-
1
-
-
41349090064
-
Anti-obesity drugs and neural circuits of feeding
-
Adan, R. A. H., Vanderschuren, L. J. M. J. and la Fleur, S. E. (2008). Anti-obesity drugs and neural circuits of feeding. Trends Pharmacol. Sci. 29, 208-217.
-
(2008)
Trends Pharmacol. Sci.
, vol.29
, pp. 208-217
-
-
Adan, R.A.H.1
Vanderschuren, L.J.M.J.2
La Fleur, S.E.3
-
2
-
-
77956094570
-
Enhanced weight loss following coadministration of pramlintide with sibutramine or phentermine in a multicenter trial
-
Aronne, L. J., Halseth, A. E., Burns, C. M., Miller, S. and Shen, L. Z. (2010). Enhanced weight loss following coadministration of pramlintide with sibutramine or phentermine in a multicenter trial. Obesity 18, 1739-1746.
-
(2010)
Obesity
, vol.18
, pp. 1739-1746
-
-
Aronne, L.J.1
Halseth, A.E.2
Burns, C.M.3
Miller, S.4
Shen, L.Z.5
-
3
-
-
70350619609
-
Effects of liraglutide in the treatment of obesity: A randomised, double-blind, placebo-controlled study
-
Astrup, A., Rossner, S., Van Gaal, L., Rissanen, A., Niskanen, L., Madsen, J., Rasmussen, M. F. and Lean, M. E. J. (2009). Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study. Lancet 374, 1606-1616.
-
(2009)
Lancet
, vol.374
, pp. 1606-1616
-
-
Astrup, A.1
Rossner, S.2
Van Gaal, L.3
Rissanen, A.4
Niskanen, L.5
Madsen, J.6
Rasmussen, M.F.7
Lean, M.E.J.8
-
4
-
-
84862220741
-
Safety, tolerability and sustained weight loss over 2 years with once daily human GLP-1 analog, liraglutide
-
Astrup, A., Carraro, R., Finer, N., Harper, A., Kunesova, M, Lean, M. E. J., Niskanen, L., Rasmussen, M. F., Rissanen, A., Rossner, S. et al. (2011). Safety, tolerability and sustained weight loss over 2 years with once daily human GLP-1 analog, liraglutide. Int. J. Obesity 36, 890.
-
(2011)
Int. J. Obesity
, vol.36
, pp. 890
-
-
Astrup, A.1
Carraro, R.2
Finer, N.3
Harper, A.4
Kunesova, M.5
Lean, M.E.J.6
Niskanen, L.7
Rasmussen, M.F.8
Rissanen, A.9
Rossner, S.10
-
5
-
-
77952541313
-
The endocannabinoid system, eating behavior and energy homeostasis: The end or a new beginning?
-
Bermudez-Silva, F. J., Viveros, M. P., McPartland, J. M. and Rodriguez de Fonseca, F. (2010). The endocannabinoid system, eating behavior and energy homeostasis: the end or a new beginning? Pharmacol. Biochem. Behav. 95, 375-382.
-
(2010)
Pharmacol. Biochem. Behav.
, vol.95
, pp. 375-382
-
-
Bermudez-Silva, F.J.1
Viveros, M.P.2
McPartland, J.M.3
Rodriguez De Fonseca, F.4
-
6
-
-
0023791240
-
Mode of action of tetrahydrolipstatin: A derivative of the naturally occurring lipase inhibitor lipstatin
-
Borgstrom, B. (1988). Mode of action of tetrahydrolipstatin: a derivative of the naturally occurring lipase inhibitor lipstatin. Biochim. Biophys. Acta 962, 308-316.
-
(1988)
Biochim. Biophys. Acta
, vol.962
, pp. 308-316
-
-
Borgstrom, B.1
-
7
-
-
34249821944
-
Pharmacological treatment of the overweight patient
-
DOI 10.1124/pr.59.2.2
-
Bray, G. A. and Greenway, F. L. (2007). Pharmacological treatment of the overweight patient. Pharmacol. Rev. 59, 151-184. (Pubitemid 46855438)
-
(2007)
Pharmacological Reviews
, vol.59
, Issue.2
, pp. 151-184
-
-
Bray, G.A.1
Greenway, F.L.2
-
8
-
-
0036735197
-
Randomised trial of the effect of orlistat on body weight and cardiovascular disease risk profile in obese patients: UK multimorbidity study
-
Broom, I., Wilding, J., Scott, P. and Myers, N. (2002). Randomised trial of the effect of orlistat on body weight and cardiovascular disease risk profile in obese patients: UK multimorbidity study. Int. J. Clin. Pract. 56, 494-499.
-
(2002)
Int. J. Clin. Pract.
, vol.56
, pp. 494-499
-
-
Broom, I.1
Wilding, J.2
Scott, P.3
Myers, N.4
-
9
-
-
77953239310
-
Novel selective antagonist of the cannabinoid CB1 receptor, MJ15, with prominent anti-obesity effect in rodent models
-
Chen, W., Tang, H., Liu, H., Long, L., Gong, Z, Zheng, J., Chi, M., Xie, Y., Zheng, Z., Li, S. et al. (2010). Novel selective antagonist of the cannabinoid CB1 receptor, MJ15, with prominent anti-obesity effect in rodent models. Eur. J. Pharmacol. 637, 178-185.
-
(2010)
Eur. J. Pharmacol.
, vol.637
, pp. 178-185
-
-
Chen, W.1
Tang, H.2
Liu, H.3
Long, L.4
Gong, Z.5
Zheng, J.6
Chi, M.7
Xie, Y.8
Zheng, Z.9
Li, S.10
-
10
-
-
78549281113
-
The neutral cannabinoid CB1 receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat
-
Cluny, N. L., Chambers, A. P., Vemuri, V. K., Wood, J. T., Eller, L. K., Freni, C., Reimer, R. A., Makriyannis, A. and Sharkey, K. A. (2011). The neutral cannabinoid CB1 receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat. Pharmacol. Biochem. Behav. 97, 537-543.
-
(2011)
Pharmacol. Biochem. Behav.
, vol.97
, pp. 537-543
-
-
Cluny, N.L.1
Chambers, A.P.2
Vemuri, V.K.3
Wood, J.T.4
Eller, L.K.5
Freni, C.6
Reimer, R.A.7
Makriyannis, A.8
Sharkey, K.A.9
-
11
-
-
24644477445
-
Anorectics on trial: A half-century of federal regulation of prescription appetite suppressants
-
Colman, E. (2005). Anorectics on trial: a half-century of federal regulation of prescription appetite suppressants. Ann. Int. Med. 143, 380-385.
-
(2005)
Ann. Int. Med.
, vol.143
, pp. 380-385
-
-
Colman, E.1
-
12
-
-
0030876952
-
Valvular heart disease associated with fenfluramine phentermine
-
DOI 10.1056/NEJM199708283370901
-
Connolly, H. M., Crary, J. L., McGoon, M. D., Hensrud, D. D., Edwards, B. S., Edwards, W. D. and Schaff, H. V. (1997). Valvular heart disease associated with fenfluramine-phentermine. N. Eng. J. Med. 337, 581-588. (Pubitemid 27360757)
-
(1997)
New England Journal of Medicine
, vol.337
, Issue.9
, pp. 581-588
-
-
Connolly, H.M.1
Crary, J.L.2
McGoon, M.D.3
Hensrud, D.D.4
Edwards, B.S.5
Edwards, W.D.6
Schaff, H.V.7
-
13
-
-
33750510903
-
The obesity pipeline: Current strategies in the development of anti-obesity drugs
-
DOI 10.1038/nrd2136, PII NRD2136
-
Cooke, D. and Bloom, S. (2006). The obesity pipeline: current strategies in the development of anti-obesity drugs. Nat. Rev. Drug Discov. 5, 919-931. (Pubitemid 44660605)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.11
, pp. 919-931
-
-
Cooke, D.1
Bloom, S.2
-
14
-
-
31744452243
-
Obesity: America's epidemic
-
Daniels, J. (2006a). Obesity: America's epidemic. Am. J. Nurs. 106, 40-49.
-
(2006)
Am. J. Nurs.
, vol.106
, pp. 40-49
-
-
Daniels, J.1
-
15
-
-
33645296563
-
The consequences of childhood overweight and obesity
-
Daniels, S. R. (2006b). The consequences of childhood overweight and obesity. Future Child 16, 47-67.
-
(2006)
Future Child
, vol.16
, pp. 47-67
-
-
Daniels, S.R.1
-
16
-
-
11244331742
-
Comparison of the Atkins, Ornish, Weight Watchers, and Zone Diets for weight loss and heart disease risk reduction: A randomized trial
-
DOI 10.1001/jama.293.1.43
-
Dansinger, M. L., Gleason, J. A., Griffith, J. L., Selker, H. P. and Schaefer, E. J. (2005). Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease reduction: a randomised trial. JAMA 293, 43-53. (Pubitemid 40066698)
-
(2005)
Journal of the American Medical Association
, vol.293
, Issue.1
, pp. 43-53
-
-
Dansinger, M.L.1
Gleason, J.A.2
Griffith, J.L.3
Selker, H.P.4
Schaefer, E.J.5
-
17
-
-
70349308687
-
A new glucagon and GLP-1 co-agonist eliminates obesity in rodents
-
Day, J. W., Ottaway, N., Patterson, J. T., Gelfanov, V., Smiley, D., Gidda, J, Findeisen, H., Bruemmer, D., Drucker, D. J., Chaudhary, N. et al. (2009). A new glucagon and GLP-1 co-agonist eliminates obesity in rodents. Nat. Chem. Biol. 5, 749-757.
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 749-757
-
-
Day, J.W.1
Ottaway, N.2
Patterson, J.T.3
Gelfanov, V.4
Smiley, D.5
Gidda, J.6
Findeisen, H.7
Bruemmer, D.8
Drucker, D.J.9
Chaudhary, N.10
-
18
-
-
27844463517
-
Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
-
DOI 10.1056/NEJMoa044537
-
Despres, J. P., Golay, A. and Sjostrom, L. (2005). Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N. Eng. J. Med. 353, 2121-2134. (Pubitemid 41653104)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.20
, pp. 2121-2134
-
-
Despres, J.-P.1
Golay, A.2
Sjostrom, L.3
-
19
-
-
70849085551
-
Obesity treatment: Novel peripheral targets
-
Field, B. C. T., Chaudhri, O. B. and Bloom, S. R. (2009). Obesity treatment: novel peripheral targets. Br. J. Clin. Pharmacol. 68, 830-843.
-
(2009)
Br. J. Clin. Pharmacol.
, vol.68
, pp. 830-843
-
-
Field, B.C.T.1
Chaudhri, O.B.2
Bloom, S.R.3
-
20
-
-
35848935201
-
Cause-specific excess deaths associated with underweight, overweight, and obesity
-
DOI 10.1001/jama.298.17.2028
-
Flegal, K. M., Graubard, B. I., Williamson, D. F. and Gail, M. H. (2007). Cause-specific excess deaths associated with underweight, overweight, and obesity. JAMA 298, 2028-2037. (Pubitemid 350074800)
-
(2007)
Journal of the American Medical Association
, vol.298
, Issue.17
, pp. 2028-2037
-
-
Flegal, K.M.1
Graubard, B.I.2
Williamson, D.F.3
Gail, M.H.4
-
21
-
-
0037425578
-
Years of life lost due to obesity
-
DOI 10.1001/jama.289.2.187
-
Fontaine, K. R., Redden, D. T., Wang, C., Westfall, A. J. and Allison, D. B. (2003). Years of life lost due to obesity. JAMA 298, 187-193. (Pubitemid 36068706)
-
(2003)
Journal of the American Medical Association
, vol.289
, Issue.2
, pp. 187-193
-
-
Fontaine, K.R.1
Redden, D.T.2
Wang, C.3
Westfall, A.O.4
Allison, D.B.5
-
22
-
-
0034861648
-
Relationship of childhood obesity to coronary heart disease risk factors in adulthood: The Bogalusa heart study
-
DOI 10.1542/peds.108.3.712
-
Freedman, D. S., Khan, L. K., Dietz, W. H., Srinivasan, S. R. and Berenson, G. S. (2001). Relationship of childhood obesity to coronary heart disease risk factors in adulthood: the Bogalusa Heart Study. Pediatrics 108, 712-718. (Pubitemid 32786603)
-
(2001)
Pediatrics
, vol.108
, Issue.3
, pp. 712-718
-
-
Freedman, D.S.1
Khan, L.K.2
Dietz, W.H.3
Srinivasan, S.R.4
Berenson, G.S.5
-
23
-
-
57949112266
-
Rational design of a combination medication for the treatment of obesity
-
DOI 10.1038/oby.2008.461, PII OBY2008461
-
Greenway, F. L., Whitehouse, M. J., Guttadauria, M., Anderson, J. W., Atkinson, R. L., Fujioka, K., Gadde, K. M., Gupta, A. K., O'Neil, P., Schumacher, D. et al. (2009). Rational design of a combination medication for the treatment of obesity. Obesity 17, 30-39. (Pubitemid 50324544)
-
(2009)
Obesity
, vol.17
, Issue.1
, pp. 30-39
-
-
Greenway, F.L.1
Whitehouse, M.J.2
Guttadauria, M.3
Anderson, J.W.4
Atkinson, R.L.5
Fujioka, K.6
Gadde, K.M.7
Gupta, A.K.8
O'Neil, P.9
Schumacher, D.10
Smith, D.11
Dunayevich, E.12
Tollefson, G.D.13
Weber, E.14
Cowley, M.A.15
-
24
-
-
77951665710
-
Pharmacological management of appetite expression in obesity
-
Halford, J. C. G., Boyland, E. J., Blundell, J. E., Kirkham, T. C. and Harrold, J. A. (2010). Pharmacological management of appetite expression in obesity. Nat. Rev. Endocrinol. 6, 255-269.
-
(2010)
Nat. Rev. Endocrinol.
, vol.6
, pp. 255-269
-
-
Halford, J.C.G.1
Boyland, E.J.2
Blundell, J.E.3
Kirkham, T.C.4
Harrold, J.A.5
-
25
-
-
67749104112
-
Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists
-
Hanssen, K. B., Knop, F. K., Holst, J. J. and Vilsboll, T. (2009). Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists. Int. J. Clin. Pract. 63, 1154-1160.
-
(2009)
Int. J. Clin. Pract.
, vol.63
, pp. 1154-1160
-
-
Hanssen, K.B.1
Knop, F.K.2
Holst, J.J.3
Vilsboll, T.4
-
26
-
-
25844457693
-
Obesity
-
DOI 10.1016/S0140-6736(05)67483-1, PII S0140673605674831
-
Haslam, D. W. and James, W. P. T. (2005). Obesity. Lancet 366, 1197-1209. (Pubitemid 41393598)
-
(2005)
Lancet
, vol.366
, Issue.9492
, pp. 1197-1209
-
-
Haslam, D.W.1
James, W.P.T.2
-
27
-
-
70849120492
-
Regulatory challenges for new drugs to treat obesity and comorbid metabolic disorders
-
Heal, D. J., Gosden, J. and Smith, S. L. (2009). Regulatory challenges for new drugs to treat obesity and comorbid metabolic disorders. Br. J. Clin. Pharmacol. 68, 861-874.
-
(2009)
Br. J. Clin. Pharmacol.
, vol.68
, pp. 861-874
-
-
Heal, D.J.1
Gosden, J.2
Smith, S.L.3
-
28
-
-
77956284607
-
Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects
-
James, W. P. T., Caterson, I. D., Couthino, W., Finer, N., Van Gaal, L. F., Maggioni, A. P., Torp-Pederson, C., Sharma, A. M., Shepherd, G. M., Rode, R. A. et al. (2010). Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N. Eng. J. Med. 363, 905-917.
-
(2010)
N. Eng. J. Med.
, vol.363
, pp. 905-917
-
-
James, W.P.T.1
Caterson, I.D.2
Couthino, W.3
Finer, N.4
Van Gaal, L.F.5
Maggioni, A.P.6
Torp-Pederson, C.7
Sharma, A.M.8
Shepherd, G.M.9
Rode, R.A.10
-
29
-
-
77957754436
-
New approaches to the pharmacological treatment of obesity: Can they break through the efficacy barrier?
-
Kennett, G. A. and Clifton, P. G. (2010). New approaches to the pharmacological treatment of obesity: Can they break through the efficacy barrier? Pharmacol. Biochem. Behav. 97, 63-83.
-
(2010)
Pharmacol. Biochem. Behav.
, vol.97
, pp. 63-83
-
-
Kennett, G.A.1
Clifton, P.G.2
-
30
-
-
67651065803
-
Cannabinoids and appetite: Food craving and food pleasure
-
Kirkham, T. C. (2009). Cannabinoids and appetite: food craving and food pleasure. Int. Rev. Psychiat. 21, 163-171.
-
(2009)
Int. Rev. Psychiat.
, vol.21
, pp. 163-171
-
-
Kirkham, T.C.1
-
31
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman, P. G. (2000). Obesity as a medical problem. Nature 404, 635-643.
-
(2000)
Nature
, vol.404
, pp. 635-643
-
-
Kopelman, P.G.1
-
33
-
-
0023638829
-
Glucagon-like peptide-1 7-36: A physiological incretin in man
-
Kreymann, B., Williams, G., Ghatei, M. A. and Bloom S. R. (1987). Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet 2, 1300-1304. (Pubitemid 17156636)
-
(1987)
Lancet
, vol.2
, Issue.8571
, pp. 1300-1304
-
-
Kreymann, B.1
Williams, G.2
Ghatei, M.A.3
Bloom, S.R.4
-
34
-
-
58149138840
-
Should peripheral CB1 cannabinoid receptors be selectively targeted for therapeutic gain?
-
Kunos, G., Osei-Hyiaman, D., Batkai, S., Sharkey, K. A. and Makriyannis, A. (2008). Should peripheral CB1 cannabinoid receptors be selectively targeted for therapeutic gain? Trends Pharmacol. Sci. 30, 1-7.
-
(2008)
Trends Pharmacol. Sci.
, vol.30
, pp. 1-7
-
-
Kunos, G.1
Osei-Hyiaman, D.2
Batkai, S.3
Sharkey, K.A.4
Makriyannis, A.5
-
35
-
-
79955746716
-
Personalized medicine can pave the way for the safe use of CB1 receptor antagonists
-
Lazary, J., Juhasz, G, Hunyady, L. and Bagdy, G. (2011). Personalized medicine can pave the way for the safe use of CB1 receptor antagonists. Trends Pharmacol. Sci. 32, 270-280.
-
(2011)
Trends Pharmacol. Sci.
, vol.32
, pp. 270-280
-
-
Lazary, J.1
Juhasz, G.2
Hunyady, L.3
Bagdy, G.4
-
36
-
-
80053516605
-
Effectiveness of primary care -relevant treatments for obesity in adults: A systematic evidence review for the U. S. Preventive Services Task Force
-
LeBlanc, E. S., O'Connor, E., Wtitlock, P. D., Patnode, C. D. and Kapka, T. (2011). Effectiveness of primary care -relevant treatments for obesity in adults: a systematic evidence review for the U. S. Preventive Services Task Force. Ann. Int. Med. 155, 434-447.
-
(2011)
Ann. Int. Med.
, vol.155
, pp. 434-447
-
-
LeBlanc, E.S.1
O'Connor, E.2
Wtitlock, P.D.3
Patnode, C.D.4
Kapka, T.5
-
37
-
-
15944367788
-
Meta-analysis: Pharmacologic treatment of obesity
-
Li, Z., Maglione, M., Tu, W., Mojica, D., Arterburn, D., Shugaman, L. R., Hilton, L., Suttorp, M., Solomon, V., Shekelle, P. G. et al. (2005). Meta-analysis: pharmacologic treatment of obesity. Ann. Intern. Med. 142, 532-546.
-
(2005)
Ann. Intern. Med.
, vol.142
, pp. 532-546
-
-
Li, Z.1
Maglione, M.2
Tu, W.3
Mojica, D.4
Arterburn, D.5
Shugaman, L.R.6
Hilton, L.7
Suttorp, M.8
Solomon, V.9
Shekelle, P.G.10
-
38
-
-
80053159809
-
CNS opioid signaling separates cannabinoid receptor 1-mediated effects on body weight and mood-related behavior in mice
-
Lockie, S. H., Czyzyk, T. A., Chaudhary, N., Perez-Tilve, D., Woods, S. C., Oldfield, B. J., Statnick, M. A. and Tschöp, M. H. (2011). CNS opioid signaling separates cannabinoid receptor 1-mediated effects on body weight and mood-related behavior in mice. Endocrinol. 152, 3661-3667.
-
(2011)
Endocrinol.
, vol.152
, pp. 3661-3667
-
-
Lockie, S.H.1
Czyzyk, T.A.2
Chaudhary, N.3
Perez-Tilve, D.4
Woods, S.C.5
Oldfield, B.J.6
Statnick, M.A.7
Tschöp, M.H.8
-
39
-
-
0037066583
-
The discovery and status of sibutramine as an anti-obesity drug
-
DOI 10.1016/S0014-2999(02)01423-1, PII S0014299902014231
-
Luque, C. A. and Rey, J. A. (2002). The discovery and status of sibutramine as an antiobesity drug. Eur. J. Pharmacol. 440, 119-128. (Pubitemid 34458019)
-
(2002)
European Journal of Pharmacology
, vol.440
, Issue.2-3
, pp. 119-128
-
-
Luque, C.A.1
Rey, J.A.2
-
40
-
-
0032434821
-
Sibutramine. A review of its contribution to the management of obesity
-
DOI 10.2165/00003495-199856060-00019
-
McNeely, W. and Goa, K. L. (1998). Sibutramine. A review of its contribution to the management of obesity. Drugs 56, 1093-1124. (Pubitemid 29010230)
-
(1998)
Drugs
, vol.56
, Issue.6
, pp. 1093-1124
-
-
McNeely, W.1
Goa, K.L.2
-
42
-
-
33745225219
-
Anti-obesity therapies
-
DOI 10.1038/nrd2037, PII N2037
-
Melnikova, I. and Wages, D. (2006). Anti-obesity therapies. Nat. Rev. Drug Discov. 5, 369-370. (Pubitemid 43904927)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.5
, pp. 369-370
-
-
Melnikova, I.1
Wages, D.2
-
44
-
-
78951494193
-
Additive effects of cannabinoid CB1 receptors blockade and cholecystokinin on feeding inhibition
-
Orio, L., Crespo, I., Lopez-Moreno, J. A., Reyes-Cabello, C., Rodriguez de Fonseca, F. and Gomez de Heras, R. (2011). Additive effects of cannabinoid CB1 receptors blockade and cholecystokinin on feeding inhibition. Pharmacol. Biochem. Behav. 98, 220-226.
-
(2011)
Pharmacol. Biochem. Behav.
, vol.98
, pp. 220-226
-
-
Orio, L.1
Crespo, I.2
Lopez-Moreno, J.A.3
Reyes-Cabello, C.4
Rodriguez De Fonseca, F.5
Gomez De Heras, R.6
-
45
-
-
70349757017
-
Contrave, a bupropion and naltrexone combination therapy for the potential treatment of obesity
-
Padwal, R. (2009). Contrave, a bupropion and naltrexone combination therapy for the potential treatment of obesity. Curr. Opin. Invest. Drugs 10, 1117-1125.
-
(2009)
Curr. Opin. Invest. Drugs
, vol.10
, pp. 1117-1125
-
-
Padwal, R.1
-
46
-
-
33645502759
-
The pharmacology of cannabinoid receptors and their ligands: An overview
-
Pertwee, R. G. (2006). The pharmacology of cannabinoid receptors and their ligands: an overview. Int. J. Obesity 30, S13-S18.
-
(2006)
Int. J. Obesity
, vol.30
-
-
Pertwee, R.G.1
-
47
-
-
32644441249
-
Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients - RIO-North America: A randomized controlled trial
-
DOI 10.1001/jama.295.7.761
-
Pi-Sunyer, F., Aronne, L. J., Heshmati, H. M., Devin, J. and Rosenstock, J. (2006). Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk in overweight or obese patients - RIO-North America: a randomised controlled trial. JAMA 295, 761-775. (Pubitemid 43244304)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.7
, pp. 761-775
-
-
Pi-Sunyer, F.X.1
Aronne, L.J.2
Heshmati, H.M.3
Devin, J.4
Rosenstock, J.5
-
48
-
-
84865507204
-
Obesity: What next after the CB1 antagonists' failure
-
Plieth, J. (2008). Obesity: what next after the CB1 antagonists' failure. Scrip 2008, 44-47.
-
(2008)
Scrip
, vol.2008
, pp. 44-47
-
-
Plieth, J.1
-
49
-
-
77957749920
-
The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behavior
-
Randall, P. A., Vemuri, V. K., Segovia, K. N., Torres, E. F., Hosmer, S., Nunes, E. J., Santerre, J. L., Makriyannis, A. and Salamone, J. D. (2010). The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behavior. Pharmacol. Biochem. Behav. 97, 179-184.
-
(2010)
Pharmacol. Biochem. Behav.
, vol.97
, pp. 179-184
-
-
Randall, P.A.1
Vemuri, V.K.2
Segovia, K.N.3
Torres, E.F.4
Hosmer, S.5
Nunes, E.J.6
Santerre, J.L.7
Makriyannis, A.8
Salamone, J.D.9
-
50
-
-
69749086148
-
Enhanced weight loss with pramlintide/metreleptin: An integrated neurohumoral approach to obesity pharmacotherapy
-
Ravussin, E., Smith, S. R., Mitchell, J. A., Shringarpure, R., Shan, K., Maier, H., Koda, J. E. and Weyer, C. (2009). Enhanced weight loss with pramlintide/metreleptin: an integrated neurohumoral approach to obesity pharmacotherapy. Obesity 17, 1736-1743.
-
(2009)
Obesity
, vol.17
, pp. 1736-1743
-
-
Ravussin, E.1
Smith, S.R.2
Mitchell, J.A.3
Shringarpure, R.4
Shan, K.5
Maier, H.6
Koda, J.E.7
Weyer, C.8
-
51
-
-
77957754120
-
Behavioural satiety sequence (BSS): Separating wheat from chaff in the behavioural pharmacology of appetite
-
Rodgers, R. J., Holch, P. and Tallett, A. J. (2010). Behavioural satiety sequence (BSS): Separating wheat from chaff in the behavioural pharmacology of appetite. Pharmacol. Biochem. Behav. 97, 3-14.
-
(2010)
Pharmacol. Biochem. Behav.
, vol.97
, pp. 3-14
-
-
Rodgers, R.J.1
Holch, P.2
Tallett, A.J.3
-
52
-
-
49449114438
-
Antiobesity effects of the beta-cell hormone amylin in combination with phenteramine or sibutramine in diety-induced obese rats
-
Roth, J. D., Trevaskis, J. L., Wilson, J., Lei, C., Athanacio, J., Mack, C., Kesty, N. C., Coffey, T., Weyer, C. and Parkes, D. G. (2008). Antiobesity effects of the beta-cell hormone amylin in combination with phenteramine or sibutramine in diety-induced obese rats. Int. J. Obesity 32, 1201-1210.
-
(2008)
Int. J. Obesity
, vol.32
, pp. 1201-1210
-
-
Roth, J.D.1
Trevaskis, J.L.2
Wilson, J.3
Lei, C.4
Athanacio, J.5
Mack, C.6
Kesty, N.C.7
Coffey, T.8
Weyer, C.9
Parkes, D.G.10
-
53
-
-
77956176469
-
'Weighing in' on synergy: Preclinical research on neurohumoral anti-obesity combinations
-
Roth, J. D., Trevaskis, J. L., Turek, V. F. and Parkes, D. G. (2010). 'Weighing in' on synergy: preclinical research on neurohumoral anti-obesity combinations. Brain Res. 1350, 86-94.
-
(2010)
Brain Res.
, vol.1350
, pp. 86-94
-
-
Roth, J.D.1
Trevaskis, J.L.2
Turek, V.F.3
Parkes, D.G.4
-
54
-
-
0001534655
-
Metabolic effects of glucagon in the Wistar rat
-
Salter, J. M. (1960). Metabolic effects of glucagon in the Wistar rat. Am. J. Clin. Nutr. 8, 535-539.
-
(1960)
Am. J. Clin. Nutr.
, vol.8
, pp. 535-539
-
-
Salter, J.M.1
-
55
-
-
70849104324
-
New central targets for the treatment of obesity
-
Sargent, B. J. and Moore, N. A. (2009). New central targets for the treatment of obesity. Br. J. Clin. Pharmacol. 68, 852-860.
-
(2009)
Br. J. Clin. Pharmacol.
, vol.68
, pp. 852-860
-
-
Sargent, B.J.1
Moore, N.A.2
-
56
-
-
33751001942
-
Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: A randomised controlled study
-
DOI 10.1016/S0140-6736(06)69571-8, PII S0140673606695718
-
Scheen, A. J., Finer, N., Hollander, P., Jensen, M. D. and Van Gaal, L. F. (2006). Efficacy and tolerability of rimonabant in oiverweight or obese patients with Type 2 diabetes: a randomised controlled study. Lancet 368, 1660-1672. (Pubitemid 46048528)
-
(2006)
Lancet
, vol.368
, Issue.9548
, pp. 1660-1672
-
-
Scheen, A.J.1
Finer, N.2
Hollander, P.3
Jensen, M.D.4
Van Gaal, L.F.5
-
57
-
-
34548090763
-
Effects of bariatric surgery on mortality in Swedish obese subjects
-
Sjostrom, L., Narbro, K., Sjostrom, C. D., Karason, K., Larsson, B., Wedel, H., Lystig, T., Sullivan, M., Bouchard, C., Carlsson, B. et al. (2007). Swedish Obese Subjects Study. Effects of bariatric surgery on mortality in Swedish obese subjects. N. Eng. J. Med. 357, 741-752. (Pubitemid 47295641)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.8
, pp. 741-752
-
-
Sjostrom, L.1
Narbro, K.2
Sjostrom, C.D.3
Karason, K.4
Larsson, B.5
Wedel, H.6
Lystig, T.7
Sullivan, M.8
Bouchard, C.9
Carlsson, B.10
Bengtsson, C.11
Dahlgren, S.12
Gummesson, A.13
Jacobson, P.14
Karlsson, J.15
Lindroos, A.-K.16
Lonroth, H.17
Naslund, I.18
Olbers, T.19
Stenlof, K.20
Torgerson, J.21
Agren, G.22
Carlsson, L.M.S.23
more..
-
58
-
-
43549107263
-
Endogenous opioids and cannabinoids: System interactions in the regulation of appetite, grooming and scratching
-
DOI 10.1016/j.physbeh.2008.02.009, PII S0031938408000668
-
Tallett, A. J., Blundell, J. E. and Rodgers, R. J. (2008). Endogenous opioids and cannabinoids: system interactions in the regulation of appetite, grooming and scratching. Physiol. Behav. 94, 422-431. (Pubitemid 351680293)
-
(2008)
Physiology and Behavior
, vol.94
, Issue.3
, pp. 422-431
-
-
Tallett, A.J.1
Blundell, J.E.2
Rodgers, R.J.3
-
59
-
-
1042303480
-
XENical in the Prevention of Diabetes in Obese Subjects (XENDOS) Study: A randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients
-
DOI 10.2337/diacare.27.1.155
-
Torgerson, J. S., Hauptman, J., Boldrin, M. N. and Sjostrom, L. (2004). Xenical in the prevention of diabetes in obese subjects (XENDOS) study: a randomised study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care 27, 155-161. (Pubitemid 38196725)
-
(2004)
Diabetes Care
, vol.27
, Issue.1
, pp. 155-161
-
-
Torgerson, J.S.1
Hauptman, J.2
Boldrin, M.N.3
Sjostrom, L.4
-
60
-
-
54349121294
-
Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: Magnitude and mechanisms
-
Trevaskis, J. L., Coffey, T., Cole, R., Lei, C., Wittmer, C., Walsh, B., Weyer, C., Koda, J., Baron, A. D., Parkes, D. G. et al. (2008). Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: magnitude and mechanisms. Endocrinology 149, 5679-5687.
-
(2008)
Endocrinology
, vol.149
, pp. 5679-5687
-
-
Trevaskis, J.L.1
Coffey, T.2
Cole, R.3
Lei, C.4
Wittmer, C.5
Walsh, B.6
Weyer, C.7
Koda, J.8
Baron, A.D.9
Parkes, D.G.10
-
61
-
-
13344282056
-
A role for glucagon-like peptide-1 in the central regulation of feeding
-
Turton, M. D., O'Shea, D., Gunn, I., Edwards, C. M. B., Meeran, K., Heath, M., Lambert, P. D., Wilding, J. P. H., Smith, D. M., Ghatei, M. A. et al. (2006). A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 379, 69-72.
-
(2006)
Nature
, vol.379
, pp. 69-72
-
-
Turton, M.D.1
O'Shea, D.2
Gunn, I.3
Edwards, C.M.B.4
Meeran, K.5
Heath, M.6
Lambert, P.D.7
Wilding, J.P.H.8
Smith, D.M.9
Ghatei, M.A.10
-
62
-
-
17144382751
-
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-Year experience from the RIO-Europe study
-
DOI 10.1016/S0140-6736(05)66374-X
-
Van Gaal, L. F., Rissanen, A. M., Scheen, A. J., Ziegler, O. and Rossner, S. (2005). Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from RIO-Europe study. Lancet 365, 1389-1397. (Pubitemid 40523733)
-
(2005)
Lancet
, vol.365
, Issue.9468
, pp. 1389-1397
-
-
Van Gaal, L.F.1
Rissanen, A.M.2
Scheen, A.J.3
Ziegler, O.4
Rossner, S.5
-
63
-
-
40949112752
-
Pharmacotherapeutic targeting of the endocannabinoid signaling system: Drugs for obesity and the metabolic syndrome
-
DOI 10.1016/j.physbeh.2007.11.012, PII S0031938407004453
-
Vemuri, V. K., Janero, D. R. and Makriyannis, A. (2008). Therapeutic targeting of the endocannabinoid signaling system: drugs for obesity and the metabolic syndrome. Physiol. Behav. 93, 671-686. (Pubitemid 351410420)
-
(2008)
Physiology and Behavior
, vol.93
, Issue.4-5
, pp. 671-686
-
-
Vemuri, V.K.1
Janero, D.R.2
Makriyannis, A.3
-
64
-
-
43549093795
-
Preclinical developments in antiobesity drugs
-
(ed. T. C. Kirkham and S. J. Cooper), . London: Academic Press
-
Vickers, S. P. and Cheetham, S. C. (2007). Preclinical developments in antiobesity drugs. In Appetite and Body Weight (ed. T. C. Kirkham and S. J. Cooper), pp. 323-336. London: Academic Press.
-
(2007)
Appetite and Body Weight
, pp. 323-336
-
-
Vickers, S.P.1
Cheetham, S.C.2
-
65
-
-
80052943665
-
The utility of animal models to evaluate novel anti-obesity agents
-
Vickers, S. P., Jackson, H. C. and Cheetham, S. C. (2011). The utility of animal models to evaluate novel anti-obesity agents. Br. J. Pharmacol. 164, 1248-1262.
-
(2011)
Br. J. Pharmacol.
, vol.164
, pp. 1248-1262
-
-
Vickers, S.P.1
Jackson, H.C.2
Cheetham, S.C.3
-
66
-
-
42449164739
-
2c receptor agonist alone and in combination on motivation for palatable food: A dose-addition analysis study in mice
-
DOI 10.1124/jpet.107.131771
-
Ward, S. J., Lefever, T. W., Jackson, C., Tallarida, R. J. and Walker, E. A. (2008). Effects of a cannabinoid1 receptor antagonist and serotonin2C receptor agonist alone and in combination on motivation for palatable food: a dose addition analysis study in mice. J. Pharmacol. Exp. Ther. 325, 567-576. (Pubitemid 351574781)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.325
, Issue.2
, pp. 567-576
-
-
Ward, S.J.1
Lefever, T.W.2
Jackson, C.3
Tallarida, R.J.4
Walker, E.A.5
-
67
-
-
0026518794
-
Long-term weight control study, 1 (weeks 0-34) - The enhancement of behavior-modification, caloric restriction, and exercise by fenfluramine plus phentermine
-
Weintraub, M., Sundaresan, P. R., Madan, M., Schuster, B., Balder, A., Lasagna, L. and Cox, C. (1992). Long-term weight control study, 1 (weeks 0-34) - the enhancement of behavior-modification, caloric restriction, and exercise by fenfluramine plus phentermine. Clin. Pharmacol. Ther. 51, 586-594.
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 586-594
-
-
Weintraub, M.1
Sundaresan, P.R.2
Madan, M.3
Schuster, B.4
Balder, A.5
Lasagna, L.6
Cox, C.7
-
68
-
-
84865494008
-
Clinical investigations of antiobesity drugs
-
(ed. T. C. Kirkham and S. J. Cooper), . London: Academic Press
-
Wilding, J. (2007). Clinical investigations of antiobesity drugs. In Appetite and Body Weight (ed. T. C. Kirkham and S. J. Cooper), pp. 337-355. London: Academic Press.
-
(2007)
Appetite and Body Weight
, pp. 337-355
-
-
Wilding, J.1
-
69
-
-
84864703254
-
New drugs for diabetes: Glucagon-like peptide 1 analogues
-
Wilding, J. P. H. and Hardy, K. (2011). New drugs for diabetes: glucagon-like peptide 1 analogues. BMJ 342, 343-346.
-
(2011)
BMJ
, vol.342
, pp. 343-346
-
-
Wilding, J.P.H.1
Hardy, K.2
-
70
-
-
33749597936
-
A self-regulation program for maintenance of weight loss
-
DOI 10.1056/NEJMoa061883
-
Wing, R. R., Tate, D. F., Gorin, A. A., Raynor, H. A. and Fava, J. L. (2006). A selfregulation program for maintenance of weight loss. N. Eng. J. Med. 355, 1563-1571. (Pubitemid 44547807)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.15
, pp. 1563-1571
-
-
Wing, R.R.1
Tate, D.F.2
Gorin, A.A.3
Raynor, H.A.4
Fava, J.L.5
-
71
-
-
33845328809
-
Pancreatic signals controlling food intake; insulin, glucagon and amylin
-
DOI 10.1098/rstb.2006.1858
-
Woods, S. C., Lutz, T. A., Geary, N. and Langhans, W. (2006). Pancreatic signals controlling food intake: insulin, glucagon and amylin. Philos. Trans. R. Soc. Lond. B Biol. Sci. 361, 1219-1235. (Pubitemid 44882937)
-
(2006)
Philosophical Transactions of the Royal Society B: Biological Sciences
, vol.361
, Issue.1471
, pp. 1219-1235
-
-
Woods, S.C.1
Lutz, T.A.2
Geary, N.3
Langhans, W.4
|