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Volumn 37, Issue 11, 2014, Pages 693-699

Modern obesity pharmacotherapy: Weighing cardiovascular risk and benefit

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE PLUS NALTREXONE; LORCASERIN; PHENTERMINE PLUS TOPIRAMATE; SIBUTRAMINE; AMFEBUTAMONE; ANTIOBESITY AGENT; BENZAZEPINE DERIVATIVE; DRUG COMBINATION; FRUCTOSE; NALTREXONE; PHENTERMINE; TOPIRAMATE;

EID: 84913614397     PISSN: 01609289     EISSN: 19328737     Source Type: Journal    
DOI: 10.1002/clc.22304     Document Type: Review
Times cited : (32)

References (58)
  • 1
    • 34250019702 scopus 로고    scopus 로고
    • Explaining the decrease in U.S. Deaths from coronary disease, 1980-2000
    • Ford ES, Ajani UA, Croft JB, et al. Explaining the decrease in U.S. deaths from coronary disease, 1980-2000. N Engl J Med. 2007;356:2388-2398.
    • (2007) N Engl J Med , vol.356 , pp. 2388-2398
    • Ford, E.S.1    Ajani, U.A.2    Croft, J.B.3
  • 2
    • 84896690513 scopus 로고    scopus 로고
    • Prevalence of childhood and adult obesity in the United States, 2011-2012
    • Ogden CL, Carroll MD, Kit BK, et al. Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA. 2014;311:806-814.
    • (2014) JAMA , vol.311 , pp. 806-814
    • Ogden, C.L.1    Carroll, M.D.2    Kit, B.K.3
  • 3
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393-403.
    • (2002) N Engl J Med , vol.346 , pp. 393-403
    • Knowler, W.C.1    Barrett-Connor, E.2    Fowler, S.E.3
  • 4
    • 84882349072 scopus 로고    scopus 로고
    • Managing obesity in primary care practice: An overview with perspective from the POWER-UP study
    • Wadden TA, Volger S, Tsai AG, et al. Managing obesity in primary care practice: an overview with perspective from the POWER-UP study. Int J Obes (Lond). 2013;37(suppl 1):S3-S11.
    • (2013) Int J Obes (Lond) , vol.37 , pp. S3-S11
    • Wadden, T.A.1    Volger, S.2    Tsai, A.G.3
  • 5
    • 84891919414 scopus 로고    scopus 로고
    • Long-term drug treatment for obesity: A systematic and clinical review
    • Yanovski SZ, Yanovski JA. Long-term drug treatment for obesity: a systematic and clinical review. JAMA. 2014;311:74-86.
    • (2014) JAMA , vol.311 , pp. 74-86
    • Yanovski, S.Z.1    Yanovski, J.A.2
  • 7
    • 34249743161 scopus 로고    scopus 로고
    • Dinitrophenol and obesity: An early twentieth-century regulatory dilemma
    • Colman E. Dinitrophenol and obesity: an early twentieth-century regulatory dilemma. Regul Toxicol Pharmacol. 2007;48:115-117.
    • (2007) Regul Toxicol Pharmacol , vol.48 , pp. 115-117
    • Colman, E.1
  • 8
    • 0034700436 scopus 로고    scopus 로고
    • Phenylpropanolamine and the risk of hemorrhagic stroke
    • Kernan WN, Viscoli CM, Brass LM, et al. Phenylpropanolamine and the risk of hemorrhagic stroke. N Engl J Med. 2000;343:1826-1832.
    • (2000) N Engl J Med , vol.343 , pp. 1826-1832
    • Kernan, W.N.1    Viscoli, C.M.2    Brass, L.M.3
  • 9
    • 0026518794 scopus 로고
    • Long-term weight control study, I (weeks 0 to 34): The enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placebo
    • Weintraub M, Sundaresan PR, Madan M, et al. Long-term weight control study, I (weeks 0 to 34): the enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placebo. Clin Pharmacol Ther. 1992;51:586-594.
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 586-594
    • Weintraub, M.1    Sundaresan, P.R.2    Madan, M.3
  • 10
    • 0030876952 scopus 로고    scopus 로고
    • Valvular heart disease associated with fenfluramine-phentermine
    • Connolly HM, Crary JL, McGoon MD, et al. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med. 1997;337:581-588.
    • (1997) N Engl J Med , vol.337 , pp. 581-588
    • Connolly, H.M.1    Crary, J.L.2    McGoon, M.D.3
  • 11
    • 0032505060 scopus 로고    scopus 로고
    • Sustained-Release Dexfenfluramine Study Group. An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo
    • Weissman NJ, Tighe JF Jr, Gottdiener JS, et al; Sustained-Release Dexfenfluramine Study Group. An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo. N Engl J Med. 1998;339:725-732.
    • (1998) N Engl J Med , vol.339 , pp. 725-732
    • Weissman, N.J.1    Tighe, J.F.2    Gottdiener, J.S.3
  • 12
    • 9444287592 scopus 로고    scopus 로고
    • International Primary Pulmonary Hypertension Study Group. Appetite-suppressant drugs and the risk of primary pulmonary hypertension
    • Abenhaim L, Moride Y, Brenot F, et al; International Primary Pulmonary Hypertension Study Group. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. N Engl J Med. 1996;335:609-616.
    • (1996) N Engl J Med , vol.335 , pp. 609-616
    • Abenhaim, L.1    Moride, Y.2    Brenot, F.3
  • 14
    • 32644441249 scopus 로고    scopus 로고
    • Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: A randomized controlled trial
    • Pi-Sunyer FX, Aronne LJ, Heshmati HM, et al. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA. 2006;295:761-775.
    • (2006) JAMA , vol.295 , pp. 761-775
    • Pi-Sunyer, F.X.1    Aronne, L.J.2    Heshmati, H.M.3
  • 15
    • 84860330219 scopus 로고    scopus 로고
    • Food and Drug Administration's Obesity Drug Guidance Document: A short history
    • Colman E. Food and Drug Administration's Obesity Drug Guidance Document: a short history. Circulation. 2012;125:2156-2164.
    • (2012) Circulation , vol.125 , pp. 2156-2164
    • Colman, E.1
  • 16
    • 77956017429 scopus 로고    scopus 로고
    • Rimonabant for prevention of cardiovascular events (CRESCENDO): A randomised, multicentre, placebo-controlled trial
    • Topol EJ, Bousser MG, Fox KA, et al. Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial. Lancet. 2010;376:517-523.
    • (2010) Lancet , vol.376 , pp. 517-523
    • Topol, E.J.1    Bousser, M.G.2    Fox, K.A.3
  • 18
    • 77956284607 scopus 로고    scopus 로고
    • Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects
    • James WP, Caterson ID, Coutinho W, et al. Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N Engl J Med. 2010;363:905-917.
    • (2010) N Engl J Med , vol.363 , pp. 905-917
    • James, W.P.1    Caterson, I.D.2    Coutinho, W.3
  • 20
    • 62849107573 scopus 로고    scopus 로고
    • Body-mass index and cause-specific mortality in 900 000 adults: Collaborative analyses of 57 prospective studies
    • Whitlock G, Lewington S, Sherliker P, et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet. 2009;373:1083-1096.
    • (2009) Lancet , vol.373 , pp. 1083-1096
    • Whitlock, G.1    Lewington, S.2    Sherliker, P.3
  • 21
    • 34548090763 scopus 로고    scopus 로고
    • Effects of bariatric surgery on mortality in Swedish obese subjects
    • Sjöström L, Narbro K, Sjöström CD, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357:741-752.
    • (2007) N Engl J Med , vol.357 , pp. 741-752
    • Sjöström, L.1    Narbro, K.2    Sjöström, C.D.3
  • 22
    • 1042303480 scopus 로고    scopus 로고
    • XENical in the prevention of diabetes in obese subjects (XENDOS) study: A randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients
    • Torgerson JS, Hauptman J, Boldrin MN, et al. XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care. 2004;27:155-161.
    • (2004) Diabetes Care , vol.27 , pp. 155-161
    • Torgerson, J.S.1    Hauptman, J.2    Boldrin, M.N.3
  • 23
    • 84900335025 scopus 로고    scopus 로고
    • Bariatric surgery versus intensive medical therapy for diabetes - 3-year outcomes
    • Schauer PR, Bhatt DL, Kirwan JP, et al; STAMPEDE Investigators. Bariatric surgery versus intensive medical therapy for diabetes - 3-year outcomes. N Engl J Med. 2014;370:2002-2013.
    • (2014) N Engl J Med , vol.370 , pp. 2002-2013
    • Schauer, P.R.1    Bhatt, D.L.2    Kirwan, J.P.3
  • 24
    • 70349695858 scopus 로고    scopus 로고
    • Long-term weight loss from lifestyle intervention benefits blood pressure?: A systematic review
    • Aucott L, Rothnie H, McIntyre L, et al. Long-term weight loss from lifestyle intervention benefits blood pressure?: a systematic review. Hypertension. 2009;54:756-762.
    • (2009) Hypertension , vol.54 , pp. 756-762
    • Aucott, L.1    Rothnie, H.2    McIntyre, L.3
  • 25
    • 84878534607 scopus 로고    scopus 로고
    • Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: The Diabetes Surgery Study randomized clinical trial
    • Ikramuddin S, Korner J, Lee WJ, et al. Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. JAMA. 2013;309:2240-2249.
    • (2013) JAMA , vol.309 , pp. 2240-2249
    • Ikramuddin, S.1    Korner, J.2    Lee, W.J.3
  • 26
    • 0037022237 scopus 로고    scopus 로고
    • Weight loss reduces C-reactive protein levels in obese postmenopausal women
    • Tchernof A, Nolan A, Sites CK, et al. Weight loss reduces C-reactive protein levels in obese postmenopausal women. Circulation. 2002;105:564-569.
    • (2002) Circulation , vol.105 , pp. 564-569
    • Tchernof, A.1    Nolan, A.2    Sites, C.K.3
  • 28
    • 84880323061 scopus 로고    scopus 로고
    • Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes
    • Wing RR, Bolin P, Brancati FL, et al. Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med. 2013;369:145-154.
    • (2013) N Engl J Med , vol.369 , pp. 145-154
    • Wing, R.R.1    Bolin, P.2    Brancati, F.L.3
  • 29
    • 84856246606 scopus 로고    scopus 로고
    • Controlled-release phentermine/topiramate in severely obese adults: A randomized controlled trial (EQUIP)
    • Allison DB, Gadde KM, Garvey WT, et al. Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP). Obesity (Silver Spring). 2012;20:330-342.
    • (2012) Obesity (Silver Spring) , vol.20 , pp. 330-342
    • Allison, D.B.1    Gadde, K.M.2    Garvey, W.T.3
  • 30
    • 79954561234 scopus 로고    scopus 로고
    • Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): A randomised, placebo-controlled, phase 3 trial
    • Gadde KM, Allison DB, Ryan DH, et al. Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial. Lancet. 2011;377:1341-1352.
    • (2011) Lancet , vol.377 , pp. 1341-1352
    • Gadde, K.M.1    Allison, D.B.2    Ryan, D.H.3
  • 31
    • 84856388467 scopus 로고    scopus 로고
    • Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): A randomized, placebo-controlled, phase 3 extension study
    • Garvey WT, Ryan DH, Look M, et al. Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study. Am J Clin Nutr. 2012;95:297-308.
    • (2012) Am J Clin Nutr , vol.95 , pp. 297-308
    • Garvey, W.T.1    Ryan, D.H.2    Look, M.3
  • 32
    • 80053539943 scopus 로고    scopus 로고
    • A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: The BLOSSOM trial
    • Fidler MC, Sanchez M, Raether B, et al. A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trial. J Clin Endocrinol Metab. 2011;96:3067-3077.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 3067-3077
    • Fidler, M.C.1    Sanchez, M.2    Raether, B.3
  • 33
    • 84862869642 scopus 로고    scopus 로고
    • Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: The BLOOM-DM study
    • O'Neil PM, Smith SR, Weissman NJ, et al. Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study. Obesity (Silver Spring). 2012;20:1426-1436.
    • (2012) Obesity (Silver Spring) , vol.20 , pp. 1426-1436
    • O'Neil, P.M.1    Smith, S.R.2    Weissman, N.J.3
  • 34
    • 77954635020 scopus 로고    scopus 로고
    • Multicenter, placebo-controlled trial of lorcaserin for weight management
    • Smith SR, Weissman NJ, Anderson CM, et al. Multicenter, placebo-controlled trial of lorcaserin for weight management. N Engl J Med. 2010;363:245-256.
    • (2010) N Engl J Med , vol.363 , pp. 245-256
    • Smith, S.R.1    Weissman, N.J.2    Anderson, C.M.3
  • 35
    • 84879324574 scopus 로고    scopus 로고
    • A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II)
    • Apovian CM, Aronne L, Rubino D, et al. A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II). Obesity (Silver Spring). 2013;21:935-943.
    • (2013) Obesity (Silver Spring) , vol.21 , pp. 935-943
    • Apovian, C.M.1    Aronne, L.2    Rubino, D.3
  • 36
    • 77956057548 scopus 로고    scopus 로고
    • Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): A multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
    • Greenway FL, Fujioka K, Plodkowski RA, et al. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2010;376:595-605.
    • (2010) Lancet , vol.376 , pp. 595-605
    • Greenway, F.L.1    Fujioka, K.2    Plodkowski, R.A.3
  • 37
    • 77956904326 scopus 로고    scopus 로고
    • Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: The COR-BMOD trial
    • Wadden TA, Foreyt JP, Foster GD, et al. Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial. Obesity (Silver Spring). 2011;19:110-120.
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 110-120
    • Wadden, T.A.1    Foreyt, J.P.2    Foster, G.D.3
  • 38
    • 84891869792 scopus 로고    scopus 로고
    • Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes
    • Hollander P, Gupta AK, Plodkowski R, et al. Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes. Diabetes Care. 2013;36:4022-4029.
    • (2013) Diabetes Care , vol.36 , pp. 4022-4029
    • Hollander, P.1    Gupta, A.K.2    Plodkowski, R.3
  • 39
    • 84861930424 scopus 로고    scopus 로고
    • Do prescription stimulants increase the risk of adverse cardiovascular events?: A systematic review
    • Westover AN, Halm EA. Do prescription stimulants increase the risk of adverse cardiovascular events?: a systematic review. BMC Cardiovasc Disord. 2012;12:41.
    • (2012) BMC Cardiovasc Disord , vol.12 , pp. 41
    • Westover, A.N.1    Halm, E.A.2
  • 40
    • 0002807086 scopus 로고
    • Intermittent dobutamine in ambulatory outpatients with chronic cardiac failure
    • abstract
    • Dies F, Krell M, Whitlow P. Intermittent dobutamine in ambulatory outpatients with chronic cardiac failure (abstract). Circulation. 1986;74(suppl II):S38.
    • (1986) Circulation , vol.74 , pp. S38
    • Dies, F.1    Krell, M.2    Whitlow, P.3
  • 41
    • 82355175158 scopus 로고    scopus 로고
    • AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other Atherosclerotic Vascular Disease: 2011 update: A guideline from the American Heart Association and American College of Cardiology Foundation
    • Smith SC Jr, Benjamin EJ, Bonow RO, et al. AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other Atherosclerotic Vascular Disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation. Circulation. 2011;124:2458-2473.
    • (2011) Circulation , vol.124 , pp. 2458-2473
    • Smith, S.C.1    Benjamin, E.J.2    Bonow, R.O.3
  • 43
    • 85047697192 scopus 로고    scopus 로고
    • Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors
    • McMahon FG, Weinstein SP, Rowe E, et al. Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors. J Hum Hypertens. 2002;16:5-11.
    • (2002) J Hum Hypertens , vol.16 , pp. 5-11
    • McMahon, F.G.1    Weinstein, S.P.2    Rowe, E.3
  • 44
    • 0037178730 scopus 로고    scopus 로고
    • Activation of central melanocortin pathways by fenfluramine
    • Heisler LK, Cowley MA, Tecott LH, et al. Activation of central melanocortin pathways by fenfluramine. Science. 2002;297:609-611.
    • (2002) Science , vol.297 , pp. 609-611
    • Heisler, L.K.1    Cowley, M.A.2    Tecott, L.H.3
  • 45
    • 42449134961 scopus 로고    scopus 로고
    • Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: In vitro and in vivo pharmacological characterization
    • Thomsen WJ, Grottick AJ, Menzaghi F, et al. Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: in vitro and in vivo pharmacological characterization. J Pharmacol Exp Ther. 2008;325:577-587.
    • (2008) J Pharmacol Exp Ther , vol.325 , pp. 577-587
    • Thomsen, W.J.1    Grottick, A.J.2    Menzaghi, F.3
  • 46
    • 35548942643 scopus 로고    scopus 로고
    • Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways
    • Zhou L, Sutton GM, Rochford JJ, et al. Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways. Cell Metab. 2007;6:398-405.
    • (2007) Cell Metab , vol.6 , pp. 398-405
    • Zhou, L.1    Sutton, G.M.2    Rochford, J.J.3
  • 47
    • 33846017361 scopus 로고    scopus 로고
    • Drugs and valvular heart disease
    • Roth BL. Drugs and valvular heart disease. N Engl J Med. 2007;356:6-9.
    • (2007) N Engl J Med , vol.356 , pp. 6-9
    • Roth, B.L.1
  • 48
    • 0036799278 scopus 로고    scopus 로고
    • Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension
    • Launay JM, Hervé P, Peoc'h K, et al. Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension. Nat Med. 2002;8:1129-1135.
    • (2002) Nat Med , vol.8 , pp. 1129-1135
    • Launay, J.M.1    Hervé, P.2    Peoc'h, K.3
  • 49
    • 84884478505 scopus 로고    scopus 로고
    • Echocardiographic assessment of cardiac valvular regurgitation with lorcaserin from analysis of 3 phase 3 clinical trials
    • Weissman NJ, Sanchez M, Koch GG, et al. Echocardiographic assessment of cardiac valvular regurgitation with lorcaserin from analysis of 3 phase 3 clinical trials. Circ Cardiovasc Imaging. 2013;6:560-567.
    • (2013) Circ Cardiovasc Imaging , vol.6 , pp. 560-567
    • Weissman, N.J.1    Sanchez, M.2    Koch, G.G.3
  • 52
    • 0033039361 scopus 로고    scopus 로고
    • Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study)
    • Singh JP, Evans JC, Levy D, et al. Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study). Am J Cardiol. 1999;83:897-902.
    • (1999) Am J Cardiol , vol.83 , pp. 897-902
    • Singh, J.P.1    Evans, J.C.2    Levy, D.3
  • 54
    • 84903133961 scopus 로고    scopus 로고
    • 2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society
    • Jensen MD, Ryan DH, Apovian CM, et al. 2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation. 2013; doi:10.1161/01.cir.0000437739.71477.ee.
    • (2013) Circulation
    • Jensen, M.D.1    Ryan, D.H.2    Apovian, C.M.3
  • 56
    • 84866415211 scopus 로고    scopus 로고
    • Cardiovascular risk assessment in the development of new drugs for obesity
    • Hiatt WR, Goldfine AB, Kaul S. Cardiovascular risk assessment in the development of new drugs for obesity. JAMA. 2012;308:1099-1100.
    • (2012) JAMA , vol.308 , pp. 1099-1100
    • Hiatt, W.R.1    Goldfine, A.B.2    Kaul, S.3
  • 57
    • 84867773387 scopus 로고    scopus 로고
    • The FDA's assessment of two drugs for chronic weight management
    • Colman E, Golden J, Roberts M, et al. The FDA's assessment of two drugs for chronic weight management. N Engl J Med. 2012;367:1577-1579.
    • (2012) N Engl J Med , vol.367 , pp. 1577-1579
    • Colman, E.1    Golden, J.2    Roberts, M.3


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