Aberrant activation of the GIMAP enhancer by oncogenic transcription factors in T-cell acute lymphoblastic leukemia

Leukemia

Volumn 31, Issue 8, 2017, Pages 1798-1807

  Liau, W S ^a   Tan, S H ^a   Ngoc, P C T ^a   Wang, C Q ^a,b   Tergaonkar, V ^b,c,d   Feng, H ^e   Gong, Z ^f   Osato, M ^a   Look, A T ^g,h   Sanda, T ^a,i  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g HARVARD MEDICAL SCHOOL   (United States)

^h BOSTON CHILDREN S HOSPITAL   (United States)

ⁱ Dept Medicine Endocrinol Diabet   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR TAL1; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; GIMAP1 PROTEIN, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE PROTEIN; ONCOPROTEIN; TAL1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; CRISPR CAS SYSTEM; DEVELOPMENT; DIFFERENTIATION; DOWN REGULATION; EMBRYO; ENHANCER REGION; GENE; GENE ACTIVATION; GENE CLUSTER; GENE LOCUS; GENE OVEREXPRESSION; GTPASE OF IMMUNITY ASSOCIATED PROTEIN GENE; HEMATOPOIETIC CELL; IN VIVO STUDY; LEUKEMIA; LEUKEMOGENESIS; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BINDING; T LYMPHOCYTE; THYMOCYTE; UPREGULATION; ANIMAL; C57BL MOUSE; GENETICS; HUMAN; MULTIGENE FAMILY; PHYSIOLOGY; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; TUMOR CELL LINE; ZEBRA FISH;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE, TUMOR; ENHANCER ELEMENTS, GENETIC; GTP-BINDING PROTEINS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MULTIGENE FAMILY; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION FACTORS; ZEBRAFISH;

EID: 85010904429     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2016.392     Document Type: Article

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