Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 13, 2016, Pages 3621-3626

  Chan, Michael C W ^a   Kuok, Denise I T ^a   Leung, Connie Y H ^a   Hui, Kenrie P Y ^a   Valkenburg, Sophie A ^a   Lau, Eric H Y ^a   Nicholls, John M ^a   Fang, Xiaohui ^b   Guan, Yi ^a   Lee, Jae W ^b   Chan, Renee W Y ^a,c   Webster, Robert G ^d   Matthay, Michael A ^b   Peiris, J S Malik ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Acute lung injury; Alveolar fluid clearance; Avian; Influenza; Mesenchymal stromal cells

Indexed keywords

SODIUM CHLORIDE COTRANSPORTER; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANGIOTENSIN I; ATP1A1 PROTEIN, HUMAN; AUTACOID; CFTR PROTEIN, HUMAN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOKINE; FGF7 PROTEIN, HUMAN; KERATINOCYTE GROWTH FACTOR;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVIAN INFLUENZA; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; FEMALE; FLUID TRANSPORT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA A (H1N1); INFLUENZA A (H5N1); LUNG ALVEOLUS EPITHELIUM; LUNG CLEARANCE; MESENCHYMAL STROMA CELL; MIXED INFECTION; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SEASONAL INFLUENZA; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; BODY FLUID; COCULTURE; COMPLICATION; INFLUENZA; INFLUENZA A VIRUS (H5N1); LUNG ALVEOLUS; MESENCHYMAL STEM CELL TRANSPLANTATION; METABOLISM; ORTHOMYXOVIRIDAE INFECTIONS; PATHOGENICITY; PATHOPHYSIOLOGY; PERMEABILITY; PHYSIOLOGY;

ACUTE LUNG INJURY; ANGIOTENSIN I; ANIMALS; BODY FLUIDS; COCULTURE TECHNIQUES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOKINES; FEMALE; FIBROBLAST GROWTH FACTOR 7; HUMANS; INFLAMMATION MEDIATORS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA, HUMAN; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE INFECTIONS; PERMEABILITY; PULMONARY ALVEOLI; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84962128706     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1601911113     Document Type: Article

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