The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway

Cellular and Molecular Immunology

Volumn 14, Issue 1, 2017, Pages 127-142

  Ratsimandresy, Rojo A ^a   Indramohan, Mohanalaxmi ^a   Dorfleutner, Andrea ^a   Stehlik, Christian ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

antimicrobial peptides; IL 18; IL 22; IL 22BP; inflammasome; inflammatory bowel disease; microbiome; Reg3

Indexed keywords

AIM2 PROTEIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 22; INTERLEUKIN 22 BINDING PROTEIN; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN KINASE B; REG3B PROTEIN; REG3G PROTEIN; REGULATOR PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG; AIM2 PROTEIN, MOUSE; DEXTRAN SULFATE; DNA BINDING PROTEIN; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; LECTIN; PANCREATITIS-ASSOCIATED PROTEIN; PAP PROTEIN, MOUSE; PEPTIDE; PROTEIN; TUMOR ANTIGEN; TUMOR MARKER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SUSCEPTIBILITY; CELL PROLIFERATION; COLITIS; COLORECTAL CANCER; CONTROLLED STUDY; CRYPT CELL; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DYSBIOSIS; ENZYME ACTIVATION; HOMEOSTASIS; INTESTINAL HOMEOSTASIS; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STEADY STATE; STOMACH PROTECTION; ANIMAL; BACTERIUM; BIOLOGICAL MODEL; C57BL MOUSE; CHEMICALLY INDUCED; IMMUNOLOGY; INTESTINE; INTESTINE CELL; METABOLISM; PATHOLOGY; WOUND HEALING;

ANIMALS; ANTIGENS, NEOPLASM; BACTERIA; BIOMARKERS, TUMOR; COLITIS; DEXTRAN SULFATE; DNA-BINDING PROTEINS; DYSBIOSIS; ENTEROCYTES; HOMEOSTASIS; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKINS; INTESTINES; LECTINS, C-TYPE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; PEPTIDES; PROTEINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; WOUND HEALING;

EID: 85007603424     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2016.35     Document Type: Article

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