Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death

Brain Research

Volumn 1643, Issue , 2016, Pages 1-9

  Wang, Xiaonan ^a   Hu, Xuejun ^a   Yang, Yang ^a   Takata, Toshihiro ^b   Sakurai, Takashi ^c  

^a CHINA MEDICAL UNIVERSITY   (China)

^b SAISEIKAI NAKATSU HOSPITAL   (Japan)

^c NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

Alzheimer's disease; Cognitive impairment; Neuronal death; Nicotinamide mononucleotide; ROS

Indexed keywords

3 ACETYLPYRIDINE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[1-42] OLIGOMER; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE; OLIGOMER; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; WATER; ADENOSINE TRIPHOSPHATE; AMYLOID BETA-PROTEIN (1-42); NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT; SUPEROXIDE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; ATTENUATION; BRAIN METABOLISM; CELL SURVIVAL; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFICACY; DRUG INFUSION; ENERGY METABOLISM; HIPPOCAMPAL SLICE; LONG TERM POTENTIATION; MALE; MORRIS WATER MAZE TEST; NERVE CELL CULTURE; NERVE CELL NECROSIS; NERVE CELL PLASTICITY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; ORGANOTYPIC HIPPOCAMPAL SLICE; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; ANIMAL; CELL DEATH; CHEMICALLY INDUCED; COGNITIVE DYSFUNCTION; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; HIPPOCAMPUS; MAZE TEST; MEMORY; METABOLISM; MITOCHONDRION; NERVE CELL; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE; WISTAR RAT;

ADENOSINE TRIPHOSPHATE; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CELL DEATH; COGNITIVE DYSFUNCTION; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; MAZE LEARNING; MEMORY; MITOCHONDRIA; NAD; NEURONS; NEUROPROTECTIVE AGENTS; NICOTINAMIDE MONONUCLEOTIDE; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUPEROXIDES; TISSUE CULTURE TECHNIQUES;

EID: 84968563033     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2016.04.060     Document Type: Article

References (43)

1. C.C. Alano, W. Ying, and R.A. Swanson Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition J. Biol. Chem. 279 2004 18895 18902
2. + depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death J. Neurosci. 30 2010 2967 2978
3. P. Belenky, K.L. Bogan, and C. Brenner NAD+ metabolism in health and disease Trends Biochem. Sci. 32 2006 12 19
4. P.M. Canas, L.O. Porciuncula, G.M. Cunha, C.G. Silva, N.J. Machado, J.M. Oliveira, and R.A. Cunha Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway J. Neurosci. 29 2009 14741 14751
5. Q.S. Chen, W.Z. Wei, T. Shimahara, and C.W. Xie Alzheimer amyloid beta-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus Neurobiol. Learn. Mem. 77 2002 354 371
6. M. Dumont, and M.F. Beal Neuroprotective strategies involving ROS in Alzheimer disease Free Radic. Biol. Med. 51 2011 1014 1026
7. Y. Gong, L. Chang, K.L. Viola, P.N. Lacor, M.P. Lambert, C.E. Finch, G.A. Krafft, and W.L. Klein Alzheimer's disease-affected brain: presence of oligomeric a beta ligands (ADDLs) suggests a molecular basis for reversible memory loss Proc. Natl. Acad. Sci. USA 100 2003 10417 10422
8. I. Guidi, D. Galimberti, S. Lonati, C. Novembrino, F. Bamonti, M. Tiriticco, C. Fenoglio, E. Venturelli, P. Baron, N. Bresolin, and E. Scarpini Oxidative imbalance in patients with mild cognitive impairment and Alzheimer's disease Neurobiol. Aging 27 2006 262 269
9. J. Hardy, and D.J. Selkoe The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics Science 297 2002 353 356
10. F.Q. He, B.Y. Qiu, X.H. Zhang, T.K. Li, Q. Xie, D.J. Cui, X.L. Huang, and H.T. Gan Tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β (1-42) Brain Res. 1384 2011 89 96
11. F. Huang, M.C. Vemuri, and J.S. Schneider Modulation of ATP levels alters the mode of hydrogen peroxide-induced cell death in primary cortical cultures: effects of putative neuroprotective agents Brain Res. 997 2004 79 88
12. S. Imai Dissecting systemic control of metabolism and aging in the NAD World: the importance of SIRT1 and NAMPT-mediated NAD biosynthesis FEBS Lett. 585 2011 1657 1662
13. J.W. Jama, L. Launer, J.C. Witteman, J.H. den Breeijen, M.M. Breteler, D.E. Grobbee, and A. Hofman Dietary antioxidants and cognitive function in a population-based sample of older persons Rotterdam Study Am. J. Epidemiol. 144 1996 275 280
14. D. Kapogiannis, and M.P. Mattson Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease Lancet Neurol. 10 2011 187 198
15. H. Katsuki, C. Nakanishi, H. Saito, and N. Matsuki Biphasic effect of hyfrogen peroxide on field potentials in rat hippocampal slices Eur. J. Pharmacol. 337 1997 213 218
16. D. Kim, M.D. Nguyen, M.M. Dobbin, A. Fischer, F. Sananbenesi, J.T. Rodgers, I. Delalle, J.A. Baur, G. Sui, S.M. Armour, P. Puigserver, D.A. Sinclair, and L.H. Tsai SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis EMBO J. 26 2007 3169 3179
17. S. Lesne, M.T. Koh, L. Kotilinek, R. Kayed, C.G. Glabe, A. Yang, M. Gallagher, and K.H. Ashe A specific amyloid-beta protein assembly in the brain impairs memory Nature 440 2006 352 357
18. J. Li, C. Wang, J.H. Zhang, J.M. Cai, Y.P. Cao, and X.J. Sun Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress Brain Res. 1328 2010 152 161
19. J.D. Macklis, and R.D. Madison Progressive incorporation of propidium iodide in cultured mouse neurons correlates with declining electrophysiological status: a fluorescence scale of membrane integrity J. Neurosci. Methods 31 1990 43 46
20. M.P. Mattson Pathways towards and away from Alzheimer's disease Nature 430 2004 631 639
21. Y. Morel, and R. Barouki Repression of gene expression by oxidative stress Biochem J. 342 1999 481 496
22. Y. Okada Recovery of neuronal activity and high-energy compound level after complete and prolonged brain ischemia Brain Res. 72 1974 346 349
23. W.J. Perrig, P. Perrig, and H.B. Stähelin The relation between antioxidants and memory performance in the old and very old J. Am. Geriatr. Soc. 445 1997 718 724
24. M. Pittelli, R. Felici, V. Pitozzi, L. Giovannelli, E. Bigagli, F. Cialdai, G. Romano, F. Moroni, and A. Chiarugi Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis Mol. Pharmacol. 80 2011 1136 1146
25. 1-40 induces NMDA-dependert degradation of postsynaptic density-95 at glutamatergic synapses J. Neurosci. 25 2005 11061 11070
26. C.A. Rottkamp, A. Nunomura, K. Hirai, L.M. Sayre, G. Perry, and M.A. Smith Will antioxidants fulfill their expectations for the treatment of Alzheimer disease? Mech. Ageing Dev. 116 2000 169 179
27. W. Qin, T. Yang, L. Ho, Z. Zhao, J. Wang, L. Chen, W. Zhao, M. Thiyagarajan, D. MacGrogan, J.T. Rodgers, P. Puigserver, J. Sadoshima, H. Deng, S. Pedrini, S. Gandy, A.A. Sauve, and G.M. Pasinetti Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction J. Biol. Chem. 281 2006 21745 21754
28. B.J. Sander, F.J. Oelshlegel Jr., and G.J. Brewer Quantitative analysis of pyridine nucleotides in and blood cells: a single-step extraction procedure Anal. Biochem. 71 1976 29 36
29. C.T. Sheline, M.M. Behrens, and D.W. Choi Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD(+) and inhibition of glycolysis J. Neurosci. 20 2000 3139 3146
30. W.W. Smith, M. Gorospe, and J.W. Kusiak Signaling mechanisms underlying abeta toxicity: potential therapeutic targets for Alzheimer's disease CNS Neurol. Disord. Drug. Targets 5 2006 355 361
31. L.R. Stein, D.F. Wozniak, J.T. Dearborn, S. Kubota, R.S. Apte, Y. Izumi, C.F. Zorumski, and S. Imai Expression of Nampt in hippocampal and cortical excitatory neurons is critical for cognitive function J. Neurosci. 34 2014 5800 5815
32. T. Ma, C.A. Hoeffer, H. Wong, C.A. Massaad, P. Zhou, C. Iadecola, M.P. Murphy, R.G. Pautler, and E. Klann Amyloidβ-induced impairments in hippocampal synaptic plasticity are rescued by decreasing mitochondrial superoxide J. Neurosci. 31 2011 5589 5595
33. W.M. Tilton, C. Seaman, D. Carriero, and S. Piomolli Regulation of glycosis in the erythrocyte: role of the lactate/pyruvate and NAD/NADH ratios J. Lab. Clin. Med. 118 1991 146 152
34. D.M. Walsh, I. Klyubin, J.V. Fadeeva, W.K. Cullen, R. Anwyl, M.S. Wolfe, M.J. Rowan, and D.J. Selkoe Naturally secreted oligomers of amyloid beta potently inhibit hippocampal long-term potentiation in vivo Nature 416 2002 535 539
35. C.N. Wang, C.W. Chi, Y.L. Lin, C.F. Chen, and Y.J. Shiao The neuroprotective effects of phytoestrogens on amyloid β protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons J. Biol. Chem. 276 2001 5287 5295
36. S. Wang, Z. Xing, P.S. Vosler, H. Yin, W. Li, F. Zhang, A.P. Signore, R.A. Stetler, Y. Gao, and J. Chen Cellular NAD replenishment confers marked neuroprotection against ischemic cell death: role of enhanced DNA repair Stroke 39 2008 2587 2595
37. X.N. Wang, T. Takata, T. Sakurai, and K. Yokono Different effects of monocarboxylates on neuronal survival and β-amyloid toxicity Eur. J. Neurosci. 26 2007 2142 2150
38. B.L. Wilkinson, and G.E. Landreth The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease J. Neuroinflamm. 3 2006 30
39. W. Xia, Z. Wang, Q. Wang, J. Han, C. Zhao, Y. Hong, L. Zeng, L. Tang, and W. Ying Roles of NAD(+)/NADH and NADP(+)/NADPH in cell death Curr. Pharm. Des. 15 2009 12 19
40. W. Ying, P. Garnier, and R.A. Swanson NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes Biochem. Biophys. Res. Commun. 308 2003 809 813
41. W. Ying NAD+ and NADH in cellular functions and cell death Front. Biosci. 11 2006 3129 3148
42. W. Ying NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences Antioxid. Redox Signal 10 2008 179 206
43. J. Yoshino, K.F. Mills, M.J. Yoon, and S. Imai Nicotinamide mononucleotide, a key NAD (+) intermediate, treats the pathophysiology of diet- and age-induceddiabetes in mice Cell Metab. 14 2011 528 536