The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling

Journal of Virology

Volumn 84, Issue 7, 2010, Pages 3503-3515

  Laurent Rolle, Maudry ^a   Boer, Elena F ^b   Lubick, Kirk J ^b   Wolfinbarger, James B ^b   Carmody, Aaron B ^b   Rockx, Barry ^b   Liu, Wenjun ^c   Ashour, Joseph ^a   Shupert, W Lesley ^b   Holbrook, Michael R ^d,f   Barrett, Alan D ^d   Mason, Peter W ^d,e   Bloom, Marshall E ^b   García Sastre, Adolfo ^a   Khromykh, Alexander A ^c   Best, Sonja M ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d University of Texas Medical Branch School of Medicine   (United States)

^e NOVARTIS VACCINES AND DIAGNOSTICS   (United States)

^f BATTELLE MEMORIAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE; NONSTRUCTURAL PROTEIN 5; STAT1 PROTEIN; STAT2 PROTEIN;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; KUNJIN VIRUS; NEWCASTLE DISEASE PARAMYXOVIRUS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VIROGENESIS; VIRUS INFECTION; VIRUS REPLICATION; VIRUS STRAIN; WEST NILE FLAVIVIRUS;

ANIMALS; CERCOPITHECUS AETHIOPS; HUMANS; INTERFERON TYPE I; JANUS KINASES; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS; WEST NILE VIRUS;

ARTHROPODA; KUNJIN VIRUS; NEWCASTLE DISEASE VIRUS; WEST NILE VIRUS;

EID: 77949373371     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01161-09     Document Type: Article

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