Nuclear localization of dengue virus nonstructural protein 5 does not strictly correlate with efficient viral RNA replication and inhibition of type I interferon signaling

Journal of Virology

Volumn 87, Issue 8, 2013, Pages 4545-4557

  Kumar, Anil ^a   Bühler, Sandra ^a   Selisko, Barbara ^b   Davidson, Andrew ^c   Mulder, Klaas ^a   Canard, Bruno ^b   Miller, Sven ^a,d   Bartenschlager, Ralf ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b CNRS   (France)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; METHYLTRANSFERASE; NONSTRUCTURAL PROTEIN 5; RNA DIRECTED DNA POLYMERASE; STAT2 PROTEIN; VIRUS RNA;

ALPHA BETA NUCLEAR LOCALIZATION SIGNAL; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; MOLECULAR MODEL; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA REPLICATION; SIGNAL TRANSDUCTION; VIRUS CELL INTERACTION; VIRUS PATHOGENESIS; VIRUS REPLICATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE; CELL NUCLEUS; DENGUE VIRUS; DNA MUTATIONAL ANALYSIS; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERFERON TYPE I; NUCLEAR LOCALIZATION SIGNALS; PROTEOLYSIS; RNA, VIRAL; SIGNAL TRANSDUCTION; STAT2 TRANSCRIPTION FACTOR; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

DENGUE VIRUS;

EID: 84875802186     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03083-12     Document Type: Article

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