Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

Aging Cell

Volumn 15, Issue 3, 2016, Pages 522-530

  de Picciotto, Natalie E ^a   Gano, Lindsey B ^a,c   Johnson, Lawrence C ^a   Martens, Christopher R ^a   Sindler, Amy L ^a,d   Mills, Kathryn F ^b   Imai, Shin ichiro ^b   Seals, Douglas R ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

Arterial stiffness; Endothelial dysfunction; NAD+; Oxidative stress; SIRT1

Indexed keywords

3 NITROTYROSINE; COLLAGEN TYPE 1; ELASTIN; MANGANESE SUPEROXIDE DISMUTASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE; NITRIC OXIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SIRTUIN 1; SUPEROXIDE; TEMPOL; SUPEROXIDE DISMUTASE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTERIAL STIFFNESS; ARTERY DIAMETER; ARTICLE; CAROTID ARTERY; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; EX VIVO STUDY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULSE WAVE; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; YOUNG MODULUS; ANIMAL; C57BL MOUSE; DIETARY SUPPLEMENT; DRUG EFFECTS; ELASTICITY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; VASCULAR ENDOTHELIUM; VASODILATATION;

AGING; ANIMALS; AORTA; DIETARY SUPPLEMENTS; ELASTICITY; ENDOTHELIUM, VASCULAR; MALE; MICE, INBRED C57BL; NICOTINAMIDE MONONUCLEOTIDE; NITRIC OXIDE; OXIDATIVE STRESS; SIRTUIN 1; SUPEROXIDE DISMUTASE; VASCULAR STIFFNESS; VASODILATION;

EID: 84960352089     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12461     Document Type: Article

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