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Volumn 29, Issue 4, 2006, Pages 277-302

Safety of drug therapies used for weight loss and treatment of obesity

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DINITROPHENOL; AMFEPRAMONE; AMINOREX; AMPHETAMINE; ANOREXIGENIC AGENT; CAFFEINE; DEXAMPHETAMINE; DEXFENFLURAMINE; EPHEDRINE; FENFLURAMINE; FLUOXETINE; HYDROXYCUT; LIPOKINETIX; MAZINDOL; METABOLIFE 356; METHAMPHETAMINE; NOREPHEDRINE; PHENTERMINE; PHENYLPROPANOLAMINE; PLACEBO; RIMONABANT; SEROTONIN UPTAKE INHIBITOR; SIBUTRAMINE; TETRAHYDROLIPSTATIN; THYROID HORMONE;

EID: 33645468559     PISSN: 01145916     EISSN: 01145916     Source Type: Journal    
DOI: 10.2165/00002018-200629040-00001     Document Type: Review
Times cited : (126)

References (244)
  • 1
    • 0032697493 scopus 로고    scopus 로고
    • The spread of the obesity epidemic in the United States 1991-1998
    • Mokdad AH, Serdula MK, Dietz WH, et al. The spread of the obesity epidemic in the United States 1991-1998. JAMA 1999; 282: 1519-22
    • (1999) JAMA , vol.282 , pp. 1519-1522
    • Mokdad, A.H.1    Serdula, M.K.2    Dietz, W.H.3
  • 2
    • 0035850402 scopus 로고    scopus 로고
    • The continuing epidemics of obesity and diabetes in the United States
    • Mokdad AH, Bowman BA, Ford ES, et al. The continuing epidemics of obesity and diabetes in the United States. JAMA 2001; 286: 1195-200
    • (2001) JAMA , vol.286 , pp. 1195-1200
    • Mokdad, A.H.1    Bowman, B.A.2    Ford, E.S.3
  • 3
    • 0037048669 scopus 로고    scopus 로고
    • Prevalence and trends in obesity amongst US adults, 1999-2000
    • Flegal KM, Carroll MD, Ogden CL, et al. Prevalence and trends in obesity amongst US adults, 1999-2000. JAMA 2002; 288: 1723-7
    • (2002) JAMA , vol.288 , pp. 1723-1727
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3
  • 5
    • 0035806044 scopus 로고    scopus 로고
    • Losing the battle of the bulge: Causes and consequences of increasing obesity
    • Eckersley RM. Losing the battle of the bulge: causes and consequences of increasing obesity. Med J Aust 2001; 174: 590-2
    • (2001) Med J Aust , vol.174 , pp. 590-592
    • Eckersley, R.M.1
  • 6
    • 0035806199 scopus 로고    scopus 로고
    • Obesity: Definitely a growing concern
    • Baur LA. Obesity: definitely a growing concern. Med J Aust 2001; 174: 553-4
    • (2001) Med J Aust , vol.174 , pp. 553-554
    • Baur, L.A.1
  • 7
    • 0028064561 scopus 로고
    • Incidence and progression of osteoarthritis in women with unilateral knee disease in the general population: The effect of obesity
    • Spector TD, Hart DJ, Doyle D. Incidence and progression of osteoarthritis in women with unilateral knee disease in the general population: the effect of obesity. Ann Rheum Dis 1994; 53: 565-8
    • (1994) Ann Rheum Dis , vol.53 , pp. 565-568
    • Spector, T.D.1    Hart, D.J.2    Doyle, D.3
  • 8
    • 0029961095 scopus 로고    scopus 로고
    • Overweight, underweight, and mortality: A prospective study of 48287 men and women
    • Seidel JC, Verschuren WM, Vanleer EM, et al. Overweight, underweight, and mortality: a prospective study of 48287 men and women. Arch Intern Med 1996; 156: 958-63
    • (1996) Arch Intern Med , vol.156 , pp. 958-963
    • Seidel, J.C.1    Verschuren, W.M.2    Vanleer, E.M.3
  • 9
    • 0033533859 scopus 로고    scopus 로고
    • Body-mass index and mortality in a prospective cohort of US adults
    • Calle EE, Thun NJ, Petrelli JM, et al. Body-mass index and mortality in a prospective cohort of US adults. N Engl J Med 1999; 341: 1097-105
    • (1999) N Engl J Med , vol.341 , pp. 1097-1105
    • Calle, E.E.1    Thun, N.J.2    Petrelli, J.M.3
  • 10
    • 0001193224 scopus 로고    scopus 로고
    • AACE/ACE position statement on the prevention, diagnosis and treatment of obesity (1998 revision)
    • AACE/ACE position statement on the prevention, diagnosis and treatment of obesity (1998 revision). Endocr Pract 1998; 4: 297-330
    • (1998) Endocr Pract , vol.4 , pp. 297-330
  • 11
    • 0037048167 scopus 로고    scopus 로고
    • Overweight and obesity as determinants of cardiovascular risk
    • Wilson PWF, D'Agostino RB, Sullivan L, et al. Overweight and obesity as determinants of cardiovascular risk. Arch Intern Med 2002; 162: 1867-72
    • (2002) Arch Intern Med , vol.162 , pp. 1867-1872
    • Wilson, P.W.F.1    D'Agostino, R.B.2    Sullivan, L.3
  • 12
    • 0031712986 scopus 로고    scopus 로고
    • Outcomes of pharmacological and surgical treatment for obesity
    • Cerulli J, Malone M. Outcomes of pharmacological and surgical treatment for obesity. Pharmacoeconomics 1998; 14: 269-83
    • (1998) Pharmacoeconomics , vol.14 , pp. 269-283
    • Cerulli, J.1    Malone, M.2
  • 13
    • 0035169826 scopus 로고    scopus 로고
    • The effects of orlistat on weight and on serum lipids in obese patients with hypercholesterolemia: A randomized, double-blind, placebo controlled, multicentre study
    • Muls E, Kolanowski J, Scheen A, et al. The effects of orlistat on weight and on serum lipids in obese patients with hypercholesterolemia: a randomized, double-blind, placebo controlled, multicentre study. Int J Obes 2001; 25: 1713-21
    • (2001) Int J Obes , vol.25 , pp. 1713-1721
    • Muls, E.1    Kolanowski, J.2    Scheen, A.3
  • 14
    • 0346250180 scopus 로고    scopus 로고
    • Long-term pharmacotherapy for overweight and obesity: A systematic review and meta-analysis of randomized controlled trials
    • Padwal R, Li SK. Long-term pharmacotherapy for overweight and obesity: a systematic review and meta-analysis of randomized controlled trials. Int J Obes Relat Metab Disord 2003; 27: 1437-46
    • (2003) Int J Obes Relat Metab Disord , vol.27 , pp. 1437-1446
    • Padwal, R.1    Li, S.K.2
  • 15
    • 4544237550 scopus 로고    scopus 로고
    • Clinical pharmacotherapy for obesity: Current drugs and those in advanced development
    • Halford JCG. Clinical pharmacotherapy for obesity: current drugs and those in advanced development. Curr Drugs Targets 2004; 5: 637-46
    • (2004) Curr Drugs Targets , vol.5 , pp. 637-646
    • Halford, J.C.G.1
  • 16
    • 1042303480 scopus 로고    scopus 로고
    • XENical in the prevention of Diabetes in Obese Subjects (XENDOS) study
    • Torgerson JA, Hauptman J, Boldrin MN, et al. XENical in the prevention of Diabetes in Obese Subjects (XENDOS) study. Diabetes Care 2004; 27: 155-61
    • (2004) Diabetes Care , vol.27 , pp. 155-161
    • Torgerson, J.A.1    Hauptman, J.2    Boldrin, M.N.3
  • 17
    • 0034890568 scopus 로고    scopus 로고
    • Long-term pharmacotherapy of obesity 2000: A review of efficacy and safety
    • Glazer G. Long-term pharmacotherapy of obesity 2000: a review of efficacy and safety. Arch Intern Med 2001; 161: 1814-24
    • (2001) Arch Intern Med , vol.161 , pp. 1814-1824
    • Glazer, G.1
  • 18
    • 0026517115 scopus 로고
    • Long-term weight control: The National Heart, Lung, and Blood Institute funded multimodal intervention study
    • Weintraub M. Long-term weight control: the National Heart, Lung, and Blood Institute funded multimodal intervention study. Clin Pharmacol Ther 1992; 51 Suppl.: 581-646
    • (1992) Clin Pharmacol Ther , vol.51 , Issue.SUPPL. , pp. 581-646
    • Weintraub, M.1
  • 19
    • 0037630406 scopus 로고    scopus 로고
    • Pharmacological therapy of obesity: Past present and future
    • Weigle DS. Pharmacological therapy of obesity: past present and future. J Clin Endocrinol Metab 2003; 88: 2462-9
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2462-2469
    • Weigle, D.S.1
  • 20
    • 0033942504 scopus 로고    scopus 로고
    • Thyroid hormones and treatment of obesity
    • Krotkiewski M. Thyroid hormones and treatment of obesity. Internat J Obes 2000; 24 Suppl. 2: S116-9
    • (2000) Internat J Obes , vol.24 , Issue.2 SUPPL.
    • Krotkiewski, M.1
  • 21
    • 0028347294 scopus 로고
    • Desicated thyroid in a nutritional supplement
    • Eliason BC, Doenier JA, Nuhlicek DN, et al. Desicated thyroid in a nutritional supplement. J Fam Pract 1994; 38: 287-8
    • (1994) J Fam Pract , vol.38 , pp. 287-288
    • Eliason, B.C.1    Doenier, J.A.2    Nuhlicek, D.N.3
  • 22
    • 0014137233 scopus 로고
    • A controlled study of thyroid analogs in the therapy of obesity
    • Gwinup G, Poucher R. A controlled study of thyroid analogs in the therapy of obesity. Am J Med Sci 1967; 254: 416-20
    • (1967) Am J Med Sci , vol.254 , pp. 416-420
    • Gwinup, G.1    Poucher, R.2
  • 23
    • 0016431126 scopus 로고
    • Therapy of obesity with hormones
    • Rivlin RS. Therapy of obesity with hormones. N Eng J Med 1975; 292: 26-9
    • (1975) N Eng J Med , vol.292 , pp. 26-29
    • Rivlin, R.S.1
  • 24
    • 1642268123 scopus 로고    scopus 로고
    • Treating obesity: Pharmacology and energy expenditure
    • Clapham JC. Treating obesity: pharmacology and energy expenditure. Curr Drug Targets 2004; 5: 309-23
    • (2004) Curr Drug Targets , vol.5 , pp. 309-323
    • Clapham, J.C.1
  • 25
    • 0017162523 scopus 로고
    • Pharmacological approaches to treat-ing the obese patient
    • Bray GA, Greenway FL. Pharmacological approaches to treat-ing the obese patient. Clin Endocrinol Metab 1976; 5: 455-79
    • (1976) Clin Endocrinol Metab , vol.5 , pp. 455-479
    • Bray, G.A.1    Greenway, F.L.2
  • 26
    • 24644477445 scopus 로고    scopus 로고
    • Anorectics on trial: A half century of federal regulation of prescription appetite suppressants
    • Colman E. Anorectics on trial: a half century of federal regulation of prescription appetite suppressants. Ann Intern Med 2005; 143: 380-5
    • (2005) Ann Intern Med , vol.143 , pp. 380-385
    • Colman, E.1
  • 27
    • 0014259075 scopus 로고
    • Effects of chronic administration of the amphetamines and other stimulants on behaviour
    • Kosman ME, Unna KR. Effects of chronic administration of the amphetamines and other stimulants on behaviour. Clin Pharmacol Ther 1968; 9: 240-8
    • (1968) Clin Pharmacol Ther , vol.9 , pp. 240-248
    • Kosman, M.E.1    Unna, K.R.2
  • 28
    • 0029587695 scopus 로고
    • Appetite suppressants and primary pulmonary hypertension in the United Kingdom
    • Thomas SHL, Butt AY, Corris PA, et al. Appetite suppressants and primary pulmonary hypertension in the United Kingdom. Br Heart J 1995; 74: 660-3
    • (1995) Br Heart J , vol.74 , pp. 660-663
    • Thomas, S.H.L.1    Butt, A.Y.2    Corris, P.A.3
  • 29
    • 0025105618 scopus 로고
    • Adverse drug effects attributed to phenylpropanolamine: A review of 142 case reports
    • Lake CR, Gallant S, Masson E, et al. Adverse drug effects attributed to phenylpropanolamine: a review of 142 case reports. Am J Med 1990; 89: 195-208
    • (1990) Am J Med , vol.89 , pp. 195-208
    • Lake, C.R.1    Gallant, S.2    Masson, E.3
  • 30
    • 19944407650 scopus 로고    scopus 로고
    • Temporal trends in the number of reported cases of pulmonary hypertension and use of anorexigens, antidepressants, and amphetamines, 1998-2001
    • Langleben D, Walker AM, Korelitz JJ, et al. Temporal trends in the number of reported cases of pulmonary hypertension and use of anorexigens, antidepressants, and amphetamines, 1998-2001 [abstract]. Am J Respir Crit Care Med 2004; 169: A171
    • (2004) Am J Respir Crit Care Med , vol.169
    • Langleben, D.1    Walker, A.M.2    Korelitz, J.J.3
  • 31
    • 0019431759 scopus 로고
    • Amphetamine-like reactions to phenylpropanolamine
    • Dietz AJ. Amphetamine-like reactions to phenylpropanolamine. JAMA 1981; 245: 601-2
    • (1981) JAMA , vol.245 , pp. 601-602
    • Dietz, A.J.1
  • 32
    • 0029591115 scopus 로고
    • Psychotic episode related to phenylpropanolamine and amantadine in a healthy female
    • Stroe AE, Hall J, Amin F. Psychotic episode related to phenylpropanolamine and amantadine in a healthy female [letter]. Gen Hosp Psychiatry 1995; 17: 457-8
    • (1995) Gen Hosp Psychiatry , vol.17 , pp. 457-458
    • Stroe, A.E.1    Hall, J.2    Amin, F.3
  • 33
    • 0034082009 scopus 로고    scopus 로고
    • Exacerbation of psychosis by phenylpropanolamine
    • Goodhue A, Bartel RL, Smith NB. Exacerbation of psychosis by phenylpropanolamine [letter]. Am J Psychiatry 2000; 157: 1021-2
    • (2000) Am J Psychiatry , vol.157 , pp. 1021-1022
    • Goodhue, A.1    Bartel, R.L.2    Smith, N.B.3
  • 34
    • 0021058818 scopus 로고
    • Plasma phentermine levels, weight loss and side-effects
    • Douglas A, Douglas JG, Robertson CE, et al. Plasma phentermine levels, weight loss and side-effects. Internat J Obes 1983; 7: 591-5
    • (1983) Internat J Obes , vol.7 , pp. 591-595
    • Douglas, A.1    Douglas, J.G.2    Robertson, C.E.3
  • 35
    • 0001661402 scopus 로고
    • Comparison of continuous and intermittent anorectic therapy in obesity
    • Munro JF, MacCuish AC, Wilson EM, et al. Comparison of continuous and intermittent anorectic therapy in obesity. Br Med J 1968; 1: 352-4
    • (1968) Br Med J , vol.1 , pp. 352-354
    • Munro, J.F.1    MacCuish, A.C.2    Wilson, E.M.3
  • 36
    • 0015428967 scopus 로고
    • Phentermine resin as an adjunct in medical weight reduction: A controlled randomized double-blind prospective study
    • Truant AP, Olon LP, Cobb S. Phentermine resin as an adjunct in medical weight reduction: a controlled randomized double-blind prospective study. Curr Ther Res Clin Exp 1972; 14: 726-38
    • (1972) Curr Ther Res Clin Exp , vol.14 , pp. 726-738
    • Truant, A.P.1    Olon, L.P.2    Cobb, S.3
  • 37
    • 16844379087 scopus 로고    scopus 로고
    • Pharmacological therapies for obesity
    • Kaplan LM. Pharmacological therapies for obesity. Gastroenterol Clin North Am 2005; 34: 91-104
    • (2005) Gastroenterol Clin North Am , vol.34 , pp. 91-104
    • Kaplan, L.M.1
  • 38
    • 10544235698 scopus 로고    scopus 로고
    • Long-term pharmacotherapy in the management of obesity
    • National Task Force on the Prevention and Treatment of Obesity. Long-term pharmacotherapy in the management of obesity. JAMA 1996; 276: 1907-15
    • (1996) JAMA , vol.276 , pp. 1907-1915
  • 39
    • 0030953225 scopus 로고    scopus 로고
    • The pharmacological approach to the treatment of obesity
    • Weiser M, Frishman WH, Michaelson MD, et al. The pharmacological approach to the treatment of obesity. J Clin Pharmacol 1997; 37: 453-73
    • (1997) J Clin Pharmacol , vol.37 , pp. 453-473
    • Weiser, M.1    Frishman, W.H.2    Michaelson, M.D.3
  • 40
    • 0032990098 scopus 로고    scopus 로고
    • A risk-benefit assessment of anti-obesity drugs
    • Kolanowski J. A risk-benefit assessment of anti-obesity drugs. Drug Saf 1999; 20: 119-31
    • (1999) Drug Saf , vol.20 , pp. 119-131
    • Kolanowski, J.1
  • 41
    • 0019500942 scopus 로고
    • Ephedrine as an anorectic: The story of the 'Elisinore pill'
    • Malchow-Moller A, Larsen S, Hey H, et al. Ephedrine as an anorectic: the story of the 'Elisinore pill'. Internat J Obes 1981; 5: 183-7
    • (1981) Internat J Obes , vol.5 , pp. 183-187
    • Malchow-Moller, A.1    Larsen, S.2    Hey, H.3
  • 42
    • 0018771559 scopus 로고
    • Diethylpropion and paranoid psychosis
    • Petursson H. Diethylpropion and paranoid psychosis. Aust N Z J Psychiatry 1979; 13: 67-8
    • (1979) Aust N Z J Psychiatry , vol.13 , pp. 67-68
    • Petursson, H.1
  • 43
    • 0023986984 scopus 로고
    • Diethylpropion hydrochloride-induced psychosis
    • Brooke D, Kerwin R, Lloyd K. Diethylpropion hydrochloride-induced psychosis. Br J Psychiatry 1988; 152: 572-3
    • (1988) Br J Psychiatry , vol.152 , pp. 572-573
    • Brooke, D.1    Kerwin, R.2    Lloyd, K.3
  • 44
    • 0023946167 scopus 로고
    • Diethylpropion and psychosis
    • Carney MW. Diethylpropion and psychosis. Clin Neuropharmacol 1988; 11: 183-8
    • (1988) Clin Neuropharmacol , vol.11 , pp. 183-188
    • Carney, M.W.1
  • 45
    • 0027528646 scopus 로고
    • Psychosis following readministration of diethylproprion: A possible role for kindling?
    • Little JD, Romans SE. Psychosis following readministration of diethylproprion: a possible role for kindling? Int Clin Psychopharmacol 1993; 8: 67-70
    • (1993) Int Clin Psychopharmacol , vol.8 , pp. 67-70
    • Little, J.D.1    Romans, S.E.2
  • 46
    • 0033547771 scopus 로고    scopus 로고
    • Aminorex to fen/phen: An epidemic foretold
    • Fishman AP. Aminorex to fen/phen: an epidemic foretold. Circulation 1999; 99: 156-61
    • (1999) Circulation , vol.99 , pp. 156-161
    • Fishman, A.P.1
  • 47
    • 0032055849 scopus 로고    scopus 로고
    • Pharmacoepidemiology report. Aminorex, dexfenfluramine and primary pulmonary hypertension
    • Kramer MS, Lane DA. Pharmacoepidemiology report. Aminorex, dexfenfluramine and primary pulmonary hypertension. J Clin Epidemiol 1998; 51: 361-4
    • (1998) J Clin Epidemiol , vol.51 , pp. 361-364
    • Kramer, M.S.1    Lane, D.A.2
  • 48
    • 0029401367 scopus 로고
    • Clinical studies with mazindol
    • Inoue S. Clinical studies with mazindol. Obes Res 1995; 3 (Suppl. 4): 549-52
    • (1995) Obes Res , vol.3 , Issue.4 SUPPL. , pp. 549-552
    • Inoue, S.1
  • 49
    • 0016209005 scopus 로고
    • Mazindol in obesity with known cardiac disease: A clinical evaluation
    • Bradley MH, Blum NJ, Scheib RJ. Mazindol in obesity with known cardiac disease: a clinical evaluation. J Intern Med Res 1976; 2: 347-9
    • (1976) J Intern Med Res , vol.2 , pp. 347-349
    • Bradley, M.H.1    Blum, N.J.2    Scheib, R.J.3
  • 50
    • 0026604769 scopus 로고
    • Clinical and basic aspects of an anorexiant mazindol as an antiobesity agent in Japan
    • Inoue S, Egawa M, Satoh S, et al. Clinical and basic aspects of an anorexiant mazindol as an antiobesity agent in Japan. Am J Clin Nutr 1992; 55: 199S-202S
    • (1992) Am J Clin Nutr , vol.55
    • Inoue, S.1    Egawa, M.2    Satoh, S.3
  • 51
    • 0034095170 scopus 로고    scopus 로고
    • Delayed onset of pulmonary hypertension associated with an appetite suppressant, mazindol: A case report
    • Hagiwara M, Tsuchida A, Hyakkoku M, et al. Delayed onset of pulmonary hypertension associated with an appetite suppressant, mazindol: a case report. Jpn Circ J 2000; 64: 218-21
    • (2000) Jpn Circ J , vol.64 , pp. 218-221
    • Hagiwara, M.1    Tsuchida, A.2    Hyakkoku, M.3
  • 52
    • 0034700454 scopus 로고    scopus 로고
    • Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids
    • Haller CA, Benowitz NL. Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. N Engl J Med 2000; 343: 1833-8
    • (2000) N Engl J Med , vol.343 , pp. 1833-1838
    • Haller, C.A.1    Benowitz, N.L.2
  • 53
    • 0037467338 scopus 로고    scopus 로고
    • Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: A meta-analysis
    • Shekelle PG, Hardy ML, Morton SC, et al. Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: a meta-analysis. JAMA 2003; 289: 1537-45
    • (2003) JAMA , vol.289 , pp. 1537-1545
    • Shekelle, P.G.1    Hardy, M.L.2    Morton, S.C.3
  • 54
    • 0035427921 scopus 로고    scopus 로고
    • The safety and efficacy of pharmaceutical and herbal caffiene and ephedrine use as a weight loss agent
    • Greenway FL. The safety and efficacy of pharmaceutical and herbal caffiene and ephedrine use as a weight loss agent. Obes Rev 2001; 2: 199-211
    • (2001) Obes Rev , vol.2 , pp. 199-211
    • Greenway, F.L.1
  • 57
    • 0028151299 scopus 로고
    • Long-term weight loss: The effect of pharmacologic agents
    • Goldstein DJ, Potvin JH. Long-term weight loss: the effect of pharmacologic agents. Am J Clin Nutr 1994: 60: 647-57
    • (1994) Am J Clin Nutr , vol.60 , pp. 647-657
    • Goldstein, D.J.1    Potvin, J.H.2
  • 58
    • 0016816599 scopus 로고
    • Fenfluramine: A review of its pharmacological properties and therapeutic efficacy in obesity
    • Pinder RM, Brogden RN, Sawyer PR, et al. Fenfluramine: a review of its pharmacological properties and therapeutic efficacy in obesity. Drugs 1975; 10: 241-323
    • (1975) Drugs , vol.10 , pp. 241-323
    • Pinder, R.M.1    Brogden, R.N.2    Sawyer, P.R.3
  • 59
    • 0030852548 scopus 로고    scopus 로고
    • Dexfenfluramine hydrochloride: An anorexigenic agent
    • Bever KA, Perry PJ. Dexfenfluramine hydrochloride: an anorexigenic agent. Am J Heath Syst Pharm 1997; 54: 2059-72
    • (1997) Am J Heath Syst Pharm , vol.54 , pp. 2059-2072
    • Bever, K.A.1    Perry, P.J.2
  • 60
    • 0029825160 scopus 로고    scopus 로고
    • Dexfenfluramine: An updated review of its therapeutic use in the management of obesity
    • Davis R, Faulds D. Dexfenfluramine: an updated review of its therapeutic use in the management of obesity. Drugs 1996; 52: 696-724
    • (1996) Drugs , vol.52 , pp. 696-724
    • Davis, R.1    Faulds, D.2
  • 61
    • 0026655476 scopus 로고
    • Dexfenfluramine in the treatment of severe obesity: A placebo-controlled investigation of the effects on weight loss, cardiovascular risk factors, food intake and eating behaviour
    • Mathus-Vliegen EMH, Van de Voorde K, Kok AME, et al. Dexfenfluramine in the treatment of severe obesity: a placebo-controlled investigation of the effects on weight loss, cardiovascular risk factors, food intake and eating behaviour. J Intern Med 1992; 232: 199-27
    • (1992) J Intern Med , vol.232 , pp. 199-227
    • Mathus-Vliegen, E.M.H.1    Van De Voorde, K.2    Kok, A.M.E.3
  • 62
    • 0030822962 scopus 로고    scopus 로고
    • Psychotic episode associated with dexfenfluramine
    • Preval H, Pakyurek AM. Psychotic episode associated with dexfenfluramine [letter]. Am J Psychiatry 1997; 154: 1624-5
    • (1997) Am J Psychiatry , vol.154 , pp. 1624-1625
    • Preval, H.1    Pakyurek, A.M.2
  • 63
    • 15944367788 scopus 로고    scopus 로고
    • Meta-analysis: Pharmacologic treatment of obesity
    • Li Z, Maglione M, Tu W, et al. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med 2005; 142: 532-46
    • (2005) Ann Intern Med , vol.142 , pp. 532-546
    • Li, Z.1    Maglione, M.2    Tu, W.3
  • 64
    • 0037279371 scopus 로고    scopus 로고
    • Weight management and current options in pharmacotherapy: Orlistat and sibutramine
    • Leung WYS, Thomas GN, Chan JCN, et al. Weight management and current options in pharmacotherapy: orlistat and sibutramine. Clin Ther 2003; 25: 58-80
    • (2003) Clin Ther , vol.25 , pp. 58-80
    • Leung, W.Y.S.1    Thomas, G.N.2    Chan, J.C.N.3
  • 65
    • 0032434821 scopus 로고    scopus 로고
    • Sibutramine: A review of its contribution to the management of obesity
    • McNeely W, Goa KL. Sibutramine: a review of its contribution to the management of obesity. Drugs 1998; 56: 1093-124
    • (1998) Drugs , vol.56 , pp. 1093-1124
    • McNeely, W.1    Goa, K.L.2
  • 66
    • 0344874623 scopus 로고    scopus 로고
    • A benefit-risk assessment of sibutramine in the management of obesity
    • Nisoli E, Carruba MO. A benefit-risk assessment of sibutramine in the management of obesity. Drug Saf 2003; 26: 1027-48
    • (2003) Drug Saf , vol.26 , pp. 1027-1048
    • Nisoli, E.1    Carruba, M.O.2
  • 67
    • 0034710218 scopus 로고    scopus 로고
    • Efficacy and safety of sibutramine in obese white and African-American patients with hypertension: A 1-year, double-blind, placebo-controlled, multicentre trial
    • McMahon FG, Fujioka K, Singh BN, et al. Efficacy and safety of sibutramine in obese white and African-American patients with hypertension: a 1-year, double-blind, placebo-controlled, multicentre trial. Arch Intern Med 2000; 160: 2185-91
    • (2000) Arch Intern Med , vol.160 , pp. 2185-2191
    • McMahon, F.G.1    Fujioka, K.2    Singh, B.N.3
  • 68
    • 0033090465 scopus 로고    scopus 로고
    • Sibutramine produces dose-related weight loss
    • Bray GA, Blackburn GL, Ferguson JM, et al. Sibutramine produces dose-related weight loss. Obes Res 1999; 7: 189-98
    • (1999) Obes Res , vol.7 , pp. 189-198
    • Bray, G.A.1    Blackburn, G.L.2    Ferguson, J.M.3
  • 69
    • 0033082197 scopus 로고    scopus 로고
    • Long-term maintenance of weight loss after very-low-calorie diet: Efficacy and tolerability of sibutramine
    • Apfelbaum M, Vague P, Ziegler O, et al. Long-term maintenance of weight loss after very-low-calorie diet: Efficacy and tolerability of sibutramine. Am J Med 1999; 106: 179-84
    • (1999) Am J Med , vol.106 , pp. 179-184
    • Apfelbaum, M.1    Vague, P.2    Ziegler, O.3
  • 70
    • 0032990098 scopus 로고    scopus 로고
    • A risk-benefit assessment of anti-obesity drugs
    • Kolanowski J. A risk-benefit assessment of anti-obesity drugs. Drug Saf 1999; 20: 119-31
    • (1999) Drug Saf , vol.20 , pp. 119-131
    • Kolanowski, J.1
  • 71
    • 85047695511 scopus 로고    scopus 로고
    • Pharmacotherapy for obesity: A quantitative analysis of four decades of published randomised clinical trials
    • Haddock CK, Poston WSC, Dill PL, et al. Pharmacotherapy for obesity: a quantitative analysis of four decades of published randomised clinical trials. Int J Obes 2002; 26: 262-73
    • (2002) Int J Obes , vol.26 , pp. 262-273
    • Haddock, C.K.1    Poston, W.S.C.2    Dill, P.L.3
  • 73
    • 0024446507 scopus 로고
    • International trial of long-term dexfenfluramine in obesity
    • Guy-Grand B, Crepaldi G, Lefebvre P, et al. International trial of long-term dexfenfluramine in obesity. Lancet 1989; II: 1142-4
    • (1989) Lancet , vol.2 , pp. 1142-1144
    • Guy-Grand, B.1    Crepaldi, G.2    Lefebvre, P.3
  • 74
    • 0028222739 scopus 로고
    • Fluoxetine: A randomised clinical trial in the treatment of obesity
    • Goldstein DJ, Rampey AH, Enas GG, et al. Fluoxetine: a randomised clinical trial in the treatment of obesity. Int J Obes Relat Metab Disord 1994; 18: 129-35
    • (1994) Int J Obes Relat Metab Disord , vol.18 , pp. 129-135
    • Goldstein, D.J.1    Rampey, A.H.2    Enas, G.G.3
  • 75
    • 0034516930 scopus 로고    scopus 로고
    • Effect of sibutramine on weight maintenance after weight loss: A randomised trial
    • James WPT, Astrup A, Finer N, et al. Effect of sibutramine on weight maintenance after weight loss: a randomised trial. Lancet 2000; 356: 2119-25
    • (2000) Lancet , vol.356 , pp. 2119-2125
    • James, W.P.T.1    Astrup, A.2    Finer, N.3
  • 76
    • 0035913584 scopus 로고    scopus 로고
    • Long-term weight loss with sibutramine: A randomized controlled trial
    • Wirth A, Krause J. Long-term weight loss with sibutramine: a randomized controlled trial. JAMA 2001; 286: 1331-9
    • (2001) JAMA , vol.286 , pp. 1331-1339
    • Wirth, A.1    Krause, J.2
  • 77
    • 0033585499 scopus 로고    scopus 로고
    • Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: A randomised controlled trial
    • Davidson MH, Hauptman J, DiGirolamo M, et al. Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomised controlled trial. JAMA 1999; 281: 235-42
    • (1999) JAMA , vol.281 , pp. 235-242
    • Davidson, M.H.1    Hauptman, J.2    DiGirolamo, M.3
  • 78
    • 0032543870 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients
    • European Multicentre Orlistat Study Group
    • Sjöström L, Rissanen A, Anderson T, et al. Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European Multicentre Orlistat Study Group. Lancet 1998; 352: 167-73
    • (1998) Lancet , vol.352 , pp. 167-173
    • Sjöström, L.1    Rissanen, A.2    Anderson, T.3
  • 79
    • 0033629936 scopus 로고    scopus 로고
    • Weight loss, weight maintenance, and improved cardiovascular risk factors after 2 years treatment with orlistat for obesity
    • European Orlistat Obesity Study Group
    • Rossner S, Sjostrom L, Noack R, et al. Weight loss, weight maintenance, and improved cardiovascular risk factors after 2 years treatment with orlistat for obesity. European Orlistat Obesity Study Group. Obes Res 2000; 8: 49-61
    • (2000) Obes Res , vol.8 , pp. 49-61
    • Rossner, S.1    Sjostrom, L.2    Noack, R.3
  • 80
    • 0036382146 scopus 로고    scopus 로고
    • Pharmacotherapy of obesity: Currently marketed and upcoming agents
    • Bays H, Dujovne C. Pharmacotherapy of obesity: currently marketed and upcoming agents. Am J Cardiovasc Drugs 2002; 2: 245-53
    • (2002) Am J Cardiovasc Drugs , vol.2 , pp. 245-253
    • Bays, H.1    Dujovne, C.2
  • 81
    • 0036205406 scopus 로고    scopus 로고
    • Ephedra/ephedrine: Cardiovascular and CNS effects
    • Wooltorton E, Sibbald B. Ephedra/ephedrine: cardiovascular and CNS effects. Can Med Assoc J 2002; 166: 633
    • (2002) Can Med Assoc J , vol.166 , pp. 633
    • Wooltorton, E.1    Sibbald, B.2
  • 82
    • 0034700445 scopus 로고    scopus 로고
    • The FDA, regulation, and the risk of stroke
    • Fleming GA. The FDA, regulation, and the risk of stroke. N Engl J Med 2000; 343: 1886-7
    • (2000) N Engl J Med , vol.343 , pp. 1886-1887
    • Fleming, G.A.1
  • 83
    • 0036360475 scopus 로고    scopus 로고
    • Regulatory decisions in a globalised world: The domino effect of phenylpropanolamine withdrawal in Latin America
    • Figueras A, Laporte JR. Regulatory decisions in a globalised world: the domino effect of phenylpropanolamine withdrawal in Latin America. Drug Saf 2002; 25 (10): 689-93
    • (2002) Drug Saf , vol.25 , Issue.10 , pp. 689-693
    • Figueras, A.1    Laporte, J.R.2
  • 84
    • 1542390739 scopus 로고    scopus 로고
    • Effect of sibutramine on weight loss and blood pressure: A meta-analysis of controlled trials
    • Kim SH, Lee YM, Jee SH, et al. Effect of sibutramine on weight loss and blood pressure: a meta-analysis of controlled trials. Obes Res 2003; 11: 1116-23
    • (2003) Obes Res , vol.11 , pp. 1116-1123
    • Kim, S.H.1    Lee, Y.M.2    Jee, S.H.3
  • 85
    • 0036098099 scopus 로고    scopus 로고
    • Obesity drug sibutramine (Meridia): Hypertension and cardiac arrhythmias
    • Wooltorton E. Obesity drug sibutramine (Meridia): hypertension and cardiac arrhythmias. CMAJ 2002; 166: 1307-8
    • (2002) CMAJ , vol.166 , pp. 1307-1308
    • Wooltorton, E.1
  • 87
    • 9444287592 scopus 로고    scopus 로고
    • Appetite-suppressant drugs and the risk of pulmonary hypertension
    • International Primary Pulmonary Hypertension Study Group
    • Abenhaim L, Moride Y, Brenot S, et al. Appetite-suppressant drugs and the risk of pulmonary hypertension. International Primary Pulmonary Hypertension Study Group. N Engl J Med 1996; 335: 609-16
    • (1996) N Engl J Med , vol.335 , pp. 609-616
    • Abenhaim, L.1    Moride, Y.2    Brenot, S.3
  • 88
    • 0032578279 scopus 로고    scopus 로고
    • Primary pulmonary hypertension
    • Gaine SP, Rubin LJ. Primary pulmonary hypertension. Lancet 1998; 352: 719-25
    • (1998) Lancet , vol.352 , pp. 719-725
    • Gaine, S.P.1    Rubin, L.J.2
  • 89
    • 0033547771 scopus 로고    scopus 로고
    • Aminorex to Fen/Phen: An epidemic foretold
    • Fishman AP. Aminorex to Fen/Phen: an epidemic foretold. Circulation 1999; 99: 156-61
    • (1999) Circulation , vol.99 , pp. 156-161
    • Fishman, A.P.1
  • 90
    • 0035057728 scopus 로고    scopus 로고
    • Anorectic drugs and pulmonary hypertension from the bedside to the bench
    • Michelakis ED, Weir EK. Anorectic drugs and pulmonary hypertension from the bedside to the bench. Am J Med Sci 2001; 321: 292-9
    • (2001) Am J Med Sci , vol.321 , pp. 292-299
    • Michelakis, E.D.1    Weir, E.K.2
  • 91
    • 0021986849 scopus 로고
    • Aminorex and pulmonary hypertension
    • Gurtner HP. Aminorex and pulmonary hypertension. Cor Vasa 1985; 27: 60-171
    • (1985) Cor Vasa , vol.27 , pp. 60-171
    • Gurtner, H.P.1
  • 92
    • 0031874883 scopus 로고    scopus 로고
    • Relearning the lessons of history: Anorexigens and pulmonary hypertension
    • Langleben D. Relearning the lessons of history: anorexigens and pulmonary hypertension. Chest 1998; 114: 55S-7S
    • (1998) Chest , vol.114
    • Langleben, D.1
  • 93
    • 0032055849 scopus 로고    scopus 로고
    • Aminorex, dexfenfluramine, and primary pulmonary hypertension
    • Kramer MS, Lane DA. Aminorex, dexfenfluramine, and primary pulmonary hypertension. J Clin Epidemiol 1998; 51: 361-4
    • (1998) J Clin Epidemiol , vol.51 , pp. 361-364
    • Kramer, M.S.1    Lane, D.A.2
  • 94
    • 0019369617 scopus 로고
    • Pulmonary hypertension and fenfluramine
    • Douglas JD, Munro JF, Kitchin AH, et al. Pulmonary hypertension and fenfluramine. BMJ 1981; 283: 881-3
    • (1981) BMJ , vol.283 , pp. 881-883
    • Douglas, J.D.1    Munro, J.F.2    Kitchin, A.H.3
  • 95
    • 0035701278 scopus 로고    scopus 로고
    • Fenfluramines, idiopathic pulmonary primary hypertension and cardiac valve disorders: Facts and artifacts
    • Tellier P. Fenfluramines, idiopathic pulmonary primary hypertension and cardiac valve disorders: facts and artifacts. Ann Med Intern 2001; 152: 429-36
    • (2001) Ann Med Intern , vol.152 , pp. 429-436
    • Tellier, P.1
  • 96
    • 0021922182 scopus 로고
    • Long-term follow-up of pulmonary hypertension in patients with and without anorectic drug intake
    • Loogen F, Worth H, Schwan G, et al. Long-term follow-up of pulmonary hypertension in patients with and without anorectic drug intake. Cor Vasa 1985; 27: 111-24
    • (1985) Cor Vasa , vol.27 , pp. 111-124
    • Loogen, F.1    Worth, H.2    Schwan, G.3
  • 97
    • 0022574463 scopus 로고
    • Irreversible pulmonary hypertension after treatment with fenfluramine
    • McMurray J, Bloomfield P, Miller HC. Irreversible pulmonary hypertension after treatment with fenfluramine [letter]. BMJ 1986; 292: 239-40
    • (1986) BMJ , vol.292 , pp. 239-240
    • McMurray, J.1    Bloomfield, P.2    Miller, H.C.3
  • 98
    • 0030853476 scopus 로고    scopus 로고
    • Brief report: Fatal pulmonary hypertension associated with short-term use of fenfluramine and phentermine
    • Mark EJ, Patalas ED, Chang HT, et al. Brief report: fatal pulmonary hypertension associated with short-term use of fenfluramine and phentermine. N Engl J Med 1997; 337: 602-6
    • (1997) N Engl J Med , vol.337 , pp. 602-606
    • Mark, E.J.1    Patalas, E.D.2    Chang, H.T.3
  • 99
    • 0026599690 scopus 로고
    • Pulmonary hypertension and dexfenfluramine
    • Atanassoff PG, Weiss BM, Schmid ER, et al. Pulmonary hypertension and dexfenfluramine [letter]. Lancet 1992; 339: 436
    • (1992) Lancet , vol.339 , pp. 436
    • Atanassoff, P.G.1    Weiss, B.M.2    Schmid, E.R.3
  • 100
    • 0026599690 scopus 로고
    • Pulmonary hypertension and dexfenfluramine
    • Roche N, Labrune S, Braun J-M, et al. Pulmonary hypertension and dexfenfluramine [letter]. Lancet 1992; 339: 436-7
    • (1992) Lancet , vol.339 , pp. 436-437
    • Roche, N.1    Labrune, S.2    Braun, J.-M.3
  • 102
    • 0027135052 scopus 로고
    • Primary pulmonary hypertension and fenfluramine use
    • Brenot F, Herve P, Petitpretz P, et al. Primary pulmonary hypertension and fenfluramine use. Br Heart J 1993; 70: 537-41
    • (1993) Br Heart J , vol.70 , pp. 537-541
    • Brenot, F.1    Herve, P.2    Petitpretz, P.3
  • 103
    • 0030838580 scopus 로고    scopus 로고
    • Diet pills redux
    • Curfman GD. Diet pills redux. N Engl J Med 1997; 337: 629-30
    • (1997) N Engl J Med , vol.337 , pp. 629-630
    • Curfman, G.D.1
  • 104
    • 0031844306 scopus 로고    scopus 로고
    • High incidence of primary pulmonary hypertension associated with appetite suppressants in Belgium
    • Delcroix M, Kurz X, Walckiers D, et al. High incidence of primary pulmonary hypertension associated with appetite suppressants in Belgium. Eur Respir J 1998; 12: 271-6
    • (1998) Eur Respir J , vol.12 , pp. 271-276
    • Delcroix, M.1    Kurz, X.2    Walckiers, D.3
  • 105
    • 0034118327 scopus 로고    scopus 로고
    • Anorexigens and pulmonary hypertension in the United States: Results from the surveillance of North American Pulmonary Hypertension
    • Rich S, Rubin L, Walker AM, et al. Anorexigens and pulmonary hypertension in the United States: results from the surveillance of North American Pulmonary Hypertension. Chest 2000; 117: 870-4
    • (2000) Chest , vol.117 , pp. 870-874
    • Rich, S.1    Rubin, L.2    Walker, A.M.3
  • 106
    • 0034063651 scopus 로고    scopus 로고
    • Diet drug-related cardiac valve disease: The Mayo Clinic echocardiographic laboratory experience
    • Teramae CY, Connolly HM, Grogan M, et al. Diet drug-related cardiac valve disease: the Mayo Clinic echocardiographic laboratory experience. Mayo Clin Proc 2000; 75: 456-61
    • (2000) Mayo Clin Proc , vol.75 , pp. 456-461
    • Teramae, C.Y.1    Connolly, H.M.2    Grogan, M.3
  • 107
    • 0033545369 scopus 로고    scopus 로고
    • Primary pulmonary hypertension and anorectic drugs
    • Louis WJ. Primary pulmonary hypertension and anorectic drugs [letter]. N Engl J Med 1999; 340: 480-2
    • (1999) N Engl J Med , vol.340 , pp. 480-482
    • Louis, W.J.1
  • 108
    • 33748811261 scopus 로고    scopus 로고
    • Primary pulmonary hypertension and anorectic drugs
    • Abenhaim L, Rich S, Benichou J, et al. Primary pulmonary hypertension and anorectic drugs [letter]. N Engl J Med 1999; 340: 481-2
    • (1999) N Engl J Med , vol.340 , pp. 481-482
    • Abenhaim, L.1    Rich, S.2    Benichou, J.3
  • 109
    • 0034102915 scopus 로고    scopus 로고
    • Mortality from primary pulmonary hypertension in the United States, 1979-1996
    • Lilienfield DE, Rubin LJ. Mortality from primary pulmonary hypertension in the United States, 1979-1996. Chest 2000; 117: 796-800
    • (2000) Chest , vol.117 , pp. 796-800
    • Lilienfield, D.E.1    Rubin, L.J.2
  • 110
    • 0033747369 scopus 로고    scopus 로고
    • The age-adjusted mortality rate from primary pulmonary hypertension, in age range 20 to 54 years, did not increase during the years of peak 'phen-fen' use
    • Rothman RB. The age-adjusted mortality rate from primary pulmonary hypertension, in age range 20 to 54 years, did not increase during the years of peak 'phen-fen' use [letter]. Chest 2000; 118: 1516-7
    • (2000) Chest , vol.118 , pp. 1516-1517
    • Rothman, R.B.1
  • 111
    • 0029799509 scopus 로고    scopus 로고
    • Pharmacotherapy for obesity- Do the benefits outweigh the risk?
    • Manson JE, Faich GA. Pharmacotherapy for obesity- do the benefits outweigh the risk? N Engl J Med 1996; 335: 659-60
    • (1996) N Engl J Med , vol.335 , pp. 659-660
    • Manson, J.E.1    Faich, G.A.2
  • 112
    • 0029033224 scopus 로고
    • Increased plasma serotonin in primary pulmonary hypertension
    • Herve P, Launay JM, Scrbohaci ML, et al. Increased plasma serotonin in primary pulmonary hypertension. Am J Med 1995; 99: 249-54
    • (1995) Am J Med , vol.99 , pp. 249-254
    • Herve, P.1    Launay, J.M.2    Scrbohaci, M.L.3
  • 113
    • 0031720572 scopus 로고    scopus 로고
    • A role for potassium channels in smooth muscle cells and platelets in the etiology of primary pulmonary hypertension
    • Weir EK, Reeve HL, Johnson G, et al. A role for potassium channels in smooth muscle cells and platelets in the etiology of primary pulmonary hypertension. Chest 1998; 114 (3 Suppl.): 200S-4S
    • (1998) Chest , vol.114 , Issue.3 SUPPL.
    • Weir, E.K.1    Reeve, H.L.2    Johnson, G.3
  • 114
    • 0030967598 scopus 로고    scopus 로고
    • Fluoxetine is a safer alternative to fenfluramine in the medical treatment of obesity
    • Anchors M. Fluoxetine is a safer alternative to fenfluramine in the medical treatment of obesity. Arch Intern Med 1997; 157: 1270
    • (1997) Arch Intern Med , vol.157 , pp. 1270
    • Anchors, M.1
  • 115
    • 0033600538 scopus 로고    scopus 로고
    • Aminorex, fen-fluramine and chlorphentermine are serotonin transporter substrates: Implication for primary pulmonary hypertension
    • Rothman RB, Ayestas MA, Dersch CM, et al. Aminorex, fen-fluramine and chlorphentermine are serotonin transporter substrates: implication for primary pulmonary hypertension. Circulation 1999; 100: 869-75
    • (1999) Circulation , vol.100 , pp. 869-875
    • Rothman, R.B.1    Ayestas, M.A.2    Dersch, C.M.3
  • 116
    • 0742306737 scopus 로고    scopus 로고
    • Effects of the sibutramine therapy on pulmonary artery pressure in obese patients
    • Guven A, Koksal N, Cetinkaya A, et al. Effects of the sibutramine therapy on pulmonary artery pressure in obese patients. Diabetes Obes Metab 2004; 6: 50-5
    • (2004) Diabetes Obes Metab , vol.6 , pp. 50-55
    • Guven, A.1    Koksal, N.2    Cetinkaya, A.3
  • 117
    • 0042881023 scopus 로고    scopus 로고
    • Primary pulmonary hypertension after amfepramone (diethylpropion) with BMPR2 mutation
    • Abramowicz MJ, Van Haecke P, Demedts M, et al. Primary pulmonary hypertension after amfepramone (diethylpropion) with BMPR2 mutation. Eur Respir J 2003; 22: 560-2
    • (2003) Eur Respir J , vol.22 , pp. 560-562
    • Abramowicz, M.J.1    Van Haecke, P.2    Demedts, M.3
  • 118
    • 0031770719 scopus 로고    scopus 로고
    • Nitric oxide deficiency in fenfluramine- and dexfenfluramine- induced pulmonary hypertension
    • Archer SL, Djaballah K, Humbert M, et al. Nitric oxide deficiency in fenfluramine- and dexfenfluramine- induced pulmonary hypertension. Am J Respir Crit Care Med 1998; 158: 1061-7
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 1061-1067
    • Archer, S.L.1    Djaballah, K.2    Humbert, M.3
  • 119
    • 0345059064 scopus 로고    scopus 로고
    • Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension
    • Blanpain C, Le Poul E, Parma J, et al. Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension. Cardiovasc Res 2003; 60: 518-28
    • (2003) Cardiovasc Res , vol.60 , pp. 518-528
    • Blanpain, C.1    Le Poul, E.2    Parma, J.3
  • 120
    • 0030876952 scopus 로고    scopus 로고
    • Valvular heart disease associated with fenfluramine-phentermine
    • Connolly HM, Crary JL, McGoon MD, et al. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med 1997; 337: 581-8
    • (1997) N Engl J Med , vol.337 , pp. 581-588
    • Connolly, H.M.1    Crary, J.L.2    McGoon, M.D.3
  • 121
    • 0004341041 scopus 로고
    • Prevalence and clinical correlates of aortic and mitral regurgitation in a young adult population: The CARDIA study
    • Reid CL, Gardin JM, Yunis C, et al. Prevalence and clinical correlates of aortic and mitral regurgitation in a young adult population: the CARDIA study [abstract]. Circulation 1994; 90: 1520
    • (1994) Circulation , vol.90 , pp. 1520
    • Reid, C.L.1    Gardin, J.M.2    Yunis, C.3
  • 122
    • 0035060595 scopus 로고    scopus 로고
    • Appetite suppressants and valvular heart disease
    • Weissman NJ. Appetite suppressants and valvular heart disease. Am J Med Sci 2001; 321: 285-91
    • (2001) Am J Med Sci , vol.321 , pp. 285-291
    • Weissman, N.J.1
  • 123
    • 0031567756 scopus 로고    scopus 로고
    • Cardiac valvulopathy associated with exposure to fenfluramine or dexfenfluramine
    • US Department of Health and Human Services Interim Public Health Recommendations. November 1997
    • Bowen R, Glicklich A, Khan K, et al. Cardiac valvulopathy associated with exposure to fenfluramine or dexfenfluramine. US Department of Health and Human Services Interim Public Health Recommendations. November 1997. MMWR Morb Mortal Wkly Rep 1997; 46: 1061-6
    • (1997) MMWR Morb Mortal Wkly Rep , vol.46 , pp. 1061-1066
    • Bowen, R.1    Glicklich, A.2    Khan, K.3
  • 124
    • 0030739720 scopus 로고    scopus 로고
    • Further cases of valvular heart disease associated with fenfluramine-phentermine
    • Graham DJ, Green L. Further cases of valvular heart disease associated with fenfluramine-phentermine. N Engl J Med 1997; 337: 635
    • (1997) N Engl J Med , vol.337 , pp. 635
    • Graham, D.J.1    Green, L.2
  • 125
    • 0030853477 scopus 로고    scopus 로고
    • Valvular heart disease associated with dexfenfluramine
    • Cannistra LB, Davis SM, Bauman AG. Valvular heart disease associated with dexfenfluramine. N Engl J Med 1997; 337: 636
    • (1997) N Engl J Med , vol.337 , pp. 636
    • Cannistra, L.B.1    Davis, S.M.2    Bauman, A.G.3
  • 126
    • 0031915680 scopus 로고    scopus 로고
    • Asymptomatic mitral and aortic valve disease is seen in half of the patients taking 'Phen-Fen'
    • Griffen L, Anchors M. Asymptomatic mitral and aortic valve disease is seen in half of the patients taking 'Phen-Fen'. Arch Intern Med 1998; 158: 102
    • (1998) Arch Intern Med , vol.158 , pp. 102
    • Griffen, L.1    Anchors, M.2
  • 127
    • 0031565156 scopus 로고    scopus 로고
    • Valvular heart disease associated with fenfluramine-phentermine
    • Rasmussen S, Corya BC, Glassman RD. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med 1997; 337: 1772-6
    • (1997) N Engl J Med , vol.337 , pp. 1772-1776
    • Rasmussen, S.1    Corya, B.C.2    Glassman, R.D.3
  • 128
    • 0032504958 scopus 로고    scopus 로고
    • Regression of multivalvular regurgitation after the cessation of fenfluramine and phentermine treatment
    • Cannistra LB, Cannistra AJ. Regression of multivalvular regurgitation after the cessation of fenfluramine and phentermine treatment. N Engl J Med 1998; 339: 771
    • (1998) N Engl J Med , vol.339 , pp. 771
    • Cannistra, L.B.1    Cannistra, A.J.2
  • 129
    • 0032504948 scopus 로고    scopus 로고
    • The prevalence of cardiac valvular insufficiency assessed by transthoracic echocardiography in obese patients treated with appetite-suppressant drugs
    • Khan MA, Herzog CA, St Peter JV, et al. The prevalence of cardiac valvular insufficiency assessed by transthoracic echocardiography in obese patients treated with appetite-suppressant drugs. N Engl J Med 1998; 339: 713-8
    • (1998) N Engl J Med , vol.339 , pp. 713-718
    • Khan, M.A.1    Herzog, C.A.2    St Peter, J.V.3
  • 130
    • 0032505060 scopus 로고    scopus 로고
    • An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo
    • Sustained-release Dexfenfluramine Study Group
    • Weissman NJ, Tighe JF, Gottdiener JS, et al. An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo. Sustained-release Dexfenfluramine Study Group. N Engl J Med 1998; 339: 725-32
    • (1998) N Engl J Med , vol.339 , pp. 725-732
    • Weissman, N.J.1    Tighe, J.F.2    Gottdiener, J.S.3
  • 131
    • 0034595380 scopus 로고    scopus 로고
    • Fenfluramine and phentermine and cardiovascular findings: Effect of treatment duration on prevalence of valve abnormalities
    • Jollis JG, Landolfo CK, Kisslo J, et al. Fenfluramine and phentermine and cardiovascular findings: effect of treatment duration on prevalence of valve abnormalities. Circulation 2000; 101: 2071-7
    • (2000) Circulation , vol.101 , pp. 2071-2077
    • Jollis, J.G.1    Landolfo, C.K.2    Kisslo, J.3
  • 133
    • 22644439146 scopus 로고    scopus 로고
    • Framingham Heart Study
    • Singl JP, Evans J, Levy D, et al. Framingham Heart Study [abstract]. Circulation 1997; 96: 1541
    • (1997) Circulation , vol.96 , pp. 1541
    • Singl, J.P.1    Evans, J.2    Levy, D.3
  • 134
    • 0032113525 scopus 로고    scopus 로고
    • The fen-phen finale: A study of weight loss and valvular disease
    • Wadden TA, Berkowitz RI, Silvestry F, et al. The fen-phen finale: a study of weight loss and valvular disease. Obes Res 1998; 6: 278-84
    • (1998) Obes Res , vol.6 , pp. 278-284
    • Wadden, T.A.1    Berkowitz, R.I.2    Silvestry, F.3
  • 135
    • 0032404014 scopus 로고    scopus 로고
    • Risk for valvular heart disease among users of fenfluramine and dexfenfluramine who underwent echocardiography before use of medication
    • Wee CC, Phillips RS, Aurigemma G, et al. Risk for valvular heart disease among users of fenfluramine and dexfenfluramine who underwent echocardiography before use of medication. Ann Intern Med 1998; 129: 870-4
    • (1998) Ann Intern Med , vol.129 , pp. 870-874
    • Wee, C.C.1    Phillips, R.S.2    Aurigemma, G.3
  • 136
    • 0033162130 scopus 로고    scopus 로고
    • Serial echocardiographic and clinical evaluation of valvular regurgitation before, during and after treatment with fenfluramine or dexfenfluramine and mazindol or phentermine
    • Ryan DH, Bray GA, Helmcke F, et al. Serial echocardiographic and clinical evaluation of valvular regurgitation before, during and after treatment with fenfluramine or dexfenfluramine and mazindol or phentermine. Obes Res 1999; 7: 313-22
    • (1999) Obes Res , vol.7 , pp. 313-322
    • Ryan, D.H.1    Bray, G.A.2    Helmcke, F.3
  • 137
    • 0033213380 scopus 로고    scopus 로고
    • Low prevalence of valvular heart disease in 226 phentermine-fenfluramine protocol subjects prospectively followed for up to 30 months
    • Burger AJ, Sherman HB, Charlamb MJ, et al. Low prevalence of valvular heart disease in 226 phentermine-fenfluramine protocol subjects prospectively followed for up to 30 months. J Am Coll Cardiol 1999; 34: 1153-8
    • (1999) J Am Coll Cardiol , vol.34 , pp. 1153-1158
    • Burger, A.J.1    Sherman, H.B.2    Charlamb, M.J.3
  • 138
    • 0032747457 scopus 로고    scopus 로고
    • Echocardiographic prevalence of mitral and/or aortic regurgitation in patients exposed to either fenfluramine-phentermine combination or to dexfenfluramine
    • Kancherla MK, Salti HI, Mulderink TA, et al. Echocardiographic prevalence of mitral and/or aortic regurgitation in patients exposed to either fenfluramine-phentermine combination or to dexfenfluramine. Am J Cardiol 1999; 84: 1335-8
    • (1999) Am J Cardiol , vol.84 , pp. 1335-1338
    • Kancherla, M.K.1    Salti, H.I.2    Mulderink, T.A.3
  • 139
    • 0034237285 scopus 로고    scopus 로고
    • Dose and duration of fenfluramine-phentermine therapy impacts the risk of significant valvular heart disease
    • Lepor NE, Gross SB, Daley WL, et al. Dose and duration of fenfluramine-phentermine therapy impacts the risk of significant valvular heart disease. Am J Cardiol 2000; 86: 107-10
    • (2000) Am J Cardiol , vol.86 , pp. 107-110
    • Lepor, N.E.1    Gross, S.B.2    Daley, W.L.3
  • 140
    • 0034924924 scopus 로고    scopus 로고
    • Low risk of significant echocardiographic valvulopathy in patients treated with anorectic drugs
    • Burger AJ, Charlamb MJ, Singh S, et al. Low risk of significant echocardiographic valvulopathy in patients treated with anorectic drugs. Int J Cardiol 2001; 79: 159-65
    • (2001) Int J Cardiol , vol.79 , pp. 159-165
    • Burger, A.J.1    Charlamb, M.J.2    Singh, S.3
  • 141
    • 0033454750 scopus 로고    scopus 로고
    • Prevalence of valvular-regurgitation associated with dexfenfluramine three to five months after discontinuation of treatment
    • Weissman NJ, Tighe JF, Gottdiener JS, et al. Prevalence of valvular-regurgitation associated with dexfenfluramine three to five months after discontinuation of treatment. J Am Coll Cardiol 1999; 34: 2088-95
    • (1999) J Am Coll Cardiol , vol.34 , pp. 2088-2095
    • Weissman, N.J.1    Tighe, J.F.2    Gottdiener, J.S.3
  • 142
    • 0033598676 scopus 로고    scopus 로고
    • Prevalence and determinants of valvulopathy in patients treated with dexfenfluramine
    • Shively BK, Roldan CA, Gill EA, et al. Prevalence and determinants of valvulopathy in patients treated with dexfenfluramine. Circulation 1999; 100: 2161-7
    • (1999) Circulation , vol.100 , pp. 2161-2167
    • Shively, B.K.1    Roldan, C.A.2    Gill, E.A.3
  • 143
    • 0032738754 scopus 로고    scopus 로고
    • Echocardiographic improvement over time after cessation of use of fenfluramine and phentermine
    • Hensrud DD, Conolly HM, Grogan M, et al. Echocardiographic improvement over time after cessation of use of fenfluramine and phentermine. Mayo Clin Proc 1999; 74: 1191-7
    • (1999) Mayo Clin Proc , vol.74 , pp. 1191-1197
    • Hensrud, D.D.1    Conolly, H.M.2    Grogan, M.3
  • 144
    • 0034607394 scopus 로고    scopus 로고
    • Valvular abnormalities and cardiovascular status following exposure to dexfenfluramine or phentermine/fenfluramine
    • Gardin JM, Schumacher D, Constantine G, et al. Valvular abnormalities and cardiovascular status following exposure to dexfenfluramine or phentermine/fenfluramine. JAMA 2000; 283: 1703-9
    • (2000) JAMA , vol.283 , pp. 1703-1709
    • Gardin, J.M.1    Schumacher, D.2    Constantine, G.3
  • 145
    • 0034921587 scopus 로고    scopus 로고
    • Echocardiographic examination of women previously treated with fenfluramine. Long-term follow-up of a randomised, double blind, placebo-controlled trial
    • Davidoff R, McTiernan A, Constantine G, et al. Echocardiographic examination of women previously treated with fenfluramine. Long-term follow-up of a randomised, double blind, placebo-controlled trial. Arch Intern Med 2001; 161: 1429-36
    • (2001) Arch Intern Med , vol.161 , pp. 1429-1436
    • Davidoff, R.1    McTiernan, A.2    Constantine, G.3
  • 146
    • 0032504983 scopus 로고    scopus 로고
    • A population based study of appetite suppressant drugs and the risk of cardiac-valve regurgitation
    • Jick H, Vasilakis C, Weinrauch LA, et al. A population based study of appetite suppressant drugs and the risk of cardiac-valve regurgitation. N Engl J Med 1998; 339: 719-24
    • (1998) N Engl J Med , vol.339 , pp. 719-724
    • Jick, H.1    Vasilakis, C.2    Weinrauch, L.A.3
  • 147
    • 0025138156 scopus 로고
    • Age-related prevalence of valvular regurgitation in normal suibjects
    • Klein AL, Burstow DJ, Tajik AJ, et al. Age-related prevalence of valvular regurgitation in normal suibjects. J AM Soc Echocardiogr 1990; 3: 54-63
    • (1990) J AM Soc Echocardiogr , vol.3 , pp. 54-63
    • Klein, A.L.1    Burstow, D.J.2    Tajik, A.J.3
  • 148
    • 4243245869 scopus 로고
    • Age-related changes in cardiac function by color Doppler echocardiography
    • Shively B, Roldan C, Gurule F, et al. Age-related changes in cardiac function by color Doppler echocardiography. J AM Coll Cardiol 1990; 15: 187A
    • (1990) J AM Coll Cardiol , vol.15
    • Shively, B.1    Roldan, C.2    Gurule, F.3
  • 149
    • 0035916262 scopus 로고    scopus 로고
    • Natural history of valvular regurgitation 1 year after discontinuation of dexfenfluramine therapy: A randomised, double-blind, placebo-controlled trial
    • Weissman NJ, Panza JA, Tighe JF, et al. Natural history of valvular regurgitation 1 year after discontinuation of dexfenfluramine therapy: a randomised, double-blind, placebo-controlled trial. Ann Intern Med 2001; 134: 267-73
    • (2001) Ann Intern Med , vol.134 , pp. 267-273
    • Weissman, N.J.1    Panza, J.A.2    Tighe, J.F.3
  • 150
    • 0035944519 scopus 로고    scopus 로고
    • Clinical and echocardiographic follow-up of patients previously treated with dexfenfluramine or phentermine/fenfluramine
    • Gardin JM, Weissman NJ, Leung C, et al. Clinical and echocardiographic follow-up of patients previously treated with dexfenfluramine or phentermine/fenfluramine. JAMA 2001; 286: 2011-4
    • (2001) JAMA , vol.286 , pp. 2011-2014
    • Gardin, J.M.1    Weissman, N.J.2    Leung, C.3
  • 151
    • 0035916278 scopus 로고    scopus 로고
    • The progression of fenfluramine-associated valvular heart disease assessed by echocardiography
    • Mast ST, Jollis JG, Ryan T, et al. The progression of fenfluramine-associated valvular heart disease assessed by echocardiography. Ann Intern Med 2001; 134: 261-6
    • (2001) Ann Intern Med , vol.134 , pp. 261-266
    • Mast, S.T.1    Jollis, J.G.2    Ryan, T.3
  • 152
    • 0037133534 scopus 로고    scopus 로고
    • Regression and progression of valvulopathy associated with fenfluramine and phentermine
    • Dahl CF, Allen MR. Regression and progression of valvulopathy associated with fenfluramine and phentermine. Ann Intern Med 2002; 136: 489
    • (2002) Ann Intern Med , vol.136 , pp. 489
    • Dahl, C.F.1    Allen, M.R.2
  • 153
    • 0038702049 scopus 로고    scopus 로고
    • High prevalence of fenfluramine-related aortic regurgitation in women with end-stage renal disease secondary to Chinese herb nephropathy
    • Unger P, Nortier J, Martinez MM, et al. High prevalence of fenfluramine-related aortic regurgitation in women with end-stage renal disease secondary to Chinese herb nephropathy. Nephrol Dial Transpl 2003; 18: 906-10
    • (2003) Nephrol Dial Transpl , vol.18 , pp. 906-910
    • Unger, P.1    Nortier, J.2    Martinez, M.M.3
  • 154
    • 0032850030 scopus 로고    scopus 로고
    • Dose-effect of fenfluramine use on the severity of valvular heart disease among fen-phen patients with valvulopathy
    • Li R, Serdula MK, Williamson DF, et al. Dose-effect of fenfluramine use on the severity of valvular heart disease among fen-phen patients with valvulopathy. Int J Obes Relat Metab Disord 1999; 23: 926-8
    • (1999) Int J Obes Relat Metab Disord , vol.23 , pp. 926-928
    • Li, R.1    Serdula, M.K.2    Williamson, D.F.3
  • 155
    • 0032403033 scopus 로고    scopus 로고
    • Diet-drug debacle
    • Parisi AF. Diet-drug debacle. Ann Intern Med 1998; 129: 903-5
    • (1998) Ann Intern Med , vol.129 , pp. 903-905
    • Parisi, A.F.1
  • 156
    • 0036911037 scopus 로고    scopus 로고
    • Effect of fenfluramine-derivative diet pills on cardiac valves: A meta-analysis of observational studies
    • Sachdev M, Miller WC, Ryan T, et al. Effect of fenfluramine-derivative diet pills on cardiac valves: a meta-analysis of observational studies. Am Heart J 2002; 144: 1065-73
    • (2002) Am Heart J , vol.144 , pp. 1065-1073
    • Sachdev, M.1    Miller, W.C.2    Ryan, T.3
  • 157
    • 0003376125 scopus 로고    scopus 로고
    • Appetite suppressants and valvular heart disease: A systematic review [online]
    • Loke YK, Derry S, Pritchard-Copley A. Appetite suppressants and valvular heart disease: a systematic review [online]. BMC Clin Pharmacol 2002; 2: 6. Available from URL: www.biomedcentral.com/1472-6904/2/6 [Accessed 2003 Dec 1]
    • (2002) BMC Clin Pharmacol , vol.2 , pp. 6
    • Loke, Y.K.1    Derry, S.2    Pritchard-Copley, A.3
  • 158
    • 29044432087 scopus 로고    scopus 로고
    • Natural history of valvular regurgitation using side-by-side echocardiographic analysis in anorexigen-treated subjects
    • Klein AL, Griffin BP, Grimm RA, et al. Natural history of valvular regurgitation using side-by-side echocardiographic analysis in anorexigen-treated subjects. Am J Cardiol 2005; 96: 1711-7
    • (2005) Am J Cardiol , vol.96 , pp. 1711-1717
    • Klein, A.L.1    Griffin, B.P.2    Grimm, R.A.3
  • 159
    • 4243712036 scopus 로고    scopus 로고
    • Transesophageal echocardiography in phentermine-fenfluramine users suggests frequent misdiagnosis of valvular heart disease by transthoracic echocardiography
    • Roldan CA, Decker PJ, Gelgand EA, et al. Transesophageal echocardiography in phentermine-fenfluramine users suggests frequent misdiagnosis of valvular heart disease by transthoracic echocardiography [abstract]. J Am Coll Cardiol 1999; 33: 549A
    • (1999) J Am Coll Cardiol , vol.33
    • Roldan, C.A.1    Decker, P.J.2    Gelgand, E.A.3
  • 160
    • 0033179867 scopus 로고    scopus 로고
    • Detailed examination of fenfluramine-phentermine users with valve abnormalities identified in Fargo, North Dakota
    • Kimmel SE, Keane MG, Crary JL, et al. Detailed examination of fenfluramine-phentermine users with valve abnormalities identified in Fargo, North Dakota. Am J Cardiol 1999; 84: 304-8
    • (1999) Am J Cardiol , vol.84 , pp. 304-308
    • Kimmel, S.E.1    Keane, M.G.2    Crary, J.L.3
  • 161
    • 0033514006 scopus 로고    scopus 로고
    • Phentermine and other monoamine-oxidase inhibitors may increase plasma serotonin when given with fenfluramines
    • Maher TJ, Ulus IH, Wurtman RJ. Phentermine and other monoamine-oxidase inhibitors may increase plasma serotonin when given with fenfluramines. Lancet 1999; 353: 38
    • (1999) Lancet , vol.353 , pp. 38
    • Maher, T.J.1    Ulus, I.H.2    Wurtman, R.J.3
  • 162
    • 0642341479 scopus 로고    scopus 로고
    • Risk of valvular heart disease associated with use of fenfluramine [online]
    • Hopkins PN, Polukoff GI. Risk of valvular heart disease associated with use of fenfluramine [online]. BMC Cardiovasc Dis 2003; 3 (1): 5. Available from URL: www.biomedcentral.com/1471-226/3/5 [Accessed 2003 Dec 1]
    • (2003) BMC Cardiovasc Dis , vol.3 , Issue.1 , pp. 5
    • Hopkins, P.N.1    Polukoff, G.I.2
  • 163
    • 0016176562 scopus 로고
    • Cardiac murmurs and endocardial fibrosis associated with methysergide therapy
    • Bana DS, MacNeal PS, LeCompte PM, et al. Cardiac murmurs and endocardial fibrosis associated with methysergide therapy. Am Heart J 1974; 88: 640-55
    • (1974) Am Heart J , vol.88 , pp. 640-655
    • Bana, D.S.1    MacNeal, P.S.2    LeCompte, P.M.3
  • 164
    • 0026723484 scopus 로고
    • Valve disease associated with ergot alkaloid use: Echocardiographic and pathologic correlations
    • Redfield MM, Nicholson WJ, Edwards WD, et al. Valve disease associated with ergot alkaloid use: echocardiographic and pathologic correlations. Ann Intern Med 1992; 117: 50-2
    • (1992) Ann Intern Med , vol.117 , pp. 50-52
    • Redfield, M.M.1    Nicholson, W.J.2    Edwards, W.D.3
  • 165
    • 0025273121 scopus 로고
    • Mitral and aortic valve disease associated with ergotamine therapy for migraine. Report of two cases and review of literature
    • Hauck AJ, Edwards WD, Danielson GK, et al. Mitral and aortic valve disease associated with ergotamine therapy for migraine. Report of two cases and review of literature. Arch Pathol Lab Med 1990; 114: 62-4
    • (1990) Arch Pathol Lab Med , vol.114 , pp. 62-64
    • Hauck, A.J.1    Edwards, W.D.2    Danielson, G.K.3
  • 166
    • 0036894736 scopus 로고    scopus 로고
    • Valvular heart disease in patients taking pergolide
    • Pritchett AM, Morrison JF, Edwards WD, et al. Valvular heart disease in patients taking pergolide. Mayo Clin Proc 2002; 77: 1280-6
    • (2002) Mayo Clin Proc , vol.77 , pp. 1280-1286
    • Pritchett, A.M.1    Morrison, J.F.2    Edwards, W.D.3
  • 167
    • 4444351812 scopus 로고    scopus 로고
    • Severe multivalvular heart disease: A new complication of the ergot derivative dopamine agonists
    • Horvath J, Fross RD, Kleiner-Fisman G, et al. Severe multivalvular heart disease: a new complication of the ergot derivative dopamine agonists. Mov Disord 2004; 19: 656-62
    • (2004) Mov Disord , vol.19 , pp. 656-662
    • Horvath, J.1    Fross, R.D.2    Kleiner-Fisman, G.3
  • 168
    • 0034607330 scopus 로고    scopus 로고
    • Heart valve disorders and appetite-suppressant drugs
    • Jick H. Heart valve disorders and appetite-suppressant drugs. JAMA 2000; 283: 1738-40
    • (2000) JAMA , vol.283 , pp. 1738-1740
    • Jick, H.1
  • 169
    • 0032496607 scopus 로고    scopus 로고
    • The 'Phen-Pro' diet drug combination is not associated with valvular heart disease
    • Griffen L, Anchors M. The 'Phen-Pro' diet drug combination is not associated with valvular heart disease. Arch Intern Med 1998; 158: 1278-9
    • (1998) Arch Intern Med , vol.158 , pp. 1278-1279
    • Griffen, L.1    Anchors, M.2
  • 170
    • 0035871561 scopus 로고    scopus 로고
    • Association between selective serotonin-reuptake inhibitor therapy and heart valve regurgitation
    • Mast ST, Gersing KR, Anstrom KJ, et al. Association between selective serotonin-reuptake inhibitor therapy and heart valve regurgitation. Am J Cardiol 2001; 87: 989-93
    • (2001) Am J Cardiol , vol.87 , pp. 989-993
    • Mast, S.T.1    Gersing, K.R.2    Anstrom, K.J.3
  • 171
    • 0036562231 scopus 로고    scopus 로고
    • Evaluation of efficacy, reliability, and tolerability of sibutramine in obese patients with an echocardiographic study
    • Halpern A, Leite CC, Herszkowicz N, et al. Evaluation of efficacy, reliability, and tolerability of sibutramine in obese patients with an echocardiographic study. Rev Hosp Clin Fac Med Sao Paulo 2002; 57: 98-102
    • (2002) Rev Hosp Clin Fac Med Sao Paulo , vol.57 , pp. 98-102
    • Halpern, A.1    Leite, C.C.2    Herszkowicz, N.3
  • 172
    • 0036733520 scopus 로고    scopus 로고
    • Effects of sibutramine on ventricular dimensions and heart valves in obese patients during weight reduction
    • Zannad F, Gille B, Grentzinger A, et al. Effects of sibutramine on ventricular dimensions and heart valves in obese patients during weight reduction. Am Heart J 2002; 144: 508-15
    • (2002) Am Heart J , vol.144 , pp. 508-515
    • Zannad, F.1    Gille, B.2    Grentzinger, A.3
  • 173
    • 0033160668 scopus 로고    scopus 로고
    • Absence of cardiac valve dysfunction in obese patients treated with sibutramine
    • Bach DS, Rissanen AM, Mendel CM, et al. Absence of cardiac valve dysfunction in obese patients treated with sibutramine. Obes Res 1999; 7: 363-9
    • (1999) Obes Res , vol.7 , pp. 363-369
    • Bach, D.S.1    Rissanen, A.M.2    Mendel, C.M.3
  • 174
    • 18844471683 scopus 로고    scopus 로고
    • Endocardial fibrosis associated with fenfluramine-phentermine
    • Fowles RE, Cloward TV, Yowell RL. Endocardial fibrosis associated with fenfluramine-phentermine. N Engl J Med 1998; 338: 1316
    • (1998) N Engl J Med , vol.338 , pp. 1316
    • Fowles, R.E.1    Cloward, T.V.2    Yowell, R.L.3
  • 175
    • 0031032217 scopus 로고    scopus 로고
    • Appetite-suppressant drugs and pulmonary hypertension
    • Schembre DB, Boynton KK. Appetite-suppressant drugs and pulmonary hypertension [letter]. N Engl J Med 1997; 336: 510-1
    • (1997) N Engl J Med , vol.336 , pp. 510-511
    • Schembre, D.B.1    Boynton, K.K.2
  • 176
    • 0030864903 scopus 로고    scopus 로고
    • Cerebral haemorrhage in patient taking fenfluramine and phentermine for obesity
    • Wen PY, Feske SK, Teoh SK, et al. Cerebral haemorrhage in patient taking fenfluramine and phentermine for obesity. Neurology 1997; 49: 632-3
    • (1997) Neurology , vol.49 , pp. 632-633
    • Wen, P.Y.1    Feske, S.K.2    Teoh, S.K.3
  • 177
    • 0021810360 scopus 로고
    • Therapeutic doses of phenylpropanolamine increase supine systolic blood pressure
    • Pentel PR, Aaron C, Paya C. Therapeutic doses of phenylpropanolamine increase supine systolic blood pressure. Int J Obes 1985; 9: 115-9
    • (1985) Int J Obes , vol.9 , pp. 115-119
    • Pentel, P.R.1    Aaron, C.2    Paya, C.3
  • 178
    • 0025105618 scopus 로고
    • Adverse drug effects attributed to phenylpropanolamine: A review of 142 case reports
    • Lake CR, Gallant S, Masson E, et al. Adverse drug effects attributed to phenylpropanolamine: a review of 142 case reports. Am J Med 1990; 89: 195-208
    • (1990) Am J Med , vol.89 , pp. 195-208
    • Lake, C.R.1    Gallant, S.2    Masson, E.3
  • 179
    • 0029794323 scopus 로고    scopus 로고
    • Phenylpropanolamine and associated myocardial injury
    • Leo PJ, Hollander JE, Shih RD, et al. Phenylpropanolamine and associated myocardial injury. Ann Emerg Med 1996; 28: 359-62
    • (1996) Ann Emerg Med , vol.28 , pp. 359-362
    • Leo, P.J.1    Hollander, J.E.2    Shih, R.D.3
  • 180
    • 0037730236 scopus 로고    scopus 로고
    • Case report: Dexatrim (Phenylpropanolamine) as a cause of myocardial infarction
    • Pilsczek FH, Karcic AA, Freeman I. Case report: Dexatrim (Phenylpropanolamine) as a cause of myocardial infarction. Heart Lung 2003; 32: 100-4
    • (2003) Heart Lung , vol.32 , pp. 100-104
    • Pilsczek, F.H.1    Karcic, A.A.2    Freeman, I.3
  • 181
    • 0027476310 scopus 로고
    • Possible association of ischemic stroke with phentermine
    • Kokkinos J, Levine SR. Possible association of ischemic stroke with phentermine. Stroke 1993; 24: 310-3
    • (1993) Stroke , vol.24 , pp. 310-313
    • Kokkinos, J.1    Levine, S.R.2
  • 182
    • 0027749194 scopus 로고
    • Transient ischemic attacks associated with amfepramone therapy: A case report
    • Crols R, Dierckx R, Saerens J, et al. Transient ischemic attacks associated with amfepramone therapy: a case report. Functional Neurol 1993; 8: 351-4
    • (1993) Functional Neurol , vol.8 , pp. 351-354
    • Crols, R.1    Dierckx, R.2    Saerens, J.3
  • 183
    • 0032111931 scopus 로고    scopus 로고
    • A comparison of sibutramine and dexfenfluramine in the treatment of obesity
    • Hanotin C, Thomas F, Jones SP, et al. A comparison of sibutramine and dexfenfluramine in the treatment of obesity. Obes Res 1998; 6: 285-91
    • (1998) Obes Res , vol.6 , pp. 285-291
    • Hanotin, C.1    Thomas, F.2    Jones, S.P.3
  • 184
    • 85047697192 scopus 로고    scopus 로고
    • Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors
    • McMahon FG, Weinstein SP, Rowe E, et al. Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors. J Hum Hypertens 2002; 16: 5-11
    • (2002) J Hum Hypertens , vol.16 , pp. 5-11
    • McMahon, F.G.1    Weinstein, S.P.2    Rowe, E.3
  • 185
    • 0037027498 scopus 로고    scopus 로고
    • Paradoxical effect of sibutramine on autonomic cardiovascular regulation
    • Birkenfeld AL, Schroeder C, Boschmann M, et al. Paradoxical effect of sibutramine on autonomic cardiovascular regulation. Circulation 2002; 106: 2459-65
    • (2002) Circulation , vol.106 , pp. 2459-2465
    • Birkenfeld, A.L.1    Schroeder, C.2    Boschmann, M.3
  • 186
    • 0035925923 scopus 로고    scopus 로고
    • Drug therapy for management of obesity
    • Heine RJ. Drug therapy for management of obesity [letter]. Lancet 2001; 357: 1287
    • (2001) Lancet , vol.357 , pp. 1287
    • Heine, R.J.1
  • 187
    • 14944383697 scopus 로고    scopus 로고
    • Sibutramine: Possible cause of a reversible cardiomyopathy
    • Sayin T, Güldal M. Sibutramine: possible cause of a reversible cardiomyopathy [letter]. Int J Cardiol 2005; 99: 481-2
    • (2005) Int J Cardiol , vol.99 , pp. 481-482
    • Sayin, T.1    Güldal, M.2
  • 188
    • 17444409332 scopus 로고    scopus 로고
    • Effects of sibutramine on abdominal fat mass, insulin resistance and blood pressure in obese hypertensive patients
    • Faria AN, Ribeiro Filho FF, Kohlmann NE, et al. Effects of sibutramine on abdominal fat mass, insulin resistance and blood pressure in obese hypertensive patients. Diabetes Obes Metab 2005; 7: 246-53
    • (2005) Diabetes Obes Metab , vol.7 , pp. 246-253
    • Faria, A.N.1    Ribeiro Filho, F.F.2    Kohlmann, N.E.3
  • 189
    • 0023184319 scopus 로고
    • Phenylpropanolamine: An over-the-counter drug causing central nervous system vasculitis and intracerebral hemorrhage: case report and review
    • Glick R, Hoying J, Cerullo L, et al. Phenylpropanolamine: an over-the-counter drug causing central nervous system vasculitis and intracerebral hemorrhage: case report and review. Neurosurgery 1987; 20: 969-74
    • (1987) Neurosurgery , vol.20 , pp. 969-974
    • Glick, R.1    Hoying, J.2    Cerullo, L.3
  • 190
    • 0023155462 scopus 로고
    • Intracerebral hemorrhage and phenylpropanolamine use
    • Kase CS, Foster TE, Reed JE, et al. Intracerebral hemorrhage and phenylpropanolamine use. Neurology 1987; 37: 399-404
    • (1987) Neurology , vol.37 , pp. 399-404
    • Kase, C.S.1    Foster, T.E.2    Reed, J.E.3
  • 191
    • 0021320948 scopus 로고
    • Cerebral hemorrhage associated with phenylpropanolamine in combination with caffeine
    • Mueller SM, Muller J, Asdell SM. Cerebral hemorrhage associated with phenylpropanolamine in combination with caffeine. Stroke 1984; 15: 119-23
    • (1984) Stroke , vol.15 , pp. 119-123
    • Mueller, S.M.1    Muller, J.2    Asdell, S.M.3
  • 193
    • 0034700436 scopus 로고    scopus 로고
    • Phenylpropanolamine and risk of hemorrhagic stroke
    • Kernan WN, Viscoli CM, Brass LM, et al. Phenylpropanolamine and risk of hemorrhagic stroke. N Engl J Med 2000; 343: 1826-32
    • (2000) N Engl J Med , vol.343 , pp. 1826-1832
    • Kernan, W.N.1    Viscoli, C.M.2    Brass, L.M.3
  • 194
    • 0030867864 scopus 로고    scopus 로고
    • Brain serotonin neurotoxicity and primary pulmonary hypertension from fenfluramine and dexfenfluramine: A systematic review of the evidence
    • McCann UD, Seiden LS, Rubin LJ, et al. Brain serotonin neurotoxicity and primary pulmonary hypertension from fenfluramine and dexfenfluramine: a systematic review of the evidence. JAMA 1997; 278: 666-72
    • (1997) JAMA , vol.278 , pp. 666-672
    • McCann, U.D.1    Seiden, L.S.2    Rubin, L.J.3
  • 195
    • 0016134806 scopus 로고
    • Amphetamine psychosis: Behavioral and biochemical aspects
    • Angrist B, Sathananthan G, Wilk S, et al. Amphetamine psychosis: behavioral and biochemical aspects. J Psychiatr Res 1974; 11: 13-23
    • (1974) J Psychiatr Res , vol.11 , pp. 13-23
    • Angrist, B.1    Sathananthan, G.2    Wilk, S.3
  • 196
    • 0016874816 scopus 로고
    • Biochemistry and behavior: Some central actions of amphetamine and antipsychotic drugs
    • Groves PM, Rebec GV. Biochemistry and behavior: some central actions of amphetamine and antipsychotic drugs. Annu Rev Psychol 1976; 27: 91-127
    • (1976) Annu Rev Psychol , vol.27 , pp. 91-127
    • Groves, P.M.1    Rebec, G.V.2
  • 197
    • 0018718842 scopus 로고
    • Amphetamine psychosis and psychotic symptoms
    • Berl
    • Janowsky DS, Risch C. Amphetamine psychosis and psychotic symptoms. Psychopharmacology (Berl) 1979; 65: 73-7
    • (1979) Psychopharmacology , vol.65 , pp. 73-77
    • Janowsky, D.S.1    Risch, C.2
  • 198
    • 0033663511 scopus 로고    scopus 로고
    • Sibutramine-associated psychotic episode
    • Taflinski T, Chojnacka J. Sibutramine-associated psychotic episode [letter]. Am J Psychiatry 2000; 157: 2057-8
    • (2000) Am J Psychiatry , vol.157 , pp. 2057-2058
    • Taflinski, T.1    Chojnacka, J.2
  • 199
    • 14944365566 scopus 로고    scopus 로고
    • Sibutramine may be associated with memory impairment
    • Clark DWJ, Harrison-Woolrych M. Sibutramine may be associated with memory impairment. BMJ 2004; 329: 1316
    • (2004) BMJ , vol.329 , pp. 1316
    • Clark, D.W.J.1    Harrison-Woolrych, M.2
  • 200
    • 0042134607 scopus 로고    scopus 로고
    • Severe bullous drug eruption due to sibutramine (Reductil.)
    • Goh BK, Ng PP, Giam YC. Severe bullous drug eruption due to sibutramine (Reductil.). Br J Dermatol 2003; 149: 193-227
    • (2003) Br J Dermatol , vol.149 , pp. 193-227
    • Goh, B.K.1    Ng, P.P.2    Giam, Y.C.3
  • 201
    • 10844263352 scopus 로고    scopus 로고
    • Orlistat: A review of its use in the management of patients with obesity
    • Curran MP, Scott LJ. Orlistat: a review of its use in the management of patients with obesity. Drugs 2004; 64: 2845-64
    • (2004) Drugs , vol.64 , pp. 2845-2864
    • Curran, M.P.1    Scott, L.J.2
  • 202
    • 0031904104 scopus 로고    scopus 로고
    • Role of orlistat in the treatment of obese patients with type 2 diabetes
    • Hollander PA, Elbein SC, Hirsch IB, et al. Role of orlistat in the treatment of obese patients with type 2 diabetes. Diabetes Care 1998; 21: 1288-94
    • (1998) Diabetes Care , vol.21 , pp. 1288-1294
    • Hollander, P.A.1    Elbein, S.C.2    Hirsch, I.B.3
  • 203
    • 0034095342 scopus 로고    scopus 로고
    • One-year treatment of obesity: A randomized, double-blind, placebo-controlled, multicentre study of orlistat, a gastrointestinal lipase inhibitor
    • Finer N, James WP, Kopelman PG, et al. One-year treatment of obesity: a randomized, double-blind, placebo-controlled, multicentre study of orlistat, a gastrointestinal lipase inhibitor. Int J Obes Relat Metab Disord 2000; 24: 306-13
    • (2000) Int J Obes Relat Metab Disord , vol.24 , pp. 306-313
    • Finer, N.1    James, W.P.2    Kopelman, P.G.3
  • 204
    • 0030908378 scopus 로고    scopus 로고
    • A one-year trial to assess the value of orlistat in the management of obesity
    • James WPT, Avenell A, Broom J, et al. A one-year trial to assess the value of orlistat in the management of obesity. Int J Obes 1997; 21 Suppl. 3: 24-30
    • (1997) Int J Obes , vol.21 , Issue.3 SUPPL. , pp. 24-30
    • James, W.P.T.1    Avenell, A.2    Broom, J.3
  • 205
    • 0033829586 scopus 로고    scopus 로고
    • Orlistat in the long-term treatment of obesity in primary care settings, for the Orlistat Primary Care Study Group
    • Hauptman J, Lucas C, Boldrin MN, et al. Orlistat in the long-term treatment of obesity in primary care settings, for the Orlistat Primary Care Study Group. Arch Fam Med 2000; 9: 160-7
    • (2000) Arch Fam Med , vol.9 , pp. 160-167
    • Hauptman, J.1    Lucas, C.2    Boldrin, M.N.3
  • 206
    • 0029784311 scopus 로고    scopus 로고
    • The effect of orlistat, an inhibitor of dietary fat absorption, on the absorption of vitamins A and E in healthy volunteers
    • Melia AT, Koss-Twardy SG, Zhi J. The effect of orlistat, an inhibitor of dietary fat absorption, on the absorption of vitamins A and E in healthy volunteers. J Clin Pharmacol 1996; 36: 647-53
    • (1996) J Clin Pharmacol , vol.36 , pp. 647-653
    • Melia, A.T.1    Koss-Twardy, S.G.2    Zhi, J.3
  • 207
    • 0034264256 scopus 로고    scopus 로고
    • Effects of sibutramine plus orlistat in obese women following 1 year of treatment by sibutramine alone: A placebo-controlled trial
    • Wadden TA, Berkowitz RI, Womble LG, et al. Effects of sibutramine plus orlistat in obese women following 1 year of treatment by sibutramine alone: a placebo-controlled trial. Obes Res 2000; 6: 431-7
    • (2000) Obes Res , vol.6 , pp. 431-437
    • Wadden, T.A.1    Berkowitz, R.I.2    Womble, L.G.3
  • 208
    • 0034622162 scopus 로고    scopus 로고
    • Orlistat associated with hypertension
    • Persson M, Vitols S. Orlistat associated with hypertension. BMJ 2000; 321: 87
    • (2000) BMJ , vol.321 , pp. 87
    • Persson, M.1    Vitols, S.2
  • 209
    • 0034759572 scopus 로고    scopus 로고
    • Interaction between orlistat and antihypertensive drugs
    • Valsecia ME, Malgor LA, Farias EF, et al. Interaction between orlistat and antihypertensive drugs [letter]. Ann Pharmacother 2001; 35: 1495-6
    • (2001) Ann Pharmacother , vol.35 , pp. 1495-1496
    • Valsecia, M.E.1    Malgor, L.A.2    Farias, E.F.3
  • 210
    • 0032943963 scopus 로고    scopus 로고
    • Ruptured retroperitoneal aneurysm in a patient taking phentermine hydrochloride
    • Sobel RM. Ruptured retroperitoneal aneurysm in a patient taking phentermine hydrochloride. Am J Emerg Med 1999; 17: 102-3
    • (1999) Am J Emerg Med , vol.17 , pp. 102-103
    • Sobel, R.M.1
  • 211
    • 0346025612 scopus 로고    scopus 로고
    • Ischaemic colitis after weight loss medication
    • Comay D, Ramsay J, Irvine EJ. Ischaemic colitis after weight loss medication. Can J Gastroenterol 2003; 17: 719-21
    • (2003) Can J Gastroenterol , vol.17 , pp. 719-721
    • Comay, D.1    Ramsay, J.2    Irvine, E.J.3
  • 212
    • 0031669898 scopus 로고    scopus 로고
    • Acute interstital nephritis following treatment with anoretic agents phentermine and phendimetrazine
    • Markowitz GS, Tartini A, D'Agati VD. Acute interstital nephritis following treatment with anoretic agents phentermine and phendimetrazine. Clin Nephrol 1998; 50: 252-4
    • (1998) Clin Nephrol , vol.50 , pp. 252-254
    • Markowitz, G.S.1    Tartini, A.2    D'Agati, V.D.3
  • 213
    • 28044448496 scopus 로고    scopus 로고
    • Sibutramine use associated with reversible hepatotoxicity
    • Chounta A, Tsiodras S, Zouridakis S, et al. Sibutramine use associated with reversible hepatotoxicity. Annals Intern Med 2005; 143: 763-4
    • (2005) Annals Intern Med , vol.143 , pp. 763-764
    • Chounta, A.1    Tsiodras, S.2    Zouridakis, S.3
  • 214
    • 0034658466 scopus 로고    scopus 로고
    • Content versus label claims in ephedra-containing dietary supplements
    • Gurley BJ, Gardner SF, Hubbard MA. Content versus label claims in ephedra-containing dietary supplements. Am J Health Syst Pharm 2000; 57: 963-9
    • (2000) Am J Health Syst Pharm , vol.57 , pp. 963-969
    • Gurley, B.J.1    Gardner, S.F.2    Hubbard, M.A.3
  • 215
    • 0346219385 scopus 로고    scopus 로고
    • Ischemic stroke after using over the counter products containing ephedra
    • Chen C, Biller J, Willing SJ, et al. Ischemic stroke after using over the counter products containing ephedra. J Neurol Sci 2004; 217: 55-60
    • (2004) J Neurol Sci , vol.217 , pp. 55-60
    • Chen, C.1    Biller, J.2    Willing, S.J.3
  • 216
    • 0036261335 scopus 로고    scopus 로고
    • Herbal ephedra/caffeine for weight loss: A 6-month randomized safety and efficacy trial
    • Boozer CN, Daly PA, Homel P, et al. Herbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trial. Int J Obes 2002; 26: 593-604
    • (2002) Int J Obes , vol.26 , pp. 593-604
    • Boozer, C.N.1    Daly, P.A.2    Homel, P.3
  • 217
    • 0027301164 scopus 로고
    • Stroke associated with ephedrine use
    • Bruno A, Nolte KB, Chapin J. Stroke associated with ephedrine use. Neurol 1993; 43: 1313-6
    • (1993) Neurol , vol.43 , pp. 1313-1316
    • Bruno, A.1    Nolte, K.B.2    Chapin, J.3
  • 218
    • 0037435503 scopus 로고    scopus 로고
    • Use of Ephedra-containing products and risk for hemorrhagic stroke
    • Morgenstern LB, Viscoli CM, Kernan WN, et al. Use of Ephedra-containing products and risk for hemorrhagic stroke. Neurol 2003; 60: 132-5
    • (2003) Neurol , vol.60 , pp. 132-135
    • Morgenstern, L.B.1    Viscoli, C.M.2    Kernan, W.N.3
  • 219
    • 0345831912 scopus 로고    scopus 로고
    • Electrocardiographic and hemodynamic effects of a multicomponent dietary supplement containing ephedra and caffeine: A randomized controlled trial
    • McBride BF, Karapanos AK, Krudysz A, et al. Electrocardiographic and hemodynamic effects of a multicomponent dietary supplement containing ephedra and caffeine: a randomized controlled trial. JAMA 2004; 291: 216-21
    • (2004) JAMA , vol.291 , pp. 216-221
    • McBride, B.F.1    Karapanos, A.K.2    Krudysz, A.3
  • 221
    • 14844312121 scopus 로고    scopus 로고
    • Transient ischaemic attack associated with Metabolite 356 use
    • LoVecchio F, Eckholdt PA. Transient ischaemic attack associated with Metabolite 356 use. Am J Emerg Med 2005; 23: 199-200
    • (2005) Am J Emerg Med , vol.23 , pp. 199-200
    • LoVecchio, F.1    Eckholdt, P.A.2
  • 222
    • 9144260519 scopus 로고    scopus 로고
    • Three cases of liver injury caused by Sennomotokounou, a Chinese dietary supplement for weight loss
    • Kawata K, Takehira Y, Kobayashi Y, et al. Three cases of liver injury caused by Sennomotokounou, a Chinese dietary supplement for weight loss. Intern Med 2003; 42: 1188-92
    • (2003) Intern Med , vol.42 , pp. 1188-1192
    • Kawata, K.1    Takehira, Y.2    Kobayashi, Y.3
  • 223
    • 1642535488 scopus 로고    scopus 로고
    • Hepatic injury in 12 patients taking the herbal weight loss AIDS Chaso or Onshido
    • Adachi M, Saito H, Kobayashi H, et al. Hepatic injury in 12 patients taking the herbal weight loss AIDS Chaso or Onshido. Ann Intern Med 2003; 139: 488-92
    • (2003) Ann Intern Med , vol.139 , pp. 488-492
    • Adachi, M.1    Saito, H.2    Kobayashi, H.3
  • 224
    • 14844341365 scopus 로고    scopus 로고
    • Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut
    • Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005; 142: 477-8
    • (2005) Ann Intern Med , vol.142 , pp. 477-478
    • Stevens, T.1    Qadri, A.2    Zein, N.N.3
  • 225
    • 0037117466 scopus 로고    scopus 로고
    • Severe hepatotoxicity associated with the dietary supplement LipoKinetix
    • Favreau JT, Ryu ML, Braunstein G, et al. Severe hepatotoxicity associated with the dietary supplement LipoKinetix. Ann Intern Med 2002; 136: 590-5
    • (2002) Ann Intern Med , vol.136 , pp. 590-595
    • Favreau, J.T.1    Ryu, M.L.2    Braunstein, G.3
  • 226
    • 3442876096 scopus 로고    scopus 로고
    • Exercise-induced syncope associated with QT prolongation and ephedrine-free xenadrine
    • Nasir JM, Durning SJ, Ferguson M, et al. Exercise-induced syncope associated with QT prolongation and ephedrine-free xenadrine. Mayo Clin Proc 2004; 79: 1059-62
    • (2004) Mayo Clin Proc , vol.79 , pp. 1059-1062
    • Nasir, J.M.1    Durning, S.J.2    Ferguson, M.3
  • 227
    • 2942662323 scopus 로고    scopus 로고
    • Rhabdomyolysis in response to weight-loss herbal medicine
    • Mansi IA, Huang J. Rhabdomyolysis in response to weight-loss herbal medicine. Am J Med Sci 2004; 327: 356-7
    • (2004) Am J Med Sci , vol.327 , pp. 356-357
    • Mansi, I.A.1    Huang, J.2
  • 228
    • 0034622082 scopus 로고    scopus 로고
    • Urothelial carcinoma associated with the use of a Chinese herb (Aristochia fanchi)
    • Nortier JL, Martinez MC, Schmeiser HH, et al. Urothelial carcinoma associated with the use of a Chinese herb (Aristochia fanchi). N Engl J Med 2000; 342: 1686-92
    • (2000) N Engl J Med , vol.342 , pp. 1686-1692
    • Nortier, J.L.1    Martinez, M.C.2    Schmeiser, H.H.3
  • 229
    • 0037210410 scopus 로고    scopus 로고
    • Detection of aristolochic acid in Chinese phytomedicines and dietary supplements used as slimming regimens
    • Ioset J-R, Raoelison GE, Hostettmann K. Detection of aristolochic acid in Chinese phytomedicines and dietary supplements used as slimming regimens. Food Chem Toxicol 2003; 41: 29-36
    • (2003) Food Chem Toxicol , vol.41 , pp. 29-36
    • Ioset, J.-R.1    Raoelison, G.E.2    Hostettmann, K.3
  • 230
    • 0037229943 scopus 로고    scopus 로고
    • Aristochic acid and 'Chinese herbs nephropathy': A review of the evidence to date
    • Cosyns JP. Aristochic acid and 'Chinese herbs nephropathy': a review of the evidence to date. Drug Saf 2003; 26: 33-48
    • (2003) Drug Saf , vol.26 , pp. 33-48
    • Cosyns, J.P.1
  • 231
    • 0346593400 scopus 로고    scopus 로고
    • A 6-month randomized, placebo-controlled dose-ranging trial of topiramate for weight loss in obesity
    • Bray GA, Hollander P, Klein S, et al. A 6-month randomized, placebo-controlled dose-ranging trial of topiramate for weight loss in obesity. Obes Res 2003; 11: 722-33
    • (2003) Obes Res , vol.11 , pp. 722-733
    • Bray, G.A.1    Hollander, P.2    Klein, S.3
  • 232
    • 8344272013 scopus 로고    scopus 로고
    • A randomized double-blind placebo-controlled study of the long-term efficacy and safety of topiramate in the treatment of obese subjects
    • Wilding J, Van Gaal L, Rissanen A, et al. A randomized double-blind placebo-controlled study of the long-term efficacy and safety of topiramate in the treatment of obese subjects. Int J Obes 2004; 28: 1399-410
    • (2004) Int J Obes , vol.28 , pp. 1399-1410
    • Wilding, J.1    Van Gaal, L.2    Rissanen, A.3
  • 233
    • 16644400954 scopus 로고    scopus 로고
    • Topiramate: Long-term maintenance of weight loss induced by a low-calorie diet in obese subjects
    • Astrup A, Caterson I, Zelissen P, et al. Topiramate: long-term maintenance of weight loss induced by a low-calorie diet in obese subjects. Obes Res 2004; 12: 1658-69
    • (2004) Obes Res , vol.12 , pp. 1658-1669
    • Astrup, A.1    Caterson, I.2    Zelissen, P.3
  • 234
    • 15544384618 scopus 로고    scopus 로고
    • Topiramate: A new potential pharmacological treatment for obesity
    • Astrup A, Toubro S. Topiramate: a new potential pharmacological treatment for obesity. Obes Res 2004; 12 Suppl.: 167S-73S
    • (2004) Obes Res , vol.12 , Issue.SUPPL.
    • Astrup, A.1    Toubro, S.2
  • 235
    • 22144479432 scopus 로고    scopus 로고
    • Efficacy and safety of topiramate in the treatment of obese subjects with essential hypertension
    • Tonstad S, Tykarski A, Weissgarten J, et al. Efficacy and safety of topiramate in the treatment of obese subjects with essential hypertension. Am J Cardiol 2005; 96: 243-51
    • (2005) Am J Cardiol , vol.96 , pp. 243-251
    • Tonstad, S.1    Tykarski, A.2    Weissgarten, J.3
  • 236
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patient: 1-year experience from the RIO-Europe study
    • Van Gaal LF, Rissanen AM, Scheen AJ, et al. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patient: 1-year experience from the RIO-Europe study. Lancet 2005; 365: 1389-97
    • (2005) Lancet , vol.365 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3
  • 237
    • 32644441249 scopus 로고    scopus 로고
    • Effect of rimonabant a cannabinoid-1 receptor blocker on weight and cardiometabolic risk factors in overweight or obese patients. RIO-North America: A randomized controlled trial
    • Pi-Sunyer FX, Aronne LJ, Heshmati HM, et al for the RIO-North America Study Group. Effect of rimonabant a cannabinoid-1 receptor blocker on weight and cardiometabolic risk factors in overweight or obese patients. RIO-North America: a randomized controlled trial. JAMA 2006; 295: 761-75
    • (2006) JAMA , vol.295 , pp. 761-775
    • Pi-Sunyer, F.X.1    Aronne, L.J.2    Heshmati, H.M.3
  • 238
    • 30044448658 scopus 로고    scopus 로고
    • Rimonabant adds appetizing choice to slim obesity market
    • Wadman M. Rimonabant adds appetizing choice to slim obesity market. Nat Med 2006; 12 (1): 27
    • (2006) Nat Med , vol.12 , Issue.1 , pp. 27
    • Wadman, M.1
  • 239
    • 0037687348 scopus 로고    scopus 로고
    • Recombinant variant of ciliary neurotrophic factor for weight loss in obese adults: A randomized dose-ranging study
    • Ettinger MP, Littlejohn TW, Schwartz SL, et al. Recombinant variant of ciliary neurotrophic factor for weight loss in obese adults: a randomized dose-ranging study. JAMA 2003; 289: 1826-32
    • (2003) JAMA , vol.289 , pp. 1826-1832
    • Ettinger, M.P.1    Littlejohn, T.W.2    Schwartz, S.L.3
  • 240
    • 7944233492 scopus 로고    scopus 로고
    • Prescription weight loss pill use among Americans: Patterns of pill use and lessons learned from the fen-phen market withdrawal
    • Blanck HM, Khan LK, Serdula MK. Prescription weight loss pill use among Americans: patterns of pill use and lessons learned from the fen-phen market withdrawal. Prev Med 2004; 39: 1243-8
    • (2004) Prev Med , vol.39 , pp. 1243-1248
    • Blanck, H.M.1    Khan, L.K.2    Serdula, M.K.3
  • 241
    • 0037840394 scopus 로고    scopus 로고
    • Behavior therapy and sibutramine for the treatment of adolescent obesity: A randomized controlled trial
    • Berkowitz RI, Wadden TA, Tershakovec AM, et al. Behavior therapy and sibutramine for the treatment of adolescent obesity: a randomized controlled trial. JAMA 2003; 289: 1805-12
    • (2003) JAMA , vol.289 , pp. 1805-1812
    • Berkowitz, R.I.1    Wadden, T.A.2    Tershakovec, A.M.3
  • 242
    • 0036633087 scopus 로고    scopus 로고
    • Three-month tolerability of orlistat in adolescents with obesity-related comorbid conditions
    • McDuffie JR, Calis KA, Uwaifo GI, et al. Three-month tolerability of orlistat in adolescents with obesity-related comorbid conditions. Obes Res 2002; 10: 642-50
    • (2002) Obes Res , vol.10 , pp. 642-650
    • McDuffie, J.R.1    Calis, K.A.2    Uwaifo, G.I.3
  • 243
    • 20144389757 scopus 로고    scopus 로고
    • Treatment of obese adolescents with sibutramine: A randomised double-blind controlled study
    • Godoy-Matos A, Carraro L, Vieira A, et al. Treatment of obese adolescents with sibutramine: a randomised double-blind controlled study. J Clin Endocrinol Metab 2005; 90: 1460-5
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1460-1465
    • Godoy-Matos, A.1    Carraro, L.2    Vieira, A.3
  • 244
    • 20444446770 scopus 로고    scopus 로고
    • Effect of orlistat on weight and body composition in obese adolescents: A randomized controlled trial
    • Chanoine J-P, Hampl S, Jensen C, et al. Effect of orlistat on weight and body composition in obese adolescents: a randomized controlled trial. JAMA 2005; 293: 2873-83
    • (2005) JAMA , vol.293 , pp. 2873-2883
    • Chanoine, J.-P.1    Hampl, S.2    Jensen, C.3


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