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Volumn 73, Issue 11, 1999, Pages 9247-9255

trans-Complementation analysis of the flavivirus Kunjin ns5 gene reveals an essential role for translation of its N-terminal half in RNA replication

Author keywords

[No Author keywords available]

Indexed keywords

METHYLTRANSFERASE; RNA POLYMERASE;

EID: 0032829767     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.11.9247-9255.1999     Document Type: Article
Times cited : (79)

References (36)
  • 1
    • 0030761459 scopus 로고    scopus 로고
    • Translation elongation factor-1 alpha interacts with the 3′ stem-loop region of West Nile virus genomic RNA
    • Blackwell, J. L., and M. A. Brinton. 1997. Translation elongation factor-1 alpha interacts with the 3′ stem-loop region of West Nile virus genomic RNA. J. Virol. 71:6433-6444.
    • (1997) J. Virol. , vol.71 , pp. 6433-6444
    • Blackwell, J.L.1    Brinton, M.A.2
  • 2
    • 0000445568 scopus 로고    scopus 로고
    • Molecular biology of dengue viruses
    • D. J. Gubler and G. Kuno (ed.), CAB International, Wallingford, United Kingdom
    • Chang, G.-J. 1997. Molecular biology of dengue viruses, p. 175-198. In D. J. Gubler and G. Kuno (ed.), Dengue and dengue hemorrhagic fever. CAB International, Wallingford, United Kingdom.
    • (1997) Dengue and Dengue Hemorrhagic Fever , pp. 175-198
    • Chang, G.-J.1
  • 3
    • 0031001919 scopus 로고    scopus 로고
    • RNA-protein interactions: Involvement of NS3, NS5, and 3′ noncoding regions of Japanese encephalitis virus genomic RNA
    • Chen, C.-J., M.-D. Kulo, L.-J. Chien, S.-L. Hsu, Y.-M. Wang, and J.-H. Lin. 1997. RNA-protein interactions: involvement of NS3, NS5, and 3′ noncoding regions of Japanese encephalitis virus genomic RNA. J. Virol. 71:3466-3473.
    • (1997) J. Virol. , vol.71 , pp. 3466-3473
    • Chen, C.-J.1    Kulo, M.-D.2    Chien, L.-J.3    Hsu, S.-L.4    Wang, Y.-M.5    Lin, J.-H.6
  • 4
    • 0021893927 scopus 로고
    • Replication strategy of Kunjin virus: Evidence for recycling role of replicative form RNA as template in semiconservative and asymmetric replication
    • Chu, P. W., and E. G. Westaway. 1985. Replication strategy of Kunjin virus: evidence for recycling role of replicative form RNA as template in semiconservative and asymmetric replication. Virology 140:68-79.
    • (1985) Virology , vol.140 , pp. 68-79
    • Chu, P.W.1    Westaway, E.G.2
  • 5
    • 0026494350 scopus 로고
    • Molecular and ultrastructural analysis of heavy membrane fractions associated with the replication of Kunjin virus RNA
    • Chu, P. W., and E. G. Westaway. 1992. Molecular and ultrastructural analysis of heavy membrane fractions associated with the replication of Kunjin virus RNA. Arch. Virol. 125:177-191.
    • (1992) Arch. Virol. , vol.125 , pp. 177-191
    • Chu, P.W.1    Westaway, E.G.2
  • 6
    • 0023854242 scopus 로고
    • Nucleotide and complete amino acid sequences of Kunjin virus: Definitive gene order and characteristics of the virus-specified proteins
    • Coia, G., M. D. Parker, G. Speight, M. E. Byrne, and E. G. Westaway. 1988. Nucleotide and complete amino acid sequences of Kunjin virus: definitive gene order and characteristics of the virus-specified proteins. J. Gen. Virol. 69:1-21.
    • (1988) J. Gen. Virol. , vol.69 , pp. 1-21
    • Coia, G.1    Parker, M.D.2    Speight, G.3    Byrne, M.E.4    Westaway, E.G.5
  • 7
    • 0032486596 scopus 로고    scopus 로고
    • Recombinant dengue virus type 1 NS3 protein exhibits specific viral RNA binding and NTPase activity regulated by NS5
    • Cui, T., R. J. Sugrue, Q. Xu, A. K. W. Lee, Y.-C. Chan, and J. Fu. 1998. Recombinant dengue virus type 1 NS3 protein exhibits specific viral RNA binding and NTPase activity regulated by NS5. Virology 246:409-417.
    • (1998) Virology , vol.246 , pp. 409-417
    • Cui, T.1    Sugrue, R.J.2    Xu, Q.3    Lee, A.K.W.4    Chan, Y.-C.5    Fu, J.6
  • 8
    • 0031571638 scopus 로고    scopus 로고
    • Structure of the RNA-dependent RNA polymerase of poliovirus
    • Hansen, J. L., A. M. Long, and S. C. Schultz. 1997. Structure of the RNA-dependent RNA polymerase of poliovirus. Structure 5:1109-1122.
    • (1997) Structure , vol.5 , pp. 1109-1122
    • Hansen, J.L.1    Long, A.M.2    Schultz, S.C.3
  • 9
    • 0026442838 scopus 로고
    • Identification of the domains required for direct interaction of the helicase-like and polymerase-like RNA replication proteins of brome mosaic virus
    • Kao, C. C., and P. Ahlquist. 1992. Identification of the domains required for direct interaction of the helicase-like and polymerase-like RNA replication proteins of brome mosaic virus. J. Virol. 66:7293-7302.
    • (1992) J. Virol. , vol.66 , pp. 7293-7302
    • Kao, C.C.1    Ahlquist, P.2
  • 10
    • 0029091412 scopus 로고
    • Synthesis and characterization of an infectious dengue virus type-2 RNA genome (New Guinea C strain)
    • Kapoor, M., L. Zhang, P. M. Mnhan, and R. Padmanabhan. 1995. Synthesis and characterization of an infectious dengue virus type-2 RNA genome (New Guinea C strain). Gene 162:175-180.
    • (1995) Gene , vol.162 , pp. 175-180
    • Kapoor, M.1    Zhang, L.2    Mnhan, P.M.3    Padmanabhan, R.4
  • 11
    • 0029027850 scopus 로고
    • Association between NS3 and NS5 proteins of dengue virus type 2 in the putative RNA replicase is linked to differential phosphorylation of NS5
    • Kapoor, M., L. Zhang, M. Ramachandra, J. Kusukawa, K. E. Ebner, and R. Padmanbhan. 1995. Association between NS3 and NS5 proteins of dengue virus type 2 in the putative RNA replicase is linked to differential phosphorylation of NS5. J. Biol. Chem. 270:19100-19106.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19100-19106
    • Kapoor, M.1    Zhang, L.2    Ramachandra, M.3    Kusukawa, J.4    Ebner, K.E.5    Padmanbhan, R.6
  • 12
    • 0345105196 scopus 로고    scopus 로고
    • Unpublished data
    • Khromykh, A. A. Unpublished data.
    • Khromykh, A.A.1
  • 13
    • 0028337164 scopus 로고
    • Completion of Kunjin virus RNA sequence and recovery of an infectious RNA transcribed from stably cloned full-length cDNA
    • Khromykh, A. A., and E. G. Westaway. 1994. Completion of Kunjin virus RNA sequence and recovery of an infectious RNA transcribed from stably cloned full-length cDNA. J. Virol. 68:4580-4588.
    • (1994) J. Virol. , vol.68 , pp. 4580-4588
    • Khromykh, A.A.1    Westaway, A.G.2
  • 14
    • 0031014022 scopus 로고    scopus 로고
    • Subgenomic replicons of the flavivirus Kunjin: Construction and applications
    • Khromykh, A. A., and E. G. Westaway. 1997. Subgenomic replicons of the flavivirus Kunjin: construction and applications. J. Virol. 71:1497-1505.
    • (1997) J. Virol. , vol.71 , pp. 1497-1505
    • Khromykh, A.A.1    Westaway, E.G.2
  • 15
    • 0031870247 scopus 로고    scopus 로고
    • trans-complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells
    • Khromykh, A. A., M. T. Kenney, and E. G. Westaway. 1998. trans-complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells. J. Virol. 72:7270-7279.
    • (1998) J. Virol. , vol.72 , pp. 7270-7279
    • Khromykh, A.A.1    Kenney, M.T.2    Westaway, E.G.3
  • 16
    • 0025743809 scopus 로고
    • The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses
    • Koonin, E. V. 1991. The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses. J. Gen. Virol. 72:2197-2206.
    • (1991) J. Gen. Virol. , vol.72 , pp. 2197-2206
    • Koonin, E.V.1
  • 17
    • 0027474037 scopus 로고
    • Computer-assisted identification of a putative methyltransferase domain in NS5 protein of flaviviruses and lambda 2 protein of reovirus
    • Koonin, E. V. 1993. Computer-assisted identification of a putative methyltransferase domain in NS5 protein of flaviviruses and lambda 2 protein of reovirus. J. Gen. Virol. 74:733-740.
    • (1993) J. Gen. Virol. , vol.74 , pp. 733-740
    • Koonin, E.V.1
  • 18
    • 0032976077 scopus 로고    scopus 로고
    • The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids
    • Li, H., S. Clum, S. You, K. E. Ebner, and R. Padmanabhan. 1999. The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids. J. Virol. 73:3108-3116.
    • (1999) J. Virol. , vol.73 , pp. 3108-3116
    • Li, H.1    Clum, S.2    You, S.3    Ebner, K.E.4    Padmanabhan, R.5
  • 19
    • 0030774240 scopus 로고    scopus 로고
    • trans-complementation of yellow fever virus NS1 reveals a role in early RNA replication
    • Lindenbach, B. D., and C. M. Rice. 1997. trans-complementation of yellow fever virus NS1 reveals a role in early RNA replication. J. Virol. 71:9608-9617.
    • (1997) J. Virol. , vol.71 , pp. 9608-9617
    • Lindenbach, B.D.1    Rice, C.M.2
  • 20
    • 0033034992 scopus 로고    scopus 로고
    • Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function
    • Lindenbach, B. D., and C. M. Rice. 1999. Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function. J. Virol. 73:4611-4621.
    • (1999) J. Virol. , vol.73 , pp. 4611-4621
    • Lindenbach, B.D.1    Rice, C.M.2
  • 21
    • 0029941322 scopus 로고    scopus 로고
    • Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication
    • Mackenzie, J. M., M. K. Jones, and P. R. Young. 1996. Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication. Virology 220:232-240.
    • (1996) Virology , vol.220 , pp. 232-240
    • Mackenzie, J.M.1    Jones, M.K.2    Young, P.R.3
  • 22
    • 0032486487 scopus 로고    scopus 로고
    • Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A
    • Mackenzie, J. M., A, A. Khromykh, M. K. Jones, and E. G. Westaway. 1998. Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A. Virology 245:203-215.
    • (1998) Virology , vol.245 , pp. 203-215
    • Mackenzie, J.M.1    Khromykh, A.A.2    Jones, M.K.3    Westaway, E.G.4
  • 24
    • 0028136217 scopus 로고
    • Coupling between genome translation and replication in an RNA virus
    • Novak, J. E., and K. Kirkegaard. 1994. Coupling between genome translation and replication in an RNA virus. Genes Dev. 8:1725-1737.
    • (1994) Genes Dev. , vol.8 , pp. 1725-1737
    • Novak, J.E.1    Kirkegaard, K.2
  • 25
    • 0030846169 scopus 로고    scopus 로고
    • Analysis of the interaction of viral RNA replication proteins by using two-hybrid assay
    • O'Reilly, E. K., J. D. Paul, and C. C. Kao. 1997. Analysis of the interaction of viral RNA replication proteins by using two-hybrid assay. J. Virol. 71: 7525-7532.
    • (1997) J. Virol. , vol.71 , pp. 7525-7532
    • O'Reilly, E.K.1    Paul, J.D.2    Kao, C.C.3
  • 26
    • 0032567393 scopus 로고    scopus 로고
    • Analysis of RNA-dependent RNA polymerase structure and function as guided by known polymerase structures and computer predictions of secondary structure
    • O'Reilly, E. K., and C. C. Kao. 1998. Analysis of RNA-dependent RNA polymerase structure and function as guided by known polymerase structures and computer predictions of secondary structure. Virology 252:287-303.
    • (1998) Virology , vol.252 , pp. 287-303
    • O'Reilly, E.K.1    Kao, C.C.2
  • 27
    • 0024784519 scopus 로고
    • Identification of four conserved motifs among the RNA-dependent polymerase encoding elements
    • Poch, O., I. Sauvaget, M. Delarue, and N. Tordo. 1989. Identification of four conserved motifs among the RNA-dependent polymerase encoding elements. EMBO J. 8:3867-3874.
    • (1989) EMBO J. , vol.8 , pp. 3867-3874
    • Poch, O.1    Sauvaget, I.2    Delarue, M.3    Tordo, N.4
  • 28
    • 0009927995 scopus 로고
    • Molecular cloning of poliovirus cDNA and determination of the complete nucleotide sequence of the viral genome
    • Racaniello, V. R., and D. Baltimore. 1981. Molecular cloning of poliovirus cDNA and determination of the complete nucleotide sequence of the viral genome. Proc. Natl. Acad. Sci. USA 78:4887-4891.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 4887-4891
    • Racaniello, V.R.1    Baltimore, D.2
  • 29
    • 0023830011 scopus 로고
    • Translation mapping with the flavivirus Kunjin: Gene order and anomalities in translation of NS5
    • Schrader, A. P., and E. G. Westaway. 1988. Translation mapping with the flavivirus Kunjin: gene order and anomalities in translation of NS5. Virus Res. 9:323-334.
    • (1988) Virus Res. , vol.9 , pp. 323-334
    • Schrader, A.P.1    Westaway, E.G.2
  • 30
    • 0029863798 scopus 로고    scopus 로고
    • Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity
    • Tan, B.-H., J. Fu, R. J. Sugrue, E.-H. Yap, Y.-C, Chan, and Y. H. Tan. 1996. Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity. Virology 216:317-325.
    • (1996) Virology , vol.216 , pp. 317-325
    • Tan, B.-H.1    Fu, J.2    Sugrue, R.J.3    Yap, E.-H.4    Chan, Y.-C.5    Tan, Y.H.6
  • 31
    • 0031582633 scopus 로고    scopus 로고
    • Proteins C and NS4B of the flavivirus Kunjin translocate independently into the nucleus
    • Westaway, E. G., A. A. Khromykh, M. T. Kenney, J. M. Mackenzie, and M. K. Jones. 1997. Proteins C and NS4B of the flavivirus Kunjin translocate independently into the nucleus. Virology 234:31-41.
    • (1997) Virology , vol.234 , pp. 31-41
    • Westaway, E.G.1    Khromykh, A.A.2    Kenney, M.T.3    Mackenzie, J.M.4    Jones, M.K.5
  • 32
    • 0030846512 scopus 로고    scopus 로고
    • Ultrastructure of Kunjin virus-infected cells: Colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures
    • Westaway, E. G., J. M. Mackenzie, M. T. Kenney, M. K. Jones, and A. A. Khromykh. 1997. Ultrastructure of Kunjin virus-infected cells: colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures. J. Virol. 71:6650-5661.
    • (1997) J. Virol. , vol.71 , pp. 6650-15661
    • Westaway, E.G.1    Mackenzie, J.M.2    Kenney, M.T.3    Jones, M.K.4    Khromykh, A.A.5
  • 33
    • 0033602697 scopus 로고    scopus 로고
    • Nascent flavivirus RNA co-localized in situ with double-stranded RNA in stable replication complexes
    • Westaway, E. G., A. A. Khromykh, and J. M. Mackenzie. 1999. Nascent flavivirus RNA co-localized in situ with double-stranded RNA in stable replication complexes. Virology 258:108-117.
    • (1999) Virology , vol.258 , pp. 108-117
    • Westaway, E.G.1    Khromykh, A.A.2    Mackenzie, J.M.3
  • 34
    • 0024345888 scopus 로고
    • Newly synthesized dengue-2 virus nonstructural protein NS1 is a soluble protein but becomes partially hydrophobic and membrane-associated after dimerization
    • Winkler, G., S. E. Maxwell, C. Ruemmler, and V. Stollar. 1989. Newly synthesized dengue-2 virus nonstructural protein NS1 is a soluble protein but becomes partially hydrophobic and membrane-associated after dimerization. Virology 171:302-305.
    • (1989) Virology , vol.171 , pp. 302-305
    • Winkler, G.1    Maxwell, S.E.2    Ruemmler, C.3    Stollar, V.4
  • 35
    • 0031426461 scopus 로고    scopus 로고
    • RNA signals in entero- and rhinovirus genome replication
    • Xiang, W., A. V. Paul, and E. Wimmer. 1997. RNA signals in entero- and rhinovirus genome replication. Semin. Virol. 8:256-273.
    • (1997) Semin. Virol. , vol.8 , pp. 256-273
    • Xiang, W.1    Paul, A.V.2    Wimmer, E.3
  • 36
    • 0031849664 scopus 로고    scopus 로고
    • Identification of specific nucleotide sequences within the conserved 3′-SL in the dengue type 2 virus genome required for replication
    • Zheng, L., B. Falgout, and L. Markoff. 1998. Identification of specific nucleotide sequences within the conserved 3′-SL in the dengue type 2 virus genome required for replication. J. Virol. 72:7510-7522.
    • (1998) J. Virol. , vol.72 , pp. 7510-7522
    • Zheng, L.1    Falgout, B.2    Markoff, L.3


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