Dengue Virus Co-opts UBR4 to Degrade STAT2 and Antagonize Type I Interferon Signaling

PLoS Pathogens

Volumn 9, Issue 3, 2013, Pages

  Morrison, Juliet ^a   Laurent Rolle, Maudry ^a   Maestre, Ana M ^a   Rajsbaum, Ricardo ^a   Pisanelli, Giuseppe ^a,b   Simon, Viviana ^a   Mulder, Lubbertus C F ^a   Fernandez Sesma, Ana ^a   García Sastre, Adolfo ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; NONSTRUCTURAL PROTEIN 5; SHORT HAIRPIN RNA; STAT2 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UBR4 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENGUE; DENGUE VIRUS; FLOW CYTOMETRY; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNE EVASION; IMMUNOFLUORESCENCE TEST; IMMUNOPRECIPITATION; MASS SPECTROMETRY; NONHUMAN; NORMAL HUMAN; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN PURIFICATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VIRUS REPLICATION; WESTERN BLOTTING;

ANIMALS; CALMODULIN-BINDING PROTEINS; CELL LINE; CERCOPITHECUS AETHIOPS; CYTOSKELETAL PROTEINS; DENGUE VIRUS; HUMANS; IMMUNE EVASION; INTERFERON TYPE I; PROTEIN BINDING; SIGNAL TRANSDUCTION; STAT2 TRANSCRIPTION FACTOR; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS;

DENGUE VIRUS;

EID: 84875994162     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003265     Document Type: Article

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