-
1
-
-
84947863792
-
Cellular therapies in trauma and critical care medicine: Forging new frontiers
-
Pati S, Pilia M, Grimsley JM et al. Cellular therapies in trauma and critical care medicine: Forging new frontiers. Shock 2015;44:505–523.
-
(2015)
Shock
, vol.44
, pp. 505-523
-
-
Pati, S.1
Pilia, M.2
Grimsley, J.M.3
-
2
-
-
84926388475
-
A controlled resuscitation strategy is feasible and safe in hypotensive trauma patients: Results of a prospective randomized pilot trial
-
discussion 695–687
-
Schreiber MA, Meier EN, Tisherman SA et al. A controlled resuscitation strategy is feasible and safe in hypotensive trauma patients: Results of a prospective randomized pilot trial. J Trauma Acute Care Surg 2015;78:687–695; discussion 695–687.
-
(2015)
. J Trauma Acute Care Surg
, vol.78
, pp. 687-695
-
-
Schreiber, M.A.1
Meier, E.N.2
Tisherman, S.A.3
-
3
-
-
0028100188
-
Immediate versus delayed fluid resuscitation for hypotensive patients with penetrating torso injuries
-
Bickell WH, Wall MJ, Jr., Pepe PE et al. Immediate versus delayed fluid resuscitation for hypotensive patients with penetrating torso injuries. N Engl J Med 1994;331:1105–1109.
-
(1994)
N Engl J Med
, vol.331
, pp. 1105-1109
-
-
Bickell, W.H.1
Wall, M.J.2
Pepe, P.E.3
-
4
-
-
21644454316
-
Emergency department management of mild traumatic brain injury in the USA
-
Bazarian JJ, McClung J, Cheng YT et al. Emergency department management of mild traumatic brain injury in the USA. Emerg Med J 2005;22:473–477.
-
(2005)
Emerg Med J
, vol.22
, pp. 473-477
-
-
Bazarian, J.J.1
McClung, J.2
Cheng, Y.T.3
-
5
-
-
0842303352
-
Management of brain and spine injuries
-
Chesnut RM. Management of brain and spine injuries. Crit Care Clin 2004;20:25–55.
-
(2004)
Crit Care Clin
, vol.20
, pp. 25-55
-
-
Chesnut, R.M.1
-
6
-
-
84857598895
-
A clinical comparison of penetrating and blunt traumatic brain injuries
-
Santiago LA, Oh BC, Dash PK et al. A clinical comparison of penetrating and blunt traumatic brain injuries. Brain Inj 2012;26:107–125.
-
(2012)
Brain Inj
, vol.26
, pp. 107-125
-
-
Santiago, L.A.1
Oh, B.C.2
Dash, P.K.3
-
7
-
-
84865211957
-
Galveston Brain Injury Conference 2010: Clinical and experimental aspects of blast injury
-
Masel BE, Bell RS, Brossart S et al. Galveston Brain Injury Conference 2010: Clinical and experimental aspects of blast injury. J Neurotrauma 2012;29:2143–2171.
-
(2012)
J Neurotrauma
, vol.29
, pp. 2143-2171
-
-
Masel, B.E.1
Bell, R.S.2
Brossart, S.3
-
8
-
-
84955613207
-
Modulating the endotheliopathy of trauma: Factor concentrate versus fresh frozen plasma
-
Pati S, Potter DR, Baimukanova G et al. Modulating the endotheliopathy of trauma: Factor concentrate versus fresh frozen plasma. J Trauma Acute Care Surg 2016;80:576–585.
-
(2016)
J Trauma Acute Care Surg
, vol.80
, pp. 576-585
-
-
Pati, S.1
Potter, D.R.2
Baimukanova, G.3
-
9
-
-
84867213778
-
Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention
-
Kumar A, Loane DJ. Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention. Brain Behav Immun 2012;26:1191–1201.
-
(2012)
Brain Behav Immun
, vol.26
, pp. 1191-1201
-
-
Kumar, A.1
Loane, D.J.2
-
10
-
-
84873397447
-
Inflammation and white matter degeneration persist for years after a single traumatic brain injury
-
Johnson VE, Stewart JE, Begbie FD et al. Inflammation and white matter degeneration persist for years after a single traumatic brain injury. Brain 2013;136:28–42.
-
(2013)
Brain
, vol.136
, pp. 28-42
-
-
Johnson, V.E.1
Stewart, J.E.2
Begbie, F.D.3
-
11
-
-
84885594842
-
Intracranial pressure monitoring in severe traumatic brain injury: Results from the American College of Surgeons Trauma Quality Improvement Program
-
Alali AS, Fowler RA, Mainprize TG et al. Intracranial pressure monitoring in severe traumatic brain injury: Results from the American College of Surgeons Trauma Quality Improvement Program. J Neurotrauma 2013;30:1737–1746.
-
(2013)
J Neurotrauma
, vol.30
, pp. 1737-1746
-
-
Alali, A.S.1
Fowler, R.A.2
Mainprize, T.G.3
-
12
-
-
79955127427
-
Decompressive craniectomy in diffuse traumatic brain injury
-
Cooper DJ, Rosenfeld JV, Murray L et al. Decompressive craniectomy in diffuse traumatic brain injury. N Engl J Med 2011;364:1493–1502.
-
(2011)
N Engl J Med
, vol.364
, pp. 1493-1502
-
-
Cooper, D.J.1
Rosenfeld, J.V.2
Murray, L.3
-
13
-
-
34547800263
-
Guidelines for the management of severe traumatic brain injury. XI. Anesthetics, analgesics, and sedatives
-
Bratton SL, Chestnut RM, Ghajar J et al. Guidelines for the management of severe traumatic brain injury. XI. Anesthetics, analgesics, and sedatives. J Neurotrauma 2007;24:S71–S76.
-
(2007)
J Neurotrauma
, vol.24
, pp. S71-S76
-
-
Bratton, S.L.1
Chestnut, R.M.2
Ghajar, J.3
-
14
-
-
84920026091
-
A clinical trial of progesterone for severe traumatic brain injury
-
Skolnick BE, Maas AI, Narayan RK et al. A clinical trial of progesterone for severe traumatic brain injury. N Engl J Med 2014;371:2467–2476.
-
(2014)
N Engl J Med
, vol.371
, pp. 2467-2476
-
-
Skolnick, B.E.1
Maas, A.I.2
Narayan, R.K.3
-
15
-
-
84920020062
-
Progesterone for traumatic brain injury–resisting the sirens' song
-
Schwamm LH. Progesterone for traumatic brain injury–resisting the sirens' song. N Engl J Med 2014;371:2522–2523.
-
(2014)
N Engl J Med
, vol.371
, pp. 2522-2523
-
-
Schwamm, L.H.1
-
16
-
-
78650981700
-
Human mesenchymal stem cells inhibit vascular permeability by modulating vascular endothelial cadherin/beta-catenin signaling
-
Pati S, Khakoo AY, Zhao J et al. Human mesenchymal stem cells inhibit vascular permeability by modulating vascular endothelial cadherin/beta-catenin signaling. Stem Cells Dev 2011;20:89–101.
-
(2011)
Stem Cells Dev
, vol.20
, pp. 89-101
-
-
Pati, S.1
Khakoo, A.Y.2
Zhao, J.3
-
17
-
-
84869749821
-
Mesenchymal stem cells regulate blood-brain barrier integrity through TIMP3 release after traumatic brain injury
-
Menge T, Zhao Y, Zhao J et al. Mesenchymal stem cells regulate blood-brain barrier integrity through TIMP3 release after traumatic brain injury. Sci Transl Med 2012;4:161ra150.
-
(2012)
Sci Transl Med
, vol.4
, pp. 161ra150
-
-
Menge, T.1
Zhao, Y.2
Zhao, J.3
-
18
-
-
84891517674
-
Autologous bone marrow mononuclear cells therapy attenuates activated microglial/macrophage response and improves spatial learning after traumatic brain injury
-
Bedi SS, Walker PA, Shah SK et al. Autologous bone marrow mononuclear cells therapy attenuates activated microglial/macrophage response and improves spatial learning after traumatic brain injury. J Trauma Acute Care Surg 2013;75:410–416.
-
(2013)
J Trauma Acute Care Surg
, vol.75
, pp. 410-416
-
-
Bedi, S.S.1
Walker, P.A.2
Shah, S.K.3
-
19
-
-
0041854545
-
Treatment of traumatic brain injury in adult rats with intravenous administration of human bone marrow stromal cells
-
discussion 702-693
-
Mahmood A, Lu D, Lu M et al. Treatment of traumatic brain injury in adult rats with intravenous administration of human bone marrow stromal cells. Neurosurgery 2003;53:697–702; discussion 702-693.
-
(2003)
Neurosurgery
, vol.53
, pp. 697-702
-
-
Mahmood, A.1
Lu, D.2
Lu, M.3
-
20
-
-
77956433599
-
Intravenous multipotent adult progenitor cell therapy for traumatic brain injury: Preserving the blood brain barrier via an interaction with splenocytes
-
Walker PA, Shah SK, Jimenez F et al. Intravenous multipotent adult progenitor cell therapy for traumatic brain injury: Preserving the blood brain barrier via an interaction with splenocytes. Exp Neurol 2010;225:341–352.
-
(2010)
Exp Neurol
, vol.225
, pp. 341-352
-
-
Walker, P.A.1
Shah, S.K.2
Jimenez, F.3
-
21
-
-
84866635677
-
Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: Modulation of the resident microglia population
-
Walker PA, Bedi SS, Shah SK et al. Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: Modulation of the resident microglia population. J Neuroinflammation 2012;9:228.
-
(2012)
J Neuroinflammation
, vol.9
, pp. 228
-
-
Walker, P.A.1
Bedi, S.S.2
Shah, S.K.3
-
22
-
-
84930189104
-
Multipotent adult progenitor cells decrease cold ischemic injury in ex vivo perfused human lungs: An initial pilot and feasibility study
-
La Francesca S, Ting AE, Sakamoto J et al. Multipotent adult progenitor cells decrease cold ischemic injury in ex vivo perfused human lungs: An initial pilot and feasibility study. Transplant Res 2014;3:19.
-
(2014)
Transplant Res
, vol.3
, pp. 19
-
-
La Francesca, S.1
Ting, A.E.2
Sakamoto, J.3
-
23
-
-
84953264179
-
TIMP3 attenuates the loss of neural stem cells, mature neurons and neurocognitive dysfunction in traumatic brain injury
-
Gibb SL, Zhao Y, Potter D et al. TIMP3 attenuates the loss of neural stem cells, mature neurons and neurocognitive dysfunction in traumatic brain injury. Stem Cells 2015;33:3530–3544.
-
(2015)
Stem Cells
, vol.33
, pp. 3530-3544
-
-
Gibb, S.L.1
Zhao, Y.2
Potter, D.3
-
24
-
-
66249096305
-
Pulmonary passage is a major obstacle for intravenous stem cell delivery: The pulmonary first-pass effect
-
Fischer UM, Harting MT, Jimenez F et al. Pulmonary passage is a major obstacle for intravenous stem cell delivery: The pulmonary first-pass effect. Stem Cells Dev 2009;18:683–692.
-
(2009)
Stem Cells Dev
, vol.18
, pp. 683-692
-
-
Fischer, U.M.1
Harting, M.T.2
Jimenez, F.3
-
25
-
-
84953295050
-
Chromatographically isolated CD63+CD81+ extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI
-
Kim DK, Nishida H, An SY et al. Chromatographically isolated CD63+CD81+ extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI. Proc Natl Acad Sci USA 2016;113:170–175.
-
(2016)
Proc Natl Acad Sci USA
, vol.113
, pp. 170-175
-
-
Kim, D.K.1
Nishida, H.2
An, S.Y.3
-
26
-
-
84922431269
-
Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: The PROPPR randomized clinical trial
-
Holcomb JB, Tilley BC, Baraniuk S et al. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: The PROPPR randomized clinical trial. JAMA 2015;313:471–482.
-
(2015)
JAMA
, vol.313
, pp. 471-482
-
-
Holcomb, J.B.1
Tilley, B.C.2
Baraniuk, S.3
-
27
-
-
84903705384
-
Acute kidney injury and chronic kidney disease as interconnected syndromes
-
Chawla LS, Eggers PW, Star RA et al. Acute kidney injury and chronic kidney disease as interconnected syndromes. N Engl J Med 2014;371:58–66.
-
(2014)
N Engl J Med
, vol.371
, pp. 58-66
-
-
Chawla, L.S.1
Eggers, P.W.2
Star, R.A.3
-
28
-
-
84864598081
-
Therapeutic potential of mesenchymal stem cell-derived microvesicles
-
Biancone L, Bruno S, Deregibus MC et al. Therapeutic potential of mesenchymal stem cell-derived microvesicles. Nephrol Dial Transplant 2012;27:3037–3042.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 3037-3042
-
-
Biancone, L.1
Bruno, S.2
Deregibus, M.C.3
-
29
-
-
84858185865
-
Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury
-
Bruno S, Grange C, Collino F et al. Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury. PLoS One 2012;7:e33115.
-
(2012)
PLoS One
, vol.7
-
-
Bruno, S.1
Grange, C.2
Collino, F.3
-
30
-
-
79955571241
-
Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury
-
Gatti S, Bruno S, Deregibus MC et al. Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury. Nephrol Dial Transplant 2011;26:1474–1483.
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 1474-1483
-
-
Gatti, S.1
Bruno, S.2
Deregibus, M.C.3
-
31
-
-
49949096866
-
The impact of development of acute lung injury on hospital mortality in critically ill trauma patients
-
Shah CV, Localio AR, Lanken PN et al. The impact of development of acute lung injury on hospital mortality in critically ill trauma patients. Crit Care Med 2008;36:2309–2315.
-
(2008)
Crit Care Med
, vol.36
, pp. 2309-2315
-
-
Shah, C.V.1
Localio, A.R.2
Lanken, P.N.3
-
32
-
-
84958260063
-
The acute respiratory distress syndrome following isolated severe traumatic brain injury
-
Hendrickson CM, Howard BM, Kornblith LZ et al. The acute respiratory distress syndrome following isolated severe traumatic brain injury. J Trauma Acute Care Surg 2016;80:989–997.
-
(2016)
J Trauma Acute Care Surg
, vol.80
, pp. 989-997
-
-
Hendrickson, C.M.1
Howard, B.M.2
Kornblith, L.Z.3
-
33
-
-
80053282797
-
Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock
-
Pati S, Gerber MH, Menge TD et al. Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock. PLoS One 2011;6:e25171.
-
(2011)
PLoS One
, vol.6
-
-
Pati, S.1
Gerber, M.H.2
Menge, T.D.3
-
34
-
-
84942586605
-
Mesenchymal stem cells reverse bone marrow dysfunction following injury and stress
-
Gore AV, Bible LE, Livingston DH et al. Mesenchymal stem cells reverse bone marrow dysfunction following injury and stress. J Trauma Acute Care Surg 2015;79:602–608.
-
(2015)
J Trauma Acute Care Surg
, vol.79
, pp. 602-608
-
-
Gore, A.V.1
Bible, L.E.2
Livingston, D.H.3
-
35
-
-
84971320866
-
Sepsis: Pathophysiology and clinical management
-
Gotts JE, Matthay MA. Sepsis: Pathophysiology and clinical management. BMJ 2016;353:i1585.
-
(2016)
BMJ
, vol.353
, pp. i1585
-
-
Gotts, J.E.1
Matthay, M.A.2
-
36
-
-
58149326737
-
Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production
-
Nemeth K, Leelahavanichkul A, Yuen PS et al. Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production. Nat Med 2009;15:42–49.
-
(2009)
Nat Med
, vol.15
, pp. 42-49
-
-
Nemeth, K.1
Leelahavanichkul, A.2
Yuen, P.S.3
-
37
-
-
77956246824
-
Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis
-
Mei SH, Haitsma JJ, Dos Santos CC et al. Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med 2010;182:1047–1057.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 1047-1057
-
-
Mei, S.H.1
Haitsma, J.J.2
Dos Santos, C.C.3
-
38
-
-
84861162374
-
Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes
-
Krasnodembskaya A, Samarani G, Song Y et al. Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes. Am J Physiol Lung Cell Mol Physiol 2012;302:L1003–L1013.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.302
, pp. L1003-L1013
-
-
Krasnodembskaya, A.1
Samarani, G.2
Song, Y.3
-
39
-
-
84919859861
-
Mesenchymal stem cells: Mechanisms of potential therapeutic benefit in ARDS and sepsis
-
Walter J, Ware LB, Matthay MA. Mesenchymal stem cells: Mechanisms of potential therapeutic benefit in ARDS and sepsis. Lancet Respir Med 2014;2:1016–1026.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 1016-1026
-
-
Walter, J.1
Ware, L.B.2
Matthay, M.A.3
-
40
-
-
34548610480
-
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice
-
Gupta N, Su X, Popov B et al. Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol 2007;179:1855–1863.
-
(2007)
J Immunol
, vol.179
, pp. 1855-1863
-
-
Gupta, N.1
Su, X.2
Popov, B.3
-
41
-
-
84937678877
-
Human mesenchymal stem (stromal) cells promote the resolution of acute lung injury in part through lipoxin A4
-
Fang X, Abbott J, Cheng L et al. Human mesenchymal stem (stromal) cells promote the resolution of acute lung injury in part through lipoxin A4. J Immunol 2015;195:875–881.
-
(2015)
J Immunol
, vol.195
, pp. 875-881
-
-
Fang, X.1
Abbott, J.2
Cheng, L.3
-
42
-
-
70349392958
-
Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung
-
Lee JW, Fang X, Gupta N et al. Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung. Proc Natl Acad Sci USA 2009;106:16357–16362.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16357-16362
-
-
Lee, J.W.1
Fang, X.2
Gupta, N.3
-
43
-
-
84861873276
-
Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia
-
Gupta N, Krasnodembskaya A, Kapetanaki M et al. Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia. Thorax 2012;67:533–539.
-
(2012)
Thorax
, vol.67
, pp. 533-539
-
-
Gupta, N.1
Krasnodembskaya, A.2
Kapetanaki, M.3
-
44
-
-
78651059830
-
Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37
-
Krasnodembskaya A, Song Y, Fang X et al. Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37. Stem Cells 2010;28:2229–2238.
-
(2010)
Stem Cells
, vol.28
, pp. 2229-2238
-
-
Krasnodembskaya, A.1
Song, Y.2
Fang, X.3
-
45
-
-
84872522183
-
Therapeutic effects of human mesenchymal stem cells in ex vivo human lungs injured with live bacteria
-
Lee JW, Krasnodembskaya A, McKenna DH et al. Therapeutic effects of human mesenchymal stem cells in ex vivo human lungs injured with live bacteria. Am J Respir Crit Care Med 2013;187:751–760.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 751-760
-
-
Lee, J.W.1
Krasnodembskaya, A.2
McKenna, D.H.3
-
46
-
-
84905983559
-
Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia
-
Asmussen S, Ito H, Traber DL et al. Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia. Thorax 2014;69:819–825.
-
(2014)
Thorax
, vol.69
, pp. 819-825
-
-
Asmussen, S.1
Ito, H.2
Traber, D.L.3
-
47
-
-
84939236722
-
Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat
-
Devaney J, Horie S, Masterson C et al. Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat. Thorax 2015;70:625–635.
-
(2015)
Thorax
, vol.70
, pp. 625-635
-
-
Devaney, J.1
Horie, S.2
Masterson, C.3
-
48
-
-
84906901861
-
Influenza causes prolonged disruption of the alveolar-capillary barrier in mice unresponsive to mesenchymal stem cell therapy
-
Gotts JE, Abbott J, Matthay MA. Influenza causes prolonged disruption of the alveolar-capillary barrier in mice unresponsive to mesenchymal stem cell therapy. Am J Physiol Lung Cell Mol Physiol 2014;307:L395–L406.
-
(2014)
Am J Physiol Lung Cell Mol Physiol
, vol.307
, pp. L395-L406
-
-
Gotts, J.E.1
Abbott, J.2
Matthay, M.A.3
-
49
-
-
84893617037
-
Mesenchymal stromal (stem) cell therapy: An emerging immunomodulatory strategy for the adjunctive treatment of sepsis
-
Liles WC, Matthay MA, Dos Santos CC et al. Mesenchymal stromal (stem) cell therapy: An emerging immunomodulatory strategy for the adjunctive treatment of sepsis. Am J Respir Crit Care Med 2014;189:363–364.
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 363-364
-
-
Liles, W.C.1
Matthay, M.A.2
Dos Santos, C.C.3
-
50
-
-
84962128706
-
Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo
-
Chan MC, Kuok DI, Leung CY et al. Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo. Proc Natl Acad Sci USA 2016;113:3621–3626.
-
(2016)
Proc Natl Acad Sci USA
, vol.113
, pp. 3621-3626
-
-
Chan, M.C.1
Kuok, D.I.2
Leung, C.Y.3
-
51
-
-
84914171420
-
Cell-based therapy for acute organ injury: Preclinical evidence and ongoing clinical trials using mesenchymal stem cells
-
Monsel A, Zhu YG, Gennai S et al. Cell-based therapy for acute organ injury: Preclinical evidence and ongoing clinical trials using mesenchymal stem cells. Anesthesiology 2014;121:1099–1121.
-
(2014)
Anesthesiology
, vol.121
, pp. 1099-1121
-
-
Monsel, A.1
Zhu, Y.G.2
Gennai, S.3
-
52
-
-
13544249606
-
Human mesenchymal stem cells modulate allogeneic immune cell responses
-
Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005;105:1815–1822.
-
(2005)
Blood
, vol.105
, pp. 1815-1822
-
-
Aggarwal, S.1
Pittenger, M.F.2
-
53
-
-
84860238652
-
Multipotent mesenchymal stromal cells and the innate immune system
-
Le Blanc K, Mougiakakos D. Multipotent mesenchymal stromal cells and the innate immune system. Nat Rev Immunol 2012;12:383–396.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 383-396
-
-
Le Blanc, K.1
Mougiakakos, D.2
-
54
-
-
36348977575
-
Immunomodulatory properties of mesenchymal stromal cells
-
Nauta AJ, Fibbe WE. Immunomodulatory properties of mesenchymal stromal cells. Blood 2007;110:3499–3506.
-
(2007)
Blood
, vol.110
, pp. 3499-3506
-
-
Nauta, A.J.1
Fibbe, W.E.2
-
55
-
-
79961212723
-
Human multipotent stromal cells attenuate lipopolysaccharide-induced acute lung injury in mice via secretion of tumor necrosis factor-alpha-induced protein 6
-
Danchuk S, Ylostalo JH, Hossain F et al. Human multipotent stromal cells attenuate lipopolysaccharide-induced acute lung injury in mice via secretion of tumor necrosis factor-alpha-induced protein 6. Stem Cell Res Ther 2011;2:27.
-
(2011)
Stem Cell Res Ther
, vol.2
, pp. 27
-
-
Danchuk, S.1
Ylostalo, J.H.2
Hossain, F.3
-
56
-
-
77954982590
-
Interleukin-10 delivery via mesenchymal stem cells: A novel gene therapy approach to prevent lung ischemia-reperfusion injury
-
Manning E, Pham S, Li S et al. Interleukin-10 delivery via mesenchymal stem cells: A novel gene therapy approach to prevent lung ischemia-reperfusion injury. Hum Gene Ther 2010;21:713–727.
-
(2010)
Hum Gene Ther
, vol.21
, pp. 713-727
-
-
Manning, E.1
Pham, S.2
Li, S.3
-
57
-
-
34547402979
-
Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury
-
Ortiz LA, Dutreil M, Fattman C et al. Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury. Proc Natl Acad Sci USA 2007;104:11002–11007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 11002-11007
-
-
Ortiz, L.A.1
Dutreil, M.2
Fattman, C.3
-
58
-
-
0037093058
-
Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
-
Di Nicola M, Carlo-Stella C, Magni M et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002;99:3838–3843.
-
(2002)
Blood
, vol.99
, pp. 3838-3843
-
-
Di Nicola, M.1
Carlo-Stella, C.2
Magni, M.3
-
59
-
-
70449527554
-
Mesenchymal stem cell-educated macrophages: A novel type of alternatively activated macrophages
-
Kim J, Hematti P. Mesenchymal stem cell-educated macrophages: A novel type of alternatively activated macrophages. Exp Hematol 2009;37:1445–1453.
-
(2009)
Exp Hematol
, vol.37
, pp. 1445-1453
-
-
Kim, J.1
Hematti, P.2
-
60
-
-
77949537626
-
Mouse bone marrow-derived mesenchymal stromal cells turn activated macrophages into a regulatory-like profile
-
Maggini J, Mirkin G, Bognanni I et al. Mouse bone marrow-derived mesenchymal stromal cells turn activated macrophages into a regulatory-like profile. PLoS One 2010;5:e9252.
-
(2010)
PLoS One
, vol.5
-
-
Maggini, J.1
Mirkin, G.2
Bognanni, I.3
-
61
-
-
78149335954
-
Human gingiva-derived mesenchymal stem cells elicit polarization of m2 macrophages and enhance cutaneous wound healing
-
Zhang Q-Z, Su W-R, Shi S-H et al. Human gingiva-derived mesenchymal stem cells elicit polarization of m2 macrophages and enhance cutaneous wound healing. Stem Cells 2010;28:1856–1868.
-
(2010)
Stem Cells
, vol.28
, pp. 1856-1868
-
-
Zhang, Q.-Z.1
Su, W.-R.2
Shi, S.-H.3
-
62
-
-
18544371666
-
Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells
-
Jiang X-X, Zhang Y, Liu B et al. Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells. Blood 2005;105:4120–4126.
-
(2005)
Blood
, vol.105
, pp. 4120-4126
-
-
Jiang, X.-X.1
Zhang, Y.2
Liu, B.3
-
63
-
-
33746898242
-
Mesenchymal stem cells inhibit generation and function of both CD34+-derived and monocyte-derived dendritic cells
-
Nauta AJ, Kruisselbrink AB, Lurvink E et al. Mesenchymal stem cells inhibit generation and function of both CD34+-derived and monocyte-derived dendritic cells. J Immunol 2006;177:2080–2087.
-
(2006)
J Immunol
, vol.177
, pp. 2080-2087
-
-
Nauta, A.J.1
Kruisselbrink, A.B.2
Lurvink, E.3
-
64
-
-
27744541175
-
Interaction between human NK cells and bone marrow stromal cells induces NK cell triggering: Role of NKp30 and NKG2D receptors
-
Poggi A, Prevosto C, Massaro A-M et al. Interaction between human NK cells and bone marrow stromal cells induces NK cell triggering: Role of NKp30 and NKG2D receptors. J Immunol 2005;175:6352–6360.
-
(2005)
J Immunol
, vol.175
, pp. 6352-6360
-
-
Poggi, A.1
Prevosto, C.2
Massaro, A.-M.3
-
65
-
-
0242300602
-
Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells
-
Rasmusson I, Ringden O, Sundberg B et al. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation 2003;76:1208–1213.
-
(2003)
Transplantation
, vol.76
, pp. 1208-1213
-
-
Rasmusson, I.1
Ringden, O.2
Sundberg, B.3
-
66
-
-
32644438233
-
Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation
-
Spaggiari GM, Capobianco A, Becchetti S et al. Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation. Blood 2006;107:1484–1490.
-
(2006)
Blood
, vol.107
, pp. 1484-1490
-
-
Spaggiari, G.M.1
Capobianco, A.2
Becchetti, S.3
-
67
-
-
38649105374
-
Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
-
Ren G, Zhang L, Zhao X et al. Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2008;2:141–150.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 141-150
-
-
Ren, G.1
Zhang, L.2
Zhao, X.3
-
68
-
-
0042740515
-
Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex
-
Le Blanc K, Tammik L, Sundberg B et al. Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex. Scand J Immunol 2003;57:11–20.
-
(2003)
Scand J Immunol
, vol.57
, pp. 11-20
-
-
Le Blanc, K.1
Tammik, L.2
Sundberg, B.3
-
69
-
-
0141886188
-
Veto-like activity of mesenchymal stem cells: Functional discrimination between cellular responses to alloantigens and recall antigens
-
Potian JA, Aviv H, Ponzio NM et al. Veto-like activity of mesenchymal stem cells: Functional discrimination between cellular responses to alloantigens and recall antigens. J Immunol 2003;171:3426–3434.
-
(2003)
J Immunol
, vol.171
, pp. 3426-3434
-
-
Potian, J.A.1
Aviv, H.2
Ponzio, N.M.3
-
70
-
-
80053153051
-
Mesenchymal stem cell inhibition of T-helper 17 cell- differentiation is triggered by cell-cell contact and mediated by prostaglandin E2 via the EP4 receptor
-
Duffy MM, Pindjakova J, Hanley SA et al. Mesenchymal stem cell inhibition of T-helper 17 cell- differentiation is triggered by cell-cell contact and mediated by prostaglandin E2 via the EP4 receptor. Eur J Immunol 2011;41:2840–2851.
-
(2011)
Eur J Immunol
, vol.41
, pp. 2840-2851
-
-
Duffy, M.M.1
Pindjakova, J.2
Hanley, S.A.3
-
71
-
-
77956215701
-
Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T regulatory cell phenotype
-
Ghannam S, Pene J, Torcy-Moquet G et al. Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T regulatory cell phenotype. J Immunol 2010;185:302–312.
-
(2010)
J Immunol
, vol.185
, pp. 302-312
-
-
Ghannam, S.1
Pene, J.2
Torcy-Moquet, G.3
-
72
-
-
84879124355
-
Mesenchymal stromal cells inhibit Th17 but not regulatory T-cell differentiation
-
Tatara R, Ozaki K, Kikuchi Y et al. Mesenchymal stromal cells inhibit Th17 but not regulatory T-cell differentiation. J Cytother 2011;13:686–694.
-
(2011)
J Cytother
, vol.13
, pp. 686-694
-
-
Tatara, R.1
Ozaki, K.2
Kikuchi, Y.3
-
73
-
-
79959461779
-
Intrapulmonary delivery of human umbilical cord mesenchymal stem cells attenuates acute lung injury by expanding CD4+CD25+ Forkhead Boxp3 (FOXP3)+ regulatory T cells and balancing anti- and pro-inflammatory factors
-
Sun J, Han Z-B, Liao W et al. Intrapulmonary delivery of human umbilical cord mesenchymal stem cells attenuates acute lung injury by expanding CD4+CD25+ Forkhead Boxp3 (FOXP3)+ regulatory T cells and balancing anti- and pro-inflammatory factors. Cell Physiol Biochem 2011;27:587–596.
-
(2011)
Cell Physiol Biochem
, vol.27
, pp. 587-596
-
-
Sun, J.1
Han, Z.-B.2
Liao, W.3
-
74
-
-
50249158511
-
Mesenchymal stem cells in health and disease
-
Uccelli A, Moretta L, Pistoia V et al. Mesenchymal stem cells in health and disease. Nat Rev Immunol 2008;8:726–736.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 726-736
-
-
Uccelli, A.1
Moretta, L.2
Pistoia, V.3
-
75
-
-
85027941877
-
Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase
-
Meisel R, Brockers S, Heseler K et al. Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase. Leukemia 2011;25:648–654.
-
(2011)
Leukemia
, vol.25
, pp. 648-654
-
-
Meisel, R.1
Brockers, S.2
Heseler, K.3
-
76
-
-
78649590402
-
Tissue-resident mesenchymal stem cells attract peripheral blood neutrophils and enhance their inflammatory activity in response to microbial challenge
-
Brandau S, Jakob M, Hemeda H et al. Tissue-resident mesenchymal stem cells attract peripheral blood neutrophils and enhance their inflammatory activity in response to microbial challenge. J Leukoc Biol 2010;88:1005–1015.
-
(2010)
J Leukoc Biol
, vol.88
, pp. 1005-1015
-
-
Brandau, S.1
Jakob, M.2
Hemeda, H.3
-
77
-
-
79957598130
-
Toll-like receptor-3-activated human mesenchymal stromal cells significantly prolong the survival and function of neutrophils
-
Cassatella MA, Mosna F, Micheletti A et al. Toll-like receptor-3-activated human mesenchymal stromal cells significantly prolong the survival and function of neutrophils. Stem Cells 2011;29:1001–1011.
-
(2011)
Stem Cells
, vol.29
, pp. 1001-1011
-
-
Cassatella, M.A.1
Mosna, F.2
Micheletti, A.3
-
78
-
-
77956246824
-
Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis
-
Mei SHJ, Haitsma JJ, Dos Santos CC et al. Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med 2010;182:1047–1057.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 1047-1057
-
-
Mei, S.H.J.1
Haitsma, J.J.2
Dos Santos, C.C.3
-
79
-
-
38349048723
-
Human mesenchymal stem cells inhibit neutrophil apoptosis: A model for neutrophil preservation in the bone marrow niche
-
Raffaghello L, Bianchi G, Bertolotto M et al. Human mesenchymal stem cells inhibit neutrophil apoptosis: A model for neutrophil preservation in the bone marrow niche. Stem Cells 2008;26:151–162.
-
(2008)
Stem Cells
, vol.26
, pp. 151-162
-
-
Raffaghello, L.1
Bianchi, G.2
Bertolotto, M.3
-
80
-
-
84861162374
-
Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes
-
Krasnodembskaya A, Samarani G, Song Y et al. Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes. Am J Physiol Lung Cell Mol Physiol 2012;302:L1003–L1013.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.302
, pp. L1003-L1013
-
-
Krasnodembskaya, A.1
Samarani, G.2
Song, Y.3
-
81
-
-
84872522183
-
Therapeutic effects of human mesenchymal stem cells in ex vivo human lungs injured with live bacteria
-
Lee JW, Krasnodembskaya A, McKenna DH et al. Therapeutic effects of human mesenchymal stem cells in ex vivo human lungs injured with live bacteria. Am J Respir Crit Care Med 2013;187:751–760.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 751-760
-
-
Lee, J.W.1
Krasnodembskaya, A.2
McKenna, D.H.3
-
82
-
-
84865137387
-
Nrf-2 overexpression in mesenchymal stem cells reduces oxidative stress-induced apoptosis and cytotoxicity
-
Mohammadzadeh M, Halabian R, Gharehbaghian A et al. Nrf-2 overexpression in mesenchymal stem cells reduces oxidative stress-induced apoptosis and cytotoxicity. Cell Stress Chaperones 2012;17:553–565.
-
(2012)
Cell Stress Chaperones
, vol.17
, pp. 553-565
-
-
Mohammadzadeh, M.1
Halabian, R.2
Gharehbaghian, A.3
-
83
-
-
60449093316
-
Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis
-
Gonzalez-Rey E, Anderson P, Gonzalez MA et al. Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis. Gut 2009;58:929–939.
-
(2009)
Gut
, vol.58
, pp. 929-939
-
-
Gonzalez-Rey, E.1
Anderson, P.2
Gonzalez, M.A.3
-
84
-
-
84867119899
-
Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy
-
Baglio SR, Pegtel DM, Baldini N. Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy. Front Physiol 2012;3:359.
-
(2012)
Front Physiol
, vol.3
, pp. 359
-
-
Baglio, S.R.1
Pegtel, D.M.2
Baldini, N.3
-
85
-
-
84883575528
-
Transplanted induced pluripotent stem cells mitigate oxidative stress and improve cardiac function through the Akt cell survival pathway in diabetic cardiomyopathy
-
Yan B, Singla DK. Transplanted induced pluripotent stem cells mitigate oxidative stress and improve cardiac function through the Akt cell survival pathway in diabetic cardiomyopathy. Mol Pharm 2013;10:3425–3432.
-
(2013)
Mol Pharm
, vol.10
, pp. 3425-3432
-
-
Yan, B.1
Singla, D.K.2
-
86
-
-
35848962732
-
Insulin-like growth factor-1 sustains stem cell mediated renal repair
-
Imberti B, Morigi M, Tomasoni S et al. Insulin-like growth factor-1 sustains stem cell mediated renal repair. J Am Soc Nephrol 2007;18:2921–2928.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 2921-2928
-
-
Imberti, B.1
Morigi, M.2
Tomasoni, S.3
-
87
-
-
84874063308
-
Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells
-
Tomasoni S, Longaretti L, Rota C et al. Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells. Stem Cells Dev 2013;22:772–780.
-
(2013)
Stem Cells Dev
, vol.22
, pp. 772-780
-
-
Tomasoni, S.1
Longaretti, L.2
Rota, C.3
-
88
-
-
0037183512
-
Human marrow stromal cell therapy for stroke in rat: Neurotrophins and functional recovery
-
Li Y, Chen J, Chen XG et al. Human marrow stromal cell therapy for stroke in rat: Neurotrophins and functional recovery. Neurology 2002;59:514–523.
-
(2002)
Neurology
, vol.59
, pp. 514-523
-
-
Li, Y.1
Chen, J.2
Chen, X.G.3
-
89
-
-
9444267155
-
Expression of insulin-like growth factor 1 and receptor in ischemic rats treated with human marrow stromal cells
-
Zhang J, Li Y, Chen J et al. Expression of insulin-like growth factor 1 and receptor in ischemic rats treated with human marrow stromal cells. Brain Res 2004;1030:19–27.
-
(2004)
Brain Res
, vol.1030
, pp. 19-27
-
-
Zhang, J.1
Li, Y.2
Chen, J.3
-
90
-
-
72949110197
-
VEGF is a mediator of the renoprotective effects of multipotent marrow stromal cells in acute kidney injury
-
Tögel F, Zhang P, Hu Z et al. VEGF is a mediator of the renoprotective effects of multipotent marrow stromal cells in acute kidney injury. J Cell Mol Med 2009;13:2109–2114.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 2109-2114
-
-
Tögel, F.1
Zhang, P.2
Hu, Z.3
-
91
-
-
78651312604
-
VEGF-modified human embryonic mesenchymal stem cell implantation enhances protection against cisplatin-induced acute kidney injury
-
Yuan L, Wu MJ, Sun HY et al. VEGF-modified human embryonic mesenchymal stem cell implantation enhances protection against cisplatin-induced acute kidney injury. Am J Physiol Renal Physiol 2011;300:F207–F218.
-
(2011)
Am J Physiol Renal Physiol
, vol.300
, pp. F207-F218
-
-
Yuan, L.1
Wu, M.J.2
Sun, H.Y.3
-
92
-
-
0037418936
-
Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats
-
Chen J, Zhang ZG, Li Y et al. Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats. Circ Res 2003;92:692–699.
-
(2003)
Circ Res
, vol.92
, pp. 692-699
-
-
Chen, J.1
Zhang, Z.G.2
Li, Y.3
-
93
-
-
78650977193
-
Hepatocyte growth factor modification promotes the amelioration effects of human umbilical cord mesenchymal stem cells on rat acute kidney injury
-
Chen Y, Qian H, Zhu W et al. Hepatocyte growth factor modification promotes the amelioration effects of human umbilical cord mesenchymal stem cells on rat acute kidney injury. Stem Cells Dev 2011;20:103–113.
-
(2011)
Stem Cells Dev
, vol.20
, pp. 103-113
-
-
Chen, Y.1
Qian, H.2
Zhu, W.3
-
94
-
-
10744229598
-
BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model
-
Kurozumi K, Nakamura K, Tamiya T et al. BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model. Mol Ther 2004;9:189–197.
-
(2004)
Mol Ther
, vol.9
, pp. 189-197
-
-
Kurozumi, K.1
Nakamura, K.2
Tamiya, T.3
-
95
-
-
76349100524
-
Therapeutic effects of human mesenchymal stem cells on traumatic brain injury in rats: Secretion of neurotrophic factors and inhibition of apoptosis
-
Kim H-J, Lee J-H, Kim S-H. Therapeutic effects of human mesenchymal stem cells on traumatic brain injury in rats: Secretion of neurotrophic factors and inhibition of apoptosis. J Neurotrauma 2010;27:131–138.
-
(2010)
J Neurotrauma
, vol.27
, pp. 131-138
-
-
Kim, H.-J.1
Lee, J.-H.2
Kim, S.-H.3
-
96
-
-
0942301277
-
Intravenous administration of marrow stromal cells (MSCs) increases the expression of growth factors in rat brain after traumatic brain injury
-
Mahmood A, Lu D, Chopp M. Intravenous administration of marrow stromal cells (MSCs) increases the expression of growth factors in rat brain after traumatic brain injury. J Neurotrauma 2004;21:33–39.
-
(2004)
J Neurotrauma
, vol.21
, pp. 33-39
-
-
Mahmood, A.1
Lu, D.2
Chopp, M.3
-
97
-
-
80054963034
-
Human umbilical cord blood mesenchymal stem cells protect mice brain after trauma*
-
Zanier ER, Montinaro M, Vigano M et al. Human umbilical cord blood mesenchymal stem cells protect mice brain after trauma*. Crit Care Med 2011;39:2501–2510.
-
(2011)
Crit Care Med
, vol.39
, pp. 2501-2510
-
-
Zanier, E.R.1
Montinaro, M.2
Vigano, M.3
-
98
-
-
84860654915
-
Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury
-
Islam MN, Das SR, Emin MT et al. Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury. Nat Med 2012;18:759–765.
-
(2012)
Nat Med
, vol.18
, pp. 759-765
-
-
Islam, M.N.1
Das, S.R.2
Emin, M.T.3
-
99
-
-
84943795327
-
Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs
-
Phinney DG, Di Giuseppe M, Njah J et al. Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs. Nat Commun 2015;6:8472.
-
(2015)
Nat Commun
, vol.6
, pp. 8472
-
-
Phinney, D.G.1
Di Giuseppe, M.2
Njah, J.3
-
100
-
-
84982850734
-
Mitochondrial transfer via tunneling nanotubes (TNT) is an important mechanism by which mesenchymal stem cells enhance macrophage phagocytosis in the in vitro and in vivo models of ARDS
-
Jackson MV, Morrison TJ, Doherty DF et al. Mitochondrial transfer via tunneling nanotubes (TNT) is an important mechanism by which mesenchymal stem cells enhance macrophage phagocytosis in the in vitro and in vivo models of ARDS. Stem Cells 2016;34:2210–2223.
-
(2016)
Stem Cells
, vol.34
, pp. 2210-2223
-
-
Jackson, M.V.1
Morrison, T.J.2
Doherty, D.F.3
-
101
-
-
85013222187
-
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
-
Witwer KW, Buzas EI, Bemis LT et al. Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J Extracell Vesicles 2013;2.
-
(2013)
J Extracell Vesicles
, vol.2
-
-
Witwer, K.W.1
Buzas, E.I.2
Bemis, L.T.3
-
102
-
-
85028270505
-
Role of cell-matrix interactions on VIC phenotype and tissue deposition in 3D PEG hydrogels
-
Gould ST, Anseth KS. Role of cell-matrix interactions on VIC phenotype and tissue deposition in 3D PEG hydrogels. J Tissue Eng Regen Med 2016;10:E443–E453.
-
(2016)
J Tissue Eng Regen Med
, vol.10
, pp. E443-E453
-
-
Gould, S.T.1
Anseth, K.S.2
-
103
-
-
84876881547
-
Regenerating the injured kidney with human umbilical cord mesenchymal stem cell-derived exosomes
-
Dorronsoro A, Robbins PD. Regenerating the injured kidney with human umbilical cord mesenchymal stem cell-derived exosomes. Stem Cell Res Ther 2013;4:39.
-
(2013)
Stem Cell Res Ther
, vol.4
, pp. 39
-
-
Dorronsoro, A.1
Robbins, P.D.2
-
104
-
-
79960944057
-
Membrane vesicles, current state-of-the-art: Emerging role of extracellular vesicles
-
Gyorgy B, Szabo TG, Pasztoi M et al. Membrane vesicles, current state-of-the-art: Emerging role of extracellular vesicles. Cell Mol Life Sci 2011;68:2667–2688.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 2667-2688
-
-
Gyorgy, B.1
Szabo, T.G.2
Pasztoi, M.3
-
105
-
-
55749112807
-
Proteomic profiling of exosomes: Current perspectives
-
Simpson RJ, Jensen SS, Lim JW. Proteomic profiling of exosomes: Current perspectives. Proteomics 2008;8:4083–4099.
-
(2008)
Proteomics
, vol.8
, pp. 4083-4099
-
-
Simpson, R.J.1
Jensen, S.S.2
Lim, J.W.3
-
106
-
-
77956404647
-
Exosomes: Extracellular organelles important in intercellular communication
-
Mathivanan S, Ji H, Simpson RJ. Exosomes: Extracellular organelles important in intercellular communication. J Proteomics 2010;73:1907–1920.
-
(2010)
J Proteomics
, vol.73
, pp. 1907-1920
-
-
Mathivanan, S.1
Ji, H.2
Simpson, R.J.3
-
107
-
-
68849129712
-
Membrane vesicles as conveyors of immune responses
-
Thery C, Ostrowski M, Segura E. Membrane vesicles as conveyors of immune responses. Nat Rev Immunol 2009;9:581–593.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 581-593
-
-
Thery, C.1
Ostrowski, M.2
Segura, E.3
-
108
-
-
84896453064
-
Mesenchymal stem cells secrete immunologically active exosomes
-
Zhang B, Yin Y, Lai RC et al. Mesenchymal stem cells secrete immunologically active exosomes. Stem Cells Dev 2014;23:1233–1244.
-
(2014)
Stem Cells Dev
, vol.23
, pp. 1233-1244
-
-
Zhang, B.1
Yin, Y.2
Lai, R.C.3
-
109
-
-
77958098024
-
Exosomes/microvesicles as a mechanism of cell-to-cell communication
-
Camussi G, Deregibus MC, Bruno S et al. Exosomes/microvesicles as a mechanism of cell-to-cell communication. Kidney Int 2010;78:838–848.
-
(2010)
Kidney Int
, vol.78
, pp. 838-848
-
-
Camussi, G.1
Deregibus, M.C.2
Bruno, S.3
-
110
-
-
34948834742
-
Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA
-
Deregibus MC, Cantaluppi V, Calogero R et al. Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA. Blood 2007;110:2440–2448.
-
(2007)
Blood
, vol.110
, pp. 2440-2448
-
-
Deregibus, M.C.1
Cantaluppi, V.2
Calogero, R.3
-
111
-
-
33646146422
-
Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: Evidence for horizontal transfer of mRNA and protein delivery
-
Ratajczak J, Miekus K, Kucia M et al. Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: Evidence for horizontal transfer of mRNA and protein delivery. Leukemia 2006;20:847–856.
-
(2006)
Leukemia
, vol.20
, pp. 847-856
-
-
Ratajczak, J.1
Miekus, K.2
Kucia, M.3
-
112
-
-
77955643809
-
Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs
-
Collino F, Deregibus MC, Bruno S et al. Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs. PLoS One 2010;5:e11803.
-
(2010)
PLoS One
, vol.5
-
-
Collino, F.1
Deregibus, M.C.2
Bruno, S.3
-
113
-
-
62749181868
-
Transfer of microRNAs by embryonic stem cell microvesicles
-
Yuan A, Farber EL, Rapoport AL et al. Transfer of microRNAs by embryonic stem cell microvesicles. PLoS One 2009;4:e4722.
-
(2009)
PLoS One
, vol.4
-
-
Yuan, A.1
Farber, E.L.2
Rapoport, A.L.3
-
114
-
-
84876875077
-
Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro
-
Zhou Y, Xu H, Xu W et al. Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro. Stem Cell Res Ther 2013;4:34.
-
(2013)
Stem Cell Res Ther
, vol.4
, pp. 34
-
-
Zhou, Y.1
Xu, H.2
Xu, W.3
-
115
-
-
84873919177
-
Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury
-
Arslan F, Lai RC, Smeets MB et al. Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury. Stem Cell Res 2013;10:301–312.
-
(2013)
Stem Cell Res
, vol.10
, pp. 301-312
-
-
Arslan, F.1
Lai, R.C.2
Smeets, M.B.3
-
116
-
-
77952293014
-
Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
-
Lai RC, Arslan F, Lee MM et al. Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury. Stem Cell Res 2010;4:214–222.
-
(2010)
Stem Cell Res
, vol.4
, pp. 214-222
-
-
Lai, R.C.1
Arslan, F.2
Lee, M.M.3
-
117
-
-
77952673860
-
Derivation and characterization of human fetal MSCs: An alternative cell source for large-scale production of cardioprotective microparticles
-
Lai RC, Arslan F, Tan SS et al. Derivation and characterization of human fetal MSCs: An alternative cell source for large-scale production of cardioprotective microparticles. J Mol Cell Cardiol 2010;48:1215–1224.
-
(2010)
J Mol Cell Cardiol
, vol.48
, pp. 1215-1224
-
-
Lai, R.C.1
Arslan, F.2
Tan, S.S.3
-
118
-
-
75649119273
-
Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs
-
Chen TS, Lai RC, Lee MM et al. Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs. Nucleic Acids Res 2010;38:215–224.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 215-224
-
-
Chen, T.S.1
Lai, R.C.2
Lee, M.M.3
-
119
-
-
84898461927
-
Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model
-
Bian S, Zhang L, Duan L et al. Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model. J Mol Med (Berl) 2014;92:387–397.
-
(2014)
J Mol Med (Berl)
, vol.92
, pp. 387-397
-
-
Bian, S.1
Zhang, L.2
Duan, L.3
-
120
-
-
79960223740
-
Mesenchymal stem cell exosome: A novel stem cell-based therapy for cardiovascular disease
-
Lai RC, Chen TS, Lim SK. Mesenchymal stem cell exosome: A novel stem cell-based therapy for cardiovascular disease. Regen Med 2011;6:481–492.
-
(2011)
Regen Med
, vol.6
, pp. 481-492
-
-
Lai, R.C.1
Chen, T.S.2
Lim, S.K.3
-
121
-
-
0027161987
-
Regulation of intercellular adhesion molecule-1 (ICAM-1) in ischemic and reperfused canine myocardium
-
Kukielka GL, Hawkins HK, Michael L et al. Regulation of intercellular adhesion molecule-1 (ICAM-1) in ischemic and reperfused canine myocardium. J Clin Invest 1993;92:1504–1516.
-
(1993)
J Clin Invest
, vol.92
, pp. 1504-1516
-
-
Kukielka, G.L.1
Hawkins, H.K.2
Michael, L.3
-
122
-
-
0038790644
-
Exosomes released during reticulocyte maturation bind to fibronectin via integrin alpha4beta1
-
Rieu S, Geminard C, Rabesandratana H et al. Exosomes released during reticulocyte maturation bind to fibronectin via integrin alpha4beta1. Eur J Biochem 2000;267:583–590.
-
(2000)
Eur J Biochem
, vol.267
, pp. 583-590
-
-
Rieu, S.1
Geminard, C.2
Rabesandratana, H.3
-
123
-
-
0344708475
-
Tetraspanin proteins mediate cellular penetration, invasion, and fusion events and define a novel type of membrane microdomain
-
Hemler ME. Tetraspanin proteins mediate cellular penetration, invasion, and fusion events and define a novel type of membrane microdomain. Annu Rev Cell Dev Biol 2003;19:397–422.
-
(2003)
Annu Rev Cell Dev Biol
, vol.19
, pp. 397-422
-
-
Hemler, M.E.1
-
124
-
-
84874831536
-
Mesenchymal stem cell exosome ameliorates reperfusion injury through proteomic complementation
-
Lai RC, Yeo RW, Tan KH et al. Mesenchymal stem cell exosome ameliorates reperfusion injury through proteomic complementation. Regen Med 2013;8:197–209.
-
(2013)
Regen Med
, vol.8
, pp. 197-209
-
-
Lai, R.C.1
Yeo, R.W.2
Tan, K.H.3
-
125
-
-
1142309743
-
New directions for protecting the heart against ischaemia-reperfusion injury: Targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway
-
Hausenloy DJ, Yellon DM. New directions for protecting the heart against ischaemia-reperfusion injury: Targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway. Cardiovasc Res 2004;61:448–460.
-
(2004)
Cardiovasc Res
, vol.61
, pp. 448-460
-
-
Hausenloy, D.J.1
Yellon, D.M.2
-
126
-
-
0033292942
-
Reperfusion injury revisited: Is there a role for growth factor signaling in limiting lethal reperfusion injury?
-
Yellon DM, Baxter GF. Reperfusion injury revisited: Is there a role for growth factor signaling in limiting lethal reperfusion injury? Trends Cardiovasc Med 1999;9:245–249.
-
(1999)
Trends Cardiovasc Med
, vol.9
, pp. 245-249
-
-
Yellon, D.M.1
Baxter, G.F.2
-
127
-
-
84866524463
-
Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome
-
Lai RC, Tan SS, Teh BJ et al. Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome. Int J Proteomics 2012;2012:971907.
-
(2012)
Int J Proteomics
, vol.2012
, pp. 971907
-
-
Lai, R.C.1
Tan, S.S.2
Teh, B.J.3
-
128
-
-
84891819825
-
Human mesenchymal stem cell microvesicles for treatment of Escherichia coli endotoxin-induced acute lung injury in mice
-
Zhu YG, Feng XM, Abbott J et al. Human mesenchymal stem cell microvesicles for treatment of Escherichia coli endotoxin-induced acute lung injury in mice. Stem Cells 2014;32:116–125.
-
(2014)
Stem Cells
, vol.32
, pp. 116-125
-
-
Zhu, Y.G.1
Feng, X.M.2
Abbott, J.3
-
129
-
-
84938866047
-
Therapeutic effects of human mesenchymal stem cell-derived microvesicles in severe pneumonia in mice
-
Monsel A, Zhu YG, Gennai S et al. Therapeutic effects of human mesenchymal stem cell-derived microvesicles in severe pneumonia in mice. Am J Respir Crit Care Med 2015;192:324–336.
-
(2015)
Am J Respir Crit Care Med
, vol.192
, pp. 324-336
-
-
Monsel, A.1
Zhu, Y.G.2
Gennai, S.3
-
130
-
-
84939568760
-
Microvesicles derived from human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation
-
Gennai S, Monsel A, Hao Q et al. Microvesicles derived from human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation. Am J Transplant 2015;15:2404–2412.
-
(2015)
Am J Transplant
, vol.15
, pp. 2404-2412
-
-
Gennai, S.1
Monsel, A.2
Hao, Q.3
-
131
-
-
84870239895
-
Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension
-
Lee C, Mitsialis SA, Aslam M et al. Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension. Circulation 2012;126:2601–2611.
-
(2012)
Circulation
, vol.126
, pp. 2601-2611
-
-
Lee, C.1
Mitsialis, S.A.2
Aslam, M.3
-
132
-
-
84906913674
-
Therapeutic effects of mesenchymal stem cell-derived microvesicles on pulmonary arterial hypertension in rats
-
Chen JY, An R, Liu ZJ et al. Therapeutic effects of mesenchymal stem cell-derived microvesicles on pulmonary arterial hypertension in rats. Acta Pharmacol Sin 2014;35:1121–1128.
-
(2014)
Acta Pharmacol Sin
, vol.35
, pp. 1121-1128
-
-
Chen, J.Y.1
An, R.2
Liu, Z.J.3
-
133
-
-
84945306718
-
Systemic administration of human bone marrow-derived mesenchymal stromal cell extracellular vesicles ameliorates Aspergillus hyphal extract-induced allergic airway inflammation in immunocompetent mice
-
Cruz FF, Borg ZD, Goodwin M et al. Systemic administration of human bone marrow-derived mesenchymal stromal cell extracellular vesicles ameliorates Aspergillus hyphal extract-induced allergic airway inflammation in immunocompetent mice. Stem Cells Transl Med 2015;4:1302–1316.
-
(2015)
Stem Cells Transl Med
, vol.4
, pp. 1302-1316
-
-
Cruz, F.F.1
Borg, Z.D.2
Goodwin, M.3
-
134
-
-
84920500515
-
Mesenchymal stem (stromal) cells for treatment of ARDS: A phase 1 clinical trial
-
Wilson JG, Liu KD, Zhuo H et al. Mesenchymal stem (stromal) cells for treatment of ARDS: A phase 1 clinical trial. Lancet Respir Med 2015;3:24–32.
-
(2015)
Lancet Respir Med
, vol.3
, pp. 24-32
-
-
Wilson, J.G.1
Liu, K.D.2
Zhuo, H.3
|