Differences in the distribution, phenotype and gene expression of subretinal microglia/macrophages in C57BL/6N (Crb1rd8/rd8) versus C57BL6/J (Crb1wt/wt) mice

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Aredo, Bogale ^a   Zhang, Kaiyan ^a,b   Chen, Xiao ^a,c   Wang, Cynthia Xin Zhao ^a   Li, Tao ^a   Ufret Vincenty, Rafael L ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b HAINAN PROVINCIAL PEOPLE S HOSPITAL   (China)

^c WUHAN GENERAL HOSPITAL OF GUANGZHOU COMMAND   (China)

Author keywords

activation; aging; CD16; Crb1; gene expression; Iba 1; macrophages; microglia; rd8; subretinal

Indexed keywords

ADAPTOR PROTEIN; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; CD16 ANTIGEN; CD200 RECEPTOR; CD32 ANTIGEN; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; IONIZED CALCIUM BINDING ADAPTOR 1; IONIZED CALCIUM BINDING ADAPTOR 2; MACROPHAGE MANNOSE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCYTE CHEMOTACTIC PROTEIN 1; RECEPTOR; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; AIF1 PROTEIN, MOUSE; CALCIUM BINDING PROTEIN; CELL SURFACE RECEPTOR; CRB1 PROTEIN, MOUSE; FC RECEPTOR; LECTIN; MANNOSE BINDING LECTIN; MANNOSE RECEPTOR; NERVE PROTEIN;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; C57BL/6N MOUSE; CELLULAR DISTRIBUTION; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CRB1 GENE; EYE FUNDUS; GENE; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MACROPHAGE; MICROGLIA; MOUSE; MOUSE MUTANT; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PIGMENT EPITHELIUM; PROTEIN EXPRESSION; RETINA; RETINA DEGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRAIN DIFFERENCE; UPREGULATION; WILD TYPE MOUSE; AGE; ANIMAL; C57BL MOUSE; CELL COUNT; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; NERVE TRACT; PATHOLOGY; RETINAL PIGMENT EPITHELIUM; TRANSGENIC MOUSE; ULTRASTRUCTURE;

AGE FACTORS; ANIMALS; CALCIUM-BINDING PROTEINS; CELL COUNT; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; LECTINS, C-TYPE; MACROPHAGES; MANNOSE-BINDING LECTINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROFILAMENT PROTEINS; MICROGLIA; MUTATION; NERVE TISSUE PROTEINS; NEURAL PATHWAYS; PHENOTYPE; RECEPTORS, CELL SURFACE; RECEPTORS, IGG; RETINA; RETINAL DEGENERATION; RETINAL PIGMENT EPITHELIUM;

EID: 84924919017     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-014-0221-4     Document Type: Article

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