Therapy of obese patients with cardiovascular disease

Current Opinion in Pharmacology

Volumn 13, Issue 2, 2013, Pages 200-204

  Jindal, Ankur ^a,b,c   Whaley Connell, Adam ^a,b,d,e,f   Brietzke, Stephen ^a,b,e   Sowers, James R ^a,b,e,f  

^a University of Missouri   (United States)

^b Department of Internal Medicine ^*  (United States)

^c UMass Memorial Healthcare   (United States)

^d Division of Nephrology and Hypertension   (United States)

^e Division of Endocrinology and Metabolism   (United States)

^f VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE PLUS NALTREXONE; EXENDIN 4; LIRAGLUTIDE; LORCASERIN; METFORMIN; PHENTERMINE PLUS TOPIRAMATE; PLACEBO; SEROTONIN AGONIST; SULFONYLUREA DERIVATIVE; TETRAHYDROLIPSTATIN;

BARIATRIC SURGERY; BEHAVIOR THERAPY; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; COGNITIVE DEFECT; COMORBIDITY; CONSTIPATION; DIABETES MELLITUS; DIARRHEA; DIZZINESS; DOSAGE SCHEDULE COMPARISON; DRUG BLOOD LEVEL; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG MEGADOSE; DRUG TOLERABILITY; DRUG WITHDRAWAL; DYSGEUSIA; ENERGY EXPENDITURE; EXERCISE; FLATULENCE; GASTROINTESTINAL SYMPTOM; HUMAN; HYPOGLYCEMIA; INSOMNIA; LIFESTYLE MODIFICATION; LOW CALORY DIET; MENTAL DISEASE; METABOLIC ACIDOSIS; NAUSEA; NEPHROLITHIASIS; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PARESTHESIA; PATIENT COMPLIANCE; PRIORITY JOURNAL; REVIEW; SEROTONIN SYNDROME; VITAMIN DEFICIENCY; VOMITING; WEIGHT REDUCTION; XEROSTOMIA;

ANTI-OBESITY AGENTS; BARIATRIC SURGERY; CARDIOVASCULAR DISEASES; EXERCISE THERAPY; HUMANS; OBESITY;

EID: 84879413562     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2012.12.006     Document Type: Review

References (37)

1. S. Klein, E. Fabbrini, and J.A. Romijn Williams Text Book of Endocrinology edn 12th 2011 Elsevier Saunders pp. 1605-1622
2. P.W. Franks, R.L. Hanson, W.C. Knowler, M.L. Sievers, P.H. Bennett, and H.C. Looker Childhood obesity, other cardiovascular risk factors, and premature death N Engl J Med 362 2010 485 493
3. P.W. Wilson, R.B. D'Agostino, L. Sullivan, H. Parise, and W.B. Kannel Overweight and obesity as determinants of cardiovascular risk: the Framingham experience Arch Intern Med 162 2002 1867 1872
4. U. Campia, M. Tesauro, and C. Cardillo Human obesity and endothelium-dependent responsiveness Br J Pharmacol 165 2012 561 573
5. H. Yatsuya, H. Toyoshima, K. Yamagishi, K. Tamakoshi, M. Taguri, A. Harada, Y. Ohashi, Y. Kita, Y. Naito, M. Yamada, and N. Tanabe Body mass index and risk of stroke and myocardial infarction in a relatively lean population: meta-analysis of 16 Japanese cohorts using individual data Circ Cardiovasc Qual Outcomes 3 2010 498 505
6. M. Juonala, C.G. Magnussen, G.S. Berenson, A. Venn, T.L. Burns, M.A. Sabin, S.R. Srinivasan, S.R. Daniels, P.H. Davis, W. Chen, and C. Sun Childhood adiposity, adult adiposity, and cardiovascular risk factors N Engl J Med 365 2011 1876 1885
7. E.W. Gregg, Y.J. Cheng, B.L. Cadwell, G. Imperatore, D.E. Williams, K.M. Flegal, K.M. Narayan, and D.F. Williamson Secular trends in cardiovascular disease risk factors according to body mass index in us adults JAMA 293 2005 1868 1874 (Pubitemid 40548183)
8. S.R. Smith, N.J. Weissman, C.M. Anderson, M. Sanchez, E. Chuang, S. Stubbe, H. Bays, and W.R. Shanahan Multicenter, placebo-controlled trial of lorcaserin for weight management N Engl J Med 363 2010 245 256
9. P.M. O'Neil, S.R. Smith, N.J. Weissman, M.C. Fidler, M. Sanchez, J. Zhang, B. Raether, C.M. Anderson, and W.R. Shanahan Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the bloom-dm study Obesity 20 2012 1426 1436
10. M.C. Fidler, M. Sanchez, B. Raether, N.J. Weissman, S.R. Smith, W.R. Shanahan, and C.M. Anderson A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: the blossom trial J Clin Endocrinol Metab 96 2011 3067 3077
11. W.J. Thomsen, A.J. Grottick, F. Menzaghi, H. Reyes-Saldana, S. Espitia, D. Yuskin, K. Whelan, M. Martin, M. Morgan, W. Chen, and H. Al-Shamma Lorcaserin, a novel selective human 5-hydroxytryptamine2c agonist: in vitro and in vivo pharmacological characterization J Pharmacol Exp Ther 325 2008 577 587 (Pubitemid 351574813)
12. D.B. Allison, K.M. Gadde, W.T. Garvey, C.A. Peterson, M.L. Schwiers, T. Najarian, P.Y. Tam, B. Troupin, and W.W. Day Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (equip) Obesity 20 2012 330 342
13. K.M. Gadde, D.B. Allison, D.H. Ryan, C.A. Peterson, B. Troupin, M.L. Schwiers, and W.W. Day Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (conquer): a randomised, placebo-controlled, phase 3 trial Lancet 377 2011 1341 1352
14. W.T. Garvey, D.H. Ryan, M. Look, K.M. Gadde, D.B. Allison, C.A. Peterson, M. Schwiers, W.W. Day, and C.H. Bowden Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (sequel): a randomized, placebo-controlled, phase 3 extension study Am J Clin Nutr 95 2012 297 308
15. A. Jindal, B. Stephen, and J.R. Sowers Obesity and the cardiorenal metabolic syndrome: therapeutic modalities and their efficacy in improving the cardiovascular and renal risk factors Cardiorenal Med 2 2012 314 327
16. J.S. Torgerson, J. Hauptman, M.N. Boldrin, and L. Sjostrom Xenical in the prevention of diabetes in obese subjects (xendos) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients Diabetes Care 27 2004 155 161 (Pubitemid 38196725)
17. A. Astrup, R. Carraro, N. Finer, A. Harper, M. Kunesova, M.E. Lean, L. Niskanen, M.F. Rasmussen, A. Rissanen, S. Rossner, and M.J. Savolainen Safety, tolerability and sustained weight loss over 2 years with the once-daily human glp-1 analog, liraglutide Int J Obes 36 2012 843 854
18. K. Niswender, X. Pi-Sunyer, J. Buse, K.H. Jensen, A.D. Toft, D. Russell-Jones, and B. Zinman Weight change with liraglutide and comparator therapies: an analysis of seven phase 3 trials from the liraglutide diabetes development programme Diabetes Obes Metab 3 2012 1463-1326
19. C.M. Apovian, R.M. Bergenstal, R.M. Cuddihy, Y. Qu, S. Lenox, M.S. Lewis, and L.C. Glass Effects of exenatide combined with lifestyle modification in patients with type 2 diabetes Am J Med 123 2010 e9 e17
20. A.S. Kelly, A.M. Metzig, K.D. Rudser, A.K. Fitch, C.K. Fox, B.M. Nathan, M.M. Deering, B.L. Schwartz, M.J. Abuzzahab, L.M. Gandrud, and A. Moran Exenatide as a weight-loss therapy in extreme pediatric obesity: a randomized, controlled pilot study Obesity 20 2012 364 370
21. M.S. Fineman, L.Z. Shen, K. Taylor, D.D. Kim, and A.D. Baron Effectiveness of progressive dose-escalation of exenatide (exendin-4) in reducing dose-limiting side effects in subjects with type 2 diabetes Diabetes Metab Res Rev 20 2004 411 417 (Pubitemid 39302967)
22. Long-term safety, tolerability, and weight loss associated with metformin in the diabetes prevention program outcomes, study Diabetes Care 35 2012 731 737
23. A. Golay Metformin and body weight Int J Obes 32 2008 61 72
24. H. Buchwald, Y. Avidor, E. Braunwald, M.D. Jensen, W. Pories, K. Fahrbach, and K. Schoelles Bariatric surgery: a systematic review and meta-analysis JAMA 292 2004 1724 1737 (Pubitemid 39346675)
25. H. Buchwald, R. Estok, K. Fahrbach, D. Banel, M.D. Jensen, W.J. Pories, J.P. Bantle, and I. Sledge Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis Am J Med 122 2009 248 256
26. J. Garb, G. Welch, S. Zagarins, J. Kuhn, and J. Romanelli Bariatric surgery for the treatment of morbid obesity: a meta-analysis of weight loss outcomes for laparoscopic adjustable gastric banding and laparoscopic gastric bypass Obes Surg 19 2009 1447 1455
27. D. Herron, and R. Roohipour Complications of roux-en-y gastric bypass and sleeve gastrectomy Abdom Imaging 3 2012
28. B.S. Bal, F.C. Finelli, T.R. Shope, and T.R. Koch Nutritional deficiencies after bariatric surgery Nat Rev Endocrinol 8 2012 544 556
29. A. Avenell, J. Broom, T.J. Brown, A. Poobalan, L. Aucott, S.C. Stearns, W.C. Smith, R.T. Jung, M.K. Campbell, and A.M. Grant Systematic review of the long-term effects and economic consequences of treatments for obesity and implications for health improvement Health Technol Assess 8 2004 1 182
30. I.L. Mertens, and L.F. Van Gaal Overweight, obesity, and blood pressure: the effects of modest weight reduction Obes Res 8 2000 270 278
31. S. Czernichow, M.J. Knol, L. Fezeu, and D.E. Grobbee Impact of orlistat initiation on cardiovascular treatment use: a 6-year population-based cohort study Eur J Prev Cardiol 19 2012 484 489
32. D. Rucker, R. Padwal, S.K. Li, C. Curioni, and D.C. Lau Long term pharmacotherapy for obesity and overweight: updated meta-analysis BMJ 335 2007 1194 1199 (Pubitemid 350273303)
33. L.M. Carlsson, M. Peltonen, S. Ahlin, A. Anveden, C. Bouchard, B. Carlsson, P. Jacobson, H. Lonroth, C. Maglio, I. Naslund, and C. Pirazzi Bariatric surgery and prevention of type 2 diabetes in Swedish obese subjects New Engl J Med 367 2012 695 704
34. J.B. Dixon, P.E. O'Brien, J. Playfair, L. Chapman, L.M. Schachter, S. Skinner, J. Proietto, M. Bailey, and M. Anderson Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial JAMA 299 2008 316 323 (Pubitemid 351159368)
35. P.R. Schauer, S.R. Kashyap, K. Wolski, S.A. Brethauer, J.P. Kirwan, C.E. Pothier, S. Thomas, B. Abood, S.E. Nissen, and D.L. Bhatt Bariatric surgery versus intensive medical therapy in obese patients with diabetes New Engl J Med 366 2012 1567 1576
36. A.E. Pontiroli, F. Frige, M. Paganelli, and F. Folli In morbid obesity, metabolic abnormalities and adhesion molecules correlate with visceral fat, not with subcutaneous fat: effect of weight loss through surgery Obes Surg 19 2009 745 750
37. A.E. Pontiroli, and A. Morabito Long-term prevention of mortality in morbid obesity through bariatric surgery. A systematic review and meta-analysis of trials performed with gastric banding and gastric bypass Ann Surg 253 2011 484 487