Identification of residues critical for the interferon antagonist function of langat virus NS5 reveals a role for the RNA-dependent RNA polymerase domain

Journal of Virology

Volumn 81, Issue 13, 2007, Pages 6936-6946

  Park, Gregory S ^a,b   Morris, Keely L ^a   Hallett, Roselyn G ^a   Bloom, Marshall E ^a   Best, Sonja M ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIVIRUS AGENT; INTERFERON; INTERFERON ANTAGONIST; INTERFERON ANTIBODY; JANUS KINASE; METHYLTRANSFERASE; NONSTRUCTURAL PROTEIN 5A; RNA DIRECTED RNA POLYMERASE; STAT PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; ENZYME ACTIVITY; FLAVIVIRUS; IMMUNE RESPONSE; JAPANESE ENCEPHALITIS VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; VIRUS REPLICATION; WEST NILE FLAVIVIRUS;

ANIMALS; CERCOPITHECUS AETHIOPS; ENCEPHALITIS VIRUSES, TICK-BORNE; ENCEPHALITIS, TICK-BORNE; HUMANS; INTERFERONS; JANUS KINASES; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; RNA REPLICASE; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION; WEST NILE FEVER; WEST NILE VIRUS;

FLAVIVIRUS; JAPANESE ENCEPHALITIS VIRUS; LANGAT VIRUS; TICK-BORNE ENCEPHALITIS VIRUS; WEST NILE VIRUS;

EID: 34250827756     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02830-06     Document Type: Article

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