The many faces of the flavivirus NS5 protein in antagonism of type I interferon signaling

Journal of Virology

Volumn 91, Issue 3, 2017, Pages

  Best, Sonja M ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Antagonism; Dengue virus; Flavivirus; Interferons; JAK STAT; NS5; Tickborne encephalitis virus; West Nile virus; Yellow fever virus; Zika virus

Indexed keywords

ALPHA INTERFERON RECEPTOR; ALPHA INTERFERON RECEPTOR 1; ALPHA INTERFERON RECEPTOR 2; INTERFERON; INTERFERON REGULATORY FACTOR 9; JANUS KINASE 1; NONSTRUCTURAL PROTEIN 5; PROTEIN KINASE TYK2; STAT1 PROTEIN; STAT2 PROTEIN; TRIPARTITE MOTIF PROTEIN; TRIPARTITE MOTIF PROTEIN 23; UNCLASSIFIED DRUG; VIRUS RNA; JANUS KINASE; NS5 PROTEIN, FLAVIVIRUS; PROTEIN BINDING; STAT PROTEIN; VIRAL PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENGUE VIRUS 1; DENGUE VIRUS 2; DENGUE VIRUS 3; DENGUE VIRUS 4; DOWN REGULATION; ENZYME ACTIVATION; FLAVIVIRUS; GENE EXPRESSION REGULATION; HOST RESISTANCE; JAPANESE ENCEPHALITIS VIRUS; NONHUMAN; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA REPLICATION; TICK BORNE ENCEPHALITIS VIRUS; TRANSCRIPTION INITIATION; UPREGULATION; VIRUS TRANSMISSION; VIRUS VIRULENCE; WEST NILE VIRUS; YELLOW FEVER VIRUS; ZIKA VIRUS; ANIMAL; ANTAGONISTS AND INHIBITORS; ARTHROPOD VECTOR; CHEMISTRY; CLASSIFICATION; FLAVIVIRUS INFECTION; HOST PATHOGEN INTERACTION; HUMAN; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TRANSMISSION; VIROLOGY;

ANIMALS; ARTHROPOD VECTORS; FLAVIVIRUS; FLAVIVIRUS INFECTIONS; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERFERON TYPE I; JANUS KINASES; PROTEIN BINDING; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL NONSTRUCTURAL PROTEINS; VIRAL PROTEINS;

EID: 85010876906     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01970-16     Document Type: Article

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