Noninvasive and targeted delivery of therapeutics to the brain using focused ultrasound

Neuropharmacology

Volumn 120, Issue , 2017, Pages 20-37

  Poon, Charissa ^a,c   McMahon, Dallan ^b,c   Hynynen, Kullervo ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c Canada   (Canada)

Author keywords

Blood brain barrier; Drug delivery; Focused ultrasound; Microbubbles; MRI ; Noninvasive surgery

Indexed keywords

ADENO ASSOCIATED VIRUS VECTOR; ALCOHOL; AMYLOID BETA PROTEIN ANTIBODY; ANTINEOPLASTIC AGENT; ARABINOSE; BRAIN DERIVED NEUROTROPHIC FACTOR; CARMUSTINE; DIMETHYL SULFOXIDE; DODECYL SULFATE SODIUM; DOXORUBICIN; ECHO CONTRAST MEDIUM; LIPOSOME; MAGNETIC NANOPARTICLE; MANNITOL; METHOTREXATE; NANOCARRIER; PERFLUTREN; SMALL INTERFERING RNA; SULFUR HEXAFLUORIDE; TEMOZOLOMIDE; CENTRAL NERVOUS SYSTEM AGENTS;

ALZHEIMER DISEASE; ASTROCYTE; BLOOD BRAIN BARRIER; BONE CANCER; DENTATE GYRUS; DRUG BRAIN LEVEL; DRUG DELIVERY SYSTEM; DRUG EFFECT; ESSENTIAL TREMOR; FOCUSED ULTRASOUND; GLIOBLASTOMA; GLIOMA; HIGH INTENSITY FOCUSED ULTRASOUND; HIPPOCAMPUS; HUMAN; HYDROGEL; MEAN RESIDENCE TIME; MICROBUBBLE; MICROGLIA; NERVOUS SYSTEM DEVELOPMENT; NEUROMODULATION; NON INVASIVE PROCEDURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROSTATE CANCER; REVIEW; ULTRASOUND; UTERUS MYOMA; ANIMAL; BRAIN; CENTRAL NERVOUS SYSTEM DISEASES; DRUG EFFECTS; ECHOGRAPHY; PHYSIOLOGY; PROCEDURES;

ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM AGENTS; CENTRAL NERVOUS SYSTEM DISEASES; DRUG DELIVERY SYSTEMS; HUMANS; ULTRASONOGRAPHY;

EID: 84998981017     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2016.02.014     Document Type: Review

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