Blood-Brain Barrier (BBB) Disruption Using a Diagnostic Ultrasound Scanner and Definity® in Mice

Ultrasound in Medicine and Biology

Volumn 35, Issue 8, 2009, Pages 1298-1308

  Bing, Kristin Frinkley ^a   Howles, Gabriel P ^a,b   Qi, Yi ^b   Palmeri, Mark L ^a   Nightingale, Kathryn R ^a  

^a Duke University   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Blood brain barrier; Contrast agent; Drug delivery; Magnetic resonance imaging; Ultrasound

Indexed keywords

BLOOD CELLS; BLOOD-BRAIN BARRIER; CLINICAL DIAGNOSTICS; CLINICAL UTILITY; CONTRAST AGENT; CONTRAST TO NOISE RATIO; DEFINITY; DIAGNOSTIC ULTRASOUND; DOPPLER; HIGHER FREQUENCIES; INJECTION TIME; ISOFLURANE; LOWER FREQUENCIES; MAGNETIC RESONANCE CONTRAST AGENTS; MECHANICAL INDEXES; MOUSE MODELS; MR IMAGES; PULSE DURATIONS; PULSE REPETITION FREQUENCIES; PULSED WAVE; SPATIAL LOCATION; THERAPEUTIC AGENTS; TRANSMIT FREQUENCY; ULTRASONIC FREQUENCY; ULTRASOUND; ULTRASOUND IMAGES; ULTRASOUND IMAGING;

ACOUSTIC WAVES; BLOOD; CELL MEMBRANES; DRUG DELIVERY; GELATION; MAGNETIC RESONANCE; MAGNETIC RESONANCE IMAGING; MEDICAL IMAGING; PIEZOELECTRIC TRANSDUCERS; PULSE GENERATORS; SCANNING; ULTRASONIC TRANSDUCERS; ULTRASONIC TRANSMISSION; ULTRASONICS;

ULTRASONIC IMAGING;

GADOLINIUM PENTETATE; ISOFLURANE; PERFLUTREN;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; ECHOGRAPHY; MEMBRANE DAMAGE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SIGNAL NOISE RATIO; SKULL; ULTRASOUND SCANNER; ULTRASOUND TRANSDUCER;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CONTRAST MEDIA; ECHOENCEPHALOGRAPHY; FLUOROCARBONS; GADOLINIUM DTPA; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MICE; MICE, INBRED C57BL; ULTRASONOGRAPHY, INTERVENTIONAL;

EID: 67650266248     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2009.03.012     Document Type: Article

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