
    • Middleton KM, Patidar SM, Perri MG. The impact of extended care on the long-term maintenance of weight loss: a systematic review and meta-analysis. Obesity Rev. 2012;13(6):509-517.
    • (2012) Obesity Rev , vol.13 , Issue.6 , pp. 509-517
    • Middleton, K.M.1    Patidar, S.M.2    Perri, M.G.3
  • 10
    • 84892528927 scopus 로고    scopus 로고
    • Prescription medications for the treatment of obesity: NIDDK weight-control information network fact sheet
    • US Dept of Health and Human Services. April Accessed September 25, 2013, 2013
    • US Dept of Health and Human Services. Prescription medications for the treatment of obesity: NIDDK weight-control information network fact sheet. NIH publication 07-4191 April 2013. http://win.niddk.nih.gov/publications/PDFs/ Prescription-Medications.pdf. Accessed September 25, 2013, 2013.
    • (2013) NIH Publication 07-4191
  • 11
    • 84892509273 scopus 로고    scopus 로고
    • Roche Laboratories, Inc. January Accessed July 2, 2013
    • Roche Laboratories, Inc. XENICAL-orlistat capsule. Revised patient package insert January 2009. http://www.accessdata.fda.gov/drugsatfda-docs/ label/2009/020766s026lbl.pdf. Accessed July 2, 2013.
    • (2009) XENICAL-orlistat Capsule. Revised Patient Package Insert
  • 14
    • 0031904104 scopus 로고    scopus 로고
    • Role of orlistat in the treatment of obese patients with type 2 diabetes: A 1-year randomized double-blind study
    • Hollander PA, Elbein SC, Hirsch IB, et al. Role of orlistat in the treatment of obese patients with type 2 diabetes: a 1-year randomized double-blind study. Diabetes Care. 1998;21(8):1288-1294.
    • (1998) Diabetes Care , vol.21 , Issue.8 , pp. 1288-1294
    • Hollander, P.A.1    Elbein, S.C.2    Hirsch, I.B.3
  • 15
    • 0032543870 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients
    • European Multicentre Orlistat Study Group
    • Sjöström L, Rissanen A, Andersen T, et al; European Multicentre Orlistat Study Group. Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. Lancet. 1998;352(9123):167-172.
    • (1998) Lancet , vol.352 , Issue.9123 , pp. 167-172
    • Sjöström, L.1    Rissanen, A.2    Andersen, T.3
  • 16
    • 0033585499 scopus 로고    scopus 로고
    • Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: A randomized controlled trial
    • Davidson MH, Hauptman J, DiGirolamo M, et al. Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomized controlled trial. JAMA. 1999;281(3):235-242.
    • (1999) JAMA , vol.281 , Issue.3 , pp. 235-242
    • Davidson, M.H.1    Hauptman, J.2    DiGirolamo, M.3
  • 17
    • 0034095342 scopus 로고    scopus 로고
    • One-year treatment of obesity: A randomized, double-blind, placebo-controlled, multicentre study of orlistat, a gastrointestinal lipase inhibitor
    • Fine N, James WP, Kopelman PG, Lean ME, Williams G. One-year treatment of obesity: a randomized, double-blind, placebo-controlled, multicentre study of orlistat, a gastrointestinal lipase inhibitor. Int J Obes Relat Metab Dis. 2000;24(3):306-313.
    • (2000) Int J Obes Relat Metab Dis , vol.24 , Issue.3 , pp. 306-313
    • Fine, N.1    James, W.P.2    Kopelman, P.G.3    Lean, M.E.4    Williams, G.5
  • 18
    • 0033829586 scopus 로고    scopus 로고
    • Orlistat in the long-term treatment of obesity in primary care settings
    • Hauptman J, Lucas C, Boldrin MN, Collins H, Segal KR. Orlistat in the long-term treatment of obesity in primary care settings. Arch Fam Med. 2000;9(2):160-167.
    • (2000) Arch Fam Med , vol.9 , Issue.2 , pp. 160-167
    • Hauptman, J.1    Lucas, C.2    Boldrin, M.N.3    Collins, H.4    Segal, K.R.5
  • 19
    • 0033823438 scopus 로고    scopus 로고
    • The effect of orlistat on body weight and coronary heart disease risk profile in obese patients: The Swedish Multimorbidity Study
    • Lindgärde F. The effect of orlistat on body weight and coronary heart disease risk profile in obese patients: the Swedish Multimorbidity Study. J Intern Med. 2000;248(3):245-254.
    • (2000) J Intern Med , vol.248 , Issue.3 , pp. 245-254
    • Lindgärde, F.1
  • 20
    • 0033629936 scopus 로고    scopus 로고
    • Weight loss, weight maintenance, and improved cardiovascular risk factors after 2 years treatment with orlistat for obesity
    • European Orlistat Obesity Study Group
    • Rössner S, Sjöström L, Noack R, Meinders AE, Noseda G; European Orlistat Obesity Study Group. Weight loss, weight maintenance, and improved cardiovascular risk factors after 2 years treatment with orlistat for obesity. Obes Res. 2000;8(1):49-61.
    • (2000) Obes Res , vol.8 , Issue.1 , pp. 49-61
    • Rössner, S.1    Sjöström, L.2    Noack, R.3    Meinders, A.E.4    Noseda, G.5
  • 21
    • 0036735197 scopus 로고    scopus 로고
    • Randomised trial of the effect of orlistat on body weight and cardiovascular disease risk profile in obese patients: UK Multimorbidity Study
    • UK Multimorbidity Study Group
    • Broom I, Wilding J, Stott P, Myers N; UK Multimorbidity Study Group. Randomised trial of the effect of orlistat on body weight and cardiovascular disease risk profile in obese patients: UK Multimorbidity Study. Int J Clin Pract. 2002;56(7):494-499.
    • (2002) Int J Clin Pract , vol.56 , Issue.7 , pp. 494-499
    • Broom, I.1    Wilding, J.2    Stott, P.3    Myers, N.4
  • 22
    • 0036845652 scopus 로고    scopus 로고
    • The effects of orlistat on body weight and glycaemic control in overweight patients with type 2 diabetes: A randomized, placebo-controlled trial
    • Hanefeld M, Sachse G. The effects of orlistat on body weight and glycaemic control in overweight patients with type 2 diabetes: a randomized, placebo-controlled trial. Diabetes Obes Metab. 2002;4(6):415-423.
    • (2002) Diabetes Obes Metab , vol.4 , Issue.6 , pp. 415-423
    • Hanefeld, M.1    Sachse, G.2
  • 23
    • 0036634125 scopus 로고    scopus 로고
    • Effect of orlistat in overweight and obese patients with type 2 diabetes treated with metformin
    • Miles JM, Leiter L, Hollander P, et al. Effect of orlistat in overweight and obese patients with type 2 diabetes treated with metformin. Diabetes Care. 2002;25(7):1123-1128.
    • (2002) Diabetes Care , vol.25 , Issue.7 , pp. 1123-1128
    • Miles, J.M.1    Leiter, L.2    Hollander, P.3
  • 25
    • 1042303480 scopus 로고    scopus 로고
    • XENical in the prevention of diabetes in obese subjects (XENDOS) study: A randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients
    • Torgerson JS, Hauptman J, Boldrin MN, Sjöström L. XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care. 2004;27(1):155-161.
    • (2004) Diabetes Care , vol.27 , Issue.1 , pp. 155-161
    • Torgerson, J.S.1    Hauptman, J.2    Boldrin, M.N.3    Sjöström, L.4
  • 26
    • 17844402287 scopus 로고    scopus 로고
    • A randomized study of orlistat in combination with a weight management programme in obese patients with type 2 diabetes treated with metformin
    • Orlistat Swedish Type 2 Diabetes Study Group
    • Berne C; Orlistat Swedish Type 2 Diabetes Study Group. A randomized study of orlistat in combination with a weight management programme in obese patients with type 2 diabetes treated with metformin. Diabet Med. 2005;22(5):612-618.
    • (2005) Diabet Med , vol.22 , Issue.5 , pp. 612-618
    • Berne, C.1
  • 27
    • 20244377226 scopus 로고    scopus 로고
    • Effect of orlistat on cardiovascular disease risk in obese adults
    • Swinburn BA, Carey D, Hills AP, et al. Effect of orlistat on cardiovascular disease risk in obese adults. Diabetes Obes Metab. 2005;7(3):254-262.
    • (2005) Diabetes Obes Metab , vol.7 , Issue.3 , pp. 254-262
    • Swinburn, B.A.1    Carey, D.2    Hills, A.P.3
  • 28
    • 84857999164 scopus 로고    scopus 로고
    • Effects of 1-year orlistat treatment compared to placebo on insulin resistance parameters in patients with type 2 diabetes
    • Derosa G, Cicero AF, D'Angelo A, Fogari E, Maffioli P. Effects of 1-year orlistat treatment compared to placebo on insulin resistance parameters in patients with type 2 diabetes. J Clin Pharm Ther. 2012;37(2):187-195.
    • (2012) J Clin Pharm Ther , vol.37 , Issue.2 , pp. 187-195
    • Derosa, G.1    Cicero, A.F.2    D'Angelo, A.3    Fogari, E.4    Maffioli, P.5
  • 29
    • 77954635020 scopus 로고    scopus 로고
    • Multicenter, placebo-controlled trial of lorcaserin for weight management
    • Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM) Study Group
    • Smith SR,Weissman NJ, Anderson CM, et al; Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM) Study Group. Multicenter, placebo-controlled trial of lorcaserin for weight management. N Engl J Med. 2010;363(3):245-256.
    • (2010) N Engl J Med , vol.363 , Issue.3 , pp. 245-256
    • Smith, S.R.1    Weissman, N.J.2    Anderson, C.M.3
  • 30
    • 80053539943 scopus 로고    scopus 로고
    • A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: The BLOSSOM trial
    • BLOSSOM Clinical Trial Group
    • Fidler MC, Sanchez M, Raether B, et al; BLOSSOM Clinical Trial Group. A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trial. J Clin Endocrinol Metab. 2011;96(10):3067-3077.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.10 , pp. 3067-3077
    • Fidler, M.C.1    Sanchez, M.2    Raether, B.3
  • 31
    • 84862869642 scopus 로고    scopus 로고
    • Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: The BLOOM-DM study
    • Silver Spring
    • O'Neil PM, Smith SR, Weissman NJ, et al. Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study. Obesity (Silver Spring). 2012;20(7):1426-1436.
    • (2012) Obesity , vol.20 , Issue.7 , pp. 1426-1436
    • O'Neil, P.M.1    Smith, S.R.2    Weissman, N.J.3
  • 32
    • 84856246606 scopus 로고    scopus 로고
    • Controlled-release phentermine/topiramate in severely obese adults: A randomized controlled trial (EQUIP)
    • Silver Spring
    • Allison DB, Gadde KM, Garvey WT, et al. Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP). Obesity (Silver Spring). 2012;20(2): 330-342.
    • (2012) Obesity , vol.20 , Issue.2 , pp. 330-342
    • Allison, D.B.1    Gadde, K.M.2    Garvey, W.T.3
  • 33
    • 79954561234 scopus 로고    scopus 로고
    • Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): A randomised, placebo-controlled, phase 3 trial
    • Gadde KM, Allison DB, Ryan DH, et al. Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial. Lancet. 2011;377(9774):1341-1352.
    • (2011) Lancet , vol.377 , Issue.9774 , pp. 1341-1352
    • Gadde, K.M.1    Allison, D.B.2    Ryan, D.H.3
  • 34
    • 0346250180 scopus 로고    scopus 로고
    • Long-term pharmacotherapy for overweight and obesity: A systematic review and meta-analysis of randomized controlled trials
    • Padwal R, Li SK, Lau DC. Long-term pharmacotherapy for overweight and obesity: a systematic review and meta-analysis of randomized controlled trials. Int J Obes Rel Metab Dis. 2003;27(12):1437-1446.
    • (2003) Int J Obes Rel Metab Dis , vol.27 , Issue.12 , pp. 1437-1446
    • Padwal, R.1    Li, S.K.2    Lau, D.C.3
  • 35
    • 15944367788 scopus 로고    scopus 로고
    • Meta-analysis: Pharmacologic treatment of obesity
    • Li Z, Maglione M, Tu W, et al. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med. 2005;142(7):532-546.
    • (2005) Ann Intern Med , vol.142 , Issue.7 , pp. 532-546
    • Li, Z.1    Maglione, M.2    Tu, W.3
  • 36
    • 37249083878 scopus 로고    scopus 로고
    • Long term pharmacotherapy for obesity and overweight: Updated meta-analysis
    • Rucker D, Padwal R, Li SK, Curioni C, Lau DC. Long term pharmacotherapy for obesity and overweight: updated meta-analysis. BMJ. 2007;335(7631):1194- 1199.
    • (2007) BMJ , vol.335 , Issue.7631 , pp. 1194-1199
    • Rucker, D.1    Padwal, R.2    Li, S.K.3    Curioni, C.4    Lau, D.C.5
  • 37
    • 34648836960 scopus 로고    scopus 로고
    • Weight-loss outcomes: A systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up
    • Franz MJ, VanWormer JJ, Crain AL, et al. Weight-loss outcomes: a systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up. J Am Diet Assoc. 2007;107(10):1755-1767.
    • (2007) J Am Diet Assoc , vol.107 , Issue.10 , pp. 1755-1767
    • Franz, M.J.1    VanWormer, J.J.2    Crain, A.L.3
  • 38
    • 16544369107 scopus 로고    scopus 로고
    • Changes in body weight and serum lipid profile in obese patients treated with orlistat in addition to a hypocaloric diet: A systematic review of randomized clinical trials
    • Hutton B, Fergusson D. Changes in body weight and serum lipid profile in obese patients treated with orlistat in addition to a hypocaloric diet: a systematic review of randomized clinical trials. Am J Clin Nutr. 2004;80(6):1461-1468.
    • (2004) Am J Clin Nutr , vol.80 , Issue.6 , pp. 1461-1468
    • Hutton, B.1    Fergusson, D.2
  • 39
    • 84876483004 scopus 로고    scopus 로고
    • Efficacy and safety of lorcaserin in obese adults: Ameta-analysis of 1-year randomized controlled trials (RCTs) and narrative review on short-term RCTs
    • Chan EW, He Y, Chui CS, Wong AY, Lau WC, Wong IC. Efficacy and safety of lorcaserin in obese adults: ameta-analysis of 1-year randomized controlled trials (RCTs) and narrative review on short-term RCTs. Obes Rev. 2013;14(5):383-392.
    • (2013) Obes Rev , vol.14 , Issue.5 , pp. 383-392
    • Chan, E.W.1    He, Y.2    Chui, C.S.3    Wong, A.Y.4    Lau, W.C.5    Wong, I.C.6
  • 40
    • 84892495966 scopus 로고    scopus 로고
    • submitted October 17, 2011. Vivus Inc Accessed September 23, 2013
    • US Food and Drug Administration. Vivus, data on file: new drug application 022580: integrated summary of effectiveness, submitted October 17, 2011. Vivus Inc; 2011. http://www.accessdata.fda.gov/drugsatfda-docs/nda/2012/ 022580Orig1s000OtherR.pdf. Accessed September 23, 2013.
    • (2011) Vivus, Data on File: New Drug Application 022580: Integrated Summary of Effectiveness
  • 41
    • 84892553375 scopus 로고    scopus 로고
    • New Drug Application 22580: VI-0521 QNEXA (phentermine/topiramate)
    • Sponsor: VIVUS. February 22, Table 7. Accessed September 21, 2013
    • Roberts MD. New Drug Application 22580: VI-0521 QNEXA (phentermine/topiramate). Sponsor: VIVUS. February 22, 2012. Table 7. US Food and Drug Administration Endocrinologic and Metabolic Drugs Advisory Committee Meeting Clinical Briefing Document. Page 32. http://www.fda.gov/downloads/ AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/ EndocrinologicandMetabolicDrugsAdvisory Committee/UCM292315.pdf. Accessed September 21, 2013.
    • (2012) US Food and Drug Administration Endocrinologic and Metabolic Drugs Advisory Committee Meeting Clinical Briefing Document , pp. 32
    • Roberts, M.D.1
  • 42
    • 85047695511 scopus 로고    scopus 로고
    • Pharmacotherapy for obesity: A quantitative analysis of four decades of published randomized clinical trials
    • Haddock CK, Poston WS, Dill PL, Foreyt JP, Ericsson M. Pharmacotherapy for obesity: a quantitative analysis of four decades of published randomized clinical trials. Int J Obes Relat Metab Disord. 2002;26(2):262-273.
    • (2002) Int J Obes Relat Metab Disord , vol.26 , Issue.2 , pp. 262-273
    • Haddock, C.K.1    Poston, W.S.2    Dill, P.L.3    Foreyt, J.P.4    Ericsson, M.5
  • 43
    • 84860330219 scopus 로고    scopus 로고
    • Food and Drug Administration's Obesity Drug Guidance Document: A short history
    • Colman E. Food and Drug Administration's Obesity Drug Guidance Document: a short history. Circulation. 2012;125(17):2156-2164.
    • (2012) Circulation , vol.125 , Issue.17 , pp. 2156-2164
    • Colman, E.1
  • 45
    • 81855194456 scopus 로고    scopus 로고
    • Blood pressure and heart rate effects, weight loss and maintenance during long-term phentermine pharmacotherapy for obesity
    • Silver Spring
    • Hendricks EJ, Greenway FL,Westman EC, Gupta AK. Blood pressure and heart rate effects, weight loss and maintenance during long-term phentermine pharmacotherapy for obesity. Obesity (Silver Spring). 2011;19(12):2351-2360.
    • (2011) Obesity , vol.19 , Issue.12 , pp. 2351-2360
    • Hendricks, E.J.1    Greenway, F.L.2    Westman, E.C.3    Gupta, A.K.4
  • 46
    • 84899006199 scopus 로고    scopus 로고
    • Use of prescription antiobesity drugs in the United States
    • published online ahead of print September 9, 2013 doi:10.1002/phar.1342
    • Hampp C, Kang EM, Borders-Hemphill V. Use of prescription antiobesity drugs in the United States [published online ahead of print September 9, 2013]. Pharmacotherapy. 2013. doi:10.1002/phar.1342.
    • (2013) Pharmacotherapy
    • Hampp, C.1    Kang, E.M.2    Borders-Hemphill, V.3
  • 47
    • 0001661402 scopus 로고
    • Comparison of continuous and intermittent anorectic therapy in obesity
    • Munro JF, MacCuish AC, Wilson EM, Duncan LJ. Comparison of continuous and intermittent anorectic therapy in obesity. Br Med J. 1968;1(5588):352-354.
    • (1968) Br Med J , vol.1 , Issue.5588 , pp. 352-354
    • Munro, J.F.1    MacCuish, A.C.2    Wilson, E.M.3    Duncan, L.J.4
  • 48
    • 73649187354 scopus 로고
    • Observations on the use of phendimetrazine, a new anorexigenic agent, in obese diabetics
    • Runyan JW Jr. Observations on the use of phendimetrazine, a new anorexigenic agent, in obese diabetics. Curr Ther Res Clin Exp. 1962;4:270-275.
    • (1962) Curr Ther Res Clin Exp , vol.4 , pp. 270-275
    • Runyan Jr., J.W.1
  • 49
    • 0014265028 scopus 로고
    • Sustained-action phendimetrazine in obesity
    • Hadler AJ. Sustained-action phendimetrazine in obesity. J Clin Pharmacol J New Drugs. 1968;8(2):113-117.
    • (1968) J Clin Pharmacol J New Drugs , vol.8 , Issue.2 , pp. 113-117
    • Hadler, A.J.1
  • 50
    • 2942519185 scopus 로고    scopus 로고
    • Cholesterol lowering effect of dietary weight loss and orlistat treatment-efficacy and limitations
    • Erdmann J, Lippl F, Klose G, Schusdziarra V. Cholesterol lowering effect of dietary weight loss and orlistat treatment-efficacy and limitations. Aliment Pharmacol Ther. 2004;19(11):1173-1179.
    • (2004) Aliment Pharmacol Ther , vol.19 , Issue.11 , pp. 1173-1179
    • Erdmann, J.1    Lippl, F.2    Klose, G.3    Schusdziarra, V.4
  • 51
    • 77958584741 scopus 로고    scopus 로고
    • Long-term changes in blood pressure following orlistat and sibutramine treatment: A meta-analysis
    • Johansson K, Sundstrom J, Neovius K, Rossner S, Neovius M. Long-term changes in blood pressure following orlistat and sibutramine treatment: a meta-analysis. Obes Rev. 2010;11(11):777-791.
    • (2010) Obes Rev , vol.11 , Issue.11 , pp. 777-791
    • Johansson, K.1    Sundstrom, J.2    Neovius, K.3    Rossner, S.4    Neovius, M.5
  • 52
    • 84862674296 scopus 로고    scopus 로고
    • Effect of anti-obesity drug on cardiovascular risk factors: A systematic review and meta-analysis of randomized controlled trials
    • Zhou YH, Ma XQ, Wu C, et al. Effect of anti-obesity drug on cardiovascular risk factors: a systematic review and meta-analysis of randomized controlled trials. PLoS One. 2012;7(6):e39062.
    • (2012) PLoS One , vol.7 , Issue.6
    • Zhou, Y.H.1    Ma, X.Q.2    Wu, C.3
  • 53
    • 0034969219 scopus 로고    scopus 로고
    • Gastrointestinal side effects of orlistatmay be prevented by concomitant prescription of natural fibers (psyllium mucilloid)
    • Cavaliere H, Floriano I, Medeiros-Neto G. Gastrointestinal side effects of orlistatmay be prevented by concomitant prescription of natural fibers (psyllium mucilloid). Int J Obes Relat Metab Disord. 2001;25(7):1095-1099.
    • (2001) Int J Obes Relat Metab Disord , vol.25 , Issue.7 , pp. 1095-1099
    • Cavaliere, H.1    Floriano, I.2    Medeiros-Neto, G.3
  • 54
    • 34748899434 scopus 로고    scopus 로고
    • Long-term persistence with orlistat and sibutramine in a population-based cohort
    • Lond
    • Padwal R, Kezouh A, Levine M, Etminan M. Long-term persistence with orlistat and sibutramine in a population-based cohort. Int J Obes (Lond). 2007;31(10):1567-1570.
    • (2007) Int J Obes , vol.31 , Issue.10 , pp. 1567-1570
    • Padwal, R.1    Kezouh, A.2    Levine, M.3    Etminan, M.4
  • 55
    • 0030876952 scopus 로고    scopus 로고
    • Valvular heart disease associated with fenfluramine-phentermine
    • Connolly HM, Crary JL, McGoon MD, et al. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med. 1997;337(9):581-588.
    • (1997) N Engl J Med , vol.337 , Issue.9 , pp. 581-588
    • Connolly, H.M.1    Crary, J.L.2    McGoon, M.D.3
  • 57
    • 84875854090 scopus 로고    scopus 로고
    • Changes in cardiovascular risk associated with phentermine and topiramate extended-release in participants with comorbidities and a body mass index ≥27 kg/m(2)
    • Davidson MH, Tonstad S, Oparil S, Schwiers M, Day WW, Bowden CH. Changes in cardiovascular risk associated with phentermine and topiramate extended-release in participants with comorbidities and a body mass index ≥27 kg/m(2). Am J Cardiol. 2013;111(8):1131-1138.
    • (2013) Am J Cardiol , vol.111 , Issue.8 , pp. 1131-1138
    • Davidson, M.H.1    Tonstad, S.2    Oparil, S.3    Schwiers, M.4    Day, W.W.5    Bowden, C.H.6
  • 58
    • 84856388467 scopus 로고    scopus 로고
    • Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): A randomized, placebo-controlled, phase 3 extension study
    • Garvey WT, Ryan DH, Look M, et al. Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study. Am J Clin Nutr. 2012;95(2):297-308.
    • (2012) Am J Clin Nutr , vol.95 , Issue.2 , pp. 297-308
    • Garvey, W.T.1    Ryan, D.H.2    Look, M.3
  • 59
    • 84868101572 scopus 로고    scopus 로고
    • Use of topiramate in pregnancy and risk of oral clefts
    • Margulis AV,Mitchell AA, Gilboa SM, et al Use of topiramate in pregnancy and risk of oral clefts. Am J Obstet Gynecol. 2012;207(5):405e1-405e7.
    • (2012) Am J Obstet Gynecol , vol.207 , Issue.5
    • Margulis, A.V.1    Mitchell, A.A.2    Gilboa, S.M.3
  • 63
    • 84858407374 scopus 로고    scopus 로고
    • Report No.: 11-05159-EF-1. US Preventive Services Task Force Evidence Syntheses, formerly Systematic Evidence Reviews. Rockville, MD: Agency for Healthcare Research and Quality
    • LeBlanc E, O'Connor E, Whitlock EP, Patnode C, Kapka T. Screening for and Management of Obesity and Overweight in Adults. Report No.: 11-05159-EF-1. US Preventive Services Task Force Evidence Syntheses, formerly Systematic Evidence Reviews. Rockville, MD: Agency for Healthcare Research and Quality; 2011.
    • (2011) Screening for and Management of Obesity and Overweight in Adults
    • LeBlanc, E.1    O'Connor, E.2    Whitlock, E.P.3    Patnode, C.4    Kapka, T.5
  • 64
    • 84859372038 scopus 로고    scopus 로고
    • Long-term safety, tolerability, and weight loss associated with metformin in the Diabetes Prevention Program Outcomes Study
    • Diabetes Prevention Program Research Group
    • Diabetes Prevention Program Research Group. Long-term safety, tolerability, and weight loss associated with metformin in the Diabetes Prevention Program Outcomes Study. Diabetes Care. 2012;35(4):731-737.
    • (2012) Diabetes Care , vol.35 , Issue.4 , pp. 731-737
  • 65
    • 77952421438 scopus 로고    scopus 로고
    • Effectiveness of medications used to attenuate antipsychotic-related weight gain and metabolic abnormalities: A systematic review and meta-analysis
    • Maayan L, Vakhrusheva J, Correll CU. Effectiveness of medications used to attenuate antipsychotic-related weight gain and metabolic abnormalities: a systematic review and meta-analysis. Neuropsychopharmacology. 2010;35(7):1520-1530.
    • (2010) Neuropsychopharmacology , vol.35 , Issue.7 , pp. 1520-1530
    • Maayan, L.1    Vakhrusheva, J.2    Correll, C.U.3
  • 67
    • 78650636365 scopus 로고    scopus 로고
    • The effect of pramlintide acetate on glycemic control and weight in patients with type 2 diabetes mellitus and in obese patients without diabetes: A systematic review and meta-analysis
    • Singh-Franco D, Perez A, Harrington C. The effect of pramlintide acetate on glycemic control and weight in patients with type 2 diabetes mellitus and in obese patients without diabetes: a systematic review and meta-analysis. Diabetes Obes Metab. 2011;13(2):169-180.
    • (2011) Diabetes Obes Metab , vol.13 , Issue.2 , pp. 169-180
    • Singh-Franco, D.1    Perez, A.2    Harrington, C.3
  • 68
    • 77956094570 scopus 로고    scopus 로고
    • Enhanced weight loss following coadministration of pramlintide with sibutramine or phentermine in a multicenter trial
    • Silver Spring
    • Aronne LJ, Halseth AE, Burns CM, Miller S, Shen LZ. Enhanced weight loss following coadministration of pramlintide with sibutramine or phentermine in a multicenter trial. Obesity (Silver Spring). 2010;18(9):1739-1746.
    • (2010) Obesity , vol.18 , Issue.9 , pp. 1739-1746
    • Aronne, L.J.1    Halseth, A.E.2    Burns, C.M.3    Miller, S.4    Shen, L.Z.5
  • 69
    • 84892517153 scopus 로고    scopus 로고
    • Summary Minutes of the Endocrinologic and Metabolic Drugs Advisory Committee Accessed July 3, 2013
    • Tran PT, Thomas A; Summary Minutes of the Endocrinologic and Metabolic Drugs Advisory Committee. US Food and Drug Administration Center for Drug Evaluation and Research: December 7, 2010. http://www.fda.gov/downloads/ AdvisoryCommittees /CommitteesMeetingMaterials/Drugs/ EndocrinologicandMetabolicDrugsAdvisory Committee/UCM241508.pdf. Accessed July 3, 2013.
    • US Food and Drug Administration Center for Drug Evaluation and Research: December 7, 2010
    • Tran, P.T.1    Thomas, A.2
  • 71
    • 77956057548 scopus 로고    scopus 로고
    • Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): A multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
    • COR-I Study Group
    • Greenway FL, Fujioka K, Plodkowski RA, et al; COR-I Study Group. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2010;376(9741):595-605.
    • (2010) Lancet , vol.376 , Issue.9741 , pp. 595-605
    • Greenway, F.L.1    Fujioka, K.2    Plodkowski, R.A.3
  • 72
    • 84879324574 scopus 로고    scopus 로고
    • A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II)
    • COR-II Study Group Silver Spring
    • Apovian CM, Aronne L, Rubino D, et al; COR-II Study Group. A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II). Obesity (Silver Spring). 2013;21(5):935-943.
    • (2013) Obesity , vol.21 , Issue.5 , pp. 935-943
    • Apovian, C.M.1    Aronne, L.2    Rubino, D.3
  • 73
    • 77956904326 scopus 로고    scopus 로고
    • Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: The COR-BMOD trial
    • Silver Spring
    • Wadden TA, Foreyt JP, Foster GD, et al. Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial. Obesity (Silver Spring). 2011;19(1):110-120.
    • (2011) Obesity , vol.19 , Issue.1 , pp. 110-120
    • Wadden, T.A.1    Foreyt, J.P.2    Foster, G.D.3
  • 74
    • 84862299162 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide-1 receptor agonists on body weight: Ameta-analysis
    • published online May 20, 2012 doi: 10.1155/2012/672658
    • Monami M, Dicembrini I, Marchionni N, Rotella CM, Mannucci E. Effects of glucagon-like peptide-1 receptor agonists on body weight: ameta-analysis [published online May 20, 2012]. Exp Diabetes Res. 2012. doi: 10.1155/2012/672658
    • (2012) Exp Diabetes Res
    • Monami, M.1    Dicembrini, I.2    Marchionni, N.3    Rotella, C.M.4    Mannucci, E.5
  • 75
    • 84862207266 scopus 로고    scopus 로고
    • Safety, tolerability, and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide
    • NN8022-1807 Investigators. [published online August 16, 2011]. Lond doi:10.1038/ijo.2011.158
    • Astrup A, Carraro R, Finer N, et al; NN8022-1807 Investigators. Safety, tolerability, and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide [published online August 16, 2011]. Int J Obes (Lond). 2012. doi:10.1038/ijo.2011.158
    • (2012) Int J Obes
    • Astrup, A.1    Carraro, R.2    Finer, N.3
  • 76
    • 77956090389 scopus 로고    scopus 로고
    • Effects of exenatide and lifestyle modification on body weight and glucose tolerance in obese subjects with and without pre-diabetes
    • Rosenstock J, Klaff LJ, Schwartz S, et al. Effects of exenatide and lifestyle modification on body weight and glucose tolerance in obese subjects with and without pre-diabetes. Diabetes Care. 2010;33(6):1173-1175.
    • (2010) Diabetes Care , vol.33 , Issue.6 , pp. 1173-1175
    • Rosenstock, J.1    Klaff, L.J.2    Schwartz, S.3
  • 79
    • 84887840117 scopus 로고    scopus 로고
    • Weight maintenance and additional weight loss with liraglutide after low-calorie diet-induced weight loss: The SCALE Maintenance randomized study
    • published online September 3, 2013 doi: 10.1038/ijo.2013.148
    • Wadden T, Hollander P, Klein S, et al. Weight maintenance and additional weight loss with liraglutide after low-calorie diet-induced weight loss: the SCALE Maintenance randomized study [published online September 3, 2013]. Int J Obes. 2013. doi: 10.1038/ijo.2013.148
    • (2013) Int J Obes
    • Wadden, T.1    Hollander, P.2    Klein, S.3
  • 80
  • 81
    • 32644435689 scopus 로고    scopus 로고
    • Obesity research-limitations of methods, measurements, and medications
    • Simons-Morton DG, Obarzanek E, Cutler JA. Obesity research-limitations of methods, measurements, and medications. JAMA. 2006;295(7):826-828.
    • (2006) JAMA , vol.295 , Issue.7 , pp. 826-828
    • Simons-Morton, D.G.1    Obarzanek, E.2    Cutler, J.A.3
  • 82
    • 84863937753 scopus 로고    scopus 로고
    • Lemons for obesity
    • Lauer MS. Lemons for obesity. Ann Intern Med. 2012;157(2):139-140.
    • (2012) Ann Intern Med , vol.157 , Issue.2 , pp. 139-140
    • Lauer, M.S.1
  • 83
    • 7944233492 scopus 로고    scopus 로고
    • Prescription weight loss pill use among Americans: Patterns of pill use and lessons learned from the fen-phen market withdrawal
    • Blanck HM, Khan LK, Serdula MK. Prescription weight loss pill use among Americans: patterns of pill use and lessons learned from the fen-phen market withdrawal. Prev Med. 2004;39(6):1243-1248.
    • (2004) Prev Med , vol.39 , Issue.6 , pp. 1243-1248
    • Blanck, H.M.1    Khan, L.K.2    Serdula, M.K.3
  • 84
    • 84892490445 scopus 로고    scopus 로고
    • Obesity drug outcome measures: Results of a multi-stakeholder critical dialoque
    • doi:10.1007/s13679-013-0052-0
    • Kahan S, Ferguson C, David S, Divine L. Obesity drug outcome measures: results of a multi-stakeholder critical dialoque. Current Obesity Reports. 2013;2(2):128-133. doi:10.1007/s13679-013-0052-0
    • (2013) Current Obesity Reports , vol.2 , Issue.2 , pp. 128-133
    • Kahan, S.1    Ferguson, C.2    David, S.3    Divine, L.4
  • 85
    • 0037261362 scopus 로고    scopus 로고
    • Predictive value of early weight loss in obesity management with orlistat: An evidence-based assessment of prescribing guidelines
    • Rissanen A, Lean M, Rössner S, Segal KR, Sjöström L. Predictive value of early weight loss in obesity management with orlistat: an evidence-based assessment of prescribing guidelines. Int J Obes RelatMetab Disord. 2003;27(1):103-109.
    • (2003) Int J Obes RelatMetab Disord , vol.27 , Issue.1 , pp. 103-109
    • Rissanen, A.1    Lean, M.2    Rössner, S.3    Segal, K.R.4    Sjöström, L.5
  • 86
    • 33646002321 scopus 로고    scopus 로고
    • Prediction of response to sibutramine therapy in obese non-diabetic and diabetic patients
    • Finer N, Ryan DH, Renz CL, Hewkin AC. Prediction of response to sibutramine therapy in obese non-diabetic and diabetic patients. Diabetes Obes Metab. 2006;8(2):206-213.
    • (2006) Diabetes Obes Metab , vol.8 , Issue.2 , pp. 206-213
    • Finer, N.1    Ryan, D.H.2    Renz, C.L.3    Hewkin, A.C.4
  • 87
    • 84892537173 scopus 로고    scopus 로고
    • US Food and Drug Administration Endocrinologic and Metabolic Drugs Advisory Committee clinical briefing document May 10, Arena Pharmaceuticals, Inc. Accessed October 5, 2013
    • Golden J. US Food and Drug Administration Endocrinologic and Metabolic Drugs Advisory Committee clinical briefing document May 10, 2012. Arena Pharmaceuticals, Inc. New Drug Application 022529: Lorcaserin hydrochloride tablets 10mg. http://www.fda.gov/downloads/AdvisoryCommittees/ CommitteesMeetingMaterials/Drugs/EndocrinologicandMetabolicDrugsAdvisory Committee/UCM303198.pdf. Accessed October 5, 2013.
    • (2012) New Drug Application 022529: Lorcaserin Hydrochloride Tablets 10mg
    • Golden, J.1
  • 89
    • 84880323061 scopus 로고    scopus 로고
    • Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes
    • Look AHEAD Research Group
    • Wing RR, Bolin P, Brancati FL, et al; Look AHEAD Research Group. Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med. 2013;369(2):145-154.
    • (2013) N Engl J Med , vol.369 , Issue.2 , pp. 145-154
    • Wing, R.R.1    Bolin, P.2    Brancati, F.L.3
  • 91
    • 27844487932 scopus 로고    scopus 로고
    • Randomized trial of lifestyle modification and pharmacotherapy for obesity
    • Wadden TA, Berkowitz RI, Womble LG, et al. Randomized trial of lifestyle modification and pharmacotherapy for obesity. N Engl J Med. 2005;353(20):2111- 2120.
    • (2005) N Engl J Med , vol.353 , Issue.20 , pp. 2111-2120
    • Wadden, T.A.1    Berkowitz, R.I.2    Womble, L.G.3
  • 92
    • 84882276623 scopus 로고    scopus 로고
    • AACE comprehensive diabetes management algorithm 2013
    • Garber AJ, Abrahamson MJ, Barzilay JI, et al AACE comprehensive diabetes management algorithm 2013. Endocr Pract. 2013;19(2):327-336.
    • (2013) Endocr Pract , vol.19 , Issue.2 , pp. 327-336
    • Garber, A.J.1    Abrahamson, M.J.2    Barzilay, J.I.3
  • 93
    • 63049083098 scopus 로고    scopus 로고
    • One-year weight losses in the Look AHEAD study: Factors associated with success
    • Look AHEAD Research Group Silver Spring
    • Wadden TA,West DS, Neiberg RH, et al; Look AHEAD Research Group. One-year weight losses in the Look AHEAD study: factors associated with success. Obesity (Silver Spring). 2009;17(4): 713-722.
    • (2009) Obesity , vol.17 , Issue.4 , pp. 713-722
    • Wadden, T.A.1    West, D.S.2    Neiberg, R.H.3
  • 94
    • 0026593857 scopus 로고
    • Long-term weight control study. II (weeks 34 to 104). An open-label study of continuous fenfluramine plus phentermine versus targeted intermittent medication as adjuncts to behavior modification, caloric restriction, and exercise
    • Weintraub M, Sundaresan PR, Schuster B, et al. Long-term weight control study. II (weeks 34 to 104). an open-label study of continuous fenfluramine plus phentermine versus targeted intermittent medication as adjuncts to behavior modification, caloric restriction, and exercise. Clin Pharmacol Ther. 1992;51(5):595-601.
    • (1992) Clin Pharmacol Ther , vol.51 , Issue.5 , pp. 595-601
    • Weintraub, M.1    Sundaresan, P.R.2    Schuster, B.3
  • 95
    • 0016162028 scopus 로고
    • Intermittent treatment with anorectic drugs
    • Silverstone T. Intermittent treatment with anorectic drugs. Practitioner. 1974;213(1274): 245-252.
    • (1974) Practitioner , vol.213 , Issue.1274 , pp. 245-252
    • Silverstone, T.1
  • 96
    • 0033020351 scopus 로고    scopus 로고
    • Orlistat, a lipase inhibitor, for weight maintenance after conventional dieting: A 1-y study
    • Hill JO, Hauptman J, Anderson JW, et al. Orlistat, a lipase inhibitor, for weight maintenance after conventional dieting: a 1-y study. Am J Clin Nutr. 1999;69(6):1108-1116.
    • (1999) Am J Clin Nutr , vol.69 , Issue.6 , pp. 1108-1116
    • Hill, J.O.1    Hauptman, J.2    Anderson, J.W.3
  • 97
    • 84883657397 scopus 로고    scopus 로고
    • New tools for weight loss therapy enable a more robust medical model for obesity treatment: Rationale for a complications-centric approach
    • Garvey WT. New tools for weight loss therapy enable a more robust medical model for obesity treatment: rationale for a complications-centric approach. Endocr Pract. 2013;19(5):864-874.
    • (2013) Endocr Pract , vol.19 , Issue.5 , pp. 864-874
    • Garvey, W.T.1
  • 98
    • 78149305142 scopus 로고    scopus 로고
    • Antidepressants and body weight: A comprehensive review and meta-analysis
    • Serretti A, Mandelli L. Antidepressants and body weight: a comprehensive review and meta-analysis. J Clin Psychiatry. 2010;71(10):1259-1272.
    • (2010) J Clin Psychiatry , vol.71 , Issue.10 , pp. 1259-1272
    • Serretti, A.1    Mandelli, L.2
  • 99
    • 67649631173 scopus 로고    scopus 로고
    • Combination pharmaceutical therapies for obesity
    • Gadde KM, Allison DB. Combination pharmaceutical therapies for obesity. Expert Opin Pharmacother. 2009;10(6):921-925.
    • (2009) Expert Opin Pharmacother , vol.10 , Issue.6 , pp. 921-925
    • Gadde, K.M.1    Allison, D.B.2
  • 100
    • 69749110806 scopus 로고    scopus 로고
    • How physician obesity specialists use drugs to treat obesity
    • Silver Spring
    • Hendricks EJ, Rothman RB, Greenway FL. How physician obesity specialists use drugs to treat obesity. Obesity (Silver Spring). 2009;17(9):1730-1735.
    • (2009) Obesity , vol.17 , Issue.9 , pp. 1730-1735
    • Hendricks, E.J.1    Rothman, R.B.2    Greenway, F.L.3


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