Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

Cell Metabolism

Volumn 24, Issue 6, 2016, Pages 795-806

  Mills, Kathryn F ^a   Yoshida, Shohei ^b   Stein, Liana R ^a   Grozio, Alessia ^a   Kubota, Shunsuke ^a   Sasaki, Yo ^a   Redpath, Philip ^c   Migaud, Marie E ^c   Apte, Rajendra S ^a   Uchida, Koji ^b   Yoshino, Jun ^a   Imai, Shin ichiro ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Oriental Yeast Co Ltd   (Japan)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

aging; anti aging; energy metabolism; eye function; glucose metabolism; insulin sensitivity; mitochondria; NAD+; NAD+ precursor; nicotinamide mononucleotide; NMN

Indexed keywords

INSULIN; LIPID; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE;

AEROBIC METABOLISM; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE DENSITY; CONTROLLED STUDY; ENERGY METABOLISM; EYE DISEASE; GENE EXPRESSION; INSULIN SENSITIVITY; LIPID ANALYSIS; LIPID BLOOD LEVEL; LOCOMOTION; MALE; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PHENOTYPE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; SKELETAL MUSCLE; WEIGHT GAIN; WILD TYPE; ANIMAL; BLOOD; BONE MARROW CELL; C57BL MOUSE; CELL RESPIRATION; DARKNESS; DRINKING; DRUG EFFECTS; EATING; FOOD; GENE EXPRESSION REGULATION; GENETICS; LYMPHOCYTE; METABOLISM; MITOCHONDRION; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; TIME FACTOR;

ADMINISTRATION, ORAL; AGING; ANIMALS; BONE DENSITY; CELL RESPIRATION; DARKNESS; DRINKING; EATING; ENERGY METABOLISM; FOOD; GENE EXPRESSION REGULATION; INSULIN; LIPIDS; LYMPHOCYTES; MALE; MICE, INBRED C57BL; MITOCHONDRIA; MUSCLE, SKELETAL; MYELOID CELLS; NAD; NICOTINAMIDE MONONUCLEOTIDE; PHYSICAL CONDITIONING, ANIMAL; TIME FACTORS; WEIGHT GAIN;

EID: 85004028301     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.09.013     Document Type: Article

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