-
1
-
-
34250019702
-
Explaining the decrease in U.S. Deaths from coronary disease, 1980-2000
-
Ford ES, Ajani UA, Croft JB, et al. Explaining the decrease in U.S. deaths from coronary disease, 1980-2000. N Engl J Med. 2007;356:2388-2398.
-
(2007)
N Engl J Med
, vol.356
, pp. 2388-2398
-
-
Ford, E.S.1
Ajani, U.A.2
Croft, J.B.3
-
2
-
-
84896690513
-
Prevalence of childhood and adult obesity in the United States, 2011-2012
-
Ogden CL, Carroll MD, Kit BK, et al. Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA. 2014;311:806-814.
-
(2014)
JAMA
, vol.311
, pp. 806-814
-
-
Ogden, C.L.1
Carroll, M.D.2
Kit, B.K.3
-
3
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393-403.
-
(2002)
N Engl J Med
, vol.346
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
-
4
-
-
84882349072
-
Managing obesity in primary care practice: An overview with perspective from the POWER-UP study
-
Wadden TA, Volger S, Tsai AG, et al. Managing obesity in primary care practice: an overview with perspective from the POWER-UP study. Int J Obes (Lond). 2013;37(suppl 1):S3-S11.
-
(2013)
Int J Obes (Lond)
, vol.37
, pp. S3-S11
-
-
Wadden, T.A.1
Volger, S.2
Tsai, A.G.3
-
5
-
-
84891919414
-
Long-term drug treatment for obesity: A systematic and clinical review
-
Yanovski SZ, Yanovski JA. Long-term drug treatment for obesity: a systematic and clinical review. JAMA. 2014;311:74-86.
-
(2014)
JAMA
, vol.311
, pp. 74-86
-
-
Yanovski, S.Z.1
Yanovski, J.A.2
-
7
-
-
34249743161
-
Dinitrophenol and obesity: An early twentieth-century regulatory dilemma
-
Colman E. Dinitrophenol and obesity: an early twentieth-century regulatory dilemma. Regul Toxicol Pharmacol. 2007;48:115-117.
-
(2007)
Regul Toxicol Pharmacol
, vol.48
, pp. 115-117
-
-
Colman, E.1
-
8
-
-
0034700436
-
Phenylpropanolamine and the risk of hemorrhagic stroke
-
Kernan WN, Viscoli CM, Brass LM, et al. Phenylpropanolamine and the risk of hemorrhagic stroke. N Engl J Med. 2000;343:1826-1832.
-
(2000)
N Engl J Med
, vol.343
, pp. 1826-1832
-
-
Kernan, W.N.1
Viscoli, C.M.2
Brass, L.M.3
-
9
-
-
0026518794
-
Long-term weight control study, I (weeks 0 to 34): The enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placebo
-
Weintraub M, Sundaresan PR, Madan M, et al. Long-term weight control study, I (weeks 0 to 34): the enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placebo. Clin Pharmacol Ther. 1992;51:586-594.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 586-594
-
-
Weintraub, M.1
Sundaresan, P.R.2
Madan, M.3
-
10
-
-
0030876952
-
Valvular heart disease associated with fenfluramine-phentermine
-
Connolly HM, Crary JL, McGoon MD, et al. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med. 1997;337:581-588.
-
(1997)
N Engl J Med
, vol.337
, pp. 581-588
-
-
Connolly, H.M.1
Crary, J.L.2
McGoon, M.D.3
-
11
-
-
0032505060
-
Sustained-Release Dexfenfluramine Study Group. An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo
-
Weissman NJ, Tighe JF Jr, Gottdiener JS, et al; Sustained-Release Dexfenfluramine Study Group. An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo. N Engl J Med. 1998;339:725-732.
-
(1998)
N Engl J Med
, vol.339
, pp. 725-732
-
-
Weissman, N.J.1
Tighe, J.F.2
Gottdiener, J.S.3
-
12
-
-
9444287592
-
International Primary Pulmonary Hypertension Study Group. Appetite-suppressant drugs and the risk of primary pulmonary hypertension
-
Abenhaim L, Moride Y, Brenot F, et al; International Primary Pulmonary Hypertension Study Group. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. N Engl J Med. 1996;335:609-616.
-
(1996)
N Engl J Med
, vol.335
, pp. 609-616
-
-
Abenhaim, L.1
Moride, Y.2
Brenot, F.3
-
14
-
-
32644441249
-
Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: A randomized controlled trial
-
Pi-Sunyer FX, Aronne LJ, Heshmati HM, et al. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA. 2006;295:761-775.
-
(2006)
JAMA
, vol.295
, pp. 761-775
-
-
Pi-Sunyer, F.X.1
Aronne, L.J.2
Heshmati, H.M.3
-
15
-
-
84860330219
-
Food and Drug Administration's Obesity Drug Guidance Document: A short history
-
Colman E. Food and Drug Administration's Obesity Drug Guidance Document: a short history. Circulation. 2012;125:2156-2164.
-
(2012)
Circulation
, vol.125
, pp. 2156-2164
-
-
Colman, E.1
-
16
-
-
77956017429
-
Rimonabant for prevention of cardiovascular events (CRESCENDO): A randomised, multicentre, placebo-controlled trial
-
Topol EJ, Bousser MG, Fox KA, et al. Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial. Lancet. 2010;376:517-523.
-
(2010)
Lancet
, vol.376
, pp. 517-523
-
-
Topol, E.J.1
Bousser, M.G.2
Fox, K.A.3
-
18
-
-
77956284607
-
Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects
-
James WP, Caterson ID, Coutinho W, et al. Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N Engl J Med. 2010;363:905-917.
-
(2010)
N Engl J Med
, vol.363
, pp. 905-917
-
-
James, W.P.1
Caterson, I.D.2
Coutinho, W.3
-
20
-
-
62849107573
-
Body-mass index and cause-specific mortality in 900 000 adults: Collaborative analyses of 57 prospective studies
-
Whitlock G, Lewington S, Sherliker P, et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet. 2009;373:1083-1096.
-
(2009)
Lancet
, vol.373
, pp. 1083-1096
-
-
Whitlock, G.1
Lewington, S.2
Sherliker, P.3
-
21
-
-
34548090763
-
Effects of bariatric surgery on mortality in Swedish obese subjects
-
Sjöström L, Narbro K, Sjöström CD, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357:741-752.
-
(2007)
N Engl J Med
, vol.357
, pp. 741-752
-
-
Sjöström, L.1
Narbro, K.2
Sjöström, C.D.3
-
22
-
-
1042303480
-
XENical in the prevention of diabetes in obese subjects (XENDOS) study: A randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients
-
Torgerson JS, Hauptman J, Boldrin MN, et al. XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care. 2004;27:155-161.
-
(2004)
Diabetes Care
, vol.27
, pp. 155-161
-
-
Torgerson, J.S.1
Hauptman, J.2
Boldrin, M.N.3
-
23
-
-
84900335025
-
Bariatric surgery versus intensive medical therapy for diabetes - 3-year outcomes
-
Schauer PR, Bhatt DL, Kirwan JP, et al; STAMPEDE Investigators. Bariatric surgery versus intensive medical therapy for diabetes - 3-year outcomes. N Engl J Med. 2014;370:2002-2013.
-
(2014)
N Engl J Med
, vol.370
, pp. 2002-2013
-
-
Schauer, P.R.1
Bhatt, D.L.2
Kirwan, J.P.3
-
24
-
-
70349695858
-
Long-term weight loss from lifestyle intervention benefits blood pressure?: A systematic review
-
Aucott L, Rothnie H, McIntyre L, et al. Long-term weight loss from lifestyle intervention benefits blood pressure?: a systematic review. Hypertension. 2009;54:756-762.
-
(2009)
Hypertension
, vol.54
, pp. 756-762
-
-
Aucott, L.1
Rothnie, H.2
McIntyre, L.3
-
25
-
-
84878534607
-
Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: The Diabetes Surgery Study randomized clinical trial
-
Ikramuddin S, Korner J, Lee WJ, et al. Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. JAMA. 2013;309:2240-2249.
-
(2013)
JAMA
, vol.309
, pp. 2240-2249
-
-
Ikramuddin, S.1
Korner, J.2
Lee, W.J.3
-
26
-
-
0037022237
-
Weight loss reduces C-reactive protein levels in obese postmenopausal women
-
Tchernof A, Nolan A, Sites CK, et al. Weight loss reduces C-reactive protein levels in obese postmenopausal women. Circulation. 2002;105:564-569.
-
(2002)
Circulation
, vol.105
, pp. 564-569
-
-
Tchernof, A.1
Nolan, A.2
Sites, C.K.3
-
28
-
-
84880323061
-
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes
-
Wing RR, Bolin P, Brancati FL, et al. Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med. 2013;369:145-154.
-
(2013)
N Engl J Med
, vol.369
, pp. 145-154
-
-
Wing, R.R.1
Bolin, P.2
Brancati, F.L.3
-
29
-
-
84856246606
-
Controlled-release phentermine/topiramate in severely obese adults: A randomized controlled trial (EQUIP)
-
Allison DB, Gadde KM, Garvey WT, et al. Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP). Obesity (Silver Spring). 2012;20:330-342.
-
(2012)
Obesity (Silver Spring)
, vol.20
, pp. 330-342
-
-
Allison, D.B.1
Gadde, K.M.2
Garvey, W.T.3
-
30
-
-
79954561234
-
Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): A randomised, placebo-controlled, phase 3 trial
-
Gadde KM, Allison DB, Ryan DH, et al. Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial. Lancet. 2011;377:1341-1352.
-
(2011)
Lancet
, vol.377
, pp. 1341-1352
-
-
Gadde, K.M.1
Allison, D.B.2
Ryan, D.H.3
-
31
-
-
84856388467
-
Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): A randomized, placebo-controlled, phase 3 extension study
-
Garvey WT, Ryan DH, Look M, et al. Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study. Am J Clin Nutr. 2012;95:297-308.
-
(2012)
Am J Clin Nutr
, vol.95
, pp. 297-308
-
-
Garvey, W.T.1
Ryan, D.H.2
Look, M.3
-
32
-
-
80053539943
-
A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: The BLOSSOM trial
-
Fidler MC, Sanchez M, Raether B, et al. A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trial. J Clin Endocrinol Metab. 2011;96:3067-3077.
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 3067-3077
-
-
Fidler, M.C.1
Sanchez, M.2
Raether, B.3
-
33
-
-
84862869642
-
Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: The BLOOM-DM study
-
O'Neil PM, Smith SR, Weissman NJ, et al. Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study. Obesity (Silver Spring). 2012;20:1426-1436.
-
(2012)
Obesity (Silver Spring)
, vol.20
, pp. 1426-1436
-
-
O'Neil, P.M.1
Smith, S.R.2
Weissman, N.J.3
-
34
-
-
77954635020
-
Multicenter, placebo-controlled trial of lorcaserin for weight management
-
Smith SR, Weissman NJ, Anderson CM, et al. Multicenter, placebo-controlled trial of lorcaserin for weight management. N Engl J Med. 2010;363:245-256.
-
(2010)
N Engl J Med
, vol.363
, pp. 245-256
-
-
Smith, S.R.1
Weissman, N.J.2
Anderson, C.M.3
-
35
-
-
84879324574
-
A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II)
-
Apovian CM, Aronne L, Rubino D, et al. A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II). Obesity (Silver Spring). 2013;21:935-943.
-
(2013)
Obesity (Silver Spring)
, vol.21
, pp. 935-943
-
-
Apovian, C.M.1
Aronne, L.2
Rubino, D.3
-
36
-
-
77956057548
-
Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): A multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
-
Greenway FL, Fujioka K, Plodkowski RA, et al. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2010;376:595-605.
-
(2010)
Lancet
, vol.376
, pp. 595-605
-
-
Greenway, F.L.1
Fujioka, K.2
Plodkowski, R.A.3
-
37
-
-
77956904326
-
Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: The COR-BMOD trial
-
Wadden TA, Foreyt JP, Foster GD, et al. Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial. Obesity (Silver Spring). 2011;19:110-120.
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 110-120
-
-
Wadden, T.A.1
Foreyt, J.P.2
Foster, G.D.3
-
38
-
-
84891869792
-
Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes
-
Hollander P, Gupta AK, Plodkowski R, et al. Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes. Diabetes Care. 2013;36:4022-4029.
-
(2013)
Diabetes Care
, vol.36
, pp. 4022-4029
-
-
Hollander, P.1
Gupta, A.K.2
Plodkowski, R.3
-
39
-
-
84861930424
-
Do prescription stimulants increase the risk of adverse cardiovascular events?: A systematic review
-
Westover AN, Halm EA. Do prescription stimulants increase the risk of adverse cardiovascular events?: a systematic review. BMC Cardiovasc Disord. 2012;12:41.
-
(2012)
BMC Cardiovasc Disord
, vol.12
, pp. 41
-
-
Westover, A.N.1
Halm, E.A.2
-
40
-
-
0002807086
-
Intermittent dobutamine in ambulatory outpatients with chronic cardiac failure
-
abstract
-
Dies F, Krell M, Whitlow P. Intermittent dobutamine in ambulatory outpatients with chronic cardiac failure (abstract). Circulation. 1986;74(suppl II):S38.
-
(1986)
Circulation
, vol.74
, pp. S38
-
-
Dies, F.1
Krell, M.2
Whitlow, P.3
-
41
-
-
82355175158
-
AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other Atherosclerotic Vascular Disease: 2011 update: A guideline from the American Heart Association and American College of Cardiology Foundation
-
Smith SC Jr, Benjamin EJ, Bonow RO, et al. AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other Atherosclerotic Vascular Disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation. Circulation. 2011;124:2458-2473.
-
(2011)
Circulation
, vol.124
, pp. 2458-2473
-
-
Smith, S.C.1
Benjamin, E.J.2
Bonow, R.O.3
-
43
-
-
85047697192
-
Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors
-
McMahon FG, Weinstein SP, Rowe E, et al. Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors. J Hum Hypertens. 2002;16:5-11.
-
(2002)
J Hum Hypertens
, vol.16
, pp. 5-11
-
-
McMahon, F.G.1
Weinstein, S.P.2
Rowe, E.3
-
44
-
-
0037178730
-
Activation of central melanocortin pathways by fenfluramine
-
Heisler LK, Cowley MA, Tecott LH, et al. Activation of central melanocortin pathways by fenfluramine. Science. 2002;297:609-611.
-
(2002)
Science
, vol.297
, pp. 609-611
-
-
Heisler, L.K.1
Cowley, M.A.2
Tecott, L.H.3
-
45
-
-
42449134961
-
Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: In vitro and in vivo pharmacological characterization
-
Thomsen WJ, Grottick AJ, Menzaghi F, et al. Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: in vitro and in vivo pharmacological characterization. J Pharmacol Exp Ther. 2008;325:577-587.
-
(2008)
J Pharmacol Exp Ther
, vol.325
, pp. 577-587
-
-
Thomsen, W.J.1
Grottick, A.J.2
Menzaghi, F.3
-
46
-
-
35548942643
-
Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways
-
Zhou L, Sutton GM, Rochford JJ, et al. Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways. Cell Metab. 2007;6:398-405.
-
(2007)
Cell Metab
, vol.6
, pp. 398-405
-
-
Zhou, L.1
Sutton, G.M.2
Rochford, J.J.3
-
47
-
-
33846017361
-
Drugs and valvular heart disease
-
Roth BL. Drugs and valvular heart disease. N Engl J Med. 2007;356:6-9.
-
(2007)
N Engl J Med
, vol.356
, pp. 6-9
-
-
Roth, B.L.1
-
48
-
-
0036799278
-
Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension
-
Launay JM, Hervé P, Peoc'h K, et al. Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension. Nat Med. 2002;8:1129-1135.
-
(2002)
Nat Med
, vol.8
, pp. 1129-1135
-
-
Launay, J.M.1
Hervé, P.2
Peoc'h, K.3
-
49
-
-
84884478505
-
Echocardiographic assessment of cardiac valvular regurgitation with lorcaserin from analysis of 3 phase 3 clinical trials
-
Weissman NJ, Sanchez M, Koch GG, et al. Echocardiographic assessment of cardiac valvular regurgitation with lorcaserin from analysis of 3 phase 3 clinical trials. Circ Cardiovasc Imaging. 2013;6:560-567.
-
(2013)
Circ Cardiovasc Imaging
, vol.6
, pp. 560-567
-
-
Weissman, N.J.1
Sanchez, M.2
Koch, G.G.3
-
52
-
-
0033039361
-
Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study)
-
Singh JP, Evans JC, Levy D, et al. Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study). Am J Cardiol. 1999;83:897-902.
-
(1999)
Am J Cardiol
, vol.83
, pp. 897-902
-
-
Singh, J.P.1
Evans, J.C.2
Levy, D.3
-
54
-
-
84903133961
-
2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society
-
Jensen MD, Ryan DH, Apovian CM, et al. 2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation. 2013; doi:10.1161/01.cir.0000437739.71477.ee.
-
(2013)
Circulation
-
-
Jensen, M.D.1
Ryan, D.H.2
Apovian, C.M.3
-
56
-
-
84866415211
-
Cardiovascular risk assessment in the development of new drugs for obesity
-
Hiatt WR, Goldfine AB, Kaul S. Cardiovascular risk assessment in the development of new drugs for obesity. JAMA. 2012;308:1099-1100.
-
(2012)
JAMA
, vol.308
, pp. 1099-1100
-
-
Hiatt, W.R.1
Goldfine, A.B.2
Kaul, S.3
-
57
-
-
84867773387
-
The FDA's assessment of two drugs for chronic weight management
-
Colman E, Golden J, Roberts M, et al. The FDA's assessment of two drugs for chronic weight management. N Engl J Med. 2012;367:1577-1579.
-
(2012)
N Engl J Med
, vol.367
, pp. 1577-1579
-
-
Colman, E.1
Golden, J.2
Roberts, M.3
|