메뉴 건너뛰기




Volumn 4, Issue 3, 2012, Pages 397-413

Innate immunity evasion by dengue virus

Author keywords

Interferon antagonism; NS2B3; NS5; STAT2 degradation

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 2A; NONSTRUCTURAL PROTEIN 4A; NONSTRUCTURAL PROTEIN 4B; NONSTRUCTURAL PROTEIN 5; PROTEINASE; STAT1 PROTEIN; STAT2 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84858989721     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v4030397     Document Type: Review
Times cited : (101)

References (75)
  • 1
    • 0035955628 scopus 로고    scopus 로고
    • De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase
    • Ackermann, M.; Padmanabhan, R. De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase. J. Biol. Chem. 2001, 276, 39926-39937.
    • (2001) J. Biol. Chem. , vol.276 , pp. 39926-39937
    • Ackermann, M.1    Padmanabhan, R.2
  • 2
    • 23844507858 scopus 로고    scopus 로고
    • Role of RNA structures present at the 3'UTR of dengue virus on translation, RNA synthesis, and viral replication
    • Alvarez, D.E.; de Lella Ezcurra, A.L.; Fucito, S.; Gamarnik, A.V. Role of RNA structures present at the 3'UTR of dengue virus on translation, RNA synthesis, and viral replication. Virology 2005, 339, 200-212.
    • (2005) Virology , vol.339 , pp. 200-212
    • Alvarez, D.E.1    de Lella Ezcurra, A.L.2    Fucito, S.3    Gamarnik, A.V.4
  • 4
    • 66149146738 scopus 로고    scopus 로고
    • NS5 of dengue virus mediates STAT2 binding and degradation
    • Ashour, J.; Laurent-Rolle, M.; Shi, P.Y.; Garcia-Sastre, A. NS5 of dengue virus mediates STAT2 binding and degradation. J. Virol. 2009, 83, 5408-5418.
    • (2009) J. Virol. , vol.83 , pp. 5408-5418
    • Ashour, J.1    Laurent-Rolle, M.2    Shi, P.Y.3    Garcia-Sastre, A.4
  • 7
    • 26444489068 scopus 로고    scopus 로고
    • Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist
    • Best, S.M.; Morris, K.L.; Shannon, J.G.; Robertson, S.J.; Mitzel, D.N.; Park, G.S.; Boer, E.; Wolfinbarger, J.B.; Bloom, M.E. Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist. J. Virol. 2005, 79, 12828-12839.
    • (2005) J. Virol. , vol.79 , pp. 12828-12839
    • Best, S.M.1    Morris, K.L.2    Shannon, J.G.3    Robertson, S.J.4    Mitzel, D.N.5    Park, G.S.6    Boer, E.7    Wolfinbarger, J.B.8    Bloom, M.E.9
  • 11
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell, J.E., Jr.; Kerr, I.M.; Stark, G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994, 264, 1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 13
    • 77957957039 scopus 로고    scopus 로고
    • Organelle-like membrane compartmentalization of positive-strand RNA virus replication factories
    • den Boon, J.A.; Ahlquist, P. Organelle-like membrane compartmentalization of positive-strand RNA virus replication factories. Annu. Rev. Microbiol. 2010, 64, 241-256.
    • (2010) Annu. Rev. Microbiol. , vol.64 , pp. 241-256
    • den Boon, J.A.1    Ahlquist, P.2
  • 14
    • 0032417696 scopus 로고    scopus 로고
    • Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays
    • Der, S.D.; Zhou, A.; Williams, B.R.; Silverman, R.H. Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays. Proc. Natl. Acad. Sci. USA 1998, 95, 15623-15628.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15623-15628
    • Der, S.D.1    Zhou, A.2    Williams, B.R.3    Silverman, R.H.4
  • 15
    • 0035950611 scopus 로고    scopus 로고
    • Interferon inhibits dengue virus infection by preventing translation of viral RNA through a PKR-independent mechanism
    • Diamond, M.S.; Harris, E. Interferon inhibits dengue virus infection by preventing translation of viral RNA through a PKR-independent mechanism. Virology 2001, 289, 297-311.
    • (2001) Virology , vol.289 , pp. 297-311
    • Diamond, M.S.1    Harris, E.2
  • 16
    • 0034101043 scopus 로고    scopus 로고
    • Modulation of Dengue virus infection in human cells by alpha, beta, and gamma interferons
    • Diamond, M.S.; Roberts, T.G.; Edgil, D.; Lu, B.; Ernst, J.; Harris, E. Modulation of Dengue virus infection in human cells by alpha, beta, and gamma interferons. J. Virol. 2000, 74, 4957-4966.
    • (2000) J. Virol. , vol.74 , pp. 4957-4966
    • Diamond, M.S.1    Roberts, T.G.2    Edgil, D.3    Lu, B.4    Ernst, J.5    Harris, E.6
  • 18
    • 0037013858 scopus 로고    scopus 로고
    • An RNA cap (nucleoside-2'- O-)-methyltransferase in the flavivirus RNA polymerase NS5: Crystal structure and functional characterization
    • Egloff, M.P.; Benarroch, D.; Selisko, B.; Romette, J.L.; Canard, B. An RNA cap (nucleoside-2'- O-)-methyltransferase in the flavivirus RNA polymerase NS5: Crystal structure and functional characterization. EMBO J. 2002, 21, 2757-2768.
    • (2002) EMBO J , vol.21 , pp. 2757-2768
    • Egloff, M.P.1    Benarroch, D.2    Selisko, B.3    Romette, J.L.4    Canard, B.5
  • 19
    • 35448972183 scopus 로고    scopus 로고
    • Differential effects of mutations in NS4B on West Nile virus replication and inhibition of interferon signaling
    • Evans, J.D.; Seeger, C. Differential effects of mutations in NS4B on West Nile virus replication and inhibition of interferon signaling. J. Virol. 2007, 81, 11809-11816.
    • (2007) J. Virol. , vol.81 , pp. 11809-11816
    • Evans, J.D.1    Seeger, C.2
  • 21
    • 33644752821 scopus 로고    scopus 로고
    • West Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and -independent pathways without antagonizing host defense signaling
    • Fredericksen, B.L.; Gale, M., Jr. West Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and -independent pathways without antagonizing host defense signaling. J. Virol. 2006, 80, 2913-2923.
    • (2006) J. Virol. , vol.80 , pp. 2913-2923
    • Fredericksen, B.L.1    Gale Jr., M.2
  • 25
    • 23244439085 scopus 로고    scopus 로고
    • Early alpha/beta interferon production by myeloid dendritic cells in response to UV-inactivated virus requires viral entry and interferon regulatory factor 3 but not MyD88
    • Hidmark, A.S.; McInerney, G.M.; Nordstrom, E.K.; Douagi, I.; Werner, K.M.; Liljestrom, P.; Karlsson Hedestam, G.B. Early alpha/beta interferon production by myeloid dendritic cells in response to UV-inactivated virus requires viral entry and interferon regulatory factor 3 but not MyD88. J. Virol. 2005, 79, 10376-10385.
    • (2005) J. Virol. , vol.79 , pp. 10376-10385
    • Hidmark, A.S.1    McInerney, G.M.2    Nordstrom, E.K.3    Douagi, I.4    Werner, K.M.5    Liljestrom, P.6    Karlsson Hedestam, G.B.7
  • 26
    • 20444409731 scopus 로고    scopus 로고
    • Dengue virus type 2 antagonizes IFN-alpha but not IFN-gamma antiviral effect via down-regulating Tyk2-STAT signaling in the human dendritic cell
    • Ho, L.J.; Hung, L.F.; Weng, C.Y.; Wu, W.L.; Chou, P.; Lin, Y.L.; Chang, D.M.; Tai, T.Y.; Lai, J.H. Dengue virus type 2 antagonizes IFN-alpha but not IFN-gamma antiviral effect via down-regulating Tyk2-STAT signaling in the human dendritic cell. J. Immunol. 2005, 174, 8163-8172.
    • (2005) J. Immunol. , vol.174 , pp. 8163-8172
    • Ho, L.J.1    Hung, L.F.2    Weng, C.Y.3    Wu, W.L.4    Chou, P.5    Lin, Y.L.6    Chang, D.M.7    Tai, T.Y.8    Lai, J.H.9
  • 27
    • 0035253347 scopus 로고    scopus 로고
    • Infection of human dendritic cells by dengue virus causes cell maturation and cytokine production
    • Ho, L.J.; Wang, J.J.; Shaio, M.F.; Kao, C.L.; Chang, D.M.; Han, S.W.; Lai, J.H. Infection of human dendritic cells by dengue virus causes cell maturation and cytokine production. J. Immunol. 2001, 166, 1499-1506.
    • (2001) J. Immunol. , vol.166 , pp. 1499-1506
    • Ho, L.J.1    Wang, J.J.2    Shaio, M.F.3    Kao, C.L.4    Chang, D.M.5    Han, S.W.6    Lai, J.H.7
  • 28
    • 79958098689 scopus 로고    scopus 로고
    • F1 motif of dengue virus polymerase NS5 is involved in promoter-dependent RNA synthesis
    • doi:10.1128/JVI.02343-10
    • Iglesias, N.G.; Filomatori, C.V.; Gamarnik, A.V. F1 motif of dengue virus polymerase NS5 is involved in promoter-dependent RNA synthesis. J. Virol. 2011, doi:10.1128/JVI.02343-10.
    • (2011) J. Virol.
    • Iglesias, N.G.1    Filomatori, C.V.2    Gamarnik, A.V.3
  • 29
    • 73249127604 scopus 로고    scopus 로고
    • The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure
    • Issur, M.; Geiss, B.J.; Bougie, I.; Picard-Jean, F.; Despins, S.; Mayette, J.; Hobdey, S.E.; Bisaillon, M. The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure. RNA 2009, 15, 2340-2350.
    • (2009) RNA , vol.15 , pp. 2340-2350
    • Issur, M.1    Geiss, B.J.2    Bougie, I.3    Picard-Jean, F.4    Despins, S.5    Mayette, J.6    Hobdey, S.E.7    Bisaillon, M.8
  • 30
    • 2142806767 scopus 로고    scopus 로고
    • Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization
    • Jessie, K.; Fong, M.Y.; Devi, S.; Lam, S.K.; Wong, K.T. Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization. J. Infect. Dis. 2004, 189, 1411-1418.
    • (2004) J. Infect. Dis. , vol.189 , pp. 1411-1418
    • Jessie, K.1    Fong, M.Y.2    Devi, S.3    Lam, S.K.4    Wong, K.T.5
  • 32
    • 0032889018 scopus 로고    scopus 로고
    • New mouse model for dengue virus vaccine testing
    • Johnson, A.J.; Roehrig, J.T. New mouse model for dengue virus vaccine testing. J. Virol. 1999, 73, 783-786.
    • (1999) J. Virol. , vol.73 , pp. 783-786
    • Johnson, A.J.1    Roehrig, J.T.2
  • 34
    • 0029027850 scopus 로고
    • Association between NS3 and NS5 proteins of dengue virus type 2 in the putative RNA replicase is linked to differential phosphorylation of NS5
    • Kapoor, M.; Zhang, L.; Ramachandra, M.; Kusukawa, J.; Ebner, K.E.; Padmanabhan, R. Association between NS3 and NS5 proteins of dengue virus type 2 in the putative RNA replicase is linked to differential phosphorylation of NS5. J. Biol. Chem. 1995, 270, 19100-19106.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19100-19106
    • Kapoor, M.1    Zhang, L.2    Ramachandra, M.3    Kusukawa, J.4    Ebner, K.E.5    Padmanabhan, R.6
  • 36
    • 36849074407 scopus 로고    scopus 로고
    • Monocytes, but not T or B cells, are the principal target cells for dengue virus (DV) infection among human peripheral blood mononuclear cells
    • Kou, Z.; Quinn, M.; Chen, H.; Rodrigo, W.W.; Rose, R.C.; Schlesinger, J.J.; Jin, X. Monocytes, but not T or B cells, are the principal target cells for dengue virus (DV) infection among human peripheral blood mononuclear cells. J. Med. Virol. 2008, 80, 134-146.
    • (2008) J. Med. Virol. , vol.80 , pp. 134-146
    • Kou, Z.1    Quinn, M.2    Chen, H.3    Rodrigo, W.W.4    Rose, R.C.5    Schlesinger, J.J.6    Jin, X.7
  • 37
    • 37849023828 scopus 로고    scopus 로고
    • Enabled interferon signaling evasion in an immune-competent transgenic mouse model of parainfluenza virus 5 infection
    • Kraus, T.A.; Garza, L.; Horvath, C.M. Enabled interferon signaling evasion in an immune-competent transgenic mouse model of parainfluenza virus 5 infection. Virology 2008, 371, 196-205.
    • (2008) Virology , vol.371 , pp. 196-205
    • Kraus, T.A.1    Garza, L.2    Horvath, C.M.3
  • 38
    • 0036232747 scopus 로고    scopus 로고
    • Mutations in the yellow fever virus nonstructural protein NS2A selectively block production of infectious particles
    • Kummerer, B.M.; Rice, C.M. Mutations in the yellow fever virus nonstructural protein NS2A selectively block production of infectious particles. J. Virol. 2002, 76, 4773-4784.
    • (2002) J. Virol. , vol.76 , pp. 4773-4784
    • Kummerer, B.M.1    Rice, C.M.2
  • 41
    • 33744943788 scopus 로고    scopus 로고
    • Blocking of interferon-induced Jak-Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism
    • Lin, R.J.; Chang, B.L.; Yu, H.P.; Liao, C.L.; Lin, Y.L. Blocking of interferon-induced Jak-Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism. J. Virol. 2006, 80, 5908-5918.
    • (2006) J. Virol. , vol.80 , pp. 5908-5918
    • Lin, R.J.1    Chang, B.L.2    Yu, H.P.3    Liao, C.L.4    Lin, Y.L.5
  • 42
    • 13744254078 scopus 로고    scopus 로고
    • Inhibition of interferon signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteins
    • Liu, W.J.; Wang, X.J.; Mokhonov, V.V.; Shi, P.Y.; Randall, R.; Khromykh, A.A. Inhibition of interferon signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteins. J. Virol. 2005, 79, 1934-1942.
    • (2005) J. Virol. , vol.79 , pp. 1934-1942
    • Liu, W.J.1    Wang, X.J.2    Mokhonov, V.V.3    Shi, P.Y.4    Randall, R.5    Khromykh, A.A.6
  • 44
    • 0029941322 scopus 로고    scopus 로고
    • Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication
    • Mackenzie, J.M.; Jones, M.K.; Young, P.R. Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication. Virology 1996, 220, 232-240.
    • (1996) Virology , vol.220 , pp. 232-240
    • Mackenzie, J.M.1    Jones, M.K.2    Young, P.R.3
  • 45
    • 70349432365 scopus 로고    scopus 로고
    • Dengue virus NS5 inhibits interferonalpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation
    • Mazzon, M.; Jones, M.; Davidson, A.; Chain, B.; Jacobs, M. Dengue virus NS5 inhibits interferonalpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation. J. Infect. Dis. 2009, 200, 1261-1270.
    • (2009) J. Infect. Dis. , vol.200 , pp. 1261-1270
    • Mazzon, M.1    Jones, M.2    Davidson, A.3    Chain, B.4    Jacobs, M.5
  • 46
    • 34247848008 scopus 로고    scopus 로고
    • The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner
    • Miller, S.; Kastner, S.; Krijnse-Locker, J.; Buhler, S.; Bartenschlager, R. The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner. J. Biol. Chem. 2007, 282, 8873-8882.
    • (2007) J. Biol. Chem. , vol.282 , pp. 8873-8882
    • Miller, S.1    Kastner, S.2    Krijnse-Locker, J.3    Buhler, S.4    Bartenschlager, R.5
  • 47
    • 33646851580 scopus 로고    scopus 로고
    • Subcellular localization and membrane topology of the Dengue virus type 2 Non-structural protein 4B
    • Miller, S.; Sparacio, S.; Bartenschlager, R. Subcellular localization and membrane topology of the Dengue virus type 2 Non-structural protein 4B. J. Biol. Chem. 2006, 281, 8854-8863.
    • (2006) J. Biol. Chem. , vol.281 , pp. 8854-8863
    • Miller, S.1    Sparacio, S.2    Bartenschlager, R.3
  • 50
    • 79851492362 scopus 로고    scopus 로고
    • RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection
    • doi:10.1371/journal.pntd.0000926
    • Nasirudeen, A.M.; Wong, H.H.; Thien, P.; Xu, S.; Lam, K.P.; Liu, D.X. RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection. PLoS Negl. Trop. Dis. 2011, 5, doi:10.1371/journal.pntd.0000926.
    • (2011) PLoS Negl. Trop. Dis. , pp. 5
    • Nasirudeen, A.M.1    Wong, H.H.2    Thien, P.3    Xu, S.4    Lam, K.P.5    Liu, D.X.6
  • 51
    • 0041707804 scopus 로고    scopus 로고
    • De novo synthesis of negative-strand RNA by Dengue virus RNA-dependent RNA polymerase in vitro: Nucleotide, primer, and template parameters
    • Nomaguchi, M.; Ackermann, M.; Yon, C.; You, S.; Padmanabhan, R. De novo synthesis of negative-strand RNA by Dengue virus RNA-dependent RNA polymerase in vitro: Nucleotide, primer, and template parameters. J. Virol. 2003, 77, 8831-8842.
    • (2003) J. Virol. , vol.77 , pp. 8831-8842
    • Nomaguchi, M.1    Ackermann, M.2    Yon, C.3    You, S.4    Padmanabhan, R.5
  • 52
    • 0036284219 scopus 로고    scopus 로고
    • STAT2 acts as a host range determinant for species-specific paramyxovirus interferon antagonism and simian virus 5 replication
    • Parisien, J.P.; Lau, J.F.; Horvath, C.M. STAT2 acts as a host range determinant for species-specific paramyxovirus interferon antagonism and simian virus 5 replication. J. Virol. 2002, 76, 6435-6441.
    • (2002) J. Virol. , vol.76 , pp. 6435-6441
    • Parisien, J.P.1    Lau, J.F.2    Horvath, C.M.3
  • 53
    • 0033230707 scopus 로고    scopus 로고
    • Murine Stat2 is uncharacteristically divergent
    • Park, C.; Lecomte, M.J.; Schindler, C. Murine Stat2 is uncharacteristically divergent. Nucleic Acids Res. 1999, 27, 4191-4199.
    • (1999) Nucleic Acids Res , vol.27 , pp. 4191-4199
    • Park, C.1    Lecomte, M.J.2    Schindler, C.3
  • 54
    • 34250827756 scopus 로고    scopus 로고
    • Identification of residues critical for the interferon antagonist function of Langat virus NS5 reveals a role for the RNA-dependent RNA polymerase domain
    • Park, G.S.; Morris, K.L.; Hallett, R.G.; Bloom, M.E.; Best, S.M. Identification of residues critical for the interferon antagonist function of Langat virus NS5 reveals a role for the RNA-dependent RNA polymerase domain. J. Virol. 2007, 81, 6936-6946.
    • (2007) J. Virol. , vol.81 , pp. 6936-6946
    • Park, G.S.1    Morris, K.L.2    Hallett, R.G.3    Bloom, M.E.4    Best, S.M.5
  • 55
    • 79952237300 scopus 로고    scopus 로고
    • STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor
    • doi:10.1371/journal.ppat.1001297
    • Perry, S.T.; Buck, M.D.; Lada, S.M.; Schindler, C.; Shresta, S. STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor. PLoS Pathog. 2011, 7, doi:10.1371/journal.ppat.1001297.
    • (2011) PLoS Pathog , pp. 7
    • Perry, S.T.1    Buck, M.D.2    Lada, S.M.3    Schindler, C.4    Shresta, S.5
  • 56
    • 74049115561 scopus 로고    scopus 로고
    • Dengue virus virulence and transmission determinants
    • Rico-Hesse, R. Dengue virus virulence and transmission determinants. Curr. Top. Microbiol. Immunol. 2011, 338, 45-55.
    • (2011) Curr. Top. Microbiol. Immunol. , vol.338 , pp. 45-55
    • Rico-Hesse, R.1
  • 57
    • 77956859036 scopus 로고    scopus 로고
    • Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex
    • Rodriguez-Madoz, J.R.; Belicha-Villanueva, A.; Bernal-Rubio, D.; Ashour, J.; Ayllon, J.; Fernandez-Sesma, A. Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex. J. Virol. 2010, 84, 9760-9774.
    • (2010) J. Virol. , vol.84 , pp. 9760-9774
    • Rodriguez-Madoz, J.R.1    Belicha-Villanueva, A.2    Bernal-Rubio, D.3    Ashour, J.4    Ayllon, J.5    Fernandez-Sesma, A.6
  • 58
    • 77950824984 scopus 로고    scopus 로고
    • Dengue virus inhibits the production of type I interferon in primary human dendritic cells
    • Rodriguez-Madoz, J.R.; Bernal-Rubio, D.; Kaminski, D.; Boyd, K.; Fernandez-Sesma, A. Dengue virus inhibits the production of type I interferon in primary human dendritic cells. J. Virol. 2010, 84, 4845-4850.
    • (2010) J. Virol. , vol.84 , pp. 4845-4850
    • Rodriguez-Madoz, J.R.1    Bernal-Rubio, D.2    Kaminski, D.3    Boyd, K.4    Fernandez-Sesma, A.5
  • 59
    • 79955542915 scopus 로고    scopus 로고
    • A diverse range of gene products are effectors of the type I interferon antiviral response
    • Schoggins, J.W.; Wilson, S.J.; Panis, M.; Murphy, M.Y.; Jones, C.T.; Bieniasz, P.; Rice, C.M. A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 2011, 472, 481-485.
    • (2011) Nature , vol.472 , pp. 481-485
    • Schoggins, J.W.1    Wilson, S.J.2    Panis, M.3    Murphy, M.Y.4    Jones, C.T.5    Bieniasz, P.6    Rice, C.M.7
  • 60
    • 1542317760 scopus 로고    scopus 로고
    • Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less critical
    • Shresta, S.; Kyle, J.L.; Snider, H.M.; Basavapatna, M.; Beatty, P.R.; Harris, E. Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less critical. J. Virol. 2004, 78, 2701-2710.
    • (2004) J. Virol. , vol.78 , pp. 2701-2710
    • Shresta, S.1    Kyle, J.L.2    Snider, H.M.3    Basavapatna, M.4    Beatty, P.R.5    Harris, E.6
  • 63
    • 0029863798 scopus 로고    scopus 로고
    • Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity
    • Tan, B.H.; Fu, J.; Sugrue, R.J.; Yap, E.H.; Chan, Y.C.; Tan, Y.H. Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity. Virology 1996, 216, 317-325.
    • (1996) Virology , vol.216 , pp. 317-325
    • Tan, B.H.1    Fu, J.2    Sugrue, R.J.3    Yap, E.H.4    Chan, Y.C.5    Tan, Y.H.6
  • 65
    • 62149139785 scopus 로고    scopus 로고
    • Human TLR3 recognizes dengue virus and modulates viral replication in vitro
    • Tsai, Y.T.; Chang, S.Y.; Lee, C.N.; Kao, C.L. Human TLR3 recognizes dengue virus and modulates viral replication in vitro. Cell. Microbiol. 2009, 11, 604-615.
    • (2009) Cell. Microbiol. , vol.11 , pp. 604-615
    • Tsai, Y.T.1    Chang, S.Y.2    Lee, C.N.3    Kao, C.L.4
  • 66
    • 58149402643 scopus 로고    scopus 로고
    • Dengue virus regulates type I interferon signalling in a strain-dependent manner in human cell lines
    • Umareddy, I.; Tang, K.F.; Vasudevan, S.G.; Devi, S.; Hibberd, M.L.; Gu, F. Dengue virus regulates type I interferon signalling in a strain-dependent manner in human cell lines. J. Gen. Virol. 2008, 89, 3052-3062.
    • (2008) J. Gen. Virol. , vol.89 , pp. 3052-3062
    • Umareddy, I.1    Tang, K.F.2    Vasudevan, S.G.3    Devi, S.4    Hibberd, M.L.5    Gu, F.6
  • 67
    • 78649681550 scopus 로고    scopus 로고
    • A balance between circular and linear forms of the dengue virus genome is crucial for viral replication
    • Villordo, S.M.; Alvarez, D.E.; Gamarnik, A.V. A balance between circular and linear forms of the dengue virus genome is crucial for viral replication. RNA 2010, 16, 2325-2335.
    • (2010) RNA , vol.16 , pp. 2325-2335
    • Villordo, S.M.1    Alvarez, D.E.2    Gamarnik, A.V.3
  • 69
    • 70649102178 scopus 로고    scopus 로고
    • RNA-binding activity of hepatitis C virus NS4B: A novel target for small molecule inhibitors
    • Welsch, C.; Zeuzem, S. RNA-binding activity of hepatitis C virus NS4B: A novel target for small molecule inhibitors. Gastroenterology 2009, 137, 2170-2172.
    • (2009) Gastroenterology , vol.137 , pp. 2170-2172
    • Welsch, C.1    Zeuzem, S.2
  • 70
    • 38849166538 scopus 로고    scopus 로고
    • Tick-borne encephalitis virus NS5 associates with membrane protein scribble and impairs interferon-stimulated JAK-STAT signalling
    • Werme, K.; Wigerius, M.; Johansson, M. Tick-borne encephalitis virus NS5 associates with membrane protein scribble and impairs interferon-stimulated JAK-STAT signalling. Cell. Microbiol. 2008, 10, 696-712.
    • (2008) Cell. Microbiol. , vol.10 , pp. 696-712
    • Werme, K.1    Wigerius, M.2    Johansson, M.3
  • 72
    • 53249130750 scopus 로고    scopus 로고
    • Mouse models of dengue virus infection and disease
    • Yauch, L.E.; Shresta, S. Mouse models of dengue virus infection and disease. Antiviral. Res. 2008, 80, 87-93.
    • (2008) Antiviral. Res. , vol.80 , pp. 87-93
    • Yauch, L.E.1    Shresta, S.2
  • 74
    • 34447273319 scopus 로고    scopus 로고
    • Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases
    • Zhou, Z.; Hamming, O.J.; Ank, N.; Paludan, S.R.; Nielsen, A.L.; Hartmann, R. Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases. J. Virol. 2007, 81, 7749-7758.
    • (2007) J. Virol. , vol.81 , pp. 7749-7758
    • Zhou, Z.1    Hamming, O.J.2    Ank, N.3    Paludan, S.R.4    Nielsen, A.L.5    Hartmann, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.