Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

Nature Communications

Volumn 6, Issue , 2015, Pages

  Phinney, Donald G ^a   Di Giuseppe, Michelangelo ^b   Njah, Joel ^b   Sala, Ernest ^c   Shiva, Sruti ^d   St Croix, Claudette M ^b,d   Stolz, Donna B ^d   Watkins, Simon C ^d   Di, Y Peter ^b   Leikauf, George D ^b   Kolls, Jay ^b   Riches, David W H ^e   Deiuliis, Giuseppe ^f   Kaminski, Naftali ^f   Boregowda, Siddaraju V ^a   McKenna, David H ^g   Ortiz, Luis A ^b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c HOSPITAL UNIVERSITARIO SON ESPASES   (Spain)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e DEPARTMENT OF MEDICINE   (United States)

^f YALE UNIVERSITY   (United States)

^g UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; RETINA S ANTIGEN; TOLL LIKE RECEPTOR; IMMUNOGLOBULIN RECEPTOR; MARCO PROTEIN, MOUSE; MYD88 PROTEIN, MOUSE; MYELOID DIFFERENTIATION FACTOR 88; TLR4 PROTEIN, MOUSE; TLR9 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9;

BIOENERGETICS; CELLS AND CELL COMPONENTS; MITOCHONDRIAL DNA; PHYSIOLOGY; PROTEIN; RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; CELL MEMBRANE; CONTROLLED STUDY; EXOSOME; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MACROPHAGE; MACROPHAGE ACTIVATION; MEMBRANE MICROPARTICLE; MESENCHYMAL STEM CELL; MITOPHAGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN DOMAIN; PROTEIN EXPRESSION; ANIMAL; ELECTRON MICROSCOPY; FLOW CYTOMETRY; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; MITOCHONDRION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SILICOSIS; ULTRASTRUCTURE; WESTERN BLOTTING;

ANIMALS; ARRESTINS; BLOTTING, WESTERN; CELL-DERIVED MICROPARTICLES; EXOSOMES; EXTRACELLULAR VESICLES; FLOW CYTOMETRY; HUMANS; MACROPHAGES; MESENCHYMAL STROMAL CELLS; MICE; MICRORNAS; MICROSCOPY, ELECTRON; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MYELOID DIFFERENTIATION FACTOR 88; OXIDATIVE STRESS; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; SILICOSIS; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS;

EID: 84943795327     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9472     Document Type: Article

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